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Innovative fluorescence materials combining the special reagent stimuli response have considerable potential to provide a convenient and highly secure communication strategy for encoding messages. With the unique decryption method, encrypted information that is previously unidentifiable can now be accurately parsed without the risk of interception or decipherment. Herein, white‐emitting light semiconducting polymer dots for advanced secret communication are developed, along with a machine learning‐based encryption‐decryption strategy. The encrypted data are readily hidden by the fluorescent polymer‐stimulus system, which can be identified by fluorescence imaging equipment and only be decrypted via the special linear discriminant analysis route pre‐transferred to the recipient. The results presented here suggest that chemical‐stimulated fluorescence information storage and the unique decoding strategy can be developed as prospective methods for advanced data communication and security protection. [ABSTRACT FROM AUTHOR]

Aβ oligomers have been widely accepted as significant biomarkers for Alzheimer's disease (AD) detection, monitoring, and therapy since they are highly correlated with AD development. In this work, an electrochemical array-based sensing platform was successfully built using a group of functionalized graphene with different physicochemical features. Since the electro-insulated Aβ peptide species severely interfered with the electron transport on the electrode surface, the presence of Aβ led to a significant change in the electrochemical impedance signal. The resulting variety of the impedance was then classified and processed by linear discriminant analysis. The constructed sensing platform can discriminate different Aβ forms, the mixture of various Aβ forms, and different ratios of Aβ42 to Aβ40 with 100% accuracy by only the combination of dual probes. Furthermore, it also exhibited excellent performance for screening Aβ inhibitors and metal chelators. The strategy utilizes the infinitesimal general discrepancy instead of specific biomarker recognition, exhibiting the advantage of no requirement to know the exact information about the specific ligand and receptor in advance, which is promising to be widened for the other biosensing detection fields. • A facile functionalized graphene-based electrochemical array sensor was successfully constructed. • The prepared sensing platform could discriminate different Aβ forms, the mixture of various Aβ forms, and different ratios of Aβ42 to Aβ40 in buffered solutions as well as in complex body fluid environments. • 100% identification through the combination of dual probes was achieved, indicating the super diagnostic capacity of the sensor array. • The strategy utilizes the infinitesimal general discrepancy instead of specific biomarker recognition. [ABSTRACT FROM AUTHOR]

The biofilm resistance of microorganisms has severe economic and environmental implications, especially the contamination of facilities associated with human life, including medical implants, air-conditioning systems, water supply systems, and food-processing equipment, resulting in the prevalence of infectious diseases. Once bacteria form biofilms, their antibiotic resistance can increase by 10–1,000-fold, posing a great challenge to the treatment of related diseases. In order to overcome the contamination of bacterial biofilm, destroying the biofilm's matrix so as to solve the penetration depth dilemma of antibacterial agents is the most effective way. Here, a magnetically controlled multifunctional micromotor was developed by using H 2 O 2 as the fuel and MnO 2 as the catalyst to treat bacterial biofilm infection. In the presence of H 2 O 2 , the as-prepared motors could be self-propelled by the generated oxygen microbubbles. Thereby, the remotely controlled motors could drill into the EPS of biofilm and disrupt them completely with the help of bubbles. Finally, the generated highly toxic •OH could efficiently kill the unprotected bacteria. This strategy combined the mechanical damage, highly toxic •OH, and precise magnetic guidance in one system, which could effectively eliminate biologically infectious fouling in microchannels within 10 min, possessing a wide range of practical application prospects especially in large scale and complex infection sites. [Display omitted] • Mechanical damage, highly toxic •OH, and precise magnetic guidance were integrated in one antimicrobial system. • H 2 O 2 was used as the fuel to trigger the high-speed movement of motor and serve as the source of high toxic •OH. • Enhanced antibacterial activities were obtained even for the treatment of drug-resistant bacteria MRSA. • The micro-nano hybrid multifunctional motors developed here are precisely controlled and deeply penetrated. • Motors have strong destructive ability for the treatment of large-scale biofilm EPS even at complex infection sites. [ABSTRACT FROM AUTHOR]

• The persistent luminescent material exhibits robust optical performance in the healthcare field. • Various testing and therapeutic techniques have been developed by integrating the unique long afterglow properties. • Increased efforts have been made to improve the brightness and durability of the new material. • PLM-based techniques are promising to solve more public health problems in various scenarios. With the advancement of human civilization and the growing diversity and multipolarity of the international community, there is a mounting emphasis on addressing public health and safety concerns. In order to respond to public safety incidents, the development of in-situ, timely, and sensitive detection methods has become the key. The pursuit of a high quality of life has revolutionized the investigation and evaluation of epidemics, tumors, and endemic diseases, necessitating tracing based on unique genetic sequences or antigenic properties of pathogenic microorganisms, tumor markers, and bioactive molecules. Additionally, the prevalence of food safety incidents has fostered societal expectations for continuous assurance through the detection of pesticide and bio-enzyme residues, environmental and industrial pollutants, as well as monitoring hazardous substances in food production. Due to its unique optical phenomenon and persistent afterglow emissions following stimulation cessation, persistent luminescent materials (PLMs) have garnered increased research attention across various sectors. The ability to quench in situ excitation and retain energy for extended durations has positioned them as an appealing system for implementation in luminescence imaging and sensing applications pertaining to public health and safety. This review aims to provide a comprehensive overview of groundbreaking work conducted over the past five years in the field of PLMs in relation to public health. We first highlight the luminescence principles of PLMs. In the following parts, we provide comprehensive coverage of the latest advancements and trends in the application of PLMs as biosensors in clinical examination and food contaminant analysis. Moreover, we emphasize their advantages in the application of antimicrobial treatment and light-guided tumor treatment. Finally, we discuss the future research directions and challenges in developing of PLMs for public health. [ABSTRACT FROM AUTHOR]

