11 results on '"Faye, Joseph"'
Search Results
2. One hundred malaria attacks since birth. A longitudinal study of African children and young adults exposed to high malaria transmission
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Trape, Jean-François, Diagne, Nafissatou, Diene-Sarr, Fatoumata, Faye, Joseph, Dieye-Ba, Fambaye, Bassène, Hubert, Badiane, Abdoulaye, Bouganali, Charles, Tall, Adama, Ndiaye, Ramatoulaye, Doucouré, Souleymane, Wotodjo, Amélé Nyedzie, Vigan-Womas, Inès, Guillotte-Blisnick, Micheline, Talla, Cheikh, Niang, Makhtar, Touré-Baldé, Aissatou, Perraut, Ronald, Roussilhon, Christian, Druilhe, Pierre, Rogier, Christophe, Mercereau-Puijalon, Odile, Loucoubar, Cheikh, and Sokhna, Cheikh
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- 2024
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3. Study of the Biological Quality of the Water in the Manantali Dam Reservoir: Analysis of the Fish Fauna and Plankton Communities
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Faye, Joseph Mbeur, primary, Ndao, Saïdou, additional, and Sambou, Louis Eugène Victor, additional
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- 2024
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4. Analysis of contact tracing data showed contribution of asymptomatic and non-severe infections to the maintenance of SARS-CoV-2 transmission in Senegal
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Diarra, Maryam, primary, Ndiaye, Ramatoulaye, additional, Barry, Aliou, additional, Talla, Cheikh, additional, Diagne, Moussa Moise, additional, Dia, Ndongo, additional, Faye, Joseph, additional, Sarr, Fatoumata Diene, additional, Gaye, Aboubacry, additional, Diallo, Amadou, additional, Cisse, Mamadou, additional, Dieng, Idrissa, additional, Fall, Gamou, additional, Tall, Adama, additional, Faye, Oumar, additional, Faye, Ousmane, additional, Sall, Amadou A., additional, and Loucoubar, Cheikh, additional
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- 2023
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5. Evolution of the Physico-Chemical Quality of the Water in the Manantali Dam Reservoir from 1989 (One Year after Impoundment) to 2022
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Faye, Joseph Mbeur, primary, Ndao, Saïdou, additional, and Sambou, Louis Eugène Victor, additional
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- 2023
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6. Correction to: Fine-scale Spatiotemporal Mapping of Asymptomatic and Clinical Plasmodium falciparum Infections: Epidemiological Evidence for Targeted Malaria Elimination Interventions
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Niang, Makhtar, primary, Sandfort, Mirco, additional, Mbodj, Adja Fatou, additional, Diouf, Babacar, additional, Talla, Cheikh, additional, Faye, Joseph, additional, Sane, Rokhaya, additional, Thiam, Laty Gaye, additional, Thiam, Alassane, additional, Badiane, Abdoulaye, additional, Vigan-Womas, Ines, additional, Diagne, Nafissatou, additional, Diene Sarr, Fatoumata, additional, Mueller, Ivo, additional, Sokhna, Cheikh, additional, White, Michael, additional, and Toure-Balde, Aissatou, additional
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- 2022
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7. Non-pharmaceutical interventions and COVID-19 vaccination strategies in Senegal: a modelling study
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Diarra, Maryam, Kebir, Amira, Talla, Cheikh, Barry, Aliou, Faye, Joseph, Louati, Dorra, Opatowski, Lulla, Diop, Mamadou, Consortium, Repair, White, Lisa, Loucoubar, Cheikh, Miled, Slimane Ben, Institut Pasteur de Dakar, Réseau International des Instituts Pasteur (RIIP), Institut Pasteur de Tunis, Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials (EMAE), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), University of Oxford, This study was funded (or cofunded) by the French Ministry for Europe and Foreign Affairs via the project ‘REPAIR Covid-19-Africa’, coordinated by the Pasteur International Network association., REPAIR Consortium: Mohamed Hamidouche (Departement of Production and Development of Viral Vaccines, Institut Pasteur d'Algérie, Alger, Algeria), Ramatoulaye Hamidou Lazoumar (Epidemiologie Santé-Environnement-Climat, Centre de Recherche Médicale Sanitaire, Niamey, Niger), Jules Brice Tchatchueng (Service d'épidémiologie et de santé publique, Centre Pasteur du Cameroun, Yaounde, Centar, Cameroon), Walid Ben Aribi (Bio-Informatics, Mathematics, Statistics, Institut Pasteur de Tunis, Tunis, Tunisia), Nesrine Ben Yahia (National School of Computer Sciences, University of Manouba, Manouba, Tunisia), Ahmed Nasri (Bio-Informatics, Mathematics, Statistics, Institut Pasteur de Tunis, Tunis, Tunisia, and National School of Computer Sciences, University of Manouba, Manouba, Tunisia), Bechir Naffeti (Bio-Informatics, Mathematics, Statistics, Institut Pasteur de Tunis, Tunis, Tunisia), Arsene Brunelle Sandie (Service d'épidémiologie et de santé publique, Centre Pasteur du Cameroun, Yaounde, Centar, Cameroon).
