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Your search keyword '"Asamaphan P."' showing total 7 results
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7 results on '"Asamaphan P."'

1. Adeno-associated virus 2 infection in children with non-A–E hepatitis

Author

Ho, Antonia, Orton, Richard, Tayler, Rachel, Asamaphan, Patawee, Herder, Vanessa, Davis, Chris, Tong, Lily, Smollett, Katherine, Manali, Maria, Allan, Jay, Rawlik, Konrad, McDonald, Sarah E., Vink, Elen, Pollock, Louisa, Gannon, Louise, Evans, Clair, McMenamin, Jim, Roy, Kirsty, Marsh, Kimberly, Divala, Titus, Holden, Matthew T. G., Lockhart, Michael, Yirrell, David, Currie, Sandra, O’Leary, Maureen, Henderson, David, Shepherd, Samantha J., Jackson, Celia, Gunson, Rory, MacLean, Alasdair, McInnes, Neil, Bradley-Stewart, Amanda, Battle, Richard, Hollenbach, Jill A., Henderson, Paul, Odam, Miranda, Chikowore, Primrose, Oosthuyzen, Wilna, Chand, Meera, Hamilton, Melissa Shea, Estrada-Rivadeneyra, Diego, Levin, Michael, Avramidis, Nikos, Pairo-Castineira, Erola, Vitart, Veronique, Wilkie, Craig, Palmarini, Massimo, Ray, Surajit, Robertson, David L., da Silva Filipe, Ana, Willett, Brian J., Breuer, Judith, Semple, Malcolm G., Turner, David, Baillie, J. Kenneth, and Thomson, Emma C.

Published
2023
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2. SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Author

Willett, Brian J., Grove, Joe, MacLean, Oscar A., Wilkie, Craig, De Lorenzo, Giuditta, Furnon, Wilhelm, Cantoni, Diego, Scott, Sam, Logan, Nicola, Ashraf, Shirin, Manali, Maria, Szemiel, Agnieszka, Cowton, Vanessa, Vink, Elen, Harvey, William T., Davis, Chris, Asamaphan, Patawee, Smollett, Katherine, Tong, Lily, Orton, Richard, Hughes, Joseph, Holland, Poppy, Silva, Vanessa, Pascall, David J., Puxty, Kathryn, da Silva Filipe, Ana, Yebra, Gonzalo, Shaaban, Sharif, Holden, Matthew T. G., Pinto, Rute Maria, Gunson, Rory, Templeton, Kate, Murcia, Pablo R., Patel, Arvind H., Klenerman, Paul, Dunachie, Susanna, Haughney, John, Robertson, David L., Palmarini, Massimo, Ray, Surajit, and Thomson, Emma C.

Published
2022
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3. Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Author

Willett, Brian J., Grove, Joe, MacLean, Oscar A., Wilkie, Craig, De Lorenzo, Giuditta, Furnon, Wilhelm, Cantoni, Diego, Scott, Sam, Logan, Nicola, Ashraf, Shirin, Manali, Maria, Szemiel, Agnieszka, Cowton, Vanessa, Vink, Elen, Harvey, William T., Davis, Chris, Asamaphan, Patawee, Smollett, Katherine, Tong, Lily, Orton, Richard, Hughes, Joseph, Holland, Poppy, Silva, Vanessa, Pascall, David J., Puxty, Kathryn, da Silva Filipe, Ana, Yebra, Gonzalo, Shaaban, Sharif, Holden, Matthew T. G., Pinto, Rute Maria, Gunson, Rory, Templeton, Kate, Murcia, Pablo R., Patel, Arvind H., Klenerman, Paul, Dunachie, Susanna, Haughney, John, Robertson, David L., Palmarini, Massimo, Ray, Surajit, and Thomson, Emma C.

Published
2022
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4. Adeno-associated virus 2 infection in children with non-A–E hepatitis

