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Your search keyword '"Bacigalupo, Andrea"' showing total 291 results
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291 results on '"Bacigalupo, Andrea"'

1. Harmonizing definitions for hematopoietic recovery, graft rejection, graft failure, poor graft function, and donor chimerism in allogeneic hematopoietic cell transplantation: a report on behalf of the EBMT, ASTCT, CIBMTR, and APBMT

Author

Sureda, Anna, Carpenter, Paul A., Bacigalupo, Andrea, Bhatt, Vijaya Raj, de la Fuente, Josu, Ho, Aloysius, Kean, Leslie, Lee, Jong Wook, Sánchez-Ortega, Isabel, Savani, Bipin N., Schetelig, Johannes, Stadtmauer, Edward A., Takahashi, Yoshiyuki, Atsuta, Yoshiko, Koreth, John, Kröger, Nicolaus, Ljungman, Per, Okamoto, Shinichiro, Popat, Uday, Soiffer, Robert, Stefanski, Heather E., and Kharfan-Dabaja, Mohamed A.

Published
2024
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2. Multifield asymptotic homogenization scheme for periodic Cauchy materials in non-standard thermoelasticity

Author

Del Toro, Rosaria, De Bellis, Maria Laura, Vasta, Marcello, and Bacigalupo, Andrea

Subjects
Mathematical Physics
Abstract

This article presents a multifield asymptotic homogenization scheme for the analysis of Bloch wave propagation in non-standard thermoelastic periodic materials, leveraging on the Green-Linsdsay theory that accounts for two relaxation times. The procedure involves several steps. Firstly, an asymptotic expansion of the micro-fields is performed, considering the characteristic size of the microstructure. By utilizing the derived microscale field equations and asymptotic expansions, a series of recursive differential problems are solved within the repetitive unit cell Q. These problems are then expressed in terms of perturbation functions, which incorporate the material's geometric, physical, and mechanical properties, as well as the microstructural heterogeneities. The down-scaling relation, which connects the microscopic and macroscopic fields along with their gradients through the perturbation functions, is then established in a consistent manner. Subsequently, the average field equations of infinite order are obtained by substituting the down-scaling relation into the microscale field equations. To solve these average field equations, an asymptotic expansion of the macroscopic fields is performed based on the microstructural size, resulting in a sequence of macroscopic recursive problems. To illustrate the methodology, a bi-phase layered material is introduced as an example. The dispersion curves obtained from the non-local homogenization scheme are compared with those obtained from the Floquet-Bloch theory. This analysis helps validate the effectiveness and accuracy of the proposed approach in predicting the wave propagation behavior in the considered non-standard thermoelastic periodic materials.

Published
2023

5. Haploidentical HCT

Author

Bacigalupo, Andrea, Lankester, Arjan, Ciceri, Fabio, Bertaina, Alice, Sureda, Anna, editor, Corbacioglu, Selim, editor, Greco, Raffaella, editor, Kröger, Nicolaus, editor, and Carreras, Enric, editor

Published
2024
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8. The generalized Floquet-Bloch spectrum for periodic thermodiffusive layered materials

Author

Fantoni, Francesca, Morini, Lorenzo, Bacigalupo, Andrea, and Paggi, Marco

Subjects
Computer Science - Computational Engineering, Finance, and Science
Abstract

The dynamic behaviour of periodic thermodiffusive multi-layered media excited by harmonic oscillations is studied. In the framework of linear thermodiffusive elasticity, periodic laminates, whose elementary cell is composed by an arbitrary number of layers, are considered. The generalized Floquet-Bloch conditions are imposed, and the universal dispersion relation of the composite is obtained by means of an approach based on the formal solution for a single layer together with the transfer matrix method. The eigenvalue problem associated with the dispersion equation is solved by means of an analytical procedure based on the symplecticity properties of the transfer matrix to which corresponds a palindromic characteristic polynomial, and the frequency band structure associated to wave propagating inside the medium are finally derived. The proposed approach is tested through illustrative examples where thermodiffusive multilayered structures of interest for renewable energy devices fabrication are analyzed. The effects of thermodiffusion coupling on both the propagation and attenuation of Bloch waves in these systems are investigated in detail.

