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32 results on '"Lucini, Daniela"'

6. HEBE project: Healthy aging versus inflamm-aging: The role of physical exercise in modulating the biomarkers of age-associated and environmentally determined chronic diseases, study protocol.

Author

Bianchi, Francesca, Biganzoli, Elia Mario, Bollati, Valentina, Clerici, Mario, Lucini, Daniela, Mandò, Chiara, and Rota, Federica

Subjects
RESEARCH protocols, AGING, CELLULAR aging, CHRONIC diseases, HUMAN body
Abstract

Inflamm-aging refers to the chronic low-grade inflammation that occurs with aging and cellular senescence, and it is linked to various diseases. Understanding the markers involved in inflammation and aging, as well as their interaction with environmental factors and bodily control mechanisms, can provide crucial tools for assessing the resilience (i.e. the ability to adapt and improve) of the human body, particularly in the presence of chronic degenerative conditions or vulnerable life stages, that place the individual and the community to which he belongs in a state of potential fragility. HEBE focuses on physical exercise, along with nutritional and lifestyle recommendations, to reduce systemic inflammation and promote healthy aging. HEBE encompasses multiple research lines (LR). In the ongoing LR1 ("proof of concept"), healthy lifestyle recommendations were provided to University of Milan employees, and changes in quality of life and well-being were assessed using a specialized questionnaire. The first 100 eligible subjects, who expressed their willingness to participate, underwent a personalized physical exercise protocol based on clinical and objective assessments. Biomedical samples were collected at baseline (T0) and follow-up (T1) to establish a shared biobank and identify non-invasive biomarkers that monitor the impact of physical exercise on individual characteristics such as cardiovascular and metabolic health. Subsequently (LR2-LR10), the proof of concept findings will be expanded to include various conditions of vulnerability such as obesity, cancer, endocrine disorders, cardiovascular diseases, infertility, functional syndromes, respiratory disorders, neurodegenerative diseases, and autoimmune conditions. The research lines will leverage the expertise of the 94 participating investigators to form a collaborative network that maximizes the potential for investigation and knowledge exchange. This approach fosters a culture of health promotion and disease prevention. ClinicalTrials.gov Identifier: NCT05815732. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Effects of an online exercise training on autonomic and metabolic control in children with obesity: A feasibility study

Author

Giovanelli, Luca, primary, Calcaterra, Valeria, additional, Bernardelli, Giuseppina, additional, Malacarne, Mara, additional, Vandoni, Matteo, additional, Mannarino, Savina, additional, Pellino, Vittoria Carnevale, additional, Larizza, Cristiana, additional, Pagani, Massimo, additional, Zuccotti, Gianvincenzo, additional, and Lucini, Daniela, additional

Published
2023
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12. Effects of Endurance Exercise Intensities on Autonomic and Metabolic Controls in Children with Obesity: A Feasibility Study Employing Online Exercise Training

Author

Calcaterra, Valeria, primary, Bernardelli, Giuseppina, additional, Malacarne, Mara, additional, Vandoni, Matteo, additional, Mannarino, Savina, additional, Pellino, Vittoria Carnevale, additional, Larizza, Cristiana, additional, Pagani, Massimo, additional, Zuccotti, Gianvincenzo, additional, and Lucini, Daniela, additional

Published
2023
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13. Benefits in Cardiac Function from a Remote Exercise Program in Children with Obesity

Author

Mannarino, Savina, primary, Santacesaria, Sara, additional, Raso, Irene, additional, Garbin, Massimo, additional, Pipolo, Andreana, additional, Ghiglia, Silvia, additional, Tarallo, Gabriele, additional, De Silvestri, Annalisa, additional, Vandoni, Matteo, additional, Lucini, Daniela, additional, Carnevale Pellino, Vittoria, additional, Bernardelli, Giuseppina, additional, Gatti, Alessandro, additional, Rossi, Virginia, additional, Calcaterra, Valeria, additional, and Zuccotti, Gianvincenzo, additional

Published
2023
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15. Psychological Intervention Based on Mental Relaxation to Manage Stress in Female Junior Elite Soccer Team: Improvement in Cardiac Autonomic Control, Perception of Stress and Overall Health

Author

Pagani, Eleonora, primary, Gavazzoni, Naomi, additional, Bernardelli, Giuseppina, additional, Malacarne, Mara, additional, Solaro, Nadia, additional, Giusti, Emanuele, additional, Castelnuovo, Gianluca, additional, Volpi, Piero, additional, Carimati, Giulia, additional, and Lucini, Daniela, additional

