196 results on '"Fonseca, V."'
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2. The queens of the stingless bees: from egg to adult
- Author
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Bueno, F. G. B., dos Santos, C. F., Otesbelgue, A., Menezes, C., van Veen, J., Blochtein, B., Gloag, R., Heard, T., Imperatriz-Fonseca, V. L., and Alves, D. A.
- Published
- 2023
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3. Genetic and morphometric variation in Schwarziana quadripunctata and Schwarziana mourei (Hymenoptera: Apidae: Meliponini)
- Author
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Oi, C. A., Oliveira-Silva, R. A., Francoy, T. M., Imperatriz-Fonseca, V. L., and Del Lama, M. A.
- Published
- 2022
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4. A CONFLUÊNCIA ENTRE CIÊNCIA E ARTE: ILUSTRAÇÃO CIENTÍFICA COMO FERRAMENTA FACILITADORA NO ENSINO DA CLASSE INSECTA
- Author
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FONSECA, V. B., primary and COSTA, T. S., additional
- Published
- 2023
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5. Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago
- Author
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Perrone, G, Giuffrida, M, Abu-Zidan, F, Kruger, V, Livrini, M, Petracca, G, Rossi, G, Tarasconi, A, Tian, B, Bonati, E, Mentz, R, Mazzini, F, Campana, J, Gasser, E, Kafka-Ritsch, R, Felsenreich, D, Dawoud, C, Riss, S, Gomes, C, Gomes, F, Gonzaga, R, Canton, C, Pereira, B, Fraga, G, Zem, L, Cordeiro-Fonseca, V, de Mesquita Tauil, R, Atanasov, B, Belev, N, Kovachev, N, Melendez, L, Dimova, A, Dimov, S, Zelic, Z, Augustin, G, Bogdanic, B, Moric, T, Chouillard, E, Bajul, M, De Simone, B, Panis, Y, Esposito, F, Notarnicola, M, Lauka, L, Fabbri, A, Hentati, H, Fnaiech, I, Aurelien, V, Bougard, M, Roulet, M, Demetrashvili, Z, Pipia, I, Merabishvili, G, Bouliaris, K, Koukoulis, G, Doudakmanis, C, Xenaki, S, Chrysos, E, Kokkinakis, S, Vassiliu, P, Michalopoulos, N, Margaris, I, Kechagias, A, Avgerinos, K, Katunin, J, Lostoridis, E, Nagorni, E, Pujante, A, Mulita, F, Maroulis, I, Vailas, M, Marinis, A, Siannis, I, Bourbouteli, E, Manatakis, D, Tasis, N, Acheimastos, V, Maria, S, Stylianos, K, Kuzeridis, H, Korkolis, D, Fradelos, E, Kavalieratos, G, Petropoulou, T, Polydorou, A, Papacostantinou, I, Triantafyllou, T, Kimpizi, D, Theodorou, D, Toutouzas, K, Chamzin, A, Frountzas, M, Schizas, D, Karavokyros, I, Syllaios, A, Charalabopoulos, A, Boura, M, Baili, E, Ioannidis, O, Loutzidou, L, Anestiadou, E, Tsouknidas, I, Petrakis, G, Polenta, E, Bains, L, Gupta, R, Singh, S, Khanduri, A, Bala, M, Kedar, A, Pisano, M, Podda, M, Pisanu, A, Martines, G, Trigiante, G, Lantone, G, Agrusa, A, Di Buono, G, Buscemi, S, Veroux, M, Gioco, R, Veroux, G, Oragano, L, Zonta, S, Lovisetto, F, Feo, C, Pesce, A, Fabbri, N, Marino, F, Perrone, F, Vincenti, L, Papagni, V, Picciariello, A, Rossi, S, Picardi, B, Del Monte, S, Visconti, D, Osella, G, Petruzzelli, L, Pignata, G, Andreuccetti, J, D'Alessio, R, Buonfantino, M, Guaitoli, E, Spinelli, S, Sampietro, G, Corbellini, C, Lorusso, L, Frontali, A, Pezzoli, I, Bonomi, A, Chierici, A, Cotsoglou, C, Manca, G, Delvecchio, A, Musa, N, Casati, M, Letizia, L, Abate, E, Ercolani, G, D'Acapito, F, Solaini, L, Guercioni, G, Cicconi, S, Sasia, D, Borghi, F, Giraudo, G, Sena, G, Castaldo, P, Cardamone, E, Portale, G, Zuin, M, Spolverato, Y, Esposito, M, Isernia, R, Di Salvo, M, Manunza, R, Esposito, G, Agus, M, Asti, E, Bernardi, D, Tonucci, T, Luppi, D, Casadei, M, Bonilauri, S, Pezzolla, A, Panebianco, A, Laforgia, R, De Luca, M, Zese, M, Parini, D, Jovine, E, De Sario, G, Lombardi, R, Aprea, G, Palomba, G, Capuano, M, Argenio, G, Orio, G, Armellino, M, Troian, M, Guerra, M, Nagliati, C, Biloslavo, A, Germani, P, Aizza, G, Monsellato, I, Chahrour, A, Anania, G, Bombardini, C, Bagolini, F, Sganga, G, Fransvea, P, Bianchi, V, Boati, P, Ferrara, F, Palmieri, F, Cianci, P, Gattulli, D, Restini, E, Cillara, N, Cannavera, A, Nita, G, Sarnari, J, Roscio, F, Clerici, F, Scandroglio, I, Berti, S, Cadeo, A, Filippelli, A, Conti, L, Grassi, C, Cattaneo, G, Pighin, M, Papis, D, Gambino, G, Bertino, V, Schifano, D, Prando, D, Fogato, L, Cavallo, F, Ansaloni, L, Picheo, R, Pontarolo, N, Depalma, N, Spampinato, M, D'Ugo, S, Lepre, L, Capponi, M, Campa, R, Sarro, G, Dinuzzi, V, Olmi, S, Uccelli, M, Ferrari, D, Inama, M, Moretto, G, Fontana, M, Favi, F, Picariello, E, Rampini, A, Barberis, A, Azzinnaro, A, Oliva, A, Totaro, L, Benzoni, I, Ranieri, V, Capolupo, G, Carannante, F, Caricato, M, Ronconi, M, Casiraghi, S, Casole, G, Pantalone, D, Alemanno, G, Scheiterle, M, Ceresoli, M, Cereda, M, Fumagalli, C, Zanzi, F, Bolzon, S, Guerra, E, Lecchi, F, Cellerino, P, Ardito, A, Scaramuzzo, R, Balla, A, Lepiane, P, Tartaglia, N, Ambrosi, A, Pavone, G, Palini, G, Veneroni, S, Garulli, G, Ricci, C, Torre, B, Russo, I, Rottoli, M, Tanzanu, M, Belvedere, A, Milone, M, Manigrasso, M, De Palma, G, Piccoli, M, Pattacini, G, Magnone, S, Bertoli, P, Massucco, P, Palisi, M, Luzzi, A, Fleres, F, Clarizia, G, Spolini, A, Kobe, Y, Toma, T, Shimamura, F, Parker, R, Ranketi, S, Mitei, M, Svagzdys, S, Pauzas, H, Zilinskas, J, Poskus, T, Kryzauskas, M, Jakubauskas, M, Zakaria, A, Zakaria, Z, Wong, M, Jusoh, A, Zakaria, M, Cruz, D, Elizalde, A, Reynaud, A, Hernandez, E, Monroy, J, Hinojosa-Ugarte, D, Quiodettis, M, Du Bois, M, Latorraca, J, Major, P, Pedziwiatr, M, Pisarska-Adamczyk, M, Waledziak, M, Kwiatkowski, A, Czyzykowski, L, da Costa, S, Ferreira, A, Almeida, F, Rocha, R, Carneiro, C, Perez, D, Carvas, J, Rocha, C, Ferreira, C, Marques, R, Fernandes, U, Leao, P, Goulart, A, Pereira, R, Patrocinio, S, de Mendonca, N, Manso, M, Morais, H, Cardoso, P, Calu, V, Miron, A, Toma, E, Gachabayov, M, Abdullaev, A, Litvin, A, Nechay, T, Tyagunov, A, Yuldashev, A, Bradley, A, Wilson, M, Panyko, A, Lateckova, Z, Lacko, V, Lesko, D, Soltes, M, Radonak, J, Turrado-Rodriguez, V, Termes-Serra, R, Morales-Sevillano, X, Lapolla, P, Mingoli, A, Brachini, G, Degiuli, M, Sofia, S, Reddavid, R, de Manzoni Garberini, A, Buffone, A, del Pozo, E, Aparicio-Sanchez, D, Dos Barbeito, S, Estaire-Gomez, M, Viton-Herrero, R, de los Angeles Gil Olarte-Marquez, M, Gil-Martinez, J, Alconchel, F, Nicolas-Lopez, T, Rahy-Martin, A, Pelloni, M, Banolas-Suarez, R, Mendoza-Moreno, F, Nisa, F, Diez-Alonso, M, Rodas, M, Agundez, M, Andres, M, Moreira, C, Perez, A, Ponce, I, Gonzalez-Castillo, A, Membrilla-Fernandez, E, Salvans, S, Serradilla-Martin, M, Pardo, P, Rivera-Alonso, D, Dziakova, J, Huguet, J, Valle, N, Ruiz, E, Valcarcel, C, Moreno, C, Salazar, Y, Garcia, J, Mico, S, Lopez, J, Farre, S, Gomez, M, Petit, N, Titos-Garcia, A, Aranda-Narvaez, J, Romacho-Lopez, L, Sanchez-Guillen, L, Aranaz-Ostariz, V, Bosch-Ramirez, M, Martinez-Perez, A, Martinez-Lopez, E, Sebastian-Tomas, J, Jimenez-Riera, G, Jimenez-Vega, J, Cuellar, J, Campos-Serra, A, Munoz-Campana, A, Gracia-Roman, R, Alegre, J, Pinto, F, O'Sullivan, S, Antona, F, Jimenez, B, Lopez-Sanchez, J, Carmona, Z, Fernandez, R, Sierra, I, de Leon, L, Moreno, V, Iglesias, E, Cumplido, P, Bravo, A, Simo, I, Dominguez, C, Caamano, A, Lozano, R, Martinez, M, Torres, A, de Quiros, J, Pellino, G, Cloquell, M, Moller, E, Jalal-Eldin, S, Abdoun, A, Hamid, H, Lohsiriwat, V, Mongkhonsupphawan, A, Baraket, O, Ayed, K, Abbassi, I, Ali, A, Ammar, H, Kchaou, A, Tlili, A, Zribi, I, Colak, E, Polat, S, Koylu, Z, Guner, A, Usta, M, Reis, M, Mantoglu, B, Gonullu, E, Akin, E, Altintoprak, F, Bayhan, Z, Firat, N, Isik, A, Memis, U, Bayrak, M, Altintas, Y, Kara, Y, Bozkurt, M, Kocatas, A, Das, K, Seker, A, Ozer, N, Atici, S, Tuncer, K, Kaya, T, Ozkan, Z, Ilhan, O, Agackiran, I, Uzunoglu, M, Demirbas, E, Altinel, Y, Meric, S, Hacim, N, Uymaz, D, Omarov, N, Balik, E, Tebala, G, Khalil, H, Rana, M, Khan, M, Florence, C, Swaminathan, C, Leo, C, Liasis, L, Watfah, J, Trostchansky, I, Delgado, E, Pontillo, M, Latifi, R, Coimbra, R, Edwards, S, Lopez, A, Velmahos, G, Dorken, A, Gebran, A, Palmer, A, Oury, J, Bardes, J, Seng, S, Coffua, L, Ratnasekera, A, Egodage, T, Echeverria-Rosario, K, Armento, I, Napolitano, L, Sangji, N, Hemmila, M, Quick, J, Austin, T, Hyman, T, Curtiss, W, Mcclure, A, Cairl, N, Biffl, W, Truong, H, Schaffer, K, Reames, S, Banchini, F, Capelli, P, Coccolini, F, Sartelli, M, Bravi, F, Vallicelli, C, Agnoletti, V, Baiocchi, G, Catena, F, Perrone G., Giuffrida M., Abu-Zidan F., Kruger V. F., Livrini M., Petracca G. L., Rossi G., Tarasconi A., Tian B. W. C. A., Bonati E., Mentz R., Mazzini F. N., Campana J. P., Gasser E., Kafka-Ritsch R., Felsenreich D. M., Dawoud C., Riss S., Gomes C. A., Gomes F. C., Gonzaga R. A. T., Canton C. A. B., Pereira B. M., Fraga G. P., Zem L. G., Cordeiro-Fonseca V., de Mesquita Tauil R., Atanasov B., Belev N., Kovachev N., Melendez L. J. J., Dimova A., Dimov S., Zelic Z., Augustin G., Bogdanic B., Moric T., Chouillard E., Bajul M., De Simone B., Panis Y., Esposito F., Notarnicola M., Lauka L., Fabbri A., Hentati H., Fnaiech I., Aurelien V., Bougard M., Roulet M., Demetrashvili Z., Pipia I., Merabishvili G., Bouliaris K., Koukoulis G., Doudakmanis C., Xenaki S., Chrysos E., Kokkinakis S., Vassiliu P., Michalopoulos N., Margaris I., Kechagias A., Avgerinos K., Katunin J., Lostoridis E., Nagorni E. -A., Pujante A., Mulita F., Maroulis I., Vailas M., Marinis A., Siannis I., Bourbouteli E., Manatakis D. K., Tasis N., Acheimastos V., Maria S., Stylianos K., Kuzeridis H., Korkolis D., Fradelos E., Kavalieratos G., Petropoulou T., Polydorou A., Papacostantinou I., Triantafyllou T., Kimpizi D., Theodorou D., Toutouzas K., Chamzin A., Frountzas M., Schizas D., Karavokyros I., Syllaios A., Charalabopoulos A., Boura M., Baili E., Ioannidis O., Loutzidou L., Anestiadou E., Tsouknidas I., Petrakis G., Polenta E., Bains L., Gupta R., Singh S. K., Khanduri A., Bala M., Kedar A., Pisano M., Podda M., Pisanu A., Martines G., Trigiante G., Lantone G., Agrusa A., Di Buono G., Buscemi S., Veroux M., Gioco R., Veroux G., Oragano L., Zonta S., Lovisetto F., Feo C. V., Pesce A., Fabbri N., Marino F., Perrone F., Vincenti L., Papagni V., Picciariello A., Rossi S., Picardi B., Del Monte S. R., Visconti D., Osella G., Petruzzelli L., Pignata G., Andreuccetti J., D'Alessio R., Buonfantino M., Guaitoli E., Spinelli S., Sampietro G. M., Corbellini C., Lorusso L., Frontali A., Pezzoli I., Bonomi A., Chierici A., Cotsoglou C., Manca G., Delvecchio A., Musa N., Casati M., Letizia L., Abate E., Ercolani G., D'Acapito F., Solaini L., Guercioni G., Cicconi S., Sasia D., Borghi F., Giraudo G., Sena G., Castaldo P., Cardamone E., Portale G., Zuin M., Spolverato Y., Esposito M., Isernia R. M., Di Salvo M., Manunza R., Esposito G., Agus M., Asti E. L. G., Bernardi D. T., Tonucci T. P., Luppi D., Casadei M., Bonilauri S., Pezzolla A., Panebianco A., Laforgia R., De Luca M., Zese M., Parini D., Jovine E., De Sario G., Lombardi R., Aprea G., Palomba G., Capuano M., Argenio G., Orio G., Armellino M. F., Troian M., Guerra M., Nagliati C., Biloslavo A., Germani P., Aizza G., Monsellato I., Chahrour A. C., Anania G., Bombardini C., Bagolini F., Sganga G., Fransvea P., Bianchi V., Boati P., Ferrara F., Palmieri F., Cianci P., Gattulli D., Restini E., Cillara N., Cannavera A., Nita G. E., Sarnari J., Roscio F., Clerici F., Scandroglio I., Berti S., Cadeo A., Filippelli A., Conti L., Grassi C., Cattaneo G. M., Pighin M., Papis D., Gambino G., Bertino V., Schifano D., Prando D., Fogato L., Cavallo F., Ansaloni L., Picheo R., Pontarolo N., Depalma N., Spampinato M., D'Ugo S., Lepre L., Capponi M. G., Campa R. D., Sarro G., Dinuzzi V. P., Olmi S., Uccelli M., Ferrari D., Inama M., Moretto G., Fontana M., Favi F., Picariello E., Rampini A., Barberis A., Azzinnaro A., Oliva A., Totaro L., Benzoni I., Ranieri V., Capolupo G. T., Carannante F., Caricato M., Ronconi M., Casiraghi S., Casole G., Pantalone D., Alemanno G., Scheiterle M., Ceresoli M., Cereda M., Fumagalli C., Zanzi F., Bolzon S., Guerra E., Lecchi F., Cellerino P., Ardito A., Scaramuzzo R., Balla A., Lepiane P., Tartaglia N., Ambrosi A., Pavone G., Palini G. M., Veneroni S., Garulli G., Ricci C., Torre B., Russo I. S., Rottoli M., Tanzanu M., Belvedere A., Milone M., Manigrasso M., De Palma G. D., Piccoli M., Pattacini G. C., Magnone S., Bertoli P., Massucco P., Palisi M., Luzzi A. -P., Fleres F., Clarizia G., Spolini A., Kobe Y., Toma T., Shimamura F., Parker R., Ranketi S., Mitei M., Svagzdys S., Pauzas H., Zilinskas J., Poskus T., Kryzauskas M., Jakubauskas M., Zakaria A. D., Zakaria Z., Wong M. P. -K., Jusoh A. C., Zakaria M. N., Cruz D. R., Elizalde A. B. R., Reynaud A. B., Hernandez E. E. L., Monroy J. M. V. P., Hinojosa-Ugarte D., Quiodettis M., Du Bois M. E., Latorraca J., Major P., Pedziwiatr M., Pisarska-Adamczyk M., Waledziak M., Kwiatkowski A., Czyzykowski L., da Costa S. D., Pereira B., Ferreira A. R. O., Almeida F., Rocha R., Carneiro C., Perez D. P., Carvas J., Rocha C., Ferreira C., Marques R., Fernandes U., Leao P., Goulart A., Pereira R. G., Patrocinio S. D. D., de Mendonca N. G. G., Manso M. I. C., Morais H. M. C., Cardoso P. S., Calu V., Miron A., Toma E. A., Gachabayov M., Abdullaev A., Litvin A., Nechay T., Tyagunov A., Yuldashev A., Bradley A., Wilson M., Panyko A., Lateckova Z., Lacko V., Lesko D., Soltes M., Radonak J., Turrado-Rodriguez V., Termes-Serra R., Morales-Sevillano X., Lapolla P., Mingoli A., Brachini G., Degiuli M., Sofia S., Reddavid R., de Manzoni Garberini A., Buffone A., del Pozo E. P., Aparicio-Sanchez D., Dos Barbeito S., Estaire-Gomez M., Viton-Herrero R., de los Angeles Gil Olarte-Marquez M. a., Gil-Martinez J., Alconchel F., Nicolas-Lopez T., Rahy-Martin A. C., Pelloni M., Banolas-Suarez R., Mendoza-Moreno F., Nisa F. G. -M., Diez-Alonso M., Rodas M. E. V., Agundez M. C., Andres M. I. P., Moreira C. C. L., Perez A. L., Ponce I. A., Gonzalez-Castillo A. M., Membrilla-Fernandez E., Salvans S., Serradilla-Martin M., Pardo P. S., Rivera-Alonso D., Dziakova J., Huguet J. M., Valle N. P., Ruiz E. C., Valcarcel C. R., Moreno C. R., Salazar Y. T. M., Garcia J. J. R., Mico S. S., Lopez J. R., Farre S. P., Gomez M. S., Petit N. M., Titos-Garcia A., Aranda-Narvaez J. M., Romacho-Lopez L., Sanchez-Guillen L., Aranaz-Ostariz V., Bosch-Ramirez M., Martinez-Perez A., Martinez-Lopez E., Sebastian-Tomas J. C., Jimenez-Riera G., Jimenez-Vega J., Cuellar J. A. N., Campos-Serra A., Munoz-Campana A., Gracia-Roman R., Alegre J. M., Pinto F. L., O'Sullivan S. N., Antona F. B., Jimenez B. M., Lopez-Sanchez J., Carmona Z. G., Fernandez R. T., Sierra I. B., de Leon L. R. G., Moreno V. P., Iglesias E., Cumplido P. L., Bravo A. A., Simo I. R., Dominguez C. L., Caamano A. G., Lozano R. C., Martinez M. D., Torres A. N., de Quiros J. T. M. B., Pellino G., Cloquell M. M., Moller E. G., Jalal-Eldin S., Abdoun A. K., Hamid H. K. S., Lohsiriwat V., Mongkhonsupphawan A., Baraket O., Ayed K., Abbassi I., Ali A. B., Ammar H., Kchaou A., Tlili A., Zribi I., Colak E., Polat S., Koylu Z. A., Guner A., Usta M. A., Reis M. E., Mantoglu B., Gonullu E., Akin E., Altintoprak F., Bayhan Z., Firat N., Isik A., Memis U., Bayrak M., Altintas Y., Kara Y., Bozkurt M. A., Kocatas A., Das K., Seker A., Ozer N., Atici S. D., Tuncer K., Kaya T., Ozkan Z., Ilhan O., Agackiran I., Uzunoglu M. Y., Demirbas E., Altinel Y., Meric S., Hacim N. A., Uymaz D. S., Omarov N., Balik E., Tebala G. D., Khalil H., Rana M., Khan M., Florence C., Swaminathan C., Leo C. A., Liasis L., Watfah J., Trostchansky I., Delgado E., Pontillo M., Latifi R., Coimbra R., Edwards S., Lopez A., Velmahos G., Dorken A., Gebran A., Palmer A., Oury J., Bardes J. M., Seng S. S., Coffua L. S., Ratnasekera A., Egodage T., Echeverria-Rosario K., Armento I., Napolitano L. M., Sangji N. F., Hemmila M., Quick J. A., Austin T. R., Hyman T. S., Curtiss W., McClure A., Cairl N., Biffl W. L., Truong H. P., Schaffer K., Reames S., Banchini F., Capelli P., Coccolini F., Sartelli M., Bravi F., Vallicelli C., Agnoletti V., Baiocchi G. L., Catena F., Perrone, G, Giuffrida, M, Abu-Zidan, F, Kruger, V, Livrini, M, Petracca, G, Rossi, G, Tarasconi, A, Tian, B, Bonati, E, Mentz, R, Mazzini, F, Campana, J, Gasser, E, Kafka-Ritsch, R, Felsenreich, D, Dawoud, C, Riss, S, Gomes, C, Gomes, F, Gonzaga, R, Canton, C, Pereira, B, Fraga, G, Zem, L, Cordeiro-Fonseca, V, de Mesquita Tauil, R, Atanasov, B, Belev, N, Kovachev, N, Melendez, L, Dimova, A, Dimov, S, Zelic, Z, Augustin, G, Bogdanic, B, Moric, T, Chouillard, E, Bajul, M, De Simone, B, Panis, Y, Esposito, F, Notarnicola, M, Lauka, L, Fabbri, A, Hentati, H, Fnaiech, I, Aurelien, V, Bougard, M, Roulet, M, Demetrashvili, Z, Pipia, I, Merabishvili, G, Bouliaris, K, Koukoulis, G, Doudakmanis, C, Xenaki, S, Chrysos, E, Kokkinakis, S, Vassiliu, P, Michalopoulos, N, Margaris, I, Kechagias, A, Avgerinos, K, Katunin, J, Lostoridis, E, Nagorni, E, Pujante, A, Mulita, F, Maroulis, I, Vailas, M, Marinis, A, Siannis, I, Bourbouteli, E, Manatakis, D, Tasis, N, Acheimastos, V, Maria, S, Stylianos, K, Kuzeridis, H, Korkolis, D, Fradelos, E, Kavalieratos, G, Petropoulou, T, Polydorou, A, Papacostantinou, I, Triantafyllou, T, Kimpizi, D, Theodorou, D, Toutouzas, K, Chamzin, A, Frountzas, M, Schizas, D, Karavokyros, I, Syllaios, A, Charalabopoulos, A, Boura, M, Baili, E, Ioannidis, O, Loutzidou, L, Anestiadou, E, Tsouknidas, I, Petrakis, G, Polenta, E, Bains, L, Gupta, R, Singh, S, Khanduri, A, Bala, M, Kedar, A, Pisano, M, Podda, M, Pisanu, A, Martines, G, Trigiante, G, Lantone, G, Agrusa, A, Di Buono, G, Buscemi, S, Veroux, M, Gioco, R, Veroux, G, Oragano, L, Zonta, S, Lovisetto, F, Feo, C, Pesce, A, Fabbri, N, Marino, F, Perrone, F, Vincenti, L, Papagni, V, Picciariello, A, Rossi, S, Picardi, B, Del Monte, S, Visconti, D, Osella, G, Petruzzelli, L, Pignata, G, Andreuccetti, J, D'Alessio, R, Buonfantino, M, Guaitoli, E, Spinelli, S, Sampietro, G, Corbellini, C, Lorusso, L, Frontali, A, Pezzoli, I, Bonomi, A, Chierici, A, Cotsoglou, C, Manca, G, Delvecchio, A, Musa, N, 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F., Livrini M., Petracca G. L., Rossi G., Tarasconi A., Tian B. W. C. A., Bonati E., Mentz R., Mazzini F. N., Campana J. P., Gasser E., Kafka-Ritsch R., Felsenreich D. M., Dawoud C., Riss S., Gomes C. A., Gomes F. C., Gonzaga R. A. T., Canton C. A. B., Pereira B. M., Fraga G. P., Zem L. G., Cordeiro-Fonseca V., de Mesquita Tauil R., Atanasov B., Belev N., Kovachev N., Melendez L. J. J., Dimova A., Dimov S., Zelic Z., Augustin G., Bogdanic B., Moric T., Chouillard E., Bajul M., De Simone B., Panis Y., Esposito F., Notarnicola M., Lauka L., Fabbri A., Hentati H., Fnaiech I., Aurelien V., Bougard M., Roulet M., Demetrashvili Z., Pipia I., Merabishvili G., Bouliaris K., Koukoulis G., Doudakmanis C., Xenaki S., Chrysos E., Kokkinakis S., Vassiliu P., Michalopoulos N., Margaris I., Kechagias A., Avgerinos K., Katunin J., Lostoridis E., Nagorni E. -A., Pujante A., Mulita F., Maroulis I., Vailas M., Marinis A., Siannis I., Bourbouteli E., Manatakis D. K., Tasis N., Acheimastos V., Maria S., Stylianos K., Kuzeridis H., Korkolis D., Fradelos E., Kavalieratos G., Petropoulou T., Polydorou A., Papacostantinou I., Triantafyllou T., Kimpizi D., Theodorou D., Toutouzas K., Chamzin A., Frountzas M., Schizas D., Karavokyros I., Syllaios A., Charalabopoulos A., Boura M., Baili E., Ioannidis O., Loutzidou L., Anestiadou E., Tsouknidas I., Petrakis G., Polenta E., Bains L., Gupta R., Singh S. K., Khanduri A., Bala M., Kedar A., Pisano M., Podda M., Pisanu A., Martines G., Trigiante G., Lantone G., Agrusa A., Di Buono G., Buscemi S., Veroux M., Gioco R., Veroux G., Oragano L., Zonta S., Lovisetto F., Feo C. V., Pesce A., Fabbri N., Marino F., Perrone F., Vincenti L., Papagni V., Picciariello A., Rossi S., Picardi B., Del Monte S. R., Visconti D., Osella G., Petruzzelli L., Pignata G., Andreuccetti J., D'Alessio R., Buonfantino M., Guaitoli E., Spinelli S., Sampietro G. M., Corbellini C., Lorusso L., Frontali A., Pezzoli I., Bonomi A., Chierici A., Cotsoglou C., Manca G., Delvecchio A., Musa N., Casati M., Letizia L., Abate E., Ercolani G., D'Acapito F., Solaini L., Guercioni G., Cicconi S., Sasia D., Borghi F., Giraudo G., Sena G., Castaldo P., Cardamone E., Portale G., Zuin M., Spolverato Y., Esposito M., Isernia R. M., Di Salvo M., Manunza R., Esposito G., Agus M., Asti E. L. G., Bernardi D. T., Tonucci T. P., Luppi D., Casadei M., Bonilauri S., Pezzolla A., Panebianco A., Laforgia R., De Luca M., Zese M., Parini D., Jovine E., De Sario G., Lombardi R., Aprea G., Palomba G., Capuano M., Argenio G., Orio G., Armellino M. F., Troian M., Guerra M., Nagliati C., Biloslavo A., Germani P., Aizza G., Monsellato I., Chahrour A. C., Anania G., Bombardini C., Bagolini F., Sganga G., Fransvea P., Bianchi V., Boati P., Ferrara F., Palmieri F., Cianci P., Gattulli D., Restini E., Cillara N., Cannavera A., Nita G. E., Sarnari J., Roscio F., Clerici F., Scandroglio I., Berti S., Cadeo A., Filippelli A., Conti L., Grassi C., Cattaneo G. M., Pighin M., Papis D., Gambino G., Bertino V., Schifano D., Prando D., Fogato L., Cavallo F., Ansaloni L., Picheo R., Pontarolo N., Depalma N., Spampinato M., D'Ugo S., Lepre L., Capponi M. G., Campa R. D., Sarro G., Dinuzzi V. P., Olmi S., Uccelli M., Ferrari D., Inama M., Moretto G., Fontana M., Favi F., Picariello E., Rampini A., Barberis A., Azzinnaro A., Oliva A., Totaro L., Benzoni I., Ranieri V., Capolupo G. T., Carannante F., Caricato M., Ronconi M., Casiraghi S., Casole G., Pantalone D., Alemanno G., Scheiterle M., Ceresoli M., Cereda M., Fumagalli C., Zanzi F., Bolzon S., Guerra E., Lecchi F., Cellerino P., Ardito A., Scaramuzzo R., Balla A., Lepiane P., Tartaglia N., Ambrosi A., Pavone G., Palini G. M., Veneroni S., Garulli G., Ricci C., Torre B., Russo I. S., Rottoli M., Tanzanu M., Belvedere A., Milone M., Manigrasso M., De Palma G. D., Piccoli M., Pattacini G. C., Magnone S., Bertoli P., Massucco P., Palisi M., Luzzi A. -P., Fleres F., Clarizia G., Spolini A., Kobe Y., Toma T., Shimamura F., Parker R., Ranketi S., Mitei M., Svagzdys S., Pauzas H., Zilinskas J., Poskus T., Kryzauskas M., Jakubauskas M., Zakaria A. D., Zakaria Z., Wong M. P. -K., Jusoh A. C., Zakaria M. N., Cruz D. R., Elizalde A. B. R., Reynaud A. B., Hernandez E. E. L., Monroy J. M. V. P., Hinojosa-Ugarte D., Quiodettis M., Du Bois M. E., Latorraca J., Major P., Pedziwiatr M., Pisarska-Adamczyk M., Waledziak M., Kwiatkowski A., Czyzykowski L., da Costa S. D., Pereira B., Ferreira A. R. O., Almeida F., Rocha R., Carneiro C., Perez D. P., Carvas J., Rocha C., Ferreira C., Marques R., Fernandes U., Leao P., Goulart A., Pereira R. G., Patrocinio S. D. D., de Mendonca N. G. G., Manso M. I. C., Morais H. M. C., Cardoso P. S., Calu V., Miron A., Toma E. A., Gachabayov M., Abdullaev A., Litvin A., Nechay T., Tyagunov A., Yuldashev A., Bradley A., Wilson M., Panyko A., Lateckova Z., Lacko V., Lesko D., Soltes M., Radonak J., Turrado-Rodriguez V., Termes-Serra R., Morales-Sevillano X., Lapolla P., Mingoli A., Brachini G., Degiuli M., Sofia S., Reddavid R., de Manzoni Garberini A., Buffone A., del Pozo E. P., Aparicio-Sanchez D., Dos Barbeito S., Estaire-Gomez M., Viton-Herrero R., de los Angeles Gil Olarte-Marquez M. a., Gil-Martinez J., Alconchel F., Nicolas-Lopez T., Rahy-Martin A. C., Pelloni M., Banolas-Suarez R., Mendoza-Moreno F., Nisa F. G. -M., Diez-Alonso M., Rodas M. E. V., Agundez M. C., Andres M. I. P., Moreira C. C. L., Perez A. L., Ponce I. A., Gonzalez-Castillo A. M., Membrilla-Fernandez E., Salvans S., Serradilla-Martin M., Pardo P. S., Rivera-Alonso D., Dziakova J., Huguet J. M., Valle N. P., Ruiz E. C., Valcarcel C. R., Moreno C. R., Salazar Y. T. M., Garcia J. J. R., Mico S. S., Lopez J. R., Farre S. P., Gomez M. 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E., Mantoglu B., Gonullu E., Akin E., Altintoprak F., Bayhan Z., Firat N., Isik A., Memis U., Bayrak M., Altintas Y., Kara Y., Bozkurt M. A., Kocatas A., Das K., Seker A., Ozer N., Atici S. D., Tuncer K., Kaya T., Ozkan Z., Ilhan O., Agackiran I., Uzunoglu M. Y., Demirbas E., Altinel Y., Meric S., Hacim N. A., Uymaz D. S., Omarov N., Balik E., Tebala G. D., Khalil H., Rana M., Khan M., Florence C., Swaminathan C., Leo C. A., Liasis L., Watfah J., Trostchansky I., Delgado E., Pontillo M., Latifi R., Coimbra R., Edwards S., Lopez A., Velmahos G., Dorken A., Gebran A., Palmer A., Oury J., Bardes J. M., Seng S. S., Coffua L. S., Ratnasekera A., Egodage T., Echeverria-Rosario K., Armento I., Napolitano L. M., Sangji N. F., Hemmila M., Quick J. A., Austin T. R., Hyman T. S., Curtiss W., McClure A., Cairl N., Biffl W. L., Truong H. P., Schaffer K., Reames S., Banchini F., Capelli P., Coccolini F., Sartelli M., Bravi F., Vallicelli C., Agnoletti V., Baiocchi G. L., and Catena F.
- Abstract
Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. Methods: This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 patients with left-sided colonic emergencies who required surgery were included from 204 centers during the period of March 1, 2020, to May 31, 2020. with a 1-year follow-up. Results: 564 patients (43.1%) were females. The mean age was 65.9 ± 15.6 years. HP was performed in 697 (57.3%) patients and RPA in 384 (31.6%) cases. Complicated acute diverticulitis was the most common cause of left-sided colonic emergencies (40.2%), followed by colorectal malignancy (36.6%). Severe complications (Clavien-Dindo ≥ 3b) were higher in the HP group (P < 0.001). 30-day mortality was higher in HP patients (13.7%), especially in case of bowel perforation and diffused peritonitis. 1-year follow-up showed no differences on ostomy reversal rate between HP and RPA. (P = 0.127). A backward likelihood logistic regression model showed that RPA was preferred in younger patients, having low ASA score (≤ 3), in case of large bowel obstruction, absence of colonic ischemia, longer time from admission to surgery, operating early at the day working hours, by a surgeon who performed more than 50 colorectal resections. Conclusions: After 100 years since the first Hartmann’s procedure, HP remains the most common treatment for left-sided colorectal emergencies. Treatment’s choice depends on patient characteristics, the time of surgery and the experience of the surgeon. RPA should be considered as the gold standard for surgery, with HP being an exception.
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- 2024
6. Metabarcoding the Antarctic Peninsula biodiversity using a multi-gene approach
- Author
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Fonseca, V. G., Kirse, A., Giebner, H., Vause, B. J., Drago, T., Power, D. M., Peck, L. S., and Clark, M. S.
