40 results on '"Facial swelling"'
Search Results
2. The Use of Platelet-rich-fibrin in Lower Third Molar Surgery.
- Author
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Amerigo Giudice, Professor
- Published
- 2023
3. Can concentrated growth factor prevent postoperative complications of impacted third molar surgery? A split-mouth randomized double-blind trial.
- Author
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Huang, Cheng and Xu, Yuanzhi
- Abstract
Objectives: The purpose of the present study was to evaluate the effect of concentrated growth factor (CGF) on prevention of postoperative complications in the impacted third molar extraction. Materials and methods: A total of 25 healthy patients with symmetrical bilaterally impacted third molars (50 extraction sites) were enrolled in this split-mouth, randomized, double-blind clinical trial. Third molar extractions were performed in both sites of the mandible at the same appointment. Randomization was performed using a coin toss to choose the test and control sites. CGF was placed in the extraction socket and the socket was sutured (test group), while the contralateral socket was only sutured (control group). Each patient acted as their own control. The primary outcome were pain assessed by visual analog scale (VAS) and facial swelling on the1st, 3rd and 7th postoperative days. The secondary outcomes were bone healing in extraction sockets through alveolar bone height (ABH) and alveolar bone density (ABD) evaluated by cone beam computed tomography (CBCT) immediately after extraction and in the 3rd and 6th months. Results: Twenty-five patients (12 female, 13 male; mean age 29.17) with bilateral impacted third molars participated in the study. A statistically significant reduction in pain was determined on the 3rd and 7th postoperative days in the CGF sites compared to the control sites while no statistically significant difference was found between the groups on the 1st postoperative day (3rd day, p = 0.009; 7th day, p = 0.039). There were no statistically significant differences in facial swelling and bone healing between the test and control groups at different time intervals, although the data obtained were slightly favoring the CGF group (p > 0.05). There were no serious adverse effects such as infection, alveolitis, paraesthesia, fracture through the follow-up period in all of the cases. Conclusion: The study has demonstrated the effect of CGF on relieving the severity of pain after the third molar extraction. Clinical relevance: Placement of CGF in the extraction socket could relieve postoperative pain and reduce patient discomfort after the third molar extraction. CGF is recommended during the third molar extraction due to its good biological effects, low cost and simple preparation procedures. Trial Registration Number: ChiCTR2300077819. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Effect of Pre-emptive Dose of Prednisone Versus Placebo in Impacted Third Molar Surgery
- Author
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Amerigo Giudice, Professor
- Published
- 2023
5. Reduction of Post-Surgical Facial Edema Following Bromelain and Coumarin Intake in Traumatology: A Prospective Study with 100 Patients.
- Author
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Consorti, Giuseppe, Monarchi, Gabriele, Paglianiti, Mariagrazia, Betti, Enrico, and Balercia, Paolo
- Subjects
- *
BROMELIN , *TRAUMATOLOGY , *ORTHOPEDIC shoes , *ORAL drug administration , *EDEMA , *PINEAPPLE , *LONGITUDINAL method , *MAXILLOFACIAL surgery - Abstract
Background: Bromelain and coumarins are recognized as safe and effective therapeutic agents, used by individuals to treat ailments such as postoperative edema, inflammation and other diseases. Bromelain has been proven to be well absorbed by the body after oral administration, and it has no major side effects even after prolonged use. The purpose of this study is to evaluate the effectiveness of bromelain and other nutraceuticals in reducing post-surgical swelling, pain and the need of anti-inflammatory drugs in maxillofacial post-traumatic surgery. Methods: This prospective open-label study was conducted on patients undergoing surgery for trauma of the maxillofacial area. One hundred patients were selected and divided into two groups: one group who underwent therapy with bromelain, Aesculus hippocastanum and Melilotus officinalis and a control group that was not given the drug in postoperative therapy. Results: Patients in the experimental group showed a reduction of edema in the first and second postoperative weeks, a faster complete reduction of facial edema and a lower reduction in maximum mouth opening and needed less anti-inflammatory therapy to control pain. Conclusions: These findings seem to provide evidence that Brovas® may be effective in improving postoperative edema outcomes in patients undergoing surgical treatment of facial fractures. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
6. Peculiar Presentation: Dirofilariasis Unveiled in the Temporalis Muscle of a Teenager
- Author
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Moideen, Sanu P. and Jose, Tarun Babu
- Published
- 2024
- Full Text
- View/download PDF
7. Comparative Evaluation of Postoperative Facial Swelling and Occlusion in Orthognathic Treatment with Clear Aligners versus Fixed Orthodontic Appliances: A Systematic Review.
- Author
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Rosenberg, Stacy Ann, Rossouw, P. Emile, Barmak, Basir A., Michelogiannakis, Dimitrios, and Javed, Fawad
- Subjects
ORTHODONTIC appliances ,ORTHOGNATHIC surgery ,EDEMA ,DATABASE searching - Abstract
The purpose of this systematic review was to assess the postoperative facial swelling (FS) and occlusion attained with clear aligner therapy (CAT) and fixed orthodontic therapy (OT) after orthognathic surgery (OS). The focused question was "Is there a difference in postoperative FS and occlusion attained with CAT and fixed OT after OS?" Indexed databases were searched up to and including October 2023 using different keywords. Original clinical studies that compared postoperative FS and occlusion attained with CAT and fixed OT after OS were included. Risk of bias (RoB) and quality of evidence were also assessed. Four retrospective studies were included. One study reported no difference in postoperative FS among patients that underwent CAT or fixed OT after OS. In one study, patients treated with CAT demonstrated less FS in the first post-surgical week than individuals that underwent fixed OT. In one study, postoperative occlusion was comparable among patients that underwent CAT or fixed OT, whereas in another, postoperative occlusion was better in patients that underwent fixed OT than CAT. All studies had a moderate RoB and none of the investigations were based on power-adjusted data. Based upon the sparsity and questionable quality of available evidence, there is a need to render a firm conclusion. However, it seems that CAT and fixed OT are comparable in relation to postoperative occlusion and FS after OS. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
8. Evaluation of the effectiveness of tube drain on postoperative discomfort in mandibular third molar surgery: prospective randomized split-mouth study.
