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3. Attributable mortality of infections caused by carbapenem-resistant Enterobacterales: results from a prospective, multinational case-control-control matched cohorts study (EURECA)

Author

Serna, Almudena de la, Monteau, Sophie, Palomo, Virginia, Soriano, Elena, Gutierrez, David, Moreno, Elisa, Sojo-Dorado, Jesus, Morales, Isabel, Maldonado, Natalia, Santis, Lucia Valiente de, Ciezar, Antonio Plata, Ruiz Mesa, Juan Diego, Diaz, Beatriz Sobrino, Gomez, Ignacio Marquez, Camacho, Ines Perez, Cano, Angela, Frutos-Adame, Azahara, Guzman-Puche, Julia, Gracia-Ahufinger, Irene, Perez-Nadales, Elena, Torre-Gimenez, Julian, Pyrpasopoulou, Athina, Iosifidis, Elias, Chorafa, Elsa, Radovanovic, Ivana, Petrovic, Sladjana, Cvetkovi, Slavica, Melentijevic, Srdjan-Sanja, Bicmen, Can, Senol, Gunes, Tubau, Fe, Camara, Jordi, Daniel Gumucio, Victor, Bassoulis, Dimitris, Deliolanis, John, Pitiriga, Vassiliki Ch., Triarides, Nikolaos, Argiti, Efstathia, Legakis, Nikolaos J., Margarita, Kyriakidou, Gijón-Cordero, Desirée, Ruiz-Garbajosa, Patricia, Rossolini, Gian Maria, Nica, Maria, Talapan, Daniela, Medić, Deana, Prijić, Sanja Maričić, Caballero, Mireia Cantero, Ramírez, Lina M Parra, Bilgin, Hüseyin, Dalekos, George N., Stefos, Aggelos, Spyridis, Nikolaos, Michos, Athanasios, De Rosa, Francesco Giuseppe, Cavallo, Rossana, Petrosillo, Nicola, Dicaro, Antonio, Landini, Maria Paola, degli Atti, Marta Luisa Ciofi, Masanovic, Mileva, Matkovic, Dusan, Tsiodras, Sotirios, Blasi, Francesco, pasquale, Marta Di, Viscoli, Claudio, Vata, Andrei, Dorneanu, Olivia, Kapisyzi, Perlat, Vince, Adriana, Tsigou, Evdoxia, Maltezos, Efstratios, Komnos, Apostolos, Gogos, Charalampos, Franzetti, Fabio, Antonelli, Massimo, Lupse, Mihaela, Corneci, Dan, Tomescu, Dana, Georgescu, Anca, Bukarica, Ljiljana, Mitrović, Goran, Krstić, Nataša Lukić, Kurti, Arsim, Reuter, Sandra, Díaz-Pollán, Beatriz, Sabater, Julia Origüen, Muñoz, Patricia, Azap, Alpay, ancak, Banu, Sahin, Arife, Akalin, Halis, Paniagua-García, María, Bravo-Ferrer, Jose M., Pérez-Galera, Salvador, Kostyanev, Tomislav, de Kraker, Marlieke E.A., Feifel, Jan, Palacios-Baena, Zaira R., Schotsman, Joost, Cantón, Rafael, Daikos, George L., Carevic, Biljana, Dragovac, Gorana, Tan, Lionel K., Raka, Lul, Hristea, Adriana, Viale, Pierluigi, Akova, Murat, Cano, Ángela, Reguera, Jose María, Bartoloni, Alessandro, Florescu, Simin-Aysel, Benea, Serban, Asensio, Ángel, Korten, Volkan, Grundmann, Hajo, Goossens, Herman, Bonten, Marc J., Gutiérrez-Gutiérrez, Belén, and Rodríguez-Baño, Jesús

Published
2024
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4. THU-382 Lead-in cohort results from a phase 2 study of a novel 8-week combination regimen of Bemnifosbuvir and Ruzasvir in patients with chronic hepatitis C virus infection

Author

Jucov, Alina, primary, Conway, Brian, additional, Iliescu, Laura, additional, Mitrut, Paul, additional, Florescu, Simin, additional, Cernat, Roxana, additional, Ermacicova, Elena, additional, Lynch, Shannan, additional, Majarian, Marina, additional, Izmailyan, Sergey, additional, Zhou, Xiao-Jian, additional, Pietropaolo, Keith, additional, Belanger, Bruce, additional, Horga, Arantxa, additional, and Hammond, Janet, additional

Published
2024
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5. Carbapenem-Resistant NDM and OXA-48-like Producing K. pneumoniae: From Menacing Superbug to a Mundane Bacteria; A Retrospective Study in a Romanian Tertiary Hospital

Author

Lazar, Dragos Stefan, primary, Nica, Maria, additional, Dascalu, Amalia, additional, Oprisan, Corina, additional, Albu, Oana, additional, Codreanu, Daniel Romeo, additional, Kosa, Alma Gabriela, additional, Popescu, Corneliu Petru, additional, and Florescu, Simin Aysel, additional

Published
2024
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6. Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)

