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Your search keyword '"Savelyev, E. N."' showing total 3 results
Start Over Author "Savelyev, E. N." Search Limiters Peer Reviewed Topic catalysis Publication Year Range Last 3 years
3 results on '"Savelyev, E. N."'

3. Copper catalysis in the synthesis of N-naphthyl and N-quinolinyl derivatives of adamantane-containing amines.

Author

Kuliukhina, D. S., Averin, A. D., Abel, A. S., Maloshitskaya, O. A., Savelyev, E. N., Orlinson, B. S., Novakov, I. A., and Beletskaya, I. P.

Subjects
ADAMANTANE derivatives, AMINE derivatives, CATALYSIS, COPPER, NANOPARTICLE size, AMINES, AMINATION, PROLINE
Abstract

N-(Het)arylation of adamantane-containing amines with halonaphthalenes and haloquinolines catalyzed by either CuI or copper nanoparticles with an average size of 25 nm in the presence of 2-isobutyrylcyclohexanone, rac-BINOL, and l-proline as a ligand and Cs2CO3 as a base in DMSO at 110 °C was studied. The reactions proceed smoothly with 2-iodonaphthalene and 6-iodoquinoline, the possibility of successful reactions with 6- and 3-bromoquinolines was also shown. In the case of 1-bromonaphthalene, 5- and 8-bromoquinolines, only Pd-catalyzed amination can provide the high yields of the products. An alternative possibility of C(sp2)—N bond formation was studied employing the Chan—Lam reaction with of 2-naphthaleneboronic acid and pinacolates of 6- and 3-quinolineboronic acids. [ABSTRACT FROM AUTHOR]

Published
2023
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