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7 results on '"Gibelli, Maria Augusta Bento Cicaroni"'

2. Epidemiology of Neonatal Acute Respiratory Distress Syndrome: Prospective, Multicenter, International Cohort Study

Author

de Luca, Daniele, Tingay, David G., van Kaam, Anton H., van Tuijl, Minke, Courtney, Sherry E., Kneyber, Martin C. J., Tissieres, Pierre, Tridente, Ascanio, Rimensberger, Peter C., Pillow, J. Jane, Carnielli, Virgilio P., Nobile, Stefano, Shi, Yuan, Long, Chen, Barcos, Francisca, Hochberg, Amit, Crocker, Caroline E., Harrison, Allen, Perkins, Elizabeth, Mosca, Fabio, Mercadante, Domenica, Raimondi, Francesco, Capasso, Letizia, Kallio, Merja, Raschetti, Roberto, Cillis, Annagrazia, Soreze, Yohan, Black, Lachlan, Khan, Nash, Piastra, Marco, Conti, Giorgio, Danhaive, Olivier, Gibelli, Maria Augusta Bento Cicaroni, de Carvalho, Werther Brunow, Mulder, Estelle, Neonatology, ARD - Amsterdam Reproduction and Development, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), AP-HP - Hôpital Antoine Béclère [Clamart], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hypertension pulmonaire : physiopathologie et innovation thérapeutique (HPPIT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Murdoch Children's Research Institute (MCRI), University of Melbourne, Emma Children's Hospital, University of Amsterdam [Amsterdam] (UvA), University of Arkansas for Medical Sciences (UAMS), Beatrix Children's Hospital [Groningen, Pays-Bas], University Medical Center Groningen [Groningen] (UMCG), University of Groningen [Groningen], AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Manchester Metropolitan University (MMU), Hôpital Universitaire de Genève = University Hospitals of Geneva (HUG), The University of Western Australia (UWA), Telethon KIDS Institute, Dr. De Luca received funding from Chiesi Farmaceutici S.p.A., Abbvie, Vyaire, Getinge, Medtronic, Masimo, Natus, Airway Therapeutics, and Ophirex, Dr. Tingay is supported by the Victorian Government Infrastructure Support Program. Drs. Tingay and Pillow received support for article research from the National Health and Medical Research Council (NHMRC) (Australia) Fellowships GNT1053889 and GNT1077691, respectively.Dr. van Kaam’s intuition received funding from Vyaire, Mallinckrodt, and Chiesi Farmaceutici S.p.A. Dr. Kneyber received funding from the National Heart, Lung, and Blood Institute, ZonMW, Stichting Vrienden Beatrix Kinderziekenhuis, and University Medical Center Groningen. Dr. Tissieres received funding from Sanofi, Inotrem, and Sedana. Dr. Pillow’s institution received funding from the NHMRC Centre of Research Excellence, the NHMRC Senior Research Fellowship, Chiesi Farmaceutici S.p.A., and Draeger Medical, for the Neonatal ARDS Project Collaboration Group Collaborators : van Tuijl, Minke, Carnielli, Virgilio P., Nobile, Stefano, Shi, Yuan, Long, Chen, Barcos, Francisca, Hochberg, Amit, Crocker, Caroline E., Harrison, Allen, Perkins, Elizabeth, Mosca, Fabio, Mercadante, Domenica, Raimondi, Francesco, Capasso, Letizia, Kallio, Merja, Raschetti, Roberto, Cillis, Annagrazia, Soreze, Yohan, Black, Lachlan, Khan, Nash, Piastra, Marco, Conti, Giorgio, Danhaive, Olivier, Gibelli, Maria Augusta Bento Cicaroni, de Carvalho, Werther Brunow, and Mulder, Estelle

Subjects
Male, MESH: Respiratory Distress Syndrome, Critical Care and Intensive Care Medicine, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Cohort Studies, MESH: Pregnancy, Extracorporeal Membrane Oxygenation, MESH: Extracorporeal Membrane Oxygenation, cohort study Fifteen academic neonatal ICUs acute respiratory distress syndrome, Pregnancy, MESH: Child, Humans, MESH: Respiratory Distress Syndrome, Newborn, observational, Prospective Studies, Multicenter, Child, MESH: Cohort Studies, Retrospective Studies, [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics, Respiratory Distress Syndrome, Respiratory Distress Syndrome, Newborn, MESH: Humans, MESH: Infant, Newborn, respiratory failure, Infant, Newborn, MESH: Retrospective Studies, respiratory failure Prospective, acute respiratory distress syndrome, International Cohort Study, neonatal intensive care unit, MESH: Male, MESH: Prospective Studies, Prospective, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, international, Pediatrics, Perinatology and Child Health, outcome, Female, neonate, MESH: Female
Abstract

