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Background: In this retrospective study, we aimed to evaluate the factors associated with the severity of respiratory syncytial virus (RSV) bronchiolitis in children aged under 2 years who were admitted to the Children's Hospital of Hebei between June 2018 and January 2019. Methods: Sputum samples positive for RSV via multiplex PCR were subtyped using real-time PCR. Data collected included risk factors for disease severity, demographics, microbiology, and outcomes. Results: Of the 82 children with RSV bronchiolitis, 79 were treated and discharged with improvement, while 3 died. All three patients had underlying medical conditions, including complex congenital heart disease and severe combined immunodeficiency. Further, disease severity was associated with preexisting underlying disease, fever duration, and bacterial co-infection, but not with the RSV subtype. Conclusions: Our findings suggest that an appropriate therapeutic regimen should include the detection of bacterial co-infections and the identification of underlying diseases for the effective management of severe RSV bronchiolitis. [ABSTRACT FROM AUTHOR]

In order to screen excellent silage maize varieties suitable for planting in Hebei Province, the basic nutrient composition, mineral element content, energy and related index of six varieties of silage maize in Hebei Province were detected by near-infrared spectroscopy technology, and the quality of six varieties of silage maize was comprehensively evaluated in combination with agronomic traits and biological yield. The results showed that there was no significant difference in agronomic traits among varieties (P>0.05). There was significant difference in biomass among varieties (P<0.05), and Jingke 932 was the highest. The ADF and NDF content of Jinzhu 100 and Dongke 301 were significantly lower than those of the other four varieties (P<0.05). There were significant differences in DM and CP content among varieties (P<0.05). The highest starch content of Jinzhu 100 was 32.3%, which was significantly different from other varieties (P<0.05). The difference of mineral element content among varieties was not significant (P>0.05). There was no significant difference in total digestible nutrients, NEL and NEG of silage maize among different varieties, with Jinzhu 100 and Dongke 301 being the highest, and the milk yield per ton of feed was significantly higher than that of other varieties (P<0.05). The experiment indicates that the near-infrared detection technology can meet the requirements of rapid and accurate determination of the nutritional components of silage maize. According to the analysis of comprehensive nutrient composition and emergy index, Jinzhu 100 and Dongke 301 are of good quality and can be popularized and planted as silage maize in Hebei Province. [ABSTRACT FROM AUTHOR]