Author

Ho, A. Orton, R. Tayler, R. Asamaphan, P. Herder, V. Davis, C. Tong, L. Smollett, K. Manali, M. Allan, J. Rawlik, K. McDonald, S.E. Vink, E. Pollock, L. Gannon, L. Evans, C. McMenamin, J. Roy, K. Marsh, K. Divala, T. Holden, M.T.G. Lockhart, M. Yirrell, D. Currie, S. O’Leary, M. Henderson, D. Shepherd, S.J. Jackson, C. Gunson, R. MacLean, A. McInnes, N. Bradley-Stewart, A. Battle, R. Hollenbach, J.A. Henderson, P. Odam, M. Chikowore, P. Oosthuyzen, W. Chand, M. Hamilton, M.S. Estrada-Rivadeneyra, D. Levin, M. Avramidis, N. Pairo-Castineira, E. Vitart, V. Wilkie, C. Cunnington, A. Herberg, J. Kaforou, M. Wright, V. Bellos, E. Broderick, C. Channon-Wells, S. Cooray, S. De, T. D’Souza, G. Elorrieta, L.E. Galassini, R. Habgood-Coote, D. Hamilton, S. Jackson, H. Kavanagh, J. Marjaneh, M.M. Menikou, S. Nichols, S. Nijman, R. Patel, H. Pennisi, I. Powell, O. Reid, R. Shah, P. Vito, O. Whittaker, E. Wilson, C. Womersley, R. Abdulla, A. Darnell, S. Mustafa, S. Georgiou, P. Manzano, J.-R. Moser, N. Pennisi, I. Carter, M. Tibby, S. Cohen, J. Davis, F. Kenny, J. Wellman, P. White, M. Fish, M. Jennings, A. Shankar-Hari, M. Fidler, K. Agranoff, D. Richmond, V. Seal, M. Faust, S. Owen, D. Ensom, R. McKay, S. Mondo, D. Shaji, M. Schranz, R. Rughnani, P. Anpananthar, A. Liebeschuetz, S. Riddell, A. Khalid, N. Malcolm, I.L. Simagan, T. Peters, M. Bamford, A. O’Neill, L. Pathan, N. Daubney, E. White, D. Heightman, M. Eisen, S. Segal, T. Wellings, L. Drysdale, S.B. Branch, N. Hamzah, L. Jarman, H. Nyirenda, M. Capozzi, L. Gardiner, E. Moots, R. Nasher, M. Hanson, A. Linforth, M. O’Riordan, S. Ellis, D. Deep, A. Caro, I. Shackley, F. Bellini, A. Gormley, S. Neshat, S. Scholefield, B.J. Robbins, C. Winmill, H. Paulus, S.C. Pollard, A.J. Anthony, M. Hopton, S. Miller, D. Oliver, Z. Beer, S. Ward, B. Shrestha, S. Pollard, A.J. Gurung, M. Amatya, P. Pokhrel, B. Bijukchhe, S.M. Lubinda, T. Kelly, S. O’Reilly, P. Martinón-Torres, F. Salas, A. González, F.Á. Bello, X. Ben García, M. Carnota, S and Ho, A. Orton, R. Tayler, R. Asamaphan, P. Herder, V. Davis, C. Tong, L. Smollett, K. Manali, M. Allan, J. Rawlik, K. McDonald, S.E. Vink, E. Pollock, L. Gannon, L. Evans, C. McMenamin, J. Roy, K. Marsh, K. Divala, T. Holden, M.T.G. Lockhart, M. Yirrell, D. Currie, S. O’Leary, M. Henderson, D. Shepherd, S.J. Jackson, C. Gunson, R. MacLean, A. McInnes, N. Bradley-Stewart, A. Battle, R. Hollenbach, J.A. Henderson, P. Odam, M. Chikowore, P. Oosthuyzen, W. Chand, M. Hamilton, M.S. Estrada-Rivadeneyra, D. Levin, M. Avramidis, N. Pairo-Castineira, E. Vitart, V. Wilkie, C. Cunnington, A. Herberg, J. Kaforou, M. Wright, V. Bellos, E. Broderick, C. Channon-Wells, S. Cooray, S. De, T. D’Souza, G. Elorrieta, L.E. Galassini, R. Habgood-Coote, D. Hamilton, S. Jackson, H. Kavanagh, J. Marjaneh, M.M. Menikou, S. Nichols, S. Nijman, R. Patel, H. Pennisi, I. Powell, O. Reid, R. Shah, P. Vito, O. Whittaker, E. Wilson, C. Womersley, R. Abdulla, A. Darnell, S. Mustafa, S. Georgiou, P. Manzano, J.-R. Moser, N. Pennisi, I. Carter, M. Tibby, S. Cohen, J. Davis, F. Kenny, J. Wellman, P. White, M. Fish, M. Jennings, A. Shankar-Hari, M. Fidler, K. Agranoff, D. Richmond, V. Seal, M. Faust, S. Owen, D. Ensom, R. McKay, S. Mondo, D. Shaji, M. Schranz, R. Rughnani, P. Anpananthar, A. Liebeschuetz, S. Riddell, A. Khalid, N. Malcolm, I.L. Simagan, T. Peters, M. Bamford, A. O’Neill, L. Pathan, N. Daubney, E. White, D. Heightman, M. Eisen, S. Segal, T. Wellings, L. Drysdale, S.B. Branch, N. Hamzah, L. Jarman, H. Nyirenda, M. Capozzi, L. Gardiner, E. Moots, R. Nasher, M. Hanson, A. Linforth, M. O’Riordan, S. Ellis, D. Deep, A. Caro, I. Shackley, F. Bellini, A. Gormley, S. Neshat, S. Scholefield, B.J. Robbins, C. Winmill, H. Paulus, S.C. Pollard, A.J. Anthony, M. Hopton, S. Miller, D. Oliver, Z. Beer, S. Ward, B. Shrestha, S. Pollard, A.J. Gurung, M. Amatya, P. Pokhrel, B. Bijukchhe, S.M. Lubinda, T. Kelly, S. O’Reilly, P. Martinón-Torres, F. Salas, A. González, F.Á. Bello, X. Ben García, M. Carnota, S

