169 results on '"D'Angelo, T"'
Search Results
2. Expedition 390/393 methods
- Author
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Coggon, R.M., primary, Teagle, D.A.H., additional, Sylvan, J.B., additional, Reece, J., additional, Estes, E.R., additional, Williams, T.J., additional, Christeson, G.L., additional, Aizawa, M., additional, Albers, E., additional, Amadori, C., additional, Belgrano, T.M., additional, Borrelli, C., additional, Bridges, J.D., additional, Carter, E.J., additional, D'Angelo, T., additional, Dinarès-Turell, J., additional, Doi, N., additional, Estep, J.D., additional, Evans, A., additional, Gilhooly III, W.P., additional, Grant, L.J.C., additional, Guérin, G.M., additional, Harris, M., additional, Hojnacki, V.M., additional, Hong, G., additional, Jin, X., additional, Jonnalagadda, M., additional, Kaplan, M.R., additional, Kempton, P.D., additional, Kuwano, D., additional, Labonte, J.M., additional, Lam, A.R., additional, Latas, M., additional, Lowery, C.M., additional, Lu, W., additional, McIntyre, A., additional, Moal-Darrigade, P., additional, Pekar, S.F., additional, Robustelli Test, C., additional, Routledge, C.M., additional, Ryan, J.G., additional, Santiago Ramos, D., additional, Shchepetkina, A., additional, Slagle, A.L., additional, Takada, M., additional, Tamborrino, L., additional, Villa, A., additional, Wang, Y., additional, Wee, S.Y., additional, Widlansky, S.J., additional, Yang, K., additional, Kurz, W., additional, Prakasam, M., additional, Tian, L., additional, Yu, T., additional, and Zhang, G., additional
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- 2024
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3. Site U1560
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Teagle, D.A.H., primary, Reece, J., additional, Williams, T.J., additional, Coggon, R.M., additional, Sylvan, J.B., additional, Estes, E.R., additional, Christeson, G.L., additional, Albers, E., additional, Amadori, C., additional, Belgrano, T.M., additional, D'Angelo, T., additional, Doi, N., additional, Evans, A., additional, Guérin, G.M., additional, Harris, M., additional, Hojnacki, V.M., additional, Hong, G., additional, Jin, X., additional, Jonnalagadda, M., additional, Kuwano, D., additional, Labonte, J.M., additional, Lam, A.R., additional, Latas, M., additional, Lu, W., additional, Moal-Darrigade, P., additional, Pekar, S.F., additional, Robustelli Test, C., additional, Ryan, J.G., additional, Santiago Ramos, D., additional, Shchepetkina, A., additional, Villa, A., additional, Wee, S.Y., additional, Widlansky, S.J., additional, Aizawa, M., additional, Borrelli, C., additional, Bridges, J.D., additional, Carter, E.J., additional, Dinarès-Turell, J., additional, Estep, J.D., additional, Gilhooly III, W.P., additional, Grant, L.J.C., additional, Kaplan, M.R., additional, Kempton, P.D., additional, Lowery, C.M., additional, McIntyre, A., additional, Routledge, C.M., additional, Slagle, A.L., additional, Takada, M., additional, Tamborrino, L., additional, Wang, Y., additional, Yang, K., additional, Kurz, W., additional, Prakasam, M., additional, Tian, L., additional, Yu, T., additional, and Zhang, G., additional
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- 2024
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4. Site U1556
- Author
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Coggon, R.M., primary, Sylvan, J.B., additional, Estes, E.R., additional, Teagle, D.A.H., additional, Reece, J., additional, Williams, T.J., additional, Christeson, G.L., additional, Aizawa, M., additional, Borrelli, C., additional, Bridges, J.D., additional, Carter, E.J., additional, Dinarès-Turell, J., additional, Estep, J.D., additional, Gilhooly III, W.P., additional, Grant, L.J.C., additional, Kaplan, M.R., additional, Kempton, P.D., additional, Lowery, C.M., additional, McIntyre, A., additional, Routledge, C.M., additional, Slagle, A.L., additional, Takada, M., additional, Tamborrino, L., additional, Wang, Y., additional, Yang, K., additional, Albers, E., additional, Amadori, C., additional, Belgrano, T.M., additional, D'Angelo, T., additional, Doi, N., additional, Evans, A., additional, Guérin, G.M., additional, Harris, M., additional, Hojnacki, V.M., additional, Hong, G., additional, Jin, X., additional, Jonnalagadda, M., additional, Kuwano, D., additional, Labonte, J.M., additional, Lam, A.R., additional, Latas, M., additional, Lu, W., additional, Moal-Darrigade, P., additional, Pekar, S.F., additional, Robustelli Test, C., additional, Ryan, J.G., additional, Santiago Ramos, D., additional, Shchepetkina, A., additional, Villa, A., additional, Wee, S.Y., additional, Widlansky, S.J., additional, Kurz, W., additional, Prakasam, M., additional, Tian, L., additional, Yu, T., additional, and Zhang, G., additional
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- 2024
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5. Expedition 390/393 summary
- Author
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Coggon, R.M., primary, Teagle, D.A.H., additional, Sylvan, J.B., additional, Reece, J., additional, Estes, E.R., additional, Williams, T.J., additional, Christeson, G.L., additional, Aizawa, M., additional, Albers, E., additional, Amadori, C., additional, Belgrano, T.M., additional, Borrelli, C., additional, Bridges, J.D., additional, Carter, E.J., additional, D'Angelo, T., additional, Dinarès-Turell, J., additional, Doi, N., additional, Estep, J.D., additional, Evans, A., additional, Gilhooly III, W.P., additional, Grant, L.J.C., additional, Guérin, G.M., additional, Harris, M., additional, Hojnacki, V.M., additional, Hong, G., additional, Jin, X., additional, Jonnalagadda, M., additional, Kaplan, M.R., additional, Kempton, P.D., additional, Kuwano, D., additional, Labonte, J.M., additional, Lam, A.R., additional, Latas, M., additional, Lowery, C.M., additional, Lu, W., additional, McIntyre, A., additional, Moal-Darrigade, P., additional, Pekar, S.F., additional, Robustelli Test, C., additional, Routledge, C.M., additional, Ryan, J.G., additional, Santiago Ramos, D., additional, Shchepetkina, A., additional, Slagle, A.L., additional, Takada, M., additional, Tamborrino, L., additional, Villa, A., additional, Wang, Y., additional, Wee, S.Y., additional, Widlansky, S.J., additional, Yang, K., additional, Kurz, W., additional, Prakasam, M., additional, Tian, L., additional, Yu, T., additional, and Zhang, G., additional
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- 2024
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6. Low-impact line construction retains and speeds recovery of trees on seismic lines in forested peatlands
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Filicetti, Angelo T., Tigner, Jesse, Nielsen, Scott E., Wolfenden, Katherine, Taylor, Murdoch, and Bentham, Paula
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Peat-bogs -- Environmental aspects ,Trees -- Environmental aspects ,Oil and gas exploration -- Environmental aspects -- Methods ,Earth sciences - Abstract
Seismic lines are linear features created by the oil and gas industry for energy exploration. Though individually narrow, collectively seismic lines are a pervasive management challenge, resulting in changes to biogeochemical cycles, plant and animal abundance and behaviour, predator-prey relationships, and forest successional trajectories. These impacts arise from historical construction methods that used bulldozers to remove vegetation and substrate leaving lines as persistent openings in a state of arrested succession. In the mid-1990s, 'low-impact seismic' (LIS) line construction began, using mulchers to remove vegetation aboveground to minimize impacts and hasten reforestation. Here, we evaluated the effectiveness of LIS in retention, recruitment, and growth of seedlings in forested peatlands in northeast British Columbia. Retained and recruited trees on LIS lines were found at 69% and 64% of sites, had mean densities of 3400 and 6000 stems/ha, and mean heights of 42 and 11 cm, respectively. These LIS lines appeared to recover along expected trajectories toward tree cover, thereby mitigating challenges typical of older seismic exploration. Our results suggest it is feasible to further fast-forward line recovery by ensuring mulcher drums are kept as high as possible to increase the number and height of trees through the mulching process. Key words: seismic line, linear disturbance, boreal forest, forest gap, disturbance recovery, 1. Introduction Seismic lines (hereafter lines) are narrow linear features ( In part, the management challenges of lines in forested landscapes stem from their persistence as open (unforested) disturbances that [...]
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- 2023
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7. How young radiologists use contrast media and manage adverse reactions: an international survey
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Albano, D, Mallardi, C, Afat, S, Agnollitto, P, Caruso, D, Cannella, R, Carriero, S, Chupetlovska, K, Clauser, P, D'Angelo, T, De Santis, D, Dioguardi Burgio, M, Dumic-Cule, I, Fanni, S, Fusco, S, Gatti, M, Gitto, S, Jankovic, S, Karagechev, T, Klontzas, M, Koltsakis, E, Leithner, D, Matisic, V, Muscogiuri, G, Penkova, R, Polici, M, Serpi, F, Sofia, C, Snoj, Z, Akinci D'Antonoli, T, Vernuccio, F, Vieira, J, Vieira, A, Wielema, M, Zerunian, M, Messina, C, Albano D., Mallardi C., Afat S., Agnollitto P. M., Caruso D., Cannella R., Carriero S., Chupetlovska K., Clauser P., D'Angelo T., De Santis D., Dioguardi Burgio M., Dumic-Cule I., Fanni S. C., Fusco S., Gatti M., Gitto S., Jankovic S., Karagechev T., Klontzas M. E., Koltsakis E., Leithner D., Matisic V., Muscogiuri G., Penkova R., Polici M., Serpi F., Sofia C., Snoj Z., Akinci D'Antonoli T., Vernuccio F., Vieira J., Vieira A. C., Wielema M., Zerunian M., Messina C., Albano, D, Mallardi, C, Afat, S, Agnollitto, P, Caruso, D, Cannella, R, Carriero, S, Chupetlovska, K, Clauser, P, D'Angelo, T, De Santis, D, Dioguardi Burgio, M, Dumic-Cule, I, Fanni, S, Fusco, S, Gatti, M, Gitto, S, Jankovic, S, Karagechev, T, Klontzas, M, Koltsakis, E, Leithner, D, Matisic, V, Muscogiuri, G, Penkova, R, Polici, M, Serpi, F, Sofia, C, Snoj, Z, Akinci D'Antonoli, T, Vernuccio, F, Vieira, J, Vieira, A, Wielema, M, Zerunian, M, Messina, C, Albano D., Mallardi C., Afat S., Agnollitto P. M., Caruso D., Cannella R., Carriero S., Chupetlovska K., Clauser P., D'Angelo T., De Santis D., Dioguardi Burgio M., Dumic-Cule I., Fanni S. C., Fusco S., Gatti M., Gitto S., Jankovic S., Karagechev T., Klontzas M. E., Koltsakis E., Leithner D., Matisic V., Muscogiuri G., Penkova R., Polici M., Serpi F., Sofia C., Snoj Z., Akinci D'Antonoli T., Vernuccio F., Vieira J., Vieira A. C., Wielema M., Zerunian M., and Messina C.