Author

de la Serna, Almudena, Monteau, Sophie, Palomo, Virginia, Soriano, Elena, Gutierrez, David, Moreno, Elisa, Palacios, Zaira, Morales, Isabel, Maldonado, Natalia, Ciezar, Antonio Plata, Ruiz Mesa, Juan Diego, Diaz, Beatriz Sobrino, Gomez, Ignacio Marquez, Camacho, Ines Perez, Frutos-Adame, Azahara, Guzman-Puche, Julia, Gracia-Ahufinger, Irene, Perez-Nadales, Elena, Torre-Gimenez, Julian, Pyrpasopoulou, Athina, Iosifidis, Elias, Chorafa, Elsa, Radovanovic, Ivana, Petrovic, Sladjana, Cvetkovi, Slavica, Melentijevic, Srdjan-Sanja, Bicmen, Can, Senol, Gunes, Tubau, Fe, Camara, Jordi, Gumucio, Victor Daniel, Bassoulis, Dimitris, Deliolanis, John, Pitiriga, Vassiliki Ch., Triarides, Nikolaos, Argiti, Efstathia, Legakis, Nikolaos J., Margarita, Kyriakidou, Gijón-Cordero, Desirée, Ruiz-Garbajosa, Patricia, Bartoloni, Alessandro, Rossolini, Gian Maria, Florescu, Simin-Aysel, Nica, Maria, Benea, Serban, Talapan, Daniela, Medić, Deana, Prijić, Sanja Maričić, Caballero, Mireia Cantero, Parra Ramírez, Lina M., Korten, Volkan, Bilgin, Hüseyin, Dalekos, George N., Stefos, Aggelos, Spyridis, Nikolaos, Michos, Athanasios, De Rosa, Francesco Giuseppe, Cavallo, Rossana, Petrosillo, Nicola, Dicaro, Antonio, Landini, Maria Paola, Ciofi degli Atti, Marta Luisa, Masanovic, Mileva, Matkovic, Dusan, Tsiodras, Sotirios, Blasi, Francesco, Di pasquale, Marta, Viscoli, Claudio, Vata, Andrei, Dorneanu, Olivia, Kapisyzi, Perlat, Vince, Adriana, Tsigou, Evdoxia, Maltezos, Efstratios, Komnos, Apostolos, Gogos, Charalampos, Franzetti, Fabio, Antonelli, Massimo, Lupse, Mihaela, Corneci, Dan, Tomescu, Dana, Georgescu, Anca, Bukarica, Ljiljana, Mitrović, Goran, Krstić, Nataša Lukić, Kurti, Arsim, Díaz-Pollán, Beatriz, Sabater, Julia Origüen, Muñoz, Patricia, Azap, Alpay, Sancak, Banu, Sahin, Arife, Akalin, Halis, Pérez-Galera, Salvador, Bravo-Ferrer, Jose M., Paniagua, María, Kostyanev, Tomislav, de Kraker, Marlieke E.A., Feifel, Jan, Sojo-Dorado, Jesús, Schotsman, Joost, Cantón, Rafael, Daikos, George L., Carevic, Biljana, Dragovac, Gorana, Tan, Lionel K., Raka, Lul, Hristea, Adriana, Viale, Pierluigi, Akova, Murat, Reguera, Jose María, Valiente de Santis, Lucía, Torre-Cisneros, Julián, Cano, Ángela, Roilides, Emmanuel, Radulovic, Lili, Kirakli, Cenk, Shaw, Evelyn, Falagas, Matthew E., Pintado, Vicente, Goossens, Herman, Bonten, Marc J., Gutiérrez-Gutiérrez, Belén, and Rodriguez-Baño, Jesús

Published
2023
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7. Epidemiological and clinical characteristics of patients with monkeypox in the GeoSentinel Network: a cross-sectional study

Author

Blumberg, Lucille, Chaussade, Hélène, Desclaux, Arnaud, Florence, Eric, Aysel Florescu, Simin, Glans, Hedvig, Glynn, Marielle, Goorhuis, Abraham, Klein, Marina, Malvy, Denis, McCollum, Andrea, Muñoz, José, Nguyen, Duc, Quilter, Laura, Rothe, Camilla, Soentjens, Patrick, Tumiotto, Camille, Vanhamel, Jef, Angelo, Kristina M, Smith, Teresa, Camprubí-Ferrer, Daniel, Balerdi-Sarasola, Leire, Díaz Menéndez, Marta, Servera-Negre, Guillermo, Barkati, Sapha, Duvignaud, Alexandre, Huber, Kristina L B, Chakravarti, Arpita, Bottieau, Emmanuel, Greenaway, Christina, Grobusch, Martin P, Mendes Pedro, Diogo, Asgeirsson, Hilmir, Popescu, Corneliu Petru, Martin, Charlotte, Licitra, Carmelo, de Frey, Albie, Schwartz, Eli, Beadsworth, Michael, Lloveras, Susana, Larsen, Carsten S, Guagliardo, Sarah Anne J, Whitehill, Florence, Huits, Ralph, Hamer, Davidson H, Kozarsky, Phyllis, and Libman, Michael

Published
2023
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8. Blood Culture Negative Endocarditis; What Do Concurrent Cardiac Disorders Tell Us?

Author

Filiz, Mine, primary, Erdem, Hakan, additional, Ankarali, Handan, additional, Puca, Edmond, additional, Ruch, Yvon, additional, Santos, Lurdes, additional, Ghanem-Zoubi, Nesrin, additional, Argemi, Xavier, additional, Hansmann, Yves, additional, Guner, Rahmet, additional, Tonziello, Gilda, additional, Mazzucotelli, Jean-Philippe, additional, Como, Najada, additional, Kose, Sukran, additional, Batirel, Ayse, additional, Inan, Asuman, additional, Tulek, Necla, additional, Pekok, Abdullah Umut, additional, Khan, Ejaz Ahmed, additional, Iyisoy, Atilla, additional, Meric-Koc, Meliha, additional, Kaya-Kalem, Ayse, additional, Martins, Pedro Palma, additional, Hasanoglu, Imran, additional, Silva-Pinto, André, additional, Oztoprak, Nefise, additional, Duro, Raquel, additional, Almajid, Fahad, additional, Dogan, Mustafa, additional, Dauby, Nicolas, additional, Gunst, Jesper Damsgaard, additional, Tekin, Recep, additional, Konopnicki, Deborah, additional, Petrosillo, Nicola, additional, Bozkurt, Ilkay, additional, Ramahi, Jamal Wadi Al, additional, Popescu, Corneliu, additional, Balkan, Ilker Inanc, additional, Ozer-Balin, Safak, additional, Zupanc, Tatjana Lejko, additional, Cascio, Antonio, additional, Dumitru, Irina Magdalena, additional, Erdem, Aysegul, additional, Ersoz, Gulden, additional, Tasbakan, Meltem, additional, Ajamieh, Oday Abu, additional, Sirmatel, Fatma, additional, Florescu, Simin, additional, Gulsun, Serda, additional, Ozkaya, Hacer Deniz, additional, Sari, Sema, additional, Tosun, Selma, additional, Avci, Meltem, additional, Cag, Yasemin, additional, Celebi, Guven, additional, Sagmak-Tartar, Ayse, additional, Karakus, Sumeyra, additional, Sener, Alper, additional, Dedej, Arjeta, additional, Oncu, Serkan, additional, Vecchio, Rosa Fontana Del, additional, Ozturk-Engin, Derya, additional, and Agalar, Canan, additional

