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3. Common Components Framework (CCF) Enabled Intelligent Data Processing

Author

Varma, Sandeep, Shivam, Shivam, Masson, Anuj, Bhushanam, Apuroop, Banerjee, Ankita, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, and Arai, Kohei, editor

Published
2024
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4. Few-Shot Learning with Fine-Tuned Language Model for Suicidal Text Detection

Author

Varma, Sandeep, Shivam, Shivam, Ray, Biswarup, Banerjee, Ankita, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Kole, Dipak Kumar, editor, Roy Chowdhury, Shubhajit, editor, Basu, Subhadip, editor, Plewczynski, Dariusz, editor, and Bhattacharjee, Debotosh, editor

Published
2024
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7. COVID-19

Author

Mukherjee, Tathagata, primary, Banerjee, Ankita, additional, Mitra, Shweta, additional, and Mukherjee, Tirthankar, additional

Published
2022
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8. Contributors

Author

Abiodun, Gbenga Jacob, primary, Abiodun, Yekeen Abeeb, additional, Acharya, Anal, additional, Adegun, I.P., additional, Adenike, Sulaiman Faoziyat, additional, Adeniyi, Emmanuel Abidemi, additional, Adepetun, Akinola Oladiran, additional, Adzitey, F., additional, Afuye, Gbenga A., additional, Agbozo, Ebenezer, additional, Al-Hadlaq, Solaiman M., additional, Algamdi, Abdelmageed, additional, Allam, Zaheer, additional, Altinay, Zehra, additional, Altinay, Fahriye, additional, Ambrose, George Oche, additional, Anuradha, J., additional, Aqib, Amjad Islam, additional, Arun Kumar, K., additional, Auda, Sayed H., additional, Awotunde, Joseph Bamidele, additional, Aydinoglu, Ayse Tulay, additional, Babalola, O.T., additional, Bachate, Ravindra, additional, Bagalkoti, Vitthal T., additional, Balto, Hanan, additional, Bamidele, Akinfemi P., additional, Banerjee, Ankita, additional, Bhapkar, Haribhau, additional, Bharati, Subrato, additional, Bhat, M Sultan, additional, Bhattacharjee, Arup Kumar, additional, Bhoyar, Suraj, additional, Bicen, Huseyin, additional, Biradar, Balabhim Sankrappa, additional, Brika, Said Khalfa Mokhtar, additional, Busayo, Emmanuel T., additional, Celebi, Menil, additional, Cerkez, Yagmur, additional, Cevizoğlu, Mustafa Hulki, additional, Chaman, Sab M., additional, Chen, Fang, additional, Chergui, Khalil Ahmed, additional, Dagli, Gokmen, additional, Datta, Debabrata, additional, Deyasi, Arpan, additional, Durojaye, Olarewaju Ayodeji, additional, Ekundayo, Temitope C., additional, Ekundayo, Olapeju Y., additional, El-Ansary, Afaf, additional, Essien, Imaobong Sunday, additional, Farooq, Jasim, additional, Fayeun, L.S., additional, Gabriel, A.J., additional, Gaie, Christophe, additional, Gupta, Neeraj, additional, Gupta, Rashmi, additional, Haq, Amin Ul, additional, Hasan, Faraz, additional, Herron, Murray, additional, Ikpeme, Ekei V., additional, Johnson, O.V., additional, Jones, David S., additional, Joy, Deborah T., additional, Kalumba, Ahmed M., additional, Kanimozhi, V., additional, Kappi, Mallikarjun, additional, Karakuzu, Betul, additional, Khan, Asif, additional, Kızrak, M.A., additional, Kolawole, Paul Oluwatoba, additional, Kose, Utku, additional, Kushchu, Ibrahim, additional, Li, Jian Ping, additional, Makhija, Shubham, additional, Makinde, Olusola Samuel, additional, Makinde, O.S., additional, Marraiki, Najat, additional, Mattoo, Durdanah, additional, Memon, Imran, additional, Mihăit¸ă, Adriana-Simona, additional, Mir, Sajad Ahmad, additional, Mitra, Shweta, additional, Mohammed Harish, R., additional, Mohammed Harun Babu, R., additional, Mohanty, Aisworya, additional, Mondal, M. Rubaiyat Hossain, additional, Mueck, Markus, additional, Müftüoğlu, Z., additional, Mukherjee, Soumen, additional, Mukherjee, Tathagata, additional, Mukherjee, Tirthankar, additional, Mukhtar, Idris, additional, Musa, Adam Ahmed, additional, Muzammil, Iqra, additional, Muzmmal, Sidra, additional, Narang, Kabir, additional, Naseer, Muhammad Aamir, additional, Nasirzadeh, Farnad, additional, Nayak, Suvendu Chandan, additional, Nkechinyere, Ohanaka Judith, additional, Ogundokun, Roseline Oluwaseun, additional, Ogunleye, Timothy A., additional, Ojokoh, B.A., additional, Okoh, Anthony I., additional, Oksuz, Cemre, additional, Olaleye, Sunday Adewale, additional, Olamide, Adigun Temidayo, additional, Ololade, Olusola O., additional, Olusola-Makinde, Olubukola Olayemi, additional, Oluwaseun, Alakanse Suleiman, additional, Orimoloye, Israel R., additional, Oseni, Bamidele Mustapha, additional, Ou, Yuming, additional, Oznacar, Behcet, additional, Pachauri, Rupendra Kumar, additional, Pandey, Aditi, additional, Panigrahi, Chhabi Rani, additional, Parida, Sasmita, additional, Pati, Bibudhendu, additional, Pawar, Asha Mohandas, additional, Pawar, Mohandas V., additional, Podder, Prajoy, additional, Podder, Priya, additional, Rahla Rabia, M.P., additional, Rather, G.M., additional, Roös, Phillip B., additional, Rostemnezhad Cherati, Mozhdeh, additional, Sakalli Demirok, Mukaddes, additional, Salako, K.V., additional, Sarumi, O.A., additional, Sathish Kumar, D., additional, Shardoor, Nikhilkumar, additional, Sharma, Ashok, additional, Sharma, Mayank, additional, Shebana, M., additional, Sidiqui, Paras, additional, Singh, Jasdeep, additional, Singhal, Divya, additional, Solanki, Naishadh, additional, Tahir, Muhammad, additional, Taiwo, A.E., additional, Tanveer, Qaisar, additional, Tarim, E. Alperay, additional, Tekin, H. Cumhur, additional, Ubi, Godwin Michael, additional, Vardari, Luan, additional, Watat, Josue Kuika, additional, Yadav, Shivam, additional, Yıldırım, T., additional, and Yinka, Joel Ireoluwa, additional