- Abstract
Objectives: To collect real-world data about the knowledge and self-perception of young radiologists concerning the use of contrast media (CM) and the management of adverse drug reactions (ADR). Methods: A survey (29 questions) was distributed to residents and board-certified radiologists younger than 40 years to investigate the current international situation in young radiology community regarding CM and ADRs. Descriptive statistics analysis was performed. Results: Out of 454 respondents from 48 countries (mean age: 31.7 ± 4 years, range 25–39), 271 (59.7%) were radiology residents and 183 (40.3%) were board-certified radiologists. The majority (349, 76.5%) felt they were adequately informed regarding the use of CM. However, only 141 (31.1%) received specific training on the use of CM and 82 (18.1%) about management ADR during their residency. Although 266 (58.6%) knew safety protocols for handling ADR, 69.6% (316) lacked confidence in their ability to manage CM-induced ADRs and 95.8% (435) expressed a desire to enhance their understanding of CM use and handling of CM-induced ADRs. Nearly 300 respondents (297; 65.4%) were aware of the benefits of contrast-enhanced ultrasound, but 249 (54.8%) of participants did not perform it. The preferred CM injection strategy in CT parenchymal examination and CT angiography examination was based on patient’s lean body weight in 318 (70.0%) and 160 (35.2%), a predeterminate fixed amount in 79 (17.4%) and 116 (25.6%), iodine delivery rate in 26 (5.7%) and 122 (26.9%), and scan time in 31 (6.8%) and 56 (12.3%), respectively. Conclusion: Training in CM use and management ADR should be implemented in the training of radiology residents. Critical relevance statement: We highlight the need for improvement in the education of young radiologists regarding contrast media; more attention from residency programs and scientific societies should be focused on training about contrast media use and the management of adverse drug reactions. Key
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- 2024
8. DEVELOPMENT OF ARDUINO-BASED ELECTRONIC COMPONENT TESTING DEVICE.
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Entienza, Rexcel, Sarmiento, Jeffrey, and Mercado, Mark Angelo T.
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ELECTRONIC equipment ,ELECTRONIC circuits ,INTEGRATED circuits ,EDUCATIONAL innovations ,USER experience - Abstract
As advancements in electronics continued, the limitations of traditional component testers became increasingly evident. Most available testers were designed to evaluate a single component type, resulting in a circuit testing process that was often cumbersome and time-consuming. This inefficiency posed challenges to both learning and innovation in educational and professional environments. To address the growing demand for more efficient and versatile testing tools, the development of a multi-component tester became crucial. The proposed project aimed to create an integrated electronic components tester capable of evaluating a wide range of components, including integrated circuits (ICs), resistors, transistors, and capacitors. This all-in-one device was designed to streamline the testing process, improving the user experience in electronics laboratories and supporting professionals in the fields of electronics repair and development. [ABSTRACT FROM AUTHOR]
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- 2024
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9. The Negative Effects of Illegal Cockfighting at the Barangay Gulod Novaliches Quezon City: Vol. 3, No. 1A
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Tampilic, Joe Arvin I., Bonilla, Bryan Angelo T., Calumag, Jhonpol D., Cansancio, Joshua F., Creer, Jemar P., Tampilic, Joe Arvin I., Bonilla, Bryan Angelo T., Calumag, Jhonpol D., Cansancio, Joshua F., and Creer, Jemar P.
- Abstract
This research aims to identify the negative effects of illegal cockfighting at Barangay Gulod, Novaliches, Quezon City. Cockfights or “Sabong” is letting two roosters fight in an arena and betting on which wins. Regulation of live cockfighting in cockpit arenas is regulated by the Local Government Unit concerned. On the other hand, online sabong or e-sabong is regulated by the Philippine Amusement and Gaming Corporation (PAGCOR) and is currently allowed to legally operate e-sabong or online sabong at Lucky 8 Star Quest, owned by Atong Ang and Belvedere Corporation, owned by Bong Pineda. The researchers used the interview questions to gather and record information needed in the study. This study shows that illegal cockfighting addiction causes an uncontrollable urge to gamble more. Gambling addiction can be difficult to conceal, even if you gamble at home when no one is around. Your addiction may begin to show itself in other areas of your life.
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- 2024
10. Single Board Computer-Based Cataract And Glaucoma Classification And Detection System Using Deep Convolutional Neural Network.
- Author
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Guintu, Amiel Josiah R., Narvaez, Julius G., Mendoza, Julian Harvey B., de Mesa, Kierven R., and Mercado, Mark Angelo T.
- Abstract
This study introduces an innovative strategy for the identification and categorization of cataract and glaucoma utilizing a Single Board Computer (SBC)-based platform coupled with Deep Convolutional Neural Networks (CNNs). By harnessing the power of SBCs, our system facilitates rapid computational analysis of ocular images, streamlining the diagnostic process for timely intervention. Our methodology leverages CNNs to autonomously discern distinctive features from retinal images, ensuring precise and reliable classification of cataract and glaucoma cases. Through the fusion of advanced image processing techniques and cutting-edge deep learning methodologies, our framework achieves remarkable levels of accuracy. Experimental findings substantiate the effectiveness of our proposed approach in accurately identifying cataract and glaucoma, underscoring its potential for early detection and intervention in ocular diseases. [ABSTRACT FROM AUTHOR]
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- 2024
11. Artificial Intelligence in Cardiovascular CT and MR Imaging
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Lanzafame, L, Bucolo, G, Muscogiuri, G, Sironi, S, Gaeta, M, Ascenti, G, Booz, C, Vogl, T, Blandino, A, Mazziotti, S, D'Angelo, T, Lanzafame L. R. M., Bucolo G. M., Muscogiuri G., Sironi S., Gaeta M., Ascenti G., Booz C., Vogl T. J., Blandino A., Mazziotti S., D'Angelo T., Lanzafame, L, Bucolo, G, Muscogiuri, G, Sironi, S, Gaeta, M, Ascenti, G, Booz, C, Vogl, T, Blandino, A, Mazziotti, S, D'Angelo, T, Lanzafame L. R. M., Bucolo G. M., Muscogiuri G., Sironi S., Gaeta M., Ascenti G., Booz C., Vogl T. J., Blandino A., Mazziotti S., and D'Angelo T.
- Abstract
The technological development of Artificial Intelligence (AI) has grown rapidly in recent years. The applications of AI to cardiovascular imaging are various and could improve the radiologists’ workflow, speeding up acquisition and post-processing time, increasing image quality and diagnostic accuracy. Several studies have already proved AI applications in Coronary Computed Tomography Angiography and Cardiac Magnetic Resonance, including automatic evaluation of calcium score, quantification of coronary stenosis and plaque analysis, or the automatic quantification of heart volumes and myocardial tissue characterization. The aim of this review is to summarize the latest advances in the field of AI applied to cardiovascular CT and MR imaging.
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- 2023
12. Performance Characterization of a Developed Battery Electric Tricycle
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Tayo, Leo Allen S., primary, Tria, Lew Andrew R., additional, Giron, Janine D., additional, Sermeno, Belle S., additional, Santiago, Alessandro T., additional, Yago, John Angelo N., additional, Domingo, Mark Arnel B., additional, Cabaddu, Marc Angelo T., additional, and Purisima, Lemuel B., additional
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- 2023
- Full Text
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13. LigMANet: Towards Designing a Lightweight Crowd Counting Model
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Cua, Lander Peter E., primary, Gaba, Jacob Bryan B., additional, Lee, Hylene Jules G., additional, Racoma, Ian Angelo T., additional, and Antioquia, Arren Matthew C., additional
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- 2023
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14. Spectroscopic and photothermal characterization of graphene quantum dots for antimicrobial applications.
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Catanio, Angelo T. S., Bergmann, Eduardo V., Kimura, Newller M., Petrucci, Thiago, Freitas, Camila F., Herculano, Leandro S., Malacarne, Luis C., and Astrath, Nelson G. C.
- Subjects
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QUANTUM dots , *GRAPHENE , *REACTIVE oxygen species , *SALINE solutions , *LIGHT sources , *DRUG resistance in microorganisms - Abstract
Antimicrobial resistance is a challenging health problem that demands alternative treatments. Nanoplatforms with antimicrobial properties, associated with photodynamic and photothermal therapies, are potential candidates for this task due to characteristics such as non-invasive, antibiotic-free, dual selectivity, and low adverse effects in therapeutic procedures. Graphene quantum dots are a possible substitute for other nanoparticles, especially by presenting low toxicity and low cost. However, graphene quantum dot properties are highly dependent on the synthesis methods, which makes it difficult to compare and improve methods using different studies. In this work, we apply spectroscopic and photothermal methods to investigate a commercially available green fluorescent graphene quantum dot (GQD) as a potential antimicrobial agent and to determine its theranostics properties. The results showed that the photoactivation of the GQD in phosphate-buffered saline solution by light sources with wavelengths shorter than the emission band can generate singlet oxygen and a heat yield of 50 % under excitation at 532 nm, showing the potential of this GQD as a photodynamic and photothermal agent. [ABSTRACT FROM AUTHOR]
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- 2022
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15. Multimodality imaging in acute myocarditis
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Muscogiuri, G, Guaricci, A, Cau, R, Saba, L, Senatieri, A, Chierchia, G, Pontone, G, Volpato, V, Palmisano, A, Esposito, A, Basile, P, Marra, P, D'Angelo, T, Booz, C, Rabbat, M, Sironi, S, Muscogiuri G., Guaricci A. I., Cau R., Saba L., Senatieri A., Chierchia G., Pontone G., Volpato V., Palmisano A., Esposito A., Basile P., Marra P., D'angelo T., Booz C., Rabbat M., Sironi S., Muscogiuri, G, Guaricci, A, Cau, R, Saba, L, Senatieri, A, Chierchia, G, Pontone, G, Volpato, V, Palmisano, A, Esposito, A, Basile, P, Marra, P, D'Angelo, T, Booz, C, Rabbat, M, Sironi, S, Muscogiuri G., Guaricci A. I., Cau R., Saba L., Senatieri A., Chierchia G., Pontone G., Volpato V., Palmisano A., Esposito A., Basile P., Marra P., D'angelo T., Booz C., Rabbat M., and Sironi S.
