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As a project construction organization model, whole-process engineering consulting (WPEC) is currently being promoted in China's engineering consulting industry. However, various factors create numerous obstacles that hinder this model's effective promotion and application. One essential task is to deeply analyze the transmission mechanism of the influencing factors in the promotion and application of WPEC, and explore effective pathways for promoting and applying this model. This paper systematically organizes and summarizes 10 primary influencing factors and 38 secondary influencing factors for promoting WPEC. Using the complex network analysis method, a network of influencing factors for promoting WPEC, a network structure, and motif analyses are conducted. The results show that the influencing factors have a complex transmission mechanism, and complex network analysis can reveal the laws of their construction and their causes. This paper provides a systematic basis and theoretical support for the effective formulation of policies related to the promotion and application of WPEC. [ABSTRACT FROM AUTHOR]

The Tephritidae family causes damage to fruits in tropical and subtropical regions around the world, with Bactrocera minax Enderlein (Diptera: Tephritidae) widely distributed in China, causing severe economic damage to Chinese citrus. Currently, preventing the rapid spread of B. minax remains an effective strategy to control it as the climate continues to warm in the future. In this context, it is crucial to understand the potential geographic range of B. minax under climate change. We used meta-analysis to assess the survival of Tephritidae insects under temperature stress. We also used the maximum entropy (MaxEnt) model to predict the suitable regions and migration trajectories of B. minax in China under current and future climatic conditions. Through comprehensive analysis of the experimental data, we found that the survival rate of Tephritidae insects in the suitable temperature range showed an increasing trend with the increase in warming extent. Using the MaxEnt model, we observed that the highly suitable area, as well as the moderately suitable area of B. minax , were expanding in all 3 future climate scenarios, with the distribution moving toward the high latitude region and the coastal region of China. Our results also indicate that temperature and precipitation contribute more to the model in the current year. Combining multiexperiment data, our study demonstrates that the potential distribution of B. minax in China will expand under future climate warming scenarios, and these predictions will provide important information for monitoring B. minax and informing managers in developing control strategies. [ABSTRACT FROM AUTHOR]

A new gridded spatio-temporal big data fusion method is proposed for the organization and management of cropland big data, which could serve the analysis application of cropland quality evaluation and other analyses of geographic big data. Compared with traditional big data fusion methods, this method maps the spatio-temporal and attribute features of multi-source data to grid cells in order to achieve the structural unity and orderly organization of spatio-temporal big data with format differences, semantic ambiguities, and different coordinate projections. Firstly, this paper constructs a dissected cropland big data fusion model and completes the design of a conceptual model and logic model, constructs a cropland data organization model based on DGGS (discrete global grid system) and Hash coding, and realizes the unified management of vector data, raster data and text data by using multilevel grids. Secondly, this paper researches the evaluation methods of grid-scale adaptability, and generates distributed multilevel grid datasets to meet the needs of cropland area quality evaluation. Finally, typical data such as soil organic matter data, road network data, cropland area data, and statistic data in Da'an County, China, were selected to carry out the experiment. The experiment verifies that the method could not only realize the unified organization and efficient management of cultivated land big data with multimodal characteristics, but also support the evaluation of cropland quality. [ABSTRACT FROM AUTHOR]

Given the rising popularity of post-retirement work and its potential benefits for older adults' mental health, this study examined older adults' adaptation ability as a conditional factor for the impact of post-retirement work on depression. Quantitative data from 1433 working older adults and 1433 non-working older adults were analyzed using the PROCESS macro in SPSS to test a moderated regression model with adaptation ability as the moderator. Results showed that older adults with lower adaptation ability demonstrated significantly lower depression if they worked (vs. did not work). Older adults with higher adaptation ability exhibited significantly higher depression if they worked (vs. did not work). These findings were subsequently verified with a robustness check. Overall, post-retirement work did not prevent depression for the entire sample; working only alleviated depression among older adults with limited adaptation ability. Older adults with stronger adaptation ability could better maintain their mental health by staying retired. This study fills a knowledge gap regarding the relationship between post-retirement work and mental health. Implications for aging societies are also discussed. [ABSTRACT FROM AUTHOR]

