Search

Amaç: Kronik böbrek yetmezliği (KBY), böbrek fonksiyonlarının geri dönüşsüz olarak bozulması olarak tanımlanmaktadır. Bu çalışmada KBY nedeni ile hemodiyaliz (HD) tedavisi alan kadın ve erkek hastalarda D Vitamini düzeyinin ayak hareketleri üzerindeki etkisi araştırıldı. Materyal ve Metot: Çalışmaya bilgilendirilmiş gönüllü onam formunu imzalayan, 40-90 yaş arası, haftada 3 kez düzenli olarak HD tedavisi alan,45 erkek ve 45 kadın, toplam 90 HD hastası dahil edildi. Biyokimyasal olarak D Vitamini düzeyi, element düzeyleri ve Parathormon (PTH) seviyeleri hastaların dosyaları incelenerek kaydedildi. Manuel gonyometre kullanılarak ayak bileği plantar fleksiyon, inversiyon ve eversiyon eklem hareket açıklığı ölçüldü. Bulgular: Yaş ortalaması kadınlarda 61,69 ± 15,07 yıl iken erkeklerde 61,49 ± 15,12 yıldır. Serum D vitamini düzeyi açısından cinsiyetler arasındaki fark istatiksel açıdan anlamlı bulunmadı (p>0,05). Beden kitle indeksi (BKİ) değişkenine göre kadınlar ve erkekler arasında istatistiksel olarak anlamlı farklılık bulundu (p

Purpose: Oxidative stress increases in uremic conditions such as kidney failure and during hemodialysis. In this study, it was aimed to examine the relationship between the total antioxidant capacity of the diet and the serum oxidative stress (sOSI) index in hemodialysis patients. Materials and Methods: In this study conducted with 82 individuals (41 patients and 41 controls). Demographic characteristics and anthropometric measurements of the individuals were taken by researchers. In order to determine the nutritional status of the individuals, 3-day food consumption records were taken and the total antioxidant capacity of the diet was calculated. Results: The mean age of the individuals participating in the study was found to be 54.01±2.24 years. Hemodialysis treatment mean for 4.8±3.12 years. While 41.46% of hemodialysis patients were moderately malnourished. Dietary Oxygen Radical Absorption Capacity (dORAC) (μmol) measurement result was found to be 2415.3±1073.45, 5468.4±2393.85 in the hemodialysis and control groups, respectively. In the multiple logistic regression analysis performed, the decrease in body mass index (OR 2.21 95% CI 1.050-2.317) and triceps skinfold thickness values (OR 3.22 95% CI 1.722-4.001) in hemodialysis patients led to an increase in the sOSI value. It has been observed that when dietary protein (OR 1.23 95% CI 1.003-3.189), vitamin C (OR 2.88 95% CI 1.004-3.106) and dTAC (OR 2.04 95% CI 1.967-2.001) increase, the sOSI value decreases in hemodialysis patients. Conclusion: There is a positive relationship between diet total antioxidant capacity and serum antioxidant level, and it was determined that the dietary antioxidant capacity of hemodialysis patients was significantly lower than that of healthy individuals. According to the results of the study, it is recommended to monitor the food consumption status of hemodialysis patients in order to increase the dietary antioxidant capacity.

Aim: Dietary antioxidant intake correlates with blood antioxidant content and protects against oxidative damage and related inflammatory complications. This study was conducted to examine the relationship between total antioxidant capacity of diet and effective factors with laboratory and anthropometric parameters in patients undergoing hemodialysis. Material and Method: The present case-control study consisted of 62 cases and 59 controls individuals who received hemodialysis treatment between the ages of 35-75. Dietary intake, sociodemographic data, medical history, and anthropometric measurements were collected from participants using a validated questionnaire. Results: Examining the association between dietary components and diet's total antioxidant capacity (dTAC) reveals a positive correlation between dietary protein (kg/avg), beta carotene (mcg/day), vitamin C (mg/day), vitamin E (mg/day), and polyunsaturated fatty acids (PUFA) (g/day) (p=0.002). The serum albumin, serum neutrophil to lymphocyte ratio and HDL-cholesterol have been reported to have a positive relationship with dTAC. And body mass ındex (BMI) and other anthropometric parameters were found to have a negative connection with dTAC (p=0.007). Conclusion: Total dietary antioxidant capacity is effective on anthropometric measurements and serum laboratory values. Increasing the antioxidant capacity of the diet in hemodialysis patients is important to prevent complications related to inflammation.