- Abstract
The diagnosis of acute myocarditis often involves several noninvasive techniques that can provide information regarding volumes, ejection fraction, and tissue characterization. In particular, echocardiography is extremely helpful for the evaluation of biventricular volumes, strain and ejection fraction. Cardiac magnetic resonance, beyond biventricular volumes, strain, and ejection fraction allows to characterize myocardial tissue providing information regarding edema, hyperemia, and fibrosis. Contemporary cardiac computed tomography angiography (CCTA) can not only be extremely important for the assessment of coronary arteries, pulmonary arteries and aorta but also tissue characterization using CCTA can be an additional tool that can explain chest pain with a diagnosis of myocarditis.
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- 2022
16. Multimodality Imaging Evaluation of Coronary IgG4-Related Disease: A “Tumor-Like” Cardiac Lesion
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Lanzafame, L, Carerj, M, Rizzo, G, Minutoli, F, Bucolo, G, Irrera, N, Muscogiuri, G, Sironi, S, Blandino, A, D'Angelo, T, Lanzafame L. R. M., Carerj M. L., Rizzo G., Minutoli F., Bucolo G. M., Irrera N., Muscogiuri G., Sironi S., Blandino A., D'Angelo T., Lanzafame, L, Carerj, M, Rizzo, G, Minutoli, F, Bucolo, G, Irrera, N, Muscogiuri, G, Sironi, S, Blandino, A, D'Angelo, T, Lanzafame L. R. M., Carerj M. L., Rizzo G., Minutoli F., Bucolo G. M., Irrera N., Muscogiuri G., Sironi S., Blandino A., and D'Angelo T.
- Abstract
Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibro-inflammatory disorder. Coronary IgG4-RD has been scarcely reported and may present as “tumor-like” lesions. These pseudo-masses may be underdiagnosed mainly due to a vague clinical picture that can vary from complete lack of symptoms to acute coronary syndrome or sudden cardiac death. Early recognition of coronary IgG4-RD is essential to monitor disease activity and prevent life-threatening complications. We report a comprehensive non-invasive imaging evaluation of a patient affected by coronary IgG4-RD, which was diagnosed as an incidental finding during routine pre-laparoscopic cholecystectomy checkup. Non-invasive imaging revealed the presence of a peri-coronary soft-tissue mass that was stable at 12 months follow-up.
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- 2022
17. Artificial intelligence, machine learning and deep learning in musculoskeletal imaging: Current applications
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D'Angelo, T, Caudo, D, Blandino, A, Albrecht, M, Vogl, T, Gruenewald, L, Gaeta, M, Yel, I, Koch, V, Martin, S, Lenga, L, Muscogiuri, G, Sironi, S, Mazziotti, S, Booz, C, D'Angelo T., Caudo D., Blandino A., Albrecht M. H., Vogl T. J., Gruenewald L. D., Gaeta M., Yel I., Koch V., Martin S. S., Lenga L., Muscogiuri G., Sironi S., Mazziotti S., Booz C., D'Angelo, T, Caudo, D, Blandino, A, Albrecht, M, Vogl, T, Gruenewald, L, Gaeta, M, Yel, I, Koch, V, Martin, S, Lenga, L, Muscogiuri, G, Sironi, S, Mazziotti, S, Booz, C, D'Angelo T., Caudo D., Blandino A., Albrecht M. H., Vogl T. J., Gruenewald L. D., Gaeta M., Yel I., Koch V., Martin S. S., Lenga L., Muscogiuri G., Sironi S., Mazziotti S., and Booz C.
- Abstract
Artificial intelligence is rapidly expanding in all technological fields. The medical field, and especially diagnostic imaging, has been showing the highest developmental potential. Artificial intelligence aims at human intelligence simulation through the management of complex problems. This review describes the technical background of artificial intelligence, machine learning, and deep learning. The first section illustrates the general potential of artificial intelligence applications in the context of request management, data acquisition, image reconstruction, archiving, and communication systems. In the second section, the prospective of dedicated tools for segmentation, lesion detection, automatic diagnosis, and classification of musculoskeletal disorders is discussed.
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- 2022
18. Quick Response Code System Integrated ID for Construction Firms: Approach to the New Normal
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Melvin S. Cayanan, Jimwell G. Flores, Adrian G. Laxamana, Joshua G. Mallari, Nathaniel D. San Juan, Michael Angelo T. Torres, Mariane P. Nunag, Carl Jason A. Coronel, Mike Diether B. Galvez, Melvin S. Cayanan, Jimwell G. Flores, Adrian G. Laxamana, Joshua G. Mallari, Nathaniel D. San Juan, Michael Angelo T. Torres, Mariane P. Nunag, Carl Jason A. Coronel, and Mike Diether B. Galvez
- Abstract
The manual attendance system is consuming the working hours of a worker, causing a delay in work production. It is commonly known that using a digital attendance system (Quick Response Code System) is faster and safer than using a manual approach. This study shows how much time can be saved by a QR code system for digital attendance in a construction site that aims to maximize the working hours. In this context, a Quick Response Code is a sequence of black and white squares that can be read by machines. It's usually used to save URLs and other information that your mobile camera can read. To be able to get the results, we tested the system at the construction site in San Fernando, Pampanga. We requested permission from the higher-ups, and they granted it. We tested the workers and we got good results. It is more efficient if their id's have QR code and not the manual or the biometrics that they normally use, and by using the QR code, there will be less contact, especially in this pandemic, because they have their own id.
- Published
- 2023
19. Dynamic monitoring of the Temple of Neptune in Paestum (Italy) - Preliminary results.
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Petti, L, Lupo, C, and D'Angelo, T
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- 2023
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20. The 2019 northeast Brazil oil spill: scenarios
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PAULO NOBRE, ANGELO T. LEMOS, EMANUEL GIAROLLA, ROSIO CAMAYO, LAERCIO NAMIKAWA, MILTON KAMPEL, NATÁLIA RUDORFF, DIEGO X. BEZERRA, JOÃO LORENZZETTI, JORGE GOMES, MANOEL B. DA SILVA JR, CARLA P.M. LAGE, RAFAEL L. PAES, CARLOS BEISL, MÁRCIO M. LOBÃO, PEDRO A. BIGNELLI, NAJLA DE MOURA, WOUGRAN S. GALVÃO, and PAULO S. POLITO
- Subjects
Multidisciplinary ,Petroleum ,scenarios ,2019 oil spill ,ocean modeling ,Petroleum Pollution ,Northeast Brazil ,satellite imagery ,Brazil ,Water Pollutants, Chemical ,Environmental Monitoring - Abstract
During the last quarter of 2019, the beaches, mangroves, and estuaries of Northeast Brazil received an unprecedented volume of crude oil from the sea, which became the worst environmental disaster ever to reach the Brazilian coast. The oil, having reached the shores completely unnoticed, left both society and government agents completely clueless on (i) where the oil was coming from; (ii) how much oil was still in the ocean to reach the shorelines; and (iii) which beaches were going to be affected next! By exploring remote sensing data and ocean numerical modeling, along with oil dispersion chemistry on sea water, this study investigates the possible origin and path of the spill and whether it could have been detected from space. The oil dispersion modeling simulations performed for this investigation revealed a possible region and timing of the oil spill, also indicating the likelihood of it being advected toward the shoreline under the ocean surface.
- Published
- 2022
21. Multimodality imaging to assess severity and outcome in asymptomatic patients with aortic stenosis: a medium-long term follow-up study
- Author
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Zito, C, primary, Manganaro, R, additional, De Sarro, R, additional, Licordari, R, additional, Bursi, F, additional, Mantovani, F, additional, Benfari, G, additional, Malagoli, A, additional, Bertolacelli, Y, additional, D'Angelo, T, additional, Antonini-Canterin, F, additional, Carerj, S, additional, and Barbieri, A, additional
- Published
- 2022
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22. Decoupling of respiration rates and abundance in marine prokaryoplankton
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Munson-McGee, J.H., Lindsay, M.R., Sintes, E., Brown, J.M., D’Angelo, T., Brown, J., Lubelczyk, L.C., Tomko, P., Emerson, D., Orcutt, B.N., Poulton, N.J., Herndl, G.J., Stepanauskas, R., Munson-McGee, J.H., Lindsay, M.R., Sintes, E., Brown, J.M., D’Angelo, T., Brown, J., Lubelczyk, L.C., Tomko, P., Emerson, D., Orcutt, B.N., Poulton, N.J., Herndl, G.J., and Stepanauskas, R.
- Abstract
The ocean–atmosphere exchange of CO2 largely depends on the balance between marine microbial photosynthesis and respiration. Despite vast taxonomic and metabolic diversity among marine planktonic bacteria and archaea (prokaryoplankton), their respiration usually is measured in bulk and treated as a ‘black box’ in global biogeochemical models; this limits the mechanistic understanding of the global carbon cycle. Here, using a technology for integrated phenotype analyses and genomic sequencing of individual microbial cells, we show that cell-specific respiration rates differ by more than 1,000× among prokaryoplankton genera. The majority of respiration was found to be performed by minority members of prokaryoplankton (including the Roseobacter cluster), whereas cells of the most prevalent lineages (including Pelagibacter and SAR86) had extremely low respiration rates. The decoupling of respiration rates from abundance among lineages, elevated counts of proteorhodopsin transcripts in Pelagibacter and SAR86 cells and elevated respiration of SAR86 at night indicate that proteorhodopsin-based phototrophy probably constitutes an important source of energy to prokaryoplankton and may increase growth efficiency. These findings suggest that the dependence of prokaryoplankton on respiration and remineralization of phytoplankton-derived organic carbon into CO2 for its energy demands and growth may be lower than commonly assumed and variable among lineages.
