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Anxiety has been widely prevalent among female Ph.D. candidates. There is a positive correlation between exercise and mental health promotion. Nevertheless, little is known about the use of fitness dance and funny running to intervene in the anxiety of female Ph.D. candidates. In this paper, the effects of fitness dance and funny running on the anxiety of female Ph.D. candidates were evaluated by a repeated measurement experimental design. We randomly divided the participants into two groups, one group received a fitness dance exercise, and the other received a funny running exercise. The Spielberger State–Trait Anxiety Inventory was used to investigate the female Ph.D. candidates' anxiety. Repeated measures ANOVA was used to test the effects of a fitness dance group and a funny running group on participants' anxiety, and to compare the differences between the two groups. Results showed that a 12-week fitness dance and funny running can alleviate participants' anxiety from severe to moderate. Specifically, fitness dance increased the positive emotional experience of participants' state anxiety (p = 0.018) and trait anxiety (p = 0.019) at 8-week, and decreased the negative emotional experience of state anxiety (p = 0.012), trait anxiety (p = 0.008), state anxiety level (p = 0.001) and trait anxiety level (p = 0.034) at 12-week. Funny running increased the positive emotional experience of participants' state anxiety (p = 0.014), and trait anxiety (p = 0.002), and reduced the negative emotional experience of state anxiety (p = 0.043), state anxiety level (p = 0.047) and trait anxiety level (p = 0.022) at 12-week. This study suggests that fitness dance and funny running are healthy behaviors, which can help Chinese female Ph.D. candidates to dissociate from anxiety and stress situations and develop a healthy lifestyle. It is worth noting that the effects of fitness dance on Chinese female Ph.D. candidates' anxiety are better than that of funny running. Based on the good effects of fitness dance in alleviating the anxiety of Chinese female Ph.D. candidates, future researches can design fitness dance intervention programs combining exercise therapy and psychotherapy according to the anxiety characteristics of female Ph.D. candidates, such as mindfulness fitness dance programs. [ABSTRACT FROM AUTHOR]

Given that stress leads to more anxiety among female Ph.D. candidates, more attention should be paid to their healthy lifestyle options. Several studies have shown that there is a negative correlation between sports and anxiety. This study took female Chinese Ph.D. candidates' anxiety and sports participation as the research objects. A questionnaire entitled "Investigation on anxiety and sports of Ph.D. candidates" was used to explore the characteristics of anxiety in female Chinese Ph.D. candidates and to investigate the association between anxiety and sports in female Chinese Ph.D. candidates. A total of 588 Ph.D. candidates participated in the questionnaire survey. Some 21 invalid questionnaires were eliminated through the standard deviation of the items of the scale, and 567 valid questionnaires were finally obtained. The questionnaire survey was conducted online from 26 February to 15 March 2022, using the convenience sampling method. The results show that the anxiety level of female Chinese Ph.D. candidates is higher than that of male Ph.D. candidates and that the anxiety level of female Ph.D. candidates in a non-sports discipline is the highest. Weekly sports participation significantly lowers female Ph.D. candidates' anxiety level (p < 0.01). Physical fatigue caused by study and work hinders female Ph.D. candidates from participating in sports (p < 0.05). Some female Chinese Ph.D. candidates in a negative emotional state are unwilling to participate in sports (p < 0.01). Future research should formulate different types of sports intervention programs suitable for alleviating the anxiety of female Ph.D. candidates. [ABSTRACT FROM AUTHOR]

Opioid withdrawal generates extremely unpleasant physical symptoms and negative affective states. A rapid relief of opioid withdrawal-induced anxiety has obvious clinical relevance but has been rarely reported. We have shown that injection of ketamine metabolite (2 R ,6 R)-hydroxynorketamine (HNK) leads to a rapid alleviation of anxiety-like behaviors in male mice undergoing chronic morphine withdrawal. Here we investigated the contribution of nucleus accumbens shell (sNAc) parvalbumin (PV)-neurons to this process. Chronic morphine withdrawal was associated with higher intrinsic excitability of sNAc PV-neurons via reduced voltage-dependent potassium currents. Chemogenetic inhibition of sNAc PV-neurons reversed the enhanced excitability of PV-neurons and anxiety-like behaviors in these morphine withdrawal male mice, while activation of sNAc PV-neurons induced anxiety-like behaviors in naive male mice. (2 R ,6 R)-HNK reversed the altered potassium currents and intrinsic excitability of sNAc PV-neurons. Our findings demonstrate an important contribution of sNAc PV-neurons to modulating morphine withdrawal-induced anxiety-like behaviors and rapid relief of anxiety-like behaviors by (2 R ,6 R)-HNK, this newly identified target may have therapeutic potentials in treating opioid addiction and anxiety disorders. • sNAc PV-neuron excitability is higher in mice undergoing morphine withdrawal. • Inhibiting sNAc PV-neurons improves morphine withdrawal-induced anxiety-like behaviors. • Activating sNAc PV-neurons elicits anxiety-like behaviors in naïve mice. • (2 R ,6 R)-HNK alleviates morphine withdrawal-induced anxiety-like behaviors in mice. • (2 R ,6 R)-HNK increases K+ currents and reduces excitability of sNAc PV-neurons. [ABSTRACT FROM AUTHOR]