Abstract

An outbreak of acute hepatitis of unknown aetiology in children was reported in Scotland1 in April 2022 and has now been identified in 35 countries2. Several recent studies have suggested an association with human adenovirus with this outbreak, a virus not commonly associated with hepatitis. Here we report a detailed case–control investigation and find an association between adeno-associated virus 2 (AAV2) infection and host genetics in disease susceptibility. Using next-generation sequencing, PCR with reverse transcription, serology and in situ hybridization, we detected recent infection with AAV2 in plasma and liver samples in 26 out of 32 (81%) cases of hepatitis compared with 5 out of 74 (7%) of samples from unaffected individuals. Furthermore, AAV2 was detected within ballooned hepatocytes alongside a prominent T cell infiltrate in liver biopsy samples. In keeping with a CD4+ T-cell-mediated immune pathology, the human leukocyte antigen (HLA) class II HLA-DRB1*04:01 allele was identified in 25 out of 27 cases (93%) compared with a background frequency of 10 out of 64 (16%; P = 5.49 × 10−12). In summary, we report an outbreak of acute paediatric hepatitis associated with AAV2 infection (most likely acquired as a co-infection with human adenovirus that is usually required as a ‘helper virus’ to support AAV2 replication) and disease susceptibility related to HLA class II status. © 2023, The Author(s), under exclusive licence to Springer Nature Limited.

Published
2023

5. Adeno-associated virus 2 infection in children with non-A–E hepatitis

Author

Ho A, Orton R, Tayler R, Asamaphan P, herder V, Davis C, Tong L, Smollett K, Manali M, Allen J, Rawlik K, McDonald SE, Vink E, Pollock L, Gannon L, Evans C, McMenamin J, Roy K, Marsh K, Divala T, Holden MTG, Lockhart M, Yirrell D, Currie S, O'Leary M, Henderson D, Shepherd SJ, Jackson C, Gunson R, MacLean A, McInnes N, Bradley-Stewart A, Battle R, Hollenbach J, Henderson P, Odam M, Chikowore P, Oosthuyzen W, Chand M, Hamilton MS, Estrada-Rivadeneyra D, Levin M, Avramidis N, Pairo-Castineira E, Vitart V, Wilkie C, Ray S, Emonts,M, Bell,A, Bell,K, Fabian,D, Isaacs,J, Lim,E, Shenton,G, Treloar,O, Van Der Veldon,F, DIAMONDS Consortium, ISARIC4C Investigators

Published
2023
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6. SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway (vol 7, pg 1161, 2022)

Author

Willett, BJ, Grove, J, MacLean, OA, Wilkie, C, De Lorenzo, G, Furnon, W, Cantoni, D, Scott, S, Logan, N, Ashraf, S, Manali, M, Szemiel, A, Cowton, V, Vink, E, Harvey, WT, Davis, C, Asamaphan, P, Smollett, K, Tong, L, Orton, R, Hughes, J, Holland, P, Silva, V, Pascall, DJ, Puxty, K, Da Silva Filipe, A, Yebra, G, Shaaban, S, Holden, MTG, Pinto, RM, Gunson, R, Templeton, K, Murcia, PR, Patel, AH, Klenerman, P, Dunachie, S, Haughney, J, Robertson, DL, Palmarini, M, Ray, S, and Thomson, EC

Published
2022

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