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Your search keyword '"Fabrizio Gazzoli"' showing total 4 results
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4 results on '"Fabrizio Gazzoli"'

2. Response to acute vasodilator challenge and haemodynamic modifications after MitraClip in patients with functional mitral regurgitation and pulmonary hypertension

Author

Alessandro Mandurino-Mirizzi, Andrea Munafò, Claudia Raineri, Giulia Magrini, Romina Frassica, Luca Arzuffi, Laura Scelsi, Annalisa Turco, Marco Ferlini, Fabrizio Gazzoli, Maurizio Ferrario, Stefano Ghio, Luigi Oltrona-Visconti, and Gabriele Crimi

Subjects
Cardiac Catheterization, Treatment Outcome, Hypertension, Pulmonary, Vasodilator Agents, Hemodynamics, Humans, Mitral Valve, Mitral Valve Insufficiency, General Medicine, Cardiology and Cardiovascular Medicine, Critical Care and Intensive Care Medicine
Abstract

The effectiveness of transcatheter edge-to-edge repair (TEER) in patients with functional mitral regurgitation (FMR) and pulmonary hypertension (PH) is still debated and pre-procedural predictors of haemodynamic improvement after TEER in this setting are currently unknown. We investigated whether normalization of pulmonary artery wedge pressure (PAWP) in response to sodium nitroprusside (SNP) during baseline right heart catheterization might be predictive of a favourable haemodynamic response to MitraClip in patients with FMR and PH. Among 22 patients enrolled, 13 had a positive response to SNP (responders), nine were non-responders. At 6-months follow-up, responders showed a 33% reduction in PAWP and a 25% reduction in mean pulmonary artery pressure (PAP) (P = 0.002 and 0.004, respectively); no significant change occurred in non-responders. In patients with FMR and PH, pre-procedural vasodilator challenge with SNP may help define patients who may have haemodynamic improvement after TEER.

Published
2022
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3. Early surgical aortic valve replacement in asymptomatic patients with severe aortic stenosis: a systematic review and meta-analysis

Author

Marco Ferlini, Andrea Raffaele Munafò, Giuseppe Lanzillo, Marco Aiello, Fabrizio Gazzoli, Alessandro Mandurino Mirizzi, Giulia Magrini, Stefano Pelenghi, and Luigi Oltrona Visconti

Subjects
Heart Valve Prosthesis Implantation, Transcatheter Aortic Valve Replacement, Treatment Outcome, Risk Factors, Aortic Valve, Heart Valve Prosthesis, Humans, General Medicine, Aortic Valve Stenosis, Cardiology and Cardiovascular Medicine
Published
2022

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