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9 results on '"Ikeoka, Kuniyasu"'

3. Impact of a Cancer History on Cardiovascular Events Among Patients With Myocardial Infarction Who Received Revascularization

Author

Takeuchi, Taro, primary, Kosugi, Shumpei, additional, Ueda, Yasunori, additional, Ikeoka, Kuniyasu, additional, Yamane, Haruya, additional, Takayasu, Kohtaro, additional, Ohashi, Takuya, additional, Fukushima, Takashi, additional, Horiuchi, Kohei, additional, Iehara, Takashi, additional, Sakamoto, Mai, additional, Ukai, Kazuho, additional, Minami, Shinya, additional, Mizumori, Yuuki, additional, Muraoka, Naoya, additional, Nakamura, Masayuki, additional, Ozaki, Tatsuhisa, additional, Mishima, Tsuyoshi, additional, Abe, Haruhiko, additional, Inoue, Koichi, additional, and Matsumura, Yasushi, additional

Published
2023
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5. Temporary Rise in Blood Thrombogenicity in Patients with Acute Myocardial Infarction

Author

Kosugi, Shumpei, Ueda, Yasunori, Abe, Haruhiko, Ikeoka, Kuniyasu, Mishima, Tsuyoshi, Ozaki, Tatsuhisa, Takayasu, Kohtaro, Ohashi, Takuya, Yamane, Haruya, Nakamura, Masayuki, Fukushima, Takashi, Horiuchi, Kohei, Iehara, Takashi, Osaki, Satoshi, Ozato, Kazuki, Inoue, Koichi, Koretsune, Yukihiro, and Matsumura, Yasushi

Subjects
Economics and Econometrics, t-tas, blood thrombogenicity, RC666-701, Materials Chemistry, Media Technology, acute myocardial infarction, Diseases of the circulatory (Cardiovascular) system, Original Article, Forestry, coronary artery disease
Abstract

Objective Although blood thrombogenicity seems to be one of the determinant factors for the development of acute myocardial infarction (MI), it has not been dealt with in-depth. This study aimed to investigate blood thrombogenicity and its change in acute MI patients. Methods and Results We designed a prospective, observational study that included 51 acute MI patients and 83 stable coronary artery disease (CAD) patients who underwent cardiac catheterization, comparing thrombogenicity of the whole blood between: (1) acute MI patients and stable CAD patients; and (2) acute and chronic phase in MI patients. Blood thrombogenicity was evaluated by the Total Thrombus-Formation Analysis System (T-TAS) using the area under the flow pressure curve (AUC30) for the AR-chip. Acute MI patients had significantly higher AUC30 than stable CAD patients (median [interquartile range], 1,771 [1,585–1,884] vs. 1,677 [1,527–1,756], p = 0.010). Multivariate regression analysis identified acute MI with initial TIMI flow grade 0/1 as an independent determinant of high AUC30 (β = 0.211, p = 0.013). In acute MI patients, AUC30 decreased significantly from acute to chronic phase (1,859 [1,550–2,008] to 1,521 [1,328–1,745], p = 0.001). Conclusion Blood thrombogenicity was significantly higher in acute MI patients than in stable CAD patients. Acute MI with initial TIMI flow grade 0/1 was significantly associated with high blood thrombogenicity by multivariate analysis. In acute MI patients, blood thrombogenicity was temporarily higher in acute phase than in chronic phase.

Published
2022

6. Temporary Rise in Blood Thrombogenicity in Patients with Acute Myocardial Infarction

Author

Kosugi, Shumpei, additional, Ueda, Yasunori, additional, Abe, Haruhiko, additional, Ikeoka, Kuniyasu, additional, Mishima, Tsuyoshi, additional, Ozaki, Tatsuhisa, additional, Takayasu, Kohtaro, additional, Ohashi, Takuya, additional, Yamane, Haruya, additional, Nakamura, Masayuki, additional, Fukushima, Takashi, additional, Horiuchi, Kohei, additional, Iehara, Takashi, additional, Osaki, Satoshi, additional, Ozato, Kazuki, additional, Inoue, Koichi, additional, Koretsune, Yukihiro, additional, and Matsumura, Yasushi, additional

Published
2021
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9. Impact of a Cancer History on Cardiovascular Events Among Patients With Myocardial Infarction Who Received Revascularization.

Author

Takeuchi T, Kosugi S, Ueda Y, Ikeoka K, Yamane H, Takayasu K, Ohashi T, Fukushima T, Horiuchi K, Iehara T, Sakamoto M, Ukai K, Minami S, Mizumori Y, Muraoka N, Nakamura M, Ozaki T, Mishima T, Abe H, Inoue K, and Matsumura Y

Subjects
Humans, Retrospective Studies, Aftercare, Patient Discharge, Coronary Angiography, Treatment Outcome, Risk Factors, Myocardial Revascularization methods, Myocardial Infarction etiology, Percutaneous Coronary Intervention adverse effects, Neoplasms etiology
Abstract

Background: It remains controversial whether a cancer history increases the risk of cardiovascular (CV) events among patients with myocardial infarction (MI) who undergo revascularization.Methods and Results: Patients who were confirmed as type 1 acute MI (AMI) by coronary angiography were retrospectively analyzed. Patients who died in hospital or those not undergoing revascularization were excluded. Patients with a cancer history were compared with those without it. A cancer history was examined in the in-hospital cancer registry. The primary outcome was a composite of cardiac death, recurrent type 1 MI, post-discharge coronary revascularization, heart failure hospitalization, and stroke. Among 551 AMI patients, 55 had a cancer history (cancer group) and 496 did not (non-cancer group). Cox proportional hazards model revealed that the risk of composite endpoint was significantly higher in the cancer group than in the non-cancer group (adjusted hazard ratio [HR]: 1.78; 95% confidence interval [CI]: 1.13-2.82). Among the cancer group, patients who were diagnosed as AMI within 6 months after the cancer diagnosis had a higher risk of the composite endpoint than those who were diagnosed as AMI 6 months or later after the cancer diagnosis (adjusted HR: 5.43; 95% CI: 1.55-19.07)., Conclusions: A cancer history increased the risk of CV events after discharge among AMI patients after revascularization.

Published
2024
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