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120 results on '"Hsia, Ning-Yi"'

5. Taiwan ocular inflammation society consensus recommendations for the management of juvenile idiopathic arthritis-associated uveitis

Author

Chen, Wei-Dar, primary, Wu, Cheng-Hsiu, additional, Wu, Po-Yi, additional, Lin, Chang-Ping, additional, Ou, Liang-Shiou, additional, Hwang, De-Kuang, additional, Sheu, Shwu-Jiuan, additional, Chiang, Wei-Yu, additional, Chang, Yo-Chen, additional, Lin, Chun-Ju, additional, Chan, Wei-Chun, additional, Fang, Yueh-Fu, additional, Chien-Chieh Huang, Jerry, additional, Kao, Tzu-En, additional, Chiu, Fang-Yi, additional, Hsia, Ning-Yi, additional, and Hwang, Yih-Shiou, additional

Published
2024
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11. Prevalence of uveitis in syphilis patients in Taiwan

Author

Chen, Chia-Yun, primary, Kuo, Hou-Ting, additional, Hsu, Alan Y., additional, Lin, Chun-Ju, additional, Hsia, Ning-Yi, additional, Tien, Peng-Tai, additional, Lai, Chun-Ting, additional, Chen, Huan-Sheng, additional, and Tsai, Yi-Yu, additional

Published
2023
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12. Assessing Uveitis Risk following Pediatric Down Syndrome Diagnosis: A TriNetX Database Study.

Author

Hsu, Alan Y., Wang, Yu-Hsun, Lin, Chun-Ju, Li, You-Ling, Hsia, Ning-Yi, Lai, Chun-Ting, Kuo, Hou-Ting, Chen, Huan-Sheng, Tsai, Yi-Yu, and Wei, James Cheng-Chung

Subjects
IRIDOCYCLITIS, SYNDROMES in children, UVEITIS, DOWN syndrome, DATABASES, PEOPLE with Down syndrome
Abstract

Background and Objectives: The risks of uveitis development among pediatric patients with Down syndrome (DS) remain unclear. Therefore, we aimed to determine the risk of uveitis following a diagnosis of DS. Materials and Methods: This multi-institutional retrospective cohort study utilized the TriNetX database to identify individuals aged 18 years and younger with and without a diagnosis of DS between 1 January 2000 and 31 December 2023. The non-DS cohort consisted of randomly selected control patients matched by selected variables. This included gender, age, ethnicity, and certain comorbidities. The main outcome is the incidence of new-onset uveitis. Statistical analysis of the uveitis risk was reported using hazard ratios (HRs) and 95% confidence intervals (CIs). Separate analyses of the uveitis risk among DS patients based on age groups and gender were also performed. Results: A total of 53,993 individuals with DS (46.83% female, 58.26% white, mean age at index 5.21 ± 5.76 years) and 53,993 non-DS individuals (45.56% female, 58.28% white, mean age at index 5.21 ± 5.76 years) were recruited from the TriNetX database. Our analysis also showed no overall increased risk of uveitis among DS patients (HR: 1.33 [CI: 0.89–1.99]) compared to the non-DS cohort across the 23-year study period. Subgroup analyses based on different age groups showed that those aged 0–1 year (HR: 1.36 [CI: 0.68–2.72]), 0–5 years (HR: 1.34 [CI: 0.75–2.39]), and 6–18 years (HR: 1.15 [CI: 0.67–1.96]) were found to have no association with uveitis risk compared to their respective non-DS comparators. There was also no increased risk of uveitis among females (HR: 1.49 [CI: 0.87–2.56]) or males (HR: 0.82 [CI: 0.48–1.41]) with DS compared to their respective non-DS comparators. Conclusions: Our study found no overall increased risk of uveitis following a diagnosis of DS compared to a matched control population. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Optical Coherence Tomography Biomarkers in Predicting Treatment Outcomes of Diabetic Macular Edema after Ranibizumab Injections

Author

Chang, Yen-Chieh, primary, Huang, Yu-Te, additional, Hsu, Alan Y., additional, Meng, Ping-Ping, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Chen, Huan-Sheng, additional, Tien, Peng-Tai, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2023
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20. Tinnitus as a Potential Risk Factor for Uveitis: A 14-Year Nationwide Population-Based Cohort Study in Taiwan

Author

Chen, Yi-Jye, Hsu, Alan Y., Lin, Chun-Ju, Hsia, Ning-Yi, Meng, Ping-Ping, Liao, Pei-Lun, Hsu, Min-Yen, Tien, Peng-Tai, Lai, Chun-Ting, Chen, Huan-Sheng, Chiang, Chun-Chi, and Tsai, Yi-Yu

