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Your search keyword '"Leonard Appleman"' showing total 11 results
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11 results on '"Leonard Appleman"'

1. LBA02-11 UPDATED PROGRESSION-FREE SURVIVAL FROM PRESTO: A PHASE 3 RANDOMIZED STUDY OF ANDROGEN ANNIHILATION FOR HIGH-RISK BIOCHEMICALLY RELAPSED PROSTATE CANCER (AFT-19)

Author

Rahul Aggarwal, Scott Eggener, Glenn Heller, Habn Xiao, David Hillman, Joel Picus, Jennifer Wang, Mary Ellen Taplin, Tanya Dorff, Leonard Appleman, Doug Weckstein, Akash Patnaik, Alan Bryce, Dan Shevrin, Susan Halabi, James Mohler, Daniel Anderson, Arpit Rao, Scott Tagawa, Alan Tan, Charles Ryan, and Michael Morris

Subjects
Urology
Published
2023
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2. Supplementary Table S2 from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

59 probesets from an analysis of blood These are probesets for which the null hypothesis was rejected and the change over time averaged over treatment groups was {greater than or equal to}1.2-fold.

Published
2023
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3. Supplementary Figure S1 from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

CONSORT diagram.

Published
2023
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4. Supplementary Table S3 from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

Genes from an analysis of tumor biopsies with {greater than or equal to}1.3-fold differences between treatment groups over time. Thirty-seven probesets identified from gene expression analysis.

Published
2023
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5. Supplementary Information from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

Supplementary Information

Published
2023
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6. Supplementary Figure S2 from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

Scatter-plot matrix of change from baseline (CFB) of CD3+, CD4+, and CD8+ cell percentages among the 36 patients. The diagonal panels give kernel density estimates and histograms summarizing the univariate distributions for the individual cell-type percentages.

Published
2023
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7. Supplementary Table S4 from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

Genes from whole blood analysis with {greater than or equal to}1.2-fold differences between treatment groups over time. Twenty-four probesets identified from gene expression analysis.

Published
2023
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8. Supplementary Figure S3 from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

Change from baseline PD-L1 expression. Data included are for patients with matched fresh tumor biopsies at baseline and cycle 2, day 8 (C2D8) of nivolumab treatment. Each solid line represents a patient. The horizontal dotted line represents 5% PD-L1 expression.

Published
2023
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9. Supplementary Table S1 from Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

Author

Mario Sznol, Jason S. Simon, John F. Kurland, Maria Jure-Kunkel, Shivani Srivastava, Petra Ross-Macdonald, Scott D. Chasalow, Tina C. Young, Lewis Cohen, Laurence Albiges, Lawrence Fong, Leonard Appleman, Elizabeth R. Plimack, Michael R. Harrison, Brendan Curti, Douglas G. McNeel, Jose Luis Perez-Gracia, Walter M. Stadler, Harriet Kluger, Charles G. Drake, David F. McDermott, Bernard Escudier, Mayer N. Fishman, and Toni K. Choueiri

Abstract

108 probesets from an analysis of tumor biopsies These are probesets for which the null hypothesis was rejected and the change over time averaged over treatment groups was {greater than or equal to}1.3-fold.

Published
2023
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10. Disease-free Survival Analysis for Patients with High-risk Muscle-invasive Urothelial Carcinoma from the Randomized CheckMate 274 Trial by PD-L1 Combined Positive Score and Tumor Cell Score

Author

Matthew D. Galsky, Dean F. Bajorin, Johannes Alfred Witjes, Jürgen E. Gschwend, Yoshihiko Tomita, Federico Nasroulah, Jun Li, Sandra Collette, Begoña P. Valderrama, Marc-Oliver Grimm, Leonard Appleman, Gwenaelle Gravis, Andrea Necchi, Dingwei Ye, Frank Stenner, Megan Wind-Rotolo, Joshua Zhang, and Keziban Ünsal-Kaçmaz

Subjects
All institutes and research themes of the Radboud University Medical Center, Urology, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15]
Abstract

Contains fulltext : 293187.pdf (Publisher’s version ) (Open Access)

Published
2023

11. Safety and Efficacy of Immune Checkpoint Inhibitors in Patients with Advanced Penile Squamous Cell Carcinoma: An International Study from the Global Society of Rare Genitourinary Tumors

Author

Talal El Zarif, Amin Nassar, Gregory R. Pond, Tony Zibo Zhuang, Viraj A. Master, Bassel Nazha, Scot Niglio, Nicholas Simon, Andrew W. Hahn, Curtis A. Pettaway, Shi-Ming Tu, Noha Abdel-Wahab, Maud Velev, Ronan Flippot, Sebastiano Buti, Marco Maruzzo, Arjun Mittra, Jinesh Gheeya, Yuanquan Yang, Pablo Alvarez Rodriguez, Daniel Castellano, Guillermo de Velasco, Giandomenico Roviello, Lorenzo Antonuzzo, Rana R. McKay, Bruno Vincenzi, Alessio Cortellini, Gavin Hui, Alexandra Drakaki, Michael Glover, Ali Raza Khaki, Edward El-Am, Nabil Adra, Tarek H. Mouhieddine, Vaibhav Patel, Aida Piedra Cascon, Angela Gernone, Nancy B. Davis, Harrison Matthews, Michael R. Harrison, Ravindran Kanesvaran, Giulia Claire Giudice, Pedro Barata, Alberto Farolfi, Jae Lyun Lee, Matthew I. Milowsky, Charlotte Stahlfeld, Leonard Appleman, Joseph Kim, Dory Freeman, Toni K. Choueiri, Philippe E. Spiess, Andrea Necchi, Andrea Apolo, and Guru P. Sonpavde

Published
2023
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