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Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Computer Measurement & Control is the property of Magazine Agency of Computer Measurement & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

AIM: To investigate the role of specific long noncoding RNA SLC25a6 (lncSLC25a6) in homocysteine (Hcy)-induced cuproptosis in cardiomyocytes. METHODS: Rat cardiomyocytes were cultured in vitro and divided into control group and Hcy group. After 48 h of intervention, the expression levels of cuproptosis-related proteins, ferredoxin 1 (FDX1) and heat shock protein 70 (HSP70), were detected by Western blot and immunofluorescence staining. The oxidative stress state of cardiomyocytes was assessed using fluorescence staining, and the intracellular Cu2+ levels were measured using a copper ion assay kit. Furthermore, the impact of Hcy on the expression of cuproptosis-related proteins in cardiomyocytes was analyzed following overexpression of lncSLC25a6. RESULTS: Compared with the control group, 80 μmol/L Hcy significantly accelerated cardiomyocyte damage, with a notable underexpression of lncSLC25a6 (P<0. 05). Western blot results indicated that, compared with the control group, the expression level of FDX1 in the Hcy intervention group was significantly reduced (P<0. 05), while the expression level of HSP70 was significantly elevated (P< 0. 05), and the expression level of copper ions in cardiomyocytes of the Hcy group was increased (P<0. 05). Immunofluorescence staining showed a significant reduction in FDX1 fluorescence intensity and a significant increase in HSP70 fluorescence intensity in the Hcy group. Further overexpression of lncSLC25a6 significantly mitigated Hcy-induced cuproptosis in cardiomyocytes, resulting in elevated expression of FDX1 and reduced expression of HSP70 (P<0. 05). Pearson correlation analysis demonstrated that the expression level of lncSLC25a6 was negatively correlated with FDX1 protein expression (r= − 0. 676, P=0. 046) and positively correlated with HSP70 expression (r=0. 680, P=0. 044). CONCLUSION: lncSLC25a6 significantly mitigates Hcy-induced cuproptosis in cardiomyocytes, positioning it as a potential therapeutic target for managing Hcy-induced cardiac injury. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Nanchang University (Engineering & Technology) is the property of Nanchang University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Mechanical Engineering is the property of Editorial Board of China Mechanical Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: The Akagi line and range-of-motion (ROM) technique are widely used for locating the tibial prosthesis during total knee arthroplasty; however, there is still a lack of relevant research on the size and source of the difference between the two positioning methods. OBJECTIVE: To compare the differences of Akagi line and ROM technique in varus knee during total knee arthroplasty, and to discuss the causes of this difference. METHODS: Totally 70 patients with varus knee who underwent total knee arthroplasty in the Department of Orthopedics, Guangdong Hospital of Traditional Chinese Medicine from July to December 2021 were enrolled in this study. All operations were performed with the posterior cruciate-stabilizing total knee prostheses. The femorotibial angle, lateral distal femoral angle, medial proximal tibial angle, and joint line convergence angle were measured before operation. Its difference from normal was calculated. The angle α between Akagi line and ROM technique was measured during operation. The angles that measured preoperatively and α were statistically tested by using correlation analysis and multiple linear regression analysis. RESULTS AND CONCLUSION: (1) Before operation, Δ mechanical femoral-tibial angle was (10.90±4.82)°; Δ anatomic tibiofemoral angle was (10.81±4.34)°; Δ mechanical lateral distal femoral angle was (-3.26±2.68)°; Δ anatomic lateral distal femoral angle was (-3.00±2.30)°; Δ mechanical medial proximal tibial angle was (2.39±3.05)°; Δ anatomic medial proximal tibial angle was (2.98±3.31)°; Δ joint line convergence angle was (4.71±2.52)°; the α that measured during operation was (2.39±2.50)°. (2) Totally 53 cases selected Akagi line and 13 cases selected ROM technique for locating the tibial prosthesis finally. (3) Statistical analysis results showed that Δ mechanical medial proximal tibial angle and Δ anatomic medial proximal tibial angle had a significant positive effect on α (P < 0.01), and the regression equations were α=0.658±0.432×Δ mechanical medial proximal tibial angle and α=0.013±0.346×Δ anatomic medial proximal tibial angle respectively. (4) The results suggest that there is a difference between Akagi line and ROM technique when locating the tibial prosthesis for patients with varus knee undergoing total knee arthroplasty, and this difference (α) is positively correlated with the degree of proximal tibial varus deformity [ABSTRACT FROM AUTHOR]

【Objective/Meaning】The free trade agreement (FTA) was beneficial to the trade between the two countries and could promote the economic development. 【Methods/Procedures】The four indexes of TII, T, RCA and TCI were calculated by using the Excel function with the import and export trade volume of dairy products between China and New Zealand in the UN Comtrade database from 2000 to 2020. The index changes in the two periods before and after the signing of the FTA were compared and analyzed, and the gravity model was established by using the Stata software based on the trade data of the top five dairy import source countries with China from 2000 to 2020 in the UN Comtrade database, in order to study the impact of FTA on the dairy trade between China and New Zealand. 【Results/Conclusions】The results showed that the dairy products in New Zealand had great export advantages, and the signing of FTA has deepened the complementarity between the import trade of dairy products in China and the export trade of dairy products in New Zealand. The gravity model showed that FTA was positively correlated with the trade volume of dairy products between China and New Zealand, the difference in GDP between the two countries had a positive impact on the import volume of dairy products in China, and the transportation cost between the two countries had a negative impact on the import volume of dairy products in China. The trade volume of dairy products between China and New Zealand generally showed an increasing tendency. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Materials Engineering / Cailiao Gongcheng is the property of Journal of Materials Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Foreign Literature Studies is the property of Foreign Literature Studies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)