400 results on '"He, Qiaojun"'
Search Results
2. Regorafenib inhibits EphA2 phosphorylation and leads to liver damage via the ERK/MDM2/p53 axis
3. Dabrafenib alleviates hepatotoxicity caused by lenvatinib via inhibiting the death receptor signaling pathway
4. Macrophage senescence in health and diseases
5. Insights into the role of derailed endocytic trafficking pathway in cancer: From the perspective of cancer hallmarks
6. Cediranib enhances the transcription of MHC-I by upregulating IRF-1
7. Development and safety of PI3K inhibitors in cancer
8. Cancer-associated fibroblasts drive early pancreatic cancer cell invasion via the SOX4/MMP11 signalling axis
9. Strategies to synergize PD-1/PD-L1 targeted cancer immunotherapies to enhance antitumor responses in ovarian cancer
10. Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells
11. The palmitoyltransferase ZDHHC21 regulates oxidative phosphorylation to induce differentiation block and stemness in AML
12. Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA
13. Opportunities and challenges of incretin-based hypoglycemic agents treating type 2 diabetes mellitus from the perspective of physiological disposition
14. A practical “preTACs-cytoblot” platform accelerates the streamlined development of PROTAC-based protein degraders
15. Fingolimod exerts in vitro anticancer activity against hepatocellular carcinoma cell lines via YAP/TAZ suppression
16. Dasatinib causes keratinocyte apoptosis via inhibiting high mobility group Box 1-mediated mitophagy
17. Deubiquitination complex platform: A plausible mechanism for regulating the substrate specificity of deubiquitinating enzymes
18. Butein suppresses PD-L1 expression via downregulating STAT1 in non-small cell lung cancer
19. Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes
20. Deneddylation of PML/RARα reconstructs functional PML nuclear bodies via orchestrating phase separation to eradicate APL
21. Rutin attenuates ensartinib-induced hepatotoxicity by non-transcriptional regulation of TXNIP
22. CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses
23. CT-707 overcomes hypoxia-mediated sorafenib resistance in Hepatocellular carcinoma by inhibiting YAP signaling
24. Design, synthesis and biological evaluation of new dihydropyridine derivatives as PD-L1 degraders for enhancing antitumor immunity
25. Protective effects of six different pectic polysaccharides on DSS-induced IBD in mice
26. Design, synthesis, and biological evaluation of quinazoline derivatives with covalent reversible warheads as potential FGFR4 inhibitors
27. Noncovalent CDK12/13 dual inhibitors-based PROTACs degrade CDK12-Cyclin K complex and induce synthetic lethality with PARP inhibitor
28. Unraveling the treatment effects of huanglian jiedu decoction on drug-induced liver injury based on network pharmacology, molecular docking and experimental validation.
29. Multi-constraint molecular generation based on conditional transformer, knowledge distillation and reinforcement learning
30. Design, synthesis and biological evaluation of quinazoline derivatives as potent and selective FGFR4 inhibitors
31. Bisdemethoxycurcumin alleviates vandetanib-induced cutaneous toxicity in vivo and in vitro through autophagy activation
32. Correction: LncRNA-MM2P Identified as a Modulator of Macrophage M2 Polarization
33. Anti-inflammation effects of highly purified low-Mw RG-I pectins on LPS-activated macrophages
34. Defining therapeutic targets for renal fibrosis: Exploiting the biology of pathogenesis
35. Opportunities and challenges of incretins-based hypoglycemic agents treating of T2DM from the insight of physiological disposition
36. SynergyX: a multi-modality mutual attention network for interpretable drug synergy prediction
37. Josephin domain containing 2 (JOSD2) promotes lung cancer by inhibiting LKB1 (Liver kinase B1) activity
38. Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy
39. Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling
40. Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling
41. ASFP (Artificial Intelligence based Scoring Function Platform): a web server for the development of customized scoring functions
42. Protective effect of borneol on the cutaneous toxicity of gilteritinib
43. Author correction to ‘Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA’ [Acta Pharmaceutica Sinica B 13 (2023) 2585–2600]
44. Deubiquitinating enzyme JOSD2 affects susceptibility of non-small cell lung carcinoma cells to anti-cancer drugs through DNA damage repair
45. Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment
46. The Frontline of Alternatives to Animal Testing: Novel In vitro Skin Model Application in Drug Development and Evaluation
47. Inhibition of PRKAA/AMPK (Ser485/491) phosphorylation by crizotinib induces cardiotoxicity via perturbing autophagosome-lysosome fusion.
48. KLF12 transcriptionally regulates PD‐L1 expression in non‐small cell lung cancer.
49. TransFoxMol: predicting molecular property with focused attention
50. Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13‐Mediated Stabilization of Bcl‐XL
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