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22 results on '"Donati, Daniele"'

1. Città strategiche

Author

Donati, Daniele

Subjects
Metropolitan cities, Multilevel system, Differentiation, Functions, Organization, Efficiency, bic Book Industry Communication::L Law::LN Laws of Specific jurisdictions::LNK Environment, transport & planning law, bic Book Industry Communication::R Earth sciences, geography, environment, planning::RP Regional & area planning::RPC Urban & municipal planning
Abstract

The administration of metropolitan cities is a complicated issue that, in every country, has forced legislators and interpreters to face problems previously unseen. This complexity, descending by the uniqueness of those places, imposes to law scholars an analysis not limited to the study of their necessarily differentiated forms of government and management. Moving beyond the mere consideration of the material element of the Territory and it’s role in identifying the voters community, it’s necessary to explore and understand the cutting-edge dynamics that agitate in urban centers: assuming this point of view, the book debates, also in a comparative and historical perspective, what is here labeled as “the metropolitan issue”. Starting from the unresolved determination of their role in a multilevel system, here is scrutinized the actual legal framework of these local authorities, situated in an intermediate position between regions and municipal bodies, offering a review of the possible alternative interpretations, but holding firm the idea of metropolitan cities as aimed primarily at the strategic planning of the economic and social development of the whole area. The result is their characterization as systemic entities, more capable of relationships than regulation, whose autonomy has been attributed and has to be interpreted and evaluated in the key of efficiency in performances and satisfaction of those who live and work in those places.

Published
2023

3. Nurses' compliance to standard precautions prior to and during COVID‐19.

Author

Dobrina, Raffaella, Donati, Daniele, Giangreco, Manuela, De Benedictis, Anna, Schreiber, Silvana, Bicego, Livia, Scarsini, Sara, Buchini, Sara, KWOK, Stephen Wai Hang, and Lam, Simon Ching

Subjects
*RESEARCH, *WELL-being, *KRUSKAL-Wallis Test, *PROFESSIONS, *INDUSTRIAL safety, *NURSING, *CROSS-sectional method, *DECONTAMINATION (From gases, chemicals, etc.), *MANN Whitney U Test, *PROTECTIVE clothing, *INFECTION control, *MEDICAL protocols, *HOSPITAL nursing staff, *LEGAL compliance, *CHI-squared test, *DESCRIPTIVE statistics, *UNIVERSAL precautions (Health), *MEDICAL waste disposal, *COVID-19 pandemic
Abstract

Aims: To measure nurses' compliance with standard precautions during the COVID‐19 pandemic, compare findings with previous assessments and describe the barriers affecting nurses' compliance. Background: Healthcare providers' compliance with standard precautions is still limited worldwide. Implementation of infection control policies in hospitals is needed internationally, especially during a pandemic. Surprisingly, studies exploring nurses' compliance with standard precautions are lacking during COVID‐19. Methods: A multicenter cross‐sectional study was adopted in two Italian hospitals. Nurses' compliance with standard precautions was measured through The Compliance with Standard Precautions Scale (Italian version). An open‐ended question explored the barriers to nurses' compliance with standard precautions. Reporting, followed the STROBE guidelines. Results: A total of 201 nurses were enrolled in 2020. Nurses' compliance with standard precautions was suboptimal. A statistically significant improvement in the compliance rate with standard precautions was observed between pre‐ and during COVID‐19 assessments. High compliance was found in the appropriate use of surgical masks, gloves and sharps disposal. Nurses perceived personal, structural and organizational barriers to standard precautions adherence. Conclusion: Nurses' compliance with standard precautions was not 100%, and different factors impeded nurses to work safely. Our findings provide institutional leaders and educators with the basis for implementing policies to optimize nurse safety, well‐being and patient care. Implications for nursing and health policies: Nurses have the right to work safely, and when the shortage of personal protective equipment and nurses during an emergency threatens healthcare quality worldwide, policymakers are challenged to act by establishing an effective allocation of resources for consistent compliance with standard precautions. Moreover, nurses should actively engage in the implementation of infection control policies to improve safe behaviours among citizens and students accessing hospitals. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Supplementary Figures 1-6 and Tables 1-2 from Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Author