- Published
- 2022
23. Prospective Study Investigating the Efficacy and Safety of a Scalp Cooling Device for the Prevention of Alopecia in Women Undergoing (Neo)Adjuvant Chemotherapy for Breast Cancer
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Carbognin, L., Accetta, C., Di Giorgio, D., Fuso, P., Muratore, M., Tiberi, G., Pavese, F., D'Angelo, T., Fabi, A., Giannarelli, D., Di Leone, A., Magno, S., Garganese, G., Sanchez, A. M., Terribile, D. A., Franceschini, G., Masetti, R., Scambia, G., Paris, I., Fuso P., Muratore M., Giannarelli D., Di Leone A., Magno S., Garganese G. (ORCID:0000-0002-4209-5285), Terribile D. A. (ORCID:0000-0002-3511-0010), Franceschini G. (ORCID:0000-0002-2950-3395), Masetti R. (ORCID:0000-0002-7520-9111), Scambia G. (ORCID:0000-0003-2758-1063), Paris I., Carbognin, L., Accetta, C., Di Giorgio, D., Fuso, P., Muratore, M., Tiberi, G., Pavese, F., D'Angelo, T., Fabi, A., Giannarelli, D., Di Leone, A., Magno, S., Garganese, G., Sanchez, A. M., Terribile, D. A., Franceschini, G., Masetti, R., Scambia, G., Paris, I., Fuso P., Muratore M., Giannarelli D., Di Leone A., Magno S., Garganese G. (ORCID:0000-0002-4209-5285), Terribile D. A. (ORCID:0000-0002-3511-0010), Franceschini G. (ORCID:0000-0002-2950-3395), Masetti R. (ORCID:0000-0002-7520-9111), Scambia G. (ORCID:0000-0003-2758-1063), and Paris I.
- Abstract
The prevention of chemotherapy-induced alopecia still represents an urgent need for every day clinical practice. In this regard, this prospective single-center study included breast cancer (BC) patients who underwent a scalp cooling device (Dignicap®) during (neo)adjuvant chemotherapy with the aim to evaluate the efficacy and safety of this device in preventing alopecia. One hundred and seventy-eight patients (median age 43 years) were enrolled. The chemotherapy regimen included anthracycline and taxane-based chemotherapy (68.1%), docetaxel and cyclophosphamide (25.8%), anthracycline and taxane-based plus carboplatin (3.9%), and paclitaxel alone (2.2%). In 25.3% of cases, a dose dense schedule was used. Overall, the success rate was 68.0%: 100% in paclitaxel alone, 87.0% in docetaxel-cyclophosphamide, 59.5% in anthracycline and taxane, and 71.4% in the sequential regimen plus carboplatin group (anthracycline and taxane-based chemotherapy versus taxane-based chemotherapy, p ≤ 001. No difference in terms of hair preservation between dose-dense or standard schedule was found (p = 0.557). Early discontinuation of the scalp cooling was observed in 50 patients (28.1%). Although 138 patients (77.5%) experienced adverse events, 70.2% of patients were satisfied with this device. In conclusion, this large prospective study confirmed the helpful effect of the scalp cooling system in preventing alopecia in BC patients also undergoing sequential anthracyclines and taxane-based chemotherapy.
- Published
- 2022
24. E-HEALTH ARMBAND REMINDER WITH GPS TRACKER FOR STREET SWEEPER OF CENRO CALAMBA CITY, LAGUNA.
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Nueva, John Paul R., Mayrina, Tricia, Enriquez, Wilmer T., Gueta, Harrold M., and Mercado, Mark Angelo T.
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SYSTEMS development ,REQUIREMENTS engineering - Abstract
This study presents the development of an E-Health Armband Reminder with a GPS tracker designed specifically for Street sweepers of CENRO Calamba City, Laguna. The objective of this project is to enhance the safety and efficiency of street sweeping operations by providing real-time monitoring and reminders to the sweepers. The E-health Armband Reminder incorporates a GPS tracker that allows supervisors to track the location of the sweepers in real-time. This feature enables efficient deployment of resources and facilitates prompt assistance in case of emergencies or accidents. Additionally, the armband serves as a reminder tool, providing alerts and not ifications for hydration, Weather, and safety protocols. The system's development involved extensive research, analysis of user requirements, and collaboration with the street sweepers and CENRO Calamba City. The armband's design and functionality were optimized to suit the specific needs and constraints of the street sweeping operation. Preliminary testing of the E-Health Armband Reminder demonstrated promising results, showing improved task management as the Attendance monitoring and increased safety awareness among the street sweepers. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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25. AI-WEAR: SMART TEXT READER FOR BLIND/VISUALLY IMPAIRED STUDENTS USING RASPBERRY PI WITH AUDIO-VISUAL CALL AND GOOGLE ASSISTANCE.
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Llorca, Allen A., Gueta, Harrold M., Villarica, Mia V., and Mercado, Mark Angelo T.
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VISUALLY impaired students ,RASPBERRY Pi ,OPTICAL character recognition ,STREAMING video & television ,INTERNET access ,IMAGE processing - Abstract
The goal of this research is to create a prototype referred to as AI-WEAR: Smart Text Reader for Blind or Visually Impaired Students, which utilizes Raspberry Pi equipped with Audio-Visual Call and Google Assistance. The prototype incorporates various functionalities including text-to-speech capability for reading, Google assistance for online support, and video streaming through Jitsi Meet, enabling students to interact with their teachers. The device offers two modes of control: voice commands and user-friendly buttons with Braille letters engraved on them. OCR (Optical Character Recognition) and Text-to-Speech are integrated into the system. Synthesis techniques on the Raspberry Pi platform. By utilizing OCR, the device scans and extracts text, which is then converted into audio output through a headset. Additionally, the device employs GSM/GPRS technology to access the internet via cellular data when Wi-Fi connectivity is unavailable. The researcher employed the Long-Short Term Memory and Image processing algorithms in this project, and extensive testing and maintenance have been conducted, resulting in favourable evaluation outcomes. The prototype has successfully met the desires of the ISO/IEC 25010 standard. Al though some adjustments may be necessary, this proposed device has significant potential to provide visually impaired individuals with innovative learning opportunities, especially in distance education settings. Furthermore, a cost-comparative analysis for future mass production of this assistive prototype tool for blind and visually impaired has been conducted. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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26. CSS QUEST: GAMIFYING COMPUTER SYSTEM SERVICING MODULE USING GAMIFIED PROGRESS TRACKING AND INTERACTIVE STORYTELLING ALGORITHM FOR GRADE 12 STUDENTS IN CALAMBA CITY.
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Mercado, Mark Angelo T., Llorca, Allen A., Villarica, Mia V., and Gueta, Harrold M.
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COMPUTER systems ,DIGITAL storytelling ,GRADING of students ,LEARNING ,ALGORITHMS ,CRITICAL thinking - Abstract
CSS Quest is an innovative educational initiative aimed at enhancing the learning experience of Grade 12 students in Calamba City, Laguna, specifically focusing on computer system servicing. This project utilizes gamified progress tracking and an interactive storytelling algorithm to engage students in an immersive learning environment. By merging elements of gaming, progress tracking, and interactive storytelling, CSS Quest seeks to foster a more effective and enjoyable learning process. The gamified progress tracking system empowers students to monitor their own progress, achievements, and goals throughout the module. Students will earn points, badges, and rewards for completing various tasks, solving challenges, and mastering key concepts related to computer system servicing. This gamification approach not only encourages healthy competition among students but also instils a sense of accomplishment, motivating them to actively participate in the learning process. To further enhance engagement, CSS Quest incorporates an interactive storytelling algorithm that presents the module content in a narrative-driven format. Through captivating storylines and characters, students will embark on a virtual journey, simulating real-life computer system servicing scenarios. They will be faced with challenges and problem-solving opportunities that mirror practical situations, thereby honing their critical thinking and decision-making skills. The CSS Quest initiative aims to address the traditional limitations of classroom-based learning by providing an interactive and dynamic platform that resonates with the digital-native generation. By leveraging gamification and interactive storytelling, it creates an engaging and immersive learning experience for Grade 12 students in Calamba City, Laguna. This approach promotes active participation, knowledge retention, and skill development, ultimately preparing students for real-world challenges in the field of computer system servicing. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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27. MANGROVE SIMULATION: ATTENUATION OF STORM SURGES IN PROTECTING COASTAL AREA AND GEOSPATIAL SIMULATION MODEL OF MANGROVE FOREST IN PALSABANGON MANGROVE SWAMP FOREST RESERVE PAGBILAO, QUEZON.
- Author
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Gueta, Harrold M., Llorca, Allen A., Villarica, Mia V., and Mercado, Mark Angelo T.
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MANGROVE plants ,MANGROVE swamps ,MANGROVE forests ,STORM surges ,FOREST reserves ,GEOGRAPHIC information systems ,SYSTEM administrators - Abstract
The objective of this research is to designed and developed a system known as Mangrove Simulation: Attenuation of Storm Surges in Protecting Coastal Area and Geospatial Simulation Model of Mangrove Forest in Palsabangon Mangrove Swamp Forest Reserve Pagbilao, Quezon. The system incorporates various functionalities including web-based application and geographical information system for administrator and staff of Palsabangon Mangrove Swamp Forest Reserve. To utilize the Agent-Based model that simulate and predict the growth and spatial distribution of various mangrove species with regards to the environment. To evaluate of the accuracy of the algorithm in mangrove simulation with geographic information system mapping aims to improve they understanding of the ecological dynamics and spatial patterns of mangroves, and provide useful information for the management and conservation of mangrove ecosystems. The system underwent a comprehensive testing process to assess its functionality, suitability, reliability, performance efficiency, operability, security, compatibility, and maintainability. The results revealed that the system achieved an overall mean score of 4.09, indicating a "Very Satisfactory" rating. This signifies that both experts and clients were very satisfied with the system's characteristics. Moreover, it passed on the standard rating level of ISO/IEC 25010. This remark indicates that the system performed effectively and achieved its goals. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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28. Effects of wildfire and soil compaction on recovery of narrow linear disturbances in upland mesic boreal forests
- Author
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Filicetti, Angelo T., primary and Nielsen, Scott E., additional
- Published
- 2022
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- View/download PDF
29. LIVED EXPERIENCES OF SCIENCE TEACHERS OF PANGASINAN II IN THE NEW NORMAL EDUCATION: A PHENOMENOLOGICAL STUDY
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Allan S. Guillermo and Angelo T. Manzano
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ComputingMilieux_COMPUTERSANDEDUCATION ,Lived Experiences New Normal Science Teachers Learning Delivery Modality - Abstract
The Covid-19 pandemic brought unprecedented challenges in the sector of Philippine education. The Department of Education Basic Education Learning Continuity Plan (BE-LCP) aims to ensure the continuity of learning thus, Pangasinan Division II implemented the Printed Modular Distance Learning (MDL) for the school year 2020-2021. The primary objective of this study is to understand the lived experiences of Science Teachers of Pangasinan Division II in the new normal setting of education. Using phenomenology, this study explored the challenges in adapting the new learning modality, the implementation of Most Essential Learning Competencies (MELCs), the production, distribution, and retrieval of self-learning modules (SLMs), the implementation of the interim guidelines in the grading system in the new normal education and the priority developmental plans and needs of Science teachers. From the data gathered through interview and analysis of the documents among twenty (20) Science teachers, it revealed that emerging themes capped into the acronym SURVIVORS which unfolds the Science teachers characteristics and experiences in the new face of education. The results showed that Science teachers are service-oriented, and the stakeholders showed unwavering support of stakeholders in the new learning modality. However, majority of the teachers exclaimed that distribution and retrieval of modules is the primary problem that arise from the different schools. Science teachers cope with these challenges through community partnerships and extending linkages that help them facilitate the distribution and retrieval of modules. In addition to that, Science teachers also acknowledged that printed modular learning should be shifted to blended learning as a modality in delivering education in the succeeding years. Integrating ICT through E-learning or online asynchronous learning could supplement the learners competencies alongside with the printed modules. Also, Science teachers have common priority development needs in terms of functional and core competencies. Lastly, it is notable that Science teachers should always be flexible and adaptive in their roles of as facilitators of education.  