- Author
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Mariani, Pierluigi, Menditti, Dardo, Russo, Diana, and Laino, Luigi
- Subjects
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THIRD molars , *DENTAL extraction , *SURGICAL flaps , *IMPACTION of teeth , *PAIN measurement , *TUBES - Abstract
The present randomized split-mouth study aimed to investigate the clinical effectiveness of postoperative discomfort of the use of a surgical drain after lower third molar extraction. It was conducted a prospective randomized split-mouth study involving 30 patients with bilateral symmetric lower third molar. Each patient underwent two operations for the extraction of impacted teeth: test site (tube drain) and control site (conventional total closure of surgical flap), resulting in 30 cases in the test group, and 30 cases in the control group. Pain, swelling, and mouth opening were evaluated immediately before the surgeries, after 1, 3 and 7 days postoperatively in both groups. Data were analyzed with non-parametric test (Kruskal-Wallis test and the post hoc Dun test, and Wilcoxon matched-pairs signed rank test). Facial swelling (p <.001) was significantly less in test group compared with the control group on all examined days. Trismus is significantly reduced only on the third day (p <.001); Pain measurements did not differ statistically significantly between the two groups on all post-operative days (p >.05). The use of the tube drain reduced facial swelling and trismus, but had no influence on the subjective perception of postoperative pain. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
9. The effects of Kinesio tapes on facial swelling following bimaxillary orthognathic surgery in the supraclavicular region
- Author
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Mohsen Golkar, Anita Taheri, Mostafa Alam, Yasin Asadi, and Seied Omid Keyhan
- Subjects
Kinesio tapes ,Facial swelling ,Orthognathic surgery ,Supraclavicular region ,Dentistry ,RK1-715 ,Surgery ,RD1-811 - Abstract
Abstract Background Several osteotomies are required for orthognathic surgery to reposition the jaws correctly. This study aimed to evaluate whether Kinesiotaping can reduce swelling, pain, and trismus following orthognathic surgery of the facial skull. Materials and methods The present study consists of two phases. In the split-mouth phase, 16 skeletal class III patients underwent Bimax Orthognathic surgery, and Kinesiological tape (KT) was applied on one half of the face. In the prospective case–control phase, 30 patients were divided into two groups. Kinesio tape was applied on both sides of the face of the Kinesio group, and pressure dressing and ice therapy were used for the second group. The tape was parallel to the lower border of the mandible along its entire length, tangent to the labial commissure area on the studied side. The tape was placed in place for 5 days. Edema was evaluated by measuring the distance from the menton to the lower edge of the tragus. The maximum mouth-opening trismus was evaluated, and the VAS index was used to evaluate pain. Results There was evidence of swelling reduction after KT; within the same study, differences between the left and right sides as well as for the same side were statistically significant (p
- Published
- 2023
- Full Text
- View/download PDF
10. The effect of hyaluronic acid addition to collagen in reducing the trismus and swelling after surgical extraction of impacted lower third molars: a split-mouth, randomized controlled study.
- Author
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Kokash, Moemeneh, Darwich, Khaldoun, and Ataya, Jawdat
- Subjects
- *
THIRD molars , *HYALURONIC acid , *TRISMUS , *MOLARS , *COLLAGEN , *DENTAL extraction - Abstract
Background: Removal of impacted third molars is associated with postoperative complications such as pain, swelling, ecchymosis, trismus, infection, and hematoma. Thus, contemporary surgery aims to reduce complications by applying collagen or hyaluronic acid in the socket after extracting the impacted mandibular third molars. This study aimed to study the efficacy of hyaluronic acid (HA) addition to collagen, compared to collagen application alone, on the magnitude of swelling and trismus following impacted mandibular third molar surgery. Methods and materials: A total of 40 impacted molars of 20 participants who had completely bilateral impacted lower third molars were enrolled in this split-mouth, randomized, clinical trial. Randomization was carried out by two opaque envelops; two materials were applied topically in the socket collagen alone or with hyaluronic. The postoperative mouth-opening limitation and swelling rate were assessed on the third and seventh days after the extraction. Results: The mean age was 22.7 ± 3.079 years (75% female and 25% male). Regarding the rate of trismus, the test sides had less values than the control sides on 3rd days (44.03 ± 12.8 vs. 52.14 ± 13.7) and 7th days (19.22 ± 12.8 vs. 32.45 ± 15.3) postoperatively but the difference is only significant on the seventh day (P = 0.005). The swelling scores of the hyaluronic acid addition group were significantly lesser than those of the collagen alone group on the third and the seventh day (P < 0.05) except for the lateral canthus to the angulus mandibulae on the third day (P = 0.133). Conclusion: Adding hyaluronic acid to collagen could effectively reduce the severity of facial swelling and trismus following surgical extraction of impacted lower third molars. Statement of clinical relevance : Swelling and trismus are the most sequela following impacted third molar surgical extraction. This study showed that applying hyaluronic acid with collagen can reduce the severity of facial swelling and trismus which could be useful in surgeons' daily practice. We should mention that this original article has a preprint edition (44). [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
