47 results on '"Chee, Soon Phaik"'
Search Results
2. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 2—global current practice patterns for the management of Cytomegalovirus anterior uveitis
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Thng, Zheng Xian, Putera, Ikhwanuliman, Testi, Ilaria, Chan, Kevin, Westcott, Mark, Chee, Soon-Phaik, Dick, Andrew D., Kempen, John H., Bodaghi, Bahram, Thorne, Jennifer E., Barisani-Asenbauer, Talin, de Smet, Marc D., Smith, Justine R., McCluskey, Peter, La Distia Nora, Rina, Jabs, Douglas A., de Boer, Joke H., Sen, H. Nida, Goldstein, Debra A., Khairallah, Moncef, Davis, Janet L., Rosenbaum, James T., Jones, Nicholas P., Nguyen, Quan Dong, Pavesio, Carlos, Agrawal, Rupesh, and Gupta, Vishali
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- 2024
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3. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 1—global current practice patterns for the management of Herpes Simplex Virus and Varicella Zoster Virus anterior uveitis
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Thng, Zheng Xian, Putera, Ikhwanuliman, Testi, Ilaria, Chan, Kevin, Westcott, Mark, Chee, Soon-Phaik, Dick, Andrew D., Kempen, John H., Bodaghi, Bahram, Thorne, Jennifer E., Barisani-Asenbauer, Talin, de Smet, Marc D., Smith, Justine R., McCluskey, Peter, La Distia Nora, Rina, Jabs, Douglas A., de Boer, Joke H., Sen, H. Nida, Goldstein, Debra A., Khairallah, Moncef, Davis, Janet L., Rosenbaum, James T., Jones, Nicholas P., Nguyen, Quan Dong, Pavesio, Carlos, Agrawal, Rupesh, and Gupta, Vishali
- Published
- 2024
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4. The Humira in Ocular Inflammations Taper (HOT) Study
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Pichi, Francesco, Smith, Scott D., Goldstein, Debra A., Baddar, Dina, Gerges, Terese K.A., Janetos, Timothy M., Ruiz-Cruz, Matilde, Elena Concha-del-Río, Luz, Maruyama, Kazuichi, Carina ten Berge, Josianne, Rombach, Saskia M., Cimino, Luca, Bolletta, Elena, Miserocchi, Elisabetta, Scandale, Pierluigi, Serafino, Massimiliano, Camicione, Paola, Androudi, Sofia, Gonzalez-Lopez, Julio J., Lim, Lyndell L., Singh, Nandini, Gupta, Vishali, Gupta, Nikita, Amer, Radgonde, Dodds, Emilio M., Inchauspe, Sebastian, Munk, Marion R., Donicova, Emilia, Carreño, Ester, Takeuchi, Masaru, Chee, Soon-Phaik, Chew, Milton C., Agarwal, Aniruddha, Schlaen, Ariel, Gómez, Ramiro A., Couto, Cristobal A., Khairallah, Moncef, and Neri, Piergiorgio
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- 2024
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5. Antiviral treatment for acute retinal necrosis: A systematic review and meta-analysis
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Putera, Ikhwanuliman, Ridwan, Asri Salima, Dewi, Metta, Cifuentes-González, Carlos, Rojas-Carabali, William, Sitompul, Ratna, Edwar, Lukman, Susiyanti, Made, Aziza, Yulia, Pavesio, Carlos, Chee, Soon-Phaik, Mahendradas, Padmamalini, Biswas, Jyotirmay, Kempen, John H., Gupta, Vishali, de-la-Torre, Alejandra, La Distia Nora, Rina, and Agrawal, Rupesh
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- 2024
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6. Presentation, Diagnostic Testing and Initial Treatment of Vitreoretinal Lymphoma
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Androudi, Sofia, Apivatthakakul, Atitaya, Arevalo, Fernando J., Berkenstock, Meghan K., Carreño, Ester, Chee, Soon-Phaik, Choovuthayakorn, Janejit, Cimino, Luca, Cornish, Elisa E., Farrall, Alexandra L., Gehl, Zsuzsanna, Gentile, Pietro, Gerges, Terese K., Gozzi, Fabrizio, Hernández-Pons, Antonio, Issa, Samar, Kim, Hyeong Min, Kim, Min, Knickelbein, Jared E., Kunavisarut, Paradee, Lee, Seung M., Lim, Lyndell L., Lin, Ming Lee, Llorenç, Victor, López-Sierra, Sara, Martínez-Costa, Lucía, McCluskey, Peter, Mochizuki, Manabu, O'Day, Roderick F., Pai, Amy S., Palestine, Alan G., Pathanapitoon, Kessara, Radford, Mark H.B., Silpa-Archa, Sukhum, Smith, Justine R., Terada, Yukiko, Waduthantri, Samanthila, Weaver, Travers R.E., Williams, Keryn L., Woo, Se Joon, and Younan, Christine
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- 2024
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7. Pan-viral Antibody Repertoire of Aqueous Humor in Cytomegalovirus Uveitis
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Tiu, Charles Kevin, primary, Chia, Wan Ni, additional, Anderson, Danielle E, additional, Chee, Soon-Phaik, additional, Wang, Lin-Fa, additional, and Siak, Jay, additional
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- 2024
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8. Severely subluxated cataract
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Chee, Soon-Phaik, primary, McKee, Yuri, additional, Snyder, Michael E., additional, Lockington, David, additional, Vasavada, Abhay, additional, Vasavada, Vaishali, additional, Daoud, Yassine J., additional, Rodgers, Emily Grace, additional, and Al-Mohtaseb, Zaina, additional
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- 2024
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9. The Eye of the Storm: COVID-19 Vaccination and the Eye
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Ng, Xin Le, Betzler, Bjorn Kaijun, Ng, Sean, Chee, Soon Phaik, Rajamani, Lakshminarayanan, Singhal, Amit, Rousselot, Andres, Pavesio, Carlos E., Gupta, Vishali, de Smet, Marc D., and Agrawal, Rupesh
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- 2022
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10. Successful treatment of psoriasis-associated uveitis with ixekizumab after failure of secukinumab and risankizumab
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Lua, Angelyn Chen Yin, primary, Chee, Soon-Phaik, additional, and Oon, Hazel Hwee Boon, additional
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- 2024
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11. Capsular phimosis with intraocular lens tilt and decentration
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Chee, Soon-Phaik, primary, Dick, H. Burkhard, additional, Masket, Samuel, additional, Beltz, Jacqueline, additional, Vajpayee, Rasik B., additional, Yeu, Elizabeth, additional, and Zhu, Dagny, additional
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- 2023
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12. Response to “Observations on the association between Obstructive Sleep Apnea and Floppy Eyelid Syndrome: A systematic review and meta-analysis”
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Cheong, Alex Jia Yang, primary, Ho, Owen Tsung Wen, additional, Wang, Sean Kang Xuan, additional, Woon, Chang Yi, additional, See, Anna, additional, Ng, Adele Chin Wei, additional, Loh, Shaun Ray Han, additional, Chee, Soon-Phaik, additional, and Toh, Song Tar, additional
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- 2023
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13. Ultrasound biomicroscopy in the management of complex cataract and intraocular lens: A review.
