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The South China Sea (SCS) coastlines are particularly vulnerable to tsunamis due to rapid urbanization and dense infrastructures. However, whether the SCS has experienced ocean-wide tsunamis is still under debate. Some geological records from the offshore islands inside the SCS imply a regional tsunami event may have occurred approximately 1000-yr-ago. We address these questions for the first time using forward numerical simulations in the SCS: what source could be responsible for such deposits, how the deposits were formed and at what conditions do the deposits could be preserved? Here, we assume the validity of the tsunami deposit hypothesis and use the forward model COMCOT-SED to investigate if these tsunami deposits can be linked to potential seismogenic tsunami sources inside the SCS, including megathrust earthquakes (Mw8.8–9.2) from the Manila subduction zone (MSZ) and the 1918 Mw7.5 Nan'ao earthquake from the Littoral Fault Zone (LFZ) in the northern continental shelf of the SCS. We also utilize a reported tsunami deposit from Qing'ao Embayment, Nan'ao Island, China, to exemplify the deposit formation process in a typical barrier-low coastal plain system. Quantitative analysis suggests large earthquakes from the MSZ may account for the reported geological deposits. The full-rupture earthquake scenario could best explain the depositions if such extreme case is geophysically and geologically plausible. If not, earthquakes (∼ Mw 9.0) covering the northern (16–23.5°N) or southern portion (14–19°N) of the MSZ could also be suitable candidates. Such great earthquakes can generate large tsunami waves (>7 m) that inundate the Qing'ao Embayment, transporting sediments and leaving tsunami deposits in low-lying areas. Conversely, tsunamis triggered by nearshore earthquakes in the LFZ cannot cause deposition in Qing'ao Embayment. The barrier-low coastal plain system is well-suited for preserving tsunami deposits, which remain unaltered by subsequent tsunami waves. Our findings offer a quantitative reference for paleo-tsunami research in the SCS and enhance global understanding of the tsunami deposition process in barrier-low coastal plain systems. • The full-rupture earthquake (Mw 9.0) from the MSZ best explains the reported plausible tsunami deposits in the South China Sea. • Tsunami waves >7 m generated by MSZ earthquakes could inundate the Qing'ao Embayment anddeposit sediments in low-lying areas. • The barrier-low coastal plain system in Qing'ao Embayment forms favorable conditions to preserve overwash tsunami deposits. [ABSTRACT FROM AUTHOR]

Objectives: The prevention of mother‐to‐child transmission of HIV has been a global success. But little is known about the growth parameters of infants delivered by mothers with HIV or the drug resistance of infants with HIV in China. The study aimed to assess growth parameters and drug resistance in Chinese infants exposed to HIV. Methods: We conducted an 18‐month longitudinal follow‐up study of 3283 infants (3222 without HIV; 61 with HIV) born to mothers with HIV in the Guangxi Zhuang Autonomous Region between January 2015 and December 2021. The weight and length of all participants was recorded. In addition, genetic subtypes and drug resistance analysis were performed for infants with HIV. Results: Compared with infants without HIV, those with HIV had significantly lower weight/length Z‐scores, except at 18 months of age. The length/age Z‐scores of infants with HIV was significantly reduced, except at 1 month of age. The weight/age Z‐scores of infants with HIV were significantly lower at all follow‐up time points. The weight/length Z‐scores of male infants without HIV were significantly lower than for female infants without HIV at all follow‐up time points. Male infants without HIV had lower length/age and weight/age Z‐scores than female infants at the remaining follow‐up points, except at 1 month of age. Of a total of 61 infants with HIV, subtype and drug‐resistance data were obtained from 37 (60.66%) samples. Infants with HIV were dominated by the CRF01_AE genotype and showed a diversity of mutation sites dominated by non‐nucleoside reverse transcriptase inhibitor resistance. Conclusion: Our study demonstrates the growth of infants exposed to HIV in southwest China and provides detailed information on subtype distribution and drug resistance of those with HIV. Nutritional support and drug‐resistance surveillance for infants exposed to HIV need to be strengthened. [ABSTRACT FROM AUTHOR]