11. EVALUATION OF ANTI-INFLAMMATORY EFFICACY OF ASCORBIC ACID AFTER THIRD MOLAR SURGERY.
- Author
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Fatima, Maryam, Farhat, Kulsoom, Ali, Shabana, Noor, Mudassar, Usman, Chaudhary Muhammad, and Gilani, Fauzia Fatima
- Subjects
ANTI-inflammatory agents ,THIRD molar surgery ,THERAPEUTIC use of vitamin C ,AMOXICILLIN ,CLAVULANIC acid - Abstract
Background: Abstraction of wisdom teeth or impacted third molar under local anaesthesia is one of the most frequent interventions by an oral and maxillofacial surgeon. The abstraction of the third molar is usually followed by the release of liberation and consequent trismus, pain, and swelling due to the area of the third molar being highly vascularized and rich in loose connective tissue. Objective of the study was to evaluate the anti-inflammatory effect of ascorbic acid following surgical extraction of the third molar. Methods: The current study was carried out Armed Forces Institute of Dentistry, Rawalpindi, from October to December 2022. This was a cross-sectional observational study. Fifty participants who required surgical extraction of the impacted third molar were included in the study via non-probability purposive sampling and were segregated equally into two groups, i.e., Group A and Group B, comprising twenty-five participants in each group. Group A received amoxicillin with clavulanic acid (625 mg) thrice a day and metronidazole (400 mg) twice daily. In comparison, Group B received amoxicillin with clavulanic acid (625 mg) thrice daily, ascorbic acid (500 mg) twice daily, and metronidazole (400 mg) twice daily. Both groups received naproxen sodium as per requirement (550 mg). Pain, facial swelling, and C reactive protein concentration were evaluated until the 7
th postoperative day. Results: There was a reduction in pain and facial swelling in both groups, but in the ascorbic acid group, there was more reduction in pain and facial swelling compared to the control group. However, the difference between the two groups in reducing pain and facial swelling was statistically significant (p<0.01). There was a reduction in CRP in both groups, but in the ascorbic acid group, there was more reduction in CRP 2.35 (1.60-5.30) compared to the control group 2.6 (0.86-5.03). However, the difference between the two groups in reducing C reactive protein concentration was statistically insignificant (p>0.05). Conclusion: Our study concluded that ascorbic acid significantly reduced inflammation and C reactive protein, so ascorbic acid should be used as an adjuvant supplement with other conventional drugs. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
- View/download PDF
12. Reduction of Post-Surgical Facial Edema Following Bromelain and Coumarin Intake in Traumatology: A Prospective Study with 100 Patients
- Author
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Giuseppe Consorti, Gabriele Monarchi, Mariagrazia Paglianiti, Enrico Betti, and Paolo Balercia
- Subjects
facial swelling ,bromelain ,post-surgical edema ,pain ,traumatology ,facial trauma ,Medicine - Abstract
Background: Bromelain and coumarins are recognized as safe and effective therapeutic agents, used by individuals to treat ailments such as postoperative edema, inflammation and other diseases. Bromelain has been proven to be well absorbed by the body after oral administration, and it has no major side effects even after prolonged use. The purpose of this study is to evaluate the effectiveness of bromelain and other nutraceuticals in reducing post-surgical swelling, pain and the need of anti-inflammatory drugs in maxillofacial post-traumatic surgery. Methods: This prospective open-label study was conducted on patients undergoing surgery for trauma of the maxillofacial area. One hundred patients were selected and divided into two groups: one group who underwent therapy with bromelain, Aesculus hippocastanum and Melilotus officinalis and a control group that was not given the drug in postoperative therapy. Results: Patients in the experimental group showed a reduction of edema in the first and second postoperative weeks, a faster complete reduction of facial edema and a lower reduction in maximum mouth opening and needed less anti-inflammatory therapy to control pain. Conclusions: These findings seem to provide evidence that Brovas® may be effective in improving postoperative edema outcomes in patients undergoing surgical treatment of facial fractures.
- Published
- 2024
- Full Text
- View/download PDF
13. Three-dimensional facial swelling evaluation of piezo-electric vs conventional drilling bur surgery of impacted lower third molar: a randomized clinical trial.
- Author
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Caputo, A., Rubino, E., Marcianò, A., Peditto, M., Bellocchio, A. M., Nucera, R., and Oteri, G.
- Subjects
STRUCTURAL models ,OSTEOTOMY ,PIEZOSURGERY ,THIRD molars ,SURGICAL complications ,SMARTPHONES ,FACE ,TREATMENT effectiveness ,RANDOMIZED controlled trials ,EDEMA - Abstract
Background: Among the post-surgical complications of lower wisdom teeth surgery, swelling is considered by patients one of the most impairing, with both social and biological influences and impacting patients' quality of life. Aim of the study was to evaluate the swelling following the osteotomy when performed with drilling burs versus piezo-electric instruments in the mandibular impacted third molar extraction, using a facial reconstruction software. Materials and methods: A randomized, split-mouth, single-blind study was conducted on patients, ranging between 18 and 40 years of age, requiring lower third molars extraction and referred at the Oral Surgery Unit of the School of Dentistry of the University of Messina. Twenty-two patients were recruited during an 8 months period according to the following criteria: good general health conditions; bilateral, symmetrical, impacted third molars; no use of medication that would influence or alter wound healing; no temporomandibular joint disorder history; no smoking. All patients underwent bilateral surgical removal. For each patient, a facial scan was obtained prior to the surgical procedures. The two extractions were conducted performing, in a randomized way, osteotomy with rotatory burs or use of piezo surgical instruments. Facial scans were repeated at 3 and 7 days after the surgical procedures. Volumetric differences were calculated via superimposition using a dedicated software. The data obtained were processed using paired t-test. Results: The results obtained from our study showed no significant differences between two groups regarding post-operative swelling. To the best of our knowledge, this study represents the first experience of using an objective method that can be reproducible on the collection of patients' clinical parameters. Conclusions: The 3D digital analysis, in the evaluation of facial swelling, is a technique of simple application, objective, reproducible, reliable, decreasing the variables of error. Based on these data, it is possible to conclude that piezo surgery is a safe way for performing the osteotomies during third molar surgery. However, regarding the post-operative swelling, it does not show an advantage over classical rotary instruments. Trial registration: Registered on ClinicalTrials.gov (ID: NCT05488028, on 04/08/2022). Approved by Ethical Committee of Messina: (ID 01–2020, on 27/04/2020). [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
14. Multisystemic Enterococcosis in Brown Anoles (Anolis sagrei) from Florida, USA.
- Author
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Caudill, Megan, Logan, Tracey D., Childress, April, Guzman-Vargas, Veronica, Enge, Kevin M., Shender, Lisa A., and Ossiboff, Robert J.
- Abstract
Beginning in July 2019, numerous free-ranging brown anoles (Anolis sagrei), an invasive lizard species in Florida, USA, were reported with large, soft, subcutaneous masses and disfiguring facial swellings. Postmortem evaluations of six affected animals, including cytology, histology, and electron microscopy, identified the presence of myriad chain-forming coccoid bacteria surrounded by a prominent clear capsule and abundant lightly basophilic matrix material with minimal associated granulomatous inflammation and effacement of normal tissue. Standard PCR and sequencing of the lesions revealed 100% nucleotide identity to Enterococcus lacertideformus. This bacterium was first observed in 2014 as the cause of a severe, multisystemic infection in several species of lizards (geckos and skinks) on Christmas Island, an Australian external territory in the Indian Ocean. Previously, analysis of E. lacertideformus had been hindered by an inability to grow the bacterium in standard culture conditions. We successfully cultured the organism on primary anole kidney cells. Given the growing recognition of host species diversity and geographic distribution noted for this organism, there is potential concern for spread to native North American lizards, especially the green anole (Anolis carolinensis), whose population numbers have apparently decreased due to introduced brown anoles. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
