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2. Cd2+Triggered the FRET “ON”: A New Molecular Switch for the Ratiometric Detection of Cd2+with Live-Cell Imaging and Bound X-ray Structure

Author

Aich, Krishnendu, Goswami, Shyamaprosad, Das, Sangita, Mukhopadhyay, Chitrangada Das, Quah, Ching Kheng, and Fun, Hoong-Kun

Abstract

On the basis of the Förster resonance energy transfer mechanism between rhodamine and quinoline–benzothiazole conjugated dyad, a new colorimetric as well as fluorescence ratiometric probe was synthesized for the selective detection of Cd2+. The complex formation of the probe with Cd2+was confirmed through Cd2+-bound single-crystal structure. Capability of the probe as imaging agent to detect the cellular uptake of Cd2+was demonstrated here using living RAW cells.

Published
2024
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