Published
2023
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16. Transfer Function Gain Between Heart Period and QT Interval Variability Decreases at a 10-year Follow-up in Half-Marathon Runners

Author

De Maria, "Beatrice, primary, Bari, Vlasta, additional, Cairo, Beatrice, additional, Gelpi, Francesca, additional, Lucini, Daniela, additional, Pagani, Massimo, additional, Malacarne, Mara, additional, Maria Catai, Aparecida, additional, de Oliveira Gois, Mariana, additional, Perego, Francesca, additional, Adelaide Dalla Vecchia, Laura, additional, and Porta", Alberto, additional

Published
2022
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19. Progressive Additive Benefits of Prehabilitation and Subsequent Bariatric Surgery on Cardiac Autonomic Regulation as Assessed by Means of a Simple Unitary Composite Index: Preliminary Data from an Observational Study

Author

Giovanelli, Luca, primary, Palombo, Carlo, additional, Pina, Matteo, additional, Facchetti, Simone, additional, Malacarne, Mara, additional, Pagani, Massimo, additional, Nannipieri, Monica, additional, Berta, Rossana, additional, and Lucini, Daniela, additional

Published
2022
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20. Effects of an Online Supervised Exercise Training in Children with Obesity during the COVID-19 Pandemic

Author

Vandoni, Matteo, primary, Carnevale Pellino, Vittoria, additional, Gatti, Alessandro, additional, Lucini, Daniela, additional, Mannarino, Savina, additional, Larizza, Cristiana, additional, Rossi, Virginia, additional, Tranfaglia, Valeria, additional, Pirazzi, Agnese, additional, Biino, Valentina, additional, Zuccotti, Gianvincenzo, additional, and Calcaterra, Valeria, additional

Published
2022
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29. Left ventricular hypertrophy in world class elite athletes is associated with signs of improved cardiac autonomic regulation

Author

Oggionni, Gianluigi, Spataro, Antonio, Pelliccia, Antonio, Malacarne, Mara, Pagani, Massimo, and Lucini, Daniela

Abstract

Aim In this study we sought to assess whether in elite athletes the physiological increase in cardiac mass attending severe long-term training leading to athlete's heart is accompanied by an improvement of autonomic performance, as assessed by post exercise vagal indices and a novel unitary Autonomic Nervous System Index for sports (ANSIs).Methods The study involved 500 elite athletes (23.9 ± 6.4 years) participating in a screening organised by the National Italian Olympic Committee. All subjects underwent a complete medical examination, rest and stand autonomic assessment (heart rate variability) as well as bicycle exercise. ANSIs was also derived as radar plot from rest, stand and heart rate recovery individual proxies of autonomic nervous system regulation. All subjects were grouped into those with left ventricular hypertrophy present (LVH(+)), or not (LVH(–)), according to recognised thresholds.Results We observed that LVH(+) athletes (24.8%) showed a marked increase of post-exercise vagal indices (p< 0.001) and of ANSIs (p< 0.001), while no difference was observed for heart-rate variability indices. These changes were contingent upon sport intensity categories.Conclusions Elite athletes with physiological cardiac hypertrophy (LVH(+)) present a selective profile of indices of autonomic nervous system performance, characterised by increases of markers of vagal recovery and of the novel unitary autonomic index for sports while RR variance and spectral indices seem to be unmodified. Athlete's heart may be characterised by a specific combination of anatomical and neurocardiac remodeling. This approach might furnish potential warning signs differentiating normal training induced physiology from pathological adaptation.

Published
2024
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30. Lifestyle intervention in workers with obesity and sedentary behavior: A pilot study for the “OTTiMo LavorO” project.

Author

Bernardelli, Giuseppina, Gori, Francesca, Kolleshi, Rezarta, Tomaino, Laura, Di Maggio, Antonella, Piontini, Alessandra, Ingenito, Maria Rosaria, Lucini, Daniela, De Gennaro Colonna, Vito, and Vigna, Luisella

Subjects
*SEDENTARY behavior, *WEIGHT loss, *MEDITERRANEAN diet, *OBESITY, *LOW-calorie diet, *PILOT projects
Abstract