Published
2024
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9. Non-toxigenic Corynebacterium diphtheriae cutaneous infections among two injecting drug-users with HIV/Tuberculosis coinfection from Bucharest, Romania

Author

Florescu, Simin Aysel, primary, Ianache, Irina C., additional, Chirila, Claudia, additional, Enciu, Bianca Georgiana, additional, Oprea, Mihaela, additional, Dinu, Sorin, additional, Sirbu, Anca, additional, Nica, Maria, additional, Popescu, Corneliu Petru, additional, Oprea, Cristiana, additional, and Ene, Luminița, additional

Published
2024
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11. Attributable mortality of infections caused by carbapenem-resistant Enterobacterales: results from a prospective, multinational case-control-control matched cohorts study (EURECA)

Author

Paniagua-García, María, primary, Bravo-Ferrer, Jose M., additional, Pérez-Galera, Salvador, additional, Kostyanev, Tomislav, additional, de Kraker, Marlieke E.A., additional, Feifel, Jan, additional, Palacios-Baena, Zaira R., additional, Schotsman, Joost, additional, Cantón, Rafael, additional, Daikos, George L., additional, Carevic, Biljana, additional, Dragovac, Gorana, additional, Tan, Lionel K., additional, Raka, Lul, additional, Hristea, Adriana, additional, Viale, Pierluigi, additional, Akova, Murat, additional, Cano, Ángela, additional, Reguera, Jose María, additional, Bartoloni, Alessandro, additional, Florescu, Simin-Aysel, additional, Benea, Serban, additional, Bukarica, Ljiljana, additional, Asensio, Ángel, additional, Korten, Volkan, additional, Grundmann, Hajo, additional, Goossens, Herman, additional, Bonten, Marc J., additional, Gutiérrez-Gutiérrez, Belén, additional, Rodríguez-Baño, Jesús, additional, Serna, Almudena de la, additional, Monteau, Sophie, additional, Palomo, Virginia, additional, Soriano, Elena, additional, Gutierrez, David, additional, Moreno, Elisa, additional, Sojo-Dorado, Jesus, additional, Morales, Isabel, additional, Maldonado, Natalia, additional, Santis, Lucia Valiente de, additional, Ciezar, Antonio Plata, additional, Ruiz Mesa, Juan Diego, additional, Diaz, Beatriz Sobrino, additional, Gomez, Ignacio Marquez, additional, Camacho, Ines Perez, additional, Cano, Angela, additional, Frutos-Adame, Azahara, additional, Guzman-Puche, Julia, additional, Gracia-Ahufinger, Irene, additional, Perez-Nadales, Elena, additional, Torre-Gimenez, Julian, additional, Pyrpasopoulou, Athina, additional, Iosifidis, Elias, additional, Chorafa, Elsa, additional, Radovanovic, Ivana, additional, Petrovic, Sladjana, additional, Cvetkovi, Slavica, additional, Melentijevic, Srdjan-Sanja, additional, Bicmen, Can, additional, Senol, Gunes, additional, Tubau, Fe, additional, Camara, Jordi, additional, Daniel Gumucio, Victor, additional, Bassoulis, Dimitris, additional, Deliolanis, John, additional, Pitiriga, Vassiliki Ch., additional, Triarides, Nikolaos, additional, Argiti, Efstathia, additional, Legakis, Nikolaos J., additional, Margarita, Kyriakidou, additional, Gijón-Cordero, Desirée, additional, Ruiz-Garbajosa, Patricia, additional, Rossolini, Gian Maria, additional, Nica, Maria, additional, Talapan, Daniela, additional, Medić, Deana, additional, Prijić, Sanja Maričić, additional, Caballero, Mireia Cantero, additional, Ramírez, Lina M Parra, additional, Bilgin, Hüseyin, additional, Dalekos, George N., additional, Stefos, Aggelos, additional, Spyridis, Nikolaos, additional, Michos, Athanasios, additional, De Rosa, Francesco Giuseppe, additional, Cavallo, Rossana, additional, Petrosillo, Nicola, additional, Dicaro, Antonio, additional, Landini, Maria Paola, additional, degli Atti, Marta Luisa Ciofi, additional, Masanovic, Mileva, additional, Matkovic, Dusan, additional, Tsiodras, Sotirios, additional, Blasi, Francesco, additional, pasquale, Marta Di, additional, Viscoli, Claudio, additional, Vata, Andrei, additional, Dorneanu, Olivia, additional, Kapisyzi, Perlat, additional, Vince, Adriana, additional, Tsigou, Evdoxia, additional, Maltezos, Efstratios, additional, Komnos, Apostolos, additional, Gogos, Charalampos, additional, Franzetti, Fabio, additional, Antonelli, Massimo, additional, Lupse, Mihaela, additional, Corneci, Dan, additional, Tomescu, Dana, additional, Georgescu, Anca, additional, Mitrović, Goran, additional, Krstić, Nataša Lukić, additional, Kurti, Arsim, additional, Reuter, Sandra, additional, Díaz-Pollán, Beatriz, additional, Sabater, Julia Origüen, additional, Muñoz, Patricia, additional, Azap, Alpay, additional, ancak, Banu, additional, Sahin, Arife, additional, and Akalin, Halis, additional

Published
2024
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14. Training in infectious diseases across Europe in 2021 – a survey on training delivery, content and assessment

Author

Ahl, Jonas, Ambrozaitis, Arvydas, Azap, Alpay, Beović, Bojana, Castelli, Francesco, Cisneros, José Miguel, Constantinou, Costas, Van Delden, Christian, De Barra, Eoghan, De Munter, Paul, Džupová, Olga, Fätkenheuer, Gerd, Flisiak, Robert, Florescu, Simin Aysel, Fsadni, Claudia, Holmberg, Ville, Jensen-Fangel, Søren, Koehler, Philipp, Kristjánsson, Már, Lind, Andreas, Michos, Athanasios, Miller, Alastair, Muller, Zsofia, Oliveira, Joaquim, Paul, Mical, Sal, Ertan, Santini, Marija, Sargsyants, Narina, Soják, L'ubomir, Soodla, Pilleriin, Staub, Therese, Thalhammer, Florian, Verbon, Annelies, Verdon, Renaud, Wegrzyn, Zbigniew, Brockhoff, Ronja A., Hicks, Scott R., Salmanton-García, Jon, Dušek, Davorka, Stahl, Jean-Paul, Beeching, Nick J., and Cornely, Oliver A.