- Published
- 2022
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30. Spreading and accumulation of river-borne sediments in the coastal ocean after the environmental disaster at the Doce River in Brazil
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Angelo T. Lemos, Alexander Osadchiev, Piero L. F. Mazzini, Guilherme N. Mill, Sabrina A. R. Fonseca, and Renato D. Ghisolfi
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Aquatic Science ,Oceanography ,Water Science and Technology - Published
- 2022
31. Geographical heterogeneity of clinical and serological phenotypes of systemic sclerosis observed at tertiary referral centres. The experience of the Italian SIR-SPRING registry and review of the world literature
- Author
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Clodoveo Ferri a, Rossella De Angelis b, Dilia Giuggioli a, Gianluigi Bajocchi c, Lorenzo Dagna d, Giovanni Zanframundo e, Rosario Foti f, Fabio Cacciapaglia g, Giovanna Cuomo, Alarico Ariani i, Edoardo Rosato j, Serena Guiducci k, Francesco Girelli l, Valeria Riccieri m, Elisabetta Zanatta n, Silvia Bosello o, Ilaria Cavazzana p, Francesca Ingegnoli q, Maria De Santisr, Giuseppe Murdaca s, Giuseppina Abignano t, Nicoletta Romeo u, Alessandra Della Rossa v, Maurizio Caminiti w, Annamaria Iuliano x, Giovanni Ciano y, Lorenzo Beretta z, Gianluca Bagnato aa, Ennio Lubrano ab, Ilenia De Andres ac, Alessandro Giollo ad, Marta Saracco ae, Cecilia Agnes af, Federica Lumetti a, Amelia Spinella a, Luca Magnani c, Corrado Campochiaro d, Giacomo De Luca d, Veronica Codullo e, Elisa Visalli f, Francesco Masini h, Antonietta Gigante j, Silvia Bellando-Randone k, Greta Pellegrino m, Erika Pigatto ag, Maria Grazia Lazzaroni p, Franco Franceschini p, Elena Generali r, Gianna Mennillo t, Simone Barsotti v, Giuseppa Pagano Mariano w, Francesca Calabrese w, Federica Furini ah, Licia Vultaggio ah, Simone Parisi ai, Clara Lisa Peroni ai, Davide Rozza aj, Anna Zanetti aj, Greta Carrara aj, Giampiero Landolfi aj, Carlo Alberto Scir`e aj, Gerolamo Bianchi al, Enrico Fusaro ai, Gian Domenico Sebastiani x, Marcello Govoni ah, Salvatore D’Angelo t, Franco Cozzi ag, Andrea Doria n, Florenzo Iannone g, Carlo Salvarani c, Marco Matucci-Cerinic d, k, On behalf of SPRING-SIR (Systemic Sclerosis PRogression INvestiGation group of the Italian Society of Rheumatology), A, Clodoveo Ferri, B, Rossella De Angeli, A, Dilia Giuggioli, C, Gianluigi Bajocchi, D, Lorenzo Dagna, E, Giovanni Zanframundo, F, Rosario Foti, G, Fabio Cacciapaglia, Cuomo, Giovanna, I, Alarico Ariani, J, Edoardo Rosato, K, Serena Guiducci, L, Francesco Girelli, M, Valeria Riccieri, N, Elisabetta Zanatta, O, Silvia Bosello, P, Ilaria Cavazzana, Q, Francesca Ingegnoli, De Santisr, Maria, S, Giuseppe Murdaca, T, Giuseppina Abignano, U, Nicoletta Romeo, V, Alessandra Della Rossa, W, Maurizio Caminiti, X, Annamaria Iuliano, Y, Giovanni Ciano, Z, Lorenzo Beretta, Bagnato aa, Gianluca, Lubrano ab, Ennio, De Andres ac, Ilenia, Giollo ad, Alessandro, Saracco ae, Marta, Agnes af, Cecilia, A, Federica Lumetti, A, Amelia Spinella, C, Luca Magnani, D, Corrado Campochiaro, D, Giacomo De Luca, E, Veronica Codullo, F, Elisa Visalli, H, Francesco Masini, J, Antonietta Gigante, K, Silvia Bellando-Randone, M, Greta Pellegrino, Pigatto ag, Erika, P, Maria Grazia Lazzaroni, P, Franco Franceschini, R, Elena Generali, T, Gianna Mennillo, V, Simone Barsotti, W, Giuseppa Pagano Mariano, W, Francesca Calabrese, Furini ah, Federica, Vultaggio ah, Licia, Parisi ai, Simone, Lisa Peroni ai, Clara, Rozza aj, Davide, Zanetti aj, Anna, Carrara aj, Greta, Landolfi aj, Giampiero, Alberto Scir`e aj, Carlo, Ak, Bianchi al, Gerolamo, Fusaro ai, Enrico, X, Gian Domenico Sebastiani, Govoni ah, Marcello, T, Salvatore D’Angelo, Cozzi ag, Franco, N, Andrea Doria, G, Florenzo Iannone, C, Carlo Salvarani, D, Marco Matucci-Cerinic, K, and behalf of SPRING-SIR (Systemic Sclerosis PRogression INvestiGation group of the Italian Society of Rheumatology), On
- Subjects
Systemic sclerosis Scleroderma Geographical areas Macro-areas Environmental Referral - Published
- 2022
32. Insight into the Adsorption Structure of TIPS-Pentacene on Noble Metal Surfaces
- Author
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Breeman, Brian, primary, Tiglias, Angelo T., additional, Mancuso, Joseph, additional, Zurek, Eva, additional, Miller, Daniel P., additional, and Velarde, Luis, additional
- Published
- 2022
- Full Text
- View/download PDF
33. Spreading and accumulation of river-borne sediments in the coastal ocean after the environmental disaster at the Doce River in Brazil
- Author
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Lemos, Angelo T., primary, Osadchiev, Alexander, additional, Mazzini, Piero L. F., additional, Mill, Guilherme N., additional, Fonseca, Sabrina A. R., additional, and Ghisolfi, Renato D., additional
- Published
- 2022
- Full Text
- View/download PDF
34. The 2019 northeast Brazil oil spill: scenarios
- Author
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NOBRE, PAULO, primary, LEMOS, ANGELO T., additional, GIAROLLA, EMANUEL, additional, CAMAYO, ROSIO, additional, NAMIKAWA, LAERCIO, additional, KAMPEL, MILTON, additional, RUDORFF, NATÁLIA, additional, BEZERRA, DIEGO X., additional, LORENZZETTI, JOÃO, additional, GOMES, JORGE, additional, SILVA JR, MANOEL B. DA, additional, LAGE, CARLA P.M., additional, PAES, RAFAEL L., additional, BEISL, CARLOS, additional, LOBÃO, MÁRCIO M., additional, BIGNELLI, PEDRO A., additional, MOURA, NAJLA DE, additional, GALVÃO, WOUGRAN S., additional, and POLITO, PAULO S., additional
- Published
- 2022
- Full Text
- View/download PDF
35. Spectroscopic and photothermal characterization of graphene quantum dots for antimicrobial applications
- Author
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Angelo T. S. Catanio, Eduardo V. Bergmann, Newller M. Kimura, Thiago Petrucci, Camila F. Freitas, Leandro S. Herculano, Luis C. Malacarne, and Nelson G. C. Astrath
- Subjects
General Physics and Astronomy - Abstract
Antimicrobial resistance is a challenging health problem that demands alternative treatments. Nanoplatforms with antimicrobial properties, associated with photodynamic and photothermal therapies, are potential candidates for this task due to characteristics such as non-invasive, antibiotic-free, dual selectivity, and low adverse effects in therapeutic procedures. Graphene quantum dots are a possible substitute for other nanoparticles, especially by presenting low toxicity and low cost. However, graphene quantum dot properties are highly dependent on the synthesis methods, which makes it difficult to compare and improve methods using different studies. In this work, we apply spectroscopic and photothermal methods to investigate a commercially available green fluorescent graphene quantum dot (GQD) as a potential antimicrobial agent and to determine its theranostics properties. The results showed that the photoactivation of the GQD in phosphate-buffered saline solution by light sources with wavelengths shorter than the emission band can generate singlet oxygen and a heat yield of [Formula: see text] under excitation at 532 nm, showing the potential of this GQD as a photodynamic and photothermal agent.
- Published
- 2022
36. Effects of wildfire and soil compaction on recovery of narrow linear disturbances in upland mesic boreal forests
- Author
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Angelo T. Filicetti and Scott E. Nielsen
- Subjects
Forestry ,Management, Monitoring, Policy and Law ,Nature and Landscape Conservation - Published
- 2022
37. Fire and tree recovery on seismic lines
- Author
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Filicetti, Angelo T.
- Subjects
- Seismic line, linear disturbance, forest regeneration, tree regeneration, forest restoration, forest gap, wildfire, woodland caribou, jack pine, aspen, black spruce
- Abstract
Abstract: The world’s forests are highly fragmented by linear disturbances, many of which have failed to recover decades after abandonment. Lack of recovery is common, most notably in xeric and hydric forests. Possible mechanisms for this lack of recovery are: life history traits of local species, lack of recent wildfires that encourage tree regeneration, soil compaction, and simplification of microtopography that leads to a loss of microsites for tree establishment. The persistence of these disturbances affects biodiversity, but of particular concern in Canada’s boreal forest are the detrimental effects on threatened woodland caribou. Although natural regeneration of trees on linear disturbances occurs in some places (passive restoration), it is not considered to be an effective recovery strategy for restoring disturbed habitat of woodland caribou. This has led to active restoration efforts of silviculture and tree planting where costs can exceed $12,500 (CAD) per km of seismic line. Current restoration models do not, however, consider wildfires that although destroy planted trees, can also initiate early seral conditions that favor natural regeneration. Here, I examine patterns in passive restoration, with and without recent wildfires, possible mechanisms for places that lack recovery, and the effectiveness of active restoration treatments of seismic lines in northern Alberta, Canada. Life history traits, such as fire serotinous-cones, suckering, and shade tolerance, best explain patterns of recovery for many sites. Overall, regeneration density and tree heights on most lines met suggested restoration guidelines (1000 stems/ha and 5-m height) within a 20-year period. Seismic lines in uplands sites may experience moderate levels of compaction, but it did not appear to affect regeneration rates. Except for fens, wildfires promoted increases in tree regeneration density and height on seismic lines, but this requires waiting for places to burn. Because fens burn less frequently and typically experience lower fire severity, as well as losing microtopography during line clearing, tree recovery here is slower than elsewhere, but may still be suitable considering tree density and heights here are naturally lower. Active restoration treatments of seismic lines, and in particular in peatlands with mounding, promoted natural tree regeneration and tree growth over the short-term (< 5-yrs) thus overcoming site limitations (most notably the loss of microtopography), but longer-term studies are needed to assess their long-term success and cost-benefit of passive restoration strategies that depend on natural regeneration and in many cases wildfires.