15. Facial Swelling After Dental Work Done: A Case of Ludwig's Angina.
- Author
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Gonzalez, Juan Manuel, McGhee, Stephen, Nadeau, Catherine, and Ortega, Johis
- Subjects
- *
ORAL disease diagnosis , *CLINICAL pathology , *DISEASE progression , *PAIN , *ORAL diseases , *DENTAL care , *DIFFERENTIAL diagnosis , *FACE , *NECK , *DECISION making in clinical medicine , *EDEMA , *JAWS , *ANTIBIOTICS - Abstract
Ludwig's angina is a fast-spreading cellulitis located on the floor of the oropharynx and neck (Tami, Othman, Sudhakar, & McKinnon, 2020). Patients may present with a wide range of symptoms depending on the severity of the condition (Reynolds & Chow, 2007). Emergency nurse practitioners need to promptly identify, diagnose, and treat patients with this problem, with close attention to the patient's airway. A compromised airway is the leading cause of mortality from this condition (McDonnough et al., 2019). The diagnosis is generally made with a comprehensive history and physical examination, laboratory values, and imaging studies such as computer tomography (Bridwell, Gottlieb, Koyfman, & Long, 2021). Management includes admission to the hospital, broad-spectrum antibiotics, and specialist surgical consultation (Bridwell et al., 2021). [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
16. Comparative Evaluation of Postoperative Facial Swelling and Occlusion in Orthognathic Treatment with Clear Aligners versus Fixed Orthodontic Appliances: A Systematic Review
- Author
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Stacy Ann Rosenberg, P. Emile Rossouw, Basir A. Barmak, Dimitrios Michelogiannakis, and Fawad Javed
- Subjects
clear aligner therapy ,clear aligners ,complications ,edema ,facial swelling ,fixed orthodontic therapy ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The purpose of this systematic review was to assess the postoperative facial swelling (FS) and occlusion attained with clear aligner therapy (CAT) and fixed orthodontic therapy (OT) after orthognathic surgery (OS). The focused question was “Is there a difference in postoperative FS and occlusion attained with CAT and fixed OT after OS?” Indexed databases were searched up to and including October 2023 using different keywords. Original clinical studies that compared postoperative FS and occlusion attained with CAT and fixed OT after OS were included. Risk of bias (RoB) and quality of evidence were also assessed. Four retrospective studies were included. One study reported no difference in postoperative FS among patients that underwent CAT or fixed OT after OS. In one study, patients treated with CAT demonstrated less FS in the first post-surgical week than individuals that underwent fixed OT. In one study, postoperative occlusion was comparable among patients that underwent CAT or fixed OT, whereas in another, postoperative occlusion was better in patients that underwent fixed OT than CAT. All studies had a moderate RoB and none of the investigations were based on power-adjusted data. Based upon the sparsity and questionable quality of available evidence, there is a need to render a firm conclusion. However, it seems that CAT and fixed OT are comparable in relation to postoperative occlusion and FS after OS.
- Published
- 2023
- Full Text
- View/download PDF
17. Haematoma of the buccal space in an edentulous patient – a case report.
- Author
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Maciver, Rory, Ali, Sarah, Mackenzie, Fiona R., and Henderson, Neil
- Subjects
HEMATOMA ,DENTAL pathology ,DENTAL students ,BLOOD testing ,ORAL surgery ,EDENTULOUS mouth - Abstract
Background: Oral swellings can be attributed to various causes, both odontogenic and non‐odontogenic in nature. This paper will discuss a buccal swelling caused by a haematoma. Case presentation: A 76‐year‐old edentulous male patient presented to a dental student outreach clinic with a three‐day history of a right‐sided facial swelling. No dental cause could be confirmed and so the patient was referred to the local secondary oral surgery department. The patient was examined, and an ultrasound of the swelling was arranged on the same day. The swelling was aspirated, and a haematoma was deemed the likely cause. After aspiration and a course of antibiotics, the swelling reduced rapidly. Blood tests were undertaken, and no underlying cause could be identified. Conclusions: Although uncommon, haematoma should be considered within differential diagnoses when dental pathology has been ruled out. A course of antibiotics is indicated where symptoms appear consistent with a systemic infection and timely referral to local dental hospital services is recommended. Blood tests should be requested to identify any undiagnosed coagulopathies or platelet abnormalities and liaison with local haematology services if resolution is not achieved would be appropriate. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
18. Unilateral Facial Swelling in a Sickle Cell Patient.
- Author
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Akhouri R, Fowler A, Schwarz CT, and Patel L
- Abstract
Acute soft head syndrome (ASHS) is a rare complication of sickle cell disease that often requires a high index of suspicion and is often a diagnosis of exclusion. We present the case of an 18-year-old male with sickle cell disease in the United States who developed acute soft head syndrome without known traumatic injury. The goal of this case presentation is to provide awareness and education regarding a rare complication of sickle cell disease and recommended management for the associated symptoms., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Akhouri et al.)
- Published
- 2024
- Full Text
- View/download PDF
19. The effects of Kinesio tapes on facial swelling following bimaxillary orthognathic surgery in the supraclavicular region
- Author
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Golkar, Mohsen, Taheri, Anita, Alam, Mostafa, Asadi, Yasin, and Keyhan, Seied Omid
- Published
- 2023
- Full Text
- View/download PDF
20. Facial chondroid syringoma: A rare and important differential diagnosis
- Author
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Saleh S Elbalka, Amany Hassan, Mohamed Hamdy, and Islam H Metwally
- Subjects
adnexal tumors ,chondroid syringoma ,facial swelling ,mixed skin tumor ,Surgery ,RD1-811 - Abstract
Chondroid syringomas (CSs) are benign adnexal skin tumors usually affecting adolescent females in the periorbital region, and may have calcifications. Malignant transformation is very rarely encountered. There is a tendency to either medical treatment or intralesional injection of these lesions when confirmed benign especially if multiple. We herein describe a female with a periorbital benign CS. The presurgery cytology failed to predict the diagnosis, but surgical excision was attempted with good result. Both pathologists and surgeons are encouraged to add this differential in their diagnostic package of facial subcutaneous swellings.