OBJECTIVES: Age-specific definitions for acute respiratory distress syndrome (ARDS) are available, including a specific definition for neonates (the "Montreux definition"). The epidemiology of neonatal ARDS is unknown. The objective of this study was to describe the epidemiology, clinical course, treatment, and outcomes of neonatal ARDS.DESIGN: Prospective, international, observational, cohort study.SETTING: Fifteen academic neonatal ICUs.PATIENTS: Consecutive sample of neonates of any gestational age admitted to participating sites who met the neonatal ARDS Montreux definition criteria.MEASUREMENTS AND MAIN RESULTS: Neonatal ARDS was classified as direct or indirect, infectious or noninfectious, and perinatal (≤ 72 hr after birth) or late in onset. Primary outcomes were: 1) survival at 30 days from diagnosis, 2) inhospital survival, and 3) extracorporeal membrane oxygenation (ECMO)-free survival at 30 days from diagnosis. Secondary outcomes included respiratory complications and common neonatal extrapulmonary morbidities. A total of 239 neonates met criteria for the diagnosis of neonatal ARDS. The median prevalence was 1.5% of neonatal ICU admissions with male/female ratio of 1.5. Respiratory treatments were similar across gestational ages. Direct neonatal ARDS (51.5% of neonates) was more common in term neonates and the perinatal period. Indirect neonatal ARDS was often triggered by an infection and was more common in preterm neonates. Thirty-day, inhospital, and 30-day ECMO-free survival were 83.3%, 76.2%, and 79.5%, respectively. Direct neonatal ARDS was associated with better survival outcomes than indirect neonatal ARDS. Direct and noninfectious neonatal ARDS were associated with the poorest respiratory outcomes at 36 and 40 weeks' postmenstrual age. Gestational age was not associated with any primary outcome on multivariate analyses.CONCLUSIONS: Prevalence and survival of neonatal ARDS are similar to those of pediatric ARDS. The neonatal ARDS subtypes used in the current definition may be associated with distinct clinical outcomes and a different distribution for term and preterm neonates.

Published
2022

3. Three-Dimensional Ultrasound Evaluation of Lung Volume in Fetuses with Abdominal Wall Defect

Author

Nishie, Estela Naomi, primary, Osmundo Junior, Gilmar de Souza, additional, Mohamed, Samirah Hosney Mahmoud, additional, Tannuri, Ana Cristina Aoun, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Carvalho, Werther Brunow de, additional, Peres, Stela Verzinhasse, additional, Francisco, Rossana Pulcineli Vieira, additional, and Brizot, Maria de Lourdes, additional

Published
2023
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5. MRSA outbreak in a Neonatal Intensive Care Unit in a developed country: importance of rapid detection of reservoirs and implementation of intervention measures

Author

Moura, Maria Luísa, primary, Rizek, Camila Fonseca, additional, Aguiar, Elisa, additional, Barros, Ana Natiele da Silva, additional, Costa, Sibeli, additional, Santos, Sania Alves dos, additional, Marchi, Ana Paula, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Tragante, Carla Regina, additional, Araújo, Maria Rita Elmor de, additional, Rossi, Flavia, additional, Guimaraes, Thais, additional, and Costa, Silvia Figueiredo, additional

Published
2022
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6. Assessment of newborn neuropsychomotor development born with exposure to SARS-CoV-2 in the perinatal period using the Bayley III scale at 6 months of age

Author

Orioli, Patricia Albertini, Johnston, Cintia, Del Bigio, Juliana Zoboli, Krebs, Vera Lucia Jornada, Pissolato, Mariana, Gibelli, Maria Augusta Bento Cicaroni, De Araujo, Orlei Ribeiro, Francisco, Rossana Pulcineli Vieira, and De Carvalho, Werther Brunow

Abstract

•The perinatal repercussions of the SARS-CoV-2 virus have not yet been elucidated.•Few reports in the literature indicate damage to the Neuro Psychomotor Development (NPMD) of children born during the COVID-19 pandemic, but its mechanisms are not clearly established.