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- 2022
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7. POS1318 DYSREGULATION OF CIRCULATING T FOLLICULAR CELLS, BUT NOT B CELLS, IS ASSOCIATED WITH ANTIPHOSPHOLIPID ANTIBODIES POSITIVITY IN PATIENTS WITH THROMBOTIC PRIMARY ANTIPHOSPHOLIPID SYNDROME
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Gaspar, P., primary, Cruz-Machado, A. R., additional, Ribeiro, F., additional, Pascual-García, S., additional, Fonseca, V. R., additional, Romão, V. C, additional, and Graca, L., additional
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- 2024
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8. OP0229 ADJUSTED GLOBAL ANTIPHOSPHOLIPID SYNDROME SCORE (aGAPSS) AT DIAGNOSIS AND PERSISTENT ANTIPHOSPHOLIPID ANTIBODIES ARE STRONGER PREDICTORS OF RECURRENT THROMBOSIS IN PRIMARY ANTIPHOSPHOLIPID SYNDROME
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Gaspar, P., primary, Cruz-Machado, A. R., additional, Ribeiro, F., additional, Fonseca, V. R., additional, Sciascia, S., additional, Graca, L., additional, and Romão, V. C, additional
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- 2024
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9. Exploring the efficacy and challenges of Levodopa-Carbidopa Intestinal Gel in treating patients with Multiple System Atrophy: Experience of two centers
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Lopes, S., primary, Fonseca, V., additional, Simões, R., additional, Varanda, S., additional, Carneiro, G., additional, and Rodrigues, M., additional
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- 2024
- Full Text
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10. Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study
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Podda, M, Di Martino, M, Pata, F, Nigri, G, Pisanu, A, Di Saverio, S, Pellino, G, Ielpo, B, Null, N, Tolla, A, Abdelkhalek, M, Emile, S, Dinagde, T, Bouzid, C, Mansour, A, Garzali, I, Aregawi, A, Zaghloul, T, Kchaou, A, Awad, S, Souadka, A, Ted, T, Saumtally, M, Ahmed, B, Bayileyegn, N, Nunziante, M, Shalaby, M, Debena, D, Zena, A, Adewunmi, O, Negasa, T, Bourguiba, M, Feituri, N, Kebede, K, Elfeki, H, Anas, A, Awad, A, Ermias, N, Hailemariam, D, Bejiga, G, Imana, R, Taffese, A, Feleke, T, Elghadban, H, Debela, B, Shiferaw, D, Tadesse, R, Chukwu, I, Mohammed, A, Hassen, K, Obiagwu, N, Tense, T, Taeme, M, Biniam, E, Tesfay, G, Tegegn, A, Teddy, T, Bekana, B, Nidaw, M, Ali, M, Gonfa, K, Kiros, S, Belay, T, Yallew, G, Wassie, C, Ayalew, A, Asfaw, F, Aimal, A, Casas, M, Madrid, F, Diaz-Elizondo, J, Merlo, I, De Campos, T, Schlottmann, F, Gomes, C, Hernández, E, Moncada-Ortega, A, Ramos-De la Medina, A, Vanerio, P, Morales, E, Stringfield, S, Gallardo, C, Fonseca, V, Muriel, M, Cantarino, F, Fichera, A, Rodriguez, A, Salinas, R, Crosbie, G, Menegozzo, C, Avellaneda, N, Briones, C, Varela, C, Lichliter, W, Koppel, D, Lenz, J, Pascual, F, Sibaja-Matamoros, D, Johnson, B, Mercado, O, Tita, A, Mukherjee, I, Lorenzo, I, Rueda, E, Rico, D, Terwes, N, Visag-Castillo, V, Escalante, K, Salvador, A, Pio, L, Rodas, E, Aguilar, J, Neri, I, Barzola, E, Barba, L, Zuchini, A, Acevedo, A, Gachabayov, M, Gonsaga, R, Bonilla, F, Knickerbocker, C, Tsouknidas, I, Salamea, J, Travers, L, Nari, G, Pachajoa, D, Valadez, M, Hale, L, Perez, G, Choudhry, A, Foreman, M, Brito, I, Ciro, M, Newton, C, Souza, H, Davis, D, Ferreira, R, Keller, D, Miguel, G, Singh-Ranger, G, Linares, N, Singares, E, Valdivieso, X, Teran, A, Vargas, L, Valinoti, A, Milne, D, Fleming, A, Quiroga-Garza, A, Espino, E, Bedros, N, Funk, G, Neves, F, Supit, T, Baba, A, Chalkoo, M, Kucuk, G, Sarmiento, R, Galeev, S, Korkoman, M, Yang, W, Medappil, N, Athar, R, Subramaniam, R, Chia, C, Alhazmi, A, Halder, S, Rusli, S, Rashid, A, Gülcü, B, Nagarajan, P, Rida, K, Jamiri, A, Batıkan, O, Khan, H, Mitul, A, Efetov, S, Junior, M, Gulcu, B, Farooqui, M, Mulpuri, V, Bagaria, D, Yusoff, A, Wani, R, Younis, M, Khobragade, K, Marwat, M, Bains, L, Kobe, Y, Koh, P, Tantravahi, U, Mohamad Mohamad, I, Abu-Arish, H, Yildirim, A, Ibrahim, A, Tan, J, Siagian, D, Bhattacharya, N, Chiu, J, Paramasvaran, G, Voon, K, Göktepe, B, Lee, L, Gupta, A, Rasheed, F, Al-Shehari, M, Syed, S, Bhat, P, Erdoğan, E, Roat, R, Nacion, A, Saraiya, S, Afolabi, A, Chai, F, Ghannam, W, Bhattacharya, K, Nl, H, Aloun, A, Bhatti, H, Koneti, A, Klib, M, Qureshi, A, Syn, N, Wani, A, Saeidi, S, Zeb, M, Bandaru, K, Menna, M, Morales-Conde, S, Gessa, E, Sánchez-Cabús, S, Spartalis, E, Antropoli, C, Manigrasso, M, Sica, G, Ercolani, G, Chitul, A, Bacchiocchi, G, Azevedo, J, Karamarkovic, A, Bonavina, L, Piozzi, G, Migueláñez, I, Merlini, D, Major, P, Grimaldi, L, Calu, V, Curro, G, Cotsoglou, C, Baldini, E, Delis, S, Kovacevic, B, Masetti, M, Selvaggi, F, Scabini, S, Reiti, A, Zullo, A, Giuliani, A, Alesina, P, Massey, L, Slesser, A, Neary, P, Sahnan, K, Colucci, G, Brady, R, Mihailescu, A, Adamina, M, Gerogiannis, I, van Ramshorst, G, Paradiso, G, Poto, G, Massaro, D, Nazir, F, Stubbs, B, Tasselli, F, Muñoz-Cruzado, V, Sabia, D, Vannelli, A, Marsella, V, Tomada, E, Giambusso, M, Davies, J, Uzzau, A, Balla, A, Scaringi, S, Lancellotti, F, Douka, E, Argenio, G, Cassese, G, Ammendola, M, Morelli, L, Francone, E, Bala, M, Thambi, P, Iacobone, M, Campisi, A, Tejedor, P, Spoletini, G, Mascherini, M, Belia, F, Idiz, U, Colak, E, Peters, P, Ros, E, Aytac, E, Vilallonga, R, Serrablo, A, Muttillo, E, Di Franco, G, Vanni, G, Isik, A, Sbacco, V, Tropeano, F, Porcellini, I, Butler, R, Fernandez, C, Papadopoulos, A, Salvans, S, Khan, J, Bellver, P, Mc Farlane, S, Apostolou, K, Tur-Martinez, J, Castellano, J, Santoliquido, M, Tallon-Aguilar, L, Celentano, V, Aliyev, V, al-Najami, I, Grama, F, Masior, Ł, Ciesielski, W, Luberto, A, Sparavigna, M, Klimczak, T, Negoi, I, Serradilla-Martín, M, Marinis, A, Cammarat, R, Bellido-luque, J, Manzo, C, Milana, F, Luglio, G, Zarnescu, N, Martínez, I, Olmi, S, Costea, R, Cerdán-Santacruz, C, Gica, N, Rompianesi, G, Gallo, G, Ridolfi, C, Sahid, S, Cc, T, López-Soler, G, Díaz, C, Mccawley, N, Luzzi, A, Abelló, D, Bonito, A, Ntomi, V, Gourgiotis, S, Pazos, N, Toscano, M, Zafra, D, Beisani, M, Oliva, A, Guler, M, Gómez, M, Oddis, L, Montcusí, B, Delgado, A, Lasarte, M, Antonacci, N, Sartori, A, Taylor, J, de Santos Iglesias, F, Mastronardi, M, Gunay, E, Yiu, A, Cano-Valderrama, O, Costantini, G, Digne-Malcolm, H, Petropoulou, T, Horesh, N, Kelly, M, Ahmed, N, Wyroslak-Najs, J, Naik, P, Vigorita, V, Michael, M, Castro, E, Paspala, A, D'Ambrosio, M, Pangeni, A, Dziakova, J, Terés, L, Lorente-Poch, L, Di Carlo, I, Spartalis, M, Moro-Valdezate, D, Davey, M, Turrado-Rodriguez, V, Tryliskyy, Y, Calussi, M, Farré, S, Labat, M, Marafante, C, Takkenberg, M, Brookes, C, Soares, A, Gialamas, E, Caputo, D, Corrons, L, Capitano, S, Charalabopoulos, A, Don, C, Marrano, E, Giuffrida, M, Tomasicchio, G, Bellato, V, Stijns, J, Creavin, B, Schizas, D, Blanco-Antona, F, Kykalos, S, Tartaglia, N, Pelegrina, A, Barranquero, A, Schena, C, Cremona, S, Baili, E, Cianci, P, Di Bella, A, Forcignanò, E, Fabbrizio, T, Salvetti, F, Inama, M, Campagnaro, T, Deerenberg, E, Reccia, I, Rocca, A, Fazio, F, Tampakis, A, Tepelenis, K, Di Meo, G, Konstantoudakis, G, Manatakis, D, Mineccia, M, Delvecchio, A, Faro, C, Rosso, E, Bandyopadhyay, S, Queffurus, M, Marin, J, Corvasce, A, Chillarge, G, Mohammed, M, Reid, R, Gherardi, D, Naeem, A, Pandanaboyana, S, Tayeh, S, Chevallay, M, Sergeant, G, Cuccomarino, S, Salimian, N, Kapsampelis, P, Ferretti, C, Glasbey, J, Harvitkar, R, Iqbal, M, de Oliveira, G, Pérez-Bertólez, S, Bergna, A, Brisinda, G, Rottoli, M, Roscio, F, Pedrazzani, C, Meyer, J, Marino, M, Brasset, C, Daniel, C, Devriendt, S, Soldini, G, Pennisi, D, Richards, C, Fiore, F, Bocchino, A, Au, S, Hernandez-Garcia, M, Frontali, A, Grossi, U, Lolis, E, Miotto, M, Di Filippo, G, Seretis, C, Barberis, A, De Luca, R, Levi Sandri, G, Reitano, E, Mattioli, M, Sciaudone, G, Fuschillo, G, Schiltz, B, Low, J, Bointas, G, Cozza, V, Delaune, V, Vescio, F, Curcio, S, Sevik, H, Santocchi, P, Stecca, T, Balaphas, A, Chessa, A, Leo, C, di Mola, F, Tarallo, M, Martini, F, Lisi, G, Khan, M, Nicolazzi, M, Pinotti, E, Morini, A, Esposito, G, Buonomo, O, Corallino, D, Demir, A, Roesel, R, De Lucia, C, Maruccia, M, Tekin, O, Pavone, G, Pradelle, I, Chrysikos, M, Farrukh, M, Baiocchi, G, Piras, C, Abellán, A, Olivieri, L, Materazzo, M, Carbone, L, Dulskas, A, Mulita, F, Corronca, F, Cappuccio, M, Smerieri, E, Sotiropoulu, M, Violante, T, Moletta, L, Rutegård, M, Brillantino, A, Landaluce-Olavarria, A, Ossola, P, Bono, D, Rosés, H, Perez-Sanchez, L, Sabbatini, S, Scotti, M, Cammarata, R, Ibáñez, N, Marano, A, Palmisano, S, Cascales-Sanchez, P, Mosca, V, Ballester, C, Iordache-Petrescu, M, Pozza, G, Akay, O, Bollino, R, Toti, J, Mascianà, G, Pach, R, Sensi, B, Natalia, S, Coppola, A, Altinel, Y, Brucchi, F, Guitart, M, Salido, A, Tamini, N, Garoufalia, Z, Mifsut, P, Wilkins, A, Navarro-Sánchez, A, Cestaro, G, Conti, L, Carvas, J, Gazia, C, Alonso, P, Spiezio, G, Maggi, G, Juloski, J, Braccio, B, Pañella, C, Freixa, C, Petrakis, G, Folliero, C, De Andrés-Asenjo, B, Iodice, A, Jansson, H, González, T, Ortega, I, Castro, M, Fernicola, A, Aparicio, A, Ortega, N, Chouliaras, C, Tura, M, Sidiropoulou, Z, Gonzalez, A, Augustin, G, Segura-Sampedro, J, Cuk, V, Piccolo, G, Ingallinella, S, Ortenzi, M, Uggeri, F, Carrabetta, S, Tolonen, M, Formisano, G, Manfredelli, S, Perra, T, Esposito, F, Perrone, G, Zacharis, G, Menéndez, J, Bottcher, S, Ioannidis, O, Borges, N, Sousa, X, Colombari, R, Tellez, C, Capolupo, G, Giuliani, G, Mastella, F, González, L, Merlini, I, Ghignone, F, de Sa, T, Mangana, O, Rodriguez-Lopez, M, Alvarez-Gallego, M, Chowdhury, A, Di Lascio, P, Carneros, V, Angrisani, M, Conte, L, Montiel, C, Ascari, F, Dajti, I, Lapolla, P, Sperotto, B, Mazzarella, G, Capuano, M, Lopez, M, Ferrario, L, Bulte, J, López, M, Guerci, C, Marra, A, Belkacem, A, Pérez, R, Panyko, A, Dimitrov, E, Luque, E, Manrique, M, Paranyak, M, Kaur, M, Barugola, G, Farazi-Chongouki, C, Estaire-Gómez, M, del Olmo, J, Nardo, B, Mutlu, A, Rubio, A, Marchegiani, F, Cereda, M, Vinci, D, Komaei, I, Petrucciani, N, Seyfried, S, Krsicka, P, Medas, F, Lesko, D, Murzi, V, Siragusa, L, Guerrero, M, Iranzo, M, Cestino, L, Pasculli, A, Smerieri, N, Benzoni, I, Festa, F, Jordão, D, Licardie, E, Nicolaescu, D, Balassone, V, La Vaccara, V, Romano, F, Adamovich, D, Papatheodorou, P, Maroni, N, Colás-Ruiz, E, Melberga, L, Chimenti, F, Ferrari, D, Arcudi, C, Police, A, De Simone, B, Sánchez-Guillén, L, Parreño-Manchado, F, Rachadell, J, Coletta, D, Saroglu, A, Pattacini, G, Antonelli, A, Anania, M, Litta, F, Lafranceschina, S, Bottari, A, Pavlovic, M, Rojas-Bonet, N, Tampaki, E, Kosir, J, Anelli, F, de las Casas, S, Kucukarslan, R, Pierobon, E, Milanesi, M, Drogouti, M, Sotiropoulou, M, Di Marco, F, Bannone, E, Sliwinski, S, Yildiz, I, Pellicciaro, M, Celotti, A, Malerba, M, Marino, F, Bourmpouteli, E, Bianco, G, Charitaki, E, Pascale, M, Ioannidis, A, Maraska, F, Petagna, L, Turri, G, Vailas, M, Romanzi, A, Pouwels, S, Rosa, F, Clocchiatti, L, Andreuccetti, J, Machairas, N, Frountzas, M, Lasithiotakis, K, Barone, M, Christodoulou, P, Potkonjak, D, Aiolfi, A, de Vries, H, Napetti, S, Castaldi, A, Botelho, P, Marziali, I, Uccelli, M, Pisano, M, Veroux, M, Locci, E, Romano, A, Cero, M, Cicerchia, P, Baldi, C, Russo, I, Tenconi, S, Saliu, F, Bondurri, A, Cardinali, L, Laracca, G, Martín-Pérez, B, Felsenreich, D, Cunha, M, Zerbo, D, Clementi, M, Delogu, D, Iossa, A, Bavikatte, A, Saracoglu, C, Pecorelli, N, Tufo, A, Biloslavo, A, Lianos, G, Carannante, F, Costanzo, A, Montuori, M, Cigognini, M, Silvestro, R, Atici, S, Milito, P, Ferronetti, A, Güngör, M, Di Venere, B, Puccioni, C, De Nobili, G, Selvaggi, L, Farolfi, T, Aeschbacher, P, Olivier, J, Frazzetta, G, Andriola, V, Giordano, A, De Luca, A, Ferrara, F, Casagranda, B, Sammartano, F, Russo, A, Rossi, S, Pacilli, M, Synekidou, E, Tutino, R, Ceresoli, M, De Rosa, M, Di Santo Albini, A, Vincenzi, P, Vellei, S, Benzoni, E, Murillo, G, Izzo, G, Scotto, B, Caruso, R, Colombo, F, D'Acapito, F, Lostoridis, E, Saladino, E, Poillucci, G, Moeckli, B, Manto, O, Kara, Y, Tatar, C, Cioffi, S, Mambrilla, S, Bianchi, V, Scopelliti, M, Agresta, F, Nava, A, Franchi, E, Fransvea, P, Prieto, M, Picardi, B, Rizzuto, A, Panaccio, P, Gussago, S, Marra, E, Addeo, P, Fernández Fernández, J, Gulmez, M, Pisaniello, D, Cannavo, M, López-López, V, Avella, P, Peloso, A, Bellanova, G, Candilio, G, Perotti, B, Granata, R, Florio, G, Ioia, G, Iannone, I, Ammerata, G, Zambon, M, Del Monte, S, Sasia, D, Fortuna, L, Litvin, A, Cannistra, M, De Padua, C, Sánchez, T, Paniagua-Garcia-Señorans, M, Guevara, J, Perfecto, A, Alconchel, F, Campanelli, M, Keci, L, Cricrì, M, Kampouroglou, G, Bagaglini, G, Farrarons, S, Greco, A, Walędziak, M, Serrano-Navidad, M, Van Doorn, B, Schiavo, C, Fabbri, N, Wani, I, Mondi, I, Anestiadou, E, Mendes, B, Verdi, D, Dorovinis, P, Cacciaguerra, A, Caldeira, B, Canonico, G, Dardanov, D, D'Ugo, S, Francis, F, Meneghini, S, Pesce, A, Puglisi, S, Bellini, M, Giordano, M, Fleres, F, Campus, F, Cillara, N, Moggia, E, Ciarleglio, F, Calini, G, Gravante, G, De Carlis, R, Altomare, M, Martines, G, Miggino, M, Marano, L, Stocco, A, Porcu, A, Pham, T, Gervasi, M, Pilia, T, Palomba, G, Picchetto, A, Spampinato, M, Tandoi, F, Piccoli, M, Gall, M, Santos, B, Agastra, E, Koëter, T, Samadov, E, Marsanic, P, Serena, D, Uzunoglu, M, Zanus, G, Braholli, E, Giovine, G, Galiffa, G, Lauricella, S, Lukmonov, S, Leventoglu, S, Chooklin, S, Dudi-Venkata, N, Gauci, C, Podda, Mauro, Di Martino, Marcello, Pata, Francesco, Nigri, Giuseppe, Pisanu, Adolfo, Di Saverio, Salomone, Pellino, Gianluca, Ielpo, Benedetto, null, null, Tolla, Ashenafi Negash, Abdelkhalek, Mohamed, Emile, Sameh, Dinagde, Tesfaye Aga, Bouzid, Chafik, Mansour, Ahmed Mohammed Farid Mahmoud, Garzali, Ibrahim Umar, Aregawi, Alazar Berhe, Zaghloul, Tarek M., Kchaou, Ali, Awad, Selmy S., Souadka, Amine, Ted, Tedla Gebretsadik, Saumtally, Mohammad Saad, Ahmed, Bensaad, Bayileyegn, Nebiyou Simegnew, Nunziante, Marco, Shalaby, Mostafa, Debena, Dawit Gebregiorgis, Zena, Alemayehu Shanko, Adewunmi, Olayinka Lukman, Negasa, Tolera A., Bourguiba, Mohamed Aboulkacem, Feituri, Nura, Kebede, Kirubel Abebe, Elfeki, Hossam, Anas, Abdelhmed, Awad, Ahmed K., Ermias, Nebiyou, Hailemariam, Dagnachew H., Bejiga, Gosa Hundie, Imana, Ruhama Yoseph, Taffese, Abebe, Feleke, Tsega Terefe, Elghadban, Hosam Mohamed, Debela, Bizuneh Sime, Shiferaw, Desta, Tadesse, Robel, Chukwu, Isaac Sunday, Mohammed, Abdullahi Ibrahim, Hassen, Khalid Arebo, Obiagwu, Ndubuisi K., Tense, Tadesse H., Taeme, Mulugeta, Biniam, Ewnte, Tesfay, Goytom Knfe, Tegegn, Ayenachew Getachew, Teddy, Tewodros Abule Bilata, Bekana, Bekana L., Nidaw, Melkamu Kibret, Ali, Mahmoud Ibrahim, Gonfa, Kebebe Bekele, Kiros, Samuel, Belay, Tatek, Yallew, Gebeyaw Mengist, Wassie, Chekol, Ayalew, Alem Mekete, Asfaw, Fitsum Terefe, Aimal, Aimal Khan, Casas, Maria Agustina, Madrid, Fausto A., Diaz-Elizondo, Jose Antonio, Merlo, Ignacio Guillermo, De Campos, Tercio, Schlottmann, Francisco, Gomes, Carlos Augusto, Hernández, Edgard Efrén Lozada, Moncada-Ortega, Augusto, Ramos-De la Medina, Antonio, Vanerio, Patricio, Morales, Emilio J., Stringfield, Sarah Beth, Gallardo, Cristian, Fonseca, Vinicius Cordeiro, Muriel, Maria Emilia, Cantarino, Frederico, Fichera, Alessandro, Rodriguez, Agustin E., Salinas, Roberto Paúl Andrade, Crosbie, Gonzalo Gabriel, Menegozzo, Carlos Augusto Metidieri, Avellaneda, Nicolas, Briones, Cristhian Gonzalo Aspiazu, Varela, Cristopher, Lichliter, Warren E., Varela, Cristopher L., Koppel, Darren, Lenz, Jorge Godoy, Pascual, Franco, Sibaja-Matamoros, Dauber A., Johnson, Benjamin E., Mercado, Octavio Avila, Tita, Agustín, Mukherjee, Indraneil, Lorenzo, Irving, Rueda, Erick, Rico, Douglas, Terwes, Natasha Loria, Visag-Castillo, Victor, Escalante, Karol S., Salvador, Alan Francisco Alfaro, Pio, Luca, Rodas, Edgar B., Aguilar, Juan Carlos Cardozo, Neri, Ignacio, Barzola, Ernesto J., Barba, Leonardo A., Zuchini, Andrés Mendoza, Acevedo, Ana Karen Radilla, Gachabayov, Mahir, Gonsaga, Ricardo Alessandro Teixeira, Bonilla, Fernando, Knickerbocker, Chase Barrett, Tsouknidas, Ioannis, Salamea, Juan C., Travers, Lawrence Albert Salter, Nari, Gustavo Adrian, Pachajoa, Diana Alejandra Pantoja, Valadez, Michel Hernandez, Hale, Lyman Lansing, Perez, Guillermo, Choudhry, Asad, Foreman, Michaael L., Brito, Ismael, Ciro, Mauricio Pedraza, Newton, Carla Joyce, Souza, Hamilton Petry, Davis, Daniel G., Ferreira, Rodrigo Vaz, Keller, Deborah S., Miguel, Gustavo Machain, Singh-Ranger, Gurpreet, Linares, Neiling Massiel Oviedo, Singares, Eduardo Smith, Valdivieso, Xavier HGarcía, Teran, Alfonso Ivan Sanchez, Vargas, Luis Felipe Cabrera, Valinoti, Agustín, Milne, David M., Fleming, Andrew Martin, Quiroga-Garza, Alejandro, Espino, Eduardo Morales, Bedros, Nicole Mary, Funk, Geoffrey A., Neves, Fernanda V. S., Supit, Tommy, Baba, Arshad Ahmed, Chalkoo, Mushtaq A., Kucuk, Gultekin Ozan, Sarmiento, Ray Inocencio, Galeev, Shamil I., Korkoman, Mohammed J., Yang, Wah, Medappil, Noushif, Athar, Rahmatullah, Subramaniam, Ravichandran, Chia, Chi Fung, Alhazmi, Ahmad, Halder, Subhadip, Rusli, Siti Mayuha, Rashid, Arshad, Gülcü, Barış, Nagarajan, Prasanth, Rida, Khaled, Jamiri, Al-Radjid, Batıkan, Oğuzkağan, Khan, Huma Ahmed, Mitul, Ashrarur Rahman, Efetov, Sergey, Junior, Marcelo A. F. Ribeiro, Gulcu, Baris, Farooqui, Marryam Riaz, Mulpuri, Venu Bhargava, Bagaria, Dinesh, Yusoff, Ahmad Ramzi, Wani, Rauf, Younis, Muhammad Umar, Khobragade, Krunal H., Marwat, Muhammad Ibrahim, Bains, Lovenish, Kobe, Yoshiro, Koh, Peng Soon, Tantravahi, Umasankar, Mohamad Mohamad, Ikhwan Sani, Abu-Arish, Hamdoon, Yildirim, Ali Cihat, Ibrahim, Aini Fahriza, Tan, Jih Huei, Siagian, Dumaria Ketty, Bhattacharya, Neela, Chiu, Jennifer H. F., Paramasvaran, Ganendra, Voon, Kelvin, Göktepe, Berk, Lee, Lee Yeong Sing, Gupta, Amit, Rasheed, Faaiz, Al-Shehari, Mohammed, Syed, Syed Muhammad Ali, Bhat, Pawan Singh, Erdoğan, Emre, Roat, Rajesh, Nacion, Aeris Jane D., Saraiya, Swapnil Mukesh, Afolabi, Akinwale Ibrahim, Chai, Feng Yih, Ghannam, Wagih, Bhattacharya, Kaushik, NL, Harish, Aloun, Ali, Bhatti, Hamza Waqar, Koneti, Akshadhar J., Klib, Mohamad, Qureshi, Ahmad Uzair, Syn, Nicholas L., Wani, Ajaz, Saeidi, Sara, Zeb, Muhammad, Bandaru, Kalyan Vijay Kumar, Menna, Maria Paola, Morales-Conde, Salvador, Gessa, Emanuela, Sánchez-Cabús, Santiago, Spartalis, Eleftherios, Antropoli, Carmine, Manigrasso, Michele, Sica, Giuseppe S., Ercolani, Giorgio, Chitul, Andrei, Bacchiocchi, Giulia, Azevedo, José, Karamarkovic, Aleksandar, Bonavina, Luigi, Piozzi, Guglielmo N., Migueláñez, Isabel Pascual, Merlini, David, Major, Piotr, Grimaldi, Luciano, Calu, Valentin, Curro, Giuseppe, Cotsoglou, Christian, Baldini, Edoardo, Delis, Spiros, Kovacevic, Bojan, Masetti, Michele, Selvaggi, Francesco, Scabini, Stefano, Reiti, Andrian, Zullo, Alessia, Giuliani, Antonio, Alesina, Pier Francesco, Massey, Lisa H., Slesser, Alistair A. P., Neary, Peter M., Sahnan, Kapil, Tan, Jessica J., Colucci, Gianluca, Brady, Richard R. W., Mihailescu, Andrei, Adamina, Michel, Gerogiannis, Ioannis, van Ramshorst, Gabrielle, Paradiso, Giulia, Poto, Gianmario Edoardo, Massaro, Daniele, Nazir, Fozia, Stubbs, Benjamin M., Tasselli, Francesco Menegon, Muñoz-Cruzado, Virginia Durán, Sabia, Domenico, Vannelli, Alberto, Marsella, Valentina Enrica, Tomada, Elisa Paoluzzi, Giambusso, Mauro, Davies, Justin, Uzzau, Alessandro, Balla, Andrea, Scaringi, Stefano, Lancellotti, Francesco, Douka, Eleftheria, Argenio, Giulio, Cassese, Gianluca, Ammendola, Michele, Morelli, Luca, Francone, Elisa, Bala, Miklosh, Thambi, Prem, Iacobone, Maurizio, Campisi, Andrea, Tejedor, Patricia, Spoletini, Gabriele, Mascherini, Matteo, Belia, Francesco, Idiz, Ufuk Oguz, Colak, Elif, Peters, Paul Adewunmi, Ros, Emilio Peña, Aytac, Erman, Vilallonga, Ramon, Serrablo, Alejandro, Muttillo, Edoardo Maria, Di Franco, Gregorio, Vanni, Gianluca, Isik, Arda, Sbacco, Valentina, Tropeano, Francesca Paola, Porcellini, Iride, Butler, Rebecca Jayne, Fernandez, Carmen Cagigas, Papadopoulos, Aristeidis, Salvans, Silvia, Khan, Jan Sher, Bellver, Pedro Palazón, Mc Farlane, Sebastian Jeri, Apostolou, Konstantinos, Tur-Martinez, Jaume, Castellano, Javier Rivera, Santoliquido, Matteo, Tallon-Aguilar, Luis, Celentano, Valerio, Aliyev, Vusal, al-Najami, Issam, Grama, Florin A., Masior, Łukasz, Ciesielski, Wojciech J., Luberto, Antonio, Sparavigna, Marco, Klimczak, Tomasz Jerzy, Negoi, Ionut, Serradilla-Martín, Mario, Marinis, Athanasios, Cammarat, Roberto, Bellido-luque, Juan, Manzo, Carlo Alberto, Milana, Flavio, Luglio, Gaetano, Zarnescu, Narcis Octavian, Martínez, Isidro, Olmi, Stefano, Costea, Radu V., Cerdán-Santacruz, Carlos, Gica, Nicolae, Rompianesi, Gianluca, Gallo, Gaetano, Ridolfi, Cristina, Sahid, Saidah, CC, Tommaso, López-Soler, Guillermo, Díaz, Carlos JGómez, Mccawley, Niamh, Luzzi, Andrea Pierre, Abelló, David, Bonito, Alba Correa, Ntomi, Vasileia, Gourgiotis, Stavros, Pazos, Natalia Suárez, Toscano, Marta Jiménez, Zafra, David Ambrona, Beisani, Marc, Oliva, Alba, Guler, Mert, Gómez, Marta Jiménez, Oddis, Lidia, Montcusí, Blanca, Delgado, Ander Timoteo, Lasarte, Mateusz PJęckowski Aingeru Sarriuga, Antonacci, Nicola, Sartori, Alberto, Taylor, John Vincent, de Santos Iglesias, Francisco Juan, Mastronardi, Manuela, Gunay, Emre, Yiu, Andrew, Cano-Valderrama, Oscar, Costantini, Giulia, Digne-Malcolm, Holly Jane, Petropoulou, Thalia, Horesh, Nir, Kelly, Michael E., Ahmed, Nauman, Wyroslak-Najs, Justyna, Naik, Prashant, Vigorita, Vincenzo, Michael, Michael, Castro, Ernest, Paspala, Anna, D'Ambrosio, Marco, Pangeni, Anang, Dziakova, Jana, Terés, Lara Blanco, Lorente-Poch, Leyre, Di Carlo, Isidoro, Spartalis, Michael, Moro-Valdezate, David, Davey, Matthew G., Turrado-Rodriguez, Victor, Tryliskyy, Yegor, Calussi, Marco, Farré, Silvia Pérez, Labat, Miriam Cazador, Marafante, Chiara, Takkenberg, Marijn, Brookes, Charlotte Elisabeth, Soares, Antonio S., Gialamas, Eleftherios, Caputo, Damiano, Corrons, Laia Codina, Capitano, Sante, Charalabopoulos, Alexandros, Don, Cristine Brooke Pathirannehalage, Marrano, Enrico, Giuffrida, Maria Carmela, Tomasicchio, Giovanni, Bellato, Vittoria, Stijns, Jasper, Creavin, Ben, Schizas, Dimitrios, Blanco-Antona, Francisco, Kykalos, Stylianos, Tartaglia, Nicola, Pelegrina, Amalia, Barranquero, Alberto G., Schena, Carlo Alberto, Cremona, Simone, Baili, Efstratia, Cianci, Pasquale, Di Bella, Annamaria, Forcignanò, Edoardo, Fabbrizio, Tiziana, Salvetti, Francesco, Inama, Marco, Campagnaro, Tommaso, Deerenberg, Eva B., Reccia, Isabella, Rocca, Aldo, Fazio, Federico, Tampakis, Athanasios, Tepelenis, Kostas, Di Meo, Giovanna, Konstantoudakis, Georgios, Manatakis, Dimitrios K., Mineccia, Michela, Delvecchio, Antonella, Faro, Carmelo Lo, Rosso, Edoardo, Bandyopadhyay, Samik K., Queffurus, Michael, Marin, Jacopo Nicolò, Corvasce, Arianna, Chillarge, Gauri, Mohammed, Mohammed Mustafa, Reid, Rebecca, Gherardi, Dario, Naeem, Awais, Pandanaboyana, Sanjay, Tayeh, Salim, Chevallay, Mickael, Sergeant, Gregory, Cuccomarino, Salvatore, Salimian, Nick, Kapsampelis, Panagiotis, Ferretti, Carlotta, Glasbey, James, Harvitkar, Rafique Umer, Iqbal, Muhammad Rafaih, de Oliveira, Gabriel Paiva, Pérez-Bertólez, Sonia, Bergna, Alessandro, Brisinda, Giuseppe, Rottoli, Matteo, Roscio, Francesco, Pedrazzani, Corrado, Meyer, Jeremy, Marino, Marco V., Brasset, Camille, Daniel, Clerc, Devriendt, Stefanie, Soldini, Gabriele, Pennisi, Damiano, Richards, Chris B., Fiore, Felicia, Bocchino, Antonio, Au, Stephanie, Hernandez-Garcia, Miguel, Frontali, Alice, Grossi, Ugo, Lolis, Evangelos, Miotto, Marco, Di Filippo, Giacomo, Seretis, Charalampos, Barberis, Andrea, De Luca, Raffaele, Levi Sandri, Giovanni Battista, Reitano, Elisa, Mattioli, Marco, Sciaudone, Guido, Fuschillo, Giacomo, Schiltz, Boris, Low, Juin, Bointas, Georgios, Cozza, Valerio, Delaune, Vaihere, Vescio, Francesca, Curcio, Silvia, Sevik, Husnu, Santocchi, Pietro, Stecca, Tommaso, Balaphas, Alexandre, Chessa, Antonella, Leo, Cosimo Alex, di Mola, Fabio F., Tarallo, Mariarita, Martini, Francesco, Lisi, Giorgio, Khan, Mansoor, Nicolazzi, Marco, Pinotti, Enrico, Morini, Andrea, Esposito, Giuseppe, Buonomo, Oreste Claudio, Corallino, Diletta, Demir, Anıl, Roesel, Raffaello, De Lucia, Chiara, Maruccia, Michele, Tekin, Oguzhan, Pavone, Giovanna, Gupta, Ashish, Pradelle, Irene, Chrysikos, Michael, Farrukh, Maira, Baiocchi, Gian Luca, Piras, Carla, Abellán, Antonio Melero, Olivieri, Laura, Materazzo, Marco, Carbone, Ludovico, Dulskas, Audrius, Mulita, Francesk, Corronca, Federico, Cappuccio, Micaela, Smerieri, Elia, Sotiropoulu, Maria, Violante, Tommaso, Moletta, Lucia, Rutegård, Martin, Brillantino, Antonio, Landaluce-Olavarria, Aitor, Ossola, Paolo, Bono, Dario, Rosés, Helena Salvador, Perez-Sanchez, Luis E., Sabbatini, Sonia, Scotti, Mauro Alessandro, Cammarata, Roberto, Ibáñez, Noelia, Marano, Alessandra, Palmisano, Silvia, Cascales-Sanchez, Pedro, Mosca, Vinicio, Ballester, Cristina, Iordache-Petrescu, Madalina Ionela, Pozza, Gioia, Akay, Omer, Bollino, Ruggero, Toti, Johannes M. A., Mascianà, Gianluca, Pach, Radoslaw, Sensi, Bruno, Natalia, Savvala N., Coppola, Alessandro, Altinel, Yuksel, Brucchi, Francesco, Guitart, Marc Pérez, Salido, Andrea Jiménez, Tamini, Nicolò, Garoufalia, Zoe, Mifsut, Patricia, Wilkins, Alex, Navarro-Sánchez, Antonio, Cestaro, Giovanni, Conti, Luigi, Carvas, João M. B., Gazia, Carlo, Alonso, Patricia, Spiezio, Giovanni, Maggi, Giulia, Juloski, Jovan, Braccio, Bartolomeo, Pañella, Clara, Freixa, Celia Caula, Petrakis, Georgios, Folliero, Cristina, De Andrés-Asenjo, Beatriz, Iodice, Alessandra, Jansson, Hannes, González, Tomas Elosua, Ortega, Irene, Castro, Maria J., Fernicola, Agostino, Aparicio, Antonio Carlos Maya, Ortega, Nuria, Chouliaras, Christos, Tura, Marina Vila, Sidiropoulou, Zacharoula, Gonzalez, Ana, Augustin, Goran, Segura-Sampedro, Juan J., Cuk, Vladica, Piccolo, Gaetano, Ingallinella, Sara, Ortenzi, Monica, Uggeri, Fabio, Carrabetta, Salvatore, Tolonen, Matti, Formisano, Giampaolo, Manfredelli, Simone, Perra, Teresa, Esposito, Francesco, Perrone, Gennaro, Zacharis, Georgios, Menéndez, Jaime Iturbe, Bottcher, Sofia Maria Jaume, Ioannidis, Orestis, Borges, Nuno, Sousa, Xavier, Colombari, Renan C., Tellez, Clara, Capolupo, Gabriella Teresa, Giuliani, Giuseppe, Mastella, Federica, González, Lluis García, Merlini, Ilenia, Ghignone, Federico, de Sa, Tiago Correia, Mangana, Orsalia, Rodriguez-Lopez, Mario, Alvarez-Gallego, Mario, Chowdhury, Ashim, Di Lascio, Pierpaolo, Carneros, Virginia Jiménez, Angrisani, Marco, Conte, Luigi E., Montiel, Carmen Galiana, Ascari, Francesca, Dajti, Irida, Lapolla, Pierfrancesco, Sperotto, Beatrice, Mazzarella, Gennaro, Capuano, Marianna, Lopez, Maria Martinez, Ferrario, Luca, Bulte, Joris P., López, María Martínez, Guerci, Claudio, Marra, Angelo Alessandro, Belkacem, Acidi, Pérez, Raquel Escalera, Panyko, Arpád, Dimitrov, Evgeni, Luque, Eduardo J., Manrique, Mario Montes, Paranyak, Mykola, Kaur, Mandeep, Barugola, Giuliano, Farazi-Chongouki, Christos, Estaire-Gómez, Mercedes, del Olmo, Juan Carlos Martín, Nardo, Bruno, Mutlu, Arda Ulaş, Rubio, Ainhoa Valle, Merlini, David A., Marchegiani, Francesco, Cereda, Marco Angelo, Vinci, Danilo, Komaei, Iman, Petrucciani, Niccolo, Seyfried, Steffen, Krsicka, Petr, Medas, Fabio, Lesko, Dusan, Murzi, Valentina, Siragusa, Leandro, Guerrero, María Alejandra, Iranzo, Marina Alarcón, Cestino, Luca, Pasculli, Alessandro, Smerieri, Nazareno, Benzoni, Ilaria, Festa, Federico, Jordão, Daniel Filipe Martins, Licardie, Eugenio, Nicolaescu, Diana C., Balassone, Valerio, La Vaccara, Vincenzo, Romano, Fabrizio, Adamovich, Dmitry Mikhailovich, Papatheodorou, Panayiotis, Maroni, Norvana, Colás-Ruiz, Enrique, Melberga, Liene, Chimenti, Federica, Ferrari, Davide, Arcudi, Claudio, Police, Andrea, De Simone, Belinda, Sánchez-Guillén, Luis, Parreño-Manchado, Felipe Carlos, Rachadell, Juan José, Coletta, Diego, Saroglu, Azize, Pattacini, Gianmaria Casoni, Antonelli, Amedeo, Anania, Marco, Litta, Francesco, Lafranceschina, Stefano, Bottari, Andrea, Pavlovic, Mladen, Rojas-Bonet, Noel, Tampaki, Ekaterini Christina, Kosir, Jurij A., Anelli, Ferdinando M., de las Casas, Sara Gortázar, Kucukarslan, Rabia, Pierobon, Elisa Sefora, Milanesi, Maria, Drogouti, Maria, Sotiropoulou, Maria, Di Marco, Federica, Bannone, Elisa, Sliwinski, Svenja Christin, Yildiz, Ishak, Pellicciaro, Marco, Celotti, Andrea, Malerba, Michele, Marino, Fabio, Bourmpouteli, Eirini, Bianco, Giuseppe, Charitaki, Evgenia, Pascale, Marco Maria, Ioannidis, Argyrios, Maraska, Fatlum, Petagna, Lorenzo, Turri, Giulia, Vailas, Michail, Romanzi, Andrea, Pouwels, Sjaak, Rosa, Fausto, Clocchiatti, Lucrezia, Andreuccetti, Jacopo, Machairas, Nikolaos, Frountzas, Maximos, Lasithiotakis, Konstantinos, Barone, Mirko, Christodoulou, Prokopis, Potkonjak, Dario, Aiolfi, Alberto, de Vries, Hilbert S., Napetti, Sara, Castaldi, Antonio, Botelho, Pedro, Marziali, Irene, Uccelli, Matteo, Pisano, Michele, Veroux, Massimiliano, Locci, Eleonora, Romano, Angela, Cero, Mariagiulia Dal, Cicerchia, Pierfranco Maria, Baldi, Caterina, Russo, Iris Shari, Tenconi, Silvia Maria, Saliu, Fatmir, Bondurri, Andrea, Cardinali, Luca, Laracca, Giovanni Guglielmo, Martín-Pérez, Beatriz, Felsenreich, Daniel M., Cunha, Miguel, Zerbo, Domenico, Clementi, Marco, Delogu, Daniele, Iossa, Angelo, Bavikatte, Akshay Prasannakumar, Saracoglu, Can, Pecorelli, Nicolò, Tufo, Andrea, Biloslavo, Alan, Lianos, Georgios D., Carannante, Filippo, Costanzo, Antonio, Montuori, Mauro, Cigognini, Maria, Silvestro, Roberto, Atici, Semra Demirli, Milito, Pamela, Ferronetti, Antonio, Güngör, Mert, Di Venere, Beatrice, Puccioni, Caterina, De Nobili, Giovanni, Selvaggi, Lucio, Farolfi, Tommaso, Aeschbacher, Pauline, Olivier, James B., Frazzetta, Giuseppe, Andriola, Valeria, Giordano, Alessio, De Luca, Alessandro, Ferrara, Francesco, Casagranda, Biagio, Sammartano, Fabrizio, Russo, Alfio Alessandro, Rossi, Stefano, Pacilli, Mario, Synekidou, Eirini, Tutino, Roberta, Ceresoli, Marco, De Rosa, Michele, Di Santo Albini, Andrea G., Vincenzi, Paolo, Vellei, Samantha, Benzoni, Enrico, Murillo, Gabriela Aracelly Arroyo, Izzo, Giuliano, Scotto, Bruno, Caruso, Riccardo, Colombo, Francesco, D'Acapito, Fabrizio, Lostoridis, Eftychios, Saladino, Edoardo, Poillucci, Gaetano, Moeckli, Beat, Manto, Ottavia, Kara, Yasin, Tatar, Cihad, Cioffi, Stefano Piero Bernardo, Mambrilla, Sara, Bianchi, Valentina, Scopelliti, Michele, Agresta, Ferdinando, Nava, Andrea