1. Impact of exercise on pulmonary artery pressure in patients with heart failure using an ambulatory pulmonary artery pressure monitor
- Author
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Rola Khedraki, Jacob Abraham, Orvar Jonsson, Kunjan Bhatt, Hesham R. Omar, Mosi Bennett, Arvind Bhimaraj, Ashrith Guha, Patrick McCann, Evan D. Muse, Monique Robinson, Andrew J. Sauer, Andrew Cheng, Samantha Bagsic, Marat Fudim, J. Thomas Heywood, and Maya Guglin
- Subjects
CardioMEMS ,heart failure ,hemodynamics ,six minute walk test ,pulmonary pressures ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundIn this multicenter prospective study, we explored the relationship between pulmonary artery pressure (PAP) at rest and in response to a 6-min walk test (6MWT) in ambulatory patients with heart failure (HF) with an implantable PAP sensor (CardioMEMS, Abbott).MethodsBetween 5/2019 and 2/2021, HF patients with a CardioMEMS sensor were recruited from seven sites. PAP was recorded in the supine and seated position at rest and in the seated position immediately post-exercise.ResultsIn our cohort of 66 patients, mean age was 70 ± 12 years, 67% male, left ventricular ejection fraction (LVEF) 15 mmHg) demonstrated a greater increase in post-exercise PAP.ConclusionThe measurement of PAP with CardioMEMS is feasible immediately post-exercise. Despite being well-managed, patients had severely limited functional capacity. We observed a significant increase in PAP with ambulation which was greater in patients with higher baseline pressures.
- Published
- 2023
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