Published
2024
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7. Differences in children and adolescents with SARS-CoV-2 infection: a cohort study in a Brazilian tertiary referral hospital.

Author

Marques HHS, Pereira MFB, Santos ACD, Fink TT, Paula CSY, Litvinov N, Schvartsman C, Delgado AF, Gibelli MABC, Carvalho WB, Odone Filho V, Tannuri U, Carneiro-Sampaio M, Grisi S, Duarte AJDS, Antonangelo L, Francisco RPV, Okay TS, Batisttella LR, Carvalho CRR, Brentani AVM, Silva CA, Eisencraft AP, Rossi Junior A, Fante AL, Cora AP, Reis AGAC, Ferrer APS, Andrade APM, Watanabe A, Gonçalves AMF, Waetge ARP, Silva CA, Ceneviva C, Lazari CDS, Abellan DM, Santos EHD, Sabino EC, Bianchini FRM, Alcantara FFP, Ramos GF, Leal GN, Rodriguez IS, Pinho JRR, Carneiro JDA, Paz JA, Ferreira JC, Ferranti JF, Ferreira JOA, Framil JVS, Silva KRD, Kanunfre KA, Bastos KLM, Galleti KV, Cristofani LM, Suzuki L, Campos LMA, Perondi MBM, Diniz MFR, Fonseca MFM, Cordon MNA, Pissolato M, Peres MS, Garanito MP, Imamura M, Dorna MB, Luglio M, Rocha MC, Aikawa NE, Degaspare NV, Sakita NK, Udsen NL, Scudeller PG, Gaiolla PVV, Severini RDSG, Rodrigues RM, Toma RK, Paula RIC, Palmeira P, Forsait S, Farhat SCL, Sakano TMS, Koch VHK, and Cobello Junior V

Subjects
Adolescent, Child, Cohort Studies, Cross-Sectional Studies, Humans, Infant, Newborn, SARS-CoV-2, Systemic Inflammatory Response Syndrome, Tertiary Care Centers, COVID-19 complications
Abstract

Objectives: To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19)., Methods: This was a cross-sectional study that included patients diagnosed with pediatric COVID-19 (aged <18 years) between April 11, 2020 and April 22, 2021. During this period, 102/5,951 (1.7%) of all admissions occurred in neonates, children, and adolescents. Furthermore, 3,962 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection samples were processed in patients aged <18 years, and laboratory-confirmed COVID-19 occurred in 155 (4%) inpatients and outpatients. Six/155 pediatric patients were excluded from the study. Therefore, the final group included 149 children and adolescents (n=97 inpatients and 52 outpatients) with positive SARS-CoV-2 results., Results: The frequencies of sore throat, anosmia, dysgeusia, headache, myalgia, nausea, lymphopenia, pre-existing chronic conditions, immunosuppressive conditions, and autoimmune diseases were significantly reduced in children and adolescents (p<0.05). Likewise, the frequencies of enoxaparin use (p=0.037), current immunosuppressant use (p=0.008), vasoactive agents (p=0.045), arterial hypotension (p<0.001), and shock (p=0.024) were significantly lower in children than in adolescents. Logistic regression analysis showed that adolescents with laboratory-confirmed COVID-19 had increased odds ratios (ORs) for sore throat (OR 13.054; 95% confidence interval [CI] 2.750-61.977; p=0.001), nausea (OR 8.875; 95% CI 1.660-47.446; p=0.011), and lymphopenia (OR 3.575; 95% CI 1.355-9.430; p=0.010), but also had less hospitalizations (OR 0.355; 95% CI 0.138-0.916; p=0.032). The additional logistic regression analysis on patients with preexisting chronic conditions (n=108) showed that death as an outcome was significantly associated with pediatric severe acute respiratory syndrome (SARS) (OR 22.300; 95% CI 2.341-212.421; p=0.007) and multisystem inflammatory syndrome in children (MIS-C) (OR 11.261; 95% CI 1.189-106. 581; p=0.035)., Conclusions: Half of the laboratory-confirmed COVID-19 cases occurred in adolescents. Individuals belonging to this age group had an acute systemic involvement of SARS-CoV-2 infection. Pediatric SARS and MIS-C were the most important factors associated with the mortality rate in pediatric chronic conditions with COVID-19.

Published
2021
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