Published
2021
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16. Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)

Author

Pérez-Galera, Salvador, primary, Bravo-Ferrer, Jose M., additional, Paniagua, María, additional, Kostyanev, Tomislav, additional, de Kraker, Marlieke E.A., additional, Feifel, Jan, additional, Sojo-Dorado, Jesús, additional, Schotsman, Joost, additional, Cantón, Rafael, additional, Daikos, George L., additional, Carevic, Biljana, additional, Dragovac, Gorana, additional, Tan, Lionel K., additional, Raka, Lul, additional, Hristea, Adriana, additional, Viale, Pierluigi, additional, Akova, Murat, additional, Reguera, Jose María, additional, Valiente de Santis, Lucía, additional, Torre-Cisneros, Julián, additional, Cano, Ángela, additional, Roilides, Emmanuel, additional, Radulovic, Lili, additional, Kirakli, Cenk, additional, Shaw, Evelyn, additional, Falagas, Matthew E., additional, Pintado, Vicente, additional, Goossens, Herman, additional, Bonten, Marc J., additional, Gutiérrez-Gutiérrez, Belén, additional, Rodriguez-Baño, Jesús, additional, de la Serna, Almudena, additional, Monteau, Sophie, additional, Palomo, Virginia, additional, Soriano, Elena, additional, Gutierrez, David, additional, Moreno, Elisa, additional, Palacios, Zaira, additional, Morales, Isabel, additional, Maldonado, Natalia, additional, Ciezar, Antonio Plata, additional, Ruiz Mesa, Juan Diego, additional, Diaz, Beatriz Sobrino, additional, Gomez, Ignacio Marquez, additional, Camacho, Ines Perez, additional, Frutos-Adame, Azahara, additional, Guzman-Puche, Julia, additional, Gracia-Ahufinger, Irene, additional, Perez-Nadales, Elena, additional, Torre-Gimenez, Julian, additional, Pyrpasopoulou, Athina, additional, Iosifidis, Elias, additional, Chorafa, Elsa, additional, Radovanovic, Ivana, additional, Petrovic, Sladjana, additional, Cvetkovi, Slavica, additional, Melentijevic, Srdjan-Sanja, additional, Bicmen, Can, additional, Senol, Gunes, additional, Tubau, Fe, additional, Camara, Jordi, additional, Gumucio, Victor Daniel, additional, Bassoulis, Dimitris, additional, Deliolanis, John, additional, Pitiriga, Vassiliki Ch., additional, Triarides, Nikolaos, additional, Argiti, Efstathia, additional, Legakis, Nikolaos J., additional, Margarita, Kyriakidou, additional, Gijón-Cordero, Desirée, additional, Ruiz-Garbajosa, Patricia, additional, Bartoloni, Alessandro, additional, Rossolini, Gian Maria, additional, Florescu, Simin-Aysel, additional, Nica, Maria, additional, Benea, Serban, additional, Talapan, Daniela, additional, Medić, Deana, additional, Prijić, Sanja Maričić, additional, Caballero, Mireia Cantero, additional, Parra Ramírez, Lina M., additional, Korten, Volkan, additional, Bilgin, Hüseyin, additional, Dalekos, George N., additional, Stefos, Aggelos, additional, Spyridis, Nikolaos, additional, Michos, Athanasios, additional, De Rosa, Francesco Giuseppe, additional, Cavallo, Rossana, additional, Petrosillo, Nicola, additional, Dicaro, Antonio, additional, Landini, Maria Paola, additional, Ciofi degli Atti, Marta Luisa, additional, Masanovic, Mileva, additional, Matkovic, Dusan, additional, Tsiodras, Sotirios, additional, Blasi, Francesco, additional, Di pasquale, Marta, additional, Viscoli, Claudio, additional, Vata, Andrei, additional, Dorneanu, Olivia, additional, Kapisyzi, Perlat, additional, Vince, Adriana, additional, Tsigou, Evdoxia, additional, Maltezos, Efstratios, additional, Komnos, Apostolos, additional, Gogos, Charalampos, additional, Franzetti, Fabio, additional, Antonelli, Massimo, additional, Lupse, Mihaela, additional, Corneci, Dan, additional, Tomescu, Dana, additional, Georgescu, Anca, additional, Bukarica, Ljiljana, additional, Mitrović, Goran, additional, Krstić, Nataša Lukić, additional, Kurti, Arsim, additional, Díaz-Pollán, Beatriz, additional, Sabater, Julia Origüen, additional, Muñoz, Patricia, additional, Azap, Alpay, additional, Sancak, Banu, additional, Sahin, Arife, additional, and Akalin, Halis, additional

Published
2023
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17. Epidemiological and clinical characteristics of patients with monkeypox in the GeoSentinel Network: a cross-sectional study

