1. Segmentation of Prefrontal Lobe Based on Improved Clustering Algorithm in Patients with Diabetes.
- Author
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Zhao N, Zhao Q, Wang L, Wu X, Zhang R, and Feng H
- Subjects
- Aged, Aged, 80 and over, Anesthesia, Intravenous adverse effects, Cluster Analysis, Computational Biology, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 psychology, Female, Humans, Image Interpretation, Computer-Assisted methods, Image Interpretation, Computer-Assisted statistics & numerical data, Imaging, Three-Dimensional statistics & numerical data, Magnetic Resonance Imaging statistics & numerical data, Male, Middle Aged, Neuroimaging statistics & numerical data, Neuropsychological Tests, Postoperative Cognitive Complications etiology, Postoperative Cognitive Complications psychology, Preoperative Period, Algorithms, Diabetes Mellitus, Type 2 diagnostic imaging, Postoperative Cognitive Complications diagnostic imaging, Prefrontal Cortex diagnostic imaging
- Abstract
Diabetics are prone to postoperative cognitive dysfunction (POCD). The occurrence may be related to the damage of the prefrontal lobe. In this study, the prefrontal lobe was segmented based on an improved clustering algorithm in patients with diabetes, in order to evaluate the relationship between prefrontal lobe volume and COPD. In this study, a total of 48 diabetics who underwent selective noncardiac surgery were selected. Preoperative magnetic resonance imaging (MRI) images of the patients were segmented based on the improved clustering algorithm, and their prefrontal volume was measured. The correlation between the volume of the prefrontal lobe and Z -score or blood glucose was analyzed. Qualitative analysis shows that the gray matter, white matter, and cerebrospinal fluid based on the improved clustering algorithm were easy to distinguish. Quantitative evaluation results show that the proposed segmentation algorithm can obtain the optimal Jaccard coefficient and the least average segmentation time. There was a negative correlation between the volume of the prefrontal lobe and the Z -score. The cut-off value of prefrontal lobe volume for predicting POCD was <179.8, with the high specificity. There was a negative correlation between blood glucose and volume of the prefrontal lobe. From the results, we concluded that the segmentation of the prefrontal lobe based on an improved clustering algorithm before operation may predict the occurrence of POCD in diabetics., Competing Interests: All authors declare no conflicts of interest in this paper., (Copyright © 2021 Na Zhao et al.)
- Published
- 2021
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