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In order to effectively utilize the tidal current energy in offshore wind farms, a swing oscillating hydrofoil system for tidal current energy capture is proposed. The system is constructed with oscillating hydrofoils as tidal current energy capture device combined with offshore wind turbine underwater tower. Lattice Boltzmann method and large eddy simulation method were combined, and the hydrodynamic characteristics and energy collection efficiency of a NACA0015 airfoil with different motion parameters were numerically analyzed with or without the influence of tower wake. The influence of pitch amplitude, heave amplitude and chord length of the hydrofoil on the energy collection efficiency of the system is analyzed from the aspect of vortex structure in the moving process. The results show that the energy collection efficiency of the oscillating wing is significantly improved by the trailing vortex of the tower, and the vortex shedding behind the tower can reduced by the addition of the oscillating wing, consequently, the fatigue load caused by the flow around the cylindrical body can be reduced. The energy capture efficiency of the oscillating wing can reach a highest efficiently of 30.72% in the wake vortex region of the tower, which has obvious advantages compared with the traditional oscillating wing tidal current energy capture device, and provides an effective way to improve the overall energy utilization rate of offshore wind farms.

Purpose: To explore the effects of the tight junction protein zonula occludens 1 (ZO-1) on experimental corneal neovascularization (CNV). Methods: CNV models were established in the left eyes of BALB/c mice using NaOH. Anti-ZO-1 neutralizing antibody was topically applied to the burnt corneas after modeling thrice a day for 1 week. CD31 expression was analyzed to calculate the ratio of CNV number to area using a corneal whole-mount fluorescent immunohistochemical assay. Messenger ribonucleic acid (mRNA) and protein expression levels of ZO-1, vascular endothelial growth factor (VEGF), interleukin (IL)-1β, IL-6, IL-8, IL-18, monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor alpha (TNF-α), phosphorylated protein kinase C (pPKC), and clusterin in burned corneas were detected by reverse transcriptase polymerase chain reaction (PCR) and western blot analyses. Infiltration of neutrophils, macrophages, and progenitor cells was examined by flow cytometry. Results: CNV was obviously greater in 45 s than in 15 s alkali injury group. In another experiment, CNV was obviously greater in the ZO-1 antibody group than in the vehicle-treated group. Corneal mRNA and protein expression levels of VEGF, IL-1β, IL-6, IL-8, IL-18, and MCP-1 were significantly higher in the ZO-1 antibody group than in the control group. Infiltration of neutrophils, macrophages, and progenitor cells was significantly greater in the ZO-1 antibody group than in the control group. TNF-α expression was much higher in 45 s than in 15 s alkali injury group. However, protein expression of pPKC and clusterin was much lower in 45 s than in 15 s alkali injury group. Conclusions: Anti-ZO-1 neutralizing antibody-treated mice exhibited enhanced alkali-induced CNV through enhanced intracorneal infiltration of progenitor and inflammatory cells. [ABSTRACT FROM AUTHOR]