Author

Angelo, Kristina M, primary, Smith, Teresa, additional, Camprubí-Ferrer, Daniel, additional, Balerdi-Sarasola, Leire, additional, Díaz Menéndez, Marta, additional, Servera-Negre, Guillermo, additional, Barkati, Sapha, additional, Duvignaud, Alexandre, additional, Huber, Kristina L B, additional, Chakravarti, Arpita, additional, Bottieau, Emmanuel, additional, Greenaway, Christina, additional, Grobusch, Martin P, additional, Mendes Pedro, Diogo, additional, Asgeirsson, Hilmir, additional, Popescu, Corneliu Petru, additional, Martin, Charlotte, additional, Licitra, Carmelo, additional, de Frey, Albie, additional, Schwartz, Eli, additional, Beadsworth, Michael, additional, Lloveras, Susana, additional, Larsen, Carsten S, additional, Guagliardo, Sarah Anne J, additional, Whitehill, Florence, additional, Huits, Ralph, additional, Hamer, Davidson H, additional, Kozarsky, Phyllis, additional, Libman, Michael, additional, Blumberg, Lucille, additional, Chaussade, Hélène, additional, Desclaux, Arnaud, additional, Florence, Eric, additional, Aysel Florescu, Simin, additional, Glans, Hedvig, additional, Glynn, Marielle, additional, Goorhuis, Abraham, additional, Klein, Marina, additional, Malvy, Denis, additional, McCollum, Andrea, additional, Muñoz, José, additional, Nguyen, Duc, additional, Quilter, Laura, additional, Rothe, Camilla, additional, Soentjens, Patrick, additional, Tumiotto, Camille, additional, and Vanhamel, Jef, additional

Published
2023
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19. A Randomized Clinical Trial of Regdanvimab in High-Risk Patients With Mild-to-Moderate Coronavirus Disease 2019

Author

Kim, Jin Yong, primary, Săndulescu, Oana, additional, Preotescu, Liliana-Lucia, additional, Rivera-Martínez, Norma E, additional, Dobryanska, Marta, additional, Birlutiu, Victoria, additional, Miftode, Egidia G, additional, Gaibu, Natalia, additional, Caliman-Sturdza, Olga, additional, Florescu, Simin-Aysel, additional, Shi, Hye Jin, additional, Streinu-Cercel, Anca, additional, Streinu-Cercel, Adrian, additional, Lee, Sang Joon, additional, Kim, Sung Hyun, additional, Chang, Ilsung, additional, Bae, Yun Ju, additional, Suh, Jee Hye, additional, Chung, Da Rae, additional, Kim, Sun Jung, additional, Kim, Mi Rim, additional, Lee, Seul Gi, additional, Park, Gahee, additional, and Eom, Joong Sik, additional

Published
2022
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21. Assessment of the Humoral Immune Response Following COVID-19 Vaccination in Healthcare Workers: A One Year Longitudinal Study

Author

Chivu-Economescu, Mihaela, primary, Vremera, Teodora, additional, Ruta, Simona Maria, additional, Grancea, Camelia, additional, Leustean, Mihaela, additional, Chiriac, Daniela, additional, David, Adina, additional, Matei, Lilia, additional, Diaconu, Carmen C., additional, Gatea, Adina, additional, Ilie, Ciprian, additional, Radu, Iuliana, additional, Cornienco, Ana Maria, additional, Iancu, Luminita Smaranda, additional, Cirstoiu, Catalin, additional, Pop, Corina Silvia, additional, Petru, Radu, additional, Strambu, Victor, additional, Malciolu, Stefan, additional, Popescu, Corneliu Petru, additional, Florescu, Simin Aysel, additional, Rafila, Alexandru, additional, Furtunescu, Florentina Ligia, additional, and Pistol, Adriana, additional

Published
2022
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22. Travel-related infections presenting in Europe: A 20-year analysis of EuroTravNet surveillance data

Author

Grobusch, Martin P, Weld, Leisa, Goorhuis, Abraham, Hamer, Davidson H, Schunk, Mirjam, Jordan, Sabine, Mockenhaupt, Frank P, Chappuis, François, Asgeirsson, Hilmir, Caumes, Eric, Jensenius, Mogens, Van Genderen, Perry JJ, Castelli, Francesco, López-Velez, Rogelio, Field, Vanessa, Bottieau, Emmanuel, Molina, Israel, Rapp, Christophe, Ménendez, Marta Díaz, Gkrania-Klotsas, Effrossyni, Larsen, Carsten S, Malvy, Denis, Lalloo, David, Gobbi, Federico, Florescu, Simin A, Gautret, Philippe, Schlagenhauf, Patricia, For EuroTravNet, Gkrania-Klotsas, Effrossyni [0000-0002-0930-8330], and Apollo - University of Cambridge Repository

Subjects
Geosentinel, Eurotravnet, Infectious diseases, Sentinel surveillance, travel
Abstract

Funder: Centers for Disease Control and Prevention, BACKGROUND: Disease epidemiology of (re-)emerging infectious diseases is changing rapidly, rendering surveillance of travel-associated illness important. METHODS: We evaluated travel-related illness encountered at EuroTravNet clinics, the European surveillance sub-network of GeoSentinel, between March 1, 1998 and March 31, 2018. FINDINGS: 103,739 ill travellers were evaluated, including 11,239 (10.8%) migrants, 89,620 (86.4%) patients seen post-travel, and 2,880 (2.8%) during and after travel. Despite increasing numbers of patient encounters over 20 years, the regions of exposure by year of clinic visits have remained stable. In 5-year increments, greater proportions of patients were migrants or visiting friends and relatives (VFR); business travel-associated illness remained stable; tourism-related illness decreased. Falciparum malaria was amongst the most-frequently diagnosed illnesses with 5,254 cases (5.1% of all patients) and the most-frequent cause of death (risk ratio versus all other illnesses 2.5:1). Animal exposures requiring rabies post-exposure prophylaxis increased from 0.7% (1998-2002) to 3.6% (2013-2018). The proportion of patients with seasonal influenza increased from zero in 1998-2002 to 0.9% in 2013-2018. There were 44 cases of viral haemorrhagic fever, most during the past five years. Arboviral infection numbers increased significantly as did the range of presenting arboviral diseases, dengue and chikungunya diagnoses increased by 2.6% and 1%, respectively. INTERPRETATION: Travel medicine must adapt to serve the changing profile of travellers, with an increase in migrants and persons visiting relatives and friends and the strong emergence of vector-borne diseases, with potential for further local transmission in Europe. FUNDING: This project was supported by a cooperative agreement (U50CK00189) between the Centers for Disease Control and Prevention to the International Society of Travel Medicine (ISTM) and funding from the ISTM and the Public Health Agency of Canada.