Abstract

Tinnitus and uveitis have shared commonality in pathophysiology in terms of autoimmunity. However, no studies that have linked any association between the conditions of tinnitus and uveitis. This is a retrospective study conducted from the Taiwan National Health Insurance database in order to investigate whether tinnitus patients are at increased risk of uveitis. Patients newly diagnosed with tinnitus between 2001 and 2014 were recruited and followed up until 2018. The endpoint of interest was a diagnosis of uveitis. A total of 31,034 tinnitus patients and 124,136 matched comparisons were analyzed. Tinnitus patients were found to have a significantly higher cumulative incidence for uveitis than those without the diagnosis of tinnitus with incidence rate of 1.68 (95% CI 1.55–1.82) per 10 000 person-months for tinnitus group and 1.48 (95% CI 1.42–1.54) per 10 000 person-months for non-tinnitus group. Tinnitus patients were found to have increased risk of developing uveitis.

Published
2023
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21. Short-Term Effects of Brolucizumab in the Treatment of Wet Age-Related Macular Degeneration or Polypoidal Choroidopathy Refractory to Previous Anti-Vascular Endothelial Growth Factor Therapy

Author

Hsu, Alan Y., primary, Lin, Chih-Ying, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Lin, Jane-Ming, additional, Tien, Peng-Tai, additional, Meng, Ping-Ping, additional, Ku, Wei-Ning, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2022
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24. Changes of Estimated Glomerular Filtration Rate and Glycated Hemoglobin A1c in Diabetic Macular Edema Patients Treated by Ranibizumab and Aflibercept in the Tertiary Referral Hospital

Author

Ku, Wei-Ning, primary, Tien, Peng-Tai, additional, Lin, Chun-Ju, additional, Chiang, Chun-Chi, additional, Hsia, Ning-Yi, additional, Lai, Chun-Ting, additional, Muo, Chih-Hsin, additional, Bair, Henry, additional, Chen, Huan-Sheng, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2022
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27. Optical Coherence Tomography Biomarkers in Predicting Treatment Outcomes of Diabetic Macular Edema After Dexamethasone Implants

Author

Huang, Yu-Te, primary, Chang, Yen-Chieh, additional, Meng, Ping-Ping, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Chen, Huan-Sheng, additional, Tien, Peng-Tai, additional, Bair, Henry, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2022
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31. Comparison of Choroidal Thickness, Foveal Avascular Zone, and Macular Capillary Density in Macular Edema Secondary to Branch Retinal Vein Occlusion Treated with Ranibizumab or Aflibercept—A Prospective Study

Author

Huang, Yu-Te, primary, Wang, I, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Chen, Huan-Sheng, additional, Tien, Peng-Tai, additional, Bair, Henry, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, Chen, Chang-He, additional, Wu, Wen-Chuan, additional, and Tsai, Yi-Yu, additional

Published
2022
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34. Clinical Manifestations and Outcomes of Tubercular Uveitis in Taiwan—A Ten-Year Multicenter Retrospective Study

Author

Lin, Chun-Ju, primary, Hsia, Ning-Yi, additional, Hwang, De-Kuang, additional, Hwang, Yih-Shiou, additional, Chang, Yo-Chen, additional, Lee, Yueh-Chang, additional, Hsu, Yung-Ray, additional, Yeh, Po-Ting, additional, Lin, Chang-Ping, additional, Chen, Hsi-Fu, additional, Jan, Wei-Chun, additional, Chiang, Wei-Yu, additional, and Tsai, Ming-Ling, additional

Published
2022
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35. The incidence of uveitis after systemic lymphoma in Taiwan

Author

Huang, Yu-Te, primary, Lin, Chun-Ju, additional, Liao, Pei-Lun, additional, Hsu, Min-Yen, additional, Chang, Cheng-Hsien, additional, Tien, Peng-Tai, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Bair, Henry, additional, Chen, Huan-Sheng, additional, Chiang, Chun-Chi, additional, and Tsai, Yi-Yu, additional

Published
2022
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42. Chronic Kidney Disease as A Potential Risk Factor for Uveitis: A 13-Year Nationwide Population-Based Cohort Study in Taiwan.