- Published
- 2021
38. Cardiovascular magnetic resonance of cardiac tumors and masses
- Author
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Alessandro Andreis, Riccardo Faletti, Andrea Carisio, Gianluca Pontone, Tommaso D’Angelo, Serena Dell'Aversana, Davide Tore, Giuseppe Muscogiuri, Marco Gatti, Fatemeh Darvizeh, Gatti, M, D'Angelo, T, Muscogiuri, G, Dell'Aversana, S, Andreis, A, Carisio, A, Darvizeh, F, Tore, D, Pontone, G, and Faletti, R
- Subjects
medicine.medical_specialty ,Cine magnetic resonance imaging ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Minireviews ,Early gadolinium enhancement ,Heart neoplasm ,Multiparametric magnetic resonance imaging ,Multimodal imaging ,Medicine ,Radiology ,Late-gadolinium enhancement ,Cardiology and Cardiovascular Medicine ,business ,Cardiac Tumors - Abstract
Cardiac masses diagnosis and treatment are a true challenge, although they are infrequently encountered in clinical practice. They encompass a broad set of lesions that include neoplastic (primary and secondary), non-neoplastic masses and pseudomasses. The clinical presentation of cardiac tumors is highly variable and depends on several factors such as size, location, relation with other structures and mobility. The presumptive diagnosis is made based on a preliminary non-invasive diagnostic work-up due to technical difficulties and risks associated with biopsy, which is still the diagnostic gold standard. The findings should always be interpreted in the clinical context to avoid misdiagnosis, particularly in specific conditions (e.g., infective endocarditis or thrombi). The modern multi-modality imaging techniques has a key role not only for the initial assessment and differential diagnosis but also for management and surveillance of the cardiac masses. Cardiovascular magnetic resonance (CMR) allows an optimal non-invasive localization of the lesion, providing multiplanar information on its relation to surrounding structures. Moreover, with the additional feature of tissue characterization, CMR can be highly effective to distinguish pseudomasses from masses, as well as benign from malignant lesions, with further differential diagnosis of the latter. Although histopathological assessment is important to make a definitive diagnosis, CMR plays a key role in the diagnosis of suspected cardiac masses with a great impact on patient management. This literature review aims to provide a comprehensive overview of cardiac masses, from clinical and imaging protocol to pathological findings.
- Published
- 2021
39. IL-13 and IL-33 Serum Levels Are Increased in Systemic Sclerosis Patients With Interstitial Lung Disease
- Author
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Antonio Giovanni Versace, Alessandra Bitto, Carmelo Ioppolo, Caterina Oriana Aragona, Daniela La Rosa, William Neal Roberts, Tommaso D'Angelo, Antonella Cinquegrani, Santa Cirmi, Natasha Irrera, Michele Navarra, Salvatore Corrao, Sebastiano Gangemi, Gianluca Bagnato, Versace A.G., Bitto A., Ioppolo C., Aragona C.O., La Rosa D., Roberts W.N., D'Angelo T., Cinquegrani A., Cirmi S., Irrera N., Navarra M., Corrao S., Gangemi S., and Bagnato G.
- Subjects
interstitial lung disease ,Medicine (General) ,R5-920 ,interleukins ,integumentary system ,systemic sclerosis ,IL-13 ,IL-33 ,General Medicine ,respiratory system ,skin and connective tissue diseases - Abstract
ObjectiveSystemic sclerosis (SSc) mortality is extremely variable in its internal organ involvement. Pulmonary fibrosis occurs in up to 30% of the cases. Animal models provide evidence that IL-33 is able to induce both cutaneous and pulmonary fibrosis via increased IL-13 and in SSc patients the levels of IL-33 correlate with skin fibrosis. Our aim was to test whether both IL-33 and IL-13 are higher in patients with diffuse SSc and interstitial lung disease (SSc-ILD) compared to SSc patients without ILD and healthy controls.MethodsSerum levels of IL-13 and IL-33 were measured in 30 SSc patients with diffuse disease and 30 healthy controls by enzyme-linked immunosorbent assay. The extent of pulmonary fibrosis was assessed according to HRCT Warrick score. Pulmonary function tests included lung diffusion capacity for carbon monoxide, forced vital capacity and total lung capacity.ResultsBoth IL-13 and IL-33 levels were increased in SSc patients compared to controls and significantly associated each other. DLco, FVC and TLC scores were inversely associated with IL-33 and IL-13 levels. Both IL-33 and IL-13 levels were significantly associated with the Warrick severity score and higher in the group of SSc patients with reduced pulmonary function compared to SSc patients with normal pulmonary function tests.ConclusionThe IL-13/IL-33 axis needs to be further explored in longitudinal studies of SSc-ILD patients to assess its validity as a biomarker and future treatment target, as does downstream mediator ST2.
- Published
- 2022
40. New-Onset Atrial Fibrillation and Early Mortality Rate in COVID-19 Patients: Association with IL-6 Serum Levels and Respiratory Distress
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Gianluca Bagnato, Egidio Imbalzano, Caterina Oriana Aragona, Carmelo Ioppolo, Pierpaolo Di Micco, Daniela La Rosa, Francesco Costa, Antonio Micari, Simona Tomeo, Natalia Zirilli, Angela Sciacqua, Tommaso D’Angelo, Irene Cacciola, Alessandra Bitto, Natasha Irrera, Vincenzo Russo, William Neal Roberts, Sebastiano Gangemi, Antonio Giovanni Versace, Bagnato, G., Imbalzano, E., Aragona, C. O., Ioppolo, C., Di Micco, P., La Rosa, D., Costa, F., Micari, A., Tomeo, S., Zirilli, N., Sciacqua, A., D'Angelo, T., Cacciola, I., Bitto, A., Irrera, N., Russo, V., Roberts, W. N., Gangemi, S., and Versace, A. G.
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Male ,Respiratory Distress Syndrome ,Interleukin-6 ,Risk Factor ,interleukin 6 ,COVID-19 ,General Medicine ,atrial fibrillation ,mortality risk ,Dyspnea ,Retrospective Studie ,Risk Factors ,Female ,Humans ,Retrospective Studies ,Atrial Fibrillation ,Human - Abstract
Background and objectives: COVID-19 is associated with an aberrant inflammatory response that may trigger new-onset cardiac arrhythmias. The aim of this study was to assess the mortality risk in hospitalized COVID-19 patients according to IL-6 serum levels and new-onset atrial fibrillation (AF) according to PaO2/FiO2 stratification. Materials and Methods: 175 COVID-19 patients (25 new-onset AF, 22 other types of AF and 128 no-AF) were included in this single-center, retrospective study; clinical and demographic data, vital signs, electrocardiograms and laboratory results were collected and analyzed. The primary outcome of the study was to evaluate the mortality rate in new-onset AF patients according to IL-6 serum levels and PaO2/FiO2 stratification. Results: The incidence of new-onset AF in the study population was 14.2%. Compared to the no-AF group, new-onset AF patients were older with a positive history of chronic kidney disease and heart failure, had higher IL-6, creatinine and urea serum levels whereas their platelet count was reduced. After PaO2/FiO2 stratification, 5-days mortality rate was higher in new-onset AF patients compared to patients with other types of AF and no-AF patients, and mortality risk increases 5.3 fold compared to no-AF (p = 0.0014) and 4.8 fold compared to other forms of AF (p = 0.03). Conclusions: New-onset AF is common in COVID-19 patients and is associated with increased IL-6 serum levels and early mortality. Further studies are needed to support the use of IL-6 as an early molecular target for COVID-19 patients to reduce their high rate of mortality.
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- 2022
41. Spectral CT for non-invasive evaluation of bladder cancer grade.
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Trimarchi R, Migliaccio N, Bucolo GM, Abate C, Aricò FM, Ascenti V, Portaluri A, Rossanese M, Zagami P, D'Angelo T, Piacentino F, Venturini M, and Ascenti G
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Objective: To investigate the potential role of dual-energy spectral computer tomography (CT) quantitative parameters in the definition of bladder cancer (BCa) pathological grading., Methods: This retrospective study evaluated the use of spectral CT imaging features for BCa. From 2021 to 2023, 63 patients with histologically-confirmed BCa diagnosis were examined at our Institution. The patients were pathologically divided, following international guidelines, into two groups: low-grade (n = 24) and high-grade urothelial carcinoma group (n = 39). The iodine concentrations (IC), the normalized iodine concentrations (NIC), and the slope of the spectrum curve (SLOPE) were calculated along with the measure of each lesion CT value on the monochromatic image from 40 to 120 keV. The diagnostic performance was assessed by Receiver operator characteristic curve (ROC) analysis., Results: The high-grade group showed significantly higher mean values of IC, SLOPE, and HU in 40 KeV monoenergetic images (VMI
40 HU). AUC values for NIC, SLOPE, IC, and VMI40 HU were 0,677, 0,745, 0,745, and 0,755 respectively. In multivariate logistic regression models with backward stepwise, including all quantitative parameters, only VMI40 HU remained statistically significant to correlate with high-grade tumors., Conclusion: Preliminary data shows that quantitative parameters of dual-energy spectral CT can be helpful to characterize low-grade and high-grade urothelial bladder tumors. The prediction of high-grade BCa with non-invasive methods (e.g. dlCT) can aid in early detection of muscle-invasive and worse prognostic tumors that need more aggressive and timely treatments, personalizing the management on the risk of recurrence., Competing Interests: Declarations Ethical approval All procedures performed in this retrospective study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent The requirement for informed consent was waived. Competing interests The authors declare no competing interests., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2024
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42. Dual-energy CT late arterial phase iodine maps for the diagnosis of acute non-occlusive mesenteric ischemia.
