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22 results on '"Costa, Silvia F"'

1. Colonisation by multidrug-resistant organisms in health workers in primary care: narrow spectrum oral antimicrobials are a risk factor

Author

de Oliveira, Vítor Falcão, de Britto-Costa, Letícia Fernandes, de Aragão, Gabrielly Lacerda, Scaccia, Nazareno, Mamana, Ana Carolina, Côrtes, Marina Farrel, de Oliveira, Maura Salaroli, de Melo Tavares, Bruno, Manuli, Erika Regina, Leal, Fábio Eudes, de Oliveira Xavier, Gabriela Tonon, Grespan, Regina Maura Zetone, Sequeira, Cibele Cristine Remondes, Nunes, Fatima L. S., Dropa, Milena, Martone-Rocha, Solange, Razzolini, Maria Tereza Pepe, Sabino, Ester Cerdeira, Padoveze, Maria Clara, Holmes, Alison, Costa, Silvia F., and Levin, Anna S.

Published
2024
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4. Spatial and temporal fluctuations in COVID-19 fatality rates in Brazilian hospitals

Author

Brizzi, Andrea, Whittaker, Charles, Servo, Luciana M. S., Hawryluk, Iwona, Prete, Jr, Carlos A., de Souza, William M., Aguiar, Renato S., Araujo, Leonardo J. T., Bastos, Leonardo S., Blenkinsop, Alexandra, Buss, Lewis F., Candido, Darlan, Castro, Marcia C., Costa, Silvia F., Croda, Julio, de Souza Santos, Andreza Aruska, Dye, Christopher, Flaxman, Seth, Fonseca, Paula L. C., Geddes, Victor E. V., Gutierrez, Bernardo, Lemey, Philippe, Levin, Anna S., Mellan, Thomas, Bonfim, Diego M., Miscouridou, Xenia, Mishra, Swapnil, Monod, Mélodie, Moreira, Filipe R. R., Nelson, Bruce, Pereira, Rafael H. M., Ranzani, Otavio, Schnekenberg, Ricardo P., Semenova, Elizaveta, Sonabend, Raphael, Souza, Renan P., Xi, Xiaoyue, Sabino, Ester C., Faria, Nuno R., Bhatt, Samir, and Ratmann, Oliver

Published
2022
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6. Author Correction: Spatial and temporal fluctuations in COVID-19 fatality rates in Brazilian hospitals

Author

Brizzi, Andrea, Whittaker, Charles, Servo, Luciana M. S., Hawryluk, Iwona, Prete, Jr, Carlos A., de Souza, William M., Aguiar, Renato S., Araujo, Leonardo J. T., Bastos, Leonardo S., Blenkinsop, Alexandra, Buss, Lewis F., Candido, Darlan, Castro, Marcia C., Costa, Silvia F., Croda, Julio, de Souza Santos, Andreza Aruska, Dye, Christopher, Flaxman, Seth, Fonseca, Paula L. C., Geddes, Victor E. V., Gutierrez, Bernardo, Lemey, Philippe, Levin, Anna S., Mellan, Thomas, Bonfim, Diego M., Miscouridou, Xenia, Mishra, Swapnil, Monod, Mélodie, Moreira, Filipe R. R., Nelson, Bruce, Pereira, Rafael H. M., Ranzani, Otavio, Schnekenberg, Ricardo P., Semenova, Elizaveta, Sonabend, Raphael, Souza, Renan P., Xi, Xiaoyue, Sabino, Ester C., Faria, Nuno R., Bhatt, Samir, and Ratmann, Oliver

Published
2022
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7. Title Impact of Exogenous Lactobacillus plantarum on the Gut Microbiome of Hematopoietic Stem Cell Transplantation Patients Colonized by Multi-Drug Resistant Bacteria

Author

Moraes, Bruna D.G.C., primary, Martins, Roberta CR, additional, Fonseca, Joyce Vanessa da Silva, additional, Franco, Lucas AM, additional, Pereira, Gaspar CO, additional, Bartelli, Thaisi F, additional, Cortes, Marina F, additional, Santos, Carolina F, additional, Musqueira, Priscila T, additional, Otuyama, Leonardo J, additional, Pylro, Victor S., additional, Mariano, Livia, additional, Rocha, Vanderson, additional, Witkin, Steven S, additional, Sabino, Ester C, additional, Guimaraes, Thais, additional, and Costa, Silvia F, additional

