Author: "Gehlsen, Uta" / Publication Year Range: Last 3 years - Searchworks@Jio Institute Digital Library Search Results

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Author: Gehlsen, Uta, Faust, Christiane, Blecha, Christiane, Dietrich-Ntoukas, Tina, Eberwein, Philipp, Issleib, Susanne, Meyer-ter-Vehn, Tobias, Braun, Regine, Westekemper, Henrike, and Steven, Philipp
Published: 2022
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Author: Gehlsen, Uta, Stern, Michael E., Franklin, Jeremy, Tahmaz, Volkan, Hallek, Michael, Holtick, Udo, Scheid, Christof, and Steven, Philipp
Published: 2022
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Author: Katsinas, Nikolaos, primary, Gehlsen, Uta, additional, García-Posadas, Laura, additional, Rodríguez-Rojo, Soraya, additional, Steven, Philipp, additional, González-García, María J., additional, and Enríquez-de-Salamanca, Amalia, additional
Published: 2022
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Author: Tran, Bao N., primary, Maass, Martina, additional, Musial, Gwen, additional, Stern, Michael E., additional, Gehlsen, Uta, additional, and Steven, Philipp, additional
Published: 2021
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Author: Tran, Bao N., Maass, Martina, Musial, Gwen, Stern, Michael E., Gehlsen, Uta, and Steven, Philipp
Abstract: Dry eye disease (DED) is a multifactorial disease, with limitations regarding efficacy and tolerability of applied substances. Among several candidates, the endocannabinoid system with its receptors (CB1R and CB2R) were reported to modulate inflammation, wound healing and pain, which are also core DED pathomechanisms. This study is to investigate the therapeutic responses of Δ-9 tetrahydrocannabinol (a non-selective agonist) and two selective antagonists, SR141716A (CB1R antagonist) and SR144528 (CB2R antagonist), as a topical application using a DED mouse model.
Published: 2022
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