The use of Formic acid as an alternative to fossil fuels is promising, both from economical and ecological standpoints, and has received great of attention owing to its inherently superiority in recent decades. Nevertheless, efficient and low-cost solid catalyst for formic acid dehydrogenation at room temperature still constitutes a biggish challenge. Moreover, comparing to increase the catalytic performance of catalysts, very little attention payed to the kinetic mechanism of dehydrogenation reaction because of the lack of effective characterization artifice. Here, the as-prepared Ni@Pd nanoparticles by a sequential reduction process can be useful catalyst for formic acid decomposition at room temperature without a promoter. Thanks to the effective catalyst and isotope distribution technique, preliminary mechanistic results firstly reveal that hydrogen is obtained via a H-atom recombination on isolated sites after the proton exchange randomly between activated H and solvent. • The catalyst shows the enhanced formic acid dehydrogenation performance (645 h−1). • The Ni-core helps to increase the activity and CO resistance of Pd a lot. • Compare to pure Pd NCs, the cost of catalyst is greatly reduced. • Activated H exchange with water was firstly revealed by isotope substitution design. [ABSTRACT FROM AUTHOR]

We summarized the recent advances of functional MOFs- and COFs-based efficient sensing platforms developed for the measurement of foodborne contaminants. [Display omitted] • The harms of food-borne contaminants to human society are reviewed. • Brief introduction of metal–organic frameworks (MOFs) and covalent organic frameworks was concluded. • Recent advances for the detection foodborne organic contaminants based on MOFs and COFs were summarized. • Future challenges in the actual application and insights into the future directions in this promising field was discussed. Foodborne organic contaminants against health, mainly including antibiotics, pesticides, mycotoxins, foodborne bacteria, etc., have been considered one of the global public health problems. The early detection of these organic contaminants before consumption can significantly reduce the risk of acute or chronic food poisoning. Therefore, it's of great significance to develop effective sensing strategies for convenient, rapid, sensitive, and selective food quality monitoring. Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), as highly promising porous materials with multifunctionality, exhibit broad prospects in the field of chemical or biological sensing. They possess great potential to meet the requirements for detecting numerous analytes. Here, we summarized the recent advances of functional MOFs- and COFs-based efficient sensing platforms developed for the measurement of foodborne contaminants. In addition, a brief discussion of the future challenges in the practical application of these platforms and insights into the future directions in this promising field was also included. [ABSTRACT FROM AUTHOR]

Water pollution caused by harmful heavy metal ions (HMIs) can significantly impact aquatic ecosystems and pose a high risk to human health. In this work, equipped with ultra-high fluorescence brightness, efficient energy transfer, and environmentally friendly performance, polymer dots (Pdots) were employed to construct a pattern recognition fluorescent HMIs detection platform. A single-channel unary Pdots differential sensing array was first developed to identify multiple HMIs with 100% classification accuracy. Then an "all-in-one" multiple Förster resonance energy transfer (FRET) Pdots differential sensing platform was constructed to discriminate HMIs in the artificial polluted water samples and actual water samples, exhibiting high classification accuracy in distinguishing HMIs. The proposed strategy leverages the compounded cumulative differential variation of diverse sensing channels for analytes, which is anticipated to find extensive applications in other fields for detection purposes. • The ultra-brightness and high stability of Pdots sensors render them highly promising for efficiently detecting heavy metal ions. • The preparation and detection process of Pdots-based sensors were facile and user-friendly. • The implementation of an "all-in-one" strategy simplified the process by consolidating multiple assays into a single one. • The streamlined detection process can effectively mitigate analytical errors arising from multiple experiments. [ABSTRACT FROM AUTHOR]

[Display omitted] • A comprehensive overview of smart singlet oxygen carriers for enhanced cancer photodynamic therapy is presented. • A summary of the traditional preparative strategies for the design and fabrication of singlet oxygen carriers is discussed. • A demonstration of the photodynamic therapy performance improved by naphthalenes, anthracenes, and pyridines-derived small molecules or polymers is systematically discussed in detail. • A brief outlook on the future research and development of singlet oxygen carriers is also articulated. Hypoxia is a significant feature of the tumor, which has been proved to be the major challenge in translating photodynamic therapy (PDT) into clinical applications. To solve this issue, singlet oxygen carriers have been used to relieve tumor hypoxia and accordingly improve the therapeutic effect of PDT. Herein, a systematic summary of recent progress in the design and preparation of singlet oxygen carriers to overcome the hypoxia issue and realize the enhanced PDT is presented. For discussing purpose, the typical molecular backbone applied for the design and fabrication of an intelligent singlet oxygen carrier is firstly discussed, with an emphasis on the mechanism interpretation of the reversible trap and release of singlet oxygen. Furthermore, the enhanced PDT realized by innovative singlet oxygen carriers is systematically discussed in detail, including therapeutic platforms based on naphthalenes, anthracenes, and pyridines-derived small molecules or polymers. Finally, some critical points for singlet oxygen carrier design and an outlook for the future research and development of this promising field are provided. We sincerely anticipate the information presented in this review to provide insightful design guidelines for the further development of precise and efficient antitumor application systems based on the singlet oxygen carrier. [ABSTRACT FROM AUTHOR]