Published
2023
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8. Launch of the São Paulo Wellcome Trust-funded multidisciplinary research program on optimising antimicrobial use in highly populated urban environments

Author

Levin, Anna S., primary, Costa, Silvia F., additional, Razzolini, Maria Tereza P., additional, Padoveze, Maria Clara, additional, Nunes, Fatima L.S., additional, Oliveira, Maura S., additional, Freire, Maristela P., additional, Tavares, Bruno M., additional, Assis, Denise B., additional, de Oliveira, Vitor F., additional, Leal, Fabio E., additional, Marcondes, Marta A., additional, Dropa, Milena, additional, Conde, Mônica T.R.P., additional, Oikawa, Marcio K., additional, Ferreira, João E., additional, Sabino, Ester, additional, Manuli, Erika R., additional, and Raymundo, Sueli F., additional

Published
2023
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9. Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated with Haemophilus influenzae Meningitis in a Newborn

Author

Ferreira, Noely Evangelista, primary, da Costa, Antonio C., additional, Kallas, Esper G., additional, Silveira, Cassia G. T., additional, de Oliveira, Ana Carolina S., additional, Honorato, Layla, additional, Paião, Heuder G. O., additional, Lima, Silvia H., additional, de M. Vasconcelos, Dewton, additional, Côrtes, Marina F., additional, Costa, Silvia F., additional, Mendoza, Tania R. T., additional, Gomes, Hélio R., additional, Witkin, Steven S., additional, and Mendes-Correa, Maria C., additional

Published
2023
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12. Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Shedding and Predictors of Viral Culture Positivity on Vaccinated Healthcare Workers With Mild Coronavirus Disease 2019

Author

Luna-Muschi, Alessandra, primary, Noguera, Saidy Vásconez, additional, Borges, Igor C, additional, De Paula, Anderson V, additional, Côrtes, Marina Farrel, additional, Larocca, Carolina, additional, Mari, Julia Ferreira, additional, Guimarães, Lara Silva Pereira, additional, Torres, Pablo Munoz, additional, Scaccia, Nazareno, additional, Villas-Boas, Lucy S, additional, da Silva, Almir Ribeiro, additional, Andrade, Pâmela S, additional, Teixeira, Juliana C, additional, Escadafal, Camille, additional, de Oliveira, Vitor Falcão, additional, Tozetto-Mendoza, Tania R, additional, Mendes-Correa, Maria Cássia, additional, Levin, Anna S, additional, Sabino, Ester C, additional, and Costa, Silvia F, additional

Published
2022
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14. Transmission of Carbapenem-Resistant Enterobacterales in an Overcrowded Emergency Department: Controlling the Spread to the Hospital.

Author

Salomão, Matias C, Freire, Maristela P, Lázari, Carolina S, Cury, Ana P, Rossi, Flávia, Segurado, Aluisio A C, Costa, Silvia F, Levin, Anna S, Boszczowski, Ícaro, and Force, Carbapenem Resistant Enterobacterales in Emergency Department (CRE-ED) Task

Subjects
HOST-bacteria relationships, LENGTH of stay in hospitals, HOSPITAL emergency services, CONFIDENCE intervals, CROWDS, RESEARCH methodology, CARBAPENEM-resistant bacteria, RISK assessment, INFECTIOUS disease transmission, RESEARCH funding, ODDS ratio, DISEASE risk factors
Abstract

Background Overcrowded emergency departments (EDs) may increase the risk of carbapenem-resistant Enterobacterales (CRE) transmission. Methods We conducted a quasi-experimental study divided into 2 phases (baseline and intervention) to investigate the impact of an intervention on the acquisition rate and identify risk factors for CRE colonization in an ED of a tertiary academic hospital in Brazil. In both phases, we did universal screening with rapid molecular test (bla KPC, bla NDM, bla OXA48, bla OXA23, and bla IMP) and culture. At baseline, both screening test results were not reported, and patients were put under contact precautions (CP) based on previous colonization or infection by multidrug-resistant organisms. During the intervention, all patients hospitalized in the ED were placed in empiric CP and the result of CRE screening was reported; if negative, patients were released from CP. Patients were rescreened if they stayed >7 days in the ED or were transferred to an intensive care unit. Results A total of 845 patients were included: 342 in baseline and 503 in intervention. Colonization at admission was 3.4% by culture and molecular test. Acquisition rates during ED stay dropped from 4.6% (11/241) to 1% (5/416) during intervention (P =.06). The aggregated antimicrobial use in the ED decreased from phase 1 to phase 2 (804 defined daily doses [DDD]/1000 patients to 394 DDD/1000 patients, respectively). Length of stay >2 days in the ED was a risk factor for CRE acquisition (adjusted odds ratio, 4.58 [95% confidence interval, 1.44–14.58]; P =.01). Conclusions Early empiric CP and rapid identification of CRE-colonized patients reduce cross-transmission in ED. Nevertheless, staying >2 days in ED compromised efforts. [ABSTRACT FROM AUTHOR]

