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Your search keyword '"Hosoda, Kiminori"' showing total 23 results
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23 results on '"Hosoda, Kiminori"'

5. Glucagon-like Peptide-1 analogues and delipidation of coronary atheroma in statin-treated type 2 diabetic patients with coronary artery disease: The prespecified sub-analysis of the OPTIMAL randomized clinical trial

Author

Kataoka, Yu, Kitahara, Satoshi, Funabashi, Sayaka, Makino, Hisashi, Matsubara, Masaki, Matsuo, Miki, Omura-Ohata, Yoko, Koezuka, Ryo, Tochiya, Mayu, Tamanaha, Tamiko, Tomita, Tsutomu, Honda-Kohmo, Kyoko, Noguchi, Michio, Murai, Kota, Sawada, Kenichiro, Iwai, Takamasa, Matama, Hideo, Honda, Satoshi, Fujino, Masashi, Nakao, Kazuhiro, Yoneda, Shuichi, Takagi, Kensuke, Otsuka, Fumiyuki, Asaumi, Yasuhide, Hosoda, Kiminori, Nicholls, Stephen J., Yasuda, Satoshi, and Noguchi, Teruo

Published
2024
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6. DAPagliflozin for the attenuation of albuminuria in Patients with hEaRt failure and type 2 diabetes (DAPPER study): a multicentre, randomised, open-label, parallel-group, standard treatment-controlled trial

Author

Yoshihara, Fumiki, Imazu, Miki, Kawabata, Takanori, Omae, Katsuhiro, Izumi, Chisato, Kanzaki, Hideaki, Amaki, Makoto, Okada, Atsushi, Amano, Masashi, Moriuchi, Kenji, Ito, Shin, Hosoda, Kiminori, Makino, Hisashi, Omura-Ohata, Yoko, Tamanaha, Tamiko, Koezuka, Ryo, Noguchi, Michio, Arisato, Tetsuya, Noguchi, Teruo, Tahara, Yoshio, Kataoka, Yu, Asaumi, Yasuhide, Fujino, Masashi, Otsuka, Fumiyuki, Yoneda, Shuichi, Honda, Satoshi, Miura, Hiroyuki, Sakuma, Ichiro, Hiroi, Yukio, Hara, Hisao, Yamamoto, Masaya, Okazaki, Toru, Nakagawa, Takashi, Kubota, Shuji, Torii, Shunsuke, Yamamoto, Jumpei, Miyake, Wataru, Nagai, Ran, Ishiwata, Mai, Okazaki, Osamu, Ishiguro, Chizuru, Shiraiwa, Toshihiko, Nishioka, Norio, Maeno, Yoshifumi, Yamamoto, Kaoru, Yoshida, Yoko, Shiraiwa, Yuka, Fujii, Kenshi, Iwakura, Katsuomi, Okamura, Atsunori, Hirao, Yuko, Tanaka, Koji, Iwamoto, Mutsumi, Tanaka, Nobuaki, Okada, Masato, Sumiyoshi, Akinori, Tanaka, Kota, Watanabe, Satoshi, Harada, Shinichi, Kashiyama, Toshikazu, Tomonaga, Osamu, Kobayashi, Koichi, Ishiki, Ryoji, Yamamoto, Dai, Ito, Tadahiro, Takihata, Masahiro, Yumoto, Kazuhiko, Fukuzawa, Tomoyuki, Takase, Hiroyuki, Hayashi, Kazusa, Himi, Toshiharu, Hyodo, Yusuke, Ishibashi, Ryoichi, Shimizu, Ikki, Murakami, Tsutomu, Ikari, Yuji, Ohno, Yohei, Sakama, Susumu, Nakamura, Norihito, Miyamoto, Junichi, Torii, Sho, Ijichi, Takeshi, Lee, Kyong Hee, Wagatsuma, Kenji, Nii, Hideo, Uchida, Yasuto, Sato, Katsuhiko, Hiramatsu, Takeyuki, Takada, Yasunobu, Akabame, Satoshi, Koide, Masahiro, Kitajima, Hiroki, Kato, Yukinori, Sogabe, Koji, Fukui, Kento, Kogure, Masaya, Kishi, Akio, Hata, Shiro, Shinboku, Hiroki, Muroya, Takahiro, Sonoda, Koichiro, Asakura, Masanori, and Kitakaze, Masafumi

Published
2023
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7. The effect of continuous glucose monitoring-guided glycemic control on progression of coronary atherosclerosis in type 2 diabetic patients with coronary artery disease: The OPTIMAL randomized clinical trial