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D'Angelo T, Bucolo GM, Yel I, Koch V, Gruenewald LD, Martin SS, Alizadeh LS, Vogl TJ, Ascenti G, Lanzafame LRM, Mazziotti S, Blandino A, and Booz C
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- Humans, Male, Female, Aged, Middle Aged, Radiography, Dual-Energy Scanned Projection methods, Retrospective Studies, Acute Disease, Aged, 80 and over, Iodine, Sensitivity and Specificity, ROC Curve, Mesenteric Ischemia diagnostic imaging, Contrast Media, Tomography, X-Ray Computed methods
- Abstract
Purpose: To evaluate the diagnostic accuracy of dual-energy CT (DECT) iodine maps in comparison to conventional CT series for the assessment of non-occlusive mesenteric ischemia (NOMI)., Material and Methods: We evaluated data from 142 patients (72 men; 50.7%) who underwent DECT between 2018 and 2022, with surgically confirmed diagnosis of NOMI. One board-certified radiologist performed region of interest (ROI) measurements in bowel segments on late arterial (LA) and portal venous (PV) phase DECT iodine maps as well as LA conventional series, in both ischemic and non-ischemic bowel loops, using surgical reports as reference standard, and in a control group of 97 patients. Intra- and inter-reader agreement with a second board-certified radiologist was also evaluated. Receiver operating characteristic (ROC) curve analysis was performed to calculate the optimal threshold for discriminating ischemic from non-ischemic bowel segments. Subjective image rating of LA and PV iodine maps was performed., Results: DECT-based iodine concentration (IC) measurements showed significant differences in LA phase iodine maps between ischemic (median:0.72; IQR 0.52-0.91 mg/mL) and non-ischemic bowel loops (5.16; IQR 3.45-6.31 mg/ml) (P <.0001). IC quantification on LA phase revealed an AUC of 0.966 for the assessment of acute bowel ischemia, significantly higher compared to both IC quantification based on PV phase (0.951) and attenuation values evaluated on LA conventional CT series (0.828). Excellent intra-observer and strong inter-observer agreements were observed for the quantification of iodine concentration. Conversely, weak inter-observer agreement was noted for conventional HU assessments. The optimal LA phase-based IC threshold for assessing bowel ischemia was 1.34 mg/mL, yielding a sensitivity of 100% and specificity of 96.48%., Conclusion: Iodine maps based on LA phase significantly improve the diagnostic accuracy for the assessment of NOMI compared to conventional CT series and PV phase iodine maps., Competing Interests: Declarations Conflict of interest C.B. and I.Y have received speaking fees from Siemens Healthineers. T.D. and G.A. received speaking fees from Bracco and Philips. No support or funding was received for this project. The other authors have no potential conflict of interest to disclose. Consent to publish All authors provided their consent for publication of this study. The authors affirm that human research participants provided informed consent for publication of the radiological images. Ethical approval The study was conducted in accordance with the Declaration of Helsinki. Approval for this study was received by institutional review board at the University Hospital Frankfurt, with a waiver for informed consent of the patients due to the retrospective nature of our study (approval number: 2022–1391). Consent to participate A waiver for informed consent of the patients was provided by the IRB due to the retrospective and observational nature of our study., (© 2024. The Author(s).)
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- 2024
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43. Carotid artery assessment in dual-source photon-counting CT: impact of low-energy virtual monoenergetic imaging on image quality, vascular contrast and diagnostic assessability.
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Booz C, Bucolo GM, D'Angelo T, Mazziotti S, Lanzafame LRM, Yel I, Alizadeh LS, Gruenewald LD, Koch V, Martin SS, Dimitrova M, Goekduman A, Vogl TJ, Kaatsch HL, Overhoff D, and Waldeck S
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- Humans, Male, Female, Retrospective Studies, Middle Aged, Aged, Aged, 80 and over, Adult, Radiographic Image Interpretation, Computer-Assisted methods, Radiography, Dual-Energy Scanned Projection methods, Tomography, X-Ray Computed methods, Signal-To-Noise Ratio, Contrast Media, Computed Tomography Angiography methods, Carotid Arteries diagnostic imaging
- Abstract
Purpose: Preliminary dual-energy CT studies have shown that low-energy virtual monoenergetic (VMI) + reconstructions can provide superior image quality compared to standard 120 kV CTA series. The purpose of this study is to evaluate the impact of low-energy VMI reconstructions on quantitative and qualitative image quality, vascular contrast, and diagnostic assessability of the carotid artery in patients undergoing photon-counting CTA examinations., Materials and Methods: A total of 122 patients (67 male) who had undergone dual-source photon-counting CTA scans of the carotid artery were retrospectively analyzed in this study. Standard 120 kV CT images and low-keV VMI series from 40 to 100 keV with an interval of 15 keV were reconstructed. Quantitative analyses included the evaluation of vascular CT numbers, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). CT number measurements were performed in the common, external, and internal carotid arteries. Qualitative analyses were performed by three board-certified radiologists independently using five-point scales to evaluate image quality, vascular contrast, and diagnostic assessability of the carotid artery., Results: Mean attenuation, CNR and SNR values were highest in 40 keV VMI reconstructions (HU, 1362.32 ± 457.81; CNR, 33.19 ± 12.86; SNR, 34.37 ± 12.89) followed by 55-keV VMI reconstructions (HU, 736.94 ± 150.09; CNR, 24.49 ± 7.11; SNR, 26.25 ± 7.34); all three mean values at these keV levels were significantly higher compared with the remaining VMI series and standard 120 kV CT series (HU, 154.43 ± 23.69; CNR, 16.34 ± 5.47; SNR, 24.44 ± 7.14) (p < 0.0001). The qualitative analysis showed the highest rating scores for 55 keV VMI reconstructions followed by 40 keV and 70 keV VMI series with a significant difference compared to standard 120 kV CT images series regarding image quality, vascular contrast, and diagnostic assessability of the carotid artery (all comparisons, p < 0.01)., Conclusions: Low-keV VMI reconstructions at a level of 40-55 keV significantly improve image quality, vascular contrast, and the diagnostic assessability of the carotid artery compared with standard CT series in photon-counting CTA., Competing Interests: Declarations Conflict of interest C.B. and I.Y have received speaking fees from Siemens Healthineers. T.D. has received speaking fees from Bracco and Philips. No support or funding was received for this project. The other authors have no potential conflict of interest to disclose. Ethics approval Approval for this study was received by institutional review board at the University Hospital Frankfurt, with a waiver for informed consent of the patients due to the retrospective nature of our study (approval number: 2023–1708). Consent to participate A waiver for informed consent of the patients was provided by the IRB due to the retrospective and observational nature of our study. Consent to publish All authors provided their consent for publication of this study. The authors affirm that human research participants provided informed consent for publication of the radiological images., (© 2024. The Author(s).)
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- 2024
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44. Advanced Multimodality Cardiovascular Imaging of Supravalvular Aortic Stenosis in Williams-Beuren Syndrome.
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Micari A, Pergolizzi F, Pathan F, Booz C, Koch V, Chisari LM, Zito C, Mazziotti S, and D'Angelo T
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Competing Interests: None.
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- 2024
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45. Cardiovascular Magnetic Resonance Imaging of Takotsubo Syndrome: Evolving Diagnostic and Prognostic Perspectives.
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Cau R, Masala S, Manelli L, Porcu M, Scaglione M, D'Angelo T, Salgado R, and Saba L
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- Humans, Prognosis, Magnetic Resonance Imaging methods, Takotsubo Cardiomyopathy diagnostic imaging, Takotsubo Cardiomyopathy physiopathology, Takotsubo Cardiomyopathy diagnosis, Magnetic Resonance Imaging, Cine methods
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Takotsubo syndrome (TS) is a temporary form of left ventricular (LV) dysfunction characterized by a distinct pattern of LV impairment, often triggered by a physical or emotional stressful event. Historically, TS was considered a benign condition due to its prompt restoration of myocardial function and generally excellent outcomes. However, recent studies have shown that complications similar to those seen after myocardial infarction can occur, necessitating careful monitoring of these patients. Among noninvasive imaging techniques, cardiovascular magnetic resonance (CMR) is becoming increasingly important in evaluating patients with TS. CMR offers a unique ability to noninvasively assess myocardial tissue characteristics, allowing for detecting the typical features of TS, such as specific wall motion abnormalities and myocardial edema. Beyond its well-established diagnostic utility in the clinical management of TS, CMR has also proven valuable in prognosis and risk stratification for these patients. Advances in CMR, including myocardial strain and parametric mapping have expanded its role in the diagnosis, prognosis, and follow-up of these patients. This review aims to provide a comprehensive overview of the potential applications of CMR in the diagnostic and prognostic evaluation of TS patients. It explores the emerging use of novel CMR imaging biomarkers that may enhance diagnosis, improve prognostic accuracy, and contribute to the overall management of these patients., (© 2024 Wiley Periodicals LLC.)
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- 2024
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46. Accuracy and time efficiency of a novel deep learning algorithm for Intracranial Hemorrhage detection in CT Scans.
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D'Angelo T, Bucolo GM, Kamareddine T, Yel I, Koch V, Gruenewald LD, Martin S, Alizadeh LS, Mazziotti S, Blandino A, Vogl TJ, and Booz C
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- Humans, Retrospective Studies, Male, Female, Middle Aged, Adult, Aged, Algorithms, Brain Injuries, Traumatic diagnostic imaging, Sensitivity and Specificity, Time Factors, Aged, 80 and over, Deep Learning, Tomography, X-Ray Computed methods, Intracranial Hemorrhages diagnostic imaging
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Purpose: To evaluate a deep learning-based pipeline using a Dense-UNet architecture for the assessment of acute intracranial hemorrhage (ICH) on non-contrast computed tomography (NCCT) head scans after traumatic brain injury (TBI)., Materials and Methods: This retrospective study was conducted using a prototype algorithm that evaluated 502 NCCT head scans with ICH in context of TBI. Four board-certified radiologists evaluated in consensus the CT scans to establish the standard of reference for hemorrhage presence and type of ICH. Consequently, all CT scans were independently analyzed by the algorithm and a board-certified radiologist to assess the presence and type of ICH. Additionally, the time to diagnosis was measured for both methods., Results: A total of 405/502 patients presented ICH classified in the following types: intraparenchymal (n = 172); intraventricular (n = 26); subarachnoid (n = 163); subdural (n = 178); and epidural (n = 15). The algorithm showed high diagnostic accuracy (91.24%) for the assessment of ICH with a sensitivity of 90.37% and specificity of 94.85%. To distinguish the different ICH types, the algorithm had a sensitivity of 93.47% and a specificity of 99.79%, with an accuracy of 98.54%. To detect midline shift, the algorithm had a sensitivity of 100%. In terms of processing time, the algorithm was significantly faster compared to the radiologist's time to first diagnosis (15.37 ± 1.85 vs 277 ± 14 s, p < 0.001)., Conclusion: A novel deep learning algorithm can provide high diagnostic accuracy for the identification and classification of ICH from unenhanced CT scans, combined with short processing times. This has the potential to assist and improve radiologists' ICH assessment in NCCT scans, especially in emergency scenarios, when time efficiency is needed., (© 2024. The Author(s).)