- Published
- 2022
- Full Text
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21. Development of a Method for Quantitative Evaluation of Facial Swelling in a Rat Model of Cerebral Ischemia by Facial Image Processing
- Author
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Yanfei Liu, Hui Huang, Yiwen Li, Jing Cui, Tiejun Tong, Hongjun Yang, and Yue Liu
- Subjects
ischemic stroke ,occlusion of the middle cerebral artery ,artificial intelligence ,facial swelling ,rat models ,Medicine (General) ,R5-920 - Abstract
A quantitative method for the evaluation of facial swelling in rats with middle cerebral artery occlusion (MCAO) was established using a mathematical method for the first time. The rat model of MCAO was established via bilateral common carotid artery ligation. Three groups of rats with the same baseline were selected (model group, positive drug group, and control group) according to their behavioral score and body weight 24 h after surgery. Drug administration was initiated on post-MCAO day 8 and was continued for 28 days. Mobile phones were used to collect facial images at different time points after surgery. In facial image analysis, the outer canthi of both eyes were used as the facial dividing line, and the outer edge of the rat's face was framed using the marking method, and the framed part was regarded as the facial area (S) of the rats. The histogram created with Photoshop CS5 was used to measure the face area in pixels. The distance between the outer canthi of both eyes (Le) and vertical line from the tip of the nose to the line joining the eyes was recorded as H1, and the line from the tip of the nose to the midpoint of the line joining the eyes was recorded as H2. The facial area was calibrated based on the relationship between H1 and H2. The distance between the eyes was inversely proportional to the distance between the rats and mobile phone such that the face area was calibrated by unifying Le. The size of Le between the eyes was inversely proportional to the distance between the rats and mobile phone. This was used to calibrate the face area. When compared with the control group, the facial area of the model group gradually increased from postoperative day 1 to day 7, and there was a significant difference in the facial area of the model group on postoperative day 7. Hence, positive drugs exhibited the effect of improving facial swelling. H1 and H2 can reflect the state of turning the head and raising the head of the rats, respectively. Facial area was calibrated according to the relationship between H1 and H2, which had no obvious effect on the overall conclusion. Furthermore, mobile phone lens was used to capture the picture of rat face, and the distance between the eyes and H1 and H2 was used to calibrate the facial area. Hence, this method is convenient and can be used to evaluate subjective judgment of the human eyes via a quantitative method.
- Published
- 2022
- Full Text
- View/download PDF
22. Paramassetric Subcutaneous Dirofilariasis: A Rare Entity.
- Author
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Das, Ajay T., Soman, Sooraj, Thomas, Tom, Aslam, Sachin A., Kalathil, Leslie Sara Mathew, and Vijayakumar, Depesh
- Subjects
- *
MOSQUITO vectors , *PERITONEUM , *PARASITIC diseases , *PULMONARY nodules , *MAXILLOFACIAL surgery , *ALPHAVIRUSES , *NEUROCYSTICERCOSIS - Abstract
Dirofilariasis is an uncommon zoonotic parasitic infection affecting humans due to the bite of a mosquito vector. It is an endemic caused by Dirofilaria which is characterized in humans as nodules in lungs, subcutaneous tissue, peritoneal cavity, eyes. We present a case of Dirofilariasis with subcutaneous presentation in paramassetric region. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
23. Massive Pneumomediastinum and Subcutaneous Emphysema Secondary to Foreign Body Aspiration.
- Author
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Gatt, Dvir, Golan-Tripto, Inbal, Goldbart, Aviv, and Aviram, Micha
- Subjects
- *
SUBCUTANEOUS emphysema , *FOREIGN bodies , *MEDICAL personnel , *PNEUMOMEDIASTINUM , *CHILD patients , *OPERATIVE surgery - Abstract
Background: Spontaneous pneumomediastinum (SPM) occurs in cases of mediastinal leaks that are not caused by trauma, mechanical ventilation, or other surgical procedures. In most cases, in the pediatric population a trigger can be identified, most commonly asthma. SPM caused by foreign body aspiration is not a common entity. It is usually a benign condition that generally resolves without severe sequela, but in some cases, severe morbidity and mortality have been documented. Treatment is usually conservative and includes rest, analgesics, and treatment of any underlying pathologies.Case Report: We report a case of a 19-month-old boy who presented to the emergency department with acute facial swelling and wheezing with no history of foreign body aspiration. This misleading presentation led the medical staff in the emergency department to initially treat the patient for anaphylaxis. The diagnosis was made only after imaging modalities demonstrated SPM with a suspected foreign body in the right main stem bronchus. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Providers should consider SPM from an aspirated foreign body in young children with respiratory distress and acute facial swelling, especially when crepitus is present. © 2021 Elsevier Inc. [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
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24. A Rare Case of Fibrous Dysplasia Presenting With Facial Swelling and Craniofacial Deformity in a 13-Year-Old Girl.
- Author
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Dhabalia R, Kashikar SV, Parihar P, and Naseri S
- Abstract
Fibrous dysplasia (FD) is a rare benign skeletal disorder that replaces normal bone with fibrous tissue and immature woven bone. We present a case of a 13-year-old girl with right-sided facial swelling and craniofacial deformity since birth, accompanied by nasal obstruction and difficulty in breathing and swallowing. Computed tomography (CT) imaging revealed an expansile bony lesion with a ground-glass matrix involving multiple craniofacial bones. Histopathological examination confirmed the diagnosis of FD. Management involved regular monitoring and conservative measures, with surgical intervention reserved for symptomatic progression or cosmetic concerns. This case underscores the importance of considering FD in the differential diagnosis of craniofacial asymmetry and highlights the collaborative approach to patient care. Further research is needed to optimize management strategies and outcomes for pediatric patients with FD., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Dhabalia et al.)
- Published
- 2024
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25. Facial chondroid syringoma: A rare and important differential diagnosis.
