1. Single-cell DNA methylation and 3D genome architecture in the human brain.
- Author
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Wei Tian, Jingtian Zhou, Bartlett, Anna, Qiurui Zeng, Hanqing Liu, Castanon, Rosa G., Kenworthy, Mia, Altshul, Jordan, Valadon, Cynthia, Aldridge, Andrew, Nery, Joseph R., Huaming Chen, Jiaying Xu, Johnson, Nicholas D., Lucero, Jacinta, Osteen, Julia K., Emerson, Nora, Rink, Jon, Lee, Jasper, and Li, Yang E.
- Subjects
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DNA methylation , *HUMAN genome , *GENE expression , *GENETIC regulation , *REGIONAL disparities - Abstract
The article discusses a study on single-cell DNA methylation and 3D genome architecture in the human brain. The research provides a comprehensive atlas of epigenomic characteristics, revealing cell-type specificity, chromatin structures, and DNA methylation patterns, which will be valuable for understanding brain cell diversity, gene regulation mechanisms, and the development of genetic tools.
- Published
- 2023
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