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Your search keyword '"Campos, Fabrício S."' showing total 8 results
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8 results on '"Campos, Fabrício S."'

2. Yellow Fever Virus Maintained by Sabethes Mosquitoes during the Dry Season in Cerrado, a Semiarid Region of Brazil, in 2021

Author

Oliveira, Cirilo H. de, primary, Andrade, Miguel S., additional, Campos, Fabrício S., additional, Cardoso, Jader da C., additional, Gonçalves-dos-Santos, Maria Eduarda, additional, Oliveira, Ramon Silva, additional, Aquino-Teixeira, Sandy Micaele, additional, Campos, Aline AS, additional, Almeida, Marco AB, additional, Simonini-Teixeira, Danilo, additional, Sevá, Anaiá da P., additional, Temponi, Andrea Oliveira Dias, additional, Magalhães, Fernando Maria, additional, Menezes, Agna Soares da Silva, additional, Lopes, Bartolomeu Teixeira, additional, Almeida, Hermes P., additional, Pedroso, Ana Lúcia, additional, Gonçalves, Giovani Pontel, additional, Chaves, Danielle Costa Capistrano, additional, Menezes, Givaldo Gomes de, additional, Bernal-Valle, Sofía, additional, Müller, Nicolas FD, additional, Janssen, Luis, additional, Santos, Edmilson dos, additional, Mares-Guia, Maria A., additional, Albuquerque, George R., additional, Romano, Alessandro PM, additional, Franco, Ana C., additional, Ribeiro, Bergmann M., additional, Roehe, Paulo M., additional, Lourenço-de-Oliveira, Ricardo, additional, and Abreu, Filipe Vieira Santos de, additional

Published
2023
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3. Evaluation of the anti-apoptotic activity of bovine alphaherpesvirus type 5 US3 protein kinase in insect cells using a recombinant baculovirus

Author

Silva, Alice M., Morgado, Fabrício S., Silva, Leonardo A., Borges, José R. J., Perecmanis, Simone, Ardisson-Araújo, Daniel M. P., Ribeiro, Bergmann M., and Campos, Fabrício S.

Abstract

Bovine alphaherpesvirustype 5 (BoHV-5) is one of the main agents responsible for meningoencephalitis in cattle in Brazil, causing significant economic losses. It is known that other viruses of the Herpesviridaefamily such as Bovine alphaherpesvirustype 1, Swine alphaherpesvirustype 1, and the Human alphaherpesvirustypes 1 and 2 encode genes homologous to BoHV-5, with recognized action in the control of apoptosis. The objective of this work was to express the BoHV-5 US3 gene in a baculovirus-based expression system for the production of the serine/threonine kinase protein and to evaluate its activity in the control of apoptosis in vitro. A recombinant baculovirus derived from the Autographa californica multiple nucleopolyhedrovirus(AcMNPV) containing the US3 gene and a deletion in the baculovirus anti-apoptotic p35gene was constructed using the Bac-to-Bac™ system. This recombinant baculovirus was used to evaluate the anti-apoptotic activity of the recombinant US3 protein in insect cells comparing with two other AcMNPV recombinants, one containing a functional copy of the AcMNPV anti-apoptotic p35gene and an AcMNPV p35knockout virus with the anti-apoptotic iap-3gene from Anticarsia gemmatalis multiple nucleopolyhedrovirus (AgMNPV). We found that the caspase level was higher in insect cells infected with the US3-contanining recombinant virus than in cells infected with the AcMNPV recombinants containing the p35and iap-3genes. These results indicate that the BoHV-5 US3 protein kinase gene is not able to block apoptosis in insect cells induced by the infection of a p35knockout AcMNPV.

Published
2024
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4. Yellow Fever Virus Maintained by Sabethes Mosquitoes during the Dry Season in Cerrado, a Semiarid Region of Brazil, in 2021.

Author

de Oliveira, Cirilo H., Andrade, Miguel S., Campos, Fabrício S., da C. Cardoso, Jader, Gonçalves-dos-Santos, Maria Eduarda, Oliveira, Ramon Silva, Aquino-Teixeira, Sandy Micaele, Campos, Aline AS, Almeida, Marco AB, Simonini-Teixeira, Danilo, da P. Sevá, Anaiá, Temponi, Andrea Oliveira Dias, Magalhães, Fernando Maria, da Silva Menezes, Agna Soares, Lopes, Bartolomeu Teixeira, Almeida, Hermes P., Pedroso, Ana Lúcia, Gonçalves, Giovani Pontel, Chaves, Danielle Costa Capistrano, and de Menezes, Givaldo Gomes

Subjects
YELLOW fever, CERRADOS, PHYTOPLASMAS, MOSQUITOES, WEATHER, PHYLOGEOGRAPHY, ARID regions
Abstract