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Chan, Nicole S.W., Lim, Jane S., Mohanram, Lakshmanasamudram S., and Chee, Soon‐Phaik
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ACOUSTIC microscopy ,INTRAOCULAR lenses ,PARS plana ,CILIARY body ,CATARACT - Abstract
Ultrasound biomicroscopy (UBM) is an invaluable investigation for imaging anterior segment structures. Although it is operator‐dependent and time consuming, unlike optical‐based imaging techniques, it is able to image structures posterior to the iris, such as the zonules, ciliary body and part of the pars plana. It is especially useful in advanced cataracts, traumatic cataracts, subluxed lenses, posterior polar cataracts, and congenital and developmental anomalies affecting the anterior segment. It provides diagnostic information in eyes with complex cataracts or intraocular lens (IOL)‐related pathology, and aids in surgical planning in order to minimise complications. In this review, we describe the UBM features of various lenticular pathologies and demonstrate its application in the diagnosis and surgical management of lens and IOL‐related pathologies. [ABSTRACT FROM AUTHOR]
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- 2024
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14. THE HUMIRA IN OCULAR INFLAMMATIONS TAPER (HOT) STUDY
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Pichi, Francesco, primary, Smith, Scott D, additional, Goldstein, Debra A, additional, Baddar, Dina, additional, Gerges, Terese K A, additional, Janetos, Timothy M, additional, Ruiz-Cruz, Matilde, additional, Concha-del-Río, Luz Elena, additional, Maruyama, Kazuichi, additional, Carina ten Berge, Josianne, additional, Rombach, Saskia M, additional, Cimino, Luca, additional, Bolletta, Elena, additional, Miserocchi, Elisabetta, additional, Scandale, Pierluigi, additional, Serafino, Massimiliano, additional, Camicione, Paola, additional, Androudi, Sofia, additional, Gonzalez-Lopez, Julio J, additional, Lim, Lyndell L., additional, Singh, Nandini, additional, Gupta, Vishali, additional, Gupta, Nikita, additional, Amer, Radgonde, additional, MD, Emilio M Dodds, additional, MD, Sebastian Inchauspe, additional, Munk, Marion R, additional, Donicova, Emilia, additional, Carreño, Ester, additional, Takeuchi, Masaru, additional, Chee, Soon-Phaik, additional, Chew, Milton C, additional, Agarwal, Aniruddha, additional, Schlaen, Ariel, additional, Gómez, Ramiro A, additional, Couto, Cristobal A., additional, Khairallah, Moncef, additional, and Neri, Piergiorgio, additional
- Published
- 2023
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- View/download PDF
15. Antiviral treatment for acute retinal necrosis: A systematic review and meta-analysis
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Putera, Ikhwanuliman, primary, Ridwan, Asri Salima, additional, Dewi, Metta, additional, Cifuentes-González, Carlos, additional, Rojas-Carabali, William, additional, Sitompul, Ratna, additional, Edwar, Lukman, additional, Susiyanti, Made, additional, Aziza, Yulia, additional, Pavesio, Carlos, additional, Chee, Soon-Phaik, additional, Mahendradas, Padmamalini, additional, Biswas, Jyotirmay, additional, Kempen, John H., additional, Gupta, Vishali, additional, de-la-Torre, Alejandra, additional, Nora, Rina La Distia, additional, and Agrawal, Rupesh, additional
- Published
- 2023
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16. Risk factors affecting visual outcomes following dropped nucleus after cataract surgery
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Hu, Jeremy Youwei, primary, Ti, Seng-Ei, additional, and Chee, Soon-Phaik, additional
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- 2023
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17. Approach to a spontaneously ruptured posterior polar cataract
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Chee, Soon-Phaik, primary, Ayres, Brandon D., additional, Lee, Mun Wai, additional, Vasavada, Vaishali, additional, Fram, Nicole R., additional, and Srinivasan, Sathish, additional
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- 2023
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18. Risk factors affecting visual outcomes following dropped nucleus after cataract surgery
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Hu, Jeremy Youwei, Ti, Seng-Ei, and Chee, Soon-Phaik
- Abstract
Background/ Aims: To describe the visual outcomes in eyes with dropped nucleus during phacoemulsification surgery. Setting: Singapore National Eye Centre (SNEC). Design: Retrospective chart review of prospectively reported cases of dropped nucleus. Methods: The clinical charts of all cases of dropped nucleus (Jan 2001 to Dec 2016) were retrospectively reviewed for patient demographics, surgeon type, stage of surgery, timing of pars plana vitrectomy (PPV), and complications. Visual success was defined as best corrected visual acuity (BCVA) ≥ 20/40 at last review. Final risk factors affecting visual success were identified using multivariate logistic regression analysis. Results: Incidence of dropped nucleus following cataract surgery was 0.17% (n= 292). Duration of follow-up was 25.5 months (mean), 18.5 months (median). There was a statistically significant difference in dropped nucleus rate between Residents (0.3%) and Faculty (0.14%) (x
2 = 38.2, P< 0.001), but ensuing major complications rates were similar. PPV was performed in 251 eyes (87.2%). At final examination, 202 cases (85.2%) achieved BCVA 20/40 or better, after excluding patients with co-existing ocular pathology. Timing of vitrectomy (delayed vs same-day) did not influence the final visual success (x2 = 0.969, p= 0.51). Risk factors for poor visual outcomes included age >70 years, absence of intraocular lens (IOL) implant, and presence of major complications. Conclusion: Overall incidence of dropped nucleus in SNEC was 0.17%, with BCVA of 20/40 or better in 85.2% cases. Visual prognosis was influenced by patient’s age, presence of IOL implant or additional major complications.- Published
- 2024
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19. Association between obstructive sleep apnea and floppy eyelid syndrome: A systematic review and metaanalysis
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Cheong, Alex Jia Yang, primary, Ho, Owen Tsung Wen, additional, Wang, Sean Kang Xuan, additional, Woon, Chang Yi, additional, Yap, Kihan, additional, Ng, Kevin Joo Yang, additional, Xu, Flora Wen Xin, additional, See, Anna, additional, Ng, Adele Chin Wei, additional, Loh, Shaun Ray Han, additional, Chee, Soon-Phaik, additional, and Toh, Song Tar, additional
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- 2023
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20. Surgical decisions in the setting of zonulopathy
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Fram, Nicole R., primary, McKee, Yuri, additional, Chang, David F., additional, Chee, Soon-Phaik, additional, Donaldson, Kendall E., additional, Crandall, David A., additional, Al-Mohtaseb, Zaina, additional, and Chen, Allison J., additional
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- 2023
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21. Infectious Uveitis: Conversations with the Experts.