Published
2023
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15. Clinical features of COVID-19 by SARS-CoV-2 Gamma variant: A prospective cohort study of vaccinated and unvaccinated healthcare workers

Author

Luna-Muschi, Alessandra, Borges, Igor C., de Faria, Elizabeth, Barboza, Antonio S., Maia, Fernando L., Leme, Mariana D., Guedes, Ana Rubia, Mendes-Correa, Maria Cassia, Kallas, Esper G., Segurado, Aluísio C., Duarte, Alberto J.S., Lazari, Carolina S., Andrade, Pamela S., Sales, Flávia C.S., Claro, Ingra M., Sabino, Ester C., Levin, Anna S., and Costa, Silvia F.

Published
2022
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16. Genetic risk factors and COVID-19 severity in Brazil: results from BRACOVID study

Author

Pereira, Alexandre C, primary, Bes, Taniela M, additional, Velho, Mariliza, additional, Marques, Emanuelle, additional, Jannes, Cintia E, additional, Valino, Karina R, additional, Dinardo, Carla L, additional, Costa, Silvia F, additional, Duarte, Alberto J S, additional, Santos, Alexandre R, additional, Mitne-Neto, Miguel, additional, Medina-Pestana, Jose, additional, and Krieger, Jose E, additional

Published
2022
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17. Healthcare-associated infections on the intensive care unit in 21 Brazilian hospitals during the early months of the coronavirus disease 2019 (COVID-19) pandemic: An ecological study

Author

Porto, Ana Paula M., primary, Borges, Igor C., additional, Buss, Lewis, additional, Machado, Anna, additional, Bassetti, Bil R., additional, Cocentino, Brunno, additional, Bicalho, Camila S., additional, Carrilho, Claudia M.D.M., additional, Rodrigues, Cristhieni, additional, Neto, Eudes A.S., additional, Girão, Evelyne S., additional, Piastrelli, Filipe, additional, Sapienza, Giovanna, additional, Varkulja, Glaucia, additional, Kolbe, Karin, additional, Passos, Luciana, additional, Esteves, Patricia, additional, Gitirana, Pollyana, additional, Feijó, Regia D.F., additional, Coutinho, Rosane L., additional, Guimarães, Thais, additional, Ferraz, Tiago L.L., additional, Levin, Anna S., additional, and Costa, Silvia F., additional

Published
2022
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18. Characterizing the SARS-CoV-2 Omicron variant shedding and duration of RT-PCR and rapid antigen test positivity on vaccinated individuals.

Author

Luna-Muschi, Alessandra, primary, Noguera, Saidy, additional, De Paula, Anderson, additional, Cortês, Marina, additional, Larocca, Carolina, additional, Mari, Julia, additional, Guimarâes, Lara, additional, Torres, Pablo, additional, Scaccia, Nazareno, additional, Villas-Boas, Lucy, additional, Silva, Almir Da, additional, Andrade, Pâmela, additional, Teixeira, Juliana, additional, De Oliveira, Victor, additional, Tozetto-Mendoza, Tania, additional, Mendes-Correa, Maria Cássia, additional, Levin, Anna S., additional, Sabino, Ester, additional, and Costa, Silvia F., additional

Published
2022
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20. Launch of the São Paulo Wellcome Trust-funded multidisciplinary research program on optimising antimicrobial use in highly populated urban environments

Author

Oliveira, Maura S., Freire, Maristela P., Tavares, Bruno M., Assis, Denise B., de Oliveira, Vitor F., Leal, Fabio E., Marcondes, Marta A., Dropa, Milena, Conde, Mônica T.R.P., Oikawa, Marcio K., Ferreira, João E., Sabino, Ester, Manuli, Erika R., Raymundo, Sueli F., Levin, Anna S., Costa, Silvia F., Razzolini, Maria Tereza P., Padoveze, Maria Clara, and Nunes, Fatima L.S.