Workplace barriers to physical activity (PA) and sedentary work contribute to obesity. Workplace lifestyle interventions are needed to reduce sedentary behavior.The study evaluates the effects of a self-monitoring PA protocol plus diet on general health of workers with obesity.Thirty-nine workers affected by obesity were enrolled in this pilot intervention study. Monthly and daily PA diary, six-minute walking test (6MWT), Short Form-36 health survey (SF-36), and Global Physical Activity Questionnaire (GPAQ) results were evaluated prior (T0) and at the end of the study (T1). A personalized low-calorie diet based on the Mediterranean diet model was also implemented. Participants followed the protocol from one to three months depending on the date of recruitment.Significant improvements in SF36 and GPAQ scores were recorded, along with reductions in sedentary activity, weight, and BMI (p < 0.001). 6MWT significantly increased from 462.5 [412.5–500] m at T0 to 500 [462.5–550] m at T1 (p < 0.001). A multiple linear regression analysis to investigate the impact of selected covariates (PA, body weight reduction, and sedentary time) on the 6MWT was significant in men.PA self-monitoring protocols and diets are effective and sustainable for workplace interventions. PA should be part of daily medical practice and occupational physicians should encourage behavioral changes in workers. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Effects of Spinal Cord Injury Site on Cardiac Autonomic Regulation: Insight from Analysis of Cardiovascular Beat by Beat Variability during Sleep and Orthostatic Challenge

Author

Pietro Guaraldi, Mara Malacarne, Giorgio Barletta, Giuseppe De Scisciolo, Massimo Pagani, Pietro Cortelli, Daniela Lucini, Guaraldi, Pietro, Malacarne, Mara, Barletta, Giorgio, Scisciolo, Giuseppe De, Pagani, Massimo, Cortelli, Pietro, and Lucini, Daniela

Subjects
Histology, Rheumatology, spectral analysi, autonomic nervous system, sleep stage, Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine, sympathetic parasympathetic feedback, Anatomy, spinal cord injury site, spectral analysis
Abstract

Purpose: The goal of this study on Spinal Cord Injury (SCI) patients with cervical or thoracic lesion was to assess whether disturbances of ANS control, according to location, might differently affect vagal and sympatho-vagal markers during sleep and orthostatic challenge. We analyzed with linear and nonlinear techniques beat-by-beat RR and arterial pressure (and respiration) variability signals, extracted from a polysomnographic study and a rest–tilt test. We considered spontaneous or induced sympathetic excitation, as obtained shifting from non-REM to REM sleep or from rest to passive tilt. We obtained evidence of ANS cardiac (dys)regulation, of greater importance for gradually proximal location (i.e., cervical) SCI, compatible with a progressive loss of modulatory role of sympathetic afferents to the spinal cord. Furthermore, in accordance with the dual, vagal and sympathetic bidirectional innervation, the results suggest that vagally mediated negative feedback baroreflexes were substantially maintained in all cases. Conversely, the LF and HF balance (expressed specifically by normalized units) appeared to be negatively affected by SCI, particularly in the case of cervical lesion (group p = 0.006, interaction p = 0.011). Multivariate analysis of cardiovascular variability may be a convenient technique to assess autonomic responsiveness and alteration of functionality in patients with SCI addressing selectively vagal or sympathetic alterations and injury location. This contention requires confirmatory studies with a larger population.

Published
2022

32. Tailored exercise programmes for fibromyalgia: a clinical practical guide.

Author

Lucini D, Giovanelli L, Bazzichi L, Bernardelli G, Pellegrino G, Filippou G, and Sarzi Puttini P

Subjects
Humans, Treatment Outcome, Fibromyalgia therapy, Fibromyalgia physiopathology, Fibromyalgia rehabilitation, Fibromyalgia psychology, Fibromyalgia diagnosis, Exercise Therapy methods, Quality of Life
Abstract

Objectives: To evaluate the role of exercise in the management of fibromyalgia syndrome (FM) by addressing its complex pathogenesis involving central sensitisation, autonomic dysfunction, inflammation, and neurological irregularities, and examining how exercise impacts symptom exacerbation caused by external stressors and comorbid conditions., Methods: This review synthesises evidence from current literature focusing on the benefits of structured and personalised exercise programmes in FM management. It discusses the importance of specifying exercise type, intensity, frequency, duration, and progression tailored to individual patient needs and clinical objectives., Results: Regular physical activity effectively mitigates core aetiopathogenetic mechanisms of FM and improves associated conditions such as stress and obesity. It also provides benefits for preventing other chronic diseases, enhancing well-being, and promoting healthy ageing. Structured and personalised exercise programmes that start with a low-demand protocol and gradually increase exercise volume are most beneficial, by improving patient compliance and reducing the risk of adverse effects., Conclusions: Effective management of FM requires a patient-centred approach integrating both pharmacological and non-pharmacological treatments, with exercise playing a pivotal role. Personalised exercise prescriptions that consider FM patients' specific needs and limitations are crucial for optimising treatment outcomes and enhancing quality of life.

Published
2024
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