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Agrawal, Rupesh, Thng, Zheng Xian, Gupta, Amod, Toy, Brian C., Dick, Andrew D., Smith, Justine R., Chee, Soon-Phaik, Gupta, Vishali, and Rao, Narsing A.
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IRIDOCYCLITIS ,UVEITIS ,POSTERIOR segment (Eye) ,NUCLEOTIDE sequencing ,IDIOPATHIC thrombocytopenic purpura ,GENE expression - Abstract
Isolated ocular infections that currently require systemic therapy or prophylaxis, such as viral infections, toxoplasmosis, and certain cases of tuberculous uveitis for example, would greatly benefit from long-lasting local drug delivery systems. Local ocular therapies nevertheless can play a role in patients who are unable to tolerate systemic treatment (i.e., pancytopenia as a side effect of ganciclovir treatment). In general, if I see a role for anti-inflammatory treatment with systemic prednisolone - for example, in toxoplasmic retinochoroiditis - I like to see a response to the antimicrobial drug(s) or at least allow time for antimicrobial therapy to have had sufficient time to take effect before starting prednisolone, and I watch carefully to ensure there is no progression after starting this agent. B SPC b :Generally, I prefer to start the antimicrobial therapy 48-72 hours ahead of the corticosteroid/immunomodulatory therapy to allow time for the former to take effect. In a nutshell, sometimes stop the current treatment, re-analyse the case for potential differentials that might have been overlooked, and if none, then start appropriately and slowly increase immunosuppressive therapy (under cover of antimicrobials). B AG b :Traditionally, CMV retinitis was seen in patients with HIV infection and manifested as a perivascular chronic retinitis that progressed rather slowly and was accompanied by minimal anterior chamber or vitreous reaction. [Extracted from the article]
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- 2023
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22. Ocular Toxoplasmosis.
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Goh, Eunice Jin Hui, Putera, Ikhwanuliman, La Distia Nora, Rina, Mahendradas, Padmamalini, Biswas, Jyotirmay, Chee, Soon-Phaik, Testi, Ilaria, Pavesio, Carlos E, Curi, Andre Luiz Land, Vasconcelos-Santos, Daniel Vitor, Arora, Atul, Gupta, Vishali, de-la-Torre, Alejandra, and Agrawal, Rupesh
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TOXOPLASMOSIS ,IRIDOCYCLITIS ,VISION disorders ,LITERARY sources ,AGE groups ,UVEITIS - Abstract
Introduction: Ocular toxoplasmosis is the leading cause of posterior uveitis worldwide, affecting individuals acrossdifferent age groups. The key to reducing vision loss includes prompt diagnosis and treatment. However, despite the prevalence of ocular toxoplasmosis, there has been little consensus regarding its pathophysiology,clinical features, diagnosis, and especially management. Methods: The data sources were literature reviews, including Pub Med and Medline databases. Search terms included toxoplasmosis, retinitis, vasculitis, vitritis, uveitis alone or in combination with, serum, aqueous, vitreous eye, ocular and review. Results: In this review paper, we have sought to provide an overview of the pathophysiology, epidemiology, and clinical features of the disease, both based on current literature and our own clinical experience. We have also discussed the use of serology, ocular fluid, and ophthalmic investigations that could further facilitate the diagnosis of ocular toxoplasmosis.Different management strategies have been reported worldwide, including newer approaches such as local therapy. Conclusion: A better understanding of critical aspects of ocular toxoplasmosis will hopefully lead to reduced morbidity, including blindness associated with this condition. [ABSTRACT FROM AUTHOR]
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- 2023
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23. Infectious Uveitis: Conversations with the Experts
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Agrawal, Rupesh, primary, Thng, Zheng Xian, additional, Gupta, Amod, additional, Toy, Brian C., additional, Dick, Andrew D., additional, Smith, Justine R, additional, Chee, Soon-Phaik, additional, Gupta, Vishali, additional, and Rao, Narsing A., additional
- Published
- 2022
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24. Ocular Toxoplasmosis
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Goh, Eunice Jin Hui, primary, Putera, Ikhwanuliman, additional, La Distia Nora, Rina, additional, Mahendradas, Padmamalini, additional, Biswas, Jyotirmay, additional, Chee, Soon-Phaik, additional, Testi, Ilaria, additional, Pavesio, Carlos E, additional, Curi, Andre Luiz Land, additional, Vasconcelos-Santos, Daniel Vitor, additional, Arora, Atul, additional, Gupta, Vishali, additional, de-la-Torre, Alejandra, additional, and Agrawal, Rupesh, additional
- Published
- 2022
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25. Clinical characteristics and treatment outcomes of cytomegalovirus anterior uveitis and endotheliitis: A systematic review and meta-analysis
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La Distia Nora, Rina, primary, Putera, Ikhwanuliman, additional, Mayasari, Yuri Dwi, additional, Hikmahwati, Wandya, additional, Pertiwi, Adinda Mulya, additional, Ridwan, Asri Salima, additional, Sitompul, Ratna, additional, Westcott, Mark, additional, Chee, Soon-Phaik, additional, Pavesio, Carlos, additional, Thng, Zheng Xian, additional, Gupta, Vishali, additional, and Agrawal, Rupesh, additional
- Published
- 2022
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26. Response to “Observations on the association between obstructive sleep apnea and floppy eyelid syndrome: A systematic review and meta-analysis”
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Cheong, Alex Jia Yang, Ho, Owen Tsung Wen, Wang, Sean Kang Xuan, Woon, Chang Yi, See, Anna, Ng, Adele Chin Wei, Loh, Shaun Ray Han, Chee, Soon-Phaik, and Toh, Song Tar
- Published
- 2024
- Full Text
- View/download PDF
27. The Eye of the Storm: COVID-19 Vaccination and the Eye
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Ng, Xin Le, primary, Betzler, Bjorn Kaijun, additional, Ng, Sean, additional, Chee, Soon Phaik, additional, Rajamani, Lakshminarayanan, additional, Singhal, Amit, additional, Rousselot, Andres, additional, Pavesio, Carlos E., additional, Gupta, Vishali, additional, de Smet, Marc D., additional, and Agrawal, Rupesh, additional
- Published
- 2021
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28. Candida Endophthalmitis Treated Successfully With Isavuconazole: A Case Report
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Sng, Edwin Chong Yu, primary, Tan, Ai Ling, additional, Zhou, Peijun Yvonne, additional, Tan, Tira J, additional, Waduthantri, Samanthila, additional, Chee, Soon-Phaik, additional, and Tan, Ban Hock, additional
- Published
- 2021
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29. Pediatric Uveitis and Scleritis in a Multi-Ethnic Asian Population.