18th China Drying Conference & 1st Postgraduate Academic Forum in Drying Field, Luoyang, P.R. China, September 26-28, 2021 During September 26-28, 2021, the 18 SP th sp China Drying Conference & 1 SP st sp Postgraduate Academic Forum in Drying Field, hosted by the Drying Professional Group of Chemical Engineering Committee of Chinese Chemical Society, organized by Henan University of Science and Technology, and co-organized by Drying Equipment Branch of China General Machinery Industry Association, was successfully held in Luoyang, China (Figure 1). The China Drying Conference, initiated by the Drying Professional Group of Chemical Engineering Professional Committee of the Chemical Industry and Engineering Society of China in 1975, has become an important platform to disseminate latest research achievements in the drying field in China with several decades of development. [Extracted from the article]

Source apportionment is crucial to the prevention and control of heavy metals in the soil. The major methods focus on the identification of soil heavy metals from different pollution sources. However, they are unsuited to the source apportionment at a regional scale due to ignoring the spatial heterogeneity of heavy metal content caused by soil formation. Thus, we built a source apportionment model by introducing the weathering and leaching coefficients as the key parameters of soil-forming processes. In this study, we selected Liaohe Plain in China as the study area, which was the starting point of China's industrial development, with dense industrial areas and high levels of heavy-metal emission. Heavy metals concentrations in surface and deep soil of reference and grid points were collected as model data. The results showed that the average contribution rates of soil-forming process to Cd, Hg, As, and Pb were 82.7%, 85.2%, 88.6%, and 91.7%, respectively, and those of anthropogenic activities were 17.3%, 14.8%, 11.4%, and 8.3%, respectively. Spatial distribution of contribution rates showed the superposition of soil environmental background and pollution sources. This study provides a feasible method to quantify heavy metals contents from natural and anthropogenic sources at a regional scale. [Display omitted] • Source apportionment was built for heavy metal of surface soil at regional scale. • Data contained heavy metals in surface and deep soil of reference and grid point. • Nature source content was estimated by weathering and leaching of reference point. • Anthropogenic content was calculated by regression coefficient and grid point value. [ABSTRACT FROM AUTHOR]

Grassland is not only an important part of the terrestrial ecosystem with multiple ecological functions, but also an important base for Chinese herdsmen to produce and live. However, the occurrence and spread of rodent infestation reduces the biodiversity and productivity of grassland ecosystems. It also severely threatens human life, health, and biosecurity through disease transmission. In this study, we explored the ability of the nanocomposite sterilant ND-1 to control grassland rodent populations. Semi-closed experimental and control plots were established in the desert area of Alashan, Inner Mongolia, China. In spring 2018, the nanocomposite sterile ND-1 (Nongda-1) was introduced once, and the control effect of ND-1 on the growth of the wild population of midday gerbils was measured for two years. We show that ND-1 significantly reduced the population of midday gerbils in the experimental area, with a negative population growth rate. In addition, in the second year, the ratio of female midday gerbils to sub-adults in the experimental area was significantly lower than that in the control area, which resulted in a significant difference in the sex ratio of midday gerbils. There were significantly fewer females than males, and the population growth of midday gerbils in the experimental area was significantly inhibited. ND-1 had no significant effect on the home range of midday gerbils, and sterile individuals continued to occupy the home range and consume resources. Therefore, ND-1 reduced the number of female midday gerbils during the breeding period and the sex ratio and population density and altered the age structure of the wild population. Additionally, competition between sterile and normal individuals had a significant control effect on the growth of wild populations. Our studies demonstrate the significance of ND-1 in the sustainable control of grassland rodent pests, with the potential for limiting grassland rodent damage in the future. [ABSTRACT FROM AUTHOR]