Author

Kataoka, Yu, Kitahara, Satoshi, Funabashi, Sayaka, Makino, Hisashi, Matsubara, Masaki, Matsuo, Miki, Omura-Ohata, Yoko, Koezuka, Ryo, Tochiya, Mayu, Tamanaha, Tamiko, Tomita, Tsutomu, Honda-Kohmo, Kyoko, Noguchi, Michio, Maruki, Maki, Kanai, Emi, Murai, Kota, Iwai, Takamasa, Sawada, Kenichiro, Matama, Hideo, Honda, Satoshi, Fujino, Masashi, Yoneda, Syuichi, Takagi, Kensuke, Otsuka, Fumiyuki, Asaumi, Yasuhide, Hosoda, Kiminori, Nicholls, Stephen J., Yasuda, Satoshi, and Noguchi, Teruo

Published
2023
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8. Prevention of hypoglycemia by intermittent-scanning continuous glucose monitoring device combined with structured education in patients with type 1 diabetes mellitus: A randomized, crossover trial

Author

Murata, Takashi, Hosoda, Kiminori, Kunihiro Nishimura, Miyamoto, Yoshihiro, Sakane, Naoki, Satoh-Asahara, Noriko, Toyoda, Masao, Hirota, Yushi, Matsuhisa, Munehide, Kuroda, Akio, Kato, Ken, Kouyama, Ryuji, Miura, Junnosuke, Tone, Atsuhito, Kasahara, Masato, Kasama, Shu, Suzuki, Shota, Ito, Yukie, Watanabe, Tomokazu, Suganuma, Akiko, Shen, Zhuo, Kobayashi, Hiroko, Takagi, Satoshi, Hoshina, Sari, Shimura, Kanako, Tsuchida, Yukiko, Kimura, Moritsugu, Saito, Nobumichi, Shimada, Akira, Oikawa, Yoichi, Satomura, Atsushi, Haisa, Akifumi, Kawashima, Satoshi, Meguro, Shu, Itoh, Hiroshi, Saisho, Yoshifumi, Irie, Junichiro, Tanaka, Masami, Mitsuishi, Masanori, Nakajima, Yuya, Inaishi, Jun, Kinouchi, Kenichiro, Yamaguchi, Shintaro, Itoh, Arata, Sugiyama, Kazutoshi, Yagi, Kazuma, Tsuchiya, Tami, Kodani, Noriko, Shimizu, Ikki, Fukuda, Tetsuya, Kusunoki, Yoshiki, Katsuno, Tomoyuki, Matoba, Yuka, Hitaka, Yumi, Abe, Kentaro, Tanaka, Natsuko, Taniguchi, Ryoko, Nagao, Toshihiko, Hida, Kazuyuki, Iseda, Izumi, Takeda, Masaya, Matsushita, Yuichi, Tenta, Masafumi, Tanaka, Tsuyoshi, Kouyama, Kunichi, and Fukunaga, Michiru

Published
2023
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11. Comparison of canagliflozin and teneligliptin on energy intake and body weight in Japanese patients with Type 2 diabetes: a subanalysis of the CANTABILE study.

Author

Isogawa, Masahiro, Makino, Hisashi, Son, Cheol, Nishimura, Kunihiro, Hirata, Takumi, Kasama, Shu, Miyamoto, Yoshihiro, Noguchi, Michio, Kasahara, Masato, and Hosoda, Kiminori

Subjects
CANAGLIFLOZIN, FOOD consumption, GLYCOSYLATED hemoglobin, SECONDARY analysis, RESEARCH funding, BODY weight, GLYCEMIC control, TREATMENT effectiveness, PROTEASE inhibitors, TYPE 2 diabetes, COMPARATIVE studies, PHARMACODYNAMICS
Abstract

Background: While the Sodium-glucose co-transporter 2 (SGLT2) inhibitors and dipeptidyl peptidase-4 (DPP4) are widely used for the glycemic control in type 2 diabetes mellitus, the differences in the effects of SGLT2 inhibitors and DPP4 inhibitors on energy intake and diabetes-related indicators are unclear. Methods: This was a subanalysis of the CANTABILE study which compared the effects of canagliflozin and teneligliptin on metabolic factors in Japanese patients with Type 2 diabetes. The changes at 24 weeks from the baseline of the diabetes-related indicators including Hemoglobin A1c (HbA1c), energy intake and body weight were compared between the canagliflozin and teneligliptin groups. Results: Seventy-five patients in the canagliflozin group and 70 patients in the teneligliptin group were analyzed. A significant decrease in HbA1c was observed in both groups. In the teneligliptin group, although energy intake was significantly reduced, there was no significant change in body weight. Conversely, in the canagliflozin group, although energy intake tended to increase, body weight significantly decreased. Conclusion: Canagliflozin and teneligliptin have different effects on the dietary status of patients with Type 2 diabetes. Our result suggests that canagliflozin can manage blood glucose without weight gain, even with increased energy intake. [ABSTRACT FROM AUTHOR]