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Waduthantri, Samanthila, Chee, Soon-Phaik, Waduthantri, Samanthila , MS (Ophth), and Chee, Soon-Phaik , FRCOphth
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IRIDOCYCLITIS , *ASIANS , *SCLERITIS , *UVEITIS , *JUVENILE idiopathic arthritis , *EYE care - Abstract
Purpose: To describe the demographics and clinical characteristics of pediatric uveitis and scleritis at a tertiary eye care center.Methods: Clinical records of children with either uveitis or scleritis that presented between January 1989 and January 2016 were reviewed retrospectively.Results: Seventy-three patients were identified. Fifty-four had uveitis and 19 had scleritis. Posterior uveitis was the most common (27.8%), followed by intermediate uveitis (25.9%), panuveitis (25.9%) and anterior uveitis. Majority were noninfectious uveitis (37.0%), and 29.6% were idiopathic. Common associations were sarcoidosis (14.8%), HLA-B27 haplotype (9.3%) and toxoplasmosis (7.4%). Posterior scleritis was more common (94.7%) than anterior scleritis and majority were idiopathic (68.4%). Delayed patient presentation and presenting visual acuity worse than 0.3 LogMAR were associated with poor visual outcome (p = .03; OR = 0.17; 95% CI, 0.03-0.84 and p = .007; OR = 0.09; 95% CI, 0.02-0.52 respectively).Conclusion: Majority had noninfectious etiologies. Uveitis associated with juvenile idiopathic arthritis was rare. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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30. Randomized Controlled Trial Comparing Femtosecond Laser-Assisted with Conventional Phacoemulsification on Dense Cataracts
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Chee, Soon-Phaik, primary, Yang, Younian, additional, and Wong, Melissa H.Y., additional
- Published
- 2021
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31. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 1—global current practice patterns for the management of Herpes Simplex Virus and Varicella Zoster Virus anterior uveitis
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Thng, Zheng Xian, Putera, Ikhwanuliman, Testi, Ilaria, Chan, Kevin, Westcott, Mark, Chee, Soon-Phaik, Dick, Andrew D., Kempen, John H., Bodaghi, Bahram, Thorne, Jennifer E., Barisani-Asenbauer, Talin, de Smet, Marc D., Smith, Justine R., McCluskey, Peter, La Distia Nora, Rina, Jabs, Douglas A., de Boer, Joke H., Sen, H. Nida, Goldstein, Debra A., Khairallah, Moncef, Davis, Janet L., Rosenbaum, James T., Jones, Nicholas P., Nguyen, Quan Dong, Pavesio, Carlos, Agrawal, Rupesh, and Gupta, Vishali
- Abstract
Aims: To present current expert practice patterns and to formulate a consensus for the management of HSV and VZV AU by uveitis specialists worldwide. Methods: A two-round online modified Delphi survey with masking of the study team was conducted. Responses were collected from 76 international uveitis experts from 21 countries. Current practices in the diagnosis and treatment of HSV and VZV AU were identified. A working group (The Infectious Uveitis Treatment Algorithm Network [TITAN]) developed data into consensus guidelines. Consensus is defined as a particular response towards a specific question meeting ≥75% of agreement or IQR ≤ 1 when a Likert scale is used. Results: Unilaterality, increased intraocular pressure (IOP), decreased corneal sensation and diffuse or sectoral iris atrophy are quite specific for HSV or VZV AU from consensus opinion. Sectoral iris atrophy is characteristic of HSV AU. Treatment initiation is highly variable, but most experts preferred valacyclovir owing to simpler dosing. Topical corticosteroids and beta-blockers should be used if necessary. Resolution of inflammation and normalisation of IOP are clinical endpoints. Conclusions: Consensus was reached on several aspects of diagnosis, choice of initial treatment, and treatment endpoints for HSV and VZV AU. Treatment duration and management of recurrences varied between experts.
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- 2023
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32. Iris Manifestations in Inadequately Treated Chronic Recurrent Vogt-Koyanagi-Harada Disease.
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Chee, Soon-Phaik and Win, May Zun Aung
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TRANSILLUMINATION , *IMMUNE reconstitution inflammatory syndrome , *IRIS (Eye) diseases , *ATROPHY , *SPHINCTERS - Abstract
To describe the iris changes in chronic recurrent Vogt-Koyanagi-Harada Disease (VKH) Retrospective case series. Clinical features of 3 VKH patients who developed bilateral depigmentation of the iris are described. Patients had delayed diagnosis and inadequately treated chronic recurrent VKH. Patient 1 presented with bilateral multiple contiguous small granulomatous iris stromal lesions, severe diffuse iris swelling more severe near the iris root, producing peripheral iris undulations. Diffuse iris atrophy and peripheral depigmentation subsequently developed. Patient 2 presented with peripheral iris depigmentation, atrophy of the ciliary zone iris stroma and sparing of the sphincter pupillae, giving a 'sunflower appearance.' Patient 3 had extensive iris depigmentation, atrophy, and transillumination defects involving the entire iris. Uncontrolled bilateral diffuse granulomatous stromal iris inflammation leads to subsequent depigmentation, transillumination defects and atrophy, beginning in the peripheral iris. Sphincter pupillae is initially spared but complete iris atrophy may develop. [ABSTRACT FROM AUTHOR]