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Adult ,MESH: Pandemics ,COVID-19 Vaccines ,Adolescent ,[SDV]Life Sciences [q-bio] ,prevention strategies ,control strategies ,Young Adult ,MESH: Senegal ,MESH: Child ,MESH: COVID-19 ,Humans ,MESH: SARS-CoV-2 ,mathematical modelling ,Child ,Pandemics ,Aged ,MESH: Adolescent ,MESH: Aged ,MESH: Humans ,MESH: Middle Aged ,SARS-CoV-2 ,Health Policy ,MESH: Child, Preschool ,Vaccination ,Public Health, Environmental and Occupational Health ,COVID-19 ,MESH: Adult ,MESH: Vaccination ,vaccines ,Middle Aged ,Senegal ,MESH: Young Adult ,MESH: COVID-19 Vaccines ,Child, Preschool - Abstract
BackgroundWhen vaccines against the novel COVID-19 were available in Senegal, many questions were raised. How long should non-pharmaceutical interventions (NPIs) be maintained during vaccination roll-out? What are the best vaccination strategies?MethodsIn this study, we used an age-structured dynamic mathematical model. This model uses parameters based on SARS-CoV-2 virus, information on different types of NPIs, epidemiological and demographic data, some parameters relating to hospitalisations and vaccination in Senegal.ResultsIn all scenarios explored, the model predicts a larger third epidemic wave of COVID-19 in terms of new cases and deaths than the previous waves. In a context of limited vaccine supply, vaccination alone will not be sufficient to control the epidemic, and the continuation of NPIs is necessary to flatten the epidemic curve. Assuming 20% of the population have been vaccinated, the optimal period to relax NPIs would be a few days from the last peak. Regarding the prioritisation of age groups to be vaccinated, the model shows that it is better to vaccinate individuals aged 5–60 years and not just the elderly (over 60 years) and those in high-risk groups. This strategy could be more cost-effective for the government, as it would reduce the high costs associated with hospitalisation. In terms of vaccine distribution, the optimal strategy would be to allocate full dose to the elderly. If vaccine doses are limited, half dose followed by full dose would be sufficient for people under 40 years because whether they receive half or full dose, the reduction in hospitalisations would be similar and their death-to-case ratio is very low.ConclusionsThis study could be presented as a decision support tool to help devise strategies to control the COVID-19 pandemic and help the Ministry of Health to better manage and allocate the available vaccine doses.
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- 2021
8. Fine-scale Spatiotemporal Mapping of Asymptomatic and Clinical Plasmodium falciparum Infections: Epidemiological Evidence for Targeted Malaria Elimination Interventions.