Kazemi, Franchi, Eloisa, Fransvea, Pietro, Prieto, Mikel, Picardi, Biagio, Rizzuto, Antonia, Panaccio, Paolo, Gussago, Stefano, Marra, Ester, Addeo, Pietro, Fernández Fernández, June, Gulmez, Mehmet, Pisaniello, Donatella, Cannavo, Maurizio, López-López, Victor, Avella, Pasquale, Peloso, Andrea, Bellanova, Giovanni, Candilio, Giuseppe, Perotti, Bruno, Granata, Roberta, Florio, Gaetano, Ioia, Giovanna, Iannone, Immacolata, Ammerata, Giorgio, Zambon, Martina, Romano, Francesco Maria, Del Monte, Simone Rossi, Sasia, Diego, Fortuna, Laura, Giuffrida, Mario, Litvin, Andrey, Cannistra, Marco, De Padua, Cristina, Sánchez, Tatiana Gómez, Paniagua-Garcia-Señorans, Marta, Guevara, Jenny, Perfecto, Arkaitz, Alconchel, Felipe, Campanelli, Michela, Keci, Laura, Cricrì, Michele, Kampouroglou, Georgios, Bagaglini, Giulia, Farrarons, Sara Sentí, Greco, Antonio, Walędziak, Maciej, Carvas, João M., Serrano-Navidad, Monica, Van Doorn, Berend, Schiavo, Ciro, Fabbri, Nicolò, Wani, Ishfaq Ahmad, Mondi, Isabella, Anestiadou, Elissavet, Mendes, Beatriz ISilva, Verdi, Daunia, Dorovinis, Panagiotis, Cacciaguerra, Andrea Benedetti, Caldeira, Beatriz, Canonico, Giuseppe, Dardanov, Dragomir, D'Ugo, Stefano, Francis, Fayez Maged, Meneghini, Simona, Pesce, Antonio, Puglisi, Silvana Bernadetta, Bellini, Maria Irene, Pisano, Marcello, Giordano, Marco, Fleres, Francesco, Campus, Federica, Cillara, Nicola, Moggia, Elisabetta, Ciarleglio, Francesco A., Calini, Giacomo, Gravante, Gianpiero, De Carlis, Riccardo, Altomare, Michele, Martines, Gennaro, Miggino, Marco, Marano, Luigi, Stocco, Alberto, Porcu, Alberto, Pham, Thuy Vy, Gervasi, Maria Clelia, Pilia, Tiziana, Palomba, Giuseppe, Picchetto, Andrea, Spampinato, Marcello Giuseppe, Tandoi, Francesco, Piccoli, Micaela, Gall, Malina ECaraiman, Santos, Bárbara Ribeiro, Agastra, Ervis, Koëter, Tijmen, Samadov, Elgun, Marsanic, Patrizia, Serena, De Fatico Gilda, Uzunoglu, Mustafa Yener, Zanus, Giacomo, Braholli, Eriol, Giovine, Gennaro, Galiffa, Giampaolo, Lauricella, Sara, Lukmonov, Saidrakhim, Leventoglu, Sezai, Chooklin, Serge, Dudi-Venkata, Nagendra N., Gauci, Chahaya M., Podda, M, Di Martino, M, Pata, F, Nigri, G, Pisanu, A, Di Saverio, S, Pellino, G, Ielpo, B, Null, N, Tolla, A, Abdelkhalek, M, Emile, S, Dinagde, T, Bouzid, C, Mansour, A, Garzali, I, Aregawi, A, Zaghloul, T, Kchaou, A, Awad, S, Souadka, A, Ted, T, Saumtally, M, Ahmed, B, Bayileyegn, N, Nunziante, M, Shalaby, M, Debena, D, Zena, A, Adewunmi, O, Negasa, T, Bourguiba, M, Feituri, N, Kebede, K, Elfeki, H, Anas, A, Awad, A, Ermias, N, Hailemariam, D, Bejiga, G, Imana, R, Taffese, A, Feleke, T, Elghadban, H, Debela, B, Shiferaw, D, Tadesse, R, Chukwu, I, Mohammed, A, Hassen, K, Obiagwu, N, Tense, T, Taeme, M, Biniam, E, Tesfay, G, Tegegn, A, Teddy, T, Bekana, B, Nidaw, M, Ali, M, Gonfa, K, Kiros, S, Belay, T, Yallew, G, Wassie, C, 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Giovine, G, Galiffa, G, Lauricella, S, Lukmonov, S, Leventoglu, S, Chooklin, S, Dudi-Venkata, N, Gauci, C, Podda, Mauro, Di Martino, Marcello, Pata, Francesco, Nigri, Giuseppe, Pisanu, Adolfo, Di Saverio, Salomone, Pellino, Gianluca, Ielpo, Benedetto, null, null, Tolla, Ashenafi Negash, Abdelkhalek, Mohamed, Emile, Sameh, Dinagde, Tesfaye Aga, Bouzid, Chafik, Mansour, Ahmed Mohammed Farid Mahmoud, Garzali, Ibrahim Umar, Aregawi, Alazar Berhe, Zaghloul, Tarek M., Kchaou, Ali, Awad, Selmy S., Souadka, Amine, Ted, Tedla Gebretsadik, Saumtally, Mohammad Saad, Ahmed, Bensaad, Bayileyegn, Nebiyou Simegnew, Nunziante, Marco, Shalaby, Mostafa, Debena, Dawit Gebregiorgis, Zena, Alemayehu Shanko, Adewunmi, Olayinka Lukman, Negasa, Tolera A., Bourguiba, Mohamed Aboulkacem, Feituri, Nura, Kebede, Kirubel Abebe, Elfeki, Hossam, Anas, Abdelhmed, Awad, Ahmed K., Ermias, Nebiyou, Hailemariam, Dagnachew H., Bejiga, Gosa Hundie, Imana, Ruhama Yoseph, Taffese, Abebe, Feleke, Tsega Terefe, Elghadban, Hosam Mohamed, Debela, Bizuneh Sime, Shiferaw, Desta, Tadesse, Robel, Chukwu, Isaac Sunday, Mohammed, Abdullahi Ibrahim, Hassen, Khalid Arebo, Obiagwu, Ndubuisi K., Tense, Tadesse H., Taeme, Mulugeta, Biniam, Ewnte, Tesfay, Goytom Knfe, Tegegn, Ayenachew Getachew, Teddy, Tewodros Abule Bilata, Bekana, Bekana L., Nidaw, Melkamu Kibret, Ali, Mahmoud Ibrahim, Gonfa, Kebebe Bekele, Kiros, Samuel, Belay, Tatek, Yallew, Gebeyaw Mengist, Wassie, Chekol, Ayalew, Alem Mekete, Asfaw, Fitsum Terefe, Aimal, Aimal Khan, Casas, Maria Agustina, Madrid, Fausto A., Diaz-Elizondo, Jose Antonio, Merlo, Ignacio Guillermo, De Campos, Tercio, Schlottmann, Francisco, Gomes, Carlos Augusto, Hernández, Edgard Efrén Lozada, Moncada-Ortega, Augusto, Ramos-De la Medina, Antonio, Vanerio, Patricio, Morales, Emilio J., Stringfield, Sarah Beth, Gallardo, Cristian, Fonseca, Vinicius Cordeiro, Muriel, Maria Emilia, Cantarino, Frederico, Fichera, Alessandro, Rodriguez, Agustin E., Salinas, Roberto Paúl Andrade, Crosbie, Gonzalo Gabriel, Menegozzo, Carlos Augusto Metidieri, Avellaneda, Nicolas, Briones, Cristhian Gonzalo Aspiazu, Varela, Cristopher, Lichliter, Warren E., Varela, Cristopher L., Koppel, Darren, Lenz, Jorge Godoy, Pascual, Franco, Sibaja-Matamoros, Dauber A., Johnson, Benjamin E., Mercado, Octavio Avila, Tita, Agustín, Mukherjee, Indraneil, Lorenzo, Irving, Rueda, Erick, Rico, Douglas, Terwes, Natasha Loria, Visag-Castillo, Victor, Escalante, Karol S., Salvador, Alan Francisco Alfaro, Pio, Luca, Rodas, Edgar B., Aguilar, Juan Carlos Cardozo, Neri, Ignacio, Barzola, Ernesto J., Barba, Leonardo A., Zuchini, Andrés Mendoza, Acevedo, Ana Karen Radilla, Gachabayov, Mahir, Gonsaga, Ricardo Alessandro Teixeira, Bonilla, Fernando, Knickerbocker, Chase Barrett, Tsouknidas, Ioannis, Salamea, Juan C., Travers, Lawrence Albert Salter, Nari, Gustavo Adrian, Pachajoa, Diana Alejandra Pantoja, Valadez, Michel Hernandez, Hale, Lyman Lansing, Perez, Guillermo, Choudhry, Asad, Foreman, Michaael L., Brito, Ismael, Ciro, Mauricio Pedraza, Newton, Carla Joyce, Souza, Hamilton Petry, Davis, Daniel G., Ferreira, Rodrigo Vaz, Keller, Deborah S., Miguel, Gustavo Machain, Singh-Ranger, Gurpreet, Linares, Neiling Massiel Oviedo, Singares, Eduardo Smith, Valdivieso, Xavier HGarcía, Teran, Alfonso Ivan Sanchez, Vargas, Luis Felipe Cabrera, Valinoti, Agustín, Milne, David M., Fleming, Andrew Martin, Quiroga-Garza, Alejandro, Espino, Eduardo Morales, Bedros, Nicole Mary, Funk, Geoffrey A., Neves, Fernanda V. S., Supit, Tommy, Baba, Arshad Ahmed, Chalkoo, Mushtaq A., Kucuk, Gultekin Ozan, Sarmiento, Ray Inocencio, Galeev, Shamil I., Korkoman, Mohammed J., Yang, Wah, Medappil, Noushif, Athar, Rahmatullah, Subramaniam, Ravichandran, Chia, Chi Fung, Alhazmi, Ahmad, Halder, Subhadip, Rusli, Siti Mayuha, Rashid, Arshad, Gülcü, Barış, Nagarajan, Prasanth, Rida, Khaled, Jamiri, Al-Radjid, Batıkan, Oğuzkağan, Khan, Huma Ahmed, Mitul, Ashrarur Rahman, Efetov, Sergey, Junior, Marcelo A. F. Ribeiro, Gulcu, Baris, Farooqui, Marryam Riaz, Mulpuri, Venu Bhargava, Bagaria, Dinesh, Yusoff, Ahmad Ramzi, Wani, Rauf, Younis, Muhammad Umar, Khobragade, Krunal H., Marwat, Muhammad Ibrahim, Bains, Lovenish, Kobe, Yoshiro, Koh, Peng Soon, Tantravahi, Umasankar, Mohamad Mohamad, Ikhwan Sani, Abu-Arish, Hamdoon, Yildirim, Ali Cihat, Ibrahim, Aini Fahriza, Tan, Jih Huei, Siagian, Dumaria Ketty, Bhattacharya, Neela, Chiu, Jennifer H. F., Paramasvaran, Ganendra, Voon, Kelvin, Göktepe, Berk, Lee, Lee Yeong Sing, Gupta, Amit, Rasheed, Faaiz, Al-Shehari, Mohammed, Syed, Syed Muhammad Ali, Bhat, Pawan Singh, Erdoğan, Emre, Roat, Rajesh, Nacion, Aeris Jane D., Saraiya, Swapnil Mukesh, Afolabi, Akinwale Ibrahim, Chai, Feng Yih, Ghannam, Wagih, Bhattacharya, Kaushik, NL, Harish, Aloun, Ali, Bhatti, Hamza Waqar, Koneti, Akshadhar J., Klib, Mohamad, Qureshi, Ahmad Uzair, Syn, Nicholas L., Wani, Ajaz, Saeidi, Sara, Zeb, Muhammad, Bandaru, Kalyan Vijay Kumar, Menna, Maria Paola, Morales-Conde, Salvador, Gessa, Emanuela, Sánchez-Cabús, Santiago, Spartalis, Eleftherios, Antropoli, Carmine, Manigrasso, Michele, Sica, Giuseppe S., Ercolani, Giorgio, Chitul, Andrei, Bacchiocchi, Giulia, Azevedo, José, Karamarkovic, Aleksandar, Bonavina, Luigi, Piozzi, Guglielmo N., Migueláñez, Isabel Pascual, Merlini, David, Major, Piotr, Grimaldi, Luciano, Calu, Valentin, Curro, Giuseppe, Cotsoglou, Christian, Baldini, Edoardo, Delis, Spiros, Kovacevic, Bojan, Masetti, Michele, Selvaggi, Francesco, Scabini, Stefano, Reiti, Andrian, Zullo, Alessia, Giuliani, Antonio, Alesina, Pier Francesco, Massey, Lisa H., Slesser, Alistair A. P., Neary, Peter M., Sahnan, Kapil, Tan, Jessica J., Colucci, Gianluca, Brady, Richard R. W., Mihailescu, Andrei, Adamina, Michel, Gerogiannis, Ioannis, van Ramshorst, Gabrielle, Paradiso, Giulia, Poto, Gianmario Edoardo, Massaro, Daniele, Nazir, Fozia, Stubbs, Benjamin M., Tasselli, Francesco Menegon, Muñoz-Cruzado, Virginia Durán, Sabia, Domenico, Vannelli, Alberto, Marsella, Valentina Enrica, Tomada, Elisa Paoluzzi, Giambusso, Mauro, Davies, Justin, Uzzau, Alessandro, Balla, Andrea, Scaringi, Stefano, Lancellotti, Francesco, Douka, Eleftheria, Argenio, Giulio, Cassese, Gianluca, Ammendola, Michele, Morelli, Luca, Francone, Elisa, Bala, Miklosh, Thambi, Prem, Iacobone, Maurizio, Campisi, Andrea, Tejedor, Patricia, Spoletini, Gabriele, Mascherini, Matteo, Belia, Francesco, Idiz, Ufuk Oguz, Colak, Elif, Peters, Paul Adewunmi, Ros, Emilio Peña, Aytac, Erman, Vilallonga, Ramon, Serrablo, Alejandro, Muttillo, Edoardo Maria, Di Franco, Gregorio, Vanni, Gianluca, Isik, Arda, Sbacco, Valentina, Tropeano, Francesca Paola, Porcellini, Iride, Butler, Rebecca Jayne, Fernandez, Carmen Cagigas, Papadopoulos, Aristeidis, Salvans, Silvia, Khan, Jan Sher, Bellver, Pedro Palazón, Mc Farlane, Sebastian Jeri, Apostolou, Konstantinos, Tur-Martinez, Jaume, Castellano, Javier Rivera, Santoliquido, Matteo, Tallon-Aguilar, Luis, Celentano, Valerio, Aliyev, Vusal, al-Najami, Issam, Grama, Florin A., Masior, Łukasz, Ciesielski, Wojciech J., Luberto, Antonio, Sparavigna, Marco, Klimczak, Tomasz Jerzy, Negoi, Ionut, Serradilla-Martín, Mario, Marinis, Athanasios, Cammarat, Roberto, Bellido-luque, Juan, Manzo, Carlo Alberto, Milana, Flavio, Luglio, Gaetano, Zarnescu, Narcis Octavian, Martínez, Isidro, Olmi, Stefano, Costea, Radu V., Cerdán-Santacruz, Carlos, Gica, Nicolae, Rompianesi, Gianluca, Gallo, Gaetano, Ridolfi, Cristina, Sahid, Saidah, CC, Tommaso, López-Soler, Guillermo, Díaz, Carlos JGómez, Mccawley, Niamh, Luzzi, Andrea Pierre, Abelló, David, Bonito, Alba Correa, Ntomi, Vasileia, Gourgiotis, Stavros, Pazos, Natalia Suárez, Toscano, Marta Jiménez, Zafra, David Ambrona, Beisani, Marc, Oliva, Alba, Guler, Mert, Gómez, Marta Jiménez, Oddis, Lidia, Montcusí, Blanca, Delgado, Ander Timoteo, Lasarte, Mateusz PJęckowski Aingeru Sarriuga, Antonacci, Nicola, Sartori, Alberto, Taylor, John Vincent, de Santos Iglesias, Francisco Juan, Mastronardi, Manuela, Gunay, Emre, Yiu, Andrew, Cano-Valderrama, Oscar, Costantini, Giulia, Digne-Malcolm, Holly Jane, Petropoulou, Thalia, Horesh, Nir, Kelly, Michael E., Ahmed, Nauman, Wyroslak-Najs, Justyna, Naik, Prashant, Vigorita, Vincenzo, Michael, Michael, Castro, Ernest, Paspala, Anna, D'Ambrosio, Marco, Pangeni, Anang, Dziakova, Jana, Terés, Lara Blanco, Lorente-Poch, Leyre, Di Carlo, Isidoro, Spartalis, Michael, Moro-Valdezate, David, Davey, Matthew G., Turrado-Rodriguez, Victor, Tryliskyy, Yegor, Calussi, Marco, Farré, Silvia Pérez, Labat, Miriam Cazador, Marafante, Chiara, Takkenberg, Marijn, Brookes, Charlotte Elisabeth, Soares, Antonio S., Gialamas, Eleftherios, Caputo, Damiano, Corrons, Laia Codina, Capitano, Sante, Charalabopoulos, Alexandros, Don, Cristine Brooke Pathirannehalage, Marrano, Enrico, Giuffrida, Maria Carmela, Tomasicchio, Giovanni, Bellato, Vittoria, Stijns, Jasper, Creavin, Ben, Schizas, Dimitrios, Blanco-Antona, Francisco, Kykalos, Stylianos, Tartaglia, Nicola, Pelegrina, Amalia, Barranquero, Alberto G., Schena, Carlo Alberto, Cremona, Simone, Baili, Efstratia, Cianci, Pasquale, Di Bella, Annamaria, Forcignanò, Edoardo, Fabbrizio, Tiziana, Salvetti, Francesco, Inama, Marco, Campagnaro, Tommaso, Deerenberg, Eva B., Reccia, Isabella, Rocca, Aldo, Fazio, Federico, Tampakis, Athanasios, Tepelenis, Kostas, Di Meo, Giovanna, Konstantoudakis, Georgios, Manatakis, Dimitrios K., Mineccia, Michela, Delvecchio, Antonella, Faro, Carmelo Lo, Rosso, Edoardo, Bandyopadhyay, Samik K., Queffurus, Michael, Marin, Jacopo Nicolò, Corvasce, Arianna, Chillarge, Gauri, Mohammed, Mohammed Mustafa, Reid, Rebecca, Gherardi, Dario, Naeem, Awais, Pandanaboyana, Sanjay, Tayeh, Salim, Chevallay, Mickael, Sergeant, Gregory, Cuccomarino, Salvatore, Salimian, Nick, Kapsampelis, Panagiotis, Ferretti, Carlotta, Glasbey, James, Harvitkar, Rafique Umer, Iqbal, Muhammad Rafaih, de Oliveira, Gabriel Paiva, Pérez-Bertólez, Sonia, Bergna, Alessandro, Brisinda, Giuseppe, Rottoli, Matteo, Roscio, Francesco, Pedrazzani, Corrado, Meyer, Jeremy, Marino, Marco V., Brasset, Camille, Daniel, Clerc, Devriendt, Stefanie, Soldini, Gabriele, Pennisi, Damiano, Richards, Chris B., Fiore, Felicia, Bocchino, Antonio, Au, Stephanie, Hernandez-Garcia, Miguel, Frontali, Alice, Grossi, Ugo, Lolis, Evangelos, Miotto, Marco, Di Filippo, Giacomo, Seretis, Charalampos, Barberis, Andrea, De Luca, Raffaele, Levi Sandri, Giovanni Battista, Reitano, Elisa, Mattioli, Marco, Sciaudone, Guido, Fuschillo, Giacomo, Schiltz, Boris, Low, Juin, Bointas, Georgios, Cozza, Valerio, Delaune, Vaihere, Vescio, Francesca, Curcio, Silvia, Sevik, Husnu, Santocchi, Pietro, Stecca, Tommaso, Balaphas, Alexandre, Chessa, Antonella, Leo, Cosimo Alex, di Mola, Fabio F., Tarallo, Mariarita, Martini, Francesco, Lisi, Giorgio, Khan, Mansoor, Nicolazzi, Marco, Pinotti, Enrico, Morini, Andrea, Esposito, Giuseppe, Buonomo, Oreste Claudio, Corallino, Diletta, Demir, Anıl, Roesel, Raffaello, De Lucia, Chiara, Maruccia, Michele, Tekin, Oguzhan, Pavone, Giovanna, Gupta, Ashish, Pradelle, Irene, Chrysikos, Michael, Farrukh, Maira, Baiocchi, Gian Luca, Piras, Carla, Abellán, Antonio Melero, Olivieri, Laura, Materazzo, Marco, Carbone, Ludovico, Dulskas, Audrius, Mulita, Francesk, Corronca, Federico, Cappuccio, Micaela, Smerieri, Elia, Sotiropoulu, Maria, Violante, Tommaso, Moletta, Lucia, Rutegård, Martin, Brillantino, Antonio, Landaluce-Olavarria, Aitor, Ossola, Paolo, Bono, Dario, Rosés, Helena Salvador, Perez-Sanchez, Luis E., Sabbatini, Sonia, Scotti, Mauro Alessandro, Cammarata, Roberto, Ibáñez, Noelia, Marano, Alessandra, Palmisano, Silvia, Cascales-Sanchez, Pedro, Mosca, Vinicio, Ballester, Cristina, Iordache-Petrescu, Madalina Ionela, Pozza, Gioia, Akay, Omer, Bollino, Ruggero, Toti, Johannes M. A., Mascianà, Gianluca, Pach, Radoslaw, Sensi, Bruno, Natalia, Savvala N., Coppola, Alessandro, Altinel, Yuksel, Brucchi, Francesco, Guitart, Marc Pérez, Salido, Andrea Jiménez, Tamini, Nicolò, Garoufalia, Zoe, Mifsut, Patricia, Wilkins, Alex, Navarro-Sánchez, Antonio, Cestaro, Giovanni, Conti, Luigi, Carvas, João M. B., Gazia, Carlo, Alonso, Patricia, Spiezio, Giovanni, Maggi, Giulia, Juloski, Jovan, Braccio, Bartolomeo, Pañella, Clara, Freixa, Celia Caula, Petrakis, Georgios, Folliero, Cristina, De Andrés-Asenjo, Beatriz, Iodice, Alessandra, Jansson, Hannes, González, Tomas Elosua, Ortega, Irene, Castro, Maria J., Fernicola, Agostino, Aparicio, Antonio Carlos Maya, Ortega, Nuria, Chouliaras, Christos, Tura, Marina Vila, Sidiropoulou, Zacharoula, Gonzalez, Ana, Augustin, Goran, Segura-Sampedro, Juan J., Cuk, Vladica, Piccolo, Gaetano, Ingallinella, Sara, Ortenzi, Monica, Uggeri, Fabio, Carrabetta, Salvatore, Tolonen, Matti, Formisano, Giampaolo, Manfredelli, Simone, Perra, Teresa, Esposito, Francesco, Perrone, Gennaro, Zacharis, Georgios, Menéndez, Jaime Iturbe, Bottcher, Sofia Maria Jaume, Ioannidis, Orestis, Borges, Nuno, Sousa, Xavier, Colombari, Renan C., Tellez, Clara, Capolupo, Gabriella Teresa, Giuliani, Giuseppe, Mastella, Federica, González, Lluis García, Merlini, Ilenia, Ghignone, Federico, de Sa, Tiago Correia, Mangana, Orsalia, Rodriguez-Lopez, Mario, Alvarez-Gallego, Mario, Chowdhury, Ashim, Di Lascio, Pierpaolo, Carneros, Virginia Jiménez, Angrisani, Marco, Conte, Luigi E., Montiel, Carmen Galiana, Ascari, Francesca, Dajti, Irida, Lapolla, Pierfrancesco, Sperotto, Beatrice, Mazzarella, Gennaro, Capuano, Marianna, Lopez, Maria Martinez, Ferrario, Luca, Bulte, Joris P., López, María Martínez, Guerci, Claudio, Marra, Angelo Alessandro, Belkacem, Acidi, Pérez, Raquel Escalera, Panyko, Arpád, Dimitrov, Evgeni, Luque, Eduardo J., Manrique, Mario Montes, Paranyak, Mykola, Kaur, Mandeep, Barugola, Giuliano, Farazi-Chongouki, Christos, Estaire-Gómez, Mercedes, del Olmo, Juan Carlos Martín, Nardo, Bruno, Mutlu, Arda Ulaş, Rubio, Ainhoa Valle, Merlini, David A., Marchegiani, Francesco, Cereda, Marco Angelo, Vinci, Danilo, Komaei, Iman, Petrucciani, Niccolo, Seyfried, Steffen, Krsicka, Petr, Medas, Fabio, Lesko, Dusan, Murzi, Valentina, Siragusa, Leandro, Guerrero, María Alejandra, Iranzo, Marina Alarcón, Cestino, Luca, Pasculli, Alessandro, Smerieri, Nazareno, Benzoni, Ilaria, Festa, Federico, Jordão, Daniel Filipe Martins, Licardie, Eugenio, Nicolaescu, Diana C., Balassone, Valerio, La Vaccara, Vincenzo, Romano, Fabrizio, Adamovich, Dmitry Mikhailovich, Papatheodorou, Panayiotis, Maroni, Norvana, Colás-Ruiz, Enrique, Melberga, Liene, Chimenti, Federica, Ferrari, Davide, Arcudi, Claudio, Police, Andrea, De Simone, Belinda, Sánchez-Guillén, Luis, Parreño-Manchado, Felipe Carlos, Rachadell, Juan José, Coletta, Diego, Saroglu, Azize, Pattacini, Gianmaria Casoni, Antonelli, Amedeo, Anania, Marco, Litta, Francesco, Lafranceschina, Stefano, Bottari, Andrea, Pavlovic, Mladen, Rojas-Bonet, Noel, Tampaki, Ekaterini Christina, Kosir, Jurij A., Anelli, Ferdinando M., de las Casas, Sara Gortázar, Kucukarslan, Rabia, Pierobon, Elisa Sefora, Milanesi, Maria, Drogouti, Maria, Sotiropoulou, Maria, Di Marco, Federica, Bannone, Elisa, Sliwinski, Svenja Christin, Yildiz, Ishak, Pellicciaro, Marco, Celotti, Andrea, Malerba, Michele, Marino, Fabio, Bourmpouteli, Eirini, Bianco, Giuseppe, Charitaki, Evgenia, Pascale, Marco Maria, Ioannidis, Argyrios, Maraska, Fatlum, Petagna, Lorenzo, Turri, Giulia, Vailas, Michail, Romanzi, Andrea, Pouwels, Sjaak, Rosa, Fausto, Clocchiatti, Lucrezia, Andreuccetti, Jacopo, Machairas, Nikolaos, Frountzas, Maximos, Lasithiotakis, Konstantinos, Barone, Mirko, Christodoulou, Prokopis, Potkonjak, Dario, Aiolfi, Alberto, de Vries, Hilbert S., Napetti, Sara, Castaldi, Antonio, Botelho, Pedro, Marziali, Irene, Uccelli, Matteo, Pisano, Michele, Veroux, Massimiliano, Locci, Eleonora, Romano, Angela, Cero, Mariagiulia Dal, Cicerchia, Pierfranco Maria, Baldi, Caterina, Russo, Iris Shari, Tenconi, Silvia Maria, Saliu, Fatmir, Bondurri, Andrea, Cardinali, Luca, Laracca, Giovanni Guglielmo, Martín-Pérez, Beatriz, Felsenreich, Daniel M., Cunha, Miguel, Zerbo, Domenico, Clementi, Marco, Delogu, Daniele, Iossa, Angelo, Bavikatte, Akshay Prasannakumar, Saracoglu, Can, Pecorelli, Nicolò, Tufo, Andrea, Biloslavo, Alan, Lianos, Georgios D., Carannante, Filippo, Costanzo, Antonio, Montuori, Mauro, Cigognini, Maria, Silvestro, Roberto, Atici, Semra Demirli, Milito, Pamela, Ferronetti, Antonio, Güngör, Mert, Di Venere, Beatrice, Puccioni, Caterina, De Nobili, Giovanni, Selvaggi, Lucio, Farolfi, Tommaso, Aeschbacher, Pauline, Olivier, James B., Frazzetta, Giuseppe, Andriola, Valeria, Giordano, Alessio, De Luca, Alessandro, Ferrara, Francesco, Casagranda, Biagio, Sammartano, Fabrizio, Russo, Alfio Alessandro, Rossi, Stefano, Pacilli, Mario, Synekidou, Eirini, Tutino, Roberta, Ceresoli, Marco, De Rosa, Michele, Di Santo Albini, Andrea G., Vincenzi, Paolo, Vellei, Samantha, Benzoni, Enrico, Murillo, Gabriela Aracelly Arroyo, Izzo, Giuliano, Scotto, Bruno, Caruso, Riccardo, Colombo, Francesco, D'Acapito, Fabrizio, Lostoridis, Eftychios, Saladino, Edoardo, Poillucci, Gaetano, Moeckli, Beat, Manto, Ottavia, Kara, Yasin, Tatar, Cihad, Cioffi, Stefano Piero Bernardo, Mambrilla, Sara, Bianchi, Valentina, Scopelliti, Michele, Agresta, Ferdinando, Nava, Andrea Kazemi, Franchi, Eloisa, Fransvea, Pietro, Prieto, Mikel, Picardi, Biagio, Rizzuto, Antonia, Panaccio, Paolo, Gussago, Stefano, Marra, Ester, Addeo, Pietro, Fernández Fernández, June, Gulmez, Mehmet, Pisaniello, Donatella, Cannavo, Maurizio, López-López, Victor, Avella, Pasquale, Peloso, Andrea, Bellanova, Giovanni, Candilio, Giuseppe, Perotti, Bruno, Granata, Roberta, Florio, Gaetano, Ioia, Giovanna, Iannone, Immacolata, Ammerata, Giorgio, Zambon, Martina, Romano, Francesco Maria, Del Monte, Simone Rossi, Sasia, Diego, Fortuna, Laura, Giuffrida, Mario, Litvin, Andrey, Cannistra, Marco, De Padua, Cristina, Sánchez, Tatiana Gómez, Paniagua-Garcia-Señorans, Marta, Guevara, Jenny, Perfecto, Arkaitz, Alconchel, Felipe, Campanelli, Michela, Keci, Laura, Cricrì, Michele, Kampouroglou, Georgios, Bagaglini, Giulia, Farrarons, Sara Sentí, Greco, Antonio, Walędziak, Maciej, Carvas, João M., Serrano-Navidad, Monica, Van Doorn, Berend, Schiavo, Ciro, Fabbri, Nicolò, Wani, Ishfaq Ahmad, Mondi, Isabella, Anestiadou, Elissavet, Mendes, Beatriz ISilva, Verdi, Daunia, Dorovinis, Panagiotis, Cacciaguerra, Andrea Benedetti, Caldeira, Beatriz, Canonico, Giuseppe, Dardanov, Dragomir, D'Ugo, Stefano, Francis, Fayez Maged, Meneghini, Simona, Pesce, Antonio, Puglisi, Silvana Bernadetta, Bellini, Maria Irene, Pisano, Marcello, Giordano, Marco, Fleres, Francesco, Campus, Federica, Cillara, Nicola, Moggia, Elisabetta, Ciarleglio, Francesco A., Calini, Giacomo, Gravante, Gianpiero, De Carlis, Riccardo, Altomare, Michele, Martines, Gennaro, Miggino, Marco, Marano, Luigi, Stocco, Alberto, Porcu, Alberto, Pham, Thuy Vy, Gervasi, Maria Clelia, Pilia, Tiziana, Palomba, Giuseppe, Picchetto, Andrea, Spampinato, Marcello Giuseppe, Tandoi, Francesco, Piccoli, Micaela, Gall, Malina ECaraiman, Santos, Bárbara Ribeiro, Agastra, Ervis, Koëter, Tijmen, Samadov, Elgun, Marsanic, Patrizia, Serena, De Fatico Gilda, Uzunoglu, Mustafa Yener, Zanus, Giacomo, Braholli, Eriol, Giovine, Gennaro, Galiffa, Giampaolo, Lauricella, Sara, Lukmonov, Saidrakhim, Leventoglu, Sezai, Chooklin, Serge, Dudi-Venkata, Nagendra N., and Gauci, Chahaya M.
- Abstract
The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS (R) v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 +/- 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 +/- 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 +/- 4.9 and 7.8 +/- 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 +/- 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI.
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- 2024
11. Predicting the future of our oceans : Evaluating genomic forecasting approaches in marine species
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Layton, K. K. S., Brieuc, M. S. O., Castilho, R., Diaz-Arce, N., Estévez-Barcia, D., Fonseca, V. G., Fuentes-Pardo, Angela P., Jeffery, N. W., Jiménez-Mena, B., Junge, C., Kaufmann, J., Leinonen, T., Maes, S. M., Mcginnity, P., Reed, T. E., Reisser, C. M. O., Silva, G., Vasemägi, A., Bradbury, I. R., Layton, K. K. S., Brieuc, M. S. O., Castilho, R., Diaz-Arce, N., Estévez-Barcia, D., Fonseca, V. G., Fuentes-Pardo, Angela P., Jeffery, N. W., Jiménez-Mena, B., Junge, C., Kaufmann, J., Leinonen, T., Maes, S. M., Mcginnity, P., Reed, T. E., Reisser, C. M. O., Silva, G., Vasemägi, A., and Bradbury, I. R.
- Abstract
Climate change is restructuring biodiversity on multiple scales and there is a pressing need to understand the downstream ecological and genomic consequences of this change. Recent advancements in the field of eco-evolutionary genomics have sought to include evolutionary processes in forecasting species' responses to climate change (e.g., genomic offset), but to date, much of this work has focused on terrestrial species. Coastal and offshore species, and the fisheries they support, may be even more vulnerable to climate change than their terrestrial counterparts, warranting a critical appraisal of these approaches in marine systems. First, we synthesize knowledge about the genomic basis of adaptation in marine species, and then we discuss the few examples where genomic forecasting has been applied in marine systems. Next, we identify the key challenges in validating genomic offset estimates in marine species, and we advocate for the inclusion of historical sampling data and hindcasting in the validation phase. Lastly, we describe a workflow to guide marine managers in incorporating these predictions into the decision-making process. Predicting climate change impacts is of central importance in marine ecosystems that provide a major source of nutrition to global communities and this work must be based on a sound understanding of both ecological and genomic impacts. This opinion synthesizes knowledge about the genomic basis of adaptation in marine species, highlights the few examples where genomic forecasting has been applied in marine systems, identifies the key challenges in validating genomic offset estimates in marine species, and provides a workflow to guide marine managers in incorporating these predictions into the decision-making process.
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- 2024
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12. Ethnic disparities of vascular complications in patients with and without diabetes diagnoses
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Yoshida, Y, primary, Zu, Y, additional, and Fonseca, V, additional
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- 2024
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13. Colorectal neoplastic emergencies in immunocompromised patients: preliminary result from the Web-based International Register of Emergency Surgery and Trauma (WIRES-T trial)
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Coccolini, F, Mazzoni, A, Cremonini, C, Cobuccio, L, Pucciarelli, M, Vetere, G, Borelli, B, Strambi, S, Musetti, S, Miccoli, M, Cremolini, C, Salvetti, F, Fugazzola, P, Ceresoli, M, Elisa, N, Litvin, A, Lostoridis, E, Ahmed, A, Manatakis, D, Negoi, I, Ioannidis, O, Uzunoglu, M, Tochie, J, Cillara, N, Tomadze, G, Bala, M, Isik, A, Fonseca, V, Bellanova, G, Ghannam, W, Yalkin, O, Garcia, F, Altintoprak, F, Hadzhiev, D, Chirica, M, Zese, M, Balalis, D, Cui, Y, Luppi, D, Romeo, L, Muratore, A, Lunghi, E, Yovtchev, Y, Nikolopoulos, I, Omerovic, M, Zizzo, M, Ugoletti, L, Costa, G, Scalzone, R, Perrone, S, Occhionorelli, S, Nardi, M, Gubbiotti, F, Catena, F, Muhtaroglu, A, Scaramuzzo, R, Corte, H, Yanez, C, Zakaria, A, Seretis, C, Gelmini, R, Pappalardo, V, Paratore, F, Sydorchuk, R, Mulita, F, Kara, Y, Toma, E, Vailas, M, Sotiropoulou, M, Benedetti, F, Elbahnasawy, M, Sibilla, M, Martines, G, Goksoy, B, Parini, D, Zaghi, C, Podda, M, Osipov, A, Brisinda, G, Gambino, G, Akhmeteli, L, Doklestic, K, Loncar, Z, Micic, D, Lesevic, I, D'Agostino, F, Garzali, I, Caicedo, Y, Marcela, L, Marin, P, Perivoliotis, K, Ntentas, I, Kuptsov, A, Dimitrov, E, Chowdhury, S, Patel, T, Sartelli, M, Tartaglia, D, Chiarugi, M, Coccolini F., Mazzoni A., Cremonini C., Cobuccio L., Pucciarelli M., Vetere G., Borelli B., Strambi S., Musetti S., Miccoli M., Cremolini C., Salvetti F., Fugazzola P., Ceresoli M., Elisa N. G., Litvin A., Lostoridis E., Ahmed A. Y. Y. M., Manatakis D., Negoi I., Ioannidis O., Uzunoglu M. Y., Tochie J. N., Cillara N., Tomadze G., Bala M., Isik A., Fonseca V. C., Bellanova G., Ghannam W., Yalkin O., Garcia F. H., Altintoprak F., Hadzhiev D., Chirica M., Zese M., Balalis D., Cui Y., Luppi D., Romeo L., Muratore A., Lunghi E. G., Yovtchev Y., Nikolopoulos I., Omerovic M., Zizzo M., Ugoletti L., Costa G., Scalzone R., Perrone S., Occhionorelli S., Nardi M., Gubbiotti F., Catena F., Muhtaroglu A., Scaramuzzo R., Corte H., Yanez C., Zakaria A. D., Seretis C., Gelmini R., Pappalardo V., Paratore F., Sydorchuk R., Mulita F., Kara Y., Toma E. A., Vailas M., Sotiropoulou M., Benedetti F., Elbahnasawy M., Sibilla M. G., Martines G., Goksoy B., Parini D., Zaghi C., Podda M., Osipov A., Brisinda G., Gambino G., Akhmeteli L., Doklestic K., Loncar Z., Micic D., Lesevic I., D'Agostino F., Garzali I. U., Caicedo Y., Marcela L., Marin P. A. G., Perivoliotis K., Ntentas I., Kuptsov A., Dimitrov E., Chowdhury S., Patel T., Sartelli M., Tartaglia D., Chiarugi M., Coccolini, F, Mazzoni, A, Cremonini, C, Cobuccio, L, Pucciarelli, M, Vetere, G, Borelli, B, Strambi, S, Musetti, S, Miccoli, M, Cremolini, C, Salvetti, F, Fugazzola, P, Ceresoli, M, Elisa, N, Litvin, A, Lostoridis, E, Ahmed, A, Manatakis, D, Negoi, I, Ioannidis, O, Uzunoglu, M, Tochie, J, Cillara, N, Tomadze, G, Bala, M, Isik, A, Fonseca, V, Bellanova, G, Ghannam, W, Yalkin, O, Garcia, F, Altintoprak, F, Hadzhiev, D, Chirica, M, Zese, M, Balalis, D, Cui, Y, Luppi, D, Romeo, L, Muratore, A, Lunghi, E, Yovtchev, Y, Nikolopoulos, I, Omerovic, M, Zizzo, M, Ugoletti, L, Costa, G, Scalzone, R, Perrone, S, Occhionorelli, S, Nardi, M, Gubbiotti, F, Catena, F, Muhtaroglu, A, Scaramuzzo, R, Corte, H, Yanez, C, Zakaria, A, Seretis, C, Gelmini, R, Pappalardo, V, Paratore, F, Sydorchuk, R, Mulita, F, Kara, Y, Toma, E, Vailas, M, Sotiropoulou, M, Benedetti, F, Elbahnasawy, M, Sibilla, M, Martines, G, Goksoy, B, Parini, D, Zaghi, C, Podda, M, Osipov, A, Brisinda, G, Gambino, G, Akhmeteli, L, Doklestic, K, Loncar, Z, Micic, D, Lesevic, I, D'Agostino, F, Garzali, I, Caicedo, Y, Marcela, L, Marin, P, Perivoliotis, K, Ntentas, I, Kuptsov, A, Dimitrov, E, Chowdhury, S, Patel, T, Sartelli, M, Tartaglia, D, Chiarugi, M, Coccolini F., Mazzoni A., Cremonini C., Cobuccio L., Pucciarelli M., Vetere G., Borelli B., Strambi S., Musetti S., Miccoli M., Cremolini C., Salvetti F., Fugazzola P., Ceresoli M., Elisa N. G., Litvin A., Lostoridis E., Ahmed A. Y. Y. M., Manatakis D., Negoi I., Ioannidis O., Uzunoglu M. Y., Tochie J. N., Cillara N., Tomadze G., Bala M., Isik A., Fonseca V. C., Bellanova G., Ghannam W., Yalkin O., Garcia F. H., Altintoprak F., Hadzhiev D., Chirica M., Zese M., Balalis D., Cui Y., Luppi D., Romeo L., Muratore A., Lunghi E. G., Yovtchev Y., Nikolopoulos I., Omerovic M., Zizzo M., Ugoletti L., Costa G., Scalzone R., Perrone S., Occhionorelli S., Nardi M., Gubbiotti F., Catena F., Muhtaroglu A., Scaramuzzo R., Corte H., Yanez C., Zakaria A. D., Seretis C., Gelmini R., Pappalardo V., Paratore F., Sydorchuk R., Mulita F., Kara Y., Toma E. A., Vailas M., Sotiropoulou M., Benedetti F., Elbahnasawy M., Sibilla M. G., Martines G., Goksoy B., Parini D., Zaghi C., Podda M., Osipov A., Brisinda G., Gambino G., Akhmeteli L., Doklestic K., Loncar Z., Micic D., Lesevic I., D'Agostino F., Garzali I. U., Caicedo Y., Marcela L., Marin P. A. G., Perivoliotis K., Ntentas I., Kuptsov A., Dimitrov E., Chowdhury S., Patel T., Sartelli M., Tartaglia D., and Chiarugi M.