Published
2021

13. Indication and management of allogeneic haematopoietic stem-cell transplantation in myelofibrosis: updated recommendations by the EBMT/ELN International Working Group

Author

Kröger, Nicolaus, Bacigalupo, Andrea, Barbui, Tiziano, Ditschkowski, Markus, Gagelmann, Nico, Griesshammer, Martin, Gupta, Vikas, Hamad, Nada, Harrison, Claire, Hernandez-Boluda, Juan Carlos, Koschmieder, Steffen, Jain, Tania, Mascarenhas, John, Mesa, Ruben, Popat, Uday R, Passamonti, Francesco, Polverelli, Nicola, Rambaldi, Alessandro, Robin, Marie, Salit, Rachel B, Schroeder, Thomas, Scott, Bart L, Tamari, Roni, Tefferi, Ayalew, Vannucchi, Alessandro M, McLornan, Donal P, and Barosi, Giovanni

Published
2024
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19. Impact of second-degree related donor on the outcomes of T cell-replete haploidentical transplantation with post-transplant cyclophosphamide

Author

Mariotti, Jacopo, Raiola, Anna Maria, Evangelista, Andrea, Harbi, Samia, Patriarca, Francesca, Carella, Michele Angelo, Martino, Massimo, Risitano, Antonio, Busca, Alessandro, Giaccone, Luisa, Brunello, Lucia, Merla, Emanuela, Savino, Lucia, Loteta, Barbara, Console, Giuseppe, Fanin, Renato, Sperotto, Alessandra, Marano, Luana, Marotta, Serena, Frieri, Camilla, Sica, Simona, Chiusolo, Patrizia, Chabannon, Christian, Furst, Sabine, Santoro, Armando, Bacigalupo, Andrea, Bruno, Benedetto, Blaise, Didier, Mavilio, Domenico, Bramanti, Stefania, Devillier, Raynier, Angelucci, Emanuele, and Castagna, Luca

Published
2022
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25. On Principal Component Analysis of the Convex Combination of Two Data Matrices and Its Application to Acoustic Metamaterial Filters

Author

Gnecco, Giorgio, Bacigalupo, Andrea, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Nicosia, Giuseppe, editor, Ojha, Varun, editor, La Malfa, Emanuele, editor, La Malfa, Gabriele, editor, Jansen, Giorgio, editor, Pardalos, Panos M., editor, Giuffrida, Giovanni, editor, and Umeton, Renato, editor

Published
2022
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37. A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia

Author

Mascarenhas, John, Kosiorek, Heidi E., Prchal, Josef T., Rambaldi, Alessandro, Berenzon, Dmitriy, Yacoub, Abdulraheem, Harrison, Claire N., McMullin, Mary Frances, Vannucchi, Alessandro M., Ewing, Joanne, O'Connell, Casey L., Kiladjian, Jean-Jacques, Mead, Adam J., Winton, Elliott F., Leibowitz, David S., De Stefano, Valerio, Arcasoy, Murat O., Kessler, Craig M., Catchatourian, Rosalind, Rondelli, Damiano, Silver, Richard T., Bacigalupo, Andrea, Nagler, Arnon, Kremyanskaya, Marina, Levine, Max F., Arango Ossa, Juan E., McGovern, Erin, Sandy, Lonette, Salama, Mohamad E., Najfeld, Vesna, Tripodi, Joseph, Farnoud, Noushin, Penson, Alexander V., Weinberg, Rona Singer, Price, Leah, Goldberg, Judith D., Barbui, Tiziano, Marchioli, Roberto, Tognoni, Gianni, Rampal, Raajit K., Mesa, Ruben A., Dueck, Amylou C., and Hoffman, Ronald

Published
2022
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38. The day 100 score predicts moderate to severe cGVHD, transplant mortality, and survival after hematopoietic cell transplantation

Author

Metafuni, Elisabetta, Cavattoni, Irene Maria, Lamparelli, Teresa, Raiola, Anna Maria, Ghiso, Anna, Galaverna, Federica, Gualandi, Francesca, Di Grazia, Carmen, Dominietto, Alida, Varaldo, Riccardo, Signori, Alessio, Chiusolo, Patrizia, Sora', Federica, Giammarco, Sabrina, Laurenti, Luca, Sica, Simona, Angelucci, Emanuele, and Bacigalupo, Andrea

Published
2022
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43. Overall constitutive properties of stratified lattices with alternating chirality.