Ardini, Elena, primary, Menichincheri, Maria, primary, Banfi, Patrizia, primary, Bosotti, Roberta, primary, De Ponti, Cristina, primary, Pulci, Romana, primary, Ballinari, Dario, primary, Ciomei, Marina, primary, Texido, Gemma, primary, Degrassi, Anna, primary, Avanzi, Nilla, primary, Amboldi, Nadia, primary, Saccardo, Maria Beatrice, primary, Casero, Daniele, primary, Orsini, Paolo, primary, Bandiera, Tiziano, primary, Mologni, Luca, primary, Anderson, David, primary, Wei, Ge, primary, Harris, Jason, primary, Vernier, Jean-Michel, primary, Li, Gang, primary, Felder, Eduard, primary, Donati, Daniele, primary, Isacchi, Antonella, primary, Pesenti, Enrico, primary, Magnaghi, Paola, primary, and Galvani, Arturo, primary

Published
2023
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5. Data from Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Author

Ardini, Elena, primary, Menichincheri, Maria, primary, Banfi, Patrizia, primary, Bosotti, Roberta, primary, De Ponti, Cristina, primary, Pulci, Romana, primary, Ballinari, Dario, primary, Ciomei, Marina, primary, Texido, Gemma, primary, Degrassi, Anna, primary, Avanzi, Nilla, primary, Amboldi, Nadia, primary, Saccardo, Maria Beatrice, primary, Casero, Daniele, primary, Orsini, Paolo, primary, Bandiera, Tiziano, primary, Mologni, Luca, primary, Anderson, David, primary, Wei, Ge, primary, Harris, Jason, primary, Vernier, Jean-Michel, primary, Li, Gang, primary, Felder, Eduard, primary, Donati, Daniele, primary, Isacchi, Antonella, primary, Pesenti, Enrico, primary, Magnaghi, Paola, primary, and Galvani, Arturo, primary

Published
2023
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6. Supplementary Materials and Methods from Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Author

Ardini, Elena, primary, Menichincheri, Maria, primary, Banfi, Patrizia, primary, Bosotti, Roberta, primary, De Ponti, Cristina, primary, Pulci, Romana, primary, Ballinari, Dario, primary, Ciomei, Marina, primary, Texido, Gemma, primary, Degrassi, Anna, primary, Avanzi, Nilla, primary, Amboldi, Nadia, primary, Saccardo, Maria Beatrice, primary, Casero, Daniele, primary, Orsini, Paolo, primary, Bandiera, Tiziano, primary, Mologni, Luca, primary, Anderson, David, primary, Wei, Ge, primary, Harris, Jason, primary, Vernier, Jean-Michel, primary, Li, Gang, primary, Felder, Eduard, primary, Donati, Daniele, primary, Isacchi, Antonella, primary, Pesenti, Enrico, primary, Magnaghi, Paola, primary, and Galvani, Arturo, primary

Published
2023
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7. Supplementary Figure S1 from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases

Author

Fogliatto, Gianpaolo, primary, Gianellini, Laura, primary, Brasca, Maria G., primary, Casale, Elena, primary, Ballinari, Dario, primary, Ciomei, Marina, primary, Degrassi, Anna, primary, De Ponti, Anna, primary, Germani, Massimiliano, primary, Guanci, Marco, primary, Paolucci, Mauro, primary, Polucci, Paolo, primary, Russo, Micaela, primary, Sola, Francesco, primary, Valsasina, Barbara, primary, Visco, Carlo, primary, Zuccotto, Fabio, primary, Donati, Daniele, primary, Felder, Eduard, primary, Pesenti, Enrico, primary, Galvani, Arturo, primary, Mantegani, Sergio, primary, and Isacchi, Antonella, primary

Published
2023
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8. Supplementary Methods from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases

Author

Fogliatto, Gianpaolo, primary, Gianellini, Laura, primary, Brasca, Maria G., primary, Casale, Elena, primary, Ballinari, Dario, primary, Ciomei, Marina, primary, Degrassi, Anna, primary, De Ponti, Anna, primary, Germani, Massimiliano, primary, Guanci, Marco, primary, Paolucci, Mauro, primary, Polucci, Paolo, primary, Russo, Micaela, primary, Sola, Francesco, primary, Valsasina, Barbara, primary, Visco, Carlo, primary, Zuccotto, Fabio, primary, Donati, Daniele, primary, Felder, Eduard, primary, Pesenti, Enrico, primary, Galvani, Arturo, primary, Mantegani, Sergio, primary, and Isacchi, Antonella, primary

Published
2023
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9. Supplementary Table S1 from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases

Author

Fogliatto, Gianpaolo, primary, Gianellini, Laura, primary, Brasca, Maria G., primary, Casale, Elena, primary, Ballinari, Dario, primary, Ciomei, Marina, primary, Degrassi, Anna, primary, De Ponti, Anna, primary, Germani, Massimiliano, primary, Guanci, Marco, primary, Paolucci, Mauro, primary, Polucci, Paolo, primary, Russo, Micaela, primary, Sola, Francesco, primary, Valsasina, Barbara, primary, Visco, Carlo, primary, Zuccotto, Fabio, primary, Donati, Daniele, primary, Felder, Eduard, primary, Pesenti, Enrico, primary, Galvani, Arturo, primary, Mantegani, Sergio, primary, and Isacchi, Antonella, primary

Published
2023
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10. Supplementary Figures 1-14, Tables 1-4, Methods, References from Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase

Author

Colombo, Riccardo, primary, Caldarelli, Marina, primary, Mennecozzi, Milena, primary, Giorgini, Maria Laura, primary, Sola, Francesco, primary, Cappella, Paolo, primary, Perrera, Claudia, primary, Depaolini, Stefania Re, primary, Rusconi, Luisa, primary, Cucchi, Ulisse, primary, Avanzi, Nilla, primary, Bertrand, Jay Aaron, primary, Bossi, Roberto Tiberio, primary, Pesenti, Enrico, primary, Galvani, Arturo, primary, Isacchi, Antonella, primary, Colotta, Francesco, primary, Donati, Daniele, primary, and Moll, Jürgen, primary

Published
2023
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11. Data from Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase

Author

Colombo, Riccardo, primary, Caldarelli, Marina, primary, Mennecozzi, Milena, primary, Giorgini, Maria Laura, primary, Sola, Francesco, primary, Cappella, Paolo, primary, Perrera, Claudia, primary, Depaolini, Stefania Re, primary, Rusconi, Luisa, primary, Cucchi, Ulisse, primary, Avanzi, Nilla, primary, Bertrand, Jay Aaron, primary, Bossi, Roberto Tiberio, primary, Pesenti, Enrico, primary, Galvani, Arturo, primary, Isacchi, Antonella, primary, Colotta, Francesco, primary, Donati, Daniele, primary, and Moll, Jürgen, primary

Published
2023
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12. Neutralizing Antibodies against SARS-CoV-2 Beta and Omicron Variants Inhibition Comparison after BNT162b2 mRNA Booster Doses with a New PETIA sVNT Assay

Author

Fogolari, Marta, primary, Leoni, Bruno Daniele, additional, De Cesaris, Marina, additional, Italiano, Rita, additional, Davini, Flavio, additional, Miccoli, Ginevra Azzurra, additional, Donati, Daniele, additional, Clerico, Luigi, additional, Stanziale, Andrea, additional, Savini, Giovanni, additional, Petrosillo, Nicola, additional, Ciccozzi, Massimo, additional, Sommella, Lorenzo, additional, Riva, Elisabetta, additional, Fazii, Paolo, additional, and Angeletti, Silvia, additional

Published
2023
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14. Stereoselective synthesis of 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids

