1. Clinical practice guidelines for autoimmune hepatitis.
- Author
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Ohira, Hiromasa, Takahashi, Atsushi, Zeniya, Mikio, Abe, Masanori, Arinaga‐Hino, Teruko, Joshita, Satoru, Takaki, Akinobu, Nakamoto, Nobuhiro, Kang, Jong‐Hon, Suzuki, Yoshiyuki, Sogo, Tsuyosi, Inui, Ayano, Koike, Kazuhiko, Harada, Kenichi, Nakamoto, Yasunari, Kondo, Yasuteru, Genda, Takuya, Tsuneyama, Koichi, Matsui, Tsuyoshi, and Tanaka, Atsushi
- Subjects
CHRONIC active hepatitis ,AUTOIMMUNE hepatitis ,PROGNOSIS ,LIVER failure ,MULTIPLE organ failure ,MEDICAL practice - Abstract
Histology B Recommendations: b The typical histology of AIH is the chronic active hepatitis, along with characteristic to AIH histological findings, such as interface hepatitis, hepatocellular rosette, large numbers of plasma cells, and emperipolesis.52 However, all these findings have low disease specificity, making it difficult to diagnose AIH based on histology alone. SUPPORTING INFORMATION MEMO: PATHOLOGICAL FINDINGS OF ACUTE HEPATITIS PHASE AIH Some cases of acute hepatitis phase AIH have clinical presentations that resemble acute hepatitis. SUPPORTING INFORMATION MEMO: CLINICAL CHARACTERISTICS OF ACUTE HEPATITIS PHASE AIH Among AIH cases which develop like acute hepatitis, are the "acute hepatitis phase AIH" lacking any chronic findings in the liver tissue. B Recommendations: b Some cases of AIH exhibit an "acute presentation" with clinical courses and liver function test patterns that resemble acute hepatitis, severe hepatitis, or acute liver failure (fulminant hepatitis/late-onset hepatic failure (LOHF)) (recommendation grade: 1, evidence strength: B). [Extracted from the article]
- Published
- 2022
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