Influenza C virus (ICV) was identified in five pediatric acute respiratory cases in Shandong. Co-infection with other respiratory viruses was detected in four of these cases. Two ICV genomes were obtained and clustered in the S1-sublineage of C/Sao Paulo/378/82, indicating that genetically diverse ICV strains have been circulating in mainland China. • Influenza C viruses of the S1-sublineage of C/Sao Paulo were reported in China. • Co-infection with other respiratory viruses was detected. • Genetically diverse ICV strains have been circulating undetected in mainland China. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to evaluate the recent prevalence and the distributions of morphological subtypes of anaemia in the rural population. Design: Anaemia was defined according to the WHO and the Chinese criteria, and the morphological subtypes of anaemia were classified based on the erythrocyte parameters. The age-standardised prevalence was calculated according to the data of the Population Census 2010 in China. Setting: A cross-sectional study in Henan Province. Participants: 33 585 subjects aged 18–79 years old. Results: The standardised prevalence of anaemia across the WHO and the Chinese definitions was 13·63 % and 5·45 %, respectively. Regardless of which criteria was used, the standardised prevalence of anaemia was higher among women than among men and that increased with age in men, while markedly decreased after menopause in women. There were shifts in morphological patterns of anaemia using the WHO and the Chinese criteria that the standardised prevalence of microcytic anaemia was 3·74 % and 2·97 %, normocytic anaemia was 9·20 % and 2·34 %, and macrocytic anaemia was 0·75 % and 0·14 %, respectively. Besides, there were differences in the influencing factors of anaemia according to different criteria or gender. However, age, education level and renal damage were consistently significantly associated with anaemia in all participants. Conclusions: Anaemia may still be a serious health problem in rural China. It is necessary to reformulate prevention and management strategies to reduce the disease burden of anaemia. [ABSTRACT FROM AUTHOR]

Increasing both carbon (C) sequestration and food production is essential for a sustainable future. However, increasing soil C sequestration or graining yield/quality in rice (Oryza sativa L.) systems has been a tradeoff in that pursuing one goal may compromise the other goal. Field experiments were designed to evaluate methane emission and grain yield in two rice systems in southern China, including the traditional double rice with a seedling transplanting system and innovative ratoon rice with a direct seeding system. Grain yield, grain quality, methane (CH 4) emission, and total organic carbon (TOC) loss rate were investigated, and yield-scaled CH 4 gas emission was assessed. It is found that double rice has a higher grain yield than ratoon rice. However, the grain quality (processing, appearance of chalkiness degree and chalky grain percentage, and nutritional quality) of ratoon rice is superior to double rice, especially the ratoon crop. The yield-scaled CH 4 emission of ratoon rice (0.06 kg kg−1) decreased by 49.29% than double rice (0.12 kg kg−1) throughout the growth period. Compared with the TOC loss rate of double rice (2.95 g kg−1), the rate of ratoon rice was lower (1.97 g kg−1). As a result, ratoon rice with direct seeding can not only improve grain quality but also mitigate yield-scaled CH 4 gas emission and TOC loss rate of rice fields. Therefore, we suggest to use ratoon rice with a direct seeding technique to promote agricultural C sequestration. • Highlights (for review). • Ratoon rice with direct seeding decreased the yield-scaled CH 4 gas emission. • Ratoon rice with direct seeding mitigated the soil TOC loss rate. • Ratoon rice with direct seeding increased the grain quality. [ABSTRACT FROM AUTHOR]

Since July 2020, an infectious disease characterized by liver and spleen white focal necrosis has been spreading widely through geese farms in many regions of China. A novel goose orthoreovirus (GRV), designated GRV‐GD2020, was isolated from the liver and spleen of dead geese. Phylogenetic analysis and sequence comparison revealed that all the genes of GRV‐GD2020 clustered with other waterfowl‐origin orthoreovirus. However, the gene constellation of GRV‐GD2020 was not similar to that of any particular strain. Instead, the genomic segments of GRV‐GD2020 showed 27.5–97.3% similarities to that of other waterfowl‐origin orthoreovirus isolates. Waterfowl‐origin orthoreovirus infections characterized by liver and spleen focal necrosis had not emerged in recent years. The re‐emergence of the disease may be related to the recombination of the genome segments of Muscovy duck reovirus (MDRV), GRV, and new‐type duck orthoreovirus. In summary, we determined that the GRV‐GD2020 strain, causing goose liver and spleen focal necrosis, is a new variant of waterfowl‐origin orthoreovirus. [ABSTRACT FROM AUTHOR]