The city region has emerged as an important form of regional development and governance. However, the dynamics of spatial inequality in city regions are misunderstood. This study examines the Yangtze River Delta (YRD) to determine the spatiotemporal evolution of regional inequality across prefecture-level municipalities from 1990 to 2018. It finds that regional inequality has steadily increased since the 1990s but has declined somewhat in recent years. This is associated with faster growth and higher upward mobility of central regions in the early reform period and increases in the upward mobility of the periphery in recent years. The gradient-distance curve of the Shanghai-centered economy sharpened and then flattened, indicating the polarization of growth in the core regions, followed by the diffusion of development and improved regional integration. However, the core-periphery remains stronger within provinces between provincial capitals and other regions. Despite regional integration and peripheral development, the problem of spatial exclusion and core-periphery structures persists. More attention needs to be given to the core-periphery relationship and the development of peripheral regions to promote regional integration and reduce spatial polarization. [ABSTRACT FROM AUTHOR]

The Huashandong W deposit (7.7 Mt @ 0.26% WO3) is a newly discovered Neoproterozoic scheelite-dominated deposit in the world-class Jiangnan tungsten belt, South China. It occurs largely in metasedimentary rocks near the western margin of the Neoproterozoic Jiuling batholith and mainly consists of W-bearing exogreisen, hydrothermal breccias, and quartz veins. Two episodes of Neoproterozoic granite magmatism are identified with zircon U-Pb ages of ca. 830–823 and 807–804 Ma, respectively. According to cross-cutting relationships and mineral assemblages, two periods of hydrothermal alteration and W mineralization, corresponding to the two episodes of granite magmatism, are recognized in the Huashandong deposit. The early period is dominated by greisenization and associated scheelite mineralization whereas the late period is characterized by sericitization, hydrothermal brecciation, quartz veining, and associated scheelite and minor wolframite mineralization. Molybdenite Re-Os dating indicates that the early- and late-period W mineralization took place at ca. 828 and 800 Ma, respectively. Zircon trace element characteristics suggest that the Jiuling granite crystallized from reduced granitic magmas and has the potential for W mineralization. The petrologic and geochemical features of the Jiuling granite, coupled with the zircon U-Pb ages and Hf isotopic signatures and molybdenite Re-Os ages, imply that the Huashandong W deposit is genetically related to two phases of evolved granodiorites in the Jiuling batholith. The magmatic-hydrothermal nature of both metallogenic events is confirmed by H-O isotopes on hydrothermal quartz. [ABSTRACT FROM AUTHOR]

Female college students are more likely to have a strong stress response to the COVID-19 pandemic, which seriously affects their health and merits greater attention. The present study is a randomized controlled trial carried out during the COVID-19 pandemic. The purpose of this study was to explore whether a yoga intervention could have a positive impact on balance and flexibility and be the primary form of home exercise for female college students in China. Forty female college students were randomly selected for the study. After 16 weeks of yoga intervention, the ability of the yoga group to balance on one leg improved by 5.35 seconds (using the single-limb stance test) and 5.7 seconds (using the Romberg test). The flexibility of the lower back and legs increased by 3.5 cm (using the sit and reach test), and the flexibility of the groin and hip increased by 6 cm (using the Splits test). The balance ability and flexibility of the control group before and after the experiment were not significantly different (p>0.05). These results suggest that during the COVID-19 outbreak when access to public facilities was limited, a yoga intervention could have a positive impact on health and be the main form of home exercise for female college students. Schools and government departments could design online yoga classes to encourage individuals to actively participate in yoga to stay healthy. [ABSTRACT FROM AUTHOR]

Acculturation and identity are two significant determinants of the psychological well‐being of migrants, but how they interactively affect psychological well‐being is still underexplored. This study proposes an interactional perspective that links acculturation and urban identity to the psychological well‐being of rural–urban migrants in China. Using data from the 2014 National Migrant Population Dynamic Monitoring Survey, the results of multilevel modeling indicate that both acculturation and urban identity significantly affect the psychological well‐being of rural–urban migrants. Migrants who adopt the integration and assimilation strategy show better psychological well‐being than those who adopt the separation and marginalization strategy. Rural–urban migrants who have a stronger sense of urban identity show better psychological well‐being than those with a weaker sense of urban identity. Meanwhile, urban identity and acculturation also interactively affect the psychological well‐being of rural–urban migrants. In particular, urban identity alleviates the negative pressure generated in the process of acculturation for those who adopt the acculturation strategy of separation. In addition, the effect of acculturation and urban identity on the psychological well‐being of rural–urban migrants varies by migration distance. The research contributes to the literature by demonstrating that cultural identity and place identity interactively affect the psychological well‐being of internal migrants. [ABSTRACT FROM AUTHOR]

