1. Ultra-High-Resolution CT to Detect Intracochlear New Bone Formation after Cochlear Implantation
- Author
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Floris Heutink, Tim M. Klabbers, Wendy J. Huinck, Federica Lucev, Willem Jan van der Woude, Emmanuel A. M. Mylanus, and Berit M. Verbist
- Subjects
Male ,Hearing Tests ,Temporal Bone ,Middle Aged ,Cochlear Implantation ,Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12] ,Cross-Sectional Studies ,All institutes and research themes of the Radboud University Medical Center ,Osteogenesis ,Humans ,Female ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,Tomography, X-Ray Computed ,Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] - Abstract
Background Histopathologic studies reported that cochlear implantation, a well-established means to treat severe-to-profound sensorineural hearing loss, may induce inflammation, fibrosis, and new bone formation (NBF) with possible impact on loss of residual hearing and hearing outcome. Purpose To assess NBF in vivo after cochlear implantation with ultra-high-spatial-resolution (UHSR) CT and its implication on long-term residual hearing outcome. Materials and Methods In a secondary analysis of a prospective single-center cross-sectional study, conducted between December 2016 and January 2018, patients with at least 1 year of cochlear implantation experience underwent temporal bone UHSR CT and residual hearing assessment. Two observers evaluated the presence and location of NBF independently, and tetrachoric correlations were used to assess interobserver reliability. In addition, the scalar location of each electrode was assessed. After consensus agreement, participants were classified into two groups: those with NBF (
- Published
- 2022