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Your search keyword '"Lasa, Marta"' showing total 14 results
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14 results on '"Lasa, Marta"'

1. Minimally Invasive Assessment of Peripheral Residual Disease During Maintenance or Observation in Transplant-Eligible Patients With Multiple Myeloma.

Author

Lasa, Marta, Notarfranchi, Laura, Agullo, Cristina, Gonzalez, Carmen, Castro, Sergio, Perez, Jose J., Burgos, Leire, Guerrero, Camila, Calasanz, Maria Jose, Flores-Montero, Juan, Oriol, Albert, Bargay, Joan, Rios, Rafael, Cabañas, Valentin, Cabrera, Carmen, Martinez-Martinez, Rafael, Encinas, Cristina, De Arriba, Felipe, Hernandez, Miguel-Teodoro, and Palomera, Luis

Published
2025
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2. A CD38/CD3xCD28 trispecific T‐cell engager as a potentially active agent in multiple myeloma patients relapsed and/or refractory to anti‐CD38 monoclonal antibodies.

Author

Zabaleta, Aintzane, Blanco, Laura, Kim, Peter S., Bisht, Kamlesh, Wang, Hongfang, Van de Velde, Helgi, Lasa, Marta, Tamariz‐Amador, Luis‐Esteban, Rodriguez‐Otero, Paula, San‐Miguel, Jesús, Paiva, Bruno, and Martín‐Sánchez, Esperanza

Subjects
CD38 antigen, KILLER cells, MULTIPLE myeloma, DISEASE relapse, MONOCLONAL antibodies
Abstract

Summary: There is accumulating evidence of BCMA and GPRC5D loss after treatment with T‐cell redirecting therapies in patients with relapsed/refractory multiple myeloma (RRMM). While complete CD38 loss is not observed upon relapses after treatment with anti‐CD38 monoclonal antibodies (mAb), there is downregulation of surface CD38 expression and decreased number and function of NK cells, which renders these patients resistant to retreatment with anti‐CD38 mAb. Here, we provide preclinical evidence that RRMM patients previously exposed to anti‐CD38 mAb could benefit from T‐cell‐based immunotherapy that depend less on CD38 antigen density and NK‐cell activity, such as the novel CD38/CD3xCD28 trispecific T‐cell engager, SAR442257. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Supplementary Figure 3 from The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma

Author

Moreno, Laura, primary, Perez, Cristina, primary, Zabaleta, Aintzane, primary, Manrique, Irene, primary, Alignani, Diego, primary, Ajona, Daniel, primary, Blanco, Laura, primary, Lasa, Marta, primary, Maiso, Patricia, primary, Rodriguez, Idoia, primary, Garate, Sonia, primary, Jelinek, Tomas, primary, Segura, Victor, primary, Moreno, Cristina, primary, Merino, Juana, primary, Rodriguez-Otero, Paula, primary, Panizo, Carlos, primary, Prosper, Felipe, primary, San-Miguel, Jesus F., primary, and Paiva, Bruno, primary

Published
2023
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5. Supplementary Figure 4 from The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma

Author

Moreno, Laura, primary, Perez, Cristina, primary, Zabaleta, Aintzane, primary, Manrique, Irene, primary, Alignani, Diego, primary, Ajona, Daniel, primary, Blanco, Laura, primary, Lasa, Marta, primary, Maiso, Patricia, primary, Rodriguez, Idoia, primary, Garate, Sonia, primary, Jelinek, Tomas, primary, Segura, Victor, primary, Moreno, Cristina, primary, Merino, Juana, primary, Rodriguez-Otero, Paula, primary, Panizo, Carlos, primary, Prosper, Felipe, primary, San-Miguel, Jesus F., primary, and Paiva, Bruno, primary

Published
2023
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6. Supplementary Figure 5 from The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma

Author

Moreno, Laura, primary, Perez, Cristina, primary, Zabaleta, Aintzane, primary, Manrique, Irene, primary, Alignani, Diego, primary, Ajona, Daniel, primary, Blanco, Laura, primary, Lasa, Marta, primary, Maiso, Patricia, primary, Rodriguez, Idoia, primary, Garate, Sonia, primary, Jelinek, Tomas, primary, Segura, Victor, primary, Moreno, Cristina, primary, Merino, Juana, primary, Rodriguez-Otero, Paula, primary, Panizo, Carlos, primary, Prosper, Felipe, primary, San-Miguel, Jesus F., primary, and Paiva, Bruno, primary

Published
2023
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7. Supplementary Figure 1 from The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma

Author

Moreno, Laura, primary, Perez, Cristina, primary, Zabaleta, Aintzane, primary, Manrique, Irene, primary, Alignani, Diego, primary, Ajona, Daniel, primary, Blanco, Laura, primary, Lasa, Marta, primary, Maiso, Patricia, primary, Rodriguez, Idoia, primary, Garate, Sonia, primary, Jelinek, Tomas, primary, Segura, Victor, primary, Moreno, Cristina, primary, Merino, Juana, primary, Rodriguez-Otero, Paula, primary, Panizo, Carlos, primary, Prosper, Felipe, primary, San-Miguel, Jesus F., primary, and Paiva, Bruno, primary

Published
2023
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8. Supplementary Figure 2 from The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma

Author

Moreno, Laura, primary, Perez, Cristina, primary, Zabaleta, Aintzane, primary, Manrique, Irene, primary, Alignani, Diego, primary, Ajona, Daniel, primary, Blanco, Laura, primary, Lasa, Marta, primary, Maiso, Patricia, primary, Rodriguez, Idoia, primary, Garate, Sonia, primary, Jelinek, Tomas, primary, Segura, Victor, primary, Moreno, Cristina, primary, Merino, Juana, primary, Rodriguez-Otero, Paula, primary, Panizo, Carlos, primary, Prosper, Felipe, primary, San-Miguel, Jesus F., primary, and Paiva, Bruno, primary

Published
2023
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9. CAR-T Related Cytopenia Profile in Relapsed/Refractory Multiple Myeloma: Results of Patients Treated with ARI0002h, an Academic BCMA-Directed CAR-T Cell

Author

Oliver-Caldes, Aina, primary, Rodríguez-Lobato, Luis Gerardo, additional, Gonzalez-Calle, Veronica, additional, Tovar, Natalia, additional, Cabañas, Valentin, additional, Rodríguez-Otero, Paula, additional, Reguera, Juan Luis, additional, Español-Rego, Marta, additional, Martin-Antonio, Beatriz, additional, Zabaleta, Aintzane, additional, Lasa, Marta, additional, Inogés, Susana, additional, López-Diaz de Cerio, Ascensión, additional, Paiva, Bruno, additional, Varea, Sara, additional, Saez-Peñataro, Joaquin, additional, Juan, Manel, additional, Rosiñol, Laura, additional, Prosper, Felipe, additional, Moraleda, Jose M., additional, Urbano-Ispizua, Álvaro, additional, Pascal, Mariona, additional, Mateos, Maria-Victoria, additional, and Fernandez de Larrea, Carlos, additional

Published
2022
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10. Ultra-Sensitive Assessment of Measurable Residual Disease (MRD) in Peripheral Blood (PB) of Multiple Myeloma (MM) Patients Using Bloodflow