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Elbalka, Saleh, Hassan, Amany, Hamdy, Mohamed, and Metwally, Islam
- Abstract
Chondroid syringomas (CSs) are benign adnexal skin tumors usually affecting adolescent females in the periorbital region, and may have calcifications. Malignant transformation is very rarely encountered. There is a tendency to either medical treatment or intralesional injection of these lesions when confirmed benign especially if multiple. We herein describe a female with a periorbital benign CS. The presurgery cytology failed to predict the diagnosis, but surgical excision was attempted with good result. Both pathologists and surgeons are encouraged to add this differential in their diagnostic package of facial subcutaneous swellings. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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26. Role of mycology in accurate diagnosis of various fungal aetiologies in rhino/orbital diseases: 'needle in a haystack'
- Author
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Surya Ravichandran, Sivaraman Ganesan, Saranya Thangavel, and Rakesh Singh
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Facial swelling ,genetic structures ,Images In… ,business.industry ,Otolaryngology/ENT ,General Medicine ,Mycology ,030105 genetics & heredity ,Nose ,Surgery ,Causality ,03 medical and health sciences ,Left eye ,Endoscopic sinus surgery ,0302 clinical medicine ,Orbital Diseases ,Medicine ,Humans ,Pharynx ,business ,030217 neurology & neurosurgery ,Nasal surgery - Abstract
A 37-year-old man with no known comorbidities presented to our department with complaints of left eye proptosis and diminution of vision for 1 month and left facial swelling for the past 2 years. He underwent left-sided nasal surgery thrice—functional endoscopic sinus surgery (FESS) in 2018
- Published
- 2023
27. Facial Swelling and Pancytopenia: First Features and Clues to the Etiology of Acute Kidney Injury
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Shannon L. Walker, Caroline F. Plott, Michael R. Goetsch, Allan C. Gelber, Charles F. S. Locke, Derek M. Fine, Lois J. Arend, and John A. Woller
- Subjects
Pathology ,medicine.medical_specialty ,Facial swelling ,Pancytopenia ,business.industry ,Acute kidney injury ,General Medicine ,Middle Aged ,Urinalysis ,Kidney Function Tests ,medicine.disease ,Lupus Nephritis ,Diagnosis, Differential ,Face ,Weight Loss ,medicine ,Etiology ,Edema ,Humans ,Drug Therapy, Combination ,Female ,business ,Oral Ulcer ,Fatigue - Published
- 2021
28. Bilateral facial swelling and Facial nerve palsy
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Rahul Pankhania and David Walker
- Subjects
Inflammation ,Male ,Vasculitis ,medicine.medical_specialty ,Facial swelling ,Palsy ,business.industry ,General Medicine ,Emergency department ,Middle Aged ,Critical Care and Intensive Care Medicine ,medicine.disease ,Surgery ,stomatognathic diseases ,Face ,Emergency Medicine ,medicine ,Humans ,Facial nerve palsy ,Facial Nerve Diseases ,Presentation (obstetrics) ,business ,Stroke ,Sudden onset - Abstract
A 53-year-old man presented to the accident and emergency department with sudden onset left-sided facial nerve palsy and a 4-day history of progressive bilateral facial swelling. There is no history of any previous medical conditions, trauma or recent travel. What is the most likely Diagnosis seen in figures 1 and 2? 1. Bell’s Palsy. 2. Stroke. 3. Vasculitis. 4. Parotid abscess. For question see page 02 Figure 1 Patient presentation with bilateral facial swellings and facial nerve palsy. Figure 2 Clinical findings when …
- Published
- 2021
29. Patient with Chronic Liver Disease Was Referred for Evaluation of Oral Infection and Facial Swelling and Needs Multiple Dental Extractions.
- Author
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AlMuzaini AA
- Subjects
- Humans, Tooth Extraction, Mouth Diseases, Liver Diseases complications
- Abstract
When a patient with chronic liver disease due to a hepatitis C virus infection presents with a dental emergency, it is important to identify whether the patient is under good medical management, if severe liver dysfunction exists, or if the patient is with active hepatitis. If records are not available, contacting the patient's physician to obtain the necessary information is prudent. If the source of infection is odontogenic, extraction should not be delayed. Patients with stable chronic liver disease can safely undergo dental extractions with some modifications to the dental treatment plan., (Copyright © 2023 Elsevier Inc. All rights reserved.)
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- 2023
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30. Haematoma of the buccal space in an edentulous patient - a case report
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Fiona R. Mackenzie, Rory Maciver, Neil Henderson, and Sarah Ali
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Facial swelling ,medicine.medical_specialty ,Referral ,business.industry ,General surgery ,030206 dentistry ,Buccal administration ,Case presentation ,Oral surgery department ,Odontogenic ,03 medical and health sciences ,stomatognathic diseases ,0302 clinical medicine ,Medicine ,Surgery ,Oral Surgery ,Buccal space ,business ,Edentulous patient ,030217 neurology & neurosurgery - Abstract
Background:\ud \ud Oral swellings can be attributed to various causes, both odontogenic and non‐odontogenic in nature. This paper will discuss a buccal swelling caused by a haematoma.\ud \ud Case presentation:\ud \ud A 76‐year‐old edentulous male patient presented to a dental student outreach clinic with a three‐day history of a right‐sided facial swelling. No dental cause could be confirmed and so the patient was referred to the local secondary oral surgery department. The patient was examined, and an ultrasound of the swelling was arranged on the same day. The swelling was aspirated, and a haematoma was deemed the likely cause. After aspiration and a course of antibiotics, the swelling reduced rapidly. Blood tests were undertaken, and no underlying cause could be identified.\ud \ud Conclusions:\ud \ud Although uncommon, haematoma should be considered within differential diagnoses when dental pathology has been ruled out. A course of antibiotics is indicated where symptoms appear consistent with a systemic infection and timely referral to local dental hospital services is recommended. Blood tests should be requested to identify any undiagnosed coagulopathies or platelet abnormalities and liaison with local haematology services if resolution is not achieved would be appropriate.
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- 2022
31. Intraparotid facial varix
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Regis Hila, Gregg S. Landis, Jeffrey Silpe, and Yana Etkin
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medicine.medical_specialty ,Facial swelling ,RD1-811 ,Venous disease ,Palpation ,Case report ,Varicose veins ,medicine ,Diseases of the circulatory (Cardiovascular) system ,Facial mass ,Varix ,medicine.diagnostic_test ,business.industry ,Parotidectomy ,Normal limit ,Parotid gland ,stomatognathic diseases ,medicine.anatomical_structure ,RC666-701 ,Surgery ,Physical exam ,Radiology ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business - Abstract
A 72-year-old man had presented with a 4-day history of progressive left-sided facial swelling associated with pain. The physical examination revealed left facial fullness over the parotid gland without tenderness to palpation. His vital signs and laboratory test findings were within normal limits. A computed tomography scan demonstrated a left facial varix measuring 3.4 cm × 2.8 cm within an unremarkable-appearing parotid gland. Parotidectomy vs close observation were discussed, and the patient decided to pursue nonoperative management. Ultimately, his symptoms were self-limited, and the swelling had resolved within 6 months after the diagnosis. Interval computed tomography demonstrated a thrombosed left facial varix measuring 1.3 cm × 1.1 cm.