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- 2024
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47. The mental and emotional status after radical cystectomy and different urinary diversion orthotopic bladder substitution versus external urinary diversion after radical cystectomy: A propensity score-matched study.
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Giuseppe P, Francesco Pio B, Eros S, Emilio S, Koosha MS, Pierluigi R, Filippo G, Battista FG, Francesco R, Marco C, Angelo T, Nazario F, and Marco R
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Objectives: The quality of life in patients undergoing radical cystectomy and urinary diversion is gaining importance. Nowadays a broad consensus about the best urinary diversion does not exist. This study presents an all-round analysis of the impact of two types of urinary diversion on life's psycho-social aspects in patients undergoing radical cystectomy., Methods: This is an observational, single-centre, prospective study. Eligible participants underwent radical cystectomy and urinary diversion for bladder cancer in our department from January 2020 and February 2024. Of 130 included patients, 90 (45 with Bricker's ureteroileocutaneostomy and 45 received orthotopic bladder replacement) patients were matched and the study groups were well balanced for the baseline-matched variables. Patients completed 4 questionnaires (EORTC QLQ-C30, PGWBI, HADS, PSQI) at three different times: before the surgical procedure, and at 3 and 12 months., Results: Time shows a statistically significant effect (p < 0.0005) on four of the five functional scales explored (Physical Functioning, Role Functioning, Emotional Functioning, Social Functioning), and for all the nine symptoms/items' scales (p < 0.0005) and the Global Health Status (p = 0.003) in EORTC QLQ-C30. Neobladder's group shows a statistically significant improvement on the scales of Physical Functioning, Role Functioning, and Social Functioning, and for symptoms of nausea (p = 0.0027), pain (p = 0.0005), dyspnea (p = 0.012), insomnia (p = 0.004), constipation (p = 0.003)., Conclusion: We do not find a better urinary diversion in absolute terms. Neobladder obtained better results only for specific items and features. The urinary diversion's choice must be made in concert by the patient, the caregiver, and health professionals with adequate counseling., (© 2024 The Author(s). International Journal of Urology published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Urological Association.)
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- 2024
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48. Standardization of Dual-Energy CT Iodine Uptake of the Abdomen and Pelvis: Defining Reference Values in a Big Data Cohort.
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Yel I, Booz C, D'Angelo T, Koch V, Gruenewald LD, Eichler K, Gökduman A, Giardino D, Gaeta M, Mazziotti S, Herrmann E, Vogl TJ, Mahmoudi S, and Lanzafame LRM
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Background: To establish dual-energy-derived iodine density reference values in abdominopelvic organs in a large cohort of healthy subjects. Methods : 597 patients who underwent portal venous phase dual-energy CT scans of the abdomen were retrospectively enrolled. Iodine distribution maps were reconstructed, and regions of interest measurements were placed in abdominal and pelvic structures to obtain absolute iodine values. Subsequently, normalization of the abdominal aorta was conducted to obtain normalized iodine ratios. The values obtained were subsequently analyzed and differences were investigated in subgroups defined by sex, age and BMI. Results : Overall mean iodine uptake values and normalized iodine ratios ranged between 0.31 and 6.08 mg/mL and 0.06 and 1.20, respectively. Women exhibited higher absolute iodine concentration across all organs. With increasing age, normalized iodine ratios mostly tend to decrease, being most significant in the uterus, prostate, and kidneys ( p < 0.015). BMI was the parameter less responsible for variations in iodine concentrations; normal weighted patients demonstrated higher values of both absolute and normalized iodine. Conclusions : Iodine concentration values and normalized iodine ratios of abdominal and pelvic organs reveal significant gender-, age-, and BMI-related differences, underscoring the necessity to integrate these variables into clinical practice.
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- 2024
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49. Potential of Dual-Energy CT-Based Collagen Maps for the Assessment of Disk Degeneration in the Lumbar Spine.
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Mahmoudi S, Gruenewald LD, Koch V, Bernatz S, Martin SS, Engelskirchen L, Radic I, Bucolo G, D'Angelo T, Gotta J, Mader C, Dos Santos DP, Scholtz JE, Gruber-Rouh T, Eichler K, Vogl TJ, Booz C, and Yel I
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- Humans, Female, Male, Middle Aged, Aged, Adult, Retrospective Studies, Aged, 80 and over, Reproducibility of Results, Young Adult, Sensitivity and Specificity, Intervertebral Disc Degeneration diagnostic imaging, Lumbar Vertebrae diagnostic imaging, Collagen, Tomography, X-Ray Computed methods, Magnetic Resonance Imaging methods
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Rationale and Objectives: Lumbar disk degeneration is a common condition contributing significantly to back pain. The objective of the study was to evaluate the potential of dual-energy CT (DECT)-derived collagen maps for the assessment of lumbar disk degeneration., Patients and Methods: We conducted a retrospective analysis of 127 patients who underwent dual-source DECT and MRI of the lumbar spine between 07/2019 and 10/2022. The level of lumbar disk degeneration was categorized by three radiologists as follows: no/mild (Pfirrmann 1&2), moderate (Pfirrmann 3&4), and severe (Pfirrmann 5). Recall (sensitivity) and accuracy of DECT collagen maps were calculated. Intraclass correlation coefficient (ICC) was used to evaluate inter-reader reliability. Subjective evaluations were performed using 5-point Likert scales for diagnostic confidence and image quality., Results: We evaluated a total of 762 intervertebral disks from 127 patients (median age, 69.7 (range, 23.0-93.7), female, 56). MRI identified 230 non/mildly degenerated disks (30.2%), 484 moderately degenerated disks (63.5%), and 48 severely degenerated disks (6.3%). DECT collagen maps yielded an overall accuracy of 85.5% (1955/2286). Recall (sensitivity) was 79.3% (547/690) for the detection of no/mild lumbar disk degeneration, 88.7% (1288/1452) for the detection of moderate disk degeneration, and 83.3% (120/144) for the detection of severe disk degeneration (ICC=0.9). Subjective evaluations of DECT collagen maps showed high diagnostic confidence (median 4) and good image quality (median 4)., Conclusion: The use of DECT collagen maps to distinguish different stages of lumbar disk degeneration may have clinical significance in the early diagnosis of disk-related pathologies in patients with contraindications for MRI or in cases of unavailability of MRI., Competing Interests: Declaration of Competing Interest The authors of this manuscript declare relationships with the following companies: I.Y. received a speaking fee from Siemens Healthineers. C.B. received speaking fees from Siemens Healthineers. D.P. received speaker fees from Bayer AG, consulting fees for Cook Medical and author fees for AMBOSS GmbH. The other authors have no conflict of interest to disclose., (Copyright © 2024 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.)
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- 2024
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50. Biomechanical Assessment of Liver Integrity: Prospective Evaluation of Mechanical Versus Acoustic MR Elastography.
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Koch V, Gotta J, Chernyak V, Cengiz D, Torgashov K, Eichler K, Vilgrain V, Martin SS, Ziegengeist NS, Konrad P, Booz C, Yel I, D'Angelo T, Mahmoudi S, Scholtz JE, Bernatz S, Alizadeh LS, Cimprich M, Solim LA, Thalhammer A, Gruber-Rouh T, Hammerstingl RM, Zeuzem S, Finkelmeier F, Pathil-Warth A, Onay M, Kinzler MN, Darwish O, Annio G, Taylor SA, Wild P, Dahmer I, Herrmann E, Almansour H, Vogl TJ, Gruenewald LD, and Sinkus R
- Abstract
Background: Magnetic resonance elastography (MRE) can quantify tissue biomechanics noninvasively, including pathological hepatic states like metabolic dysfunction-associated steatohepatitis., Purpose: To compare the performance of 2D/3D-MRE using the gravitational (GT) transducer concept with the current commercial acoustic (AC) solution utilizing a 2D-MRE approach. Additionally, quality index markers (QIs) were proposed to identify image pixels with sufficient quality for reliably estimating tissue biomechanics., Study Type: Prospective., Population: One hundred seventy participants with suspected or confirmed liver disease (median age, 57 years [interquartile range (IQR), 46-65]; 66 females), and 11 healthy volunteers (median age, 31 years [IQR, 27-34]; 5 females)., Field Strength/sequence: Participants were scanned twice at 1.5 T and 60 Hz vibration frequency: first, using AC-MRE (2D-MRE, spin-echo EPI sequence, 11 seconds breath-hold), and second, using GT-MRE (2D- and 3D-MRE, gradient-echo sequence, 14 seconds breath-hold)., Assessment: Image analysis was performed by four independent radiologists and one biomedical engineer. Additionally, superimposed analytic plane shear waves of known wavelength and attenuation at fixed shear modulus were used to propose pertinent QIs., Statistical Tests: Spearman's correlation coefficient (r) was applied to assess the correlation between modalities. Interreader reproducibility was evaluated using Bland-Altman bias and reproducibility coefficients. P-values <0.05 were considered statistically significant., Results: Liver stiffness quantified via GT-2D/3D correlated well with AC-2D (r ≥ 0.89 [95% CI: 0.85-0.92]) and histopathological grading (r ≥ 0.84 [95% CI: 0.72-0.91]), demonstrating excellent agreement in Bland-Altman plots and between readers (κ ≥ 0.86 [95% CI: 0.81-0.91]). However, GT-2D showed a bias in overestimating stiffness compared to GT-3D. Proposed QIs enabled the identification of pixels deviating beyond 10% from true stiffness based on a combination of total wave amplitude, temporal sinusoidal nonlinearity, and wave signal-to-noise ratio for GT-3D., Conclusion: GT-MRE represents an alternative to AC-MRE for noninvasive liver tissue characterization. Both GT-2D and 3D approaches correlated strongly with the established commercial approach, offering advanced capabilities in abdominal imaging compared to AC-MRE., Evidence Level: 1 TECHNICAL EFFICACY: Stage 2., (© 2024 The Author(s). Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.)
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- 2024
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