Background: Sedative gastrointestinal endoscopy is extensively used worldwide. An appropriate degree of sedation leads to more acceptability and satisfaction. Artificial intelligence has rapidly developed in the field of digestive endoscopy in recent years and we have constructed a mature computer-aided diagnosis (CAD) system. This system can identify the remaining parts to be examined in real-time endoscopic procedures, which may help anesthetists use anesthetics properly to keep patients in an appropriate degree of sedation. Aims: This study aimed to evaluate the effects of the CAD system on anesthesia quality control during gastrointestinal endoscopy. Methods: We recruited 154 consecutive patients at Renmin Hospital of Wuhan University, including 76 patients in the CAD group and 78 in the control group. Anesthetists in the CAD group were able to see the CAD system's indications, while anesthetists in the control group could not. The primary outcomes included emergence time (from examination completion to spontaneous eye opening when doctors called the patients' names), recovery time (from examination completion to achievement of the primary recovery endpoints) and patient satisfaction scores. The secondary outcomes included anesthesia induction time (from sedative administration to successful sedation), procedure time (from scope insertion to scope withdrawal), total dose of propofol, vital signs, etc. This trial was registered in the Primary Registries of the WHO Registry Network, with registration number ChiCTR2100042621. Results: Emergence time in the CAD group was significantly shorter than that in the control group (p < 0.01). The recovery time was also significantly shorter in the CAD group (p < 0.01). Patients in the CAD group were significantly more satisfied with their sedation than those in control group (p < 0.01). Vital signs were stable during the examinations in both groups. Propofol doses during the examinations were comparable between the two groups. Conclusion: This CAD system possesses great potential for anesthesia quality control. It can improve patient satisfaction during endoscopic examinations with sedation. Trial registration: ChiCTR2100042621. [ABSTRACT FROM AUTHOR]

The acculturation of domestic migrants has rarely been explored. Drawing on the bi-dimensional theory of acculturation, this study examined the strategies and determinants of urban acculturation among rural–urban migrants in China. Using data from a large survey project, we conducted latent class analysis (LCA), K-means clustering analysis, and midpoint scores analysis. Our findings suggested that the acculturation strategies of rural–urban migrants generally conform to Berry's framework, with integration, assimilation, and separation as the dominant patterns. However, we identified a moderate integration pattern, instead of the marginalization pattern, through the application of LCA and K-means clustering analysis. Additionally, the acculturation strategies identified using the three methods exhibited a moderate degree of consistency. Furthermore, socioeconomic status, language usage, cultural differences, and social interaction play a significant role in shaping the acculturation of rural–urban migrants in cities. This study demonstrates that the acculturation of rural–urban migrants in host cities shares certain similarities with that of international migrants. However, it is also important to note the unique characteristics of rural–urban migrants. [ABSTRACT FROM AUTHOR]

Most existing studies on shrinking cities focus on identifying and characterizing population contraction at the city scale and lack an in-depth exploration of the mechanisms of population contraction and daily life scenarios at the street scale. To fill this gap, this study employed semi-structured interviews and participant observation to analyze the street vitality and mechanisms of operation of Dongda Street in Rugao County of Jiangsu Province in China. The study found the following. First, the interspersed urban renewal has allowed residents to retain their original lifestyles and time-space routines, and they continue to enact an endogenous street ballet. Second, new residents gradually develop new lifestyles and time-space routines in the streets, showcasing an exogenous street ballet. Third, both groups jointly perform hybrid street ballets in their daily lives through close public interactions. These findings suggest that while Dongda Street is an aging neighborhood, the survival of the original street pattern and old buildings has allowed the neighborhood to retain its historical flavor. Additionally, the moving in of creative industries and merchants injects new vitality into the neighborhood. These findings examine daily street life in the context of population contraction and help break the stereotypes of population contraction. • The interspersed urban renewal has allowed local residents to retain their original endogenous street ballet. • New residents gradually develop time-space routines in the streets, showcasing an exogenous street ballet. • Both groups jointly perform hybrid street ballets in their daily lives through close public interactions. [ABSTRACT FROM AUTHOR]