- Published
- 2022
32. Radiographic and CT features of zygomatic arch pneumatization in a Thoroughbred with a recurrent progressive ethmoid hematoma
- Author
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Marius Conradie, Ann Carstens, and Mickael Patrice Robert
- Subjects
Male ,Hematoma ,Zygoma ,Facial swelling ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Radiography ,Computed tomography ,Anatomy ,Maxillary Sinus ,Ethmoid hematoma ,medicine.anatomical_structure ,Cortex (anatomy) ,Biopsy ,Paranasal Sinus Diseases ,otorhinolaryngologic diseases ,medicine ,Animals ,Horse Diseases ,Zygomatic arch ,Horses ,Tomography, X-Ray Computed ,business ,Sinus (anatomy) - Abstract
A 7-year-old Thoroughbred gelding presented with a history of mild unilateral right-sided epistaxis and facial swelling over the right caudal maxillary sinus and zygomatic arch. Eleven months previously a progressive ethmoid hematoma had been surgically removed from the right caudal maxillary and conchofrontal sinus. Computed tomography identified a large expansile soft-tissue attenuating mass in the right caudal maxillary sinus, with protrusion into the conchofrontal sinus, that extended into the zygomatic arch. Lytic expansion and thinning of the cortex with pneumatization of the zygomatic arch was present. The mass was surgically excised after a biopsy had confirmed the recurring progressive ethmoid hematoma.
- Published
- 2021
33. Effect of pre-operative 40 mg oral methylprednisolone on post- odontectomy facial swelling, intraoral redness, pain and level of TNF-α
- Author
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Yusa, Harpindo, Hasan, Cahya Yustisia, and Dwirahardjo, Bambang
- Subjects
facial swelling ,intraoral redness ,level of TNF-ɑ ,methylprednisolone ,pain ,pre-odontectomy ,dentistry - Abstract
Odontectomy is the surgical removal of teeth by making a mucoperiosteal flap and reducing the jawbone. This procedure is likely to cause injury and damage to soft and hard tissues, stimulate inflammatory responses, and generate release of proinflammatory cytokines, one of which is TNF- ɑ, resulting in the facial swelling, intraoral redness, and pain. This study was aimed at observing effects of 40 mg methylprednisolone, administered 1 hour before odontectomy on facial swelling, intraoral redness, and pain and level of TNF-ɑ after odontectomy. The randomized placebo-control trial study involved 24 subjects who underwent odontectomy at the Oral Surgery and Maxillofacial clinic of Prof. Soedomo Dental Hospital, Universitas Gadjah Mada. To comply with the inclusion criteria, the subjects were divided into placebo group (12 patients) and methylprednisolone group (12 patients). The observation of facial swelling, intraoral redness, pain (VAS) and level of TNF-ɑ (ELISA) was done before odontectormy, H+1 (24 hours after odontectomy) and H+3 (72 hours after odontectomy). The data gathered were analyzed using Repeated Measures ANOVA and post-hoc Bonferroni (p < 0.05). The results showed that those administered with methylprednisolone an hour before odontectomy experienced less postoperative facial swelling (p = 0.000), a lower score of intraoral redness (p = 0.000), a lower score of pain (p = 0.000) and a lower level of TNF-ɑ (p = 0.000) compared to the placebo. The changes in TNF-α showed the strongest correlation with the changes in postoperative pain and intraoral redness compared with facial swelling. Oral administration of 40 mg methylprednisolone an hour before odontectomy is more effective in reducing facial swelling, intraoral redness, pain and level of TNF-ɑ following odontectomy of mandibular third molar compared with the placebo.
- Published
- 2022
34. Standing excision of a paranasal osteoma in a 3‐year‐old Standardbred gelding
- Author
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N. E. Lean, Benjamin J. Ahern, Mark McGarry, and Pippa E. Henderson
- Subjects
Cosmetic appearance ,Facial swelling ,medicine.medical_specialty ,Bone flap ,General Veterinary ,business.industry ,medicine.disease ,Surgery ,body regions ,Nasal discharge ,Paranasal sinuses ,medicine.anatomical_structure ,Medicine ,General anaesthesia ,Surgical excision ,business ,Osteoma - Abstract
Osteomas are an uncommon benign neoplasia in horses, which most frequently affect the paranasal sinuses. There are only 25 reported cases in the literature. Clinical signs typically associated with paranasal osteoma formation include nasal discharge, ocular and/or facial swelling and distortion. Historically, surgical excision under general anaesthesia has been the standard approach for the treatment of large osteomas with standing surgery reserved for small masses. This case report describes standing removal of an extensive paranasal osteoma through a maxillary bone flap, without recurrence. Long-term follow up at 2 years confirmed a good cosmetic appearance and successful return to racing.
- Published
- 2021
35. Pathology Mimicking Orofacial Pain.
- Author
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Sandhu S and Handa S
- Subjects
- Female, Humans, Middle Aged, Biopsy, Fine-Needle, Facial Pain diagnosis, Facial Pain etiology, Diagnosis, Differential, Adenoma, Pleomorphic diagnosis, Adenoma, Pleomorphic pathology, Adenoma, Pleomorphic therapy, Parotid Neoplasms diagnosis, Parotid Neoplasms pathology, Parotid Neoplasms therapy
- Abstract
A case of a 64-year-old woman is reported, who developed new-onset pain over a preexisting area of right mandibular fullness. Clinical examination, MRI, and fine-needle aspiration cytology confirmed the diagnosis of a benign parotid gland tumor-pleomorphic adenoma, which was treated by total parotidectomy with complete removal of the tumor. When evaluating a patient with orofacial pain, oral health care providers should be cognizant of all potential differential diagnoses, especially in the setting of red flags such as persistent or enlarging facial swelling/fullness., Competing Interests: Disclosure The authors do not have any disclosures. The authors do not have any conflicts of interest associated with this publication, and there has been no financial support for this work that could have influenced its outcome. This manuscript is original, has not been previously published, and is not currently under consideration by another journal., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2023
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- View/download PDF
36. Paediatric paranasal sinus fibrous dysplasia.
- Author
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Adeyemo AA, Ogunkeyede SA, Daniel A, and Lasisi AO
- Subjects
- Humans, Child, Adolescent, Retrospective Studies, Recurrence, Hospitals
- Abstract
Fibrous dysplasia in the bony walls of a paranasal sinus is a developmental tumour that is associated with a marked facial deformity. Delay in hospital presentation contributes to the destructive resection techniques employed and the management outcome. Our study looks at the factors for delay in hospital presentation and the management outcome by a retrospective review between January 1997 and December 2018. Of 43 children (M: F 1:1.2) with a mean age of 12 ± 1.75 years, the maxillary bones were mostly affected. All underwent surgical resection with good management outcomes except for maxillectomy. Tumour recurrence was noted in five and there was no mitotic cell at histology. The clinical symptoms of fibrous dysplasia vary in severity and age of onset, often with late hospital presentation already with complications. Health education is needed to reverse this trend.