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- 2022
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33. Contributors
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Abtahi, Maryam, Adams, Wendy, Afshari, Natalie A., Agarwal, Anita, Agranat, Joshua S., Ajlan, Radwan S., Akhlaq, Anam, Al-Aswad, Lama, AlBayyat, Ghada, Albini, Thomas A., Ghoul, Ahmed Al, Al-Mohtaseb, Zaina, Alvi, Nishat P., Apple, David J., Aquino, Maria Cecilia, Arnold, Anthony C., Arnoldi, Kyle, Arshinoff, Steve A., Asbell, Penny A., Ashe, Stephen A., Asroui, Lara, Atebara, Neal H., Awh, Katherine C., Aylward, G. William, Bacci, Tommaso, Bakri, Sophie J., Balcer, Laura J., Balducci, Nicole, Barboni, Piero, Baş, Zeynep, Basu, Soumyava, Baumal, Caroline R., Bessette, Angela P., Bhatt, Nirali, Bhullar, Paramjit K., Binotti, William, Birch, Eileen E., Biswas, Jyotirmay, Bjerregaard, Robert William, Bose, Swaraj, Bouchard, Charles S., Boulton, Michael E., Bouremel, Yann, Brandt, James D., Brocchini, Steve, Brodie, Scott E., Brodsky, Michael C., Brooks, Cassandra, Brown, Aaron Christopher, Budenz, Donald L., Cantor, Louis B., Capo, Hilda, Capone, Antonio, Jr., Carruthers, Alastair, Carruthers, Jean D., Carter, Keith D., Chahal, Harinderpal, Chan, Chi-Chao, Chan, Jane W., Chang, Melinda Y., Chang, Stanley, Charteris, David G., Chee, Soon-Phaik, Chen, Masako, Chen, Michael Yipeng, Chen, Sien, Chen, Xuejing, Tec Kuan Chew, Paul, Chong, Jillian K., Chow, Clement C., Clarke, Jonathan C.K., Codère, François, Conner, Ian P., Soledad Cortina, Maria, Couch, Steven M., Coupland, Stuart G., Cowan, Claude, Craven, E. Randy, Cukras, Catherine A., Dagi, Linda, Dalvin, Lauren A., Damgaard, Iben Bach, Fatehali Damji, Karim, Das, Dipankar, DeBusk, Adam, Carlo, Talisa E. de, Coulon, Sara Jacob, Demer, Joseph Louis, Desai, Shilpa J., Dhaliwal, Deepinder K., Dhawlikar, Nisha, Diamond, Gary R., Diaz, Jose Daniel, Diniz, Daniel, Djenderedjian, Levon, Do, Anna Thanh Tam, Do, Diana V., Dolman, Peter J., Donahue, Sean P., Drenser, Kimberly A., Duffy, Kevin R., Duker, Jacob S., Duker, Jay S., Dupps, William J., Jr., Durairaj, Vikram D., Dutton, Jonathan J., Eliott, Dean, Engelbert, Michael, Enzor, Rikki S., Epstein, Aliza, Evans, Joshua W., Evans, Monica, Faia, Lisa J., Fallano, Katherine A., Farjo, Ayad A., Fernandez, Karen B., Fisher, Yale L., Fortun, Jorge A., Friedman, Deborah I., Friedman, Neil J., Fynn-Thompson, Nicoletta, Gadaria-Rathod, Neha, Garg, Sumit (Sam), Gayre, Gregg, Gedde, Steven, Geevarghese, Alexi, Ghosh, Saurabh, William Gigantelli, James, Goerlitz-Jessen, Mark, Goldberg, Ivan, Goldberg, Jeffrey L., Goldstein, Debra A., Goldstein, Michael H., Gonzales, John A., Gore, Charlotte, Granet, David B., Greven, Craig M., Greven, Margaret A., Gross, Ronald L., Gündüz, Ahmet Kaan, Gupta, Preeya K., Haller, Julia A., Hamrah, Pedram, Hannush, Sadeer B., Hardin, Joshua S., Harris, Alon, Hassan, Muhammad, Heier, Jeffrey S., Herndon, Leon W., Ho, Allen C., Ho, Joanne W., Honasoge, Avinash, Hood, Christopher T., Houghton, Odette, Houser, Kourtney, Howes, Frank W., Hsu, Jason, Hurwitz, Jeffrey J., Irochima, Francisco, Isteitiya, Jihad, Iyer, Geetha, Izak, Andrea M., Jackson, Kevin, Jacob, Soosan, Jacoba, Cris Martin P., Jacobs, Deborah S., Jampel, Henry D., Jampol, Lee M., Jeng-Miller, Karen, Jing-Wei Chen, John, Johnson, Mark W., Johnson, T. Mark, Johnstone, Murray, Kaakour, Abdul-Hadi, Kaehr, Mark M., Kahook, Malik Y., Kaiser, Peter K., Kalafatis, Nicholas, Kalevar, Ananda, Kane, Steven, Kang, Kai, Kanner, Elliott M., Kapoor, Saloni, Alton Kapusta, Michael, Karanjia, Rustum, Kardon, Randy H., Karp, Carol L., Kashani, Amir H., Kass, Michael A., Kataguiri, Paula, Kaufman, Paul L., D. Keenan, Jeremy, Kelly, Elaine, Kenyon, Kenneth R., Khandelwal, Sumitra, Tee Khaw, Peng, Kim, Ivana K., Kim, Terry, Kinori, Michael, Kiss, Szilárd, Kitchens, John W., Klein, Kendra, Ko, Narae, Koch, Douglas D., Kodati, Shilpa, Koh, Victor, Kohnen, Thomas, Konstas, Angelos A., Koo, Ellen, Lane, Stephen S., Lavin, Patrick J.M., Lavinsky, Fabio, Lawton, Andrew W., Le, Nhon T., Lee, Bonny, Lee, Crystal, Lee, Gregory D., Lee, Paul P, Han Lee, Rachel, Ann Lim, Dawn Ka, Lin, Tony, Lind, John T., Liu, Dan, Liu, Yao, Liyanage, Sidath E., Longmuir, Reid A., Lundström, Mats, N. Maamari, Robi, Mahjoub, Heba, Maloney, Maya H., Mamalis, Christina, Manche, Edward E., Mandava, Naresh, Martheswaran, Tanisha, Masket, Samuel, Mattox, Cynthia, Kevin McClatchey, Scott, McLeod, Stephen D., McMillan, Brian D., McNab, Alan A., Mehra, Ankur, Mehta, Jodhbir S., Mejia-Vergara, Alvaro J., Mejico, Luis J., Mekhail, Joseph, N. Mercer, Ryan, Mian, Shahzad I., Mieler, William F., Miller, Kyle E., Mirza, Rukhsana G., Misra, Poonam, Mititelu, Mihai, Mohammed, Taariq, Moorthy, Ramana S., Morkin, Melina I., Moshfeghi, Andrew A., Moshirfar, Majid, Moss, Heather E., Moster, Mark L., Muhtaseb, Ruba, Muir, Kelly W., Neff, Ann G., Nerad, Jeffrey A., Ng, Caleb C., Nguyen, Annie, Nikpoor, Neda, Nosé, Ricardo, Okada, Annabelle A., Datoo O'Keefe, Ghazala A., Olson, Jeffrey L., Olver, Jane M., Örge, Faruk H., Packard, Richard, Packer, Mark, Panarelli, Joseph, Pandey, Suresh K., Parikh, Vishal S., Pasha, Hamza, Pasquale, Louis R., Patel, Palak, Patel, Sarju S., Patel, Shaila R., Patel, Vivek R., Pavesio, Carlos, Perez, Victor