Inorganic phosphate (Pi) is taken up by plant roots and translocated via phosphate transporters. Previously, we showed that phosphate transporter OsPHT1;4 in the PHT1 family participates in phosphate acquisition and mobilization; it facilitates the embryo development of Japonica rice Nipponbare. This study investigated the potential of manipulating the expression of OsPHT1;4 to increase Pi acquisition efficiency and crop productivity in rice cv. Wuyunjing 7 (WYJ 7), a cultivar widely grown in Yangtze River Delta of China. The OsPHT1;4 overexpression lines and wild-type WYJ 7 were treated under different Pi conditions in hydroponic and field experiments. Quantitative real-time RT-PCR analysis and the transgenic plants expressing GUS reporter gene indicate strong expression of OsPHT1;4 in roots and leaf collars of cv. WYJ 7. The total P contents in shoots of the OsPHT1;4-overexpressing plants were significantly higher under Pi-deficient hydroponic conditions than the wild type under Pi sufficiency and deficiency. 33Pi uptake and translocation assays confirmed the results. In the field condition, OsPHT1;4 overexpression lines had a higher P concentration in tissues than the wild type control, and the panicle performance of the overexpression lines including the grain yield was improved as well. Taken together, our results show that OsPHT1;4 plays an important role in the acquisition and mobilization of Pi in WYJ 7, especially under Pi deficiency. The study highlights the importance of OsPHT1;4 in improving the agronomic traits of the widely grown rice cultivar in China. [ABSTRACT FROM AUTHOR]

The increasing population mobility in the context of globalization has greatly reshaped people's cognition and sentiment toward their places of residence. China has witnessed an unprecedented surge in internal migration from rural to urban areas since the mid-1980 s. However, limited by multiple barriers, rural-urban migrants in China face predicaments in establishing a psychological bond with their host cities. This study develops a conceptual framework that links rural-urban migrants' urban experiences and attitudes toward both original and urban lifestyles to their city attachment. Using a nationwide survey and structural equation modeling, this study finds that (1) while willingness of social interaction with urban locals has a positive effect on the urban attachment of rural-urban migrants, perceived social exclusion depresses the urban attachment of rural-urban migrants. (2) Loyalty to one's original lifestyle is not significantly associated with the urban attachment of rural-urban migrants, whereas preference for the urban lifestyle is positively associated with the urban attachment of rural-urban migrants. (3) Willingness of social interaction with urban locals and perceived social exclusion can affect the urban attachment of rural-urban migrants by influencing their attitudes toward the urban lifestyle. (4) perceived social exclusion is positively related to loyalty to the original lifestyle for rural-urban migrants from cities located in northern area of China, while it is negatively related to loyalty to the original lifestyle for rural-urban migrants from cities located in the central and southern areas. Our study broadens the research on the urban attachment of rural-urban migrants and suggests that migrants' experiences in the host society and attitudes toward the lifestyle of the host society are significant in shaping their place attachment to the host society. Furthermore, the process by which rural-urban migrants form meaningful relations with the city can occur through the influence of urban experiences on attitudes toward the urban lifestyle. [ABSTRACT FROM AUTHOR]