- Abstract
Association of advanced age, neoplastic disease and immunocompromission (IC) may lead to surgical emergencies. Few data exist about this topic. Present study reports the preliminary data from the WIRES-T trial about patients managed for colorectal neoplastic emergencies in immunocompromised patients. The required data were taken from a prospective observational international register. The study was approved by the Ethical Committee with approval n. 17575; ClinicalTrials.gov Identifier: NCT03643718. 839 patients were collected; 753 (80.7%) with mild–moderate IC and 86 (10.3%) with severe. Median age was 71.9 years and 73 years, respectively, in the two groups. The causes of mild–moderate IC were reported such malignancy (753–100%), diabetes (103–13.7%), malnutrition (26–3.5%) and uremia (1–0.1%), while severe IC causes were steroids treatment (14–16.3%); neutropenia (7–8.1%), malignancy on chemotherapy (71–82.6%). Preoperative risk classification were reported as follow: mild–moderate: ASA 1–14 (1.9%); ASA 2–202 (26.8%); ASA 3–341 (45.3%); ASA 4–84 (11.2%); ASA 5–7 (0.9%); severe group: ASA 1-1 patient (1.2%); ASA 2–16 patients (18.6%); ASA 3–41 patients (47.7%); ASA 4–19 patients (22.1%); ASA 5–3 patients (3.5%); lastly, ASA score was unavailable for 105 cases (13.9%) in mild–moderate group and in 6 cases (6.9%) in severe group. All the patients enrolled underwent urgent/emergency surgery Damage control approach with open abdomen was adopted in 18 patients. Mortality was 5.1% and 12.8%, respectively, in mild–moderate and severe groups. Long-term survival data: in mild–moderate disease-free survival (median, IQR) is 28 (10–91) and in severe IC, it is 21 (10–94). Overall survival (median, IQR) is 44 (18–99) and 26 (20–90) in mild–moderate and severe, respectively; the same is for post-progression survival (median, IQR) 29 (16–81) and 28, respectively. Univariate and multivariate analyses showed as the only factor influencing mortality in mild–moderate and severe IC is
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- 2023
14. Surgeons’ perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts: results from an international survey
- Author
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Cobianchi, L, Piccolo, D, Dal Mas, F, Agnoletti, V, Ansaloni, L, Balch, J, Biffl, W, Butturini, G, Catena, F, Coccolini, F, Denicolai, S, De Simone, B, Frigerio, I, Fugazzola, P, Marseglia, G, Martellucci, J, Modenese, M, Previtali, P, Ruta, F, Venturi, A, Kaafarani, H, Loftus, T, Abbott, K, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Adamovich, D, Agresta, F, Agrusa, A, Akin, E, Alessiani, M, Alexandrino, H, Ali, S, Mihai, V, Almeida, P, Al-Shehari, M, Altomare, M, Amico, F, Ammendola, M, Andreuccetti, J, Anestiadou, E, Angelos, P, Annicchiarico, A, Antonelli, A, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Arvieux, C, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bacchiocchi, G, Bagnoli, C, Bahouth, H, Baili, E, Bains, L, Baiocchi, G, Bala, M, Balague, C, Balalis, D, Baldini, E, Baraket, O, Baral, S, Barone, M, Barranquero, A, Barreras, J, Bass, G, Bayhan, Z, Bellanova, G, Ben-Ishay, O, Bert, F, Bianchi, V, Biancuzzi, H, Bidoli, C, Radulescu, R, Bignell, M, Biloslavo, A, Bini, R, Bissacco, D, Boati, P, Boddaert, G, Bogdanic, B, Bombardini, C, Bonavina, L, Bonomo, L, Bottari, A, Bouliaris, K, Brachini, G, Brillantino, A, Brisinda, G, Bulanauca, M, Buonomo, L, Burcharth, J, Buscemi, S, Calabretto, F, Calini, G, Calu, V, Campanile, F, Dall'Orto, R, Campos-Serra, A, Campostrini, S, Capoglu, R, Carvas, J, Cascella, M, Pattacini, G, Celentano, V, Centonze, D, Ceresoli, M, Chatzipetris, D, Chessa, A, Chiarello, M, Chirica, M, Chooklin, S, Chouliaras, C, Chowdhury, S, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colak, E, Ruiz, E, Conti, L, Coppola, A, De Sa, T, Costa, S, Cozza, V, Curro', G, Dabekaussen, K, D'Acapito, F, Damaskos, D, D'Ambrosio, G, Das, K, Davies, R, De Beaux, A, Fernandez, S, De Luca, A, De Stefano, F, Degrate, L, Demetrashvili, Z, Demetriades, A, Detanac, D, Dezi, A, Di Buono, G, Di Carlo, I, Di Lascio, P, Di Martino, M, Di Saverio, S, Diaconescu, B, Diaz, J, Dibra, R, Dimitrov, E, Dinuzzi, V, Dios-Barbeito, S, Diyani, J, Dogjani, A, Domanin, M, D'Oria, M, Munoz-Cruzado, V, East, B, Ekelund, M, Ekwen, G, Elbaih, A, Elhadi, M, Enninghorst, N, Ernisova, M, Escalera-Antezana, J, Esposito, S, Esposito, G, Estaire, M, Fare, C, Farre, R, Favi, F, Ferrario, L, Vajana, A, Filisetti, C, Fleres, F, Fonseca, V, Forero-Torres, A, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Frassini, S, Frazzetta, G, Pizzocaro, E, Frountzas, M, Gachabayov, M, Galeiras, R, Vazquez, A, Gargarella, S, Garzali, I, Ghannam, W, Ghazi, F, Gillman, L, Gioco, R, Giordano, A, Giordano, L, Giove, C, Giraudo, G, Giuffrida, M, Capponi, M, Gois, E, Gomes, C, Gomes, F, Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Gracia-Roman, R, Graziano, G, Griffiths, E, Guagni, T, Hadzhiev, D, Haidar, M, Hamid, H, Hardcastle, T, Hayati, F, Healey, A, Hecker, A, Hecker, M, Garcia, E, Hodonou, A, Huaman, E, Huerta, M, Ibrahim, A, Ibrahim, B, Ietto, G, Inama, M, Ioannidis, O, Isik, A, Ismail, N, Ismail, A, Jailani, R, Jang, J, Kalfountzos, C, Kalipershad, S, Kaouras, E, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Katsaros, I, Kavalakat, A, Kechagias, A, Kenig, J, Kessel, B, Khan, J, Khokha, V, Kim, J, Kirkpatrick, A, Klappenbach, R, Kluger, Y, Kobe, Y, Lymperis, E, Kok, K, Kong, V, Korkolis, D, Koukoulis, G, Kovacevic, B, Kruger, V, Kryvoruchko, I, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Lapolla, P, Leppaniemi, A, Licari, L, Lisi, G, Litvin, A, Lizarazu, A, Bayo, H, Lohsiriwat, V, Moreira, C, Lostoridis, E, Luna, A, Luppi, D, Machain, V, Maegele, M, Maggiore, D, Magnone, S, Maier, R, Major, P, Manangi, M, Manetti, A, Mantoglu, B, Marafante, C, Mariani, F, Marinis, A, Mariot, E, Martines, G, Perez, A, Martino, C, Mascagni, P, Massalou, D, Massaro, M, Matias-Garcia, B, Mazzarella, G, Mazzarolo, G, Melo, R, Mendoza-Moreno, F, Meric, S, Meyer, J, Miceli, L, Michalopoulos, N, Milana, F, Mingoli, A, Mishra, T, Mohamed, M, Mohamedahmed, A, Mohammed, M, Mohan, R, Moore, E, Morales-Garcia, D, Muhrbeck, M, Mulita, F, Mustafa, S, Muttillo, E, Naimzada, M, Navsaria, P, Negoi, I, Nespoli, L, Nguyen, C, Nidaw, M, Nigri, G, Nikolopoulos, I, O'Connor, D, Ogundipe, H, Oliveri, C, Olmi, S, Ong, E, Orecchia, L, Osipov, A, Othman, M, Pace, M, Pacilli, M, Pagani, L, Palomba, G, Pantalone, D, Panyko, A, Paolillo, C, Papa, M, Papaconstantinou, D, Papadoliopoulou, M, Papadopoulos, A, Papis, D, Pararas, N, Parreira, J, Parry, N, Pata, F, Patel, T, Paterson-Brown, S, Pavone, G, Pecchini, F, Pegoraro, V, Pellino, G, Pelloni, M, Peloso, A, Del Pozo, E, Pereira, R, Pereira, B, Perez, S, Perra, T, Perrone, G, Pesce, A, Petagna, L, Petracca, G, Phupong, V, Picardi, B, Picciariello, A, Piccoli, M, Picetti, E, Pikoulis, E, Pintar, T, Pirozzolo, G, Piscioneri, F, Podda, M, Porcu, A, Privitera, F, Punzo, C, Quaresima, S, Quiodettis, M, Qvist, N, Rahim, R, de Almeida, F, Ramely, R, Rasa, H, Reichert, M, Reinisch-Liese, A, Renne, A, Riccetti, C, Rodriguez-Luna, M, Roizblatt, D, Romanzi, A, Romeo, L, Roscio, F, Rosnelifaizur, R, Rossi, S, Rubiano, A, Ruiz-Ucar, E, Sakakushev, B, Salamea, J, Sall, I, Samarakoon, L, Sammartano, F, Arteaga, A, Sanchez-Cordero, S, Santoanastaso, D, Sartelli, M, Sasia, D, Sato, N, Savchuk, A, Sawyer, R, Scaioli, G, Schizas, D, Sebastiani, S, Seeliger, B, Lohse, H, Seretis, C, Sermonesi, G, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Sidiropoulos, T, Simoes, R, Siragusa, L, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Sopuev, A, Soreide, K, Sovatzidis, A, Stahel, P, Strickland, M, Sultan, M, Sydorchuk, R, Sydorchuk, L, Syed, S, Tallon-Aguilar, L, Tamburini, A, Tamini, N, Tan, E, Tan, J, Tarasconi, A, Tartaglia, N, Tartaglia, G, Tartaglia, D, Taylor, J, Tebala, G, Teuben, M, Theodorou, A, Tolonen, M, Tomasicchio, G, Toro, A, Torre, B, Triantafyllou, T, Trigiante, G, Tripepi, M, Trostchansky, J, Tsekouras, K, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Uchikov, P, Ugarte-Sierra, B, Ukkonen, M, Vailas, M, Vassiliu, P, Vazquez, R, Velmahos, G, Verde, J, Veroux, M, Vigano, J, Vilallonga, R, Visconti, D, Vittori, A, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Woltz, S, Wong, T, Xenaki, S, Yu, B, Yule, S, Zachariah, S, Zacharis, G, Zaghi, C, Zakaria, A, Zambrano, D, Zampitis, N, Zampogna, B, Zanghi, S, Zantedeschi, M, Zapsalis, K, Zattoni, F, Zese, M, Cobianchi L., Piccolo D., Dal Mas F., Agnoletti V., Ansaloni L., Balch J., Biffl W., Butturini G., Catena F., Coccolini F., Denicolai S., De Simone B., Frigerio I., Fugazzola P., Marseglia G., Marseglia G. R., Martellucci J., Modenese M., Previtali P., Ruta F., Venturi A., Kaafarani H. M., Loftus T. J., Abbott K. L., Abdelmalik A., Abebe N. S., Abu-Zidan F., Adam Y. A. Y., Adamou H., Adamovich D. M., Agresta F., Agrusa A., Akin E., Alessiani M., Alexandrino H., Ali S. M., Mihai V. A., Almeida P. M., Al-Shehari M. M., Altomare M., Amico F., Ammendola M., Andreuccetti J., Anestiadou E., Angelos P., Annicchiarico A., Antonelli A., Aparicio-Sanchez D., Ardito A., Argenio G., Arvieux C. C., Askevold I. H., Atanasov B. T., Augustin G., Awad S. S., Bacchiocchi G., Bagnoli C., Bahouth H., Baili E., Bains L., Baiocchi G. L., Bala M., Balague C., Balalis D., Baldini E., Baraket O., Baral S., Barone M., Barranquero A. G., Barreras J. A., Bass G. A., Bayhan Z., Bellanova G., Ben-Ishay O., Bert F., Bianchi V., Biancuzzi H., Bidoli C., Radulescu R. B., Bignell M. B., Biloslavo A., Bini R., Bissacco D., Boati P., Boddaert G., Bogdanic B., Bombardini C., Bonavina L., Bonomo L., Bottari A., Bouliaris K., Brachini G., Brillantino A., Brisinda G., Bulanauca M. M., Buonomo L. A., Burcharth J., Buscemi S., Calabretto F., Calini G., Calu V., Campanile F. C., Dall'Orto R. C., Campos-Serra A., Campostrini S., Capoglu R., Carvas J. M., Cascella M., Pattacini G. C., Celentano V., Centonze D. C., Ceresoli M., Chatzipetris D., Chessa A., Chiarello M. M., Chirica M., Chooklin S., Chouliaras C., Chowdhury S., Cianci P., Cillara N., Cimbanassi S., Cioffi S. P. B., Colak E., Ruiz E. C., Conti L., Coppola A., De Sa T. C., Costa S. D., Cozza V., Curro' G., Dabekaussen K. F. A. -S. A., D'acapito F., Damaskos D., D'ambrosio G., Das K., Davies R. J., De Beaux A. C., Fernandez S. P. L., De Luca A., De Stefano F., Degrate L., Demetrashvili Z., Demetriades A. K., Detanac D. S., Dezi A., Di Buono G., Di Carlo I., Di Lascio P., Di Martino M., Di Saverio S., Diaconescu B., Diaz J. J., Dibra R., Dimitrov E. N., Dinuzzi V. P., Dios-Barbeito S., Diyani J. F. A., Dogjani A., Domanin M., D'Oria M., Munoz-Cruzado V. D., East B., Ekelund M., Ekwen G. T., Elbaih A. H., Elhadi M., Enninghorst N., Ernisova M., Escalera-Antezana J. P., Esposito S., Esposito G., Estaire M., Fare C. N., Farre R., Favi F., Ferrario L., Vajana A. F. T., Filisetti C., Fleres F., Fonseca V. C., Forero-Torres A., Forfori F., Fortuna L., Fradelos E., Fraga G. P., Fransvea P., Frassini S., Frazzetta G., Pizzocaro E., Frountzas M., Gachabayov M., Galeiras R., Vazquez A. A. G., Gargarella S., Garzali I. U., Ghannam W. M., Ghazi F. N., Gillman L. M., Gioco R., Giordano A., Giordano L., Giove C., Giraudo G., Giuffrida M., Capponi M. G., Gois E., Gomes C. A., Gomes F. C., Gonsaga R. A. T., Gonullu E., Goosen J., Goranovic T., Gracia-Roman R., Graziano G. M. P., Griffiths E. A., Guagni T., Hadzhiev D. B., Haidar M. G., Hamid H. K. S., Hardcastle T. C., Hayati F., Healey A. J., Hecker A., Hecker M., Garcia E. F. H., Hodonou A. M., Huaman E. C., Huerta M., Ibrahim A. F., Ibrahim B. M. S., Ietto G., Inama M., Ioannidis O., Isik A., Ismail N., Ismail A. M. H., Jailani R. F., Jang J. Y., Kalfountzos C., Kalipershad S. N. R., Kaouras E., Kaplan L. J., Kara Y., Karamagioli E., Karamarkovia A., Katsaros I., Kavalakat A. J., Kechagias A., Kenig J., Kessel B. J., Khan J. S., Khokha V., Kim J. I., Kirkpatrick A. W., Klappenbach R., Kluger Y., Kobe Y., Lymperis E. K., Kok K. Y. Y., Kong V., Korkolis D. P., Koukoulis G., Kovacevic B., Kruger V. F., Kryvoruchko I. A., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Lapolla P., Leppaniemi A., Licari L., Lisi G., Litvin A., Lizarazu A., Bayo H. L., Lohsiriwat V., Moreira C. C. L., Lostoridis E., Luna A. T., Luppi D., Machain V. G. M., Maegele M., Maggiore D., Magnone S., Maier R. V., Major P., Manangi M., Manetti A., Mantoglu B., Marafante C., Mariani F., Marinis A., Mariot E. A. S., Martines G., Perez A. M., Martino C., Mascagni P., Massalou D., Massaro M., Matias-Garcia B., Mazzarella G., Mazzarolo G., Melo R. B., Mendoza-Moreno F., Meric S., Meyer J., Miceli L., Michalopoulos N. V., Milana F., Mingoli A., Mishra T. S., Mohamed M., Mohamed M. I. E. A., Mohamedahmed A. Y., Mohammed M. J. S., Mohan R., Moore E. E., Morales-Garcia D., Muhrbeck M., Mulita F., Mustafa S. M. S., Muttillo E. M., Naimzada M. D., Navsaria P. H., Negoi I., Nespoli L., Nguyen C., Nidaw M. K., Nigri G., Nikolopoulos I., O'connor D. B., Ogundipe H. D., Oliveri C., Olmi S., Ong E. C. W., Orecchia L., Osipov A. V., Othman M. F., Pace M., Pacilli M., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papa M. V., Papaconstantinou D., Papadoliopoulou M., Papadopoulos A., Papis D., Pararas N., Parreira J. G., Parry N. G., Pata F., Patel T., Paterson-Brown S., Pavone G., Pecchini F., Pegoraro V., Pellino G., Pelloni M., Peloso A., Del Pozo E. P., Pereira R. G., Pereira B. M., Perez A. L., Perez S., Perra T., Perrone G., Pesce A., Petagna L., Petracca G., Phupong V., Picardi B., Picciariello A., Piccoli M., Picetti E., Pikoulis E. P., Pintar T., Pirozzolo G., Piscioneri F., Podda M., Porcu A., Privitera F., Punzo C., Quaresima S., Quiodettis M. A., Qvist N., Rahim R., de Almeida F. R., Ramely R. B., Rasa H. K., Reichert M., Reinisch-Liese A., Renne A., Riccetti C., Rodriguez-Luna M. R., Roizblatt D., Romanzi A., Romeo L., Roscio F. P. M., Rosnelifaizur R. B., Rossi S., Rubiano A. M., Ruiz-Ucar E., Sakakushev B. E., Salamea J. C., Sall I., Samarakoon L. B., Sammartano F., Arteaga A. S., Sanchez-Cordero S., Santoanastaso D. P. M., Sartelli M., Sasia D., Sato N., Savchuk A., Sawyer R. G., Scaioli G., Schizas D., Sebastiani S., Seeliger B., Lohse H. A. S., Seretis C., Sermonesi G., Serradilla-Martin M., Shelat V. G., Shlyapnikov S., Sidiropoulos T., Simoes R. L., Siragusa L., Siribumrungwong B., Slavchev M., Solaini L., Soldini G., Sopuev A., Soreide K., Sovatzidis A., Stahel P. F., Strickland M., Sultan M. A. H., Sydorchuk R., Sydorchuk L., Syed S. M. A. M., Tallon-Aguilar L., Tamburini A. M., Tamini N., Tan E. C. T. H., Tan J. H., Tarasconi A., Tartaglia N., Tartaglia G., Tartaglia D., Taylor J. V., Tebala G. D., Teuben M., Theodorou A., Tolonen M., Tomasicchio G., Toro A., Torre B., Triantafyllou T., Trigiante G. T., Tripepi M., Trostchansky J., Tsekouras K., Turrado-Rodriguez V., Tutino R., Uccelli M., Uchikov P. A., Ugarte-Sierra B., Ukkonen M. T., Vailas M., Vassiliu P. G., Vazquez A. G., Vazquez R. G., Velmahos G., Verde J. E., Verde J. M., Veroux M., Vigano J., Vilallonga R., Visconti D., Vittori A., Waledziak M., Wannatoop T., Widmer L. W., Wilson M. S. J., Woltz S., Wong T. H., Xenaki S., Yu B., Yule S., Zachariah S. K., Zacharis G., Zaghi C., Zakaria A. D., Zambrano D. A., Zampitis N., Zampogna B., Zanghi S., Zantedeschi M., Zapsalis K., Zattoni F., Zese M., Cobianchi, L, Piccolo, D, Dal Mas, F, Agnoletti, V, Ansaloni, L, Balch, J, Biffl, W, Butturini, G, Catena, F, Coccolini, F, Denicolai, S, De Simone, B, Frigerio, I, Fugazzola, P, Marseglia, G, Martellucci, J, Modenese, M, Previtali, P, Ruta, F, Venturi, A, Kaafarani, H, Loftus, T, Abbott, K, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Adamovich, D, Agresta, F, Agrusa, A, Akin, E, Alessiani, M, Alexandrino, H, Ali, S, Mihai, V, Almeida, P, Al-Shehari, M, Altomare, M, Amico, F, Ammendola, M, Andreuccetti, J, Anestiadou, E, Angelos, P, Annicchiarico, A, Antonelli, A, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Arvieux, C, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bacchiocchi, G, Bagnoli, C, Bahouth, H, Baili, E, Bains, L, Baiocchi, G, Bala, M, Balague, C, Balalis, D, Baldini, E, Baraket, O, Baral, S, Barone, M, Barranquero, A, Barreras, J, Bass, G, Bayhan, Z, Bellanova, G, Ben-Ishay, O, Bert, F, Bianchi, V, Biancuzzi, H, Bidoli, C, Radulescu, R, Bignell, M, Biloslavo, A, Bini, R, Bissacco, D, Boati, P, Boddaert, G, Bogdanic, B, Bombardini, C, Bonavina, L, Bonomo, L, Bottari, A, Bouliaris, K, Brachini, G, Brillantino, A, Brisinda, G, Bulanauca, M, Buonomo, L, Burcharth, J, Buscemi, S, Calabretto, F, Calini, G, Calu, V, Campanile, F, Dall'Orto, R, Campos-Serra, A, Campostrini, S, Capoglu, R, Carvas, J, Cascella, M, Pattacini, G, Celentano, V, Centonze, D, Ceresoli, M, Chatzipetris, D, Chessa, A, Chiarello, M, Chirica, M, Chooklin, S, Chouliaras, C, Chowdhury, S, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colak, E, Ruiz, E, Conti, L, Coppola, A, De Sa, T, Costa, S, Cozza, V, Curro', G, Dabekaussen, K, D'Acapito, F, Damaskos, D, D'Ambrosio, G, Das, K, Davies, R, De Beaux, A, Fernandez, S, De Luca, A, De Stefano, F, Degrate, L, Demetrashvili, Z, Demetriades, A, Detanac, D, Dezi, A, Di Buono, G, Di Carlo, I, Di Lascio, P, Di Martino, M, Di Saverio, S, Diaconescu, B, Diaz, J, Dibra, R, Dimitrov, E, Dinuzzi, V, Dios-Barbeito, S, Diyani, J, Dogjani, A, Domanin, M, D'Oria, M, Munoz-Cruzado, V, East, B, Ekelund, M, Ekwen, G, Elbaih, A, Elhadi, M, Enninghorst, N, Ernisova, M, Escalera-Antezana, J, Esposito, S, Esposito, G, Estaire, M, Fare, C, Farre, R, Favi, F, Ferrario, L, Vajana, A, Filisetti, C, Fleres, F, Fonseca, V, Forero-Torres, A, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Frassini, S, Frazzetta, G, Pizzocaro, E, Frountzas, M, Gachabayov, M, Galeiras, R, Vazquez, A, Gargarella, S, Garzali, I, Ghannam, W, Ghazi, F, Gillman, L, Gioco, R, Giordano, A, Giordano, L, Giove, C, Giraudo, G, Giuffrida, M, Capponi, M, Gois, E, Gomes, C, Gomes, F, Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Gracia-Roman, R, Graziano, G, Griffiths, E, Guagni, T, Hadzhiev, D, Haidar, M, Hamid, H, Hardcastle, T, Hayati, F, Healey, A, Hecker, A, Hecker, M, Garcia, E, Hodonou, A, Huaman, E, Huerta, M, Ibrahim, A, Ibrahim, B, Ietto, G, Inama, M, Ioannidis, O, Isik, A, Ismail, N, Ismail, A, Jailani, R, Jang, J, Kalfountzos, C, Kalipershad, S, Kaouras, E, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Katsaros, I, Kavalakat, A, Kechagias, A, Kenig, J, Kessel, B, Khan, J, Khokha, V, Kim, J, Kirkpatrick, A, Klappenbach, R, Kluger, Y, Kobe, Y, Lymperis, E, Kok, K, Kong, V, Korkolis, D, Koukoulis, G, Kovacevic, B, Kruger, V, Kryvoruchko, I, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Lapolla, P, Leppaniemi, A, Licari, L, Lisi, G, Litvin, A, Lizarazu, A, Bayo, H, Lohsiriwat, V, Moreira, C, Lostoridis, E, Luna, A, Luppi, D, Machain, V, Maegele, M, Maggiore, D, Magnone, S, Maier, R, Major, P, Manangi, M, Manetti, A, Mantoglu, B, Marafante, C, Mariani, F, Marinis, A, Mariot, E, Martines, G, Perez, A, Martino, C, Mascagni, P, Massalou, D, Massaro, M, Matias-Garcia, B, Mazzarella, G, Mazzarolo, G, Melo, R, Mendoza-Moreno, F, Meric, S, Meyer, J, Miceli, L, Michalopoulos, N, Milana, F, Mingoli, A, Mishra, T, Mohamed, M, Mohamedahmed, A, Mohammed, M, Mohan, R, Moore, E, Morales-Garcia, D, Muhrbeck, M, Mulita, F, Mustafa, S, Muttillo, E, Naimzada, M, Navsaria, P, Negoi, I, Nespoli, L, Nguyen, C, Nidaw, M, Nigri, G, Nikolopoulos, I, O'Connor, D, Ogundipe, H, Oliveri, C, Olmi, S, Ong, E, Orecchia, L, Osipov, A, Othman, M, Pace, M, Pacilli, M, Pagani, L, Palomba, G, Pantalone, D, Panyko, A, Paolillo, C, Papa, M, Papaconstantinou, D, Papadoliopoulou, M, Papadopoulos, A, Papis, D, Pararas, N, Parreira, J, Parry, N, Pata, F, Patel, T, Paterson-Brown, S, Pavone, G, Pecchini, F, Pegoraro, V, Pellino, G, Pelloni, M, Peloso, A, Del Pozo, E, Pereira, R, Pereira, B, Perez, S, Perra, T, Perrone, G, Pesce, A, Petagna, L, Petracca, G, Phupong, V, Picardi, B, Picciariello, A, Piccoli, M, Picetti, E, Pikoulis, E, Pintar, T, Pirozzolo, G, Piscioneri, F, Podda, M, Porcu, A, Privitera, F, Punzo, C, Quaresima, S, Quiodettis, M, Qvist, N, Rahim, R, de Almeida, F, Ramely, R, Rasa, H, Reichert, M, Reinisch-Liese, A, Renne, A, Riccetti, C, Rodriguez-Luna, M, Roizblatt, D, Romanzi, A, Romeo, L, Roscio, F, Rosnelifaizur, R, Rossi, S, Rubiano, A, Ruiz-Ucar, E, Sakakushev, B, Salamea, J, Sall, I, Samarakoon, L, Sammartano, F, Arteaga, A, Sanchez-Cordero, S, Santoanastaso, D, Sartelli, M, Sasia, D, Sato, N, Savchuk, A, Sawyer, R, Scaioli, G, Schizas, D, Sebastiani, S, Seeliger, B, Lohse, H, Seretis, C, Sermonesi, G, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Sidiropoulos, T, Simoes, R, Siragusa, L, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Sopuev, A, Soreide, K, Sovatzidis, A, Stahel, P, Strickland, M, Sultan, M, Sydorchuk, R, Sydorchuk, L, Syed, S, Tallon-Aguilar, L, Tamburini, A, Tamini, N, Tan, E, Tan, J, Tarasconi, A, Tartaglia, N, Tartaglia, G, Tartaglia, D, Taylor, J, Tebala, G, Teuben, M, Theodorou, A, Tolonen, M, Tomasicchio, G, Toro, A, Torre, B, Triantafyllou, T, Trigiante, G, Tripepi, M, Trostchansky, J, Tsekouras, K, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Uchikov, P, Ugarte-Sierra, B, Ukkonen, M, Vailas, M, Vassiliu, P, Vazquez, R, Velmahos, G, Verde, J, Veroux, M, Vigano, J, Vilallonga, R, Visconti, D, Vittori, A, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Woltz, S, Wong, T, Xenaki, S, Yu, B, Yule, S, Zachariah, S, Zacharis, G, Zaghi, C, Zakaria, A, Zambrano, D, Zampitis, N, Zampogna, B, Zanghi, S, Zantedeschi, M, Zapsalis, K, Zattoni, F, Zese, M, Cobianchi L., Piccolo D., Dal Mas F., Agnoletti V., Ansaloni L., Balch J., Biffl W., Butturini G., Catena F., Coccolini F., Denicolai S., De Simone B., Frigerio I., Fugazzola P., Marseglia G., Marseglia G. R., Martellucci J., Modenese M., Previtali P., Ruta F., Venturi A., Kaafarani H. M., Loftus T. J., Abbott K. L., Abdelmalik A., Abebe N. S., Abu-Zidan F., Adam Y. A. Y., Adamou H., Adamovich D. M., Agresta F., Agrusa A., Akin E., Alessiani M., Alexandrino H., Ali S. M., Mihai V. A., Almeida P. M., Al-Shehari M. M., Altomare M., Amico F., Ammendola M., Andreuccetti J., Anestiadou E., Angelos P., Annicchiarico A., Antonelli A., Aparicio-Sanchez D., Ardito A., Argenio G., Arvieux C. C., Askevold I. H., Atanasov B. T., Augustin G., Awad S. S., Bacchiocchi G., Bagnoli C., Bahouth H., Baili E., Bains L., Baiocchi G. L., Bala M., Balague C., Balalis D., Baldini E., Baraket O., Baral S., Barone M., Barranquero A. G., Barreras J. A., Bass G. A., Bayhan Z., Bellanova G., Ben-Ishay O., Bert F., Bianchi V., Biancuzzi H., Bidoli C., Radulescu R. B., Bignell M. B., Biloslavo A., Bini R., Bissacco D., Boati P., Boddaert G., Bogdanic B., Bombardini C., Bonavina L., Bonomo L., Bottari A., Bouliaris K., Brachini G., Brillantino A., Brisinda G., Bulanauca M. M., Buonomo L. A., Burcharth J., Buscemi S., Calabretto F., Calini G., Calu V., Campanile F. C., Dall'Orto R. C., Campos-Serra A., Campostrini S., Capoglu R., Carvas J. M., Cascella M., Pattacini G. C., Celentano V., Centonze D. C., Ceresoli M., Chatzipetris D., Chessa A., Chiarello M. M., Chirica M., Chooklin S., Chouliaras C., Chowdhury S., Cianci P., Cillara N., Cimbanassi S., Cioffi S. P. B., Colak E., Ruiz E. C., Conti L., Coppola A., De Sa T. C., Costa S. D., Cozza V., Curro' G., Dabekaussen K. F. A. -S. A., D'acapito F., Damaskos D., D'ambrosio G., Das K., Davies R. J., De Beaux A. C., Fernandez S. P. L., De Luca A., De Stefano F., Degrate L., Demetrashvili Z., Demetriades A. K., Detanac D. S., Dezi A., Di Buono G., Di Carlo I., Di Lascio P., Di Martino M., Di Saverio S., Diaconescu B., Diaz J. J., Dibra R., Dimitrov E. N., Dinuzzi V. P., Dios-Barbeito S., Diyani J. F. A., Dogjani A., Domanin M., D'Oria M., Munoz-Cruzado V. D., East B., Ekelund M., Ekwen G. T., Elbaih A. H., Elhadi M., Enninghorst N., Ernisova M., Escalera-Antezana J. P., Esposito S., Esposito G., Estaire M., Fare C. N., Farre R., Favi F., Ferrario L., Vajana A. F. T., Filisetti C., Fleres F., Fonseca V. C., Forero-Torres A., Forfori F., Fortuna L., Fradelos E., Fraga G. P., Fransvea P., Frassini S., Frazzetta G., Pizzocaro E., Frountzas M., Gachabayov M., Galeiras R., Vazquez A. A. G., Gargarella S., Garzali I. U., Ghannam W. M., Ghazi F. N., Gillman L. M., Gioco R., Giordano A., Giordano L., Giove C., Giraudo G., Giuffrida M., Capponi M. G., Gois E., Gomes C. A., Gomes F. C., Gonsaga R. A. T., Gonullu E., Goosen J., Goranovic T., Gracia-Roman R., Graziano G. M. P., Griffiths E. A., Guagni T., Hadzhiev D. B., Haidar M. G., Hamid H. K. S., Hardcastle T. C., Hayati F., Healey A. J., Hecker A., Hecker M., Garcia E. F. H., Hodonou A. M., Huaman E. C., Huerta M., Ibrahim A. F., Ibrahim B. M. S., Ietto G., Inama M., Ioannidis O., Isik A., Ismail N., Ismail A. M. H., Jailani R. F., Jang J. Y., Kalfountzos C., Kalipershad S. N. R., Kaouras E., Kaplan L. J., Kara Y., Karamagioli E., Karamarkovia A., Katsaros I., Kavalakat A. J., Kechagias A., Kenig J., Kessel B. J., Khan J. S., Khokha V., Kim J. I., Kirkpatrick A. W., Klappenbach R., Kluger Y., Kobe Y., Lymperis E. K., Kok K. Y. Y., Kong V., Korkolis D. P., Koukoulis G., Kovacevic B., Kruger V. F., Kryvoruchko I. A., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Lapolla P., Leppaniemi A., Licari L., Lisi G., Litvin A., Lizarazu A., Bayo H. L., Lohsiriwat V., Moreira C. C. L., Lostoridis E., Luna A. T., Luppi D., Machain V. G. M., Maegele M., Maggiore D., Magnone S., Maier R. V., Major P., Manangi M., Manetti A., Mantoglu B., Marafante C., Mariani F., Marinis A., Mariot E. A. S., Martines G., Perez A. M., Martino C., Mascagni P., Massalou D., Massaro M., Matias-Garcia B., Mazzarella G., Mazzarolo G., Melo R. B., Mendoza-Moreno F., Meric S., Meyer J., Miceli L., Michalopoulos N. V., Milana F., Mingoli A., Mishra T. S., Mohamed M., Mohamed M. I. E. A., Mohamedahmed A. Y., Mohammed M. J. S., Mohan R., Moore E. E., Morales-Garcia D., Muhrbeck M., Mulita F., Mustafa S. M. S., Muttillo E. M., Naimzada M. D., Navsaria P. H., Negoi I., Nespoli L., Nguyen C., Nidaw M. K., Nigri G., Nikolopoulos I., O'connor D. B., Ogundipe H. D., Oliveri C., Olmi S., Ong E. C. W., Orecchia L., Osipov A. V., Othman M. F., Pace M., Pacilli M., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papa M. V., Papaconstantinou D., Papadoliopoulou M., Papadopoulos A., Papis D., Pararas N., Parreira J. G., Parry N. G., Pata F., Patel T., Paterson-Brown S., Pavone G., Pecchini F., Pegoraro V., Pellino G., Pelloni M., Peloso A., Del Pozo E. P., Pereira R. G., Pereira B. M., Perez A. L., Perez S., Perra T., Perrone G., Pesce A., Petagna L., Petracca G., Phupong V., Picardi B., Picciariello A., Piccoli M., Picetti E., Pikoulis E. P., Pintar T., Pirozzolo G., Piscioneri F., Podda M., Porcu A., Privitera F., Punzo C., Quaresima S., Quiodettis M. A., Qvist N., Rahim R., de Almeida F. R., Ramely R. B., Rasa H. K., Reichert M., Reinisch-Liese A., Renne A., Riccetti C., Rodriguez-Luna M. R., Roizblatt D., Romanzi A., Romeo L., Roscio F. P. M., Rosnelifaizur R. B., Rossi S., Rubiano A. M., Ruiz-Ucar E., Sakakushev B. E., Salamea J. C., Sall I., Samarakoon L. B., Sammartano F., Arteaga A. S., Sanchez-Cordero S., Santoanastaso D. P. M., Sartelli M., Sasia D., Sato N., Savchuk A., Sawyer R. G., Scaioli G., Schizas D., Sebastiani S., Seeliger B., Lohse H. A. S., Seretis C., Sermonesi G., Serradilla-Martin M., Shelat V. G., Shlyapnikov S., Sidiropoulos T., Simoes R. L., Siragusa L., Siribumrungwong B., Slavchev M., Solaini L., Soldini G., Sopuev A., Soreide K., Sovatzidis A., Stahel P. F., Strickland M., Sultan M. A. H., Sydorchuk R., Sydorchuk L., Syed S. M. A. M., Tallon-Aguilar L., Tamburini A. M., Tamini N., Tan E. C. T. H., Tan J. H., Tarasconi A., Tartaglia N., Tartaglia G., Tartaglia D., Taylor J. V., Tebala G. D., Teuben M., Theodorou A., Tolonen M., Tomasicchio G., Toro A., Torre B., Triantafyllou T., Trigiante G. T., Tripepi M., Trostchansky J., Tsekouras K., Turrado-Rodriguez V., Tutino R., Uccelli M., Uchikov P. A., Ugarte-Sierra B., Ukkonen M. T., Vailas M., Vassiliu P. G., Vazquez A. G., Vazquez R. G., Velmahos G., Verde J. E., Verde J. M., Veroux M., Vigano J., Vilallonga R., Visconti D., Vittori A., Waledziak M., Wannatoop T., Widmer L. W., Wilson M. S. J., Woltz S., Wong T. H., Xenaki S., Yu B., Yule S., Zachariah S. K., Zacharis G., Zaghi C., Zakaria A. D., Zambrano D. A., Zampitis N., Zampogna B., Zanghi S., Zantedeschi M., Zapsalis K., Zattoni F., and Zese M.
- Abstract
Background: Artificial intelligence (AI) is gaining traction in medicine and surgery. AI-based applications can offer tools to examine high-volume data to inform predictive analytics that supports complex decision-making processes. Time-sensitive trauma and emergency contexts are often challenging. The study aims to investigate trauma and emergency surgeons’ knowledge and perception of using AI-based tools in clinical decision-making processes. Methods: An online survey grounded on literature regarding AI-enabled surgical decision-making aids was created by a multidisciplinary committee and endorsed by the World Society of Emergency Surgery (WSES). The survey was advertised to 917 WSES members through the society’s website and Twitter profile. Results: 650 surgeons from 71 countries in five continents participated in the survey. Results depict the presence of technology enthusiasts and skeptics and surgeons’ preference toward more classical decision-making aids like clinical guidelines, traditional training, and the support of their multidisciplinary colleagues. A lack of knowledge about several AI-related aspects emerges and is associated with mistrust. Discussion: The trauma and emergency surgical community is divided into those who firmly believe in the potential of AI and those who do not understand or trust AI-enabled surgical decision-making aids. Academic societies and surgical training programs should promote a foundational, working knowledge of clinical AI.
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- 2023
15. Acute diverticulitis in immunocompromised patients: evidence from an international multicenter observational registry (Web-based International Register of Emergency Surgery and Trauma, Wires-T)
- Author
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Tartaglia, D, Cremonini, C, Annunziata, E, Catena, F, Sartelli, M, Kirkpatrick, A, Musetti, S, Strambi, S, Chiarugi, M, Coccolini, F, Salvetti, F, Fugazzola, P, Ceresoli, M, Benedetti, F, Elisa, N, Litvin, A, Lostoridis, E, Ahmed, A, Manatakis, D, Negoi, I, Ioannidis, O, Uzunoglu, M, Tochie, J, Cillara, N, Tomadze, G, Bala, M, Isik, A, Fonseca, V, Bellanova, G, Ghannam, W, Yalkin, O, Garcia, F, Altintoprak, F, Hadzhiev, D, Chirica, M, Zese, M, Balalis, D, Cui, Y, Luppi, D, Romeo, L, Muratore, A, Lunghi, E, Yovtchev, Y, Dimitrov, E, Nikolopoulos, I, Omerovic, M, Zizzo, M, Ugoletti, L, Costa, G, Scalzone, R, Perrone, S, Occhionorelli, S, Nardi, M, Gubbiotti, F, Muhtaroglu, A, Scaramuzzo, R, Corte, H, Yanez, C, Zakaria, A, Seretis, C, Gelmini, R, Pappalardo, V, Paratore, F, Sydorchuk, R, Mulita, F, Kara, Y, Toma, E, Vailas, M, Sotiropoulou, M, Elbahnasawy, M, Sibilla, M, Martines, G, Goksoy, B, Parini, D, Zaghi, C, Podda, M, Osipov, A, Brisinda, G, Gambino, G, Doklestic, L, Loncar, Z, Micic, D, Lesevic, I, D'Agostino, F, Garzali, I, Caicedo, Y, Marcela, L, Marin, P, Perivoliotis, K, Ntentas, I, Kuptsov, A, Chowdhury, S, Patel, T, Tartaglia D., Cremonini C., Annunziata E., Catena F., Sartelli M., Kirkpatrick A. W., Musetti S., Strambi S., Chiarugi M., Coccolini F., Salvetti F., Fugazzola P., Ceresoli M., Benedetti F., Elisa N. G., Litvin A., Lostoridis E., Ahmed A. Y. Y. M., Manatakis D., Negoi I., Ioannidis O., Uzunoglu M. Y., Tochie J. N., Cillara N., Tomadze G., Bala M., Isik A., Fonseca V. C., Bellanova G., Ghannam W., Yalkin O., Garcia F. H., Altintoprak F., Hadzhiev D., Chirica M., Zese M., Balalis D., Cui Y., Luppi D., Romeo L., Muratore A., Lunghi E. G., Yovtchev Y., Dimitrov E., Nikolopoulos I., Omerovic M., Zizzo M., Ugoletti L., Costa G., Scalzone R., Perrone S., Occhionorelli S., Nardi M., Gubbiotti F., Muhtaroglu A., Scaramuzzo R., Corte H., Yanez C., Zakaria A. D., Seretis C., Gelmini R., Pappalardo V., Paratore F., Sydorchuk R., Mulita F., Kara Y., Toma E. A., Vailas M., Sotiropoulou M., Elbahnasawy M., Sibilla M. G., Martines G., Goksoy B., Parini D., Zaghi C., Podda M., Osipov A., Brisinda G., Gambino G., Doklestic L. A. K., Loncar Z., Micic D., Lesevic I., D'Agostino F., Garzali I. U., Caicedo Y., Marcela L., Marin P. A. G., Perivoliotis K., Ntentas I., Kuptsov A., Chowdhury S., Patel T., Tartaglia, D, Cremonini, C, Annunziata, E, Catena, F, Sartelli, M, Kirkpatrick, A, Musetti, S, Strambi, S, Chiarugi, M, Coccolini, F, Salvetti, F, Fugazzola, P, Ceresoli, M, Benedetti, F, Elisa, N, Litvin, A, Lostoridis, E, Ahmed, A, Manatakis, D, Negoi, I, Ioannidis, O, Uzunoglu, M, Tochie, J, Cillara, N, Tomadze, G, Bala, M, Isik, A, Fonseca, V, Bellanova, G, Ghannam, W, Yalkin, O, Garcia, F, Altintoprak, F, Hadzhiev, D, Chirica, M, Zese, M, Balalis, D, Cui, Y, Luppi, D, Romeo, L, Muratore, A, Lunghi, E, Yovtchev, Y, Dimitrov, E, Nikolopoulos, I, Omerovic, M, Zizzo, M, Ugoletti, L, Costa, G, Scalzone, R, Perrone, S, Occhionorelli, S, Nardi, M, Gubbiotti, F, Muhtaroglu, A, Scaramuzzo, R, Corte, H, Yanez, C, Zakaria, A, Seretis, C, Gelmini, R, Pappalardo, V, Paratore, F, Sydorchuk, R, Mulita, F, Kara, Y, Toma, E, Vailas, M, Sotiropoulou, M, Elbahnasawy, M, Sibilla, M, Martines, G, Goksoy, B, Parini, D, Zaghi, C, Podda, M, Osipov, A, Brisinda, G, Gambino, G, Doklestic, L, Loncar, Z, Micic, D, Lesevic, I, D'Agostino, F, Garzali, I, Caicedo, Y, Marcela, L, Marin, P, Perivoliotis, K, Ntentas, I, Kuptsov, A, Chowdhury, S, Patel, T, Tartaglia D., Cremonini C., Annunziata E., Catena F., Sartelli M., Kirkpatrick A. W., Musetti S., Strambi S., Chiarugi M., Coccolini F., Salvetti F., Fugazzola P., Ceresoli M., Benedetti F., Elisa N. G., Litvin A., Lostoridis E., Ahmed A. Y. Y. M., Manatakis D., Negoi I., Ioannidis O., Uzunoglu M. Y., Tochie J. N., Cillara N., Tomadze G., Bala M., Isik A., Fonseca V. C., Bellanova G., Ghannam W., Yalkin O., Garcia F. H., Altintoprak F., Hadzhiev D., Chirica M., Zese M., Balalis D., Cui Y., Luppi D., Romeo L., Muratore A., Lunghi E. G., Yovtchev Y., Dimitrov E., Nikolopoulos I., Omerovic M., Zizzo M., Ugoletti L., Costa G., Scalzone R., Perrone S., Occhionorelli S., Nardi M., Gubbiotti F., Muhtaroglu A., Scaramuzzo R., Corte H., Yanez C., Zakaria A. D., Seretis C., Gelmini R., Pappalardo V., Paratore F., Sydorchuk R., Mulita F., Kara Y., Toma E. A., Vailas M., Sotiropoulou M., Elbahnasawy M., Sibilla M. G., Martines G., Goksoy B., Parini D., Zaghi C., Podda M., Osipov A., Brisinda G., Gambino G., Doklestic L. A. K., Loncar Z., Micic D., Lesevic I., D'Agostino F., Garzali I. U., Caicedo Y., Marcela L., Marin P. A. G., Perivoliotis K., Ntentas I., Kuptsov A., Chowdhury S., and Patel T.