Author

Lin, Chun-Ju, Tien, Peng-Tai, Lai, Chun-Ting, Hsia, Ning-Yi, Chang, Cheng-Hsien, Bair, Henry, Chen, Huan-Sheng, Yang, Yu-Cih, Lin, Jan-Ming, Chen, Wen-Lu, and Tsai, Yi-Yu

Subjects
DISEASE risk factors, IRIDOCYCLITIS, UVEITIS
Abstract

To investigate whether patients with chronic kidney disease (CKD) are at increased risk of uveitis. Data was collected from the Taiwan National Health Insurance system and included patients newly diagnosed with CKD between 2000 and 2012. The endpoint of interest was a diagnosis of uveitis. 30,256 CKD patients and 121,024 matched comparisons were analyzed. CKD patients were found to have a significantly higher cumulative uveitis incidence. Through multivariate Cox regression analysis, the CKD group was found to have higher risk of developing uveitis (adjusted hazard ratio 1.51). After stratified by gender, age, and comorbidities (hypertension, diabetes, and hyperlipidemia), the increased risk of uveitis in CKD patients remained significant. Patients with CKD were found to have higher risk of developing uveitis. For patients over 18 years old and with hypertension, diabetes, or hyperlipidemia, the presence of CKD was demonstrated as an additional crucial factor for uveitis development. [ABSTRACT FROM AUTHOR]

Published
2022
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44. Astigmatism Management with Astigmatism-Correcting Intraocular Lens Using Two Toric Calculators – A Comparative Case Series

Author

Huang, Yu-Te, primary, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Tien, Peng-Tai, additional, Bair, Henry, additional, Chen, Huan-Sheng, additional, Chiang, Chun-Chi, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, Wu, Wen-Chuan, additional, and Tsai, Yi-Yu, additional

Published
2021
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45. Relationship between Uveitis and Thyroid Disease: A 13-Year Nationwide Population-based Cohort Study in Taiwan.

Author

Lin, Chun-Ju, Tien, Peng-Tai, Chang, Cheng-Hsien, Hsia, Ning-Yi, Yang, Yu-Cih, Lai, Chun-Ting, Bair, Henry, Chen, Huan-Sheng, Tsai, Yi-Yu, and Chang, Cheng-Hsien MD, PhD

Subjects
THYROID diseases, UVEITIS, NATIONAL health insurance, COHORT analysis, AGE groups, DATABASES, RETROSPECTIVE studies, DISEASE incidence, NATIONAL health services, LONGITUDINAL method
Abstract

Purpose: To investigate whether patients with thyroid disease are at increased risk of uveitis.Methods: Data was collected from the Taiwan National Health Insurance system and included patients newly diagnosed with thyroid disease from 2000 to 2012. The endpoint of interest was a diagnosis of uveitis.Results: In analyzing 21,396 patients with thyroid disease, yielding 85,584 matched comparisons, patients with thyroid disease to have a significantly higher cumulative incidence of uveitis when compared to the control cohort with the Kaplan-Meier analysis. This result was further confirmed by Cox regression analysis. The increased risk was persistent in both genders. The association between thyroid disease and uveitis was stronger in patients without diabetes or hypertension.Conclusion: Patients with thyroid disease were found to have a higher risk for uveitis. For certain age groups or patients without diabetes or hypertension, the role of thyroid disease might be more crucial for uveitis development. [ABSTRACT FROM AUTHOR]

Published
2021
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46. Significant improvement of ocular clinical pictures of iris metastasis from small-cell lung cancer after systemic chemotherapy.

Author

Huang, Li-Ying, Hsia, Ning-Yi, Lai, Chun-Ting, Tien, Peng-Tai, Lin, Chun-Ju, Lin, Jane-Ming, Tsai, Yi-Yu, and Chen, Wen-Lu

Abstract

The uveal tract is the most common ophthalmic site of ocular metastasis from systemic tumors due to the luxurious blood flow within the choroidal tissue. However, iris metastasis from systemic cancer is uncommon, accounting for only 8% of cases of uveal metastasis. There are several methods for the treatment of iris tumor. Here, we reported a case of iris metastasis from small-cell lung cancer. The tumor shrunk after systemic treatment for lung cancer and showed no recurrence after a 4-month follow-up. [ABSTRACT FROM AUTHOR]

Published
2021
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48. The Significant Contribution of Interleukin-16 Genotypes, Smoking, Alcohol Drinking, and Helicobacter Pylori Infection to Gastric Cancer.