Accurate and reliable monthly runoff forecasting plays an important role in making full use of water resources. In recent years, long short-term memory neural networks (LSTM), as a deep learning technology, has been successfully applied in forecasting monthly runoff. However, the hyperparameters of LSTM are predetermined, which has a significant influence on model performance. In this study, given that the decomposition of monthly runoff series may provide a more accurate prediction, as revealed by many previous studies, a hybrid model, namely, VMD-GWO-LSTM, is proposed for monthly runoff forecasting. The proposed hybrid model comprises two main components, namely, variational mode decomposition (VMD) coupled with the gray wolf optimizer (GWO)-based LSTM. First, VMD is utilized to decompose raw monthly runoff series into several subsequences. Second, GWO is implemented to optimize the hyperparameters of the LSTM for each subsequence on the condition that the inputs are determined. Finally, the total output of all subsequences is aggregated as the final forecast result. Four quantitative indices are employed to evaluate the model performance. The proposed model is demonstrated using 73 and 62 years of monthly runoff series data derived from the Xinfengjiang and Guangzhao Reservoirs in China's Pearl River system, respectively. To identify the feasibility and superiority of the proposed model, backpropagation neural networks (BPNN), support vector machine (SVM), LSTM, EMD-LSTM, VMD-LSTM and GWO-LSTM are also utilized for comparison. The results indicate that the proposed hybrid model can yield best forecast accuracy among these models, making it a promising new method for monthly runoff forecasting. [ABSTRACT FROM AUTHOR]

After decades of rapid economic growth and massive rural-to-urban migration, rural poverty in China has been largely alleviated. Existing literature has highlighted the crucial role played by non-farm employment in the rural population's escape from poverty. However, despite some engagement in non-farm employment, a huge population in rural China remains poor. Why rural households remain poor in spite of non-farm employment has not been sufficiently explored by scholars. To fill the research gap, this paper explores the underlying mechanisms of poverty among the poor rural population, based on a recent questionnaire survey (n = 2,822) conducted in rural North Jiangsu in China. Our multinomial logistic regression model and OLS regression model show that education is positively associated with the likelihood of engaging in non-farm sectors. Relatively low education attainment of working-age household members (secondary education and below) restricted the earnings from non-farm activities, reducing the likelihood of escaping poverty. Supporting higher education for their children is often a heavy burden for poor non-agricultural rural households, driving them into the poverty trap. The results also show that significant family events, such as severe illness and children's college enrollment, have kept rural households poor, even if some household members have participated in non-farm activities through migration or working in the local non-rural sector. In addition, instead of being looked after, some apparently dependent family members (the elderly) undertake agricultural activities and domestic work to support the out-migration of the labor force in poor rural households to enable household wealth accumulation. The findings suggest that policymakers should implement a series of reforms, especially regarding improvement in health insurance and education and the economic development in the local areas (incl. rural areas and nearby towns) to deal with rural poverty. • Identify features of poor rural households who choose to escape the poverty trap through non-agricultural work. • Education investment may be insufficient for escaping the poverty trap if the education of the household workforce remains low. • Dependent family members at home contribute to improving the discretionary incomes of poor rural households. • Illness and college study prohibite poor rural households from taking non-agricultural work to escape poverty. [ABSTRACT FROM AUTHOR]

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The CRF01_AE and CRF07_BC clades dominate the human immunodeficiency virus (HIV) epidemics in China. Both clades have been identified in the men who have sex with men (MSM) population in Guangdong province, raising a serious concern of possible complex recombination events ahead. Here, we report the first case of CRF01_AE/CRF07_BC recombinant sampled from a MSM patient in southern China. The genomic structure of this case is a mosaic with some regions resembling the CRF01_AE and CRF07_BC clades. Our phylogenetic analyses show that the two parental lineages of this recombinant virus were mainly found in the MSM population. This case has a different genomic composition compared with other recombinants descended from the same parental clades CRF01_AE and CRF07_BC. Our finding suggests that the MSM populations have become a hotspot for expanding viral diversity through the viral recombination mechanism. Therefore, further epidemiologic surveillance and monitoring should be conducted within the MSM populations to help advance our knowledge of viral transmission mechanisms. Additionally, these measures will serve to enhance the control and prevention of HIV/acquired immunodeficiency syndrome in China. [ABSTRACT FROM AUTHOR]

