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Eine präoperativ bestehende Anämie, aber auch die perioperative Gabe von Erythrozytenkonzentraten sind eigenständige und unabhängige Risikofaktoren für das Auftreten postoperativer Komplikationen sowie erhöhter Sterblichkeit. Patient Blood Management (PBM) ist ein multidisziplinäres, evidenzbasiertes Konzept zur rechtzeitigen Erkennung und Behandlung von Anämien, zur Reduktion von Blutverlusten, zur Verringerung des Einsatzes von Bluttransfusionen und damit zur Reduktion gravierender Komplikationen (89–92). PBM wird sowohl von der Weltgesundheitsorganisation als auch der Deutschen Gesellschaft für Anästhesie und Intensivmedizin empfohlen und ist somit ein weltweit etabliertes Konzept (2, 3, 89, 90, 93–95). In dieser Arbeit wurde die Implementierung eines solchen PBM-Konzeptes mit Schwerpunkt der Anämiediagnostik sowie Therapie mittels intravenöser Eisensubstitution begleitet sowie die Auswirkung auf die perioperative Transfusionsrate untersucht.

This thoroughly revised and updated case-based book describes a variety of clinical scenarios in transfusion medicine likely to be encountered in a busy teaching hospital. It highlights the stream of clinical and laboratory data available to transfusionists, while reviewing the critical thinking required to lead the decision-making process towards accurate diagnosis and appropriate management.Transfusion Medicine: Case Studies and Clinical Management is a lively illustration of various clinical problems in transfusion medicine, including immune complications, microbiological problems, blood component use, apheresis techniques and management of complex situations, such as multiple trauma, sickle cell crisis and organ transplantation. Each case is carefully chosen and presented, with incorporated questions leading the reader towards solution of the problem in a logical and didactic manner. It is therefore essential reading for all medical and scientific professionals involved in managing transfusion, from hematologists to obstetricians, surgeons, intensivists and immunologists.

This book functions as a comprehensive and authoritative reference book in blood transfusion and blood substitutes. It is a collection of the latest developments and the newest investigations, and individual chapters are written by world experts in the arena. The book begins with a historical review on the practice of transfusions as well as the components and physiology of blood. The following chapters cover various topics, including platelet substitutes, hemoglobin-based oxygen carriers, perfluorocarbon based oxygen carriers, and safety issues related to artificial hemoglobin. All chapters provide a bulleted highlights list to facilitate readers in mastering the main points of each individual chapter. Blood Substitutes and Oxygen Biotherapeutics is an invaluable reference book for perioperative care providers, hematologists, anesthesiologists, surgeons, obstetricians and gynecologists.

ROSSI'S PRINCIPLES OF TRANSFUSION MEDICINE Transfusion Medicine impacts patients with hematologic, oncologic, and surgical conditions as well as all areas of critical care medicine and multiple areas of chronic care. This book aims to be the single best source for information related to any aspect or application of Transfusion Medicine. Contributors for the sixth edition have once again been drawn from various scientific, medical, and surgical disciplines. Thus, this book ranges from encouraging and managing donors, to collecting and preserving the blood, to matching it to the appropriate recipient, all the way to its clinical uses. It also extends these concepts to implantable tissue and regenerative medicine. Other sample topics covered within the work include: Contemporary issues in donation and transfusion: patient blood management, clinical and technical aspects of blood administration, and donor and patient Hemovigilance Blood components and derivatives: red blood cell metabolism, preservation and oxygen delivery, blood groups, and composition of plasma Apheresis, transplantation, and new therapies: hematopoietic growth factors, therapeutic phlebotomy and cellular apheresis, HLA antigens, alleles, and antibodies How Transfusion Medicine has been affected by the coronavirus pandemic, the role of pathogen reduction and other modern trends This book serves as a complete and comprehensive resource on Transfusion Medicine for clinicians who prescribe blood, students who expect to enter clinical practice, and for the scientists, physicians, nurses, technologists, and others who assure the quality and availability of blood services.

Practical Transfusion Medicine Practical Transfusion Medicine, Sixth Edition The pace of change in transfusion medicine is relentless, with new scientific and technological developments and continuing efforts to improve transfusion practice. This sixth edition of Practical Transfusion Medicine has been updated significantly to reflect the rapid changes in transfusion medicine since the fifth edition was published in 2017. The primary purpose of this edition remains the same as the first: to provide a comprehensive guide to transfusion medicine. This book contains more depth of information than standard handbooks on transfusion medicine, whilst being more concise and approachable than a standard reference text. This book covers the principles of transfusion medicine, the complications of transfusion, practice in blood centres and hospitals and clinical transfusion practice. This sixth edition includes a new section on patient blood management, cellular and tissue therapy, organ transplantation and the development of the evidence base for transfusion. It also features a new chapter on transfusion-associated circulatory overload to underline its importance as a complication of transfusion, and a reconfiguration of the section on clinical transfusion practice to allow consideration of the transfusion management of medical, surgical and haematology patients with and without bleeding. This sixth edition of Practical Transfusion Medicine provides accessible and comprehensive coverage of the field of transfusion medicine. It is a standalone text that will be useful to clinical and scientific staff: not only for trainees who require an overview of the field, but also for established practitioners who are involved in some aspect of transfusion medicine and require a comprehensive, accessible reference book.

Much has been published on heart health, kidney health, and gut health. But how many of us are aware of our blood health? Is your blood as healthy as it should be? How would you even know? Blood Works is a fascinating new blood owners'guide to help you care for the health of your most precious fluid—your blood.About 2 billion people globally are anemic, and almost as many suffer from iron deficiency without anemia. Many don't even know they have it, just feeling tired, lethargic, and “foggy-headed.” Sound familiar? Over 600 million more suffer from acute or sometimes unrecognized chronic blood loss from causes such as heavy menstrual bleeding, obstetric hemorrhage, gastrointestinal bleeding, surgery, and trauma. Anemia, iron deficiency, and bleeding are signs of “blood failure” and have major negative health effects. Blood Works, with contributions from 48 leading international medical experts, is a must have book for all who want to look after their blood health. Your blood is the essential fluid that keeps you alive. Yet, while many of us know our cholesterol level and blood pressure, few of us are aware of our blood count. What we don't know can affect our everyday quality of life and put us at risk if we have bleeding, an injury, or require hospitalization. Blood, and the vessels that contain it, make up the largest organ system in the body. Its balance and health must be maintained. For many decades, the treatment of first resort for anemia and blood loss has been blood transfusion, which is essentially a “liquid organ” transplant from another person. In heart failure or kidney failure, organ transplantation is not first-line treatment. In blood failure, blood “transplantation” should not be the first thing we reach for. Since the 1990s, scientific research has shown that the common use of blood transfusion is not the most effective treatment in many medical situations. It has been identified as one of the most overused treatments in modern medicine, costing billions of dollars, while causing changes in the recipient's immune system that may increase the risk of complications and death. In October 2021, the World Health Organization called for the urgent global implementation of Patient Blood Management (PBM), stating “our own blood is still the best thing to have in our veins.” Blood Works is one of the most exciting books on blood health you will read. The book zooms in on why medical experts from around the world now recognize the need for fundamental change in the way a patient's blood is managed. Known as PBM, Patient Blood Management places the person receiving treatment at the center of decisions involving their lifeblood. Its aim is to improve general health and treatment outcomes by managing and preserving a patient's own blood while empowering them to share in making decisions. Meticulously researched and referenced, masterfully illustrated, and featuring personal stories from patients and their families, Blood Works is a compelling read. It will have a profound impact on your health and the health of your loved ones and is an invaluable resource for health care professionals.