In recent decades, waves of yellow fever virus (YFV) from the Amazon Rainforest have spread and caused outbreaks in other regions of Brazil, including the Cerrado, a savannah-like biome through which YFV usually moves before arriving at the Atlantic Forest. To identify the vectors involved in the maintenance of the virus in semiarid environments, an entomological survey was conducted after confirmation of yellow fever (YF) epizootics at the peak of the dry season in the Cerrado areas of the state of Minas Gerais. In total, 917 mosquitoes from 13 taxa were collected and tested for the presence of YFV. Interestingly, mosquitoes of the Sabethes genus represented 95% of the diurnal captured specimens, displaying a peak of biting activity never previously recorded, between 4:30 and 5:30 p.m. Molecular analysis identified three YFV-positive pools, two from Sabethes chloropterus—from which near-complete genomes were generated—and one from Sa. albiprivus, whose low viral load prevented sequencing. Sa. chloropterus was considered the primary vector due to the high number of copies of YFV RNA and the high relative abundance detected. Its bionomic characteristics allow its survival in dry places and dry time periods. For the first time in Brazil, Sa. albiprivus was found to be naturally infected with YFV and may have played a role as a secondary vector. Despite its high relative abundance, fewer copies of viral RNA were found, as well as a lower Minimum Infection Rate (MIR). Genomic and phylogeographic analysis showed that the virus clustered in the sub-lineage YFVPA-MG, which circulated in Pará in 2017 and then spread into other regions of the country. The results reported here contribute to the understanding of the epidemiology and mechanisms of YFV dispersion and maintenance, especially in adverse weather conditions. The intense viral circulation, even outside the seasonal period, increases the importance of surveillance and YFV vaccination to protect human populations in affected areas. [ABSTRACT FROM AUTHOR]

Published
2023
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5. Complete Genome Sequences of Two Bovine Alphaherpesvirus 5 Subtype C Strains from Southeast Brazil

Author

Paim, Willian P., primary, Campos, Fabrício S., additional, Cibulski, Samuel P., additional, Scheffer, Camila M., additional, Tochetto, Caroline, additional, Varela, Ana P. M., additional, Junqueira, Dennis M., additional, Mayer, Fabiana Q., additional, Romijn, Phyllis C., additional, Pituco, Edviges M., additional, Franco, Ana C., additional, Spilki, Fernando R., additional, and Roehe, Paulo M., additional

Published
2022
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6. Fast surveillance response and genome sequencing reveal the circulation of a new Yellow Fever Virus sublineage in 2021, in Minas Gerais, Brazil

Author

Andrade, Miguel S., primary, Campos, Fabrício S., additional, de Oliveira, Cirilo H., additional, Oliveira, Ramon Silva, additional, Campos, Aline A. S., additional, Almeida, Marco A. B., additional, Simonini-Teixeira, Danilo, additional, Sevá, Anaiá da P., additional, Temponi, Andrea Oliveira Dias, additional, Magalhães, Fernando Maria, additional, Chaves, Danielle Costa Capistrano, additional, Pereira, Maira Alves, additional, Lamounier, Ludmila Oliveira, additional, de Menezes, Givaldo Gomes, additional, Teixeira, Sandy Micaele Aquino, additional, dos Santos, Maria Eduarda Gonçalves, additional, Bernal-Valle, Sofía, additional, Müller, Nicolas F. D., additional, Cardoso, Jader da C., additional, dos Santos, Edmilson, additional, Mares-Guia, Maria A., additional, Albuquerque, George R., additional, Romano, Alessandro P. M., additional, Franco, Ana C., additional, Ribeiro, Bergmann M., additional, Roehe, Paulo M., additional, and Abreu, Filipe V. S., additional

Published
2021
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7. Identification of potential new mosquito-associated viruses of adult Aedes aegypti mosquitoes from Tocantins state, Brazil

Author

Duarte, Matheus A., primary, Campos, Fabrício S., additional, Araújo Neto, Osvaldo F., additional, Silva, Leonardo A., additional, Silva, Arthur B., additional, Aguiar, Thalita C., additional, Santos, Raissa N., additional, Souza, Ueric J. B., additional, Alves, Giselly B., additional, Melo, Fernando L., additional, Ardisson-Araujo, Daniel M. P., additional, Aguiar, Raimundo W. S., additional, and Ribeiro, Bergmann M., additional

Published
2021
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8. Real-Time Genomic Surveillance during the 2021 Re-Emergence of the Yellow Fever Virus in Rio Grande do Sul State, Brazil

Author

Andrade, Miguel de S., primary, Campos, Fabrício S., additional, Campos, Aline A. S., additional, Abreu, Filipe V. S., additional, Melo, Fernando L., additional, Sevá, Anaiá da P., additional, Cardoso, Jader da C., additional, Dos Santos, Edmilson, additional, Born, Lucas C., additional, Silva, Cláudia M. D. da, additional, Müller, Nicolas F. D., additional, Oliveira, Cirilo H. de, additional, Silva, Alex J. J. da, additional, Simonini-Teixeira, Danilo, additional, Bernal-Valle, Sofía, additional, Mares-Guia, Maria A. M. M., additional, Albuquerque, George R., additional, Romano, Alessandro P. M., additional, Franco, Ana C., additional, Ribeiro, Bergmann M., additional, Roehe, Paulo M., additional, and Almeida, Marco A. B. de, additional

Published
2021
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