- Author
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Niang, Makhtar, Sandfort, Mirco, Mbodj, Adja Fatou, Diouf, Babacar, Talla, Cheikh, Faye, Joseph, Sane, Rokhaya, Thiam, Laty Gaye, Thiam, Alassane, Badiane, Abdoulaye, Vigan-Womas, Ines, Diagne, Nafissatou, Sarr, Fatoumata Diene, Mueller, Ivo, Sokhna, Cheikh, White, Michael, and Toure-Balde, Aissatou
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PROTOZOA ,BLOOD ,MALARIA ,CARRIER state (Communicable diseases) ,DISEASE management - Abstract
Background A detailed understanding of the contribution of the asymptomatic Plasmodium reservoir to the occurrence of clinical malaria at individual and community levels is needed to guide effective elimination interventions. This study investigated the relationship between asymptomatic Plasmodium falciparum carriage and subsequent clinical malaria episodes in the Dielmo and Ndiop villages in Senegal. Methods The study used a total of 2792 venous and capillary blood samples obtained from asymptomatic individuals and clinical malaria datasets collected from 2013 to 2016. Mapping, spatial clustering of infections, and risk analysis were performed using georeferenced households. Results High incidences of clinical malaria episodes were observed to occur predominantly in households of asymptomatic P falciparum carriers. A statistically significant association was found between asymptomatic carriage in a household and subsequent episode of clinical malaria occurring in that household for each individual year (P values were 0.0017, 6 × 10
–5 , 0.005, and 0.008 for the years 2013, 2014, 2015, and 2016 respectively) and the combined years (P = 8.5 × 10–8 ), which was not found at the individual level. In both villages, no significant patterns of spatial clustering of P falciparum clinical cases were found, but there was a higher risk of clinical episodes <25 m from asymptomatic individuals in Ndiop attributable to clustering within households. Conclusion The findings provide strong epidemiological evidence linking the asymptomatic P falciparum reservoir to clinical malaria episodes at household scale in Dielmo and Ndiop villagers. This argues for a likely success of a mass testing and treatment intervention to move towards the elimination of malaria in the villages of Dielmo and Ndiop. [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
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9. One hundred malaria attacks since birth. A longitudinal study of African children and young adults exposed to high malaria transmission.
- Author
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Trape JF, Diagne N, Diene-Sarr F, Faye J, Dieye-Ba F, Bassène H, Badiane A, Bouganali C, Tall A, Ndiaye R, Doucouré S, Wotodjo AN, Vigan-Womas I, Guillotte-Blisnick M, Talla C, Niang M, Touré-Baldé A, Perraut R, Roussilhon C, Druilhe P, Rogier C, Mercereau-Puijalon O, Loucoubar C, and Sokhna C
- Abstract
Background: Despite significant progress in malaria control over the past twenty years, malaria remains a leading cause of child morbidity and mortality in Tropical Africa. As most patients do not consult any health facility much uncertainty persists about the true burden of the disease and the range of individual differences in susceptibility to malaria., Methods: Over a 25-years period, from 1990 to 2015, the inhabitants of Dielmo village, Senegal, an area of intense malaria transmission, have been monitored daily for their presence in the village and the occurrence of diseases. In case of fever thick blood films were systematically examined through microscopy for malaria parasites and patients received prompt diagnosis and treatment., Findings: We analysed data collected in 111 children and young adults monitored for at least 10 years (mean 17.3 years, maximum 25 years) enrolled either at birth (95 persons) or during the two first years of life. A total of 11,599 episodes of fever were documented, including 5268 malaria attacks. The maximum number of malaria attacks in a single person was 112. Three other persons suffered one hundred or more malaria attacks during follow-up. The minimum number of malaria attacks in a single person was 11. The mean numbers of malaria attacks in children reaching their 4th, 7th, and 10th birthdays were 23.0, 37.7, and 43.6 attacks since birth, respectively. Sixteen children (14.4%) suffered ten or more malaria attacks each year at ages 1-3 years, and six children (5.4%) each year at age 4-6 years., Interpretation: Long-term close monitoring shows that in highly endemic areas the malaria burden is higher than expected. Susceptibility to the disease may vary up to 10-fold, and for most children childhood is an endless history of malaria fever episodes. No other parasitic, bacterial or viral infection in human populations has such an impact on health., Funding: The Pasteur Institutes of Dakar and Paris, the Institut de Recherche pour le Développement, and the French Ministry of Cooperation provided funding., Competing Interests: We declare that we have no conflict of interest., (© 2023 The Author(s).)
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- 2023
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10. First wave COVID-19 pandemic in Senegal: Epidemiological and clinical characteristics.