Published
2024
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13. To Use or Not to Use a Self-monitoring of Blood Glucose System? Real-world Flash Glucose Monitoring Patterns Using a Cluster Analysis of the FGM-Japan Study

Author

Sakane, Naoki, primary, Hirota, Yushi, additional, Yamamoto, Akane, additional, Miura, Junnosuke, additional, Takaike, Hiroko, additional, Hoshina, Sari, additional, Toyoda, Masao, additional, Saito, Nobumichi, additional, Hosoda, Kiminori, additional, Matsubara, Masaki, additional, Tone, Atsuhito, additional, Kawashima, Satoshi, additional, Sawaki, Hideaki, additional, Matsuda, Tomokazu, additional, Domichi, Masayuki, additional, Suganuma, Akiko, additional, Sakane, Seiko, additional, and Murata, Takashi, additional

Published
2023
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14. Association of scan frequency with CGM-derived metrics and influential factors in adults with type 1 diabetes mellitus

Author

Sakane, Naoki, primary, Hirota, Yushi, additional, Yamamoto, Akane, additional, Miura, Junnosuke, additional, Takaike, Hiroko, additional, Hoshina, Sari, additional, Toyoda, Masao, additional, Saito, Nobumichi, additional, Hosoda, Kiminori, additional, Matsubara, Masaki, additional, Tone, Atsuhito, additional, Kawashima, Satoshi, additional, Sawaki, Hideaki, additional, Matsuda, Tomokazu, additional, Domichi, Masayuki, additional, Suganuma, Akiko, additional, Sakane, Seiko, additional, and Murata, Takashi, additional

Published
2023
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15. Factors associated with hemoglobin glycation index in adults with type 1 diabetes mellitus: The FGM‐Japan study

Author

Sakane, Naoki, primary, Hirota, Yushi, additional, Yamamoto, Akane, additional, Miura, Junnosuke, additional, Takaike, Hiroko, additional, Hoshina, Sari, additional, Toyoda, Masao, additional, Saito, Nobumichi, additional, Hosoda, Kiminori, additional, Matsubara, Masaki, additional, Tone, Atsuhito, additional, Kawashima, Satoshi, additional, Sawaki, Hideaki, additional, Matsuda, Tomokazu, additional, Domichi, Masayuki, additional, Suganuma, Akiko, additional, Sakane, Seiko, additional, and Murata, Takashi, additional

Published
2023
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16. Diabetic microvascular complications predicts non‐heart failure with reduced ejection fraction in type 2 diabetes

Author

Tochiya, Mayu, primary, Makino, Hisashi, additional, Tamanaha, Tamiko, additional, Omura‐Ohata, Yoko, additional, Matsubara, Masaki, additional, Koezuka, Ryo, additional, Noguchi, Michio, additional, Tomita, Tsutomu, additional, Asaumi, Yasuhide, additional, Miyamoto, Yoshihiro, additional, Yasuda, Satoshi, additional, and Hosoda, Kiminori, additional

Published
2023
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20. Impaired leptin responsiveness in the nucleus accumbens of leptin-overexpressing transgenic mice with dysregulated sucrose and lipid preference independent of obesity

Author

Nomura, Hidenari, primary, Son, Cheol, additional, Aotani, Daisuke, additional, Shimizu, Yoshiyuki, additional, Katsuura, Goro, additional, Noguchi, Michio, additional, Kusakabe, Toru, additional, Tanaka, Tomohiro, additional, Miyazawa, Takashi, additional, Hosoda, Kiminori, additional, and Nakao, Kazuwa, additional

Published
2022
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21. Possible Relationship between the Deteriorated Accuracy of Intermittent-Scanning Continuous Glucose Monitoring Device and the Contact Dermatitis: Post-hoc analysis of the ISCHIA Study.

Author

Toyoda M, Murata T, Hirota Y, Hosoda K, Kato K, Kouyama K, Kouyama R, Kuroda A, Matoba Y, Matsuhisa M, Meguro S, Miura J, Nishimura K, Shimada A, Suzuki S, Tone A, and Sakane N

Subjects
Humans, Blood Glucose Self-Monitoring, Quality of Life, Glucose, Blood Glucose, Dermatitis, Contact
Abstract

Objective: We previously reported the mean average relative difference (MARD) of the sensor glucose (SG) of the first-generation FreeStyle Libre with the original algorithm, an intermittent scanning continuous glucose monitoring (isCGM) device, was 15.6% in the Effect of Intermittent-Scanning Continuous Glucose Monitoring to Glycemic Control Including Hypoglycemia and Quality of Life of Patients with Type 1 Diabetes Mellitus Study (ISCHIA Study). In the present study, we aimed to further analyze its accuracy in detail by conducting a post-hoc analysis of the study., Methods: The ISCHIA Study was a multicenter, randomized, cross-over trial to assess the efficacy of isCGM. The SG levels of isCGM and the measured capillary blood glucose (BG) levels of 91 participants were used for the analysis., Results: Bland-Altman analysis showed bias of -13.0 mg/dl when the SG levels were compared to the BG levels, however no proportional bias was observed ( r = 0.085). MARD of the participants without and with contact dermatitis were 15.0 ± 6.0% and 27.4 ± 21.4% ( P = 0.001), respectively., Conclusion: There was negative bias in the SG levels of isCGM compared to the BG levels. There is a possibility that the complication of the contact dermatitis during isCGM use may be related with deteriorated accuracy of the SG levels.