- Published
- 2023
- Full Text
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37. Orbital Apex Syndrome Secondary to SMARCB1-Deficient Invasive Sinonasal Carcinoma.
- Author
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Massey D and Saab M
- Abstract
Orbital apex syndrome (OAS) is a clinical entity defined by ophthalmoplegia and optic nerve dysfunction due to local disruption of the orbital apex. The causes of OAS are extensive and include infectious, inflammatory, traumatic, iatrogenic, and neoplastic conditions. Thus, appropriate management is dependent on an accurate and timely diagnosis of the underlying etiology. We present a case of a 58-year-old female who presented to the emergency department with ophthalmoplegia of subacute onset and diminished visual acuity in the setting of two weeks of headache, ocular pain, and facial swelling. She was ultimately diagnosed with OAS and admitted to the hospital for five days for further evaluation. She was found to have an incurable primary SMARCB1-deficient sinonasal carcinoma with an invasion of her orbital apex. A multidisciplinary management approach involving chemotherapy, radiation, and surgical intervention was performed, and the patient responded well. Nearly two years after her diagnosis, she continues to have stable residual carcinoma without evidence of recurrence or metastatic disease. Her visual acuity has returned to normal limits, and her oculomotor function has returned to near-normal levels., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2022, Massey et al.)
- Published
- 2022
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- View/download PDF
38. A case of giant ameloblastoma: destructive effect on the facial skeleton and soft tissues of the head and neck
- Author
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Branislav Borza, Květuše Lovásová, Milan Almaši, David Kachlik, Ingrid Hodorová, and Peter Kizek
- Subjects
Medicine (General) ,Facial swelling ,facial skeleton ,tissue destruction ,Case Reports ,Biochemistry ,Ameloblastoma ,mandible ,R5-920 ,Humans ,Medicine ,hemimandibulectomy ,Head and neck ,business.industry ,Biochemistry (medical) ,Mandible ,Soft tissue ,computed tomography ,Cell Biology ,General Medicine ,Anatomy ,medicine.disease ,Slow growth ,medicine.anatomical_structure ,Hemimandibulectomy ,Facial skeleton ,Female ,Tomography, X-Ray Computed ,business ,Head ,Neck - Abstract
Ameloblastoma is a benign odontogenic tumor characterized by slow growth causing painless facial swelling. The tumor can behave locally aggressively, and may have direct destructive effects on the surrounding soft and hard tissues. This paper reports the unique case of a female patient with giant ameloblastoma of the mandible. Computed tomography (CT) revealed an enormous swelling of the left side of the face, resorption of the affected hemi-mandible, left maxilla, and tissues of the temporal, infratemporal, and pterygopalatine fossae. Pressure from the tumor resulted in displacement and destruction of the facial skeleton, upper aero-digestive tract structures, and some structures of the neck. The patient was treated by radical hemimandibulectomy with removal of the tumorous mass. Precise knowledge of the anatomical structures, and their locations and topographical relationships is required in the diagnosis and treatment plan for each surgical procedure in cases of giant ameloblastoma. CT imaging can be used to determine the extent and exact location of the lesion, revealing other important details that may help in selecting appropriate treatment.
- Published
- 2021
39. Development of a Method for Quantitative Evaluation of Facial Swelling in a Rat Model of Cerebral Ischemia by Facial Image Processing.
- Author
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Liu Y, Huang H, Li Y, Cui J, Tong T, Yang H, and Liu Y
- Abstract
A quantitative method for the evaluation of facial swelling in rats with middle cerebral artery occlusion (MCAO) was established using a mathematical method for the first time. The rat model of MCAO was established via bilateral common carotid artery ligation. Three groups of rats with the same baseline were selected (model group, positive drug group, and control group) according to their behavioral score and body weight 24 h after surgery. Drug administration was initiated on post-MCAO day 8 and was continued for 28 days. Mobile phones were used to collect facial images at different time points after surgery. In facial image analysis, the outer canthi of both eyes were used as the facial dividing line, and the outer edge of the rat's face was framed using the marking method, and the framed part was regarded as the facial area (S) of the rats. The histogram created with Photoshop CS5 was used to measure the face area in pixels. The distance between the outer canthi of both eyes (Le) and vertical line from the tip of the nose to the line joining the eyes was recorded as H1, and the line from the tip of the nose to the midpoint of the line joining the eyes was recorded as H2. The facial area was calibrated based on the relationship between H1 and H2. The distance between the eyes was inversely proportional to the distance between the rats and mobile phone such that the face area was calibrated by unifying Le. The size of Le between the eyes was inversely proportional to the distance between the rats and mobile phone. This was used to calibrate the face area. When compared with the control group, the facial area of the model group gradually increased from postoperative day 1 to day 7, and there was a significant difference in the facial area of the model group on postoperative day 7. Hence, positive drugs exhibited the effect of improving facial swelling. H1 and H2 can reflect the state of turning the head and raising the head of the rats, respectively. Facial area was calibrated according to the relationship between H1 and H2, which had no obvious effect on the overall conclusion. Furthermore, mobile phone lens was used to capture the picture of rat face, and the distance between the eyes and H1 and H2 was used to calibrate the facial area. Hence, this method is convenient and can be used to evaluate subjective judgment of the human eyes via a quantitative method., Competing Interests: HH was employed by the company Beijing Duan-Dian Pharmaceutical Research & Development Co., Ltd., Beijing, China. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Liu, Huang, Li, Cui, Tong, Yang and Liu.)
- Published
- 2022
- Full Text
- View/download PDF
40. Facial Natural Killer/T-Cell Lymphoma: A Deadly Sinusitis Mimic.
- Author
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Bridwell RE, Gillis SC, Davis GW, Inman BL, and Long B
- Abstract
Sinusitis and pre-septal cellulitis are common emergency department (ED) conditions, though rare and lethal mimics can present in a similar manner. We present a case of natural killer (NK)/T-cell lymphoma mimicking sinusitis and pre-septal cellulitis. Diagnosis of this condition may include imaging modalities such as CT and MRI, though definitive diagnosis requires tissue biopsy. Therapeutic interventions involve chemotherapy and radiation, with little role for surgical debridement. Complications in treatment can occur including hemophagocytic lymphohistiocytosis. Despite standard treatments, mortality remains high for cases of facial lymphoma., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2022, Bridwell et al.)
- Published
- 2022
- Full Text
- View/download PDF
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