Purpose: A significant shift in meal pattern with frequent eating out was closely associated with multiple chronic outcomes, but with limited evidence on hyperuricemia. We aimed to explore the associations between eating out and serum uric acid (SUA) as well as hyperuricemia. Methods: A total of 29,597 participants were recruited from the Henan Rural Cohort Study. A validated food frequency questionnaire (FFQ) was used to collect dietary data, including the frequency of eating out. Linear regression models were used to examine the association of eating-out frequency with SUA and BMI. Logistic regression and restricted cubic spline were performed to assess the association and dose–response relationship between eating-out frequency and hyperuricemia. The mediation effect of BMI between eating out and the risk of hyperuricemia was evaluated. Results: Eating out was significantly associated with higher SUA levels in the total population and males (P < 0.001). Multivariate-adjusted odds ratios (ORs) with 95% confidence interval (CIs) of hyperuricemia were 1.26 (1.09, 1.46) for the total population and 1.18 (1.00, 1.40) for males (≥ 7 times/week vs 0 time/week). A non-linear positive dose–response relationship between eating-out frequency and hyperuricemia was observed. Furthermore, BMI played a partial mediating role in the relationship between eating out frequency and hyperuricemia, which explained 30.7% in the total population and 44.8% in males. Conclusion: Our findings indicated that eating out was associated with increased SUA levels and elevated hyperuricemia risk in rural China, especially in males. Moreover, the relationship was partly mediated by BMI. Clinical trials: ChiCTR-OOC-15006699 (2015-07-06). [ABSTRACT FROM AUTHOR]

Aims/Introduction: Studies have found that a plant‐based diet was associated with a lower risk of type 2 diabetes, but evidence is scarce on such associations in China. The aim of this study was to investigate whether a plant‐based diet is related to a lower risk of type 2 diabetes among Chinese adults. Materials and Methods: A total of 37,985 participants were enrolled from the Henan Rural Cohort Study. An overall plant‐based diet index (PDI) was created by assigning positive and reverse scores to 12 commonly consumed food groups. Multivariate logistic regression models and restricted cubic spline analysis were performed to estimate the odds ratio (OR) and 95% confidence interval (95% CI). Results: After multivariable adjustment, the risk of type 2 diabetes was inversely associated with the PDI (extreme‐quartile OR = 0.88, 95% CI: 0.79–0.98; P = 0.027), the risk associated with a 1 standard deviation (SD) increase in PDI was 4% lower (95% CI, 0.93–1.00; P trend = 0.043) for type 2 diabetes. Moreover, the odds of type 2 diabetes was decreased with an increment of PDI after fitting restricted cubic splines (Ptrend < 0.01). Conclusions: Among Chinese populations, diets higher in plant foods and lower in animal foods were associated with a reduced risk of type 2 diabetes. [ABSTRACT FROM AUTHOR]

