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The electric vehicle (EV) market is expanding rapidly, highlighting the need for enhanced customer perceived value to foster loyalty and competitive differentiation. This study investigates how experience management tools can improve customer experience management in the EV sector with an emphasis on sustainable business practices and environmental sustainability. The research explores existing customer experience management methods, the necessary functions of these tools, and their effectiveness in enhancing management capabilities from the perspective of customer perceived value. A thorough literature review and empirical analysis were conducted to design and evaluate tailored experience management tools. The findings suggest that these tools can enhance customer satisfaction and loyalty by addressing key elements of perceived value, such as price perception, quality perception, and brand image. Additionally, improved customer experience management may encourage sustainable consumer behaviors by making eco-friendly EVs more appealing, supporting environmental sustainability. This research aims to bridge the gap between customer perceived value theory and its practical application in the EV industry. It offers insights for manufacturers and marketers seeking to create more engaging and sustainable customer experiences. The implications extend beyond the EV market, providing a potential framework for various industries to enhance customer perceived value through effective and sustainable experience management. [ABSTRACT FROM AUTHOR]

Jumbo phages are a group of tailed bacteriophages with large genomes and capsids. As a prototype of jumbo phage, ΦKZ infects Pseudomonas aeruginosa, a multi-drug-resistant (MDR) opportunistic pathogen leading to acute or chronic infection in immunocompromised individuals. It holds potential to be used as an antimicrobial agent and as a model for uncovering basic phage biology. Although previous low-resolution structural studies have indicated that jumbo phages may have more complicated capsid structures than smaller phages such as HK97, the detailed structures and the assembly mechanism of their capsids remain largely unknown. Here, we report a 3.5-Å-resolution cryo-EM structure of the ΦKZ capsid. The structure unveiled ten minor capsid proteins, with some decorating the outer surface of the capsid and the others forming a complex network attached to the capsid's inner surface. This network seems to play roles in driving capsid assembly and capsid stabilization. Similar mechanisms of capsid assembly and stabilization are probably employed by many other jumbo viruses. Here, the authors present the 3.5-Å-resolution cryo-EM structure of the jumbo phage ΦKZ capsid, revealing ten minor capsid proteins that are hypothesized to contribute to capsid assembly and stabilization. [ABSTRACT FROM AUTHOR]

In the era of big data, the rich data resources of the petroleum industry not only provide auxiliary decision-making support for the production and scientific research of petroleum enterprises, but also play a vital role in the digital transformation of enterprises. From the perspective of petroleum exploration data management technology, this paper divides its past development process into database technology stage, data warehouse technology stage, data lake technology stage, data integration platform stage, and special application of big data technology by combing the relevant literature. At present, it is in the initial stage of the construction of the data middle office. The core problem that needs to be solved is to match the calculation type with the most suitable computing framework, optimize the allocation of computing resources, and give full play to the processing capabilities of the data middle office.

A rapid, accurate, non-sputum-based triage test for diagnosing tuberculosis (TB) is a high-priority need. Cepheid developed a novel prototype blood test, Xpert Mycobacterium tuberculosis Host Response (Xpert-MTB-HR), which generates a TB score based on the mRNA expression of three genes. We conducted a case-control study with prospective recruitment to evaluate its accuracy in the clinic of the Wusheng County Centers for Disease Prevention and Control in China. We enrolled 149 TB patients, 248 other respiratory diseases (ORD) patients, and 193 healthy controls. In addition, whole-blood samples taken from TB patients after 2, 5, and 6 months of treatment were tested with Xpert-MTB-HR to evaluate its ability to monitor treatment response. Xpert-MTB-HR discriminated between TB and healthy controls with an area under the curve (AUC) of 0.912 (95% CI, 0.878-0.945). With the specificity of 70% envisioned for a triage test, its sensitivity was 90.1% (84.9%-94.6%). Xpert-MTB-HR discriminated between TB and ORD with an AUC of 0.798 (0.750-0.847), and at specificity of 70%, the sensitivity was only 75.8% (68.5%-82.8%). In patients determined by Ultra to have medium or high sputum bacillary loads, with specificity of 70%, the sensitivity for discriminating patients with TB from healthy controls was 100.0% (100.0-100.0) and from patients with ORD, 95.1% (89.8-100.0). The TB scores generally increased by 2 months of treatment and then remained stable. Xpert-MTB-HR met the criteria for a triage test to discriminate between TB and healthy controls, but not between TB and ORD, except when limited to patients with high sputum bacillary loads. Xpert-MTB-HR showed promise for monitoring response to treatment but needs to be further evaluated in larger prospective studies., Competing Interests: The authors declare no conflict of interest.

With the increasing demand for pollinating services, the wellness of honeybees has received widespread attention. Recent evidence indicated honeybee health might be posed a potential threat by widely used neonicotinoids worldwide. However, little is known about the molecular mechanism of these insecticides in honeybees especially at an enantiomeric level. In this study, we selected two species of bees, Apis mellifera ( A. mellifera ) and Apis cerana ( A. cerana ), to assess the toxicity and molecular mechanism of neonicotinoid dinotefuran and its enantiomers. The results showed that S -dinotefuran was more toxic than rac -dinotefuran and R -dinotefuran to honeybees by oral and contact exposures as much as 114 times. A. cerana was more susceptible to highly toxic enantiomer S -dinotefuran. S -dinotefuran induced the immune system response in A. cerana after 48 h exposure and significant changes were observed in the neuronal signaling of A. mellifera under three forms of dinotefuran exposure. Moreover, molecular docking also revealed that S -dinotefuran formed more hydrogen bonds than R -dinotefuran with nicotinic acetylcholine receptor, indicating the higher toxicity of S -dinotefuran. Data provided here show that R -dinotefuran may be a safer alternative to control pests and protect pollinators than rac -dinotefuran.