L., Phillips, Lauren T., Piltz-Seymour, Jody R., Piva, Alfio P., Presland, Andrew H., Price, Francis W., Price, Marianne O., Quiros, Peter A., Rachitskaya, Aleksandra, Rahmani, Safa, Ramulu, Pradeep Y., Randleman, J. Bradley, Rao, Narsing A., Rao, Naveen K., Rao, P. Kumar, Rao, Rajesh C., Rathinam, Sivakumar, Read, Russell W., Reed, Donovan, Vinícius Saito Regatieri, Caio, Regillo, Carl D., Reichel, Elias, Reighard, Chelsea L., Richard, Alyse, Ringeisen, Alexander, Ritch, Robert, Robbins, Shira L., M. Rocha, Karolinne, Rodger, Damien C., Roh, Miin, Rosado-Adames, Noel, Rowe, Lucas W., Rubenstein, Jonathan B., Rubin, Richard M., Rubsamen, Patrick E., Saadati, Hossein G., Sadun, Alfredo A., Saeedi, Osamah, Sajjad, Ahmar, Salchow, Daniel J., Salim, Sarwat, Salongcay, Recivall P., Sandhu, Simrenjeet, Santhiago, Marcony R., Satija, Celine E., M. Schallhorn, Julie, Schmitt, Melanie, Schor, Paulo, Schroeder, Richard, Schubert, Hermann D., Schuman, Joel S., Schwartz, Gary S., Sen, H. Nida, Shah, Gaurav K., Shah, Ravi, Shields, Carol L., Shields, Jerry A., Shildkrot, Yevgeniy (Eugene), Shingleton, Bradford J., Shtein, Roni M., Shu-Wen Chan, Nicole, Shultz, Ryan W., Sieck, Erin, Siesky, Brent, Sieving, Paul A., S. Silva, Paolo, Simmons, Kirsten, Skondra, Dimitra, Smiddy, William E., Somogyi, Marie, Soong, H. Kaz, Soukiasian, Sarkis H., Spoor, Thomas C., Srinivasan, Bhaskar, Srivastava, Sunil K., Starnes, Taylor W., Starr, Matthew R., Steel, David H., Steigleman, W. Allan, Stein, Joshua D., Stepien, Kimberly E., Stevens, Dylan V., Strominger, Mitchell B., Sugar, Alan, Sugar, Joel, Suh, Donny W., Sun, Michelle, Sun, Yang, Sychev, Yevgeniy V., Tai, Tania, Tan, James C., Tanenbaum, Myron, Tasman, William, Tassignon, Marie-José B., Testi, Ilaria, Thall, Edmond H., Thanos, Aristomenis, Theophanous, Christos N., Thornton, Sarah, Tingey, David P., Todorich, Bozho, Tompson, Stuart W., Toy, Brian, Tsai, James C., Tsai, Julie, Tucker, Nancy, Tuli, Sonal S., Valerio, Gabriel S., Vargason, Caroline W., Vasaiwala, Roshni A., Vitor Vasconcelos-Santos, Daniel, Vaughn, Gregory J., Venkateswaran, Nandini, Vinod, Kateki, Vislisel, Jesse M., Vrcek, Ivan, Walton, David S., Wang, Li, Wang, Michelle Y., Wang, Robert C., Waring IV, George O., Weikert, Mitchell P., Werner, Liliana, Wevill, Mark, Wiggs, Janey L., Williams, Andrew M., Williams, George A., Witmer, Matthew T., Wollstein, Gadi, Woodward, Maria A., Wride, Nicholas K., Wu, Albert Y., Yaghy, Antonio, Young, Joshua A., Zaguia, Fatma, Zein, Wadih M., and Zhu, Ivy
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- 2023
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34. 7.20 - Pars Planitis and Other Intermediate Uveitides
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Shu-Wen Chan, Nicole, Chee, Soon-Phaik, and Gonzales, John A.
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- 2023
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35. Contributors
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Abulafia, Adi, Agarwal, Ashvin, Agarwal, Kanika, Ahmad, Ashraf Freddie, Ahmed, Masih U., Al-Mohtaseb, Zaina, Assia, Ehud I., Bailey, Mark D., Barfell, Andrew D., Barrett, Graham, Basti, Surendra, Bhat, Amar Krishna, Brooks, Cassandra C., Böhm, Myriam, Carballo, Sarah E., Chang, David F., Chee, Soon-Phaik, Chen, Lauren E., Chhadva, Priyanka, Cohen, Kenneth L., Commiskey, Patrick W., Culp, Catherine J., Darvish, Mahshad, Davis, Elizabeth A., Dewey, Steven H., Dhaliwal, Deepinder K., Donaldson, Kendall E., Farid, Marjan, Figueiredo, Gabriel B., Findl, Oliver, Fine, I. Howard, Finn, Avni P., Fram, Nicole R., Garg, Sumit (Sam), Gupta, Preeya K., Hackett, Nicholas, Hemkeppler, Eva, Hill, Warren E., Hoffman, Richard S., Houser, Kourtney, Jacob, Soosan, Jalsingh, Ananya, Kalout, Patricia S.O., Kanesa-thasan, Aditya, Kedhar, Sanjay R., Khandelwal, Sumitra, Khurana, Rahul N., Kim, Terry, Kleinmann, Guy, Knezevic, Alexander, Koch, Douglas D., Kohnen, Thomas, Kwong, Stephen, Lee, Bryan S., Lee, Olivia L., Lim, Janet M., Lin, Ken Y., Lindstrom, Richard L., Mah, Francis S., Mamalis, Nick, Masket, Samuel, Mc, Guffey, Charles Daniel, Miller, Kevin M, Mittal, Aman, Narang, Priya, Noble, Carl W., Nuijts, Rudy M.M.A, Oetting, Thomas A., Ogawa, Gregory S.H., Osher, Robert H., Osher, James M., Palkovits, Stefan, Pantanelli, Seth Michel, Penatti, Raphael, Velasquez, Mauricio A. Perez, Pettey, Jeff, Pham, Don, Pineda, Roberto, Qu, Phillip, Radcliffe, Nathan M., Riemann, Christopher D., Rubenstein, Jonathan B., Rupnik, Zsófia, Seibel, Barry S., Shah, Manjool, Shah, Ravi, Sims, Annette Chang, Sivaraman, Kavitha R., Snyder, Michael E., Sood, Shana, Tan, Nicholas E., Teichman, Joshua C., Thompson, Vance, Ti, Seng-Ei, Venkatesh, Rengaraj, Venkateswaran, Nandini, Ventura, Bruna V., Ventura, Marcelo C., Viriya, Elizabeth T., Wade, Matthew, Wagner, Kirsten, Walter, Keith, Wang, Li, Wang, Yvonne, Waring, George O., IV, Warren, Alexis K., Warren, Keith A., Webers, Valentijn S.C., Weikert, Mitchell P., Werner, Liliana, Yeu-Lin, Elizabeth, and Zhou, Elaine J.
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- 2023
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36. 35 - Cataract Surgery in the Small Pupil
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Ti, Seng-Ei and Chee, Soon-Phaik
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- 2023
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37. Epidemiology of Viral Induced Anterior Uveitis.