Author

Bacigalupo, Andrea, Badino, Paolo, Diana, Vito, and Gambarotta, Luigi

Subjects
*CHIRALITY, *MICROPOLAR elasticity, *METAMATERIALS, *LIGAMENTS, *CHIRALITY of nuclear particles
Abstract

The present research focuses on a continuum description of stratified metamaterials achieved through the superposition of layers with alternating chirality. Each layer is constructed as a periodic assembly of centre-symmetric periodic cells, formed by a recurring arrangement of rigid circular discs connected by elastic ligaments. The layers are interconnected through elastic pins passing through the centres of aligned discs, allowing for either restrained or free relative rotation. A micropolar continuum model is used to describe each individual layer. The overall response of the metamaterials to in-plane forces is derived using a multi-field non-local model, expressed in terms of the average and difference of displacement and rotational fields. The overall micropolar and standard (Cauchy) constitutive tensors have been determined in closed form. The validity of the equivalent generalized micropolar model has been confirmed through comparison with discrete Lagrangian solutions of representative examples. In addition, a detailed analysis of a pseudo-indentation test has been carried out. This article is part of the theme issue 'Current developments in elastic and acoustic metamaterials science (Part 2)'. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Dynamic continualization of mechanical metamaterials with quasi-periodic microstructure.

Author

Del Toro, Rosaria, De Bellis, Maria Laura, and Bacigalupo, Andrea

Subjects
TRANSFER matrix, FIBONACCI sequence, MICROSTRUCTURE, METAMATERIALS
Abstract

This article focuses on characterizing a class of quasi-periodic metamaterials created through the repeated arrangement of an elementary cell in a fixed direction. The elementary cell consists of two building blocks made of elastic materials and arranged according to the generalized Fibonacci sequence, giving rise to a quasi-periodic finite microstructure, also called Fibonacci generation. By exploiting the transfer matrix method, the frequency band structure of selected periodic approximants associated with the Fibonacci superlattice, i.e. the layered quasi-periodic metamaterial, is determined. The self-similarity of the frequency band structure is analysed by means of the invariants of the symplectic transfer matrix as well as the transmission coefficients of the finite clusters of Fibonacci generations. A high-frequency continualization scheme is then proposed to identify integral-type or gradient-type non-local continua. The frequency band structures obtained from the continualization scheme are compared with those derived from the Floquet–Bloch theory to validate the proposed scheme. This article is part of the theme issue 'Current developments in elastic and acoustic metamaterials science (Part 1).' [ABSTRACT FROM AUTHOR]

Published
2024
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45. Pure red cell aplasia among ABO mismatched hematopoietic stem cell transplant recipients: a 13-years retrospective study and literature review.

Author

Metafuni, Elisabetta, Busnego Barreto, Maria Teresa, Valentini, Caterina Giovanna, Giammarco, Sabrina, Limongiello, Maria Assunta, Sorà, Federica, Bianchi, Maria, Massini, Giuseppina, Piccirillo, Nicola, Putzulu, Rossana, Frioni, Filippo, Bacigalupo, Andrea, Teofili, Luciana, Chiusolo, Patrizia, and Sica, Simona

Subjects
PURE red cell aplasia, STEM cell transplantation, LITERATURE reviews, HEMATOPOIETIC stem cells, HEMATOPOIETIC stem cell transplantation, BLOOD group incompatibility, BONE marrow cells
Abstract