Published
2022
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11. A PREVENTIVE TOOL FOR PREDICTING BLOODSTREAM INFECTIONS IN CHILDREN WITH BURNS

Author

Tsurumi, Amy, primary, Flaherty, Patrick J., additional, Que, Yok-Ai, additional, Ryan, Colleen M., additional, Banerjee, Ankita, additional, Chakraborty, Arijit, additional, Almpani, Marianna, additional, Shankar, Malavika, additional, Goverman, Jeremy, additional, Schulz, John T., additional, Sheridan, Robert L., additional, Friedstat, Jonathan, additional, Hickey, Sean A., additional, Tompkins, Ronald G., additional, and Rahme, Laurence G., additional

Published
2023
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16. List of contributors

Author

Acharya, Dhaval, Anavadiya, Bhavdip, Banerjee, Ankita, Bera, Jignasa H., Bhattacharya, Dipabarna, Bhori, Mustansir, Biswas, Soumyadip, Chakravarty, Damayanti, Chennakadan, Nimisha Joly, D'Lima, Lynn, Das, Anupriya, Das, Shreya, De, Ameyota, Denis, Sylvia, Dhar, Juhita, Dutta, Bandita, Elayaperumal, Sumitha, Francis, Andrea Mary, Gang, Sishir, Ganguli, Sayak, Ghosh, Sreejita, Ghosh, Upal Das, Ghosh, Sanjana, Goswami, Dweipayan, Hemalatha, C.R., Jobby, Renitta, Joseph, Natasha Mary, Jyoti Kindo, Anupma, Karmakar, Shreya, Kesarkar, Vaishnavi, Krishna Kumar, Ashok Kumar, Kumaraguru, Gowtham, Lahiri, Dibyajit, Malaiyandi, Jayanthi, Menon Kakkanattu, Yadhu Krishna, Mitra, Arup Kumar, Mohan, Nithyakalyani, Moorthy, Saruniyadevi, Mukherjee, Soumyadeep, Murthy, Karan Narasimha, Nag, Moupriya, Nishat Ahmed, Talaha, Panicker, Aravind, Patel, Dhara N., Phadke, Manju, Priyadarshini, Archana Jena, Raj A., Leyon Selvin, Rajasekharan, Satish Kumar, Ramachandran, Vidya, Ravichandran, Vinothkannan, Ray, Rina Rani, Roy, Drisha, Sabesan, Gokul Shankar, Sajal, Harshit, Samanta, Ashmita, Sam, Annie Jeyachristy, Saraf, Meenu, Shanmugam, Karthi, Sikkander, Shahitha, Sivamani, Yuvaraj, Sultana, Suhana, Sunder, Anusha, Tamba, Saichandana, Tungare, Kanchanlata, and Venkatesan, Nagasinduja