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Radosavljevic, Aleksandra, Agarwal, Mamta, Chee, Soon Phaik, and Zierhut, Manfred
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Viral agents are the most common cause of infectious anterior uveitis worldwide. The purpose of this review is to analyze the frequency, gender and racial differences of viral anterior uveitis (VAU) in various populations. Systematized literature review of epidemiological reports of VAU cited in PubMed, EMBASE and the Cochrane Library database published until June 30th, 2020. A total of 12 clinical studies on epidemiology of definite VAU and 36 clinical studies of presumed VAU were identified. Members of Herpesviridae family represent the most common causes of VAU. Other less frequently reported causes, such as rubella and endemic viruses (HTLV-1, Chikungunya, Dengue, Ebola, Zika virus) were also analyzed. HSV, VZV are prevalent worldwide. CMV is more frequent in Asia, and rubella in the West. However, due to globalization and air travel, HTLV-1, Chikungunya, Dengue and Ebola may become important causes of VAU across the world. [ABSTRACT FROM AUTHOR]
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- 2022
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38. Management of the subluxated crystalline lens: A review.
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Chee, Soon‐Phaik, Ti, Seng‐Ei, and Chan, Nicole Shu‐Wen
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- *
CRYSTALLINE lens , *CATARACT surgery , *DISEASE progression , *ABERROMETRY , *INTRAOCULAR lenses , *RETRACTORS (Surgery) - Abstract
Cataract surgery for the subluxated crystalline lens is challenging. A thorough preoperative evaluation is important to determine the appropriate surgical approach for lens removal and the subsequent technique of intraocular lens placement. Important considerations include the extent and location of zonular weakness, and whether the zonular deficiency is caused by a static or progressive disease. The capsular bag should be preserved where possible. Creating a good‐sized and centred continuous curvilinear capsulorhexis is crucial to facilitate the use of capsular retractors and capsular tension devices, which provide capsular stability. Nucleus sculpting and rotation should be minimised to reduce zonular stress. Being cognisant of the possible intraoperative complications that may occur at each stage of the surgery and knowing how to reduce the risk of these complications occurring will enable surgeons to perform safe cataract surgery in these complex cases. [ABSTRACT FROM AUTHOR]
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- 2021
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39. Singapore Ocular Tuberculosis Immunity Study (SPOTIS): Role of T-lymphocyte Profiling in Patients with Presumed Ocular Tuberculosis.
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Hutchinson, Paul E., Kee, Ae Ra, Agrawal, Rupesh, Yawata, Nobuyo, Tumulak, Mayjane Jg, Connolly, John E., Chee, Soon-Phaik, and Siak, Jay
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CD4 antigen ,TUBERCULOSIS ,CD38 antigen ,T cells ,IMMUNITY ,TUBERCULOSIS diagnosis ,DRUG therapy for tuberculosis ,BACTERIAL proteins ,FLOW cytometry ,RESEARCH ,CASE-control method ,BACTERIAL antigens ,EVALUATION research ,COMPARATIVE studies ,ANTITUBERCULAR agents ,IMMUNOPHENOTYPING ,MYCOBACTERIUM tuberculosis ,RESEARCH funding ,CELLULAR immunity ,LONGITUDINAL method - Abstract
Objective: A prospective clinical study to assess the utility of CD4 + T cell lymphocyte profiling from peripheral blood in patients with ocular tuberculosis (TB).Methods: Thirty-six Asian patients with presumed diagnosis of ocular TB were recruited for T-lymphocyte profiling. MTB antigen specific CD4 assay was set up, and flow cytometric data were analyzed using FlowJo software.Results: There was no significant difference between treatment responders and non-responders for the proportion of CD4 + T cells specific for PPD or ESAT-6+ CFP-10, but treatment responders did have significantly higher frequency of CD38+ (p = .0357) and CD38+ HLA-DR+ (p = .0357) on the PPD-specific CD4 + T cells.Conclusion: This study is one of the first of its kind to look into MTB specific T cell activation marker profiling of peripheral blood in patients with ocular TB. Further studies need to be undertaken to assess the utility of CD4 + T cell phenotypes as a biomarker for ocular TB. [ABSTRACT FROM AUTHOR]
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- 2021
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40. Ocular Adverse Events After COVID-19 Vaccination.
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Ng, Xin Le, Betzler, Bjorn Kaijun, Testi, Ilaria, Ho, Su Ling, Tien, Melissa, Ngo, Wei Kiong, Zierhut, Manfred, Chee, Soon Phaik, Gupta, Vishali, Pavesio, Carlos E, de Smet, Marc D., and Agrawal, Rupesh
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COVID-19 vaccines ,FACIAL paralysis ,VACCINATION complications ,GRAVES' disease ,COVID-19 ,FACIAL nerve - Abstract
The COVID-19 pandemic has galvanized the development of new vaccines at an unprecedented pace. Since the widespread implementation of vaccination campaigns, reports of ocular adverse effects after COVID-19 vaccinations have emerged. This review summarizes ocular adverse effects possibly associated with COVID-19 vaccination, and discusses their clinical characteristics and management. Narrative Literature Review. Ocular adverse effects of COVID-19 vaccinations include facial nerve palsy, abducens nerve palsy, acute macular neuroretinopathy, central serous retinopathy, thrombosis, uveitis, multiple evanescent white dot syndrome, Vogt-Koyanagi-Harada disease reactivation, and new-onset Graves' Disease. Studies in current literature are primarily retrospective case series or isolated case reports – these are inherently weak in establishing association or causality. Nevertheless, the described presentations resemble the reported ocular manifestations of the COVID-19 disease itself. Hence, we hypothesize that the human body's immune response to COVID-19 vaccinations may be involved in the pathogenesis of the ocular adverse effects post-COVID-19 vaccination. Ophthalmologists and generalists should be aware of the possible, albeit rare, ocular adverse effects after COVID-19 vaccination. [ABSTRACT FROM AUTHOR]
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- 2021
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41. Endothelial keratoplasty with anterior chamber intraocular lens versus secondary posterior chamber intraocular lens
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Woo, Jyh Haur, Arundhati, Anshu, Chee, Soon-Phaik, Tong, Weihan, Li, Lim, Ti, Seng-Ei, Htoon, Hla M, Choo, Jessica Qian Hui, Tan, Donald, and Mehta, Jodhbir S
- Abstract
AimTo describe the long-term outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) with an anterior chamber intraocular lens (ACIOL) compared to secondary posterior chamber (PC) IOL.MethodsThis was a retrospective comparative cohort study. The clinical data of 82 eyes from 82 consecutive patients with pseudophakic (PBK) or aphakic bullous keratopathy (ABK) who either underwent DSAEK with retained or secondary ACIOL (n=23) or DSAEK with IOL exchange and/or secondary PCIOL (retropupillary iris-claw IOL, n=25; intrascleral-fixated IOL, n=29; or sulcus IOL, n=5) were analysed. The main outcome measures were graft survival and complications up to 5 years.ResultsThe graft survival in the secondary PCIOL group was superior than the ACIOL group over 5 years (year 1, 100.0% vs 100.0%; year 3, 94.7% vs 75.0%; year 5, 91.1% vs 60.6%, p=0.022). The presence of an ACIOL was a significant risk factor associated with graft failure (HR, 4.801; 95% CI, 1.406 to 16.396, p=0.012) compared to a secondary PCIOL. There was no significant difference in the rate of graft detachment and elevated intraocular pressure between the groups. There were five cases (9.3%) of IOL subluxation or dislocation in the retropupillary iris-claw and intrascleral-fixated IOL groups.ConclusionsEyes that underwent DSAEK with ACIOL in situ had poorer long-term graft survival compared with those with secondary PCIOL. Intraocular lens exchange was not associated with a higher complication rate. In ABK or PBK eyes with ACIOL, we recommend performing IOL exchange and/or secondary PCIOL implantation combined with endothelial keratoplasty.