Published
2022
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23. Epidemiology, hospitalization cost, and socioeconomic burden of COVID-19 in Romania

Author

Laszlo Lorenzovici, Sz��kely, Andrea, Kal��, Zolt��n, Farkas-R��duly, Szabolcs, Ad��l Gy��ngyv��r Nagy, Nyulas, Bernadett, Precup, Andreea Mihaela, Pavel, Mihai Laurentiu, Gheorghe, Maria, Calcan, Alexandru, Tar, Gy��ngyi, Adam, Ovidiu, Bradacs, Aliz, Briciu, Violeta Tincuta, Florescu, Simin Aysel, Ianosi, Edith Simona, G��rbovan, Ovidiu, Siriopol, Dimitrie Cristian, and Vok��, Zolt��n

Published
2022
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24. Training in infectious diseases across Europe in 2021 – a survey on training delivery, content and assessment

Author

Brockhoff, Ronja A., primary, Hicks, Scott R., additional, Salmanton-García, Jon, additional, Dušek, Davorka, additional, Stahl, Jean-Paul, additional, Beeching, Nick J., additional, Cornely, Oliver A., additional, Ahl, Jonas, additional, Ambrozaitis, Arvydas, additional, Azap, Alpay, additional, Beović, Bojana, additional, Castelli, Francesco, additional, Cisneros, José Miguel, additional, Constantinou, Costas, additional, Van Delden, Christian, additional, De Barra, Eoghan, additional, De Munter, Paul, additional, Džupová, Olga, additional, Fätkenheuer, Gerd, additional, Flisiak, Robert, additional, Florescu, Simin Aysel, additional, Fsadni, Claudia, additional, Holmberg, Ville, additional, Jensen-Fangel, Søren, additional, Koehler, Philipp, additional, Kristjánsson, Már, additional, Lind, Andreas, additional, Michos, Athanasios, additional, Miller, Alastair, additional, Muller, Zsofia, additional, Oliveira, Joaquim, additional, Paul, Mical, additional, Sal, Ertan, additional, Santini, Marija, additional, Sargsyants, Narina, additional, Soják, L'ubomir, additional, Soodla, Pilleriin, additional, Staub, Therese, additional, Thalhammer, Florian, additional, Verbon, Annelies, additional, Verdon, Renaud, additional, and Wegrzyn, Zbigniew, additional

Published
2021
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25. 546. Therapeutic Effect of Regdanvimab in Patients with Mild to Moderate COVID-19: Day 28 Results from a Multicentre, Randomised, Controlled Pivotal Trial

Author

Ison, Michael G, primary, Kim, Jin Yong, additional, Sandulescu, Oana, additional, Preotescu, Liliana-Lucia, additional, Martinez, Norma Erendira Rivera, additional, Dobryanska, Marta, additional, Birlutiu, Victoria, additional, Miftode, Egidia Gabriela, additional, Gaibu, Natalia, additional, Caliman-Sturdza, Olga Adriana, additional, Florescu, Simin-Aysel, additional, Streinu-Cercel, Anca, additional, Lee, Sang Joon, additional, Kim, Sung Hyun, additional, Chang, Il Sung, additional, Bae, Yun Ju, additional, Suh, Jee Hye, additional, Kim, Mi Rim, additional, Chung, Da Re, additional, Kim, Sun Jung, additional, Lee, Seul Gi, additional, Park, Ga Hee, additional, and Eom, Joong Sik, additional

Published
2021
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26. Randomized Clinical Trial of Regdanvimab in High-Risk Patients With Mild-to-Moderate Coronavirus Disease 2019.

Author

Kim, Jin Yong, Săndulescu, Oana, Preotescu, Liliana-Lucia, Rivera-Martínez, Norma E, Dobryanska, Marta, Birlutiu, Victoria, Miftode, Egidia G, Gaibu, Natalia, Caliman-Sturdza, Olga, Florescu, Simin-Aysel, Shi, Hye Jin, Streinu-Cercel, Anca, Streinu-Cercel, Adrian, Lee, Sang Joon, Kim, Sung Hyun, Chang, Ilsung, Bae, Yun Ju, Suh, Jee Hye, Chung, Da Rae, and Kim, Sun Jung

Subjects
SARS-CoV-2, COVID-19, CLINICAL trials, CLINICAL trial registries, SARS-CoV-2 Omicron variant, CORONAVIRUS diseases
Abstract

Background We evaluated clinical effectiveness of regdanvimab (CT-P59), a severe acute respiratory syndrome coronavirus 2 neutralizing monoclonal antibody, in reducing disease progression and clinical recovery time in patients with mild-to-moderate coronavirus disease 2019 (COVID-19), primarily Alpha variant. Methods This was phase 3 of a phase 2/3 parallel-group, double-blind, randomized clinical trial. Outpatients with mild-to-moderate COVID-19 were randomized to single-dose regdanvimab 40 mg/kg (n = 656) or placebo (n = 659), alongside standard of care. The primary endpoint was COVID-19 disease progression up to day 28 among "high-risk" patients. Key secondary endpoints were disease progression (all randomized patients) and time to recovery (high-risk and all randomized patients). Results Of 1315 randomized patients, 880 were high risk; the majority were infected with Alpha variant. The proportion with disease progression was lower (14/446, 3.1% [95% confidence interval {CI}, 1.9%–5.2%] vs 48/434, 11.1% [95% CI, 8.4%–14.4%]; P  < .001) and time to recovery was shorter (median, 9.27 days [95% CI, 8.27–11.05 days] vs not reached [95% CI, 12.35–not calculable]; P  < .001) with regdanvimab than placebo. Consistent improvements were seen in all randomized and non-high-risk patients who received regdanvimab. Viral load reductions were more rapid with regdanvimab. Infusion-related reactions occurred in 11 patients (4/652 [0.6%] regdanvimab, 7/650 [1.1%] placebo). Treatment-emergent serious adverse events were reported in 5 of (4/652 [0.6%] regdanvimab and 1/650 [0.2%] placebo). Conclusions Regdanvimab was an effective treatment for patients with mild-to-moderate COVID-19, significantly reducing disease progression and clinical recovery time without notable safety concerns prior to the emergence of the Omicron variant. Clinical Trials Registration NCT04602000; 2020-003369-20 (EudraCT). [ABSTRACT FROM AUTHOR]

Published
2022
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29. Bacterial meningoencephalitis secondary to disseminated strongyloidiasis in a pacient with COVID-19.

