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Biomimetic oxidation of primary amines to carboxylic acids has been developed where the copper-containing amine oxidase (CuAO)-like o-NQ-catalyzed aerobic oxidation was combined with the aldehyde dehydrogenase (ALDH)-like TBHP-mediated imine oxidation protocol. Notably, the current tandem oxidation strategy provides a new mechanistic insight into the imine intermediate and the seemingly simple TBHP-mediated oxidation pathways of imines. The developed metal-free amine oxidation protocol allows the use of molecular oxygen and TBHP, safe forms of oxidant that may appeal to the industrial application.

A photocatalyst-free visible-light-induced selenofunctionalization of alkenes has been developed using a variety of nucleophiles. The homolytic scission of diselenides under visible-light conditions coupled with the aerobic selenol oxidation to diselenides allowed the successful implementation of three-component selenofunctionalization under visible-light irradiation in open-air conditions. The mechanistic studies revealed the critical role of oxygen content in a reaction medium, where the electron transfer process from the carbon-based radicals to either molecular oxygen or selenyl radicals was controlled.

A biomimetic alcohol dehydrogenase (ADH)-like oxidation protocol was developed using an

A catalytic asymmetric desymmetrization of cyclohexadienones was accomplished via Van Leusen pyrrole synthesis in the presence of a chiral silver catalyst. The ready access to chiral-fused pyrrole derivatives is attributed to the identification of a suitable isocyanomethyl sulfone surrogate, NasMIC. The current Ag(I)-chiral phosphino-carboamide ligand system can be extended to the kinetic resolution of racemic cyclohexadienones, capitalizing on the differentiated reactivity of chiral quaternary complexes from AgSbF

The on-board tilting mirror calibration mechanism has a mechanical driving part that helps to achieve the main functional modes of deployment and stow when calibrating a spaceborne imaging sensor. In general, it is necessary to consider a holding and release device in the mechanism design, to secure the structural safety of the mechanical driving part in severe launch environments. However, in the present study, we proposed a novel design strategy based on mass balancing, to guarantee mechanical safety on the driving part of the tilt mirror mechanism, although the implementation of the holding and release mechanism was not considered in the design. The effectiveness of the proposed design was experimentally verified via launch vibration and life cycle tests. The test results demonstrated that the mechanism fulfills all the required functions, and the design approach proposed in this study is effective for ensuring mechanical safety on the driving part of the tilting mirror mechanism in severe launch vibration environments.