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- 2022
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42. Presentation, Diagnostic Testing and Initial Treatment of Vitreoretinal Lymphoma
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Androudi, Sofia, Apivatthakakul, Atitaya, Arevalo, Fernando J., Berkenstock, Meghan K., Carreño, Ester, Chee, Soon-Phaik, Choovuthayakorn, Janejit, Cimino, Luca, Cornish, Elisa E., Farrall, Alexandra L., Gehl, Zsuzsanna, Gentile, Pietro, Gerges, Terese K., Gozzi, Fabrizio, Hernández-Pons, Antonio, Issa, Samar, Kim, Hyeong Min, Kim, Min, Knickelbein, Jared E., Kunavisarut, Paradee, Lee, Seung M., Lim, Lyndell L., Lin, Ming Lee, Llorenç, Victor, López-Sierra, Sara, Martínez-Costa, Lucía, McCluskey, Peter, Mochizuki, Manabu, O'Day, Roderick F., Pai, Amy S., Palestine, Alan G., Pathanapitoon, Kessara, Radford, Mark H.B., Silpa-Archa, Sukhum, Smith, Justine R., Terada, Yukiko, Waduthantri, Samanthila, Weaver, Travers R.E., Williams, Keryn L., Woo, Se Joon, and Younan, Christine
- Abstract
Vitreoretinal lymphoma is a malignancy with high mortality. Incidence is rare, and there is a lack of medical evidence to direct management. This work describes presentation, diagnostic testing, and first treatment approaches in a recently diagnosed and treated patient cohort.
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- 2023
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43. Iris‐sutured intraocular lenses and their long‐term outcomes.
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Lim, Jane S., Chiam, Nathalie P. Y., Wong, Melissa H. Y., and Chee, Soon‐Phaik
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- *
INTRAOCULAR lenses , *SUTURING , *SURGICAL complications , *MARFAN syndrome , *PARS plana , *VITRECTOMY , *OCULAR hypertension , *IRIDOCYCLITIS - Abstract
This article discusses the use of iris-sutured intraocular lenses (IOLs) and their long-term outcomes. The study found that iris-sutured IOLs had improved visual outcomes and a low risk of complications, but there were some associated risks such as elevated intraocular pressure and cystoid macular edema. The article also examines the surgical outcomes and safety of a procedure called combined trans pars plana vitrectomy with iris fixated posterior chamber intraocular lens for subluxated intraocular lens and cataracts. The study provides insights into the effectiveness and potential risks of this procedure over a one-year period. [Extracted from the article]
- Published
- 2024
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44. Systemic and Ocular Manifestations of Arboviral Infections: A Review.
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Khairallah, Moncef, Abroug, Nesrine, Smit, Derrick, Chee, Soon-Phaik, Nabi, Wijden, Yeh, Steven, Smith, Justine R., Ksiaa, Imen, and Cunningham, Emmett
- Abstract
PurposeMethodsResultsConclusionTo provide an overview of pre-selected emerging arboviruses (arthropod-borne viruses) that cause ocular inflammation in humans.A comprehensive review of the literature published between 1997 and 2023 was conducted in PubMed database. We describe current insights into epidemiology, systemic and ocular manifestations, diagnosis, treatment, and prognosis of arboviral diseases including West Nile fever, Dengue fever, Chikungunya, Rift Valley fever, Zika, and Yellow fever.Arboviruses refer to a group of ribonucleic acid viruses transmitted to humans by the bite of hematophagous arthropods, mainly mosquitoes. They mostly circulate in tropical and subtropical zones and pose important public health challenges worldwide because of rising incidence, expanding geographic range, and occurrence of prominent outbreaks as a result of climate change, travel, and globalization. The clinical signs associated with infection from these arboviruses are often inapparent, mild, or non-specific, but they may include serious, potentially disabling or life-threatening complications. A wide spectrum of ophthalmic manifestations has been described including conjunctival involvement, anterior uveitis, intermediate uveitis, various forms of posterior uveitis, maculopathy, optic neuropathy, and other neuro-ophthalmic manifestations. Diagnosis of arboviral diseases is confirmed with either real time polymerase chain reaction or serology. Management involves supportive care as there are currently no specific antiviral drug options. Corticosteroids are often used for the treatment of associated ocular inflammation. Most patients have a good visual prognosis, but there may be permanent visual impairment due to ocular structural complications in some. Community-based integrated mosquito management programs and personal protection measures against mosquito bites are the best ways to prevent human infection and disease.Emerging arboviral diseases should be considered in the differential diagnosis of ocular inflammatory conditions in patients living in or returning from endemic regions. Early clinical consideration followed by confirmatory testing can limit or prevent unnecessary treatments for non-arboviral causes of ocular inflammation. Prevention of these infections is crucial. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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45. Technique: Removal of Soemmering's ring using an intraocular lens cartridge Short title: Soemmering's ring removal with an intraocular lens cartridge.
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Chan NS and Chee SP
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- 2024
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46. Femtosecond laser-assisted cataract surgery for complex cataracts - A review.
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Chen DZ and Chee SP
- Subjects
- Humans, Visual Acuity, Laser Therapy methods, Cataract Extraction methods, Cataract complications
- Abstract
Since its inception in 2009, femtosecond laser-assisted cataract surgery (FLACS) has become an alternative to conventional phacoemulsification cataract surgery (CPCS). Clinical studies were unable to demonstrate superior visual outcomes, but revealed reduced endothelial cell loss. More recently, the cost-effectiveness of FLACS over CPCS in routine cataract surgeries has been challenged. However, the unique abilities of FLACS to customize anterior capsulotomies precisely, soften and fragment the nucleus without capsular bag stress, and create corneal incisions may have special utility in complex cataract and less-common scenarios. In this article, we review the unique role of FLACS in complex cataract surgeries and how it could play a role to improve the safety and predictability of nonroutine cataract surgery., (Copyright © 2024 Copyright: © 2024 Indian Journal of Ophthalmology.)
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- 2024
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47. Rupture of a posterior polar cataract after peribulbar block.
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Chen DZ, Hernstadt DJ, Lin HA, and Chee SP
- Published
- 2024
- Full Text
- View/download PDF
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