Author

Casuscelli, Francesco, primary, Ardini, Elena, additional, Avanzi, Nilla, additional, Badari, Alessandra, additional, Casale, Elena, additional, Disingrini, Teresa, additional, Donati, Daniele, additional, Ermoli, Antonella, additional, Felder, Eduard R., additional, Galvani, Arturo, additional, Isacchi, Antonella, additional, Menichincheri, Maria, additional, Montemartini, Marisa, additional, Orrenius, Christian, additional, Piutti, Claudia, additional, Salom, Barbara, additional, and Papeo, Gianluca, additional

Published
2022
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15. Diritto e amministrazione della sanità - Approfondimenti a.a. 2020-2021

Author

Gola, Marcella, Acri, Pietro, Donati, Daniele, and Tubertini, Claudia

Subjects
IUS/10 Diritto amministrativo, Master in Diritto Sanitario
Abstract

Il presente volume raccoglie i risultati dei progetti di ricerca elaborati dagli allievi del Master Universitario di I Livello in Diritto e amministrazione della sanità, svoltosi nell’a.a. 2020/2021 presso la Scuola di Specializzazione in Studi sull’Amministrazione Pubblica dell’Alma Mater Studiorum- Università di Bologna. Gli studi redatti si propongono di analizzare alcune tematiche del settore medico-sanitario, ritenute di particolare rilevanza e attualità in quanto il perdurare dell’emergenza legata alla pandemia da SARS-CoV-2 ha fatto emergere nuove esigenze e problematicità per la cui risoluzione occorre individuare gli strumenti adeguati, spesso basandosi sulla riconsiderazione dei modelli utilizzati in precedenza. I temi selezionati riguardano: Gli strumenti di governo coordinato della sanità (a cura di Claudia Tubertini); Vaccini e pandemia: problematiche giuridiche (a cura di Marcella Gola); Public procurement in sanità tra programmazione e flessibilità (a cura di Pietro Acri); L'amministrazione sanitaria tra scienza e diritti dei cittadini (a cura di Daniele Donati).

Published
2022
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16. Identification of unprecedented ATP-competitive choline kinase inhibitors

Author

Quartieri, Francesca, Nesi, Marcella, Avanzi, Nilla R., Borghi, Daniela, Casale, Elena, Corti, Emiliana, Cucchi, Ulisse, Donati, Daniele, Fasolini, Marina, Felder, Eduard R., Galvani, Arturo, Giorgini, Maria L., Lomolino, Antonio, Menichincheri, Maria, Orrenius, Christian, Perrera, Claudia, Re Depaolini, Stefania, Riccardi-Sirtori, Federico, Salsi, Enea, Isacchi, Antonella, and Gnocchi, Paola

Published
2021
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17. Detection of a SARS-CoV-2 P.1.1 variant lacking N501Y in a vaccinated health care worker in Italy

Author

Angeletti, Silvia, primary, Giovanetti, Marta, additional, Fogolari, Marta, additional, De Florio, Lucia, additional, Francesconi, Maria, additional, Veralli, Roberta, additional, Antonelli, Francesca, additional, Donati, Daniele, additional, Miccoli, Ginevra Azzurra, additional, Fonseca, Vagner, additional, Benedetti, Francesca, additional, Zella, Davide, additional, Riva, Elisabetta, additional, and Ciccozzi, Massimo, additional

Published
2021
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20. Design and Synthesis of Novel Tricyclic Benzoxazines as Potent 5-HT1A/B/DReceptor Antagonists Leading to the Discovery of 6-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide (GSK588045)

Author

Bromidge, Steven M., Arban, Roberto, Bertani, Barbara, Bison, Silvia, Borriello, Manuela, Cavanni, Paolo, Dal Forno, Giovanna, Di-Fabio, Romano, Donati, Daniele, Fontana, Stefano, Gianotti, Massimo, Gordon, Laurie J., Granci, Enrica, Leslie, Colin P., Moccia, Luca, Pasquarello, Alessandra, Sartori, Ilaria, Sava, Anna, Watson, Jeannette M., Worby, Angela, Zonzini, Laura, and Zucchelli, Valeria