[Display omitted] • Two stages of fluid exsolution are recognized in the Weijia W skarn deposit. • F-rich magmatic fluids are enriched in REEs, Y, Nb, Ta with flat REE patterns. • F consumption is critical for the compositional evolution of F-rich mineralizing fluids. • Combined garnet and scheelite trace elements are powerful in tracking W skarn mineralization. Fluid evolution is an essential subject in the studies of hydrothermal ore-forming processes. Garnet and scheelite prevail in W-bearing skarn deposits and record plentiful information on W skarn mineralization. In-situ LA-ICP-MS trace element analyses have been carried out on the garnet and scheelite from the F-rich Weijia W deposit in South China to constrain the processes of fluid evolution and W skarn mineralization. The Weijia W deposit mainly consists of calcic and magnesian skarns and was formed through six stages of alteration and mineralization. Two stages of fluid exsolution are recognized in the magmatic-hydrothermal system. The earlier exsolved fluids are Cl-rich with rightward-sloping REE patterns and result in pre-ore skarnization. The later exsolved fluids are F-rich with relatively flat REE patterns and are responsible for W mineralization. The pre-ore garnets are LREE-enriched and HREE-depleted whereas the syn-ore garnets are LREE-depleted and HREE-enriched with lower δ Eu values than the former, denoting a transition from wall rock-controlled to magmatic fluid-dominated fluid-rock interaction. Combined with the skarn occurrences, mineral assemblages, and garnet textures, it is revealed that the mechanism of skarn formation shifts from more diffusive metasomatism under lower water/rock ratios to more advective metasomatism at higher water/rock ratios. The advective metasomatism with a high flux of ore-forming fluids is hydrodynamically favorable for the consequent W mineralization. The earliest-formed scheelite is akin to the host granite porphyry in REE patterns and can reflect the features of initial mineralizing fluids. It has high ΣREE (1255–5059 ppm), Y (616–1416 ppm), Nb (585–2629 ppm), Ta (14–248 ppm), Mn (up to 1977 ppm) and low Mo (mostly < 1000 ppm) contents, indicating that the primary F-rich magmatic fluids are reduced and enriched in REEs, Y, Nb, and Ta. The contents of ΣREE, Y, Nb, and Ta in scheelite are decreasing with the evolution of the F-rich mineralizing fluids. The latest-formed scheelites have distinctly lower ΣREE (2.9–140 ppm), Y (0.01–4.1 ppm), Nb (1.7–77 ppm), and Ta (0.04–0.19 ppm) contents and higher (La/Yb) N ratios and δ Eu values. They show 1:1 positive correlation of Eu N vs. Eu N * and have high Mo (up to 129466 ppm) and low Mn (as low as 3.4 ppm) contents, implying involvement of meteoric waters in the evolved ore-forming fluids and an oxidizing condition. Fluid-rock interaction, mineral precipitation, and fluid mixing largely control the process of fluid evolution. Fluorine consumption due to the formation of fluorite and the other F-rich minerals is vital for the compositional evolution of F-rich mineralizing fluids. The decrease of F concentration in fluids will depress the solubilities of REEs, Y, Nb, and Ta and enhance the LREE/HREE fractionation. Greisenization and skarnization induced the neutralization of the acidic W-bearing fluids and the liberation of Ca from the granite porphyry and carbonate strata and then triggered the scheelite precipitation. The carbonate strata contain abundant Ca and the granite porphyry is poor in Ca, and thus the economic W mineralization dominantly occurs in the skarns. [ABSTRACT FROM AUTHOR]

[Display omitted] • Comprehensive analysis of flavor formation of mandarin fish from smell and taste. • Nineteen key aroma compounds were identified in fermented mandarin fish. • The differential metabolites presented a significant correlation to the key volatiles. • 5′-nucleotides were reduced, whereas Asp and Glu were increased. • Tryptophan metabolism was the potential generation pathway of the fish stinky. Volatolomics and metabolomics were performed to explore the generation mechanism of the characteristic flavor of mandarin fish during fermentation. This study revealed a novel finding that umami-tasting amino acids, succinic acid, and peptides increased, while taste-presenting nucleotides decreased after fermentation. The results showed that 19 key aroma compounds were identified. The most nitrogenous compounds were produced after fermentation, the total concentration of which was >5 mg/kg. A high odor activity value of 443 was established for stinky indole. PLS-DA showed that sn -glycero-3-phosphocholine, hypoxanthine, creatine, and trimethylamine N -oxide were the key metabolites associated with the key volatiles. Umami-tasting amino acids could contribute to the characteristic taste. Metabolic pathway analysis revealed that tryptophan metabolism, trimethylamine metabolism, and monoterpenoid biosynthesis were the potential generation pathways of indole, trimethylamine, and terpenoids, respectively. Collectively, the results provide thoughts for targeted controlling the flavor of fermented mandarin fish. [ABSTRACT FROM AUTHOR]

