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144 results on '"Malik, Vasanti"'

13. Consumption of 100% Fruit Juice and Body Weight in Children and Adults

Author

Nguyen, Michelle, primary, Jarvis, Sarah E., additional, Chiavaroli, Laura, additional, Mejia, Sonia Blanco, additional, Zurbau, Andreea, additional, Khan, Tauseef A., additional, Tobias, Deirdre K., additional, Willett, Walter C., additional, Hu, Frank B., additional, Hanley, Anthony J., additional, Birken, Catherine S., additional, Sievenpiper, John L., additional, and Malik, Vasanti S., additional

Published
2024
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15. Effects of a dietary intervention on cardiometabolic risk and food consumption in a workplace.

Author

Shrestha, Archana, Tamrakar, Dipesh, Ghinanju, Bhawana, Shrestha, Deepa, Khadka, Parashar, Adhikari, Bikram, Shrestha, Jayana, Waiwa, Suruchi, Pyakurel, Prajjwal, Bhandari, Niroj, Karmacharya, Biraj Man, Shrestha, Akina, Shrestha, Rajeev, Bhatta, Rajendra Dev, Malik, Vasanti, Mattei, Josiemer, and Spiegelman, Donna

Subjects
FOOD consumption, WHOLE grain foods, DIASTOLIC blood pressure, SYSTOLIC blood pressure, LDL cholesterol, GLYCOSYLATED hemoglobin, BLOOD pressure
Abstract

Background: Worksite-based health programs have shown positive impacts on employee health and have led to significant improvements in cardiovascular risk factor profiles. We aimed to determine the effect of cafeteria intervention on cardio-metabolic risk factors diet in a worksite setting (Dhulikhel Hospital) in Nepal. Methods: In this one-arm pre-post intervention study, we recruited 277 non-pregnant hospital employees aged 18–60 with prediabetes or pre-hypertension. The study was registered in clinicaltrials.gov (NCT03447340; 2018/02/27). All four cafeterias in the hospital premises received cafeteria intervention encouraging healthy foods and discouraging unhealthy foods for six months. We measured blood pressure, fasting glucose level, glycated hemoglobin, cholesterol in the laboratory, and diet intake (in servings per week) using 24-hour recall before and six months after the intervention. The before and after measures were compared using paired-t tests. Results: After six months of cafeteria intervention, the median consumption of whole grains, mono/polyunsaturated fat, fruits, vegetable and nuts servings per week increased by 2.24(p<0.001), 2.88(p<0.001), 0.84(p<0.001) 2.25(p<0.001) and nuts 0.55 (p<0.001) servings per week respectively. The median consumption of refined grains decreased by 5.07 servings per week (p<0.001). Mean systolic and diastolic blood pressure decreased by 2 mmHg (SE = 0.6; p = 0.003) and 0.1 mmHg (SE = 0.6; p = 0.008), respectively. The low-density lipoprotein (LDL) was significantly reduced by 6 mg/dL (SE = 1.4; p<0.001). Conclusion: Overall, we found a decrease in consumption of refined grains and an increase in consumption of whole grains, unsaturated fats, fruits, and nuts observed a modest reduction in blood pressure and LDL cholesterol following a 6-month cafeteria-based worksite intervention incorporating access to healthy foods. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Underweight in the first 2 years of life and nutrition risk in later childhood: a prospective cohort study.

Author

South, Courtney A., Keown‐Stoneman, Charles D. G., Birken, Catherine S., Malik, Vasanti, Zlotkin, Stanley H., and Maguire, Jonathon L.

Subjects
RISK assessment, LEANNESS, MALNUTRITION, FOOD consumption, RESEARCH funding, BODY mass index, BODY weight, LONGITUDINAL method, STATURE, ODDS ratio, FOOD habits, CONFIDENCE intervals, DISEASE risk factors, CHILDREN
Abstract

Background: Children with underweight in the first 2 years have lower body mass index z‐score (zBMI) and height‐for‐age z‐score (HAZ) in later childhood. It is not known if underweight in the first 2 years is associated with nutrition risk in later childhood. Objective: (1) Determine the relationship between underweight (zBMI < −2) in the first 2 years and nutrition risk measured by the Nutrition Screening for Toddlers and Preschoolers (NutriSTEP) score from 18 months to 5 years. (2) Explore the relationship between underweight in the first 2 years and the NutriSTEP subscores for eating behaviours and dietary intake from 18 months to 5 years. Methods: This was a prospective study, including healthy full‐term children in Canada aged 0–5 years. zBMI was calculated using measured heights and weights and the WHO growth standards. NutriSTEP score was measured using a parent‐completed survey and ranged from 0 to 68. Nutrition risk was defined as a score ≥21. Linear mixed effects models were used. Results: Four thousand nine hundred twenty‐nine children were included in this study. At enrolment, 51.9% of participants were male. The prevalence of underweight children was 8.8%. Underweight in the first 2 years was associated with higher NutriSTEP (0.79, 95% CI: 0.29,1.29), higher eating behaviour subscore (0.24, 95% CI: 0.03, 0.46) at 3 years and higher odds of nutrition risk (OR: 1.39, 95% CI: 1.07,1.82) at 5 years. Conclusions: Children with underweight in the first 2 years had higher nutrition risk in later childhood. Further research is needed to understand the factors which influence these relationships. Key points: In this prospective cohort study of 4929 children aged 0–5 years, children with underweight in the first 2 years of life had higher odds of nutrition risk at 5 years of age compared to children without underweight in the first 2 years (p = 0.02). Further research is needed to understand the factors which influence these relationships. [ABSTRACT FROM AUTHOR]

Published
2024
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21. P22-010-23 Coronary Heart Effectiveness Assessment of the Portfolio Diet in Primary Care (CHEAP) Trial: Protocol for a Randomized Controlled Trial

Author

Chiavaroli, Laura, primary, Kavanagh, Meaghan, additional, Glenn, Andrea, additional, Chen, Victoria, additional, Back, Songhee, additional, Khan, Tauseef, additional, Chow, Chi-Ming, additional, Vallis, Michael, additional, Grant, Shannan, additional, Joy, Phillip, additional, Sherifali, Diana, additional, Agarwal, Payal, additional, Snelgrove-Clarke, Erna, additional, Juni, Peter, additional, DaCosta, Bruno, additional, Greiver, Michelle, additional, Pinto, Andrew, additional, Booth, Gillian, additional, Udell, Jacob, additional, Farkouh, Michael, additional, Chan, Brian, additional, Isaranuwatchai, Wanrudee, additional, Beyene, Joseph, additional, De Souza, Russel, additional, Malik, Vasanti, additional, El-Sohemy, Ahmed, additional, L'Abbe, Mary, additional, Lee, Jennifer, additional, Boucher, Beatrice, additional, Comelli, Elena, additional, Salas-Salvadó, Jordi, additional, Watson, William, additional, Josse, Robert, additional, Lofters, Aisha, additional, Rackal, Julia, additional, Holmes, Candice, additional, Srichaikul, Korbua, additional, Noble, Matt, additional, Symington, Amy, additional, St-Onge, Marie-Pierre, additional, Leiter, Lawrence, additional, Kendall, Cyril, additional, Jenkins, David, additional, and Sievenpiper, John, additional

Published
2023
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23. Portfolio Diet Score and Risk of Cardiovascular Disease:Findings From 3 Prospective