Abstract

Bioisoteric replacement of the metabolically labile N-methyl amide group of a series of benzoxazinones with small heterocyclic rings has led to novel series of fused tricyclic benzoxazines which are potent 5-HT1A/B/Dreceptor antagonists with and without concomitant human serotonin transporter (hSerT) activity. Optimizing against multiple parameters in parallel identified 6-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide (GSK588045) as a potent 5-HT1A/B/Dreceptor antagonist with a high degree of selectivity over human ether-à-go-go related gene (hERG) potassium channels, favorable pharmacokinetics, and excellent activity in vivo in rodent pharmacodynamic (PD) models. On the basis of its outstanding overall profile, this compound was progressed as a clinical candidate with the ultimate aim to assess its potential as a faster acting antidepressant/anxiolytic with reduced side-effect burden.

Published
2024
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21. Correction to Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Author

Menichincheri, Maria, Ardini, Elena, Magnaghi, Paola, Avanzi, Nilla, Banfi, Patrizia, Bossi, Roberto, Buffa, Laura, Canevari, Giulia, Ceriani, Lucio, Colombo, Maristella, Corti, Luca, Donati, Daniele, Fasolini, Marina, Felder, Eduard, Fiorelli, Claudio, Fiorentini, Francesco, Galvani, Arturo, Isacchi, Antonella, Borgia, Andrea Lombardi, Marchionni, Chiara, Nesi, Marcella, Orrenius, Christian, Panzeri, Achille, Pesenti, Enrico, Rusconi, Luisa, Saccardo, Maria Beatrice, Vanotti, Ermes, Perrone, Ettore, and Orsini, Paolo

Published
2024
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22. The digital art paradox: understanding its issues and dynamics

Author

Nascimento, Beatriz Lopes, Melo, Alexandre, and Donati, Daniele

Subjects
Immateriality, Art world, Digital art, Imaterialidade, Direito de autor -- Copyright, Arte digital, Mundo da arte, Rejeição, Autenticidade, Ciências Sociais::Outras Ciências Sociais [Domínio/Área Científica], Mainstream, Authenticity, Disavowal
Abstract

Over the years there has been a clear separation – the disavowal - from the mainstream art world and digital art. The main triggering point of this dissertation is to understand the paradoxical nature of this relationship from the start, coming from the basilar literature and data observation. Digital art, despite being a concept that began in the 1950s, still lacks consensus from the big art institutions, the academia, and the overall audience, to this date. As it can be categorized, this movement has a complex ongoing history that can help to understand the intrinsic aspects of digital art that have been creating this gap for all these years. The central aspect that explains the digital art paradox is the relationship between its external factors – the art institutions and organizations – and the internal factors – the immateriality issue and the problem of authenticity and copyright in the digital world. The present dissertation attempts to analyze this relationship and to draw some considerations for the future of art in the growing and thriving digital era. Ao longo dos anos tem havido uma clara separação – a resistência – entre o mundo da arte convencional e a arte digital. O ponto desencadeante desta dissertação é compreender a natureza paradoxal desta relação desde o início, proveniente da literatura basilar e da observação de dados. A arte digital, apesar de ser um conceito que começou nos anos 50, ainda carece de consenso por parte das grandes instituições de arte, da academia, e do público em geral, até esta data. Este movimento, como pode ser categorizado, tem uma história complexa e em construção, que pode ajudar a compreender os aspetos intrínsecos da arte digital que estão a criar esta lacuna ao longo de todos estes anos. O aspeto central que explica o paradoxo da arte digital é a relação entre os seus fatores externos - as instituições e organizações de arte - e os internos - a questão da imaterialidade e o problema da autenticidade e dos direitos de autor no mundo digital. A presente dissertação tenta analisar esta relação e traçar algumas considerações para o futuro da arte na crescente e próspera era digital.

Published
2022

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