- Author
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Diarra M, Barry A, Dia N, Diop M, Sonko I, Sagne S, Sarr FD, Talla C, Tall A, Faye J, Diop B, Diagne CT, Gaye A, Diallo A, Mbaye R, Cisse M, Taieb F, Faye O, Lakhe NA, Papa Samba B, Diallo K, Fall NM, Badiane AS, Fortes L, Diop M, Thioub D, Ly AB, Faye O, Seydi M, Bousso A, Sall AA, and Loucoubar C
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- Adolescent, Aged, Humans, Pandemics, SARS-CoV-2, Senegal epidemiology, COVID-19 epidemiology, Cardiovascular Diseases, Diabetes Mellitus epidemiology, Hypertension epidemiology
- Abstract
Background: The novel coronavirus disease 2019 (COVID-19) pandemic has spread from China to the rest of the world. Africa seems less impacted with lower number of cases and deaths than other continents. Senegal recorded its first case on March 2, 2020. We present here data collected from March 2 to October 31, 2020 in Senegal., Methods: Socio-demographic, epidemiological, clinical and virological information were collected on suspected cases. To determine factors associated with diagnosed infection, symptomatic disease and death, multivariable binary logistic regression and log binomial models were used. Epidemiological parameters such as the reproduction number and growth rate were estimated., Results: 67,608 suspected cases were tested by the IPD laboratories (13,031 positive and 54,577 negative). All age categories were associated with SARS-CoV-2 infection, but also patients having diabetes or hypertension or other cardiovascular diseases. With diagnosed infection, patients over 65 years and those with hypertension and cardiovascular disease and diabetes were highly associated with death. Patients with co-morbidities were associated with symptomatic disease, but only the under 15 years were not associated with. Among infected, 27.67% were asymptomatic (40.9% when contacts were systematically tested; 12.11% when only symptomatic or high-risk contacts were tested). Less than 15 years-old were mostly asymptomatic (63.2%). Dakar accounted for 81.4% of confirmed cases. The estimated mean serial interval was 5.57 (± 5.14) days. The average reproduction number was estimated at 1.161 (95%CI: 1.159-1.162), the growth rate was 0.031 (95%CI: 0.028-0.034) per day., Conclusions: Our findings indicated that factors associated with symptomatic COVID-19 and death are advanced age (over 65 years-old) and comorbidities such as diabetes and hypertension and cardiovascular disease., Competing Interests: The authors have declared that no competing interests exist.
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- 2022
- Full Text
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11. Non-pharmaceutical interventions and COVID-19 vaccination strategies in Senegal: a modelling study.
- Author
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Diarra M, Kebir A, Talla C, Barry A, Faye J, Louati D, Opatowski L, Diop M, White LJ, Loucoubar C, and Miled SB
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Humans, Middle Aged, Pandemics, SARS-CoV-2, Senegal epidemiology, Vaccination, Young Adult, COVID-19, COVID-19 Vaccines
- Abstract
Background: When vaccines against the novel COVID-19 were available in Senegal, many questions were raised. How long should non-pharmaceutical interventions (NPIs) be maintained during vaccination roll-out? What are the best vaccination strategies?, Methods: In this study, we used an age-structured dynamic mathematical model. This model uses parameters based on SARS-CoV-2 virus, information on different types of NPIs, epidemiological and demographic data, some parameters relating to hospitalisations and vaccination in Senegal., Results: In all scenarios explored, the model predicts a larger third epidemic wave of COVID-19 in terms of new cases and deaths than the previous waves. In a context of limited vaccine supply, vaccination alone will not be sufficient to control the epidemic, and the continuation of NPIs is necessary to flatten the epidemic curve. Assuming 20% of the population have been vaccinated, the optimal period to relax NPIs would be a few days from the last peak. Regarding the prioritisation of age groups to be vaccinated, the model shows that it is better to vaccinate individuals aged 5-60 years and not just the elderly (over 60 years) and those in high-risk groups. This strategy could be more cost-effective for the government, as it would reduce the high costs associated with hospitalisation. In terms of vaccine distribution, the optimal strategy would be to allocate full dose to the elderly. If vaccine doses are limited, half dose followed by full dose would be sufficient for people under 40 years because whether they receive half or full dose, the reduction in hospitalisations would be similar and their death-to-case ratio is very low., Conclusions: This study could be presented as a decision support tool to help devise strategies to control the COVID-19 pandemic and help the Ministry of Health to better manage and allocate the available vaccine doses., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2022
- Full Text
- View/download PDF
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