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Your search keyword '"Amatullah, Hajera"' showing total 9 results
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9 results on '"Amatullah, Hajera"'

1. DJ-1 binds to Rubicon to Impair LC-3 Associated Phagocytosis

Author

Gupta, Sahil, Amatullah, Hajera, Tsoporis, James N., Wei, Kuiru, Monteiro, Ana Paula Teixeira, Ektesabi, Amin M., Varkouhi, Amir K., Vaswani, Chirag M., Formosa, Amanda, Fabro, Alexandre T., Batchu, Sri Nagarjun, Fjell, Chris, Russell, James A., Walley, Keith R., Advani, Andrew, Parker, Thomas G., Marshall, John C., Rocco, Patricia R. M., Fairn, Gregory D., Mak, Tak Wah, and dos Santos, Claudia C.

Published
2022
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4. NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils

Author

Zhu, Yanfang Peipei, primary, Speir, Mary, additional, Tan, ZheHao, additional, Lee, Jamie Casey, additional, Nowell, Cameron J., additional, Chen, Alyce A., additional, Amatullah, Hajera, additional, Salinger, Ari J., additional, Huang, Carolyn J., additional, Wu, Gio, additional, Peng, Weiqi, additional, Askari, Kasra, additional, Griffis, Eric, additional, Ghassemian, Majid, additional, Santini, Jennifer, additional, Gerlic, Motti, additional, Kiosses, William B., additional, Catz, Sergio D., additional, Hoffman, Hal M., additional, Greco, Kimberly F., additional, Weller, Edie, additional, Thompson, Paul R., additional, Wong, Lai Ping, additional, Sadreyev, Ruslan, additional, Jeffrey, Kate L., additional, and Croker, Ben A., additional

Published
2023
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5. DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression

Author

Tsoporis, James N., primary, Amatullah, Hajera, additional, Gupta, Sahil, additional, Izhar, Shehla, additional, Ektesabi, Amin M., additional, Vaswani, Chirag M., additional, Desjardins, Jean-Francois, additional, Kabir, Golam, additional, Teixera Monteiro, Ana Paula, additional, Varkouhi, Amir K., additional, Kavantzas, Nikolaos, additional, Salpeas, Vasileios, additional, Rizos, Ioannis, additional, Marshall, John C., additional, Parker, Thomas G., additional, Leong-Poi, Howard, additional, and dos Santos, Claudia C., additional

Published
2023
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7. Sleep exerts lasting effects on hematopoietic stem cell function and diversity

Author

McAlpine, Cameron S., primary, Kiss, Máté G., additional, Zuraikat, Faris M., additional, Cheek, David, additional, Schiroli, Giulia, additional, Amatullah, Hajera, additional, Huynh, Pacific, additional, Bhatti, Mehreen Z., additional, Wong, Lai-Ping, additional, Yates, Abi G., additional, Poller, Wolfram C., additional, Mindur, John E., additional, Chan, Christopher T., additional, Janssen, Henrike, additional, Downey, Jeffrey, additional, Singh, Sumnima, additional, Sadreyev, Ruslan I., additional, Nahrendorf, Matthias, additional, Jeffrey, Kate L., additional, Scadden, David T., additional, Naxerova, Kamila, additional, St-Onge, Marie-Pierre, additional, and Swirski, Filip K., additional

Published
2022
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8. Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation

Author

Adiliaghdam, Fatemeh, primary, Amatullah, Hajera, additional, Digumarthi, Sreehaas, additional, Saunders, Tahnee L., additional, Rahman, Raza-Ur, additional, Wong, Lai Ping, additional, Sadreyev, Ruslan, additional, Droit, Lindsay, additional, Paquette, Jean, additional, Goyette, Philippe, additional, Rioux, John D., additional, Hodin, Richard, additional, Mihindukulasuriya, Kathie A., additional, Handley, Scott A., additional, and Jeffrey, Kate L., additional

Published
2022
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9. NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils.

Author

Yanfang Peipei Zhu, Speir, Mary, ZheHao Tan, Lee, Jamie Casey, Nowell, Cameron J., Chen, Alyce A., Amatullah, Hajera, Salinger, Ari J., Huang, Carolyn J., Gio Wu, Weiqi Peng, Askari, Kasra, Griffis, Eric, Ghassemian, Majid, Santini, Jennifer, Gerlic, Motti, Kiosses, William B., Catz, Sergio D., Hoffman, Hal M., and Greco, Kimberly F.

Abstract

Neutrophil extracellular traps (NETs) not only counteract bacterial and fungal pathogens but can also promote thrombosis, autoimmunity, and sterile inflammation. The presence of citrullinated histones, generated by the peptidylarginine deiminase 4 (PAD4), is synonymous with NETosis and is considered independent of apoptosis. Mitochondrial- and death receptor-mediated apoptosis promote gasdermin E (GSDME)-dependent calcium mobilization and membrane permeabilization leading to histone H3 citrullination (H3Cit), nuclear DNA extrusion, and cytoplast formation. H3Cit is concentrated at the promoter in bone marrow neutrophils and redistributes in a coordinated process from promoter to intergenic and intronic regions during apoptosis. Loss of GSDME prevents nuclear and plasma membrane disruption of apoptotic neutrophils but prolongs early apoptosisinduced cellular changes to the chromatin and cytoplasmic granules. Apoptotic signaling engages PAD4 in neutrophils, establishing a cellular state that is primed for NETosis, but that occurs only upon membrane disruption by GSDME, thereby redefining the end of life for neutrophils. [ABSTRACT FROM AUTHOR]

Published
2023
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