Published
2023
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21. Healthcare-associated infections on the intensive care unit in 21 Brazilian hospitals during the early months of the coronavirus disease 2019 (COVID-19) pandemic: An ecological study

Author

Porto, Ana Paula M., Borges, Igor C., Buss, Lewis, Machado, Anna, Bassetti, Bil R., Cocentino, Brunno, Bicalho, Camila S., Carrilho, Claudia M.D.M., Rodrigues, Cristhieni, Neto, Eudes A.S., Girão, Evelyne S., Piastrelli, Filipe, Sapienza, Giovanna, Varkulja, Glaucia, Kolbe, Karin, Passos, Luciana, Esteves, Patricia, Gitirana, Pollyana, Feijó, Regia D.F., Coutinho, Rosane L., Guimarães, Thais, Ferraz, Tiago L.L., Levin, Anna S., and Costa, Silvia F.

Abstract

AbstractObjective:The coronavirus disease 2019 (COVID-19) pandemic has caused a global health crisis and may have affected healthcare-associated infection (HAI) prevention strategies. We evaluated the impact of the COVID-19 pandemic on HAI incidence in Brazilian intensive care units (ICUs).Methods:In this ecological study, we compared adult patients admitted to the ICU from April through June 2020 (pandemic period) with the same period in 2019 (prepandemic period) in 21 Brazilian hospitals. We used the Wilcoxon signed rank-sum test in a pairwise analysis to compare the following differences between the pandemic and the prepandemic periods: microbiologically confirmed central-line–associated bloodstream infection (CLABSI) and ventilator-associated pneumonia (VAP) incidence density (cases per 1,000 central line and ventilator days, respectively), the proportion of organisms that caused HAI, and antibiotic consumption (DDD).Results:We detected a significant increase in median CLABSI incidence during the pandemic: 1.60 (IQR, 0.44–4.20) vs 2.81 (IQR, 1.35–6.89) (P= .002). We did not detect a significant difference in VAP incidence between the 2 periods. In addition, we detected a significant increase in the proportion of CLABSI caused by Enterococcus faecalisand Candidaspp during the pandemic, although only the latter retained statistical significance after correction for multiple comparisons. We did not detect a significant change in ceftriaxone, piperacillin–tazobactam, meropenem, or vancomycin consumption between the studied periods.Conclusions:There was an increase in CLABSI incidence in Brazilian ICUs during the first months of COVID-19 pandemic. Additionally, we detected an increase in the proportion of CLABSI caused by E. faecalisand Candidaspp during this period. CLABSI prevention strategies must be reinforced in ICUs during the COVID-19 pandemic.

Published
2023
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22. Post-mortem diagnosis of human rabies in SARS-CoV-2 coinfected patient with minimally invasive autopsy in northeastern Brazil.

Author

Farias, Luis Arthur B. G., Sousa, Marcos M., de Araujo, Ruth Maria O., Maia, Kelma M., de Azevedo, Madalena Q., de Oliveira Caetano, Nancy C., Cavalcante, Karene F., Mello, Liana P., de Sousa, Larissa Leao F., de Andrade C. Gadelha, Sami, de Melo, Deborah N., Carneiro, Ana Karine B., Coelho, Tânia Mara S., Neto, Antônio Silva L., Abreu, Francisco Edson B., Kessiene de S. Cavalcante, Kellyn, Costa, Silvia F., de Goes Cavalcanti, Luciano P., and Perdigão Neto, Lauro V.

Abstract

Introduction: Human rabies (HR) is a lethal zoonotic disease caused by lyssaviruses with increase in the number of cases post-coronavirus disease 2019 (COVID-19) pandemic. Methodology: We report a case of human rabies in a patient from a rural area of Ceará, northeastern Brazil in 2023, who was bitten by a white-tufted-ear marmoset (Callithrix jacchus jacchus). The patient was co-infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and was diagnosed by minimally invasive autopsy (MIA). Results: MIA offers many advantages related to biosafety, and speed of sample acquisition; and markedly reduces disfigurement of the body compared with complete autopsy. It is a great alternative in COVID-19 patients. Conclusions: New methods such as MIA are a promising tool for diagnosis, and have the potential to improve family cooperation and support rabies surveillance. [ABSTRACT FROM AUTHOR]

Published
2024
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