- Abstract
Background: Immunocompromised patients with acute diverticulitis are at increased risk of morbidity and mortality. The aim of this study was to compare clinical presentations, types of treatment, and outcomes between immunocompromised and immunocompetent patients with acute diverticulitis. Methods: We compared the data of patients with acute diverticulitis extracted from the Web-based International Registry of Emergency Surgery and Trauma (WIRES-T) from January 2018 to December 2021. First, two groups were identified: medical therapy (A) and surgical therapy (B). Each group was divided into three subgroups: nonimmunocompromised (grade 0), mildly to moderately (grade 1), and severely immunocompromised (grade 2). Results: Data from 482 patients were analyzed—229 patients (47.5%) [M:F = 1:1; median age: 60 (24–95) years] in group A and 253 patients (52.5%) [M:F = 1:1; median age: 71 (26–94) years] in group B. There was a significant difference between the two groups in grade distribution: 69.9% versus 38.3% for grade 0, 26.6% versus 51% for grade 1, and 3.5% versus 10.7% for grade 2 (p < 0.00001). In group A, severe sepsis (p = 0.027) was more common in higher grades of immunodeficiency. Patients with grade 2 needed longer hospitalization (p = 0.005). In group B, a similar condition was found in terms of severe sepsis (p = 0.002), quick Sequential Organ Failure Assessment score > 2 (p = 0.0002), and Mannheim Peritonitis Index (p = 0.010). A Hartmann’s procedure is mainly performed in grades 1–2 (p < 0.0001). Major complications increased significantly after a Hartmann’s procedure (p = 0.047). Mortality was higher in the immunocompromised patients (p = 0.002). Conclusions: Immunocompromised patients with acute diverticulitis present with a more severe clinical picture. When surgery is required, immunocompromised patients mainly undergo a Hartmann’s procedure. Postoperative morbidity and mortality are, however, higher in immunocompromised patients, who also requ
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- 2023
16. Time for a paradigm shift in shared decision-making in trauma and emergency surgery? Results from an international survey
- Author
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Cobianchi, L, Dal Mas, F, Agnoletti, V, Ansaloni, L, Biffl, W, Butturini, G, Campostrini, S, Catena, F, Denicolai, S, Fugazzola, P, Martellucci, J, Massaro, M, Previtali, P, Ruta, F, Venturi, A, Woltz, S, Kaafarani, H, Loftus, T, Aapoaylu, R, Abbott, K, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Adamovich, D, Agresta, F, Agrusa, A, Akin, E, Alessiani, M, Alexandrino, H, Bidoli, C, Ali, S, Mihai, V, Almeida, P, Al-Shehari, M, Altomare, M, Amico, F, Ammendola, M, Andreuccetti, J, Anestiadou, E, Annicchiarico, A, Antonelli, A, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Arvieux, C, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bacchiocchi, G, Bagnoli, C, Bahouth, H, Baili, E, Bains, L, Baiocchi, G, Bala, M, Balaguacopyright, C, Balalis, D, Baldini, E, Baraket, O, Baral, S, Barone, M, Gonzalez Barranquero, A, Barreras, J, Bass, G, Bayhan, Z, Bellanova, G, Ben-Ishay, O, Bert, F, Bianchi, V, Biancuzzi, H, Radulescu, R, Bignell, M, Biloslavo, A, Bini, R, Bissacco, D, Boati, P, Boddaert, G, Bogdanic, B, Bombardini, C, Bonavina, L, Bonomo, L, Bottari, A, Bouliaris, K, Brachini, G, Brillantino, A, Brisinda, G, Bulanauca, M, Buonomo, L, Burcharth, J, Buscemi, S, Calabretto, F, Calini, G, Calu, V, Campanile, F, Campo Dall'Orto, R, Campos-Serra, A, Carvas, J, Cascella, M, Pattacini, G, Celentano, V, Centonze, D, Ceresoli, M, Chatzipetris, D, Chessa, A, Chiarello, M, Chirica, M, Chooklin, S, Chouliaras, C, Chowdhury, S, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colais-Ruiz, E, Colak, E, Conti, L, Coppola, A, de Sa, T, Costa, S, Cozza, V, Curro', G, Dabekaussen, K, D'Acapito, F, Damaskos, D, D'Ambrosio, G, Das, K, Davies, R, de Beaux, A, De Lebrusant Fernandez, S, De Luca, A, De Simone, B, De Stefano, F, Degrate, L, Demetrashvili, Z, Demetriades, A, Detanac, D, Dezi, A, Di Buono, G, Carlo, I, Di Lascio, P, Di Martino, M, Di Saverio, S, Diaconescu, B, Diaz, J, Dibra, R, Dimitrov, E, Dinuzzi, V, Dios-Barbeito, S, Diyani, J, Dogjani, A, Domanin, M, D'Oria, M, Munoz-Cruzado, V, East, B, Ekelund, M, Ekwen, G, Elbaih, A, Elhadi, M, Enninghorst, N, Ernisova, M, Escalera-Antezana, J, Esposito, S, Esposito, G, Estaire-Gamez, M, Fara, C, Farre, R, Favi, F, Ferrario, L, Ferrario di Tor Vajana, A, Filisetti, C, Fleres, F, Fonseca, V, Forero-Torres, A, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Frassini, S, Frazzetta, G, Frigerio, I, Frountzas, M, Gachabayov, M, Galeiras, R, Garcaa, B, Garcia Vazquez, A, Gargarella, S, Garzali, I, Ghannam, W, Ghazi, F, Gillman, L, Gioco, R, Giordano, A, Giordano, L, Giove, C, Giraudo, G, Giuffrida, M, Capponi, M, Gois, E, Gomes, C, Gomes, F, Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Gracia-Roman, R, Graziano, G, Griffiths, E, Guagni, T, Hadzhiev, D, Haidar, M, Hamid, H, Hardcastle, T, Hayati, F, Healey, A, Hecker, A, Hecker, M, Garcia, E, Hodonou, A, Huaman, E, Huerta, M, Ibrahim, A, Ibrahim, B, Ietto, G, Inama, M, Ioannidis, O, Isik, A, Ismail, N, Ismail, A, Jailani, R, Jang, J, Kalfountzos, C, Kalipershad, S, Kaouras, E, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Katsaros, I, Kavalakat, A, Kechagias, A, Kenig, J, Kessel, B, Khan, J, Khokha, V, Kim, J, Kirkpatrick, A, Klappenbach, R, Kobe, Y, Lymperis, E, Kok, K, Kong, V, Korkolis, D, Koukoulis, G, Kovacevic, B, Kruger, V, Kryvoruchko, I, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Lapolla, P, Licari, L, Lisi, G, Litvin, A, Lizarazu, A, Bayo, H, Lohsiriwat, V, Moreira, C, Lostoridis, E, Luna, A, Luppi, D, V, G, Maegele, M, Maggiore, D, Magnone, S, Maier, R, Major, P, Manangi, M, Manetti, A, Mantoglu, B, Marafante, C, Mariani, F, Marinis, A, Mariot, E, Marseglia, G, Martanez-Parez, A, Martines, G, Perez, A, Martino, C, Mascagni, P, Massalou, D, Mataas-Garcaa, B, Mazzarella, G, Mazzarolo, G, Melo, R, Mendoza-Moreno, F, Meric, S, Meyer, J, Miceli, L, Michalopoulos, N, Milana, F, Mingoli, A, Mishra, T, Mohamed, M, Mohamedahmed, A, Mohammed, M, Mohan, R, Moore, E, Morales-Garcia, D, Muhrbeck, M, Mulita, F, Mustafa, S, Muttillo, E, Naimzada, M, Navsaria, P, Negoi, I, Nespoli, L, Nguyen, C, Nidaw, M, Nigri, G, Nikolopoulos, I, O'Connor, D, Ogundipe, H, Oliveri, C, Olmi, S, Ong, E, Orecchia, L, Osipov, A, Othman, M, Pace, M, Pacilli, M, Pagani, L, Palomba, G, Pantalone, D, Panyko, A, Paolillo, C, Papa, M, Papaconstantinou, D, Papadoliopoulou, M, Papadopoulos, A, Papis, D, Pararas, N, Parreira, J, Parry, N, Pata, F, Patel, T, Paterson-Brown, S, Pavone, G, Pecchini, F, Pellino, G, Pelloni, M, Peloso, A, del Pozo, E, Pereira, R, Pereira, B, Perra, T, Perrone, G, Pesce, A, Petagna, L, Petracca, G, Phupong, V, Picardi, B, Picciariello, A, Piccoli, M, Piccolo, D, Picetti, E, Pikoulis Pikoulis, E, Pintar, T, Pirozzolo, G, Piscioneri, F, Podda, M, Porcu, A, Privitera, F, Punzo, C, Quaresima, S, Quiodettis, M, Qvist, N, Rahim, R, de Almeida, F, Ramely, R, Rasa, H, Reichert, M, Reinisch-Liese, A, Renne, A, Riccetti, C, Rodriguez-Luna, M, Roizblatt, D, Romanzi, A, Romeo, L, Roscio, F, Rosnelifaizur, R, Rossi, S, Rubiano, A, Ruiz-Ascar, E, Sakakushev, B, Salamea, J, Sall, I, Samarakoon, L, Sammartano, F, Arteaga, A, Sanchez-Cordero, S, Santoanastaso, D, Sasia, D, Sato, N, Savchuk, A, Sawyer, R, Scaioli, G, Schizas, D, Sebastiani, S, Seeliger, B, Lohse, H, Seretis, C, Sermonesi, G, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Sidiropoulos, T, Simoes, R, Siragusa, L, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Sopuev, A, Soreide, K, Sovatzidis, A, Stahel, P, Strickland, M, Sultan, M, Sydorchuk, R, Sydorchuk, L, Syed, S, Syed, A, Tallon-Aguilar, L, Tamburini, A, Tamini, N, Tan, E, Tan, J, Tarasconi, A, Tartaglia, N, Tartaglia, G, Tartaglia, D, Taylor, J, Tebala, G, Teuben, M, Theodorou, A, Tolonen, M, Tomasicchio, G, Toro, A, Torre, B, Triantafyllou, T, Trigiante Trigiante, G, Tripepi, M, Trostchansky, J, Tsekouras, K, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Uchikov, P, Ugarte-Sierra, B, Ukkonen, M, Vailas, M, Vassiliu, P, Vazquez, A, Vazquez, R, Verde, J, Veroux, M, Vigano, J, Vilallonga, R, Visconti, D, Vittori, A, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Wong, T, Xenaki, S, Yu, B, Yule, S, Zachariah, S, Zacharis, G, Zaghi, C, Zakaria, A, Zambrano, D, Zampitis, N, Zampogna, B, Zangha, S, Zapsalis, K, Zattoni, F, Zese, M, Farre, S, Pegoraro, V, Zantedeschi, M, Reitano, E, Pizzocaro, E, Cobianchi L., Dal Mas F., Agnoletti V., Ansaloni L., Biffl W., Butturini G., Campostrini S., Catena F., Denicolai S., Fugazzola P., Martellucci J., Massaro M., Previtali P., Ruta F., Venturi A., Woltz S., Kaafarani H. M., Loftus T. J., Aapoaylu R., Abbott K. L., Abdelmalik A., Abebe N. S., Abu-Zidan F., Adam Y. A. Y., Adamou H., Adamovich D. M., Agresta F., Agrusa A., Akin E., Alessiani M., Alexandrino H., Bidoli C., Ali S. M., Mihai V. A., Almeida P. M., Al-Shehari M. M., Altomare M., Amico F., Ammendola M., Andreuccetti J., Anestiadou E., Annicchiarico A., Antonelli A., Aparicio-Sanchez D., Ardito A., Argenio G., Arvieux C. C., Arvieux C., Askevold I. H., Atanasov B. T., Augustin G., Awad S. S., Bacchiocchi G., Bagnoli C., Bahouth H., Baili E., Bains L., Baiocchi G. L., Bala M., BalaguaCopyright C., Balalis D., Baldini E., Baraket O., Baral S., Barone M., Gonzalez Barranquero A., Barreras J. A., Bass G. A., Bayhan Z., Bellanova G., Ben-Ishay O., Bert F., Bianchi V., Biancuzzi H., Radulescu R. B., Bignell M. B., Biloslavo A., Bini R., Bissacco D., Boati P., Boddaert G., Bogdanic B., Bombardini C., Bonavina L., Bonomo L., Bottari A., Bouliaris K., Brachini G., Brillantino A., Brisinda G., Bulanauca M. M., Buonomo L. A., Burcharth J., Buscemi S., Calabretto F., Calini G., Calu V., Campanile F. C., Campo Dall'Orto R., Campos-Serra A., Carvas J. M., Cascella M., Pattacini G. C., Celentano V., Centonze D. C., Ceresoli M., Chatzipetris D., Chessa A., Chiarello M. M., Chirica M., Chooklin S., Chouliaras C., Chowdhury S., Cianci P., Cillara N., Cimbanassi S., Cioffi S. P. B., Colais-Ruiz E., Colak E., Conti L., Coppola A., de Sa T. C., Costa S. D., Cozza V., Curro' G., Dabekaussen K. F. A. -S. A., D'acapito F., Damaskos D., D'Ambrosio G., Das K., Davies R. J., de Beaux A. C., De Lebrusant Fernandez S. P., De Luca A., De Simone B., De Stefano F., Degrate L., Demetrashvili Z., Demetriades A. K., Detanac D. S., Dezi A., Di Buono G., Carlo I. -D. I., Di Lascio P., Di Martino M., Di Saverio S., Diaconescu B., Diaz J. J., Dibra R., Dimitrov E. N., Dinuzzi V. P., Dios-Barbeito S., Diyani J. F. A., Dogjani A., Domanin M., D'Oria M., Munoz-Cruzado V. D., East B., Ekelund M., Ekwen G. T., Elbaih A. H., Elhadi M., Enninghorst N., Ernisova M., Escalera-Antezana J. P., Esposito S., Esposito G., Estaire-Gamez M., Fara C. N., Farre R., Favi F., Ferrario L., Ferrario di Tor Vajana A., Filisetti C., Fleres F., Fonseca V. C., Forero-Torres A., Forfori F., Fortuna L., Fradelos E., Fraga G. P., Fransvea P., Frassini S., Frazzetta G., Frigerio I., Frountzas M., Gachabayov M., Galeiras R., Garcaa B. M., Garcia Vazquez A., Gargarella S., Garzali I. U., Ghannam W. M., Ghazi F. N., Gillman L. M., Gioco R., Giordano A., Giordano L., Giove C., Giraudo G., Giuffrida M., Capponi M. G., Gois E., Gomes C. A., Gomes F. C., Gonsaga R. A. T., Gonullu E., Goosen J., Goranovic T., Gracia-Roman R., Graziano G. M. P., Griffiths E. A., Guagni T., Hadzhiev D. B., Haidar M. G., Hamid H. K. S., Hardcastle T. C., Hayati F., Healey A. J., Hecker A., Hecker M., Garcia E. F. H., hodonou A. M., huaman E., Huerta M., Ibrahim A. F., Ibrahim B. M. S., Ietto G., Inama M., Ioannidis O., Isik A., Ismail N., Ismail A. M. H., Jailani R. F., Jang J. Y., Kalfountzos C., Kalipershad S. N. R., Kaouras E., Kaplan L. J., Kara Y., Karamagioli E., Karamarkovia A., Katsaros I., Kavalakat A. J., Kechagias A., Kenig J., Kessel B. J., Khan J. S., Khokha V., Kim J. I., Kirkpatrick A. W., Klappenbach R., Kobe Y., Lymperis E. K., Kok K. Y. Y., Kong V., Korkolis D. P., Koukoulis G., Kovacevic B., Kruger V. F., Kryvoruchko I. A., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Lapolla P., Licari L., Lisi G., Litvin A., Lizarazu A., Bayo H. L., Lohsiriwat V., Moreira C. C. L., Lostoridis E., Luna A. T., Luppi D., V G. M. M., Maegele M., Maggiore D., Magnone S., Maier R. V., Major P., Manangi M., manetti A., Mantoglu B., Marafante C., Mariani F., Marinis A., Mariot E. A. S., Marseglia G. R., Martanez-Parez A., Martines G., Perez A. M., Martino C., Mascagni P., Massalou D., Mataas-Garcaa B., Mazzarella G., Mazzarolo G., Melo R. B., Mendoza-Moreno F., Meric S., Meyer J., Miceli L., Michalopoulos N. V., Milana F., Mingoli A., Mishra T. S., Mohamed M., Mohamed M. I. E. A., Mohamedahmed A. Y., Mohammed M. J. S., Mohan R., Moore E. E., Morales-Garcia D., Muhrbeck M., Mulita F., Mustafa S. M. S., Muttillo E. M., Naimzada M. D., Navsaria P. H., Negoi I., Nespoli L., Nguyen C., Nidaw M. K., Nigri G., Nikolopoulos I., O'Connor D. B., Ogundipe H. D., Oliveri C., Olmi S., Ong E. C. W., Orecchia L., Osipov A. V., Othman M. F., Pace M., Pacilli M., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papa M. V., Papaconstantinou D., Papadoliopoulou M., Papadopoulos A., Papis D., Pararas N., Parreira J. G., Parry N. G., Pata F., Patel T., Paterson-Brown S., Pavone G., Pecchini F., Pellino G., Pelloni M., Peloso A., del Pozo E. P., Pereira R. G., Pereira B. M., perez A. L., Perra T., Perrone G., Pesce A., Petagna L., Petracca G., Phupong V., Picardi B., Picciariello A., Piccoli M., Piccolo D., Picetti E., Pikoulis Pikoulis E., Pintar T., Pirozzolo G., Piscioneri F., Podda M., Porcu A., Privitera F., Punzo C., Quaresima S., Quiodettis M. A., Qvist N., Rahim R., de Almeida F. R., Ramely R. B., Rasa H. K., Reichert M., Reinisch-Liese A., Renne A., Riccetti C., Rodriguez-Luna M. R., Roizblatt D., Romanzi A., Romeo L., Roscio F. P. M., Rosnelifaizur R. B., Rossi S., Rubiano A. M., Ruiz-Ascar E., Sakakushev B. E., Salamea J. C., Sall I., Samarakoon L. B., Sammartano F., Arteaga A. S., Sanchez-Cordero S., Santoanastaso D. P. M., Sasia D., Sato N., Savchuk A., Sawyer R. G., Scaioli G., Schizas D., Sebastiani S., Seeliger B., Lohse H. A. S., Seretis C., Sermonesi G., Serradilla-Martin M., Shelat V. G., Shlyapnikov S., Sidiropoulos T., Simoes R. L., Siragusa L., Siribumrungwong B., Slavchev M., Solaini L., soldini G., Sopuev A., Soreide K., Sovatzidis A., Stahel P. F., Strickland M., Sultan M. A. H., Sydorchuk R., Sydorchuk L., Syed S. M. A. M., Syed A. M., Tallon-Aguilar L., Tamburini A. M., Tamini N., Tan E. C. T. H., Tan J. H., Tarasconi A., Tartaglia N., Tartaglia G., Tartaglia D., Taylor J. V., Tebala G. D., Teuben M., Theodorou A., Tolonen M., Tomasicchio G., Toro A., Torre B., Triantafyllou T., Trigiante Trigiante G., Tripepi M., Trostchansky J., Tsekouras K., Turrado-Rodriguez V., Tutino R., Uccelli M., Uchikov P. A., Ugarte-Sierra B., Ukkonen M. T., Vailas M., Vassiliu P. G., Vazquez A. G., Vazquez R. G., Verde J. E., Verde J. M., Veroux M., Vigano J., Vilallonga R., Visconti D., Vittori A., Waledziak M., Wannatoop T., Widmer L. W., Wilson M. S. J., Wong T. H., Xenaki S., Yu B., Yule S., Zachariah S. K., Zacharis G., Zaghi C., Zakaria A. D., Zambrano D. A., Zampitis N., Zampogna B., Zangha S., Zapsalis K., Zattoni F., Zese M., Farre S. P., Pegoraro V., Zantedeschi M., Reitano E., Pizzocaro E., Cobianchi, L, Dal Mas, F, Agnoletti, V, Ansaloni, L, Biffl, W, Butturini, G, Campostrini, S, Catena, F, Denicolai, S, Fugazzola, P, Martellucci, J, Massaro, M, Previtali, P, Ruta, F, Venturi, A, Woltz, S, Kaafarani, H, Loftus, T, Aapoaylu, R, Abbott, K, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Adamovich, D, Agresta, F, Agrusa, A, Akin, E, Alessiani, M, Alexandrino, H, Bidoli, C, Ali, S, Mihai, V, Almeida, P, Al-Shehari, M, Altomare, M, Amico, F, Ammendola, M, Andreuccetti, J, Anestiadou, E, Annicchiarico, A, Antonelli, A, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Arvieux, C, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bacchiocchi, G, Bagnoli, C, Bahouth, H, Baili, E, Bains, L, Baiocchi, G, Bala, M, Balaguacopyright, C, Balalis, D, Baldini, E, Baraket, O, Baral, S, Barone, M, Gonzalez Barranquero, A, Barreras, J, Bass, G, Bayhan, Z, Bellanova, G, Ben-Ishay, O, Bert, F, Bianchi, V, Biancuzzi, H, Radulescu, R, Bignell, M, Biloslavo, A, Bini, R, Bissacco, D, Boati, P, Boddaert, G, Bogdanic, B, Bombardini, C, Bonavina, L, Bonomo, L, Bottari, A, Bouliaris, K, Brachini, G, Brillantino, A, Brisinda, G, Bulanauca, M, Buonomo, L, Burcharth, J, Buscemi, S, Calabretto, F, Calini, G, Calu, V, Campanile, F, Campo Dall'Orto, R, Campos-Serra, A, Carvas, J, Cascella, M, Pattacini, G, Celentano, V, Centonze, D, Ceresoli, M, Chatzipetris, D, Chessa, A, Chiarello, M, Chirica, M, Chooklin, S, Chouliaras, C, Chowdhury, S, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colais-Ruiz, E, Colak, E, Conti, L, Coppola, A, de Sa, T, Costa, S, Cozza, V, Curro', G, Dabekaussen, K, D'Acapito, F, Damaskos, D, D'Ambrosio, G, Das, K, Davies, R, de Beaux, A, De Lebrusant Fernandez, S, De Luca, A, De Simone, B, De Stefano, F, Degrate, L, Demetrashvili, Z, Demetriades, A, Detanac, D, Dezi, A, Di Buono, G, Carlo, I, Di Lascio, P, Di Martino, M, Di Saverio, S, Diaconescu, B, Diaz, J, Dibra, R, Dimitrov, E, Dinuzzi, V, Dios-Barbeito, S, Diyani, J, Dogjani, A, Domanin, M, D'Oria, M, Munoz-Cruzado, V, East, B, Ekelund, M, Ekwen, G, Elbaih, A, Elhadi, M, Enninghorst, N, Ernisova, M, Escalera-Antezana, J, Esposito, S, Esposito, G, Estaire-Gamez, M, Fara, C, Farre, R, Favi, F, Ferrario, L, Ferrario di Tor Vajana, A, Filisetti, C, Fleres, F, Fonseca, V, Forero-Torres, A, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Frassini, S, Frazzetta, G, Frigerio, I, Frountzas, M, Gachabayov, M, Galeiras, R, Garcaa, B, Garcia Vazquez, A, Gargarella, S, Garzali, I, Ghannam, W, Ghazi, F, Gillman, L, Gioco, R, Giordano, A, Giordano, L, Giove, C, Giraudo, G, Giuffrida, M, Capponi, M, Gois, E, Gomes, C, Gomes, F, Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Gracia-Roman, R, Graziano, G, Griffiths, E, Guagni, T, Hadzhiev, D, Haidar, M, Hamid, H, Hardcastle, T, Hayati, F, Healey, A, Hecker, A, Hecker, M, Garcia, E, Hodonou, A, Huaman, E, Huerta, M, Ibrahim, A, Ibrahim, B, Ietto, G, Inama, M, Ioannidis, O, Isik, A, Ismail, N, Ismail, A, Jailani, R, Jang, J, Kalfountzos, C, Kalipershad, S, Kaouras, E, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Katsaros, I, Kavalakat, A, Kechagias, A, Kenig, J, Kessel, B, Khan, J, Khokha, V, Kim, J, Kirkpatrick, A, Klappenbach, R, Kobe, Y, Lymperis, E, Kok, K, Kong, V, Korkolis, D, Koukoulis, G, Kovacevic, B, Kruger, V, Kryvoruchko, I, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Lapolla, P, Licari, L, Lisi, G, Litvin, A, Lizarazu, A, Bayo, H, Lohsiriwat, V, Moreira, C, Lostoridis, E, Luna, A, Luppi, D, V, G, Maegele, M, Maggiore, D, Magnone, S, Maier, R, Major, P, Manangi, M, Manetti, A, Mantoglu, B, Marafante, C, Mariani, F, Marinis, A, Mariot, E, Marseglia, G, Martanez-Parez, A, Martines, G, Perez, A, Martino, C, Mascagni, P, Massalou, D, Mataas-Garcaa, B, Mazzarella, G, Mazzarolo, G, Melo, R, Mendoza-Moreno, F, Meric, S, Meyer, J, Miceli, L, Michalopoulos, N, Milana, F, Mingoli, A, Mishra, T, Mohamed, M, Mohamedahmed, A, Mohammed, M, Mohan, R, Moore, E, Morales-Garcia, D, Muhrbeck, M, Mulita, F, Mustafa, S, Muttillo, E, Naimzada, M, Navsaria, P, Negoi, I, Nespoli, L, Nguyen, C, Nidaw, M, Nigri, G, Nikolopoulos, I, O'Connor, D, Ogundipe, H, Oliveri, C, Olmi, S, Ong, E, Orecchia, L, Osipov, A, Othman, M, Pace, M, Pacilli, M, Pagani, L, Palomba, G, Pantalone, D, Panyko, A, Paolillo, C, Papa, M, Papaconstantinou, D, Papadoliopoulou, M, Papadopoulos, A, Papis, D, Pararas, N, Parreira, J, Parry, N, Pata, F, Patel, T, Paterson-Brown, S, Pavone, G, Pecchini, F, Pellino, G, Pelloni, M, Peloso, A, del Pozo, E, Pereira, R, Pereira, B, Perra, T, Perrone, G, Pesce, A, Petagna, L, Petracca, G, Phupong, V, Picardi, B, Picciariello, A, Piccoli, M, Piccolo, D, Picetti, E, Pikoulis Pikoulis, E, Pintar, T, Pirozzolo, G, Piscioneri, F, Podda, M, Porcu, A, Privitera, F, Punzo, C, Quaresima, S, Quiodettis, M, Qvist, N, Rahim, R, de Almeida, F, Ramely, R, Rasa, H, Reichert, M, Reinisch-Liese, A, Renne, A, Riccetti, C, Rodriguez-Luna, M, Roizblatt, D, Romanzi, A, Romeo, L, Roscio, F, Rosnelifaizur, R, Rossi, S, Rubiano, A, Ruiz-Ascar, E, Sakakushev, B, Salamea, J, Sall, I, Samarakoon, L, Sammartano, F, Arteaga, A, Sanchez-Cordero, S, Santoanastaso, D, Sasia, D, Sato, N, Savchuk, A, Sawyer, R, Scaioli, G, Schizas, D, Sebastiani, S, Seeliger, B, Lohse, H, Seretis, C, Sermonesi, G, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Sidiropoulos, T, Simoes, R, Siragusa, L, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Sopuev, A, Soreide, K, Sovatzidis, A, Stahel, P, Strickland, M, Sultan, M, Sydorchuk, R, Sydorchuk, L, Syed, S, Syed, A, Tallon-Aguilar, L, Tamburini, A, Tamini, N, Tan, E, Tan, J, Tarasconi, A, Tartaglia, N, Tartaglia, G, Tartaglia, D, Taylor, J, Tebala, G, Teuben, M, Theodorou, A, Tolonen, M, Tomasicchio, G, Toro, A, Torre, B, Triantafyllou, T, Trigiante Trigiante, G, Tripepi, M, Trostchansky, J, Tsekouras, K, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Uchikov, P, Ugarte-Sierra, B, Ukkonen, M, Vailas, M, Vassiliu, P, Vazquez, A, Vazquez, R, Verde, J, Veroux, M, Vigano, J, Vilallonga, R, Visconti, D, Vittori, A, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Wong, T, Xenaki, S, Yu, B, Yule, S, Zachariah, S, Zacharis, G, Zaghi, C, Zakaria, A, Zambrano, D, Zampitis, N, Zampogna, B, Zangha, S, Zapsalis, K, Zattoni, F, Zese, M, Farre, S, Pegoraro, V, Zantedeschi, M, Reitano, E, Pizzocaro, E, Cobianchi L., Dal Mas F., Agnoletti V., Ansaloni L., Biffl W., Butturini G., Campostrini S., Catena F., Denicolai S., Fugazzola P., Martellucci J., Massaro M., Previtali P., Ruta F., Venturi A., Woltz S., Kaafarani H. M., Loftus T. J., Aapoaylu R., Abbott K. L., Abdelmalik A., Abebe N. S., Abu-Zidan F., Adam Y. A. Y., Adamou H., Adamovich D. M., Agresta F., Agrusa A., Akin E., Alessiani M., Alexandrino H., Bidoli C., Ali S. M., Mihai V. A., Almeida P. M., Al-Shehari M. M., Altomare M., Amico F., Ammendola M., Andreuccetti J., Anestiadou E., Annicchiarico A., Antonelli A., Aparicio-Sanchez D., Ardito A., Argenio G., Arvieux C. C., Arvieux C., Askevold I. H., Atanasov B. T., Augustin G., Awad S. S., Bacchiocchi G., Bagnoli C., Bahouth H., Baili E., Bains L., Baiocchi G. L., Bala M., BalaguaCopyright C., Balalis D., Baldini E., Baraket O., Baral S., Barone M., Gonzalez Barranquero A., Barreras J. A., Bass G. A., Bayhan Z., Bellanova G., Ben-Ishay O., Bert F., Bianchi V., Biancuzzi H., Radulescu R. B., Bignell M. B., Biloslavo A., Bini R., Bissacco D., Boati P., Boddaert G., Bogdanic B., Bombardini C., Bonavina L., Bonomo L., Bottari A., Bouliaris K., Brachini G., Brillantino A., Brisinda G., Bulanauca M. M., Buonomo L. A., Burcharth J., Buscemi S., Calabretto F., Calini G., Calu V., Campanile F. C., Campo Dall'Orto R., Campos-Serra A., Carvas J. M., Cascella M., Pattacini G. C., Celentano V., Centonze D. C., Ceresoli M., Chatzipetris D., Chessa A., Chiarello M. M., Chirica M., Chooklin S., Chouliaras C., Chowdhury S., Cianci P., Cillara N., Cimbanassi S., Cioffi S. P. B., Colais-Ruiz E., Colak E., Conti L., Coppola A., de Sa T. C., Costa S. D., Cozza V., Curro' G., Dabekaussen K. F. A. -S. A., D'acapito F., Damaskos D., D'Ambrosio G., Das K., Davies R. J., de Beaux A. C., De Lebrusant Fernandez S. P., De Luca A., De Simone B., De Stefano F., Degrate L., Demetrashvili Z., Demetriades A. K., Detanac D. S., Dezi A., Di Buono G., Carlo I. -D. I., Di Lascio P., Di Martino M., Di Saverio S., Diaconescu B., Diaz J. J., Dibra R., Dimitrov E. N., Dinuzzi V. P., Dios-Barbeito S., Diyani J. F. A., Dogjani A., Domanin M., D'Oria M., Munoz-Cruzado V. D., East B., Ekelund M., Ekwen G. T., Elbaih A. H., Elhadi M., Enninghorst N., Ernisova M., Escalera-Antezana J. P., Esposito S., Esposito G., Estaire-Gamez M., Fara C. N., Farre R., Favi F., Ferrario L., Ferrario di Tor Vajana A., Filisetti C., Fleres F., Fonseca V. C., Forero-Torres A., Forfori F., Fortuna L., Fradelos E., Fraga G. P., Fransvea P., Frassini S., Frazzetta G., Frigerio I., Frountzas M., Gachabayov M., Galeiras R., Garcaa B. M., Garcia Vazquez A., Gargarella S., Garzali I. U., Ghannam W. M., Ghazi F. N., Gillman L. M., Gioco R., Giordano A., Giordano L., Giove C., Giraudo G., Giuffrida M., Capponi M. G., Gois E., Gomes C. A., Gomes F. C., Gonsaga R. A. T., Gonullu E., Goosen J., Goranovic T., Gracia-Roman R., Graziano G. M. P., Griffiths E. A., Guagni T., Hadzhiev D. B., Haidar M. G., Hamid H. K. S., Hardcastle T. C., Hayati F., Healey A. J., Hecker A., Hecker M., Garcia E. F. H., hodonou A. M., huaman E., Huerta M., Ibrahim A. F., Ibrahim B. M. S., Ietto G., Inama M., Ioannidis O., Isik A., Ismail N., Ismail A. M. H., Jailani R. F., Jang J. Y., Kalfountzos C., Kalipershad S. N. R., Kaouras E., Kaplan L. J., Kara Y., Karamagioli E., Karamarkovia A., Katsaros I., Kavalakat A. J., Kechagias A., Kenig J., Kessel B. J., Khan J. S., Khokha V., Kim J. I., Kirkpatrick A. W., Klappenbach R., Kobe Y., Lymperis E. K., Kok K. Y. Y., Kong V., Korkolis D. P., Koukoulis G., Kovacevic B., Kruger V. F., Kryvoruchko I. A., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Lapolla P., Licari L., Lisi G., Litvin A., Lizarazu A., Bayo H. L., Lohsiriwat V., Moreira C. C. L., Lostoridis E., Luna A. T., Luppi D., V G. M. M., Maegele M., Maggiore D., Magnone S., Maier R. V., Major P., Manangi M., manetti A., Mantoglu B., Marafante C., Mariani F., Marinis A., Mariot E. A. S., Marseglia G. R., Martanez-Parez A., Martines G., Perez A. M., Martino C., Mascagni P., Massalou D., Mataas-Garcaa B., Mazzarella G., Mazzarolo G., Melo R. B., Mendoza-Moreno F., Meric S., Meyer J., Miceli L., Michalopoulos N. V., Milana F., Mingoli A., Mishra T. S., Mohamed M., Mohamed M. I. E. A., Mohamedahmed A. Y., Mohammed M. J. S., Mohan R., Moore E. E., Morales-Garcia D., Muhrbeck M., Mulita F., Mustafa S. M. S., Muttillo E. M., Naimzada M. D., Navsaria P. H., Negoi I., Nespoli L., Nguyen C., Nidaw M. K., Nigri G., Nikolopoulos I., O'Connor D. B., Ogundipe H. D., Oliveri C., Olmi S., Ong E. C. W., Orecchia L., Osipov A. V., Othman M. F., Pace M., Pacilli M., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papa M. V., Papaconstantinou D., Papadoliopoulou M., Papadopoulos A., Papis D., Pararas N., Parreira J. G., Parry N. G., Pata F., Patel T., Paterson-Brown S., Pavone G., Pecchini F., Pellino G., Pelloni M., Peloso A., del Pozo E. P., Pereira R. G., Pereira B. M., perez A. L., Perra T., Perrone G., Pesce A., Petagna L., Petracca G., Phupong V., Picardi B., Picciariello A., Piccoli M., Piccolo D., Picetti E., Pikoulis Pikoulis E., Pintar T., Pirozzolo G., Piscioneri F., Podda M., Porcu A., Privitera F., Punzo C., Quaresima S., Quiodettis M. A., Qvist N., Rahim R., de Almeida F. R., Ramely R. B., Rasa H. K., Reichert M., Reinisch-Liese A., Renne A., Riccetti C., Rodriguez-Luna M. R., Roizblatt D., Romanzi A., Romeo L., Roscio F. P. M., Rosnelifaizur R. B., Rossi S., Rubiano A. M., Ruiz-Ascar E., Sakakushev B. E., Salamea J. C., Sall I., Samarakoon L. B., Sammartano F., Arteaga A. S., Sanchez-Cordero S., Santoanastaso D. P. M., Sasia D., Sato N., Savchuk A., Sawyer R. G., Scaioli G., Schizas D., Sebastiani S., Seeliger B., Lohse H. A. S., Seretis C., Sermonesi G., Serradilla-Martin M., Shelat V. G., Shlyapnikov S., Sidiropoulos T., Simoes R. L., Siragusa L., Siribumrungwong B., Slavchev M., Solaini L., soldini G., Sopuev A., Soreide K., Sovatzidis A., Stahel P. F., Strickland M., Sultan M. A. H., Sydorchuk R., Sydorchuk L., Syed S. M. A. M., Syed A. M., Tallon-Aguilar L., Tamburini A. M., Tamini N., Tan E. C. T. H., Tan J. H., Tarasconi A., Tartaglia N., Tartaglia G., Tartaglia D., Taylor J. V., Tebala G. D., Teuben M., Theodorou A., Tolonen M., Tomasicchio G., Toro A., Torre B., Triantafyllou T., Trigiante Trigiante G., Tripepi M., Trostchansky J., Tsekouras K., Turrado-Rodriguez V., Tutino R., Uccelli M., Uchikov P. A., Ugarte-Sierra B., Ukkonen M. T., Vailas M., Vassiliu P. G., Vazquez A. G., Vazquez R. G., Verde J. E., Verde J. M., Veroux M., Vigano J., Vilallonga R., Visconti D., Vittori A., Waledziak M., Wannatoop T., Widmer L. W., Wilson M. S. J., Wong T. H., Xenaki S., Yu B., Yule S., Zachariah S. K., Zacharis G., Zaghi C., Zakaria A. D., Zambrano D. A., Zampitis N., Zampogna B., Zangha S., Zapsalis K., Zattoni F., Zese M., Farre S. P., Pegoraro V., Zantedeschi M., Reitano E., and Pizzocaro E.
- Abstract
Background: Shared decision-making (SDM) between clinicians and patients is one of the pillars of the modern patient-centric philosophy of care. This study aims to explore SDM in the discipline of trauma and emergency surgery, investigating its interpretation as well as the barriers and facilitators for its implementation among surgeons. Methods: Grounding on the literature on the topics of the understanding, barriers, and facilitators of SDM in trauma and emergency surgery, a survey was created by a multidisciplinary committee and endorsed by the World Society of Emergency Surgery (WSES). The survey was sent to all 917 WSES members, advertised through the society’s website, and shared on the society’s Twitter profile. Results: A total of 650 trauma and emergency surgeons from 71 countries in five continents participated in the initiative. Less than half of the surgeons understood SDM, and 30% still saw the value in exclusively engaging multidisciplinary provider teams without involving the patient. Several barriers to effectively partnering with the patient in the decision-making process were identified, such as the lack of time and the need to concentrate on making medical teams work smoothly. Discussion: Our investigation underlines how only a minority of trauma and emergency surgeons understand SDM, and perhaps, the value of SDM is not fully accepted in trauma and emergency situations. The inclusion of SDM practices in clinical guidelines may represent the most feasible and advocated solutions.
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- 2023
17. Acute diverticulitis in immunocompromised patients: evidence from an international multicenter observational registry (Web-based International Register of Emergency Surgery and Trauma, Wires-T)
- Author
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Tartaglia, D., Cremonini, C., Annunziata, E., Catena, F., Sartelli, M., Kirkpatrick, A. W., Musetti, S., Strambi, S., Chiarugi, M., Coccolini, F., Salvetti, F., Fugazzola, P., Ceresoli, M., Benedetti, F., Elisa, N. G., Litvin, A., Lostoridis, E., Ahmed, A. Y. Y. M., Manatakis, D., Negoi, I., Ioannidis, O., Uzunoglu, M. Y., Tochie, J. N., Cillara, N., Tomadze, G., Bala, M., Isik, A., Fonseca, V. C., Bellanova, G., Ghannam, W., Yalkin, O., Garcia, F. H., Altintoprak, F., Hadzhiev, D., Chirica, M., Zese, M., Balalis, D., Cui, Y., Luppi, D., Romeo, L., Muratore, A., Lunghi, E. G., Yovtchev, Y., Dimitrov, E., Nikolopoulos, I., Omerovic, M., Zizzo, M., Ugoletti, L., Costa, G., Scalzone, R., Perrone, S., Occhionorelli, S., Nardi, M., Gubbiotti, F., Muhtaroglu, A., Scaramuzzo, R., Corte, H., Yanez, C., Zakaria, A. D., Seretis, C., Gelmini, R., Pappalardo, V., Paratore, F., Sydorchuk, R., Mulita, F., Kara, Y., Toma, E. A., Vailas, M., Sotiropoulou, M., Elbahnasawy, M., Sibilla, M. G., Martines, G., Goksoy, B., Parini, D., Zaghi, C., Podda, M., Osipov, A., Brisinda, G., Gambino, G., Doklestic, L. A. K., Loncar, Z., Micic, D., Lesevic, I., D'Agostino, F., Garzali, I. U., Caicedo, Y., Marcela, L., Marin, P. A. G., Perivoliotis, K., Ntentas, I., Kuptsov, A., Chowdhury, S., Patel, T., Tartaglia, D, Cremonini, C, Annunziata, E, Catena, F, Sartelli, M, Kirkpatrick, A, Musetti, S, Strambi, S, Chiarugi, M, Coccolini, F, Salvetti, F, Fugazzola, P, Ceresoli, M, Benedetti, F, Elisa, N, Litvin, A, Lostoridis, E, Ahmed, A, Manatakis, D, Negoi, I, Ioannidis, O, Uzunoglu, M, Tochie, J, Cillara, N, Tomadze, G, Bala, M, Isik, A, Fonseca, V, Bellanova, G, Ghannam, W, Yalkin, O, Garcia, F, Altintoprak, F, Hadzhiev, D, Chirica, M, Zese, M, Balalis, D, Cui, Y, Luppi, D, Romeo, L, Muratore, A, Lunghi, E, Yovtchev, Y, Dimitrov, E, Nikolopoulos, I, Omerovic, M, Zizzo, M, Ugoletti, L, Costa, G, Scalzone, R, Perrone, S, Occhionorelli, S, Nardi, M, Gubbiotti, F, Muhtaroglu, A, Scaramuzzo, R, Corte, H, Yanez, C, Zakaria, A, Seretis, C, Gelmini, R, Pappalardo, V, Paratore, F, Sydorchuk, R, Mulita, F, Kara, Y, Toma, E, Vailas, M, Sotiropoulou, M, Elbahnasawy, M, Sibilla, M, Martines, G, Goksoy, B, Parini, D, Zaghi, C, Podda, M, Osipov, A, Brisinda, G, Gambino, G, Doklestic, L, Loncar, Z, Micic, D, Lesevic, I, D'Agostino, F, Garzali, I, Caicedo, Y, Marcela, L, Marin, P, Perivoliotis, K, Ntentas, I, Kuptsov, A, Chowdhury, S, and Patel, T
- Subjects
Medical therapy ,Acute diverticuliti ,Gastroenterology ,Acute diverticulitis ,Surgery ,Immunocompromised - Abstract
Background Immunocompromised patients with acute diverticulitis are at increased risk of morbidity and mortality. The aim of this study was to compare clinical presentations, types of treatment, and outcomes between immunocompromised and immunocompetent patients with acute diverticulitis. Methods We compared the data of patients with acute diverticulitis extracted from the Web-based International Registry of Emergency Surgery and Trauma (WIRES-T) from January 2018 to December 2021. First, two groups were identified: medical therapy (A) and surgical therapy (B). Each group was divided into three subgroups: nonimmunocompromised (grade 0), mildly to moderately (grade 1), and severely immunocompromised (grade 2). Results Data from 482 patients were analyzed—229 patients (47.5%) [M:F = 1:1; median age: 60 (24–95) years] in group A and 253 patients (52.5%) [M:F = 1:1; median age: 71 (26–94) years] in group B. There was a significant difference between the two groups in grade distribution: 69.9% versus 38.3% for grade 0, 26.6% versus 51% for grade 1, and 3.5% versus 10.7% for grade 2 (p p = 0.027) was more common in higher grades of immunodeficiency. Patients with grade 2 needed longer hospitalization (p = 0.005). In group B, a similar condition was found in terms of severe sepsis (p = 0.002), quick Sequential Organ Failure Assessment score > 2 (p = 0.0002), and Mannheim Peritonitis Index (p = 0.010). A Hartmann’s procedure is mainly performed in grades 1–2 (p p = 0.047). Mortality was higher in the immunocompromised patients (p = 0.002). Conclusions Immunocompromised patients with acute diverticulitis present with a more severe clinical picture. When surgery is required, immunocompromised patients mainly undergo a Hartmann’s procedure. Postoperative morbidity and mortality are, however, higher in immunocompromised patients, who also require a longer hospital stay.
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- 2023
18. Colorectal neoplastic emergencies in immunocompromised patients: preliminary result from the Web-based International Register of Emergency Surgery and Trauma (WIRES-T trial)
- Author
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Coccolini F., Mazzoni A., Cremonini C., Cobuccio L., Pucciarelli M., Vetere G., Borelli B., Strambi S., Musetti S., Miccoli M., Cremolini C., Salvetti F., Fugazzola P., Ceresoli M., Elisa N. G., Litvin A., Lostoridis E., Ahmed A. Y. Y. M., Manatakis D., Negoi I., Ioannidis O., Uzunoglu M. Y., Tochie J. N., Cillara N., Tomadze G., Bala M., Isik A., Fonseca V. C., Bellanova G., Ghannam W., Yalkin O., Garcia F. H., Altintoprak F., Hadzhiev D., Chirica M., Zese M., Balalis D., Cui Y., Luppi D., Romeo L., Muratore A., Lunghi E. G., Yovtchev Y., Nikolopoulos I., Omerovic M., Zizzo M., Ugoletti L., Costa G., Scalzone R., Perrone S., Occhionorelli S., Nardi M., Gubbiotti F., Catena F., Muhtaroglu A., Scaramuzzo R., Corte H., Yanez C., Zakaria A. D., Seretis C., Gelmini R., Pappalardo V., Paratore F., Sydorchuk R., Mulita F., Kara Y., Toma E. A., Vailas M., Sotiropoulou M., Benedetti F., Elbahnasawy M., Sibilla M. G., Martines G., Goksoy B., Parini D., Zaghi C., Podda M., Osipov A., Brisinda G., Gambino G., Akhmeteli L., Doklestic K., Loncar Z., Micic D., Lesevic I., D'Agostino F., Garzali I. U., Caicedo Y., Marcela L., Marin P. A. G., Perivoliotis K., Ntentas I., Kuptsov A., Dimitrov E., Chowdhury S., Patel T., Sartelli M., Tartaglia D., Chiarugi M., Coccolini, F, Mazzoni, A, Cremonini, C, Cobuccio, L, Pucciarelli, M, Vetere, G, Borelli, B, Strambi, S, Musetti, S, Miccoli, M, Cremolini, C, Salvetti, F, Fugazzola, P, Ceresoli, M, Elisa, N, Litvin, A, Lostoridis, E, Ahmed, A, Manatakis, D, Negoi, I, Ioannidis, O, Uzunoglu, M, Tochie, J, Cillara, N, Tomadze, G, Bala, M, Isik, A, Fonseca, V, Bellanova, G, Ghannam, W, Yalkin, O, Garcia, F, Altintoprak, F, Hadzhiev, D, Chirica, M, Zese, M, Balalis, D, Cui, Y, Luppi, D, Romeo, L, Muratore, A, Lunghi, E, Yovtchev, Y, Nikolopoulos, I, Omerovic, M, Zizzo, M, Ugoletti, L, Costa, G, Scalzone, R, Perrone, S, Occhionorelli, S, Nardi, M, Gubbiotti, F, Catena, F, Muhtaroglu, A, Scaramuzzo, R, Corte, H, Yanez, C, Zakaria, A, Seretis, C, Gelmini, R, Pappalardo, V, Paratore, F, Sydorchuk, R, Mulita, F, Kara, Y, Toma, E, Vailas, M, Sotiropoulou, M, Benedetti, F, Elbahnasawy, M, Sibilla, M, Martines, G, Goksoy, B, Parini, D, Zaghi, C, Podda, M, Osipov, A, Brisinda, G, Gambino, G, Akhmeteli, L, Doklestic, K, Loncar, Z, Micic, D, Lesevic, I, D'Agostino, F, Garzali, I, Caicedo, Y, Marcela, L, Marin, P, Perivoliotis, K, Ntentas, I, Kuptsov, A, Dimitrov, E, Chowdhury, S, Patel, T, Sartelli, M, Tartaglia, D, and Chiarugi, M
- Subjects
Survival ,Colon ,Emergency ,Acute care ,Surgery ,Morbidity ,Mortality ,Immunosuppression ,Cancer - Abstract
Association of advanced age, neoplastic disease and immunocompromission (IC) may lead to surgical emergencies. Few data exist about this topic. Present study reports the preliminary data from the WIRES-T trial about patients managed for colorectal neoplastic emergencies in immunocompromised patients. The required data were taken from a prospective observational international register. The study was approved by the Ethical Committee with approval n. 17575; ClinicalTrials.gov Identifier: NCT03643718. 839 patients were collected; 753 (80.7%) with mild–moderate IC and 86 (10.3%) with severe. Median age was 71.9 years and 73 years, respectively, in the two groups. The causes of mild–moderate IC were reported such malignancy (753–100%), diabetes (103–13.7%), malnutrition (26–3.5%) and uremia (1–0.1%), while severe IC causes were steroids treatment (14–16.3%); neutropenia (7–8.1%), malignancy on chemotherapy (71–82.6%). Preoperative risk classification were reported as follow: mild–moderate: ASA 1–14 (1.9%); ASA 2–202 (26.8%); ASA 3–341 (45.3%); ASA 4–84 (11.2%); ASA 5–7 (0.9%); severe group: ASA 1-1 patient (1.2%); ASA 2–16 patients (18.6%); ASA 3–41 patients (47.7%); ASA 4–19 patients (22.1%); ASA 5–3 patients (3.5%); lastly, ASA score was unavailable for 105 cases (13.9%) in mild–moderate group and in 6 cases (6.9%) in severe group. All the patients enrolled underwent urgent/emergency surgery Damage control approach with open abdomen was adopted in 18 patients. Mortality was 5.1% and 12.8%, respectively, in mild–moderate and severe groups. Long-term survival data: in mild–moderate disease-free survival (median, IQR) is 28 (10–91) and in severe IC, it is 21 (10–94). Overall survival (median, IQR) is 44 (18–99) and 26 (20–90) in mild–moderate and severe, respectively; the same is for post-progression survival (median, IQR) 29 (16–81) and 28, respectively. Univariate and multivariate analyses showed as the only factor influencing mortality in mild–moderate and severe IC is the ASA score. Colorectal neoplastic emergencies in immunocompromised patients are more frequent in elderly. Sigmoid and right colon are the most involved. Emergency surgery is at higher risk of complication and mortality; however, management in dedicated emergency surgery units is necessary to reduce disease burden and to optimize results by combining oncological and acute care principles. This approach may improve outcomes to obtain clinical advantages for patients like those observed in elective scenario. Lastly, damage control approach seems feasible and safe in selected patients.
- Published
- 2023
19. Diversity and ethics in trauma and acute care surgery teams: results from an international survey
- Author
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Cobianchi, L, Dal Mas, F, Massaro, M, Biffl, W, Catena, F, Coccolini, F, Dionigi, B, Dionigi, P, Di Saverio, S, Fugazzola, P, Kluger, Y, Leppaniemi, A, Moore, E, Sartelli, M, Velmahos, G, Woltz, S, Angelos, P, Ansaloni, L, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Agrusa, A, Akin, E, Alexandrino, H, Ali, S, Almeida, P, Amico, F, Ammendola, M, Andreuccetti, J, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bagnoli, C, Bains, L, Balalis, D, Baldini, E, Baraket, O, Barone, M, Barreras, J, Bellanova, G, Biancuzzi, H, Bignell, M, Bini, R, Bissacco, D, Boati, P, Bottari, A, Bouliaris, K, Brillantino, A, Buonomo, L, Buscemi, S, Calu, V, Campo Dall'Orto, R, Campostrini, S, Carvas, J, Casoni Pattacini, G, Celentano, V, Ceresoli, M, Chirica, M, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colak, E, Conti, L, Dantas Costa, S, D'Acapito, F, Damaskos, D, Das, K, Davies, R, De Beaux, A, De Simone, B, Demetrashvili, Z, Demetriades, A, Denicolai, S, Di Buono, G, Di Carlo, I, Diaconescu, B, Dibra, R, Dios-Barbeito, S, Dogjani, A, Domanin, M, D'Oria, M, Duran Munoz-Cruzado, V, East, B, Ekwen, G, Elbaih, A, Escalera-Antezana, J, Esposito, G, Farre, R, Ferrario di Tor Vajana, A, Cordeiro Fonseca, V, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Gachabayov, M, Garcia Vazquez, A, Ghannam, W, Gioco, R, Giraudo, G, Giuffrida, M, Giulii Capponi, M, Gomes, C, Teixeira Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Griffiths, E, Haidar, M, Hamid, H, Harddastle, T, Healey, A, Hecker, M, Hernandez Garcia, E, Huaman, E, Hutan, M, Ioannidis, O, Isik, A, Ismail, A, Ismail, N, Jang, J, Kaafarani, H, Kalipershad, S, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Kavalakat, A, Kechagias, A, Kenig, J, Khan, J, Khokha, V, Klappenbach, R, Kobe, Y, Kong, V, Korkolis, D, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Licari, L, Litvin, A, Loftus, T, Lohsiriwat, V, Lopes Moreira, C, Lostoridis, E, Luna, A, Luppi, D, Machain, G, Maegele, M, Maggiore, D, Maier, R, Manangi, M, Manetti, A, Mantoglu, B, Mariani, F, Marinis, A, Sbalcheiro Mariot, E, Marseglia, G, Martellucci, J, Martines, G, Martinez Perez, A, Mascagni, P, Massalou, D, Melo, R, Miceli, L, Mingoli, A, Mishra, T, Mohamedahmed, A, Mohan, R, Morales-Garcia, D, Mustafa, S, Naimzada, M, Negoi, I, Nguyen, C, Nidaw, M, Nigri, G, Ogundipe, H, Oliveri, C, Olmi, S, Pagani, L, Palomba, G, Pantalone, D, Panyko, A, Paolillo, C, Papis, D, Pararas, N, Pata, F, Paterson-Brown, S, Pavone, G, Pecchini, F, Pellino, G, Pelloni, M, Peloso, A, Perea del Pozo, E, Goncalves Pereira, R, Monteiro Pereira, B, Lizarazu Perez, A, Perrone, G, Pesce, A, Petracca, G, Piccoli, M, Piccolo, D, Picetti, E, Pikoulis, E, Pintar, T, Pirozzolo, G, Podda, M, Previtali, P, Privitera, F, Punzo, C, Quiodettis, M, Qvist, N, Rahim, R, Reinisch-Liese, A, Rodriguez-Luna, M, Roizblatt, D, Roscio, F, Rossi, S, Ruta, F, Sakakushev, B, Salamea, J, Sall, I, Sammartano, F, Sanchez Arteaga, A, Sanchez-Cordero, S, Sasia, D, Sawyer, R, Seretis, C, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Simoes, R, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Soreide, K, Spada, F, Stahel, P, Sydorchuk, L, Sydorchuk, R, Syed, A, Tallon-Aguilar, L, Tan, J, Tan, E, Tarasconi, A, Tartaglia, D, Tartaglia, N, Taylor, J, Tebala, G, Teuben, M, Tolonen, M, Tomasicchio, G, Triantafyllou, T, Trigiante, G, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Ugarte-Sierra, B, Ukkonen, M, Vassiliu, P, Verde, J, Veroux, M, Vilallonga, R, Visconti, D, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Wong, T, Xenaki, S, Yu, B, Yule, S, Zakaria, A, Zambrano, D, Zese, M, Cobianchi L., Dal Mas F., Massaro M., Biffl W., Catena F., Coccolini F., Dionigi B., Dionigi P., Di Saverio S., Fugazzola P., Kluger Y., Leppaniemi A., Moore E. E., Sartelli M., Velmahos G., Woltz S., Angelos P., Ansaloni L., Abdelmalik A., Abebe N. S., Abu-Zidan F. M., Adam Y. A. Y., Adamou H., Agrusa A., Akin E., Alexandrino H., Ali S. M., Almeida P. M., Amico F., Ammendola M., Andreuccetti J., Aparicio-Sanchez D., Ardito A., Argenio G., Askevold I. H., Atanasov B. T., Augustin G., Awad S. S., Bagnoli C., Bains L., Balalis D., Baldini E., Baraket O., Barone M., Barreras J. A., Bellanova G., Biancuzzi H., Bignell M. B., Bini R., Bissacco D., Boati P., Bottari A., Bouliaris K., Brillantino A., Buonomo L. A., Buscemi S., Calu V., Campo Dall'Orto R., Campostrini S., Carvas J. M., Casoni Pattacini G., Celentano V., Ceresoli M., Chirica M., Cianci P., Cillara N., Cimbanassi S., Cioffi S. P. B., Colak E., Conti L., Dantas Costa S., D'Acapito F., Damaskos D., Das K., Davies R. J., De Beaux A. C., De Simone B., Demetrashvili Z., Demetriades A. K., Denicolai S., Di Buono G., Di Carlo I., Diaconescu B., Dibra R., Dios-Barbeito S., Dogjani A., Domanin M., D'Oria M., Duran Munoz-Cruzado V., East B., Ekwen G. T., Elbaih A. H., Escalera-Antezana J. P., Esposito G., Farre R., Ferrario di Tor Vajana A., Cordeiro Fonseca V., Forfori F., Fortuna L., Fradelos E., Fraga G. P., Fransvea P., Gachabayov M., Garcia Vazquez A. A., Ghannam W. M., Gioco R., Giraudo G., Giuffrida M., Giulii Capponi M., Gomes C. A., Teixeira Gonsaga R. A., Gonullu E., Goosen J., Goranovic T., Griffiths E. A., Haidar M. G., Hamid H. K. S., Harddastle T. C., Healey A. J., Hecker M., Hernandez Garcia E. F., Huaman E. C., Hutan M., Ioannidis O., Isik A., Ismail A. M. H., Ismail N., Jang J. Y., Kaafarani H. M. A., Kalipershad S. N. R., Kaplan L. J., Kara Y., Karamagioli E., Karamarkovia A., Kavalakat A. J., Kechagias A., Kenig J., Khan J. S., Khokha V., Klappenbach R., Kobe Y., Kong V., Korkolis D., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Licari L., Litvin A., Loftus T. J., Lohsiriwat V., Lopes Moreira C. C., Lostoridis E., Luna A. T., Luppi D., Machain G. M., Maegele M., Maggiore D., Maier R. V., Manangi M., Manetti A., Mantoglu B., Mariani F., Marinis A., Sbalcheiro Mariot E. A., Marseglia G. R., Martellucci J., Martines G., Martinez Perez A., Mascagni P., Massalou D., Melo R. B., Miceli L., Mingoli A., Mishra T. S., Mohamedahmed A. Y. Y., Mohan R., Morales-Garcia D., Mustafa S. M. S., Naimzada M. D., Negoi I., Nguyen C., Nidaw M. K., Nigri G., Ogundipe H. D., Oliveri C., Olmi S., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papis D., Pararas N., Pata F., Paterson-Brown S., Pavone G., Pecchini F., Pellino G., Pelloni M., Peloso A., Perea del Pozo E., Goncalves Pereira R., Monteiro Pereira B., Lizarazu Perez A., Perrone G., Pesce A., Petracca G., Piccoli M., Piccolo D., Picetti E., Pikoulis E., Pintar T., Pirozzolo G., Podda M., Previtali P., Privitera F., Punzo C., Quiodettis M. A., Qvist N., Rahim R., Reinisch-Liese A., Rodriguez-Luna M. R., Roizblatt D., Roscio F. P. M., Rossi S., Ruta F., Sakakushev B. E., Salamea J. C., Sall I., Sammartano F., Sanchez Arteaga A., Sanchez-Cordero S., Sasia D., Sawyer R. G., Seretis C., Serradilla-Martin M., Shelat V. G., Shlyapnikov S., Simoes R. L., Siribumrungwong B., Slavchev M., Solaini L., Soldini G., Soreide K., Spada F., Stahel P., Sydorchuk L., Sydorchuk R., Syed A. M., Tallon-Aguilar L., Tan J. H., Tan E., Tarasconi A., Tartaglia D., Tartaglia N., Taylor J., Tebala G. D., Teuben M., Tolonen M., Tomasicchio G., Triantafyllou T., Trigiante G., Turrado-Rodriguez V., Tutino R., Uccelli M., Ugarte-Sierra B., Ukkonen M., Vassiliu P. G., Verde J. M., Veroux M., Vilallonga R., Visconti D., Waledziak M., Wannatoop T., Widmer L. W., Wilson M. S. J., Wong T. H., Xenaki S., Yu B., Yule S., Zakaria A. D., Zambrano D. A., Zese M., Cobianchi, L, Dal Mas, F, Massaro, M, Biffl, W, Catena, F, Coccolini, F, Dionigi, B, Dionigi, P, Di Saverio, S, Fugazzola, P, Kluger, Y, Leppaniemi, A, Moore, E, Sartelli, M, Velmahos, G, Woltz, S, Angelos, P, Ansaloni, L, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Agrusa, A, Akin, E, Alexandrino, H, Ali, S, Almeida, P, Amico, F, Ammendola, M, Andreuccetti, J, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bagnoli, C, Bains, L, Balalis, D, Baldini, E, Baraket, O, Barone, M, Barreras, J, Bellanova, G, Biancuzzi, H, Bignell, M, Bini, R, Bissacco, D, Boati, P, Bottari, A, Bouliaris, K, Brillantino, A, Buonomo, L, Buscemi, S, Calu, V, Campo Dall'Orto, R, Campostrini, S, Carvas, J, Casoni Pattacini, G, Celentano, V, Ceresoli, M, Chirica, M, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colak, E, Conti, L, Dantas Costa, S, D'Acapito, F, Damaskos, D, Das, K, Davies, R, De Beaux, A, De Simone, B, Demetrashvili, Z, Demetriades, A, Denicolai, S, Di Buono, G, Di Carlo, I, Diaconescu, B, Dibra, R, Dios-Barbeito, S, Dogjani, A, Domanin, M, D'Oria, M, Duran Munoz-Cruzado, V, East, B, Ekwen, G, Elbaih, A, Escalera-Antezana, J, Esposito, G, Farre, R, Ferrario di Tor Vajana, A, Cordeiro Fonseca, V, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Gachabayov, M, Garcia Vazquez, A, Ghannam, W, Gioco, R, Giraudo, G, Giuffrida, M, Giulii Capponi, M, Gomes, C, Teixeira Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Griffiths, E, Haidar, M, Hamid, H, Harddastle, T, Healey, A, Hecker, M, Hernandez Garcia, E, Huaman, E, Hutan, M, Ioannidis, O, Isik, A, Ismail, A, Ismail, N, Jang, J, Kaafarani, H, Kalipershad, S, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Kavalakat, A, Kechagias, A, Kenig, J, Khan, J, Khokha, V, Klappenbach, R, Kobe, Y, Kong, V, Korkolis, D, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Licari, L, Litvin, A, Loftus, T, Lohsiriwat, V, Lopes Moreira, C, Lostoridis, E, Luna, A, Luppi, D, Machain, G, Maegele, M, Maggiore, D, Maier, R, Manangi, M, Manetti, A, Mantoglu, B, Mariani, F, Marinis, A, Sbalcheiro Mariot, E, Marseglia, G, Martellucci, J, Martines, G, Martinez Perez, A, Mascagni, P, Massalou, D, Melo, R, Miceli, L, Mingoli, A, Mishra, T, Mohamedahmed, A, Mohan, R, Morales-Garcia, D, Mustafa, S, Naimzada, M, Negoi, I, Nguyen, C, Nidaw, M, Nigri, G, Ogundipe, H, Oliveri, C, Olmi, S, Pagani, L, Palomba, G, Pantalone, D, Panyko, A, Paolillo, C, Papis, D, Pararas, N, Pata, F, Paterson-Brown, S, Pavone, G, Pecchini, F, Pellino, G, Pelloni, M, Peloso, A, Perea del Pozo, E, Goncalves Pereira, R, Monteiro Pereira, B, Lizarazu Perez, A, Perrone, G, Pesce, A, Petracca, G, Piccoli, M, Piccolo, D, Picetti, E, Pikoulis, E, Pintar, T, Pirozzolo, G, Podda, M, Previtali, P, Privitera, F, Punzo, C, Quiodettis, M, Qvist, N, Rahim, R, Reinisch-Liese, A, Rodriguez-Luna, M, Roizblatt, D, Roscio, F, Rossi, S, Ruta, F, Sakakushev, B, Salamea, J, Sall, I, Sammartano, F, Sanchez Arteaga, A, Sanchez-Cordero, S, Sasia, D, Sawyer, R, Seretis, C, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Simoes, R, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Soreide, K, Spada, F, Stahel, P, Sydorchuk, L, Sydorchuk, R, Syed, A, Tallon-Aguilar, L, Tan, J, Tan, E, Tarasconi, A, Tartaglia, D, Tartaglia, N, Taylor, J, Tebala, G, Teuben, M, Tolonen, M, Tomasicchio, G, Triantafyllou, T, Trigiante, G, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Ugarte-Sierra, B, Ukkonen, M, Vassiliu, P, Verde, J, Veroux, M, Vilallonga, R, Visconti, D, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Wong, T, Xenaki, S, Yu, B, Yule, S, Zakaria, A, Zambrano, D, Zese, M, Cobianchi L., Dal Mas F., Massaro M., Biffl W., Catena F., Coccolini F., Dionigi B., Dionigi P., Di Saverio S., Fugazzola P., Kluger Y., Leppaniemi A., Moore E. E., Sartelli M., Velmahos G., Woltz S., Angelos P., Ansaloni L., Abdelmalik A., Abebe N. S., Abu-Zidan F. M., Adam Y. A. Y., Adamou H., Agrusa A., Akin E., Alexandrino H., Ali S. M., Almeida P. M., Amico F., Ammendola M., Andreuccetti J., Aparicio-Sanchez D., Ardito A., Argenio G., Askevold I. H., Atanasov B. T., Augustin G., Awad S. S., Bagnoli C., Bains L., Balalis D., Baldini E., Baraket O., Barone M., Barreras J. A., Bellanova G., Biancuzzi H., Bignell M. B., Bini R., Bissacco D., Boati P., Bottari A., Bouliaris K., Brillantino A., Buonomo L. A., Buscemi S., Calu V., Campo Dall'Orto R., Campostrini S., Carvas J. M., Casoni Pattacini G., Celentano V., Ceresoli M., Chirica M., Cianci P., Cillara N., Cimbanassi S., Cioffi S. P. B., Colak E., Conti L., Dantas Costa S., D'Acapito F., Damaskos D., Das K., Davies R. J., De Beaux A. C., De Simone B., Demetrashvili Z., Demetriades A. K., Denicolai S., Di Buono G., Di Carlo I., Diaconescu B., Dibra R., Dios-Barbeito S., Dogjani A., Domanin M., D'Oria M., Duran Munoz-Cruzado V., East B., Ekwen G. T., Elbaih A. H., Escalera-Antezana J. P., Esposito G., Farre R., Ferrario di Tor Vajana A., Cordeiro Fonseca V., Forfori F., Fortuna L., Fradelos E., Fraga G. P., Fransvea P., Gachabayov M., Garcia Vazquez A. A., Ghannam W. M., Gioco R., Giraudo G., Giuffrida M., Giulii Capponi M., Gomes C. A., Teixeira Gonsaga R. A., Gonullu E., Goosen J., Goranovic T., Griffiths E. A., Haidar M. G., Hamid H. K. S., Harddastle T. C., Healey A. J., Hecker M., Hernandez Garcia E. F., Huaman E. C., Hutan M., Ioannidis O., Isik A., Ismail A. M. H., Ismail N., Jang J. Y., Kaafarani H. M. A., Kalipershad S. N. R., Kaplan L. J., Kara Y., Karamagioli E., Karamarkovia A., Kavalakat A. J., Kechagias A., Kenig J., Khan J. S., Khokha V., Klappenbach R., Kobe Y., Kong V., Korkolis D., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Licari L., Litvin A., Loftus T. J., Lohsiriwat V., Lopes Moreira C. C., Lostoridis E., Luna A. T., Luppi D., Machain G. M., Maegele M., Maggiore D., Maier R. V., Manangi M., Manetti A., Mantoglu B., Mariani F., Marinis A., Sbalcheiro Mariot E. A., Marseglia G. R., Martellucci J., Martines G., Martinez Perez A., Mascagni P., Massalou D., Melo R. B., Miceli L., Mingoli A., Mishra T. S., Mohamedahmed A. Y. Y., Mohan R., Morales-Garcia D., Mustafa S. M. S., Naimzada M. D., Negoi I., Nguyen C., Nidaw M. K., Nigri G., Ogundipe H. D., Oliveri C., Olmi S., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papis D., Pararas N., Pata F., Paterson-Brown S., Pavone G., Pecchini F., Pellino G., Pelloni M., Peloso A., Perea del Pozo E., Goncalves Pereira R., Monteiro Pereira B., Lizarazu Perez A., Perrone G., Pesce A., Petracca G., Piccoli M., Piccolo D., Picetti E., Pikoulis E., Pintar T., Pirozzolo G., Podda M., Previtali P., Privitera F., Punzo C., Quiodettis M. A., Qvist N., Rahim R., Reinisch-Liese A., Rodriguez-Luna M. R., Roizblatt D., Roscio F. P. M., Rossi S., Ruta F., Sakakushev B. E., Salamea J. C., Sall I., Sammartano F., Sanchez Arteaga A., Sanchez-Cordero S., Sasia D., Sawyer R. G., Seretis C., Serradilla-Martin M., Shelat V. G., Shlyapnikov S., Simoes R. L., Siribumrungwong B., Slavchev M., Solaini L., Soldini G., Soreide K., Spada F., Stahel P., Sydorchuk L., Sydorchuk R., Syed A. M., Tallon-Aguilar L., Tan J. H., Tan E., Tarasconi A., Tartaglia D., Tartaglia N., Taylor J., Tebala G. D., Teuben M., Tolonen M., Tomasicchio G., Triantafyllou T., Trigiante G., Turrado-Rodriguez V., Tutino R., Uccelli M., Ugarte-Sierra B., Ukkonen M., Vassiliu P. G., Verde J. M., Veroux M., Vilallonga R., Visconti D., Waledziak M., Wannatoop T., Widmer L. W., Wilson M. S. J., Wong T. H., Xenaki S., Yu B., Yule S., Zakaria A. D., Zambrano D. A., and Zese M.
- Abstract
Background: Investigating the context of trauma and acute care surgery, the article aims at understanding the factors that can enhance some ethical aspects, namely the importance of patient consent, the perceptiveness of the ethical role of the trauma leader, and the perceived importance of ethics as an educational subject. Methods: The article employs an international questionnaire promoted by the World Society of Emergency Surgery. Results: Through the analysis of 402 fully filled questionnaires by surgeons from 72 different countries, the three main ethical topics are investigated through the lens of gender, membership of an academic or non-academic institution, an official trauma team, and a diverse group. In general terms, results highlight greater attention paid by surgeons belonging to academic institutions, official trauma teams, and diverse groups. Conclusions: Our results underline that some organizational factors (e.g., the fact that the team belongs to a university context or is more diverse) might lead to the development of a higher sensibility on ethical matters. Embracing cultural diversity forces trauma teams to deal with different mindsets. Organizations should, therefore, consider those elements in defining their organizational procedures. Level of evidence: Trauma and acute care teams work under tremendous pressure and complex circumstances, with their members needing to make ethical decisions quickly. The international survey allowed to shed light on how team assembly decisions might represent an opportunity to coordinate team member actions and increase performance.
- Published
- 2022
20. Diversity and ethics in trauma and acute care surgery teams: results from an international survey
- Author
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Cobianchi L., Dal Mas F., Massaro M., Biffl W., Catena F., Coccolini F., Dionigi B., Dionigi P., Di Saverio S., Fugazzola P., Kluger Y., Leppaniemi A., Moore E. E., Sartelli M., Velmahos G., Woltz S., Angelos P., Ansaloni L., Abdelmalik A., Abebe N. S., Abu-Zidan F. M., Adam Y. A. Y., Adamou H., Agrusa A., Akin E., Alexandrino H., Ali S. M., Almeida P. M., Amico F., Ammendola M., Andreuccetti J., Aparicio-Sanchez D., Ardito A., Argenio G., Askevold I. H., Atanasov B. T., Augustin G., Awad S. S., Bagnoli C., Bains L., Balalis D., Baldini E., Baraket O., Barone M., Barreras J. A., Bellanova G., Biancuzzi H., Bignell M. B., Bini R., Bissacco D., Boati P., Bottari A., Bouliaris K., Brillantino A., Buonomo L. A., Buscemi S., Calu V., Campo Dall'Orto R., Campostrini S., Carvas J. M., Casoni Pattacini G., Celentano V., Ceresoli M., Chirica M., Cianci P., Cillara N., Cimbanassi S., Cioffi S. P. B., Colak E., Conti L., Dantas Costa S., D'Acapito F., Damaskos D., Das K., Davies R. J., De Beaux A. C., De Simone B., Demetrashvili Z., Demetriades A. K., Denicolai S., Di Buono G., Di Carlo I., Diaconescu B., Dibra R., Dios-Barbeito S., Dogjani A., Domanin M., D'Oria M., Duran Munoz-Cruzado V., East B., Ekwen G. T., Elbaih A. H., Escalera-Antezana J. P., Esposito G., Farre R., Ferrario di Tor Vajana A., Cordeiro Fonseca V., Forfori F., Fortuna L., Fradelos E., Fraga G. P., Fransvea P., Gachabayov M., Garcia Vazquez A. A., Ghannam W. M., Gioco R., Giraudo G., Giuffrida M., Giulii Capponi M., Gomes C. A., Teixeira Gonsaga R. A., Gonullu E., Goosen J., Goranovic T., Griffiths E. A., Haidar M. G., Hamid H. K. S., Harddastle T. C., Healey A. J., Hecker M., Hernandez Garcia E. F., Huaman E. C., Hutan M., Ioannidis O., Isik A., Ismail A. M. H., Ismail N., Jang J. Y., Kaafarani H. M. A., Kalipershad S. N. R., Kaplan L. J., Kara Y., Karamagioli E., Karamarkovia A., Kavalakat A. J., Kechagias A., Kenig J., Khan J. S., Khokha V., Klappenbach R., Kobe Y., Kong V., Korkolis D., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Licari L., Litvin A., Loftus T. J., Lohsiriwat V., Lopes Moreira C. C., Lostoridis E., Luna A. T., Luppi D., Machain G. M., Maegele M., Maggiore D., Maier R. V., Manangi M., Manetti A., Mantoglu B., Mariani F., Marinis A., Sbalcheiro Mariot E. A., Marseglia G. R., Martellucci J., Martines G., Martinez Perez A., Mascagni P., Massalou D., Melo R. B., Miceli L., Mingoli A., Mishra T. S., Mohamedahmed A. Y. Y., Mohan R., Morales-Garcia D., Mustafa S. M. S., Naimzada M. D., Negoi I., Nguyen C., Nidaw M. K., Nigri G., Ogundipe H. D., Oliveri C., Olmi S., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papis D., Pararas N., Pata F., Paterson-Brown S., Pavone G., Pecchini F., Pellino G., Pelloni M., Peloso A., Perea del Pozo E., Goncalves Pereira R., Monteiro Pereira B., Lizarazu Perez A., Perrone G., Pesce A., Petracca G., Piccoli M., Piccolo D., Picetti E., Pikoulis E., Pintar T., Pirozzolo G., Podda M., Previtali P., Privitera F., Punzo C., Quiodettis M. A., Qvist N., Rahim R., Reinisch-Liese A., Rodriguez-Luna M. R., Roizblatt D., Roscio F. P. M., Rossi S., Ruta F., Sakakushev B. E., Salamea J. C., Sall I., Sammartano F., Sanchez Arteaga A., Sanchez-Cordero S., Sasia D., Sawyer R. G., Seretis C., Serradilla-Martin M., Shelat V. G., Shlyapnikov S., Simoes R. L., Siribumrungwong B., Slavchev M., Solaini L., Soldini G., Soreide K., Spada F., Stahel P., Sydorchuk L., Sydorchuk R., Syed A. M., Tallon-Aguilar L., Tan J. H., Tan E., Tarasconi A., Tartaglia D., Tartaglia N., Taylor J., Tebala G. D., Teuben M., Tolonen M., Tomasicchio G., Triantafyllou T., Trigiante G., Turrado-Rodriguez V., Tutino R., Uccelli M., Ugarte-Sierra B., Ukkonen M., Vassiliu P. G., Verde J. M., Veroux M., Vilallonga R., Visconti D., Waledziak M., Wannatoop T., Widmer L. W., Wilson M. S. J., Wong T. H., Xenaki S., Yu B., Yule S., Zakaria A. D., Zambrano D. A., Zese M., Cobianchi, L, Dal Mas, F, Massaro, M, Biffl, W, Catena, F, Coccolini, F, Dionigi, B, Dionigi, P, Di Saverio, S, Fugazzola, P, Kluger, Y, Leppaniemi, A, Moore, E, Sartelli, M, Velmahos, G, Woltz, S, Angelos, P, Ansaloni, L, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Agrusa, A, Akin, E, Alexandrino, H, Ali, S, Almeida, P, Amico, F, Ammendola, M, Andreuccetti, J, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bagnoli, C, Bains, L, Balalis, D, Baldini, E, Baraket, O, Barone, M, Barreras, J, Bellanova, G, Biancuzzi, H, Bignell, M, Bini, R, Bissacco, D, Boati, P, Bottari, A, Bouliaris, K, Brillantino, A, Buonomo, L, Buscemi, S, Calu, V, Campo Dall'Orto, R, Campostrini, S, Carvas, J, Casoni Pattacini, G, Celentano, V, Ceresoli, M, Chirica, M, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colak, E, Conti, L, Dantas Costa, S, D'Acapito, F, Damaskos, D, Das, K, Davies, R, De Beaux, A, De Simone, B, Demetrashvili, Z, Demetriades, A, Denicolai, S, Di Buono, G, Di Carlo, I, Diaconescu, B, Dibra, R, Dios-Barbeito, S, Dogjani, A, Domanin, M, D'Oria, M, Duran Munoz-Cruzado, V, East, B, Ekwen, G, Elbaih, A, Escalera-Antezana, J, Esposito, G, Farre, R, Ferrario di Tor Vajana, A, Cordeiro Fonseca, V, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Gachabayov, M, Garcia Vazquez, A, Ghannam, W, Gioco, R, Giraudo, G, Giuffrida, M, Giulii Capponi, M, Gomes, C, Teixeira Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Griffiths, E, Haidar, M, Hamid, H, Harddastle, T, Healey, A, Hecker, M, Hernandez Garcia, E, Huaman, E, Hutan, M, Ioannidis, O, Isik, A, Ismail, A, Ismail, N, Jang, J, Kaafarani, H, Kalipershad, S, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Kavalakat, A, Kechagias, A, Kenig, J, Khan, J, Khokha, V, Klappenbach, R, Kobe, Y, Kong, V, Korkolis, D, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Licari, L, Litvin, A, Loftus, T, Lohsiriwat, V, Lopes Moreira, C, Lostoridis, E, Luna, A, Luppi, D, Machain, G, Maegele, M, Maggiore, D, Maier, R, Manangi, M, Manetti, A, Mantoglu, B, Mariani, F, Marinis, A, Sbalcheiro Mariot, E, Marseglia, G, Martellucci, J, Martines, G, Martinez Perez, A, Mascagni, P, Massalou, D, Melo, R, Miceli, L, Mingoli, A, Mishra, T, Mohamedahmed, A, Mohan, R, Morales-Garcia, D, Mustafa, S, Naimzada, M, Negoi, I, Nguyen, C, Nidaw, M, Nigri, G, Ogundipe, H, Oliveri, C, Olmi, S, Pagani, L, Palomba, G, Pantalone, D, Panyko, A, Paolillo, C, Papis, D, Pararas, N, Pata, F, Paterson-Brown, S, Pavone, G, Pecchini, F, Pellino, G, Pelloni, M, Peloso, A, Perea del Pozo, E, Goncalves Pereira, R, Monteiro Pereira, B, Lizarazu Perez, A, Perrone, G, Pesce, A, Petracca, G, Piccoli, M, Piccolo, D, Picetti, E, Pikoulis, E, Pintar, T, Pirozzolo, G, Podda, M, Previtali, P, Privitera, F, Punzo, C, Quiodettis, M, Qvist, N, Rahim, R, Reinisch-Liese, A, Rodriguez-Luna, M, Roizblatt, D, Roscio, F, Rossi, S, Ruta, F, Sakakushev, B, Salamea, J, Sall, I, Sammartano, F, Sanchez Arteaga, A, Sanchez-Cordero, S, Sasia, D, Sawyer, R, Seretis, C, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Simoes, R, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Soreide, K, Spada, F, Stahel, P, Sydorchuk, L, Sydorchuk, R, Syed, A, Tallon-Aguilar, L, Tan, J, Tan, E, Tarasconi, A, Tartaglia, D, Tartaglia, N, Taylor, J, Tebala, G, Teuben, M, Tolonen, M, Tomasicchio, G, Triantafyllou, T, Trigiante, G, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Ugarte-Sierra, B, Ukkonen, M, Vassiliu, P, Verde, J, Veroux, M, Vilallonga, R, Visconti, D, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Wong, T, Xenaki, S, Yu, B, Yule, S, Zakaria, A, Zambrano, D, Zese, M, Cobianchi L., Dal Mas F., Massaro M., Biffl W., Catena F., Coccolini F., Dionigi B., Dionigi P., Di Saverio S., Fugazzola P., Kluger Y., Leppaniemi A., Moore E.E., Sartelli M., Velmahos G., Woltz S., Angelos P., Ansaloni L., Abdelmalik A., Abebe N.S., Abu-Zidan F.M., Adam Y.A.Y., Adamou H., Agrusa A., Akin E., Alexandrino H., Ali S.M., Almeida P.M., Amico F., Ammendola M., Andreuccetti J., Aparicio-Sanchez D., Ardito A., Argenio G., Askevold I.H., Atanasov B.T., Augustin G., Awad S.S., Bagnoli C., Bains L., Balalis D., Baldini E., Baraket O., Barone M., Barreras J.A., Bellanova G., Biancuzzi H., Bignell M.B., Bini R., Bissacco D., Boati P., Bottari A., Bouliaris K., Brillantino A., Buonomo L.A., Buscemi S., Calu V., Campo Dall'Orto R., Campostrini S., Carvas J.M., Casoni Pattacini G., Celentano V., Ceresoli M., Chirica M., Cianci P., Cillara N., Cimbanassi S., Cioffi S.P.B., Colak E., Conti L., Dantas Costa S., D'Acapito F., Damaskos D., Das K., Davies R.J., De Beaux A.C., De Simone B., Demetrashvili Z., Demetriades A.K., Denicolai S., Di Buono G., Di Carlo I., Diaconescu B., Dibra R., Dios-Barbeito S., Dogjani A., Domanin M., D'Oria M., Duran Munoz-Cruzado V., East B., Ekwen G.T., Elbaih A.H., Escalera-Antezana J.P., Esposito G., Farre R., Ferrario di Tor Vajana A., Cordeiro Fonseca V., Forfori F., Fortuna L., Fradelos E., Fraga G.P., Fransvea P., Gachabayov M., Garcia Vazquez A.A., Ghannam W.M., Gioco R., Giraudo G., Giuffrida M., Giulii Capponi M., Gomes C.A., Teixeira Gonsaga R.A., Gonullu E., Goosen J., Goranovic T., Griffiths E.A., Haidar M.G., Hamid H.K.S., Harddastle T.C., Healey A.J., Hecker M., Hernandez Garcia E.F., Huaman E.C., Hutan M., Ioannidis O., Isik A., Ismail A.M.H., Ismail N., Jang J.Y., Kaafarani H.M.A., Kalipershad S.N.R., Kaplan L.J., Kara Y., Karamagioli E., Karamarkovia A., Kavalakat A.J., Kechagias A., Kenig J., Khan J.S., Khokha V., Klappenbach R., Kobe Y., Kong V., Korkolis D., Kurihara H., Kuriyama A., Landaluce-Olavarria A., Licari L., Litvin A., Loftus T.J., Lohsiriwat V., Lopes Moreira C.C., Lostoridis E., Luna A.T., Luppi D., Machain G.M., Maegele M., Maggiore D., Maier R.V., Manangi M., Manetti A., Mantoglu B., Mariani F., Marinis A., Sbalcheiro Mariot E.A., Marseglia G.R., Martellucci J., Martines G., Martinez Perez A., Mascagni P., Massalou D., Melo R.B., Miceli L., Mingoli A., Mishra T.S., Mohamedahmed A.Y.Y., Mohan R., Morales-Garcia D., Mustafa S.M.S., Naimzada M.D., Negoi I., Nguyen C., Nidaw M.K., Nigri G., Ogundipe H.D., Oliveri C., Olmi S., Pagani L., Palomba G., Pantalone D., Panyko A., Paolillo C., Papis D., Pararas N., Pata F., Paterson-Brown S., Pavone G., Pecchini F., Pellino G., Pelloni M., Peloso A., Perea del Pozo E., Goncalves Pereira R., Monteiro Pereira B., Lizarazu Perez A., Perrone G., Pesce A., Petracca G., Piccoli M., Piccolo D., Picetti E., Pikoulis E., Pintar T., Pirozzolo G., Podda M., Previtali P., Privitera F., Punzo C., Quiodettis M.A., Qvist N., Rahim R., Reinisch-Liese A., Rodriguez-Luna M.R., Roizblatt D., Roscio F.P.M., Rossi S., Ruta F., Sakakushev B.E., Salamea J.C., Sall I., Sammartano F., Sanchez Arteaga A., Sanchez-Cordero S., Sasia D., Sawyer R.G., Seretis C., Serradilla-Martin M., Shelat V.G., Shlyapnikov S., Simoes R.L., Siribumrungwong B., Slavchev M., Solaini L., Soldini G., Soreide K., Spada F., Stahel P., Sydorchuk L., Sydorchuk R., Syed A.M., Tallon-Aguilar L., Tan J.H., Tan E., Tarasconi A., Tartaglia D., Tartaglia N., Taylor J., Tebala G.D., Teuben M., Tolonen M., Tomasicchio G., Triantafyllou T., Trigiante G., Turrado-Rodriguez V., Tutino R., Uccelli M., Ugarte-Sierra B., Ukkonen M., Vassiliu P.G., Verde J.M., Veroux M., Vilallonga R., Visconti D., Waledziak M., Wannatoop T., Widmer L.W., Wilson M.S.J., Wong T.H., Xenaki S., Yu B., Yule S., Zakaria A.D., Zambrano D.A., Zese M., HUS Abdominal Center, II kirurgian klinikka, and Helsinki University Hospital Area
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Ethics ,Patient Care Team ,Diversity ,Acute care surgery ,3126 Surgery, anesthesiology, intensive care, radiology ,Trauma surgery ,Settore SECS-P/10 - Organizzazione Aziendale ,Settore MED/18 - Chirurgia Generale ,Settore SECS-P/07 - Economia Aziendale ,Surveys and Questionnaires ,Emergency Medicine ,Humans ,Surveys and Questionnaire ,Surgery ,Team dynamics ,Ethic ,Team dynamic ,Human - Abstract
Background Investigating the context of trauma and acute care surgery, the article aims at understanding the factors that can enhance some ethical aspects, namely the importance of patient consent, the perceptiveness of the ethical role of the trauma leader, and the perceived importance of ethics as an educational subject. Methods The article employs an international questionnaire promoted by the World Society of Emergency Surgery. Results Through the analysis of 402 fully filled questionnaires by surgeons from 72 different countries, the three main ethical topics are investigated through the lens of gender, membership of an academic or non-academic institution, an official trauma team, and a diverse group. In general terms, results highlight greater attention paid by surgeons belonging to academic institutions, official trauma teams, and diverse groups. Conclusions Our results underline that some organizational factors (e.g., the fact that the team belongs to a university context or is more diverse) might lead to the development of a higher sensibility on ethical matters. Embracing cultural diversity forces trauma teams to deal with different mindsets. Organizations should, therefore, consider those elements in defining their organizational procedures. Level of evidence Trauma and acute care teams work under tremendous pressure and complex circumstances, with their members needing to make ethical decisions quickly. The international survey allowed to shed light on how team assembly decisions might represent an opportunity to coordinate team member actions and increase performance.
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- 2022
21. Stingless Bees (Melipona subnitida) Overcome Severe Drought Events in the Brazilian Tropical Dry Forest by Opting for High-Profit Food Sources
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Maia-Silva, Camila, Limão, A. A. C., Silva, C. I., Imperatriz-Fonseca, V. L., and Hrncir, M.
- Abstract
In the Brazilian Tropical Dry Forest, the Caatinga, stingless bees (Apidae, Meliponini) need to adjust their foraging behavior to a very short and unpredictable blooming period. Melipona subnitidaDucke 1910 is one of the few meliponine species adapted to the environmental peculiarities of this biome. To get an insight into how these highly eusocial bees are able to maintain their perennial colonies despite extended periods of food scarcity, we asked the following questions: (1) At which plant species do colonies of M. subnitidacollect their food during the rainy season? And (2) are there any plant species during the dry season, from which the colonies may profit for replenishing their food stores? During 1 year, we collected monthly honey and pollen samples from recently built storage pots of five colonies of M. subnitidaand identified the botanical origin of the collected resources. In the course of our study, the colonies foraged at native trees, shrubs, and herbaceous species, demonstrating the importance of all plant strata for the bees’ diet. Profitable plants, which bloom mainly during the rainy season and usually produce a great number of flowers, were frequently sampled in new pots throughout the entire study, even during the dry season. From our results, we compiled a list of the most important plant species providing floral resources for bees throughout the year, including periods of drought. We recommend these plants for restoration areas to improve the conservation of native bee species and local beekeeping in the Brazilian Tropical Dry Forest.
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- 2024
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22. Risk of diabetic retinopathy in women with normal and early age menopause in the atherosclerosis risk in communities (ARIC) study
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Gandhi, P, primary, Chen, Z, additional, Yoshida, Y, additional, and Fonseca, V, additional
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- 2023
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23. Risks and opportunities associated with pollinators’ conservation and management of pollination services in Latin America
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GALETTO, L., AIZEN, M. A., ARIZMENDI, M. del C., FREITAS, B. M., GARIBALDI, L. A., GIANNINI, T. C., LOPES, A. V., ESPÍEIRTO SANTO, M. M. do, MAUES, M. M., NATES-PARRA, G., RODRIGUEZ, J. I., QUEZADA-EUAN, J. J. G., VANDAME, R., VIANA, B. F., IMPERATRIZ-FONSECA, V. L., LEONARDO GALETTO, Universidad Nacional de Córdoba, MARCELO A. AIZEN, Universidad Nacional del Comahue, M. DEL CORO ARIZMENDI, Universidad Nacional Autónoma de México, BRENO M. FREITAS, UFC, LUCAS A. GARIBALDI, Universidad Nacional de Río Negro, TEREZA C. GIANNINI, Instituto Tecnológico Vale Desenvolvimento Sustentavel, ARIADNA V. LOPES, UFPE, MÁRIO M. DO ESPÍRITO SANTO, Universidade Estadual de Montes Claros, MARCIA MOTTA MAUES, CPATU, GUIOMAR NATES-PARRA, Universidad Nacional de Colombia, JAIME I. RODRIGUEZ, Museo Nacional de Historia Natural de Bolivia, JOSÉ J. G. QUEZADA-EUAN, Universidad Autónoma de Yucatán, REMY VANDAME, El Colegio de la Frontera Sur, BLANDINA F. VIANA, UFBA, and VERA LUCIA IMPERATRIZ-FONSECA, Instituto Tecnológico Vale Desenvolvimento Sustentavel.
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Política Ambiental ,Ecology ,Environmental Policies ,Biodiversidade ,Serviços de polinização ,Biodiversity ,Ecología ,Agricultura (General) ,Pollination Services ,Traditional Local Knowledge ,Polinização ,Déficit de polinização ,Inseto Polinizador ,Conhecimento local tradicional ,Biodiversidad y Conservación ,Pollination Deficit ,Ecology, Evolution, Behavior and Systematics ,Declínio de polinizadores ,Pollinator Decline - Abstract
Fil: Galetto, Leonardo. Universidad Nacional de Córdoba. Córdoba, Argentina. Fil: Aizen, Marcelo A. Universidad Nacional del Comahue. Instituto de Investigaciones en Biodiversidad y Medioambiente. Rio Negro, Argentina. Fil: Arizmendi, María del Coro. Universidad Nacional Autónoma de México. México. Fil: Freitas, Breno M. Universidade Federal do Ceará. Brasil. Fil: Garibaldi, Lucas A. Universidad Nacional de Río Negro. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Garibaldi, Lucas A. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Giannini, Tereza C. Instituto Tecnológico Vale Desenvolvimento Sustentavel. Brasil. Fil: Lopes, Ariadna V. Universidade Federal de Pernambuco. Brasil. Fil: Do Espírito Santo, Mário M. Universidade Estadual de Montes Claros. Brasil. Fil: Maués, Márcia M. Embrapa Amazônia Oriental. Brasil. Fil: Nates-Parra, Guiomar. Universidad Nacional de Colombia. Colombia. Fil: Rodríguez, Jaime I. Museo Nacional de Historia Natural de Bolivia. Bolivia. Fil: Quezada-Euán, José J. G. Universidad Autónoma de Yucatán. México. Fil: Vandame, Remy. El Colegio de la Frontera Sur. México. Fil: Viana, Blandina F. Universidade Federal da Bahia. Brasil. Fil: Imperatriz-Fonseca, Vera L. Instituto Tecnológico Vale Desenvolvimento Sustentavel. Brasil. The conservation status of pollinators and pollination in Latin America (LA) is reviewed. The knowledge regarding native and managed pollinators (e.g., honeybee and stingless bees) and pollination services was synthetized, and the guidelines to improve the opportunities for conservation are provided, considering the threats to pollinators and the perspectives from traditional and local knowledge. The analysis indicates that diverse threats (e.g., large-scale agriculture, deforestation, overuse of agrochemicals) are linked with pollination and pollinator decline, which affect the reproduction of most native plants and the yields of many crops. LA harbours the highest bee diversity worldwide, with 26% of the total recorded species, and it is a biodiversity hotspot of vertebrate pollinators, including hummingbirds, perching birds, nectarivorous bats and other mammal pollinators. Specific recommendations to conserve native pollinators and to improve pollination services are provided, which could be considered by stakeholders and governments aiming to elaborate biocultural conservation. For example, introducing policies and legal responses for incentives to help farmers maintain natural habitats and forests, to replace or reduce agrochemicals and to improve diversified crop production with agroecological practices; refining agrochemical regulations to minimize the exposure of pollinators to insecticides and herbicides; improving knowledge and education on pollinators and pollination gives societies worldwide the opportunity to change current hegemonic agricultural practices and consumption paerns; integrating different land ethical views of ethnic minorities on a sustainable relationship between production and biodiversity. A wider view combining social, ecological, cultural dimensions may support beer decision making. This holistic socio-agroecological perspective is urgently needed to conserve and manage pollinators at different spatial and temporal scales, and to integrate pollination services, pollinator-friendly habitat management approaches and diversified farming systems. Se realizó una revisión sobre el estado de conservación de los polinizadores y la polinización en América Latina (LA). Se presentan pautas para mejorar las oportunidades de conservación, considerando las amenazas a los polinizadores y las perspectivas desde el conocimiento tradicional y local. El análisis indica que diversas amenazas (e.g., agricultura a gran escala, deforestación, uso excesivo de agroquímicos) están vinculadas con la disminución de polinizadores, afectando la reproducción de las plantas nativas y los rendimientos de muchos cultivos. LA alberga la mayor diversidad de abejas en todo el mundo y una gran diversidad de polinizadores vertebrados (e.g., colibríes, aves de percha nectarívoras, murciélagos nectarívoros y otros mamíferos). Se proporcionan recomendaciones para proteger los polinizadores nativos y mejorar los servicios de polinización, las que podrían ser consideradas por los tomadores de decisiones y así promover la conservación biocultural. Por ejemplo, desarrollar instrumentos legales, políticas e incentivos para ayudar a los agricultores a mantener los hábitats naturales, para reemplazar o reducir el uso de agroquímicos y para promover las prácticas agroecológicas; perfeccionar las reglamentaciones sobre aplicación de agroquímicos para minimizar la exposición de los polinizadores a insecticidas y herbicidas; mejorar la comunicación pública del conocimiento sobre los polinizadores y la polinización para incentivar un cambio en las prácticas agrícolas hegemónicas y los patrones de consumo actuales; considerar otras éticas ambientales de las minorías étnicas para enfatizar la necesidad de promover una relación sostenible entre producción de alimentos y biodiversidad. Se necesita urgentemente una visión más amplia que combine las dimensiones sociales, ecológicas y culturales para una mejor toma de decisiones. Esta perspectiva socio-agroecológica holística es importante para conservar y gestionar los polinizadores a diferentes escalas espaciales y temporales, y para poder integrar los servicios de polinización con enfoques de gestión del territorio favorables a los polinizadores y con sistemas agrícolas diversificados.
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- 2022
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24. Cell Viability Multiplexing: Quantification of Cellular Viability by Barcode Flow Cytometry and Computational Analysis
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Giudice, V., Fonseca, V., Selleri, C., and Gadina, M.
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Fixable dyes ,Flow cytometry ,Fluorescent cell barcoding ,Multiplexing ,Viability - Published
- 2023
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25. MSR56 Evaluating the Impact of Using Different Risk Equations for Cost-Effectiveness Evaluation in the US Setting
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Valentine, W, primary, Hoog, M, additional, Belger, M, additional, Mody, R, additional, Pollock, RF, additional, Shi, L, additional, and Fonseca, V, additional
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- 2022
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26. RWD113 A Novel Risk Engine for Diabetes-Related Complications Among Individuals with Type 1 Diabetes in the US
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Tang, T, primary, Fonseca, V, additional, Shao, H, additional, and Shi, L, additional
- Published
- 2022
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27. IDF21-0428 7-year Simulation of Clinical Outcomes In People With Type 2 Diabetes Treated With Insulin Glargine 300 U/mL vs 100 U/mL
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Shao, H., Shi, L., Fonseca, V., Alsaleh, A.J.O., Gill, J., and Charlie, N.
- Published
- 2022
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28. EE139 Intensification with Insulin Glargine 300 U/Ml (Gla-300) or First- Generation Basal Insulins (BIs) in People with Type 2 Diabetes (T2D) on Once-Weekly Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RAs): Deliver New-G
- Author
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Umpierrez, G, Bailey, T, Mahieu, A, Li, X, Mabunay, M.A., and Fonseca, V
- Published
- 2024
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29. POSC81 Cost-Effectiveness Analysis of Once-Daily Insulin Glargine 300 U/mL (Gla-300) vs Insulin Degludec (IDeg-100) Using the BRAVO Diabetes Model
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Shao, H, primary, Shi, L, additional, Fonseca, V, additional, Omar Alsaleh, AJ, additional, Gill, J, additional, and Nicholls, C, additional
- Published
- 2022
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30. 359 - Ethnic disparities of vascular complications in patients with and without diabetes diagnoses
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Yoshida, Y, Zu, Y, and Fonseca, V
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- 2024
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31. Ball exercises in elderly cancer patients’ improvements
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Fonseca, V., primary, Caeiro, J., additional, Santos, A., additional, and Sarmento, P., additional
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- 2021
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32. An Overview of Geriatric Oncology in Global Clinical Practice: a SIOG National Representatives’ Survey
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Mizutani, T., primary, Cheung, K.L., additional, Hakobyan, Y., additional, Lane, H., additional, Decoster, L., additional, Karnakis, T., additional, Puts, M., additional, Calderon, O., additional, Jørgensen, T.L., additional, Boulahssass, R., additional, Wedding, U., additional, Karampeazis, T., additional, Banerjee, J., additional, Falci, C., additional, van Leeuwen, B., additional, Fonseca, V., additional, Gironés Sarrió, R., additional, Dougoud, V., additional, Naeim, A., additional, Shahrokni, A., additional, and Kanesvaran, R., additional
- Published
- 2021
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33. 641 - Risk of diabetic retinopathy in women with normal and early age menopause in the atherosclerosis risk in communities (ARIC) study
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Gandhi, P, Chen, Z, Yoshida, Y, and Fonseca, V
- Published
- 2023
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34. Treatment of Osteochondral Lesion of the First Metatarsal Head: Osteochondral Graft Transplantation Combined With Moberg Osteotomy: Case Report.
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Bruno, Machado A., Marcos, Rassi F., Wagner, Fonseca V., and Wagner, Filho V.
- Abstract
Most osteochondral lesions of the first metatarsal head are likely traumatic in etiology. The treatment ranges from microfractures to mosaicplasty. In this case report, we describe a central osteochondral lesion of the first metatarsal head treated with osteochondral graft obtained from the head of the same metatarsal in combination with Moberg osteotomy. After surgical treatment, the patient's American Orthopedic Foot and Ankle Society Forefoot Scale score improved from 58 to 85, and the range of motion also improved. This technique may be an alternative treatment modality for osteochondral lesions of the first metatarsal. Level of Evidence : Level V [ABSTRACT FROM AUTHOR]
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- 2021
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35. SIOG2021-0178 - Ball exercises in elderly cancer patients’ improvements
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Fonseca, V., Caeiro, J., Santos, A., and Sarmento, P.
- Published
- 2021
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- View/download PDF
36. SIOG2021-0041* - An Overview of Geriatric Oncology in Global Clinical Practice: a SIOG National Representatives’ Survey
- Author
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Mizutani, T., Cheung, K.L., Hakobyan, Y., Lane, H., Decoster, L., Karnakis, T., Puts, M., Calderon, O., Jørgensen, T.L., Boulahssass, R., Wedding, U., Karampeazis, T., Banerjee, J., Falci, C., van Leeuwen, B., Fonseca, V., Gironés Sarrió, R., Dougoud, V., Naeim, A., Shahrokni, A., and Kanesvaran, R.
- Published
- 2021
- Full Text
- View/download PDF
37. EE481 Long-Term Cost-Effectiveness of Tirzepatide Versus Placebo for Individuals With Type 2 Diabetes and Obesity.
- Author
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Tang, M, Guan, D, Winberg, D, Shi, L, Shao, H, and Fonseca, V
- Published
- 2024
- Full Text
- View/download PDF
38. Surgeons' perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts: results from an international survey
- Author
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Cobianchi, Lorenzo, Piccolo, Daniele, Dal Mas, Francesca, Agnoletti, Vanni, Ansaloni, Luca, Balch, Jeremy, Biffl, Walter, Butturini, Giovanni, Catena, Fausto, Coccolini, Federico, Denicolai, Stefano, De Simone, Belinda, Frigerio, Isabella, Fugazzola, Paola, Marseglia, Gianluigi, Marseglia, Giuseppe Roberto, Martellucci, Jacopo, Modenese, Mirko, Previtali, Pietro, Ruta, Federico, Venturi, Alessandro, Kaafarani, Haytham M, Loftus, Tyler J, Kenneth Lyle Abbott, Abubaker Abdelmalik, Nebyou Seyoum Abebe, Fikri Abu-Zidan, Yousif Abdallah Yousif Adam, Harissou Adamou, Dmitry Mikhailovich Adamovich, Ferdinando Agresta, Antonino Agrusa, Emrah Akin, Mario Alessiani, Henrique Alexandrino, Syed Muhammad Ali, Vasilescu Alin Mihai, Pedro Miguel Almeida, Mohammed Mohammed Al-Shehari, Michele Altomare, Francesco Amico, Michele Ammendola, Jacopo Andreuccetti, Elissavet Anestiadou, Peter Angelos, Alfredo Annicchiarico, Amedeo Antonelli, Daniel Aparicio-Sanchez, Antonella Ardito, Giulio Argenio, Catherine Claude Arvieux, Ingolf Harald Askevold, Boyko Tchavdarov Atanasov, Goran Augustin, Selmy Sabry Awad, Giulia Bacchiocchi, Carlo Bagnoli, Hany Bahouth, Efstratia Baili, Lovenish Bains, Gian Luca Baiocchi, Miklosh Bala, Carmen Balagué, Dimitrios Balalis, Edoardo Baldini, Oussama Baraket, Suman Baral, Mirko Barone, Alberto Gonzãlez Barranquero, Jorge Arturo Barreras, Gary Alan Bass, Zulfu Bayhan, Giovanni Bellanova, Offir Ben-Ishay, Fabrizio Bert, Valentina Bianchi, Helena Biancuzzi, Chiara Bidoli, Raluca Bievel Radulescu, Mark Brian Bignell, Alan Biloslavo, Daniele Bissacco, Roberto Bini, Paolo Boati, Guillaume Boddaert, Branko Bogdanic, Cristina Bombardini, Luigi Bonavina, Luca Bonomo, Andrea Bottari, Konstantinos Bouliaris, Gioia Brachini, Antonio Brillantino, Giuseppe Brisinda, Maloni Mamada Bulanauca, Luis Antonio Buonomo, Jakob Burcharth, Salvatore Buscemi, Francesca Calabretto, Giacomo Calini, Valentin Calu, Fabio Cesare Campanile, Riccardo Campo Dall Orto, Andrea Campos-Serra, Stefano Campostrini, Recayi Capoglu, Joao Miguel Carvas, Marco Cascella, Gianmaria Casoni Pattacini, Valerio Celentano, Danilo Corrado Centonze, Marco Ceresoli, Dimitrios Chatzipetris, Antonella Chessa, Maria Michela Chiarello, Mircea Chirica, Serge Chooklin, Christos Chouliaras, Sharfuddin Chowdhury, Pasquale Cianci, Nicola Cillara, Stefania Cimbanassi, Stefano Piero Bernardo Cioffi, Elif Colak, Enrique Colás Ruiz, Luigi Conti, Alessandro Coppola, Tiago Correia De Sa, Silvia Dantas Costa, Valerio Cozza, Giuseppe Curro', Kirsten Felicia Ann-Sophie Aimee Dabekaussen, Fabrizio D'Acapito, Dimitrios Damaskos, Giancarlo D'Ambrosio, Koray Das, Richard Justin Davies, Andrew Charles De Beaux, Sara Patricia De Lebrusant Fernandez, Alessandro De Luca, Francesca De Stefano, Luca Degrate, Zaza Demetrashvili, Andreas Kyriacou Demetriades, Dzemail Smail Detanac, Agnese Dezi, Giuseppe Di Buono, Isidoro Di Carlo, Pierpaolo Di Lascio, Marcello Di Martino, Salomone Di Saverio, Bogdan Diaconescu, Jose J Diaz, Rigers Dibra, Evgeni Nikolaev Dimitrov, Vincenza Paola Dinuzzi, Sandra Dios-Barbeito, Jehangir Farman Ali Diyani, Agron Dogjani, Maurizio Domanin, Mario D'Oria, Virginia Duran Munoz-Cruzado, Barbora East, Mikael Ekelund, Gerald Takem Ekwen, Adel Hamed Elbaih, Muhammed Elhadi, Natalie Enninghorst, Mairam Ernisova, Juan Pablo Escalera-Antezana, Sofia Esposito, Giuseppe Esposito, Mercedes Estaire, Camilla Nikita Farè, Roser Farre, Francesco Favi, Luca Ferrario, Antonjacopo Ferrario di Tor Vajana, Claudia Filisetti, Francesco Fleres, Vinicius Cordeiro Fonseca, Alexander Forero-Torres, Francesco Forfori, Laura Fortuna, Evangelos Fradelos, Gustavo P Fraga, Pietro Fransvea, Simone Frassini, Giuseppe Frazzetta, Erica Pizzocaro, Maximos Frountzas, Mahir Gachabayov, Rita Galeiras, Alain A Garcia Vazquez, Simone Gargarella, Ibrahim Umar Garzali, Wagih Mommtaz Ghannam, Faiz Najmuddin Ghazi, Lawrence Marshall Gillman, Rossella Gioco, Alessio Giordano, Luca Giordano, Carlo Giove, Giorgio Giraudo, Mario Giuffrida, Michela Giulii Capponi, Emanuel Gois Jr, Carlos Augusto Gomes, Felipe Couto Gomes, Ricardo Alessandro Teixeira Gonsaga, Emre Gonullu, Jacques Goosen, Tatjana Goranovic, Raquel Gracia-Roman, Giorgio Maria Paolo Graziano, Ewen Alexander Griffiths, Tommaso Guagni, Dimitar Bozhidarov Hadzhiev, Muad Gamil Haidar, Hytham K S Hamid, Timothy Craig Hardcastle, Firdaus Hayati, Andrew James Healey, Andreas Hecker, Matthias Hecker, Edgar Fernando Hernandez Garcia, Adrien Montcho Hodonou, Eduardo Cancio Huaman, Martin Huerta, Aini Fahriza Ibrahim, Basil Mohamed Salabeldin Ibrahim, Giuseppe Ietto, Marco Inama, Orestis Ioannidis, Arda Isik, Nizar Ismail, Azzain Mahadi Hamid Ismail, Ruhi Fadzlyana Jailani, Ji Young Jang, Christos Kalfountzos, Sujala Niatarika Rajsain Kalipershad, Emmanouil Kaouras, Lewis Jay Kaplan, Yasin Kara, Evika Karamagioli, Aleksandar Karamarkovia, Ioannis Katsaros, Alfie J Kavalakat, Aristotelis Kechagias, Jakub Kenig, Boris Juli Kessel, Jim S Khan, Vladimir Khokha, Jae Il Kim, Andrew Wallace Kirkpatrick, Roberto Klappenbach, Yoram Kluger, Yoshiro Kobe, Efstratios Kofopoulos Lymperis, Kenneth Yuh Yen Kok, Victor Kong, Dimitris P Korkolis, Georgios Koukoulis, Bojan Kovacevic, Vitor Favali Kruger, Igor A Kryvoruchko, Hayato Kurihara, Akira Kuriyama, Aitor Landaluce-Olavarria, Pierfrancesco Lapolla, Ari Leppäniemi, Leo Licari, Giorgio Lisi, Andrey Litvin, Aintzane Lizarazu, Heura Llaquet Bayo, Varut Lohsiriwat, Claudia Cristina Lopes Moreira, Eftychios Lostoridis, Agustãn Tovar Luna, Davide Luppi, Gustavo Miguel Machain V, Marc Maegele, Daniele Maggiore, Stefano Magnone, Ronald V Maier, Piotr Major, Mallikarjuna Manangi, Andrea Manetti, Baris Mantoglu, Chiara Marafante, Federico Mariani, Athanasios Marinis, Evandro Antonio Sbalcheiro Mariot, Gennaro Martines, Aleix Martinez Perez, Costanza Martino, Pietro Mascagni, Damien Massalou, Maurizio Massaro, Belen Matías-García, Gennaro Mazzarella, Giorgio Mazzarolo, Renato Bessa Melo, Fernando Mendoza-Moreno, Serhat Meric, Jeremy Meyer, Luca Miceli, Nikolaos V Michalopoulos, Flavio Milana, Andrea Mingoli, Tushar S Mishra, Muyed Mohamed, Musab Isam Eldin Abbas Mohamed, Ali Yasen Mohamedahmed, Mohammed Jibreel Suliman Mohammed, Rajashekar Mohan, Ernest E Moore, Dieter Morales-Garcia, Mã Ns Muhrbeck, Francesk Mulita, Sami Mohamed Siddig Mustafa, Edoardo Maria Muttillo, Mukhammad David Naimzada, Pradeep H Navsaria, Ionut Negoi, Luca Nespoli, Christine Nguyen, Melkamu Kibret Nidaw, Giuseppe Nigri, Ioannis Nikolopoulos, Donal Brendan O'Connor, Habeeb Damilola Ogundipe, Cristina Oliveri, Stefano Olmi, Ernest Cun Wang Ong, Luca Orecchia, Aleksei V Osipov, Muhammad Faeid Othman, Marco Pace, Mario Pacilli, Leonardo Pagani, Giuseppe Palomba, Desire' Pantalone, Arpad Panyko, Ciro Paolillo, Mario Virgilio Papa, Dimitrios Papaconstantinou, Maria Papadoliopoulou, Aristeidis Papadopoulos, Davide Papis, Nikolaos Pararas, Jose Gustavo Parreira, Neil Geordie Parry, Francesco Pata, Tapan Patel, Simon Paterson-Brown, Giovanna Pavone, Francesca Pecchini, Veronica Pegoraro, Gianluca Pellino, Maria Pelloni, Andrea Peloso, Eduardo Perea Del Pozo, Rita Goncalves Pereira, Bruno Monteiro Pereira, Aintzane Lizarazu Perez, Silvia Pérez, Teresa Perra, Gennaro Perrone, Antonio Pesce, Lorenzo Petagna, Giovanni Petracca, Vorapong Phupong, Biagio Picardi, Arcangelo Picciariello, Micaela Piccoli, Edoardo Picetti, Emmanouil Pikoulis Pikoulis, Tadeja Pintar, Giovanni Pirozzolo, Francesco Piscioneri, Mauro Podda, Alberto Porcu, Francesca Privitera, Clelia Punzo, Silvia Quaresima, Martha Alexa Quiodettis, Niels Qvist, Razrim Rahim, Filipe Ramalho de Almeida, Rosnelifaizur Bin Ramely, Huseyin Kemal Rasa, Martin Reichert, Alexander Reinisch-Liese, Angela Renne, Camilla Riccetti, Maria Rita Rodriguez-Luna, Daniel Roizblatt, Andrea Romanzi, Luigi Romeo, Francesco Pietro Maria Roscio, Ramely Bin Rosnelifaizur, Stefano Rossi, Andres M Rubiano, Elena Ruiz-Ucar, Boris Evgeniev Sakakushev, Juan Carlos Salamea, Ibrahima Sall, Lasitha Bhagya Samarakoon, Fabrizio Sammartano, Alejandro Sanchez Arteaga, Sergi Sanchez-Cordero, Domenico Pietro Maria Santoanastaso, Massimo Sartelli, Diego Sasia, Norio Sato, Artem Savchuk, Robert Grant Sawyer, Giacomo Scaioli, Dimitrios Schizas, Simone Sebastiani, Barbara Seeliger, Helmut Alfredo Segovia Lohse, Charalampos Seretis, Giacomo Sermonesi, Mario Serradilla-Martin, Vishal G Shelat, Sergei Shlyapnikov, Theodoros Sidiropoulos, Romeo Lages Simoes, Leandro Siragusa, Boonying Siribumrungwong, Mihail Slavchev, Leonardo Solaini, Gabriele Soldini, Andrey Sopuev, Kjetil Soreide, Apostolos Sovatzidis, Philip Frank Stahel, Matt Strickland, Mohamed Arif Hameed Sultan, Ruslan Sydorchuk, Larysa Sydorchuk, Syed Muhammad Ali Muhammad Syed, Luis Tallon-Aguilar, Andrea Marco Tamburini, Nicolò Tamini, Edward C T H Tan, Jih Huei Tan, Antonio Tarasconi, Nicola Tartaglia, Giuseppe Tartaglia, Dario Tartaglia, John Vincent Taylor, Giovanni Domenico Tebala, Michel Teuben, Alexis Theodorou, Matti Tolonen, Giovanni Tomasicchio, Adriana Toro, Beatrice Torre, Tania Triantafyllou, Giuseppe Trigiante Trigiante, Marzia Tripepi, Julio Trostchansky, Konstantinos Tsekouras, Victor Turrado-Rodriguez, Roberta Tutino, Matteo Uccelli, Petar Angelov Uchikov, Bakarne Ugarte-Sierra, Mika Tapani Ukkonen, Michail Vailas, Panteleimon G Vassiliu, Alain Garcia Vazquez, Rita Galeiras Vazquez, George Velmahos, Juan Ezequiel Verde, Juan Manuel Verde, Massimiliano Veroux, Jacopo Viganò, Ramon Vilallonga, Diego Visconti, Alessandro Vittori, Maciej Waledziak, Tongporn Wannatoop, Lukas Werner Widmer, Michael Samuel James Wilson, Sarah Woltz, Ting Hway Wong, Sofia Xenaki, Byungchul Yu, Steven Yule, Sanoop Koshy Zachariah, Georgios Zacharis, Claudia Zaghi, Andee Dzulkarnaen Zakaria, Diego A Zambrano, Nikolaos Zampitis, Biagio Zampogna, Simone Zanghì, Maristella Zantedeschi, Konstantinos Zapsalis, Fabio Zattoni, Monica Zese, Lorenzo, Cobianchi, Daniele, Piccolo, Francesca, Dal Ma, Vanni, Agnoletti, Luca, Ansaloni, Jeremy, Balch, Walter, Biffl, Giovanni, Butturini, Fausto, Catena, Federico, Coccolini, Stefano, Denicolai, Belinda, De Simone, Isabella, Frigerio, Paola, Fugazzola, Gianluigi, Marseglia, Giuseppe Roberto, Marseglia, Jacopo, Martellucci, Mirko, Modenese, Pietro, Previtali, Federico, Ruta, Alessandro, Venturi, Haytham M, Kaafarani, Tyler J, Loftu, Lyle Abbott, Kenneth, Abdelmalik, Abubaker, Seyoum Abebe, Nebyou, Abu-Zidan, Fikri, Abdallah Yousif Adam, Yousif, Adamou, Harissou, Mikhailovich Adamovich, Dmitry, Agresta, Ferdinando, Agrusa, Antonino, Akin, Emrah, Alessiani, Mario, Alexandrino, Henrique, Muhammad Ali, Syed, Alin Mihai, Vasilescu, Miguel Almeida, Pedro, Mohammed Al-Shehari, Mohammed, Altomare, Michele, Amico, Francesco, Ammendola, Michele, Andreuccetti, Jacopo, Anestiadou, Elissavet, Angelos, Peter, Annicchiarico, Alfredo, Antonelli, Amedeo, Aparicio-Sanchez, Daniel, Ardito, Antonella, Argenio, Giulio, Claude Arvieux, Catherine, Harald Askevold, Ingolf, Tchavdarov Atanasov, Boyko, Augustin, Goran, Sabry Awad, Selmy, Bacchiocchi, Giulia, Bagnoli, Carlo, Bahouth, Hany, Baili, Efstratia, Bains, Lovenish, Luca Baiocchi, Gian, Bala, Miklosh, Balagué, Carmen, Balalis, Dimitrio, Baldini, Edoardo, Baraket, Oussama, Baral, Suman, Barone, Mirko, Gonzãlez Barranquero, Alberto, Arturo Barreras, Jorge, Alan Bass, Gary, Bayhan, Zulfu, Bellanova, Giovanni, Ben-Ishay, Offir, Bert, Fabrizio, Bianchi, Valentina, Biancuzzi, Helena, Bidoli, Chiara, Bievel Radulescu, Raluca, Brian Bignell, Mark, Biloslavo, Alan, Bissacco, Daniele, Bini, Roberto, Boati, Paolo, Boddaert, Guillaume, Bogdanic, Branko, Bombardini, Cristina, Bonavina, Luigi, Bonomo, Luca, Bottari, Andrea, Bouliaris, Konstantino, Brachini, Gioia, Brillantino, Antonio, Brisinda, Giuseppe, Mamada Bulanauca, Maloni, Antonio Buonomo, Lui, Burcharth, Jakob, Buscemi, Salvatore, Calabretto, Francesca, Calini, Giacomo, Calu, Valentin, Cesare Campanile, Fabio, Campo Dall Orto, Riccardo, Campos-Serra, Andrea, Campostrini, Stefano, Capoglu, Recayi, Miguel Carvas, Joao, Cascella, Marco, Casoni Pattacini, Gianmaria, Celentano, Valerio, Corrado Centonze, Danilo, Ceresoli, Marco, Chatzipetris, Dimitrio, Chessa, Antonella, Michela Chiarello, Maria, Chirica, Mircea, Chooklin, Serge, Chouliaras, Christo, Chowdhury, Sharfuddin, Cianci, Pasquale, Cillara, Nicola, Cimbanassi, Stefania, Piero Bernardo Cioffi, Stefano, Colak, Elif, Colás Ruiz, Enrique, Conti, Luigi, Coppola, Alessandro, Correia De Sa, Tiago, Dantas Costa, Silvia, Cozza, Valerio, Curro', Giuseppe, Felicia Ann-Sophie Aimee Dabekaussen, Kirsten, D'Acapito, Fabrizio, Damaskos, Dimitrio, D'Ambrosio, Giancarlo, Das, Koray, Justin Davies, Richard, Charles De Beaux, Andrew, Patricia De Lebrusant Fernandez, Sara, De Luca, Alessandro, De Stefano, Francesca, Degrate, Luca, Demetrashvili, Zaza, Kyriacou Demetriades, Andrea, Smail Detanac, Dzemail, Dezi, Agnese, Di Buono, Giuseppe, Di Carlo, Isidoro, Di Lascio, Pierpaolo, Di Martino, Marcello, Di Saverio, Salomone, Diaconescu, Bogdan, J Diaz, Jose, Dibra, Riger, Nikolaev Dimitrov, Evgeni, Paola Dinuzzi, Vincenza, Dios-Barbeito, Sandra, Farman Ali Diyani, Jehangir, Dogjani, Agron, Domanin, Maurizio, D'Oria, Mario, Duran Munoz-Cruzado, Virginia, East, Barbora, Ekelund, Mikael, Takem Ekwen, Gerald, Hamed Elbaih, Adel, Elhadi, Muhammed, Enninghorst, Natalie, Ernisova, Mairam, Pablo Escalera-Antezana, Juan, Esposito, Sofia, Esposito, Giuseppe, Estaire, Mercede, Nikita Farè, Camilla, Farre, Roser, Favi, Francesco, Ferrario, Luca, Ferrario di Tor Vajana, Antonjacopo, Filisetti, Claudia, Fleres, Francesco, Cordeiro Fonseca, Viniciu, Forero-Torres, Alexander, Forfori, Francesco, Fortuna, Laura, Fradelos, Evangelo, P Fraga, Gustavo, Fransvea, Pietro, Frassini, Simone, Frazzetta, Giuseppe, Pizzocaro, Erica, Frountzas, Maximo, Gachabayov, Mahir, Galeiras, Rita, A Garcia Vazquez, Alain, Gargarella, Simone, Umar Garzali, Ibrahim, Mommtaz Ghannam, Wagih, Najmuddin Ghazi, Faiz, Marshall Gillman, Lawrence, Gioco, Rossella, Giordano, Alessio, Giordano, Luca, Giove, Carlo, Giraudo, Giorgio, Giuffrida, Mario, Giulii Capponi, Michela, Gois Jr, Emanuel, Augusto Gomes, Carlo, Couto Gomes, Felipe, Alessandro Teixeira Gonsaga, Ricardo, Gonullu, Emre, Goosen, Jacque, Goranovic, Tatjana, Gracia-Roman, Raquel, Maria Paolo Graziano, Giorgio, Alexander Griffiths, Ewen, Guagni, Tommaso, Bozhidarov Hadzhiev, Dimitar, Gamil Haidar, Muad, S Hamid, Hytham K, Craig Hardcastle, Timothy, Hayati, Firdau, James Healey, Andrew, Hecker, Andrea, Hecker, Matthia, Fernando Hernandez Garcia, Edgar, Montcho Hodonou, Adrien, Cancio Huaman, Eduardo, Huerta, Martin, Fahriza Ibrahim, Aini, Mohamed Salabeldin Ibrahim, Basil, Ietto, Giuseppe, Inama, Marco, Ioannidis, Oresti, Isik, Arda, Ismail, Nizar, Mahadi Hamid Ismail, Azzain, Fadzlyana Jailani, Ruhi, Young Jang, Ji, Kalfountzos, Christo, Niatarika Rajsain Kalipershad, Sujala, Kaouras, Emmanouil, Jay Kaplan, Lewi, Kara, Yasin, Karamagioli, Evika, Karamarkovia, Aleksandar, Katsaros, Ioanni, J Kavalakat, Alfie, Kechagias, Aristoteli, Kenig, Jakub, Juli Kessel, Bori, S Khan, Jim, Khokha, Vladimir, Il Kim, Jae, Wallace Kirkpatrick, Andrew, Klappenbach, Roberto, Kluger, Yoram, Kobe, Yoshiro, Kofopoulos Lymperis, Efstratio, Yuh Yen Kok, Kenneth, Kong, Victor, P Korkolis, Dimitri, Koukoulis, Georgio, Kovacevic, Bojan, Favali Kruger, Vitor, A Kryvoruchko, Igor, Kurihara, Hayato, Kuriyama, Akira, Landaluce-Olavarria, Aitor, Lapolla, Pierfrancesco, Leppäniemi, Ari, Licari, Leo, Lisi, Giorgio, Litvin, Andrey, Lizarazu, Aintzane, Llaquet Bayo, Heura, Lohsiriwat, Varut, Cristina Lopes Moreira, Claudia, Lostoridis, Eftychio, Tovar Luna, Agustãn, Luppi, Davide, V, Gustavo Miguel Machain, Maegele, Marc, Maggiore, Daniele, Magnone, Stefano, V Maier, Ronald, Major, Piotr, Manangi, Mallikarjuna, Manetti, Andrea, Mantoglu, Bari, Marafante, Chiara, Mariani, Federico, Marinis, Athanasio, Antonio Sbalcheiro Mariot, Evandro, Martines, Gennaro, Martinez Perez, Aleix, Martino, Costanza, Mascagni, Pietro, Massalou, Damien, Massaro, Maurizio, Matías-García, Belen, Mazzarella, Gennaro, Mazzarolo, Giorgio, Bessa Melo, Renato, Mendoza-Moreno, Fernando, Meric, Serhat, Meyer, Jeremy, Miceli, Luca, V Michalopoulos, Nikolao, Milana, Flavio, Mingoli, Andrea, S Mishra, Tushar, Mohamed, Muyed, Isam Eldin Abbas Mohamed, Musab, Yasen Mohamedahmed, Ali, Jibreel Suliman Mohammed, Mohammed, Mohan, Rajashekar, E Moore, Ernest, Morales-Garcia, Dieter, Ns Muhrbeck, Mã, Mulita, Francesk, Mohamed Siddig Mustafa, Sami, Maria Muttillo, Edoardo, David Naimzada, Mukhammad, H Navsaria, Pradeep, Negoi, Ionut, Nespoli, Luca, Nguyen, Christine, Kibret Nidaw, Melkamu, Nigri, Giuseppe, Nikolopoulos, Ioanni, Brendan O'Connor, Donal, Damilola Ogundipe, Habeeb, Oliveri, Cristina, Olmi, Stefano, Cun Wang Ong, Ernest, Orecchia, Luca, V Osipov, Aleksei, Faeid Othman, Muhammad, Pace, Marco, Pacilli, Mario, Pagani, Leonardo, Palomba, Giuseppe, Pantalone, Desire', Panyko, Arpad, Paolillo, Ciro, Virgilio Papa, Mario, Papaconstantinou, Dimitrio, Papadoliopoulou, Maria, Papadopoulos, Aristeidi, Papis, Davide, Pararas, Nikolao, Gustavo Parreira, Jose, Geordie Parry, Neil, Pata, Francesco, Patel, Tapan, Paterson-Brown, Simon, Pavone, Giovanna, Pecchini, Francesca, Pegoraro, Veronica, Pellino, Gianluca, Pelloni, Maria, Peloso, Andrea, Perea Del Pozo, Eduardo, Goncalves Pereira, Rita, Monteiro Pereira, Bruno, Lizarazu Perez, Aintzane, Pérez, Silvia, Perra, Teresa, Perrone, Gennaro, Pesce, Antonio, Petagna, Lorenzo, Petracca, Giovanni, Phupong, Vorapong, Picardi, Biagio, Picciariello, Arcangelo, Piccoli, Micaela, Picetti, Edoardo, Pikoulis Pikoulis, Emmanouil, Pintar, Tadeja, Pirozzolo, Giovanni, Piscioneri, Francesco, Podda, Mauro, Porcu, Alberto, Privitera, Francesca, Punzo, Clelia, Quaresima, Silvia, Alexa Quiodettis, Martha, Qvist, Niel, Rahim, Razrim, Ramalho de Almeida, Filipe, Bin Ramely, Rosnelifaizur, Kemal Rasa, Huseyin, Reichert, Martin, Reinisch-Liese, Alexander, Renne, Angela, Riccetti, Camilla, Rita Rodriguez-Luna, Maria, Roizblatt, Daniel, Romanzi, Andrea, Romeo, Luigi, Pietro Maria Roscio, Francesco, Bin Rosnelifaizur, Ramely, Rossi, Stefano, M Rubiano, Andre, Ruiz-Ucar, Elena, Evgeniev Sakakushev, Bori, Carlos Salamea, Juan, Sall, Ibrahima, Bhagya Samarakoon, Lasitha, Sammartano, Fabrizio, Sanchez Arteaga, Alejandro, Sanchez-Cordero, Sergi, Pietro Maria Santoanastaso, Domenico, Sartelli, Massimo, Sasia, Diego, Sato, Norio, Savchuk, Artem, Grant Sawyer, Robert, Scaioli, Giacomo, Schizas, Dimitrio, Sebastiani, Simone, Seeliger, Barbara, Alfredo Segovia Lohse, Helmut, Seretis, Charalampo, Sermonesi, Giacomo, Serradilla-Martin, Mario, G Shelat, Vishal, Shlyapnikov, Sergei, Sidiropoulos, Theodoro, Lages Simoes, Romeo, Siragusa, Leandro, Siribumrungwong, Boonying, Slavchev, Mihail, Solaini, Leonardo, Soldini, Gabriele, Sopuev, Andrey, Soreide, Kjetil, Sovatzidis, Apostolo, Frank Stahel, Philip, Strickland, Matt, Arif Hameed Sultan, Mohamed, Sydorchuk, Ruslan, Sydorchuk, Larysa, Muhammad Ali Muhammad Syed, Syed, Tallon-Aguilar, Lui, Marco Tamburini, Andrea, Tamini, Nicolò, H Tan, Edward C T, Huei Tan, Jih, Tarasconi, Antonio, Tartaglia, Nicola, Tartaglia, Giuseppe, Tartaglia, Dario, Vincent Taylor, John, Domenico Tebala, Giovanni, Teuben, Michel, Theodorou, Alexi, Tolonen, Matti, Tomasicchio, Giovanni, Toro, Adriana, Torre, Beatrice, Triantafyllou, Tania, Trigiante Trigiante, Giuseppe, Tripepi, Marzia, Trostchansky, Julio, Tsekouras, Konstantino, Turrado-Rodriguez, Victor, Tutino, Roberta, Uccelli, Matteo, Angelov Uchikov, Petar, Ugarte-Sierra, Bakarne, Tapani Ukkonen, Mika, Vailas, Michail, G Vassiliu, Panteleimon, Garcia Vazquez, Alain, Galeiras Vazquez, Rita, Velmahos, George, Ezequiel Verde, Juan, Manuel Verde, Juan, Veroux, Massimiliano, Viganò, Jacopo, Vilallonga, Ramon, Visconti, Diego, Vittori, Alessandro, Waledziak, Maciej, Wannatoop, Tongporn, Werner Widmer, Luka, Samuel James Wilson, Michael, Woltz, Sarah, Hway Wong, Ting, Xenaki, Sofia, Yu, Byungchul, Yule, Steven, Koshy Zachariah, Sanoop, Zacharis, Georgio, Zaghi, Claudia, Dzulkarnaen Zakaria, Andee, A Zambrano, Diego, Zampitis, Nikolao, Zampogna, Biagio, Zanghì, Simone, Zantedeschi, Maristella, Zapsalis, Konstantino, Zattoni, Fabio, Zese, Monica, Cobianchi L., Piccolo D., Mas F.D., Agnoletti V., Ansaloni L., Balch J., Biffl W., Butturini G., Catena F., Coccolini F., Denicolai S., De Simone B., Frigerio I., Fugazzola P., Marseglia G., Marseglia G.R., Martellucci J., Modenese M., Previtali P., Ruta F., Venturi A., Kaafarani H.M., Loftus T.J., Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Team Dynamics Study Group, Cobianchi, L, Piccolo, D, Dal Mas, F, Agnoletti, V, Ansaloni, L, Balch, J, Biffl, W, Butturini, G, Catena, F, Coccolini, F, Denicolai, S, De Simone, B, Frigerio, I, Fugazzola, P, Marseglia, G, Martellucci, J, Modenese, M, Previtali, P, Ruta, F, Venturi, A, Kaafarani, H, Loftus, T, Abbott, K, Abdelmalik, A, Abebe, N, Abu-Zidan, F, Adam, Y, Adamou, H, Adamovich, D, Agresta, F, Agrusa, A, Akin, E, Alessiani, M, Alexandrino, H, Ali, S, Mihai, V, Almeida, P, Al-Shehari, M, Altomare, M, Amico, F, Ammendola, M, Andreuccetti, J, Anestiadou, E, Angelos, P, Annicchiarico, A, Antonelli, A, Aparicio-Sanchez, D, Ardito, A, Argenio, G, Arvieux, C, Askevold, I, Atanasov, B, Augustin, G, Awad, S, Bacchiocchi, G, Bagnoli, C, Bahouth, H, Baili, E, Bains, L, Baiocchi, G, Bala, M, Balague, C, Balalis, D, Baldini, E, Baraket, O, Baral, S, Barone, M, Barranquero, A, Barreras, J, Bass, G, Bayhan, Z, Bellanova, G, Ben-Ishay, O, Bert, F, Bianchi, V, Biancuzzi, H, Bidoli, C, Radulescu, R, Bignell, M, Biloslavo, A, Bini, R, Bissacco, D, Boati, P, Boddaert, G, Bogdanic, B, Bombardini, C, Bonavina, L, Bonomo, L, Bottari, A, Bouliaris, K, Brachini, G, Brillantino, A, Brisinda, G, Bulanauca, M, Buonomo, L, Burcharth, J, Buscemi, S, Calabretto, F, Calini, G, Calu, V, Campanile, F, Dall'Orto, R, Campos-Serra, A, Campostrini, S, Capoglu, R, Carvas, J, Cascella, M, Pattacini, G, Celentano, V, Centonze, D, Ceresoli, M, Chatzipetris, D, Chessa, A, Chiarello, M, Chirica, M, Chooklin, S, Chouliaras, C, Chowdhury, S, Cianci, P, Cillara, N, Cimbanassi, S, Cioffi, S, Colak, E, Ruiz, E, Conti, L, Coppola, A, De Sa, T, Costa, S, Cozza, V, Curro', G, Dabekaussen, K, D'Acapito, F, Damaskos, D, D'Ambrosio, G, Das, K, Davies, R, De Beaux, A, Fernandez, S, De Luca, A, De Stefano, F, Degrate, L, Demetrashvili, Z, Demetriades, A, Detanac, D, Dezi, A, Di Buono, G, Di Carlo, I, Di Lascio, P, Di Martino, M, Di Saverio, S, Diaconescu, B, Diaz, J, Dibra, R, Dimitrov, E, Dinuzzi, V, Dios-Barbeito, S, Diyani, J, Dogjani, A, Domanin, M, D'Oria, M, Munoz-Cruzado, V, East, B, Ekelund, M, Ekwen, G, Elbaih, A, Elhadi, M, Enninghorst, N, Ernisova, M, Escalera-Antezana, J, Esposito, S, Esposito, G, Estaire, M, Fare, C, Farre, R, Favi, F, Ferrario, L, Vajana, A, Filisetti, C, Fleres, F, Fonseca, V, Forero-Torres, A, Forfori, F, Fortuna, L, Fradelos, E, Fraga, G, Fransvea, P, Frassini, S, Frazzetta, G, Pizzocaro, E, Frountzas, M, Gachabayov, M, Galeiras, R, Vazquez, A, Gargarella, S, Garzali, I, Ghannam, W, Ghazi, F, Gillman, L, Gioco, R, Giordano, A, Giordano, L, Giove, C, Giraudo, G, Giuffrida, M, Capponi, M, Gois, E, Gomes, C, Gomes, F, Gonsaga, R, Gonullu, E, Goosen, J, Goranovic, T, Gracia-Roman, R, Graziano, G, Griffiths, E, Guagni, T, Hadzhiev, D, Haidar, M, Hamid, H, Hardcastle, T, Hayati, F, Healey, A, Hecker, A, Hecker, M, Garcia, E, Hodonou, A, Huaman, E, Huerta, M, Ibrahim, A, Ibrahim, B, Ietto, G, Inama, M, Ioannidis, O, Isik, A, Ismail, N, Ismail, A, Jailani, R, Jang, J, Kalfountzos, C, Kalipershad, S, Kaouras, E, Kaplan, L, Kara, Y, Karamagioli, E, Karamarkovia, A, Katsaros, I, Kavalakat, A, Kechagias, A, Kenig, J, Kessel, B, Khan, J, Khokha, V, Kim, J, Kirkpatrick, A, Klappenbach, R, Kluger, Y, Kobe, Y, Lymperis, E, Kok, K, Kong, V, Korkolis, D, Koukoulis, G, Kovacevic, B, Kruger, V, Kryvoruchko, I, Kurihara, H, Kuriyama, A, Landaluce-Olavarria, A, Lapolla, P, Leppaniemi, A, Licari, L, Lisi, G, Litvin, A, Lizarazu, A, Bayo, H, Lohsiriwat, V, Moreira, C, Lostoridis, E, Luna, A, Luppi, D, Machain, V, Maegele, M, Maggiore, D, Magnone, S, Maier, R, Major, P, Manangi, M, Manetti, A, Mantoglu, B, Marafante, C, Mariani, F, Marinis, A, Mariot, E, Martines, G, Perez, A, Martino, C, Mascagni, P, Massalou, D, Massaro, M, Matias-Garcia, B, Mazzarella, G, Mazzarolo, G, Melo, R, Mendoza-Moreno, F, Meric, S, Meyer, J, Miceli, L, Michalopoulos, N, Milana, F, Mingoli, A, 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Uccelli, M, Uchikov, P, Ugarte-Sierra, B, Ukkonen, M, Vailas, M, Vassiliu, P, Vazquez, R, Velmahos, G, Verde, J, Veroux, M, Vigano, J, Vilallonga, R, Visconti, D, Vittori, A, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Woltz, S, Wong, T, Xenaki, S, Yu, B, Yule, S, Zachariah, S, Zacharis, G, Zaghi, C, Zakaria, A, Zambrano, D, Zampitis, N, Zampogna, B, Zanghi, S, Zantedeschi, M, Zapsalis, K, Zattoni, F, and Zese, M
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Settore SECS-P/10 - Organizzazione Aziendale ,Settore MED/18 - Chirurgia Generale ,Artificial intelligence ,Settore SECS-P/07 - Economia Aziendale ,Decision aid ,Emergency Medicine ,Decision aids ,Surgery ,[SDV.IB]Life Sciences [q-bio]/Bioengineering ,Trauma and emergency surgery ,Clinical decision-making ,Survey - Abstract
Background Artificial intelligence (AI) is gaining traction in medicine and surgery. AI-based applications can offer tools to examine high-volume data to inform predictive analytics that supports complex decision-making processes. Time-sensitive trauma and emergency contexts are often challenging. The study aims to investigate trauma and emergency surgeons’ knowledge and perception of using AI-based tools in clinical decision-making processes. Methods An online survey grounded on literature regarding AI-enabled surgical decision-making aids was created by a multidisciplinary committee and endorsed by the World Society of Emergency Surgery (WSES). The survey was advertised to 917 WSES members through the society’s website and Twitter profile. Results 650 surgeons from 71 countries in five continents participated in the survey. Results depict the presence of technology enthusiasts and skeptics and surgeons' preference toward more classical decision-making aids like clinical guidelines, traditional training, and the support of their multidisciplinary colleagues. A lack of knowledge about several AI-related aspects emerges and is associated with mistrust. Discussion The trauma and emergency surgical community is divided into those who firmly believe in the potential of AI and those who do not understand or trust AI-enabled surgical decision-making aids. Academic societies and surgical training programs should promote a foundational, working knowledge of clinical AI.
- Published
- 2023
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39. Time for a paradigm shift in shared decision-making in trauma and emergency surgery? Results from an international survey
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Cobianchi, Lorenzo, Dal Mas, Francesca, Agnoletti, Vanni, Ansaloni, Luca, Biffl, Walter, Butturini, Giovanni, Campostrini, Stefano, Catena, Fausto, Denicolai, Stefano, Fugazzola, Paola, Martellucci, Jacopo, Massaro, Maurizio, Previtali, Pietro, Ruta, Federico, Venturi, Alessandro, Woltz, Sarah, Kaafarani, Haytham M., Loftus, Tyler J., Aapoäÿlu, Recayi, Abbott, Kenneth Lyle, Abdelmalik, Abubaker, Abebe, Nebyou Seyoum, Abu-Zidan, Fikri, Adam, Yousif Abdallah Yousif, Adamou, Harissou, Adamovich, Dmitry Mikhailovich, Agresta, Ferdinando, Agrusa, Antonino, Akin, Emrah, Alessiani, Mario, Alexandrino, Henrique, Bidoli, Chiara, Ali, Syed Muhammad, Mihai, Vasilescu Alin, Almeida, Pedro Miguel, Al-Shehari, Mohammed Mohammed, Altomare, Michele, Amico, Francesco, Ammendola, Michele, Andreuccetti, Jacopo, Anestiadou, Elissavet, Annicchiarico, Alfredo, Antonelli, Amedeo, Aparicio-Sanchez, Daniel, Ardito, Antonella, Argenio, Giulio, Arvieux, Catherine Claude, Arvieux, Catherine, Askevold, Ingolf Harald, Atanasov, Boyko Tchavdarov, Augustin, Goran, Awad, Selmy Sabry, Bacchiocchi, Giulia, Bagnoli, Carlo, Bahouth, Hany, Baili, Efstratia, Bains, Lovenish, Baiocchi, Gian Luca, Bala, Miklosh, Balaguà©, Carmen, Balalis, Dimitrios, Baldini, Edoardo, Baraket, Oussama, Baral, Suman, Barone, Mirko, Gonzãlez Barranquero, Alberto, Barreras, Jorge Arturo, Bass, Gary Alan, Bayhan, Zulfu, Bellanova, Giovanni, Ben-Ishay, Offir, Bert, Fabrizio, Bianchi, Valentina, Biancuzzi, Helena, Radulescu, Raluca Bievel, Bignell, Mark Brian, Biloslavo, Alan, Bini, Roberto, Bissacco, Daniele, Boati, Paoll, Boddaert, Guillaume, Bogdanic, Branko, Bombardini, Cristina, Bonavina, Luigi, Bonomo, Luca, Bottari, Andrea, Bouliaris, Konstantinos, Brachini, Gioia, Brillantino, Antonio, Brisinda, Giuseppe, Bulanauca, Maloni Mamada, Buonomo, Luis Antonio, Burcharth, Jakob, Buscemi, Salvatore, Calabretto, Francesca, Calini, Giacomo, Calu, Valentin, Campanile, Fabio Cesare, Campo Dall’Orto, Riccardo, Campos-Serra, Andrea, Carvas, Joao Miguel, Cascella, Marco, Pattacini, Gianmaria Casoni, Celentano, Valerio, Centonze, Danilo Corrado, Ceresoli, Marco, Chatzipetris, Dimitrios, Chessa, Antonella, Chiarello, Maria Michela, Chirica, Mircea, Chooklin, Serge, Chouliaras, Christos, Chowdhury, Sharfuddin, Cianci, Pasquale, Cillara, Nicola, Cimbanassi, Stefania, Cioffi, Stefano Piero Bernardo, Colãis-Ruiz, Enrique, Colak, Elif, Conti, Luigi, Coppola, Alessandro, de Sa, Tiago Correia, Costa, Silvia Dantas, Cozza, Valerio, Curro’, Giuseppe, Dabekaussen, Kirsten Felicia Ann-Sophie Aimee, D’Acapito, Fabrizio, Damaskos, Dimitrios, D’Ambrosio, Giancarlo, Das, Koray, Davies, Richard Justin, de Beaux, Andrew Charles, De Lebrusant Fernandez, Sara Patricia, De Luca, Alessandro, De Simone, Belinda, De Stefano, Francesca, Degrate, Luca, Demetrashvili, Zaza, Demetriades, Andreas Kyriacou, Detanac, Dzemail Smail, Dezi, Agnese, Di Buono, Giuseppe, Carlo, Isidoro-D. I., Di Lascio, Pierpaolo, Di Martino, Marcello, Di Saverio, Salomone, Diaconescu, Bogdan, Diaz, Jose J., Dibra, Rigers, Dimitrov, Evgeni Nikolaev, Dinuzzi, Vincenza Paola, Dios-Barbeito, Sandra, Diyani, Jehangir Farman Ali, Dogjani, Agron, Domanin, Maurizio, D’Oria, Mario, Munoz-Cruzado, Virginia Duran, East, Barbora, Ekelund, Mikael, Ekwen, Gerald Takem, Elbaih, Adel Hamed, Elhadi, Muhammed, Enninghorst, Natalie, Ernisova, Mairam, Escalera-Antezana, Juan Pablo, Esposito, Sofia, Esposito, Giuseppe, Estaire-Gãmez, Mercedes, Farã, Camilla Nikita, Farre, Roser, Favi, Francesco, Ferrario, Luca, Ferrario di Tor Vajana, Antonjacopo, Filisetti, Claudia, Fleres, Francesco, Fonseca, Vinicius Cordeiro, Forero-Torres, Alexander, Forfori, Francesco, Fortuna, Laura, Fradelos, Evangelos, Fraga, Gustavo P., Fransvea, Pietro, Frassini, Simone, Frazzetta, Giuseppe, Frigerio, Isabella, Frountzas, Maximos, Gachabayov, Mahir, Galeiras, Rita, Garcãa, Belen Matãas, Garcia Vazquez, Alain, Gargarella, Simone, Garzali, Ibrahim Umar, Ghannam, Wagih Mommtaz, Ghazi, Faiz Najmuddin, Gillman, Lawrence Marshall, Gioco, Rossella, Giordano, Alessio, Giordano, Luca, Giove, Carlo, Giraudo, Giorgio, Giuffrida, Mario, Capponi, Michela Giulii, Gois, Emanuel, Gomes, Carlos Augusto, Gomes, Felipe Couto, Gonsaga, Ricardo Alessandro Teixeira, Gonullu, Emre, Goosen, Jacques, Goranovic, Tatjana, Gracia-Roman, Raquel, Graziano, Giorgio Maria Paolo, Griffiths, Ewen Alexander, Guagni, Tommaso, Hadzhiev, Dimitar Bozhidarov, Haidar, Muad Gamil, Hamid, Hytham K. 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T. 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Quiodettis, M, Qvist, N, Rahim, R, de Almeida, F, Ramely, R, Rasa, H, Reichert, M, Reinisch-Liese, A, Renne, A, Riccetti, C, Rodriguez-Luna, M, Roizblatt, D, Romanzi, A, Romeo, L, Roscio, F, Rosnelifaizur, R, Rossi, S, Rubiano, A, Ruiz-Ascar, E, Sakakushev, B, Salamea, J, Sall, I, Samarakoon, L, Sammartano, F, Arteaga, A, Sanchez-Cordero, S, Santoanastaso, D, Sasia, D, Sato, N, Savchuk, A, Sawyer, R, Scaioli, G, Schizas, D, Sebastiani, S, Seeliger, B, Lohse, H, Seretis, C, Sermonesi, G, Serradilla-Martin, M, Shelat, V, Shlyapnikov, S, Sidiropoulos, T, Simoes, R, Siragusa, L, Siribumrungwong, B, Slavchev, M, Solaini, L, Soldini, G, Sopuev, A, Soreide, K, Sovatzidis, A, Stahel, P, Strickland, M, Sultan, M, Sydorchuk, R, Sydorchuk, L, Syed, S, Syed, A, Tallon-Aguilar, L, Tamburini, A, Tamini, N, Tan, E, Tan, J, Tarasconi, A, Tartaglia, N, Tartaglia, G, Tartaglia, D, Taylor, J, Tebala, G, Teuben, M, Theodorou, A, Tolonen, M, Tomasicchio, G, Toro, A, Torre, B, Triantafyllou, T, Trigiante Trigiante, G, Tripepi, M, Trostchansky, J, Tsekouras, K, Turrado-Rodriguez, V, Tutino, R, Uccelli, M, Uchikov, P, Ugarte-Sierra, B, Ukkonen, M, Vailas, M, Vassiliu, P, Vazquez, A, Vazquez, R, Verde, J, Veroux, M, Vigano, J, Vilallonga, R, Visconti, D, Vittori, A, Waledziak, M, Wannatoop, T, Widmer, L, Wilson, M, Wong, T, Xenaki, S, Yu, B, Yule, S, Zachariah, S, Zacharis, G, Zaghi, C, Zakaria, A, Zambrano, D, Zampitis, N, Zampogna, B, Zangha, S, Zapsalis, K, Zattoni, F, Zese, M, Farre, S, Pegoraro, V, Zantedeschi, M, Reitano, E, Pizzocaro, E, Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), and The Team Dynamics Study Group
- Subjects
Settore SECS-P/10 - Organizzazione Aziendale ,Settore MED/18 - Chirurgia Generale ,Settore SECS-P/07 - Economia Aziendale ,Emergency Medicine ,Clinical decision-making ,Patient-centric care ,Shared decision-making ,Survey ,Trauma and emergency surgery ,Surgery ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
Background Shared decision-making (SDM) between clinicians and patients is one of the pillars of the modern patient-centric philosophy of care. This study aims to explore SDM in the discipline of trauma and emergency surgery, investigating its interpretation as well as the barriers and facilitators for its implementation among surgeons. Methods Grounding on the literature on the topics of the understanding, barriers, and facilitators of SDM in trauma and emergency surgery, a survey was created by a multidisciplinary committee and endorsed by the World Society of Emergency Surgery (WSES). The survey was sent to all 917 WSES members, advertised through the society’s website, and shared on the society’s Twitter profile. Results A total of 650 trauma and emergency surgeons from 71 countries in five continents participated in the initiative. Less than half of the surgeons understood SDM, and 30% still saw the value in exclusively engaging multidisciplinary provider teams without involving the patient. Several barriers to effectively partnering with the patient in the decision-making process were identified, such as the lack of time and the need to concentrate on making medical teams work smoothly. Discussion Our investigation underlines how only a minority of trauma and emergency surgeons understand SDM, and perhaps, the value of SDM is not fully accepted in trauma and emergency situations. The inclusion of SDM practices in clinical guidelines may represent the most feasible and advocated solutions.
- Published
- 2023
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40. Irregular green netting of eggplant fruit peel: a domestication trait controlled by SmGLK2 with potential for fruit colour diversification.
- Author
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Arrones A, Manrique S, Gomis-Cebolla J, Baraja-Fonseca V, Plazas M, Prohens J, Portis E, Barchi L, Giuliano G, Gramazio P, and Vilanova S
- Subjects
- Pigmentation genetics, Chlorophyll metabolism, Color, Solanum melongena genetics, Fruit genetics, Domestication, Plant Proteins genetics, Plant Proteins metabolism
- Abstract
The distribution of chlorophylls in eggplant (Solanum melongena) peel exhibits either a uniform pattern or an irregular green netting pattern. The latter, manifested as a gradient of dark green netting that is intensified in the proximal part of the fruit on a pale green background, is common in wild relatives and some eggplant landraces. Despite the selection of uniform chlorophylls during domestication, the netting pattern contributes to a greater diversity of fruit colours. Here, we used over 2300 individuals from different populations, including a multi-parent advanced generation inter-cross population for candidate genomic region identification, an F2 population for bulked segregant analysis by sequencing, and advanced backcrosses for edges-to-core fine-mapping, to identify SmGLK2 gene as responsible for the irregular netting in eggplant fruits. We also analysed the gene sequence of 178 S. melongena accessions and 22 wild relative species for tracing the evolutionary changes that the gene has undergone during domestication. Three different mutations were identified leading to the absence of netting. The main causative indel induces a premature stop codon disrupting the protein conformation and function, which was confirmed by western blot analysis and confocal microscopy observations. SmGLK2 has a major role in regulating chlorophyll biosynthesis in eggplant fruit peel., (© The Author(s) 2024. Published by Oxford University Press on behalf of the Society for Experimental Biology.)
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- 2024
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41. Integrated analyses of the transmission history of SARS-CoV-2 and its association with molecular evolution of the virus underlining the pandemic outbreaks in Italy, 2019-2023.
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Cella E, Fonseca V, Branda F, Tosta S, Moreno K, Schuab G, Ali S, Slavov SN, Scarpa F, Santos LA, Kashima S, Wilkinson E, Tegally H, Mavian C, Borsetti A, Caccuri F, Salemi M, de Oliveira T, Azarian T, de Filippis AMB, Alcantara LCJ, Ceccarelli G, Caruso A, Colizzi V, Marcello A, Lourenço J, Ciccozzi M, and Giovanetti M
- Subjects
- Italy epidemiology, Humans, Pandemics, Disease Outbreaks, SARS-CoV-2 genetics, COVID-19 transmission, COVID-19 epidemiology, COVID-19 virology, Evolution, Molecular, Genome, Viral, Phylogeny
- Abstract
Background: Italy was significantly affected by the COVID-19 pandemic, experiencing multiple waves of infection following the sequential emergence of new variants. Understanding the transmission patterns and evolution of SARS-CoV-2 is vital for future preparedness., Methods: We conducted an analysis of viral genome sequences, integrating epidemiological and phylodynamic approaches, to characterize how SARS-CoV-2 variants have spread within the country., Results: Our findings indicate bidirectional international transmission, with Italy transitioning between importing and exporting the virus. Italy experienced four distinct epidemic waves, each associated with a significant reduction in fatalities from 2021 to 2023. These waves were primarily driven by the emergence of VOCs such as Alpha, Delta, and Omicron, which were reflected in observed transmission dynamics and effectiveness of public health measures., Conclusions: The changing patterns of viral spread and variant prevalence throughout Italy's pandemic response underscore the continued importance of flexible public health strategies and genomic surveillance, both of which are crucial for tracking the evolution of variants and adapting control measures effectively to ensure preparedness for future outbreaks., Competing Interests: Declarations of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
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- 2024
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42. Tracing the evolution of the chikungunya virus in Argentina, 2016-2023: independent introductions and prominence of Latin American lineages.
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Fabbri C, Giovanetti M, Luppo V, Fonseca V, Garcia J, Barulli C, Feroci M, Perrone S, Casoni D, Giamperetti S, Alvarez Lopez MC, Foussal MD, Figueredo M, Salvatierra K, Lejona S, Ruiz Diaz N, Castro G, Bravo G, Jackel N, Sen C, Poklepovich Caride T, Franco L, Giovachini C, Mendez Rico J, Alcantara LCJ, and Morales MA
- Subjects
- Argentina epidemiology, Humans, Genome, Viral, Latin America epidemiology, Whole Genome Sequencing, Spatio-Temporal Analysis, Genetic Variation, Chikungunya virus genetics, Chikungunya virus classification, Chikungunya virus isolation & purification, Chikungunya Fever epidemiology, Chikungunya Fever virology, Chikungunya Fever transmission, Phylogeny, Genotype, Evolution, Molecular
- Abstract
Chikungunya virus (CHIKV) has emerged as a significant public health concern due to its rapid spread and potential for causing debilitating epidemics. In Argentina, the virus has garnered attention since its introduction to the Americas in 2013, due to its growing incidence and impact in neighbouring countries. Here we present a comprehensive analysis of the spatiotemporal dynamics of CHIKV in Argentina, focusing on the evolutionary trajectory of its genetic variants. Through a combination of active surveillance, screening of historical and recent samples, and whole-genome sequencing, we traced the evolutionary history of CHIKV lineages circulating within the country. Our results reveal that two distinct genotypes circulated in Argentina: The Asian lineage during the 2016 epidemic and the ECSA lineage in 2023. This distribution reflects the dominance of particular variants across Latin America. Since 2023, the ECSA lineage has led to a surge in cases throughout the Americas, marking a significant shift. The replacement of lineages in the American region constitutes a major epidemiological event, potentially affecting the dynamics of virus transmission and the clinical outcomes in impacted populations. The spatiotemporal analysis highlights CHIKV's distribution across Argentina and underscores the significant role of human mobility, especially when considering recent epidemics in neighbouring countries such as Paraguay and Uruguay, which have facilitated the spread and introduction of the viral strain into different districts. By integrating epidemiological data with genomic insights, we elucidate the patterns of virus dissemination, highlighting key areas of transmission and potential factors contributing to its spread.
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- 2024
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43. Genomic and eco-epidemiological investigations in Uruguay reveal local Chikungunya virus transmission dynamics during its expansion across the Americas in 2023.
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Burgueño A, Giovanetti M, Fonseca V, Morel N, Lima M, Castro E, Guimarães NR, Iani FCM, Bormida V, Cortinas MN, Ramas V, Coppola L, Bento AI, Franco L, Rico JM, Lourenço J, Junior Alcantara LC, and Chiparelli H
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- Uruguay epidemiology, Americas epidemiology, Disease Outbreaks, Genomics, Chikungunya virus genetics
- Abstract
Uruguay experienced its first Chikungunya virus outbreak in 2023, resulting in a significant burden to its healthcare system. We conducted analysis based on real-time genomic surveillance (30 novel whole genomes) to offer timely insights into recent local transmission dynamics and eco-epidemiological factors behind its emergence and spread in the country.
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- 2024
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44. Proteomic Signature of Body Mass Index and Risk of Type 2 Diabetes.
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Wang X, Ma H, Kou M, Heianza Y, Fonseca V, and Qi L
- Abstract
The obesity diagnosis by body mass index (BMI) exhibits considerable interindividual heterogeneity in metabolic phenotypes and risk of developing type 2 diabetes (T2D). We investigated the association of proteomic signature of BMI and T2D and examined whether the proteomic signature of BMI improves prediction of T2D risk. This study included 41,427 adults in the UK Biobank who were free of T2D at baseline and had complete data on proteomics metrics assessed by antibody based Olink assay. The main exposure was a proteomic BMI score (pro-BMI score) calculated from 67 pre-identified plasma proteins associated with BMI. During a median follow-up of 13.7 years, 2,030 incident events of T2D were documented. We observed that a higher proteomic BMI (pro-BMI) score was significantly associated with a higher risk of T2D independent of actual BMI, waist-to-hip ratio, and polygenic risk score for BMI (hazard ratio (HR) comparing the highest with the lowest quartiles was 3.81, 95% CI, 3.08 - 4.71). Pro- BMI score significantly increased the C index when added to a reference model with age, sex, and BMI (C index change, 0.023 [95%CI, 0.018 to 0.027]). Proteomic signature of BMI is significantly associated with the risk of T2D independent of BMI, WHR and genetic susceptibility to obesity. When added to actual BMI, the proteomic signature of BMI provides significant but modest improvement in discrimination., (© 2024 by the American Diabetes Association.)
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- 2024
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45. Stress Maneuver for Basilar Invagination Reduction: A Technical Report.
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Domingos Silva E Reis MT, Dantas F, Teodoro Lacerda WJ, Rivelli da Fonseca V, Coelho Barroso PM, Reis de Oliveira GH, and Rolemberg Dantas FL
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Background: Basilar invagination (BI) is a prolapse of the odontoid process cranially and posteriorly towards the foramen magnum. Several surgical treatment options are available for this condition. Herein, we describe a stress maneuver technique for BI reduction using a single-stage posterior approach., Methods: We described the case of a 56-year-old male diagnosed with type A BI and brainstem compression, who was treated with posterior fossa decompression and occipitocervical fusion. The BI was reduced intraoperatively using a stress maneuver, and cranial traction or atlantoaxial joint distraction was not necessary., Results: Postoperative imaging revealed a reduction of the odontoid process and adequate brainstem decompression. The patient showed progressive improvement of his symptoms., Conclusions: In selected cases, stress maneuvers for BI reduction can be a less morbid, easier, and replicable option within the already existing technical arsenal., (Copyright © 2024. Published by Elsevier Inc.)
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- 2024
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46. Fatal Oropouche Virus Infections in Nonendemic Region, Brazil, 2024.
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Bandeira AC, Pereira FM, Leal A, Santos SPO, Barbosa AC, Souza MSPL, de Souza DR, Guimaraes N, Fonseca V, Giovanetti M, Alcantara LCJ, Lessa AAA, Saavedra RC, Tomé LMR, Iani FCM, Barros RM, Purificação SMO, de Jesus JP, Fonseca RR, and Araújo MLV
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- Humans, Brazil epidemiology, Female, Fatal Outcome, Adult, Middle Aged, Bunyaviridae Infections epidemiology, Orthobunyavirus
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We report acute Oropouche virus infections in 2 previously healthy women from a nonendemic region of Brazil outside the Amazon Basin. Infections rapidly progressed to hemorrhagic manifestations and fatal outcomes in 4-5 days. These cases highlight the critical need for enhanced surveillance to clarify epidemiology of this neglected disease.
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- 2024
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47. Dynamics and ecology of a multi-stage expansion of Oropouche virus in Brazil.
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Tegally H, Dellicour S, Poongavanan J, Mavian C, Dor G, Fonseca V, Tagliamonte MS, Dunaiski M, Moir M, Wilkinson E, de Albuquerque CFC, Frutuoso LCV, Holmes EC, Baxter C, Lessells R, Kraemer MUG, Lourenço J, Alcantara LCJ, de Oliveira T, and Giovanetti M
- Abstract
In March 2024, the Pan American Health Organization (PAHO) issued an alert in response to a rapid increase in Oropouche fever cases across South America. Brazil has been particularly affected, reporting a novel reassortant lineage of the Oropouche virus (OROV) and expansion to previously non-endemic areas beyond the Amazon Basin. Utilising phylogeographic approaches, we reveal a multi-scale expansion process with both short and long-distance dispersal events, and diffusion velocities in line with human-mediated jumps. We identify forest cover, banana and cocoa cultivation, temperature, and human population density as key environmental factors associated with OROV range expansion. Using ecological niche modelling, we show that OROV circulated in areas of enhanced ecological suitability immediately preceding its explosive epidemic expansion in the Amazon. This likely resulted from the virus being introduced into simultaneously densely populated and environmentally favourable regions in the Amazon, such as Manaus, leading to an amplified epidemic and spread beyond the Amazon. Our study provides valuable insights into the dispersal and ecological dynamics of OROV, highlighting the role of human mobility in colonisation of new areas, and raising concern over high viral suitability along the Brazilian coast., Competing Interests: Competing interests: We declare no conflict of interest.
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- 2024
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48. A genome-wide association study identifies genetic determinants of hemoglobin glycation index with implications across sex and ethnicity.
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House JS, Breeyear JH, Akhtari FS, Evans V, Buse JB, Hempe J, Doria A, Mychaleckyi JC, Fonseca V, Shi M, Li C, Liu S, Kelly TN, Rotroff D, and Motsinger-Reif AA
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- Humans, Male, Female, Middle Aged, Sex Factors, Diabetes Mellitus, Type 2 genetics, Diabetes Mellitus, Type 2 metabolism, Ethnicity genetics, Aged, Biomarkers blood, Genotype, Genetic Predisposition to Disease, Genome-Wide Association Study, Polymorphism, Single Nucleotide, Glycated Hemoglobin analysis, Glycated Hemoglobin metabolism, Glycated Hemoglobin genetics
- Abstract
Introduction: We investigated the genetic determinants of variation in the hemoglobin glycation index (HGI), an emerging biomarker for the risk of diabetes complications., Methods: We conducted a genome-wide association study (GWAS) for HGI in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial ( N = 7,913) using linear regression and additive genotype encoding on variants with minor allele frequency greater than 3%. We conducted replication analyses of top findings in the Atherosclerosis Risk in Communities (ARIC) study with inverse variance-weighted meta-analysis. We followed up with stratified GWAS analyses by sex and self-reported race., Results: In ACCORD, we identified single nucleotide polymorphisms (SNPs) associated with HGI, including a peak with the strongest association at the intergenic SNP rs73407935 (7q11.22) ( P = 5.8e-10) with a local replication in ARIC. In black individuals, the variant rs10739419 on chromosome 9 in the Whirlin ( WHRN ) gene formally replicated (meta- P = 2.2e-9). The SNP-based heritability of HGI was 0.39 ( P < 1e-10). HGI had significant sex-specific associations with SNPs in or near GALNT11 in women and HECW2 in men. Finally, in Hispanic participants, we observed genome-wide significant associations with variants near USF1 and NXNL2/SPIN1 ., Discussion: Many HGI-associated SNPs were distinct from those associated with fasting plasma glucose or HbA1c, lending further support for HGI as a distinct biomarker of diabetes complications. The results of this first evaluation of the genetic etiology of HGI indicate that it is highly heritable and point to heterogeneity by sex and race., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 House, Breeyear, Akhtari, Evans, Buse, Hempe, Doria, Mychaleckyi, Fonseca, Shi, Li, Liu, Kelly, Rotroff and Motsinger-Reif.)
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- 2024
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49. Unraveling the Complexity of Chikungunya Virus Infection Immunological and Genetic Insights in Acute and Chronic Patients.
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Fritsch H, Giovanetti M, Clemente LG, da Rocha Fernandes G, Fonseca V, de Lima MM, Falcão M, de Jesus N, de Cerqueira EM, Venâncio da Cunha R, de Oliveira Francisco MVL, de Siqueira IC, de Oliveira C, Xavier J, Ferreira JGG, Queiroz FR, Smith E, Tisoncik-Go J, Van Voorhis WC, Rabinowitz PM, Wasserheit JN, Gale M Jr, de Filippis AMB, and Alcantara LCJ
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- Humans, Female, Male, Adult, Brazil epidemiology, Middle Aged, Transcriptome genetics, Chronic Disease, Acute Disease, Chikungunya Fever genetics, Chikungunya Fever immunology, Chikungunya Fever virology, Chikungunya virus genetics, Chikungunya virus immunology
- Abstract
Background : The chikungunya virus (CHIKV), transmitted by infected Aedes mosquitoes, has caused a significant number of infections worldwide. In Brazil, the emergence of the CHIKV-ECSA genotype in 2014 posed a major public health challenge due to its association with more severe symptoms. Objectives/Methods : This study aimed to shed new light on the host immune response by examining the whole-blood transcriptomic profile of both CHIKV-acute and chronically infected individuals from Feira de Santana, Bahia, Brazil, a region heavily affected by CHIKV, Dengue, and Zika virus epidemics. Results : Our data reveal complex symptomatology characterized by arthralgia and post-chikungunya neuropathy in individuals with chronic sequelae, particularly affecting women living in socially vulnerable situations. Analysis of gene modules suggests heightened metabolic processes, represented by an increase in NADH, COX5A, COA3, CYC1, and cap methylation in patients with acute disease. In contrast, individuals with chronic manifestations exhibit a distinct pattern of histone methylation, probably mediated by NCOA3 in the coactivation of different nuclear receptors, KMT2 genes, KDM3B and TET2, and with alterations in the immunological response, majorly led by IL-17RA, IL-6R, and STAT3 Th17 genes. Conclusion : Our results emphasize the complexity of CHIKV disease progression, demonstrating the heterogeneous gene expression and symptomatologic scenario across both acute and chronic phases. Moreover, the identification of specific gene modules associated with viral pathogenesis provides critical insights into the molecular mechanisms underlying these distinct clinical manifestations.
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- 2024
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50. Exploring Dengue Infection in a Vaccinated Individual: Preliminary Molecular Diagnosis and Sequencing Insights.
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Adelino TÉR, Pedroso SHSP, Lima M, Tomé LMR, Guimarães NR, Fonseca V, Silva PESD, Moreno KMF, Silva ACAE, Pinheiro NR, Souza CSA, Alcantara LCJ, Giovanetti M, and Iani FCM
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- Humans, Child, Vaccination, Male, Serogroup, Dengue diagnosis, Dengue virology, Dengue Virus genetics, Dengue Virus immunology, Dengue Virus classification, Dengue Vaccines immunology, Dengue Vaccines administration & dosage, Dengue Vaccines genetics, Phylogeny, RNA, Viral genetics, High-Throughput Nucleotide Sequencing
- Abstract
This study examines a case involving a 7-year-old child who developed dengue symptoms following Qdenga vaccination. Despite initial negative diagnostic results, molecular analysis confirmed an infection with DENV4. Next-generation sequencing detected viral RNA from both DENV2 and DENV4 serotypes, which were identified as vaccine-derived strains using specific primers. Phylogenetic analysis further confirmed that these sequences belonged to the Qdenga vaccine rather than circulating wild-type viruses. This case underscores the critical need for precise diagnostic interpretation in vaccinated individuals to avoid misdiagnosis and to strengthen public health surveillance. A comprehensive understanding of vaccine-induced viremia is essential for refining dengue surveillance, improving diagnostic accuracy, and informing public health strategies in endemic regions.
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- 2024
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