Author

Fu CK, Mong MC, Tzeng HE, Yang MD, Chen JC, Hsia TC, Hsia NY, Tsai CW, Chang WS, Chen CP, and Bau DT

Subjects
Humans, Alcohol Drinking adverse effects, Case-Control Studies, Genetic Predisposition to Disease, Genotype, Interleukin-16 genetics, Polymorphism, Single Nucleotide, Risk Factors, Smoking adverse effects, Helicobacter Infections complications, Helicobacter Infections genetics, Helicobacter pylori, Stomach Neoplasms genetics, Stomach Neoplasms complications
Abstract

Background/aim: Elevated serum interleukin-16 (IL-16) levels have been reported in gastric cancer (GC) tissues; however, the role of IL-16 genotypes in GC susceptibility remains largely unexplored. This study aimed to investigate the contribution of IL-16 genotypes to GC susceptibility and to assess their interactions with smoking, alcohol drinking, and Helicobacter pylori (H. pylori) infection., Materials and Methods: Polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) methodology was employed to determine IL-16 rs4778889, rs11556218, and rs4072111 genotypic characteristics in 161 patients with GC and 483 controls., Results: Significant differences were observed in the distribution of genotypic (p=0.0009) and allelic (p=0.0002) frequencies of IL-16 rs11556218 among cases and controls. Specifically, the frequencies of TG and GG genotypes of IL-16 rs11556218 were 37.3% and 6.8% among patients with GC, respectively, which were higher than those among the controls (26.7% and 2.7%). In contrast, no significant differences were found concerning IL-16 rs4778889 or rs4072111. Notably, individuals with IL-16 rs11556218 TT genotypes exhibited significant protective effects against GC when exposed to risk factors, such as smoking, alcohol drinking, and H. pylori infection., Conclusion: IL-16 rs11556218 T allele was associated with reduced susceptibility to GC. Furthermore, carriers of the TT genotype showed protection against GC risk factors, including smoking, alcohol drinking, and H. pylori infection. These findings provide valuable insights into the potential role of IL-16 genotypes in GC development and their interactions with lifestyle and infectious factors., (Copyright © 2024, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)

Published
2024
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49. Tinnitus as a Potential Risk Factor for Uveitis: A 14-Year Nationwide Population-Based Cohort Study in Taiwan.

Author

Chen YJ, Hsu AY, Lin CJ, Hsia NY, Meng PP, Liao PL, Hsu MY, Tien PT, Lai CT, Chen HS, Chiang CC, and Tsai YY

Abstract

Background: Tinnitus and uveitis have shared commonality in pathophysiology in terms of autoimmunity. However, no studies that have linked any association between the conditions of tinnitus and uveitis., Methods: This is a retrospective study conducted from the Taiwan National Health Insurance database in order to investigate whether tinnitus patients are at increased risk of uveitis. Patients newly diagnosed with tinnitus between 2001 and 2014 were recruited and followed up until 2018. The endpoint of interest was a diagnosis of uveitis., Results: A total of 31,034 tinnitus patients and 124,136 matched comparisons were analyzed. Tinnitus patients were found to have a significantly higher cumulative incidence for uveitis than those without the diagnosis of tinnitus with incidence rate of 1.68 (95% CI 1.55-1.82) per 10 000 person-months for tinnitus group and 1.48 (95% CI 1.42-1.54) per 10 000 person-months for non-tinnitus group., Conclusion: Tinnitus patients were found to have increased risk of developing uveitis.

Published
2023
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50. Temporal and double inverted internal limiting membrane flap for bilateral choroidal ruptures complicated by bilateral macular holes.

Author

Huang LY, Lin CJ, Lai CT, Hsia NY, Bair H, Tien PT, Chen WL, Lin JM, Chiang CC, and Tsai YY

Abstract

Choroidal ruptures occur in 5% to 10% closed-globe injuries with wide variation in visual prognosis, which depending on the visual acuity at presentation, the location of the rupture, and other associated ocular injuries. We reported a case of bilateral traumatic choroidal rupture with a large macular hole. We performed surgery in the right eye of microincisional vitrectomy, temporally inverted internal limiting membrane (ILM) flap, and C3F8 tamponade; then microincisional vitrectomy, fibrotic scar removal, double inverted ILM flap, and C3F8 tamponade in the left eye. After surgery, she achieved both good anatomical and visual acuity improvement in the right eye, but limited visual acuity improvement in the left eye due to subfoveal choroidal scar formation., Competing Interests: The authors declare that there are no conflicts of interests of this paper., (Copyright: © 2022 Taiwan J Ophthalmol.)

Published
2022
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