Published
2023

22. A Low-Frequency APOB p.(Pro955Ser) Variant Contributes to the Severity of/Variability in Familial Hypercholesterolemia.

Author

Hori M, Takahashi A, Hosoda K, Ogura M, and Harada-Shiba M

Subjects
Humans, Proprotein Convertase 9 genetics, Receptors, LDL genetics, Phenotype, Apolipoproteins B genetics, Mutation, Hyperlipoproteinemia Type II genetics, Hypercholesterolemia
Abstract

Context: Heterozygous familial hypercholesterolemia (HeFH) is caused by a rare pathogenic variant in the LDLR, APOB, and PCSK9 genes. However, the causative variants in these genes have not been identified in approximately 40% of HeFH patients., Objective: Our aim was to identify novel (or additional) genes/variants that contribute to HeFH., Methods: Whole-exome sequencing was performed for 215 family members from 122 families with HeFH without pathogenic variants in the LDLR or PCSK9 genes., Results: We could not find novel causative familial hypercholesterolemia (FH) genes/variants by family analysis. Next, we examined all APOB variants. Twenty-four nonsynonymous APOB variants were identified. The allele frequencies of the c.2863C > T:p.(Pro955Ser) variant in the HeFH probands and the general Japanese population were 0.15 and 0.034, respectively [odds ratio 4.9 (95% CI 3.4-7.1); P = 6.9 × 10-13]. The patients harboring the c.2863C > T:p.(Pro955Ser) variant accounted for 9.8% (n = 63) of unrelated patients with HeFH (n = 645). The penetrance of the c.2863C > T:p.(Pro955Ser) variant was low in the pedigree-based genetic analysis. In an in vitro assay, low-density lipoprotein (LDL) uptake from patients with the homozygous c.2863C > T:p.(Pro955Ser) variant was 44% of the LDL uptake from control subjects, and it was similar to that of the LDL uptake from patients with the known pathogenic heterozygous p.(Arg3527Gln) variant., Conclusions: The low-frequency APOB c.2863C > T:p.(Pro955Ser) variant is not an FH-causative variant, but it has a moderate effect size in HeFH. These findings suggest that the combination of the APOB c.2863C > T:p.(Pro955Ser) variant and age, environmental factors, or other genetic factors contributes to the severity of or variability in the HeFH phenotype., (© The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)

Published
2023
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23. Assessment of the accuracy of an intermittent-scanning continuous glucose monitoring device in patients with type 2 diabetes mellitus undergoing hemodialysis (AIDT2H) study.

Author

Toyoda M, Murata T, Saito N, Kimura M, Takahashi H, Ishida N, Kitamura M, Hida M, Hayashi A, Moriguchi I, Kobayashi N, Tsuriya D, Sakao Y, Matsushita T, Ito Y, Suzuki S, Kasama S, Kasahara M, Yamakawa T, Mori K, Kuroda A, Miura J, Hirota Y, Abe M, Fukagawa M, Sakane N, and Hosoda K

Subjects
Aged, Female, Humans, Male, Prospective Studies, Reproducibility of Results, Blood Glucose Self-Monitoring instrumentation, Blood Glucose Self-Monitoring methods, Diabetes Mellitus, Type 2 blood, Renal Dialysis
Abstract

FreeStyle Libre has been approved for use in patients undergoing hemodialysis (HD) in Japan, unlike Europe and the United States; however, evidence regarding its accuracy in such patients is sparse. Forty-one participants with type 2 diabetes undergoing HD were recruited. The overall mean absolute relative difference and mean absolute difference were 23.4% and 33.9 mg/dL, respectively. Sensor glucose levels and capillary glucose levels were significantly correlated (r = 0.858, P < .01), although the sensor glucose levels were significantly lower than the capillary glucose levels. The accuracy of FreeStyle Libre in patients undergoing HD became deteriorated with the days of usage. The percentage of sensor results in Zones A and B in the consensus error grid analysis and in the Clarke error grid analysis were 99.7% and 99.0%, respectively. Its insufficient accuracy necessitates adjunct usage of FreeStyle Libre with self-monitoring of blood glucose in patients undergoing HD., (© 2021 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy.)

Published
2021
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