Background: Pure red cell aplasia (PRCA) is a possible complication after allogeneic hematopoietic stem cell transplantation (HSCT) with major ABO incompatibility. Patients experience delayed engraftment of the erythroid series, with prolonged transfusion-dependent anemia and iron overload. Methods: We performed a revision of the most recent literature about post-HSCT PRCA treatment procedures. Moreover, we conducted a retrospective study, over the last 13-years, which included all consecutive major ABO mismatched HSCT performed in our unit, with the aim to assess PRCA incidence, risk factors, and response to different treatments. Overall, 194 patients received a major ABO mismatched transplant from 2010 to 2022. For each patient, data about demographic and transplant characteristics, engraftment, blood transfusion, and possible treatment received were collected. Results: The literature review returned 23 eligible papers on PRCA treatment, with high success rate using plasma-exchange (PEX) and immunoadsorption procedures, daratumumab, and eltrombopag. Our study identified a total of 24 cases of PRCA. Among risk factors for PRCA development, we have found older recipient age (p=0.01), high pre-HSCT IgG and IgM IHA titer (p<0.0001), major rather than bidirectional ABO incompatibility (p=0.02), low T CD8 lymphocyte count in the graft (p=0.006), relative donor (p=0.02) and bone marrow as stem cell source (p=0.002). However, multivariate analysis confirmed only pre-HSCT IgG IHA titer as the unique risk factor for PRCA occurrence. The optimal cut-off value of pre-HSCT IgG IHA for PRCA development, resulted to be 1/64, with a 100% sensitivity and 68.8% specificity (p<0.0001). All patients with PRCA had received rhEPO and transfusion support and 20 patients received additional treatments like PEX, rituximab, and more recently daratumumab. Comprehensively, PEX and rituximab obtained a response in half of the cases, at a variable time, while the few cases of patients we treated with daratumumab suggest promising results. The overall response rate in our cohort was 75%, with significantly better survival (94.4% vs. 16.7%) and lower transplant-related mortality (6.3% vs. 80%) for PRCA responders. Conclusions: Standardized guidelines on when and how to treat PRCA are necessary because the current treatment is controversial among centers. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Autologous stem cell transplantation as bridging therapy followed by CD19 CAR-T cells in relapsed-refractory large B cell lymphoma

Author

Galli, Eugenio, Sorà, Federica, Hohaus, Stefan, Bellesi, Silvia, Autore, Francesco, Metafuni, Elisabetta, Innocenti, Idanna, Marra, John, Fresa, Alberto, Limongiello, Maria Assunta, Giammarco, Sabrina, Leccisotti, Lucia, Guarneri, Andrea, Chiusolo, Patrizia, Laurenti, Luca, Teofili, Luciana, Piccirillo, Nicola, Bacigalupo, Andrea, and Sica, Simona

Published
2022
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47. Special issues related to the diagnosis and management of acquired aplastic anemia in countries with restricted resources, a report on behalf of the Eastern Mediterranean blood and marrow transplantation (EMBMT) group and severe aplastic anemia working party of the European Society for blood and marrow transplantation (SAAWP of EBMT)

Author

Iftikhar, Raheel, Ahmad, Parvez, de Latour, Regis, Dufour, Carlo, Risitano, Antonio, Chaudhri, Naeem, Bazarbachi, Ali, De La Fuente, Josu, Höchsmann, Britta, Osman Ahmed, Syed, Gergis, Usama, Elhaddad, Alaa, Halkes, Constantijn, Albeirouti, Bassim, Alotaibi, Sultan, Kulasekararaj, Austin, Alzahrani, Hazzaa, Ben Othman, Tarek, Cesaro, Simone, Alahmari, Ali, Rihani, Rawad, Alshemmari, Salem, Hamidieh, Amir Ali, Bekadja, Mohamed-Amine, Passweg, Jakob, Al-Khabori, Murtadha, Rasheed, Walid, Bacigalupo, Andrea, Chaudhry, Qamar-Un-Nisa, Ljungman, Per, Marsh, Judith, El Fakih, Riad, and Aljurf, Mahmoud

Published
2021
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