Author

Banicioiu, Filofteia Cojanu, Chirila, Claudia, Toderan, Andreea, Florescu, Simin-Aysel, and Popescu, Corneliu Petru

Subjects
*STRONGYLOIDIASIS, *MENINGOENCEPHALITIS, *CEREBROSPINAL fluid examination, *PARASITIC diseases, *ADULT respiratory distress syndrome, *NEMATODE infections
Abstract

Introduction. Strongyloidiasis in a parasitic diseases determined by the intestinal nematode Strongyloides stercoralis. In most cases, this disease is asymptomatic, but the immunocompromised patients can develop severe forms like hyper infestation and disseminated strongyloidiasis. There severe forms of the disease are associated with bacteremias with gastrointestinal microorganisms which can determine infectious complication anywhere in the body. Bacterial meningitis is the most common complication of this kind. Case presentation. We present you the case of a 78 years old patient who initially presented in another hospital for suddenly installed aphasia. He was clinical and paraclinical evaluated and the suspected diagnosis was acute meningoencephalitis, so he was transferred in our hospital. This is a case about a patient with an immunocompromised status determined by recent infection with SARS-CoV-2 who was hospitalized and received prolonged corticosteroid therapy. The clinical examination performed at the admission shows a patient with mediocre general status, partially cooperative, partially time-spatial oriented and to one’s own person, discreet neck stiffness, anxious-depressive mood, with acute respiratory failure. A coproparasitological examination is performed which reveals the presence of filariform larvae of Strongyloides stercoralis in the stool. Also, a parasitic PCR test from a stool sample is positive for Strongyloides stercoralis. These clinical and paraclinical findings corroborated with those found in the cerebrospinal fluid examination establish the diagnosis: acute bacterial meningoencephalitis secondary to disseminated strongyloidiasis. During the disease’s evolution, he is confirmed with a new infection with SARS-CoV-2. He receives antiviral treatment, antiparasitic treatment, antibiotic treatment and symptomatic treatment. The evolution of the disease is favorable. Conclusions. The immunocompromised status of the patient determined the evolution of the infestation with Strongyloides stercoralis to a severe form complicated with acute bacterial meningoencephalitis. The difficulty in establishing the diagnosis of strongyloidiasis is represented by the fact that Romania is a non-endemic country for the infection with this parasite. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Histopathologically Confirmed Pulmonary Mucormycosis as a Complication of COVID-19: a Case Report from Romania and Insight into Pathology.

Author

GHERLAN, George Sebastian, HOARA, Maria Cristina, SMADU, Sebastian George, POPESCU, Corneliu Petru, IONESCU, Petronela, and FLORESCU, Simin-Aysel

Subjects
*COVID-19 pandemic, *MUCORMYCOSIS, *PATHOLOGY, *IRON chelates, *MYCOSES
Abstract

COVID-19 has proven to be an independent risk factor for secondary infectious complications. Amongst them, mucormycosis has recently been noticed more frequently than in the past. Caused by molds belonging to the Mucorales order, this is a rare, but potentially fatal infection unless adequately treated. Ear, nose and throat involvement is prevalent with often expansion to the orbit, sinuses or brain. Pulmonary, cutaneous and gastrointestinal infections are also recognized. Classical risk factors for progression to angioinvasive disease include poorly controlled diabetes mellitus, defects in phagocytic function (prolonged neutropenia, glucocorticoid treatment), immunosuppressive therapy associated with transplantation, malignancy, elevated levels of free iron as well as iron chelators (deferoxamine). In addition, immune dysregulation rendered by COVID-19 itself may contribute or solely lead to invasive mold disease. The largest experience comes from India, which has dealt with a challenging epidemic of COVID-19-associated mucormycosis (CAM). To our knowledge, no previous studies have reported CAM in Romania. We therefore present a case of severe COVID-19 pneumonia initially complicated by bacterial superinfection and secondary sepsis at admission in an unvaccinated 61-year-old male who presented in our clinic with respiratory failure and digestive symptoms. Although improvement occurred rapidly following antiviral, empiric large spectrum Intraantibiotics and pathogenic medication, unfavorable clinical course ensued later on. Biological and imaging investigations were consistent with pulmonary superinfection in the form of multiple different-sized upper right field opacities, which eventually evolved to form cavities. Differential diagnosis was thoroughly performed. Since unable to sterilize the lung by means of medication alone, the patient underwent major thoracic surgery with removal of the entire right lung. Microscopic study of the damaged tissue was able to determine the presence of broad, aseptate hyphae which morphologically belong to Mucorales. A diagnosis of pulmonary mucormycosis was established and proper antifungal treatment was initiated, with full recovery of the patient. [ABSTRACT FROM AUTHOR]

Published
2022
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31. Otitis with Aspergillus niger in a patient with SARS-CoV-2 and multiple comorbidities.