Author

Notarfranchi, Laura, primary, Zherniakova, Anastasiia, additional, Lasa, Marta, additional, Puig, Noemi, additional, Cedena, María Teresa, additional, Martinez-Lopez, Joaquin, additional, Calasanz, María José, additional, Alignani, Diego, additional, Burgos, Leire, additional, Manrique, Irene, additional, Huang, Yi-Ju, additional, Fracowiak, Jochen, additional, Gomez, Clara, additional, De Arriba, Felipe, additional, Rodríguez-Otero, Paula, additional, Palomera, Luis, additional, Sureda, Anna, additional, Clavero Sanchez, Maria Esther, additional, Alvarez, Miguel Angel, additional, Ibanez Garcia, Angela, additional, Hernández, Miguel-Teodoro, additional, Perez, Albert, additional, Gonzalez, Ana Pilar, additional, Ocio, Enrique M., additional, Flores-Montero, Juan, additional, Orfao, Alberto, additional, Lahuerta, Juan Jose, additional, Mateos, María-Victoria, additional, Rosiñol, Laura, additional, Bladé Creixenti, Joan, additional, San-Miguel, Jesús, additional, and Paiva, Bruno, additional

Published
2022
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11. Definition and Clinical Significance of the Monoclonal Gammopathy of Undetermined Significance–Like Phenotype in Patients With Monoclonal Gammopathies.

Author

Burgos, Leire, Tamariz-Amador, Luis-Esteban, Puig, Noemi, Cedena, Maria-Teresa, Guerrero, Camila, Jelínek, Tomas, Johnson, Sarah, Milani, Paolo, Cordon, Lourdes, Perez, Jose J., Lasa, Marta, Termini, Rosalinda, Oriol, Albert, Hernandez, Miguel-Teodoro, Palomera, Luis, Martinez-Martinez, Rafael, de la Rubia, Javier, de Arriba, Felipe, Rios, Rafael, and Gonzalez, Maria-Esther

Published
2023
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13. Biological and Clinical Significance of Undetectable Circulating Tumor Cells (CTCs) in Patients (Pts) with Multiple Myeloma (MM)

Author

Garcés, Juan-José, Termini, Rosalinda, Martín-Sánchez, Esperanza, Lasa, Marta, Perez, Jose J, Gutierrez, Norma C., Fernández, Manuela, Calasanz, Maria Jose, Rosiñol, Laura, Hernández Garcia, Miguel Teodoro, Oriol, Albert, Sureda Balari, Anna Maria, Perez Montaña, Albert, Ocio, Enrique M, Casanova Espinosa, Maria, Prosper, Felipe, Martinez-Lopez, Joaquin, Labrador, Jorge, Gonzalez Garcia, Esther, Ríos, Rafael, Escalante, Fernando, Bargay, Joan, Cabezudo, Elena, Cabañas, Valentín, Weinhold, Niels, Roccaro, Aldo, Avet-Loiseau, Herve, Orfao, Alberto, Blade Creixenti, Joan, Mateos, Maria Victoria, Lahuerta Palacios, Juan Jose, San-Miguel, Jesus, Cedena, María T, Puig, Noemi, and Paiva, Bruno

Published
2023
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14. Minimally Invasive Assessment of Measurable Residual Disease (MRD) in Multiple Myeloma (MM)

Author

Gonzalez, Carmen, Lasa, Marta, Notarfranchi, Laura, Agullo, Cristina, Buenache Cuenda, Natalia, Zherniakova, Anastasiia, Castro, Sergio, Pérez, José Juan, Gonzalez-Calle, Veronica, Cedena Romero, Maria Teresa, Barrio, Santiago, Martín-Muñoz, Alejandro, Burgos, Leire, Alignani, Diego, Calasanz, Maria Jose, Rodriguez Otero, Paula, Rosiñol, Laura, De Arriba, Felipe, Ocio, Enrique M, Rocafiguera, Albert Oriol, Palomera, Luis, González-Montes, Yolanda, Sureda Balari, Anna Maria, Hernandez Garcia, Miguel Teodoro, Clavero Sanchez, Maria Esther, Ibanez Garcia, Angela, Gomez, Clara, Orfao, Alberto, Mateos, Maria Victoria, Lahuerta Palacios, Juan Jose, Bladé, Joan, San-Miguel, Jesus, Martinez-Lopez, Joaquin, Puig, Noemi, and Paiva, Bruno

Published
2023
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