[Display omitted] • In-field measurement of nitrite as carcinogen is important for food safety. • A fully integrated colorimetric detection system for nitrite is offered. • APP is combined with DCNN as visual monitoring platform. • Validity period of test paper is prolonged from 7 d to more than 30 d. • The accuracy of food classification is high as 91.33–100% Nitrite is one of the most common carcinogens in daily food. Its simple, rapid, inexpensive, and in-field measurement is important for food safety, based on the requirements of the standard from Codex Alimentarius Commission and China. Using polyacrylonitrile (PAN) and thin layer silica gel (SG), p-aminophenylcyclic acid (SA) and naphthalene ethylenediamine hydrochloride (NEH), as carriers and chromogenic agents, respectively, PAN-NSS as nitrite color sensor is proposed. After fixing and protecting of SA and NEH with layer-upon-layer PAN, the validity period of the test paper can be prolonged from 7 days to more than 30 days. The reproducibility of PAN-NSS preparation is ensured by electrospinning. Combined with PAN-NSS, deep convolutional neural network (DCNN) and APP as a visual monitoring platform, which has the functions of rapid sampling, data processing and transmission, intuitive feedback, etc., and provides a fully integrated detection system for field detection. [ABSTRACT FROM AUTHOR]

Chinese steamed bread (CSB) is an important staple of the Chinese people, and its flavor profile is mostly affected by wheat varieties among others. This study selected wheat flour made from three different wheat varieties and investigated their contribution to the CSB flavor profile in terms of metabolism. Thirteen aroma-active compounds identified by GC-O were determined as the main contributors to the different aroma profiles of three CSBs. 350 sensory trait-related metabolites were obtained from five key modules via weighted gene co-expression network analysis. It was found that the sensory characteristics of CSBs made of different wheat flour were significantly different. The higher abundance of lipids in Yongliang No.4 (YL04) wheat flour was converted to large number of fatty acids in fermented dough, which led to the bitterness of CSB. Besides, the abundance in organic acids and fatty acids contributed to the sour, milky, wetness and roughness attributes of YL04-CSB. More fatty amides and flavonoids in Jiangsu Red Durum wheat flour contributed to the fermented and winey attributes of CSB. Carbohydrates with higher abundance in Canadian wheat flour was involved in sugar-amine reaction and glucose conversion, which enhanced the sweetness of CSB. In addition, fatty acids, organic acids, amino acids, and glucose were crucial metabolites which can further formed into various characteristic compounds such as hexanal, hexanol, 2,3-butanediol, acetoin, and 2,3-butanedione and thus contributed to the winey, fresh sweet, and green aroma properties. This study is conductive to better understand the evolution of the compounds that affect the quality and aroma of CSBs., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Mutations in the SH3TC2 gene cause Charcot-Marie-Tooth disease type 4C (CMT4C), characterized by inherited demyelinating peripheral neuropathy. CMT4C is a common form of CMT4/autosomal recessive (AR) CMT1. This study examined the SH3TC2 variants, investigated genotype-phenotype correlations and explored the frequency of CMT4C in Chinese patients. A total of 206 unrelated patients of Chinese Han descent clinically diagnosed with CMT were recruited. All patients underwent detailed history-taking, neurological examination, laboratory workups, and electrophysiological studies. Genetic analysis was performed via high-throughput target sequencing (NGS). Three patients, one male and two females, were found to carry five SH3TC2 mutations: patient 1 (c.3154C > T, p.R1054X; c.929G > A, p.G310E); Patient 2 (c.2872&#95;2872del, p.S958fs; c.3710C > T, p.A1237V) and Patient 3 (c.2782C > T, p.Q928X; c.929G > A, p.G310E). The c.2872&#95;2872del, c.3710C > T and c.2782C > T variants were not reported before. CMT4C caused by SH3TC2 mutation is a very common type of CMT4/AR CMT1. Three novel mutations, c.2872&#95;2872del, c.3710C > T and c.2782C > T, were found in this study. Combination of clinical phenotype, nerve conduction studies, genetic analysis and bioinformatics analysis are of vital importance in patients suspected as CMT., (© 2021. Belgian Neurological Society.)