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Cytomegalovirus infection is the most prevalent cause of congenital and acquired sensorineural hearing loss, and it can be classified as symptomatic or asymptomatic at birth, and symptomatic individuals have a higher risk of developing neurological sequelae (1). In Brazil, the screening for cytomegalovirus infection in pregnant women is not part of the prenatal routine, making the possible diagnosis of congenital cytomegalovirus difficult (2). Considering the importance of this topic in the field of public policies for women and children's health and the few studies in Brazil, it is necessary to develop other studies and reports associating congenital cytomegalovirus infection and sensorineural hearing loss. The purpose of this case report is to highlight the influence of congenital cytomegalovirus infection and its impact on sensorineural hearing loss, stressing the importance of early diagnosis and intervention, besides demonstrating how socioeconomic factors affect the scope of contamination and transmission. This paper consists of the description of a case report of congenital infection that occurred in a private hospital in the city of Sorocaba/SP, through the report of the mother and the results of tests performed. The case report highlights the difficulty in establishing early diagnosis of neonatal cytomegalovirus, which represents an obstacle to a better prognosis. It is worth stressing that early diagnosis and intervention are of paramount importance, through Universal Newborn Hearing Screening, as well as audiological follow-up and monitoring. [ABSTRACT FROM AUTHOR]