In recent years, the occurrence of fowl adenovirus 2 (FAdV-2) has been on the rise in China, posing a significant threat to the poultry industry. This study aimed to investigate the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The epidemiological analysis revealed the detection of multiple FAdV serotypes, including FAdV-1, FAdV-2, FAdV-3, FAdV-4, FAdV-8a, FAdV-8b, and FAdV-11 serotypes. Among them, FAdV-2 exhibited the highest proportion, accounting for 21.05% (8/38). The complete genomes of these 8 FAdV-2 strains were sequenced. Genetic evolution analysis indicated that these FAdV-2 strains formed a separate branch within the FAdV-D group, sharing 94.60 to 97.90% nucleotide similarity with the reference FAdV-2 and FAdV-11 strains. Notably, the recombination analysis revealed that 5 out of the 8 FAdV-2 strains, exhibited recombination events between FAdV-2 and FAdV-11. The recombination regions involved Hexon, Fiber, ORF19 genes and 3′ end. Furthermore, pathogenicity experiments demonstrated that recombinant FAdV-2 XX strain is capable of inducing mortality rate of 66.70% and causing more severe hepatitis hydropericardium syndrome (HHS) in 6-wk-old specific-pathogen-free chickens. These findings contribute to our understanding of the prevalence, genomic characteristics, and the pathogenicity of FAdV-2, providing foundations for FAdV-2 vaccine development. [ABSTRACT FROM AUTHOR]

The Lianfeng fault zone is located at the junction of the Daliangshan subblock and the South China block and is the southern boundary of the Daliangshan subblock. It is a very active tectonic area, which is of great significance to understanding its seismogenic environment. However, there are relatively little existing data on its activity and the timing of its latest activity. In the Jinyang-Ningnan segment of the Lianfeng fault zone along the Jinsha River, remote sensing image interpretation, field geologic surveys, high-precision drone measurements, and sample dating indicate that the river terraces T1 (the lowest, 15–40 m above the local river level) and T2 (60–90 m above the local river level) developed in the mid-Holocene and late Pleistocene. This indicates that the Jinsha River basin has been strongly downcutting since the Late Pleistocene. The fault profiles are mainly exposed in the T1 and T2 terraces of the Jinsha River. Based on this information in combination with the fault characteristics of the sedimentary profile and stratigraphic dating, it is believed that the Lianfeng fault zone was active at least along the Jinyang-Ningnan segment, with the latest activity occurring no earlier than the early to mid-Holocene. [ABSTRACT FROM AUTHOR]

Hybridization is a widely used and effective method in grouper breeding. In this study, we constructed full-sib families of brown-marbled grouper (Epinephelus fuscoguttatus), Jinhu grouper (E. fuscoguttatus ♀ × E. tukula ♂), and Hulong grouper (E. fuscoguttatus ♀ × E. lanceolatus ♂) and compared the growth characteristics under industrial conditions. The body weight of Jinhu grouper was 1.49 times that of Hulong grouper (P < 0.05) and the body weight of Jinhu grouper was 2.03 times that of E. fuscoguttatus (P < 0.05). Moreover, the survival rate of Jinhu grouper was significantly higher than those of Hulong grouper and E. fuscoguttatus (P < 0.05). The relationships between body length and body weight (W = aLb) in Jinhu grouper, Hulong grouper, and E. fuscoguttatus were similar, and both Jinhu grouper and Hulong grouper may inherit the growth pattern of E. fuscoguttatus. The b values were all <3, indicating allometric relationships at this stage. In a comparison of the low temperature tolerance, E. fuscoguttatus and Jinhu grouper stopped feeding at 19 °C and 16 °C, respectively, and 11 °C and 9 °C were the half-lethal temperatures, respectively. A histopathological analysis showed that the degree of damage in the gill, muscle, and liver tissues increased as the temperature decreased. The activities of total superoxide dismutase (T-SOD), total antioxidant capacity (T-AOC), and glutathione peroxidase (GSH-Px) in the liver decreased initially and then increased as the temperature decreased. The malondialdehyde (MDA) contents in the liver increased initially and decreased thereafter. Lysozyme (LZM) activity in the serum increased initially and then decreased, and immunoglobulin M (IgM) levels did not vary significantly with respect to temperature (P > 0.05). In conclusion, Jinhu grouper was characterized by a rapid growth rate, high survival rate, and low temperature resistance. This hybrid grouper is suitable for industrial culture in China, with broad potential applications • Growth and survival were better in Jinhu grouper than in E. fuscoguttatus and Hulong grouper. • Behavioral, histological, and enzyme responses to low temperature stress were studied. • The half-lethal temperature was lower in Jinhu grouper than in E. fuscoguttatus. [ABSTRACT FROM AUTHOR]