Author

Stoenescu, Andreea Florentina, Vancea, Geta, Ispas, Dana, Voicu-Pârvu, Nicoleta, Tudor, Nicoleta, Precup, Gabriela, Scurtu, Gabriela, Pișcu, Sebastian Alexandru, Popica, Andreea, Bontea, Raluca, Chirilă, Claudia, Sandu, Elena, Potârniche, Diana, Tăbăcaru, Octavian, Mischie, Daniela, Toderan, Andreea, Ceauşu, Emanoil, and Florescu, Simin-Aysel

Subjects
*ASPERGILLUS niger, *SARS-CoV-2, *OTITIS media, *MYOCARDIAL ischemia, *EAR canal, *SYMPTOMS
Abstract

Introduction. COVID-19 is associated with a significant incidence of bacterial and fungal superinfections and with the exacerbation of pre-existing infections, representing a diagnostic and therapeutic challenge. Case presentation. A 64-year-old woman, confirmed with COVID-19 by the SARS-CoV-2 antigen test, is hospitalized accusing fatigue, nausea, watery stools, cough and vertigo started 10 days ago, aggravated 4 days before the presentation. It also reports recurrent episodes of otalgia and otorrheic pluriantibiotic treatment in the last 2 months. From the personal pathological antecedents we remember: hypothyroidism, dyslipidemia, hypertension, ischemic heart disease, history of deep vein thrombosis (DVT) and secondary pulmonary thromboembolism, in chronic anticoagulant treatment. Pathological clinical signs at admission: bilateral basal crackling rales. Biologically, inflammatory syndrome is detected, and radiologically, interstitial-alveolar infiltrates in the lower lung fields. On day 3 of hospitalization, the patient shows purulent secretion in the right external auditory canal and the ENT consultation confirms chronic suppurative otitis media in acute onset. Bacteriological examination of otic secretion reveals Aspergillus niger. Antiviral treatment with Remdesivir is initiated, antibiotic therapy initiated at home with Azithromycin is continued for one day, then escalated to Ceftriaxone i.v. (in the context of clinical-paraclinical aggravation), systemic corticotherapy, anticoagulation with Dalteparin in the prophylactic regime of DVT, systemic treatment with Voriconazole p.o. (according to the antifungal program) and topical (local) with a slow favorable evolution. Conclusions. The association of COVID-19 with otitis with Aspergillus is a rare and particular clinical picture. [ABSTRACT FROM AUTHOR]

Published
2021
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32. SARS-CoV-2 infection in a child with Fanconi anemia and determined immunosuppressed status.

Author

Chirilă, Claudia, Vancea, Geta, Ispas, Dana, Voicu-Pârvu, Nicoleta, Tudor, Nicoleta, Scurtu, Gabriela, Stoenescu, Andreea Florentina, Popică, Andreea, Popescu, Raluca, Ceaușu, Emanoil, and Florescu, Simin-Aysel

Subjects
*FANCONI'S anemia, *SARS-CoV-2, *COVID-19 pandemic, *COVID-19, *BONE marrow transplantation
Abstract

Introduction. SARS-CoV-2 virus infection affects all age groups. In children, the infection mainly causes asymptomatic or mildly symptomatic forms of the disease, regardless of their immune status. Case presentation. We describe the case of a 7-year-old male child, known to have Fanconi anemia, scheduled for bone marrow transplantation. The patient comes from a family outbreak of COVID-19, which is why he was tested for SARS-CoV-2 infection. He is asymptomatic at the time of admission to our clinic. The clinical examination performed at the time of admission shows a patient in good general condition, afebrile, with pale skin and mucous membranes, without respiratory changes. Para-clinically, severe neutropenia, severe normochromic normocytic anemia and severe thrombocytopenia are detected, for which transfusions of erythrocyte mass and platelet mass are performed. Due to the immunocompromised status, antibiotic therapy is instituted. If necessary, symptomatic treatment is administered. The evolution is favorable, and the SARS-CoV-2 RT-PCR control test is negative on the eighth day of hospitalization. Conclusions. Immunocompromised status is not a major risk factor for severe COVID-19 in children. [ABSTRACT FROM AUTHOR]

Published
2021
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33. COVID-19 in a child with multiple comorbidities.

Author

Sandu, Elena-Cristina, Vancea, Geta, Voicu-Pârvu, Nicoleta, Ispas, Dana, Scurtu, Gabriela, Tudor, Nicoleta, Stoenescu, Andreea Florentina, Chirilă, Claudia, Popescu, Raluca, Florescu, Simin-Aysel, and Ceaușu, Emanoil

Subjects
*COVID-19, *COMORBIDITY, *NEUROLOGICAL disorders, *MYELOMENINGOCELE, *SARS-CoV-2, *DIAGNOSIS
Abstract

A female child, 1 year-old and 2 months, diagnosed with multiple neurological conditions, including myelomeningocele and operated hydrocephalus, was diagnosed with SARS-CoV-2 in October 2020 and hospitalized in our clinic. At the time of the onset of the disease, the patient had a febrile episode, laboratory blood tests showed a slightly increased biological inflammatory syndrome, and mixed pneumonia was described radiologically. Thus, antibiotic treatment was initiated, with laboratory tests and control imaging within normal limits after several days of admission. Being an institutionalized child, according to the epidemiological recommendations of that time, she was hospitalized in our clinic during the 14 days of the illness. Thus, on the 15th day of the disease she was discharged, with negative SARS-CoV-2 control RT-PCR, with good general condition, afebrile over 10 days. [ABSTRACT FROM AUTHOR]

Published
2021
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34. Child with SARS-CoV-2 infection and acute lymphoblastic leukemia.

Author

Bontea, Raluca, Vancea, Geta, Ispas, Dana, Tudor, Nicoleta, Voicu, Nicoleta, Iordache, Cristina, Scurtu, Gabriela, Stoenescu, Andreea, Popică, Andreea, Chirilă, Claudia, Florescu, Simin-Aysel, Ceaușu, Emanoil, and Calistru, Petre

Subjects
*LYMPHOBLASTIC leukemia, *COVID-19, *SARS-CoV-2, *ACUTE leukemia, *JUVENILE diseases
Abstract

Introduction. Coronavirus disease 2019 (COVID-19) frequently leads to asymptomatic or mild infectious disease evolution in children. Case presentation. We present the case of a 3 year old girl, known with acute lymphoblastic leukemia in chemotherapy treatment at that time. She had an asymptomatic form of COVID-19 but with important paraclinical changes. The evolution was favorable under the treatment initiated with antibiotics, corticotherapy, gastric protector and symptomatic treatment if necessary. Conclusion. Management of children with COVID-19 and other comorbidities remains a challenge given the few data currently in the literature. [ABSTRACT FROM AUTHOR]

Published
2021
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