Published
2023
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17. Role of VapBC4 toxin-antitoxin system of Sulfolobus acidocaldarius in heat stress adaptation.

Author

Bhowmick A, Recalde A, Bhattacharyya C, Banerjee A, Das J, Rodriguez-Cruz UE, Albers S-V, and Ghosh A

Subjects
Heat-Shock Response, Archaeal Proteins genetics, Archaeal Proteins metabolism, Antitoxins genetics, Antitoxins metabolism, Hot Temperature, Gene Expression Regulation, Archaeal, Toxin-Antitoxin Systems genetics, Sulfolobus acidocaldarius genetics, Sulfolobus acidocaldarius metabolism, Sulfolobus acidocaldarius physiology
Abstract

Toxin-antitoxin (TA) systems are important for stress adaptation in prokaryotes, including persistence, antibiotic resistance, pathogenicity, and biofilm formation. Toxins can cause cell death, reversible growth stasis, and direct inhibition of crucial cellular processes through various mechanisms, while antitoxins neutralize the effects of toxins. In bacteria, these systems have been studied in detail, whereas their function in archaea remains elusive. During heat stress, the thermoacidophilic archaeon Sulfolobus acidocaldarius exhibited an increase in the expression of several bicistronic type II vapBC TA systems, with the highest expression observed in the vapBC4 system. In the current study, we performed a comprehensive biochemical characterization of the VapBC4 TA system, establishing it as a bonafide type II toxin-antitoxin system. The VapC4 toxin is shown to have high-temperature catalyzed RNase activity specific for mRNA and rRNA, while the VapB4 antitoxin inhibits the toxic activity of VapC4 by interacting with it. VapC4 toxin expression led to heat-induced persister-like cell formation, allowing the cell to cope with the stress. Furthermore, this study explored the impact of vapBC4 deletion on biofilm formation, whereby deletion of vapC4 led to increased biofilm formation, suggesting its role in regulating biofilm formation. Thus, during heat stress, the liberated VapC4 toxin in cells could potentially signal a preference for persister cell formation over biofilm growth. Thus, our findings shed light on the diverse roles of the VapC4 toxin in inhibiting translation, inducing persister cell formation, and regulating biofilm formation in S. acidocaldarius , enhancing our understanding of TA systems in archaea., Importance: This research enhances our knowledge of toxin-antitoxin (TA) systems in archaea, specifically in the thermoacidophilic archaeon Sulfolobus acidocaldarius . TA systems are widespread in both bacterial and archaeal genomes, indicating their evolutionary importance. However, their exact functions in archaeal cellular physiology are still not well understood. This study sheds light on the complex roles of TA systems and their critical involvement in archaeal stress adaptation, including persistence and biofilm formation. By focusing on S. acidocaldarius , which lives in habitats with fluctuating temperatures that can reach up to 90°C, the study reveals the unique challenges and survival mechanisms of this organism. The detailed biochemical analysis of the VapBC4 TA system, and its crucial role during heat stress, provides insights into how extremophiles can survive in harsh conditions. The findings of this study show the various functions of the VapC4 toxin, including inhibiting translation, inducing persister-like cell formation, and regulating biofilm formation. This knowledge improves our understanding of TA systems in thermoacidophiles and has broader implications for understanding how microorganisms adapt to extreme environments., Competing Interests: The authors declare no conflict of interest.

Published
2024
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