Search

The current study aimed to examine the relationships between item-based tests and a narrative retelling by analyzing concurrent associations, regression coefficients, language progress, and sex differences. Thirty-one kindergarteners with typical language development were assessed at the beginning (Mage = 64.77 months) and the end of the school year. The statistically significant associations and predictive relations between the item-based tests and narrative retelling were scarce and occurred mainly at the same language level (words and sentences). Accordingly, language progression was mirrored differently by the two assessment conditions. Sex was not related to language skills. Overall, the results indicate these two kinds of tools assess different language constructs and should be used complementarily. Additionally, two relatively innovative trends emerged: errors produced in the narrative seem to be a good discriminative metric for this age range, and testing language by units (words and sentences) might be appropriate to assess language development.

Novel multicomponent crystal forms were obtained from reactions of trans-disubstituted cyclam derivatives with flufenamic and salicylic acids. The reactions of H2(4-CF3PhCH2)2cyclam with those acids led to the formation of salts of the formulae [H2{H2(4-CF3PhCH2)2cyclam}](3-CF3PhNHC6H4COO)2 and [H2{H2(4-CF3PhCH2)2cyclam}](HOC6H4COO)2, respectively. The reaction of H2(PhCH2)2cyclam with flufenamic acid led to the formation of the salt [H2{H2(PhCH2)2cyclam}](3-CF3PhNHC6H4COO)2, whereas its reaction with salicylic acid afforded the ionic cocrystal [H2(PhCH2)2cyclam](HOC6H4COOH)2·[H2{H2(PhCH2)2cyclam}](HOC6H4COO)2. The compounds obtained were fully characterized and tested against several yeasts as well as Gram-positive and Gram-negative bacterial strains. The results have shown that the new multicomponent forms display relevant antimicrobial activity when compared to their parent cyclam derivatives, highlighting the importance of exploring synergistic effects to unveil new and efficient antimicrobial agents. [ABSTRACT FROM AUTHOR]