Grouper is an economically important fish in China. However, it exhibits a high frequency of skeletal abnormalities, particularly vertebral deformities. The molecular mechanisms underlying fish vertebral deformities are still poorly understood. In this study, a HiSeq™ 4000 platform (Illumina) was used to analyze the transcriptomic profiles of the brain, pituitary, and vertebrae from normal fish (NF) and fish with lordosis (LF) of Yunlong grouper. A total of 87,888 unigenes were assembled with lengths that varied from 201 to 28,922 bp and a N50 length of 2670 bp. A total of 36,268 unigenes were functionally annotated by BLAST alignments. A total of 2875 significantly differentially expressed genes (DEGs) were identified between the NF group and the LF group, including 706 upregulated unigenes and 2169 downregulated unigenes in LF. GO and KEGG pathway enrichment analyses showed that DNA binding, transmembrane receptor activity, cytokine receptor interaction, neuroactive ligand-receptor interaction, calcium signaling pathway and ECM-receptor interaction HIF-1 signaling pathway, and mineral absorption may be involved in the formation of vertebral deformities. Furthermore, weighted gene co-expression network analyses, including three modules (turquoise, yellow, and blue), significantly positively corrected with vertebral deformities. A network map that included these three modules enabled the identification of a series of hub genes, including claudin-22-like (cldn22), fibronectin type III domain-containing protein 1 isoform X2 (fndc1l2), E3 ubiquitin-protein ligase NRDP1-like (rnf41), and Catenin alpha-2 (ctnna1). We found that the levels of most genes in the blue module were closely related to the expression of parvalbumin, thymic CPV3-like isoform X2 (ocm), platelet glycoprotein Ib alpha chain (gp1ba), and matrix metalloproteinase-9 (mmp9), suggesting that this module is associated with skeletal development. Some uncharacterized genes associated with known bone-related genes, including Unigene0067643, Unigene0056862, and Unigene0059867, were detected by a weighted gene co-expression network analysis. A detailed functional investigation of these networks and genes will further improve our understanding of the molecular mechanisms that underlie the formation of lordosis in fish. • Skletal abnormality is one of the most challenging problems for grouper aquaculture industry. • Transcriptome sequencing was performed on the brain, pituitary and vertebrae to study the lordosis of Yunlong grouper. • WGCNA enabled us to uncover networks and new genes involved in vertebrae development. • Changes in the expression of some genes might disrupt the dynamic balance of vertebrae processes, resulting in lordosis. [ABSTRACT FROM AUTHOR]

We propose an optimal deployment scheme of the Seafloor Observation Network (SON) in the South China Sea (SCS), aiming at early warning of potential tsunami hazards based on the data assimilation approach. The SON is composed of offshore bottom pressure gauges (OBPGs). We design the initial location of OBPGs along the isobaths of 500, 1000, and 2000 m. The energy distribution of the tsunami wavefield based on Empirical Orthogonal Function (EOF) analysis is used as a reference. Then, synthetic tsunamis generated by stochastic slip sources along the Manila Trench are adopted to evaluate the performance of the SON. The OBPGs at a depth of 1000 m can make an accurate early warning based on tsunami data assimilation at a reasonable engineering cost. Finally, based on the quantitative evaluation, the optimal deployment scheme of the SON is suggested. Our results indicate that at least three stations are required to cover the coast along southern China to forecast the tsunami in the SCS successfully. We note that our method could also be applied to other regions to design the SON against potential tsunami hazards. • A tsunami early warning system is designed for the South China Sea. • Data assimilation approach is adopted for tsunami forecasting. • Offshore stations along the 1000-m isobath are most cost-effective. • At least three stations are required for constructing tsunami warning system. [ABSTRACT FROM AUTHOR]