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Adventitial cystic disease (ACD) is a rare condition that typically presents in young healthy men with symptoms of claudication. ACD is characterized by formation of a mucinous cyst within the adventitia of a blood vessel, usually in the popliteal artery, causing compression of the vessel’s lumen and leading to reduced flow and symptoms of claudication. We have presented a rare case of ACD of the common femoral artery in a young female patient that was treated successfully with resection and femoral vein graft interposition reconstruction.

We report the case of a 61-year-old man who had presented with acute unilateral limb swelling. Computed tomography venography and duplex ultrasound demonstrated compression of the right common femoral vein by a common femoral vein adventitial cyst. Before intervention, the patient had developed an acute deep vein thrombosis of the right common femoral vein and great saphenous vein. Preoperative magnetic resonance imaging demonstrated concern for synovial connection. After 6 months of anticoagulation therapy, the patient underwent adventitial cyst excision with ligation of the hip joint articular connection. At 4 months postoperatively, the patient was symptom free without cyst recurrence. The findings from the present case support the synovial theory for adventitial cystic disease.

Adventitial Cystic Disease (ACD) is a rare cause of peripheral arterial disease that accounts for less than 1% of all causes of claudication. It typically presents in younger individuals and surgical reconstruction is the mainstay of treatment. We report a case of a 60-year-old, active female with progressively worsening claudication, who presented with ultrasound and computed tomography angiography revealing ACD involving the common femoral artery. The patient underwent a complete resection of the affected artery, which was replaced with an interposition Dacron bypass graft. We also present a comprehensive review of literature on surgical management of ACD of the femoral artery.

Adventitial Cystic Disease (ACD) is a vastly rare non-atherosclerotic vascular pathology that is principally manifested as intermittent claudication because of peripheral vascular ischemia. Precise etiological factors are not yet concretely identified, and it represents 0.1 % of all lower limb claudication causes. Middle-aged males are the most affected gender age group. Misdiagnosis of Popliteal Artery ACD could delay proper management and hence risk the loss of the affected limb due to critical limb ischemia. We hereby explore the rare case of a 51-year-old female patient, who complained of vague left lower extremity pain accompanied by paresthesia for 1 month prior to admission without signs of local inflammation. The preoperative radiological assessment suggested the presence of thrombosis within the left Popliteal Artery which caused an occlusion in it and hence the proper blood flow was compromised. Surgical intervention and the complete removal of the lesion along with establishing a patent synthetic anastomotic graft to maintain the preexisting vascular bundle was the key to treating our patient. Microscopic analysis of the excised specimen revealed an Adventitial Cystic Disease of the Popliteal Artery. Adventitial Cystic Disease represents an extremely rare vascular pathology with a vast margin of non-specific symptoms that could lead to misdiagnoses. It is fundamental to establish suitable preoperative screening protocols for it and sustain adequate levels of clinical awareness so that we can timely diagnose and in turn, achieve proper therapeutic interventions to plummet the potential disastrous complications that could ensue. • Adventitial Cystic Disease is a rare non-atherosclerotic vascular disease with ambiguous etiology. • Adventitial Cystic Disease comprises merely 0.1 % of the cases of lower limb intermittent claudication. • The prevalence of ACD among patients with vascular claudication is estimated to be 1 in 1200 cases. • ACD tends to occur more prominently in young to middle-aged males where the male-to-female ratio is 15:1. • Duplex ultrasound is key to diagnosing it and surgical excision limits the possibility of recurrence. [ABSTRACT FROM AUTHOR]