The Oligocene marked the beginning of the present ‘icehouse’ epoch and witnessed the development and evolution of the Asian monsoon system (AMS). In this paper, the early Oligocene Ningming flora of Guangxi, southern China, is analysed to investigate the AMS based on climate proxies derived from Climate Leaf Analysis Multivariate Program (CLAMP). CLAMP results suggest that the prevailing climate experienced by the Ningming flora was humid subtropical with hot summers and warm winters. Although the record of precipitation seasonality is muted, it is about half as strong as that seen today in monsoon climates of South China, indicating a very weak monsoonal signal. Despite suggesting weak rainfall seasonality, the position of the Ningming flora in physiognomic space indicates that leaves exhibit monsoon-adapted morphologies, comparable to today's vegetation exposed to the Indonesia–Australia monsoon (I-AM) and the transitional monsoon area (influenced by the East Asia monsoon, South Asia monsoon and I-AM). Leaf architectural signatures reveal that the Ningming flora grew under a humid subtropical climate with subtle monsoon signatures. Although it is difficult to distinguish the different domains of the Asian monsoon under such a subtle monsoon influence, based on leaf signatures from southern Asia, it can be inferred that the Ningming Basin during the early Oligocene was exposed to a climate regime similar to that today influenced by the I-AM. In addition, the moist enthalpy method was applied to quantitatively reconstruct the paleoelevation of the Ningming Basin. This approach suggests a paleoelevation estimate of ~1.24–1.35 ± 0.52 km for the early Oligocene, suggesting that a drop in paleoelevation of the Ningming Basin took place after the early Oligocene (Rupelian). The CLAMP results suggest that the early Oligocene Ningming area was at a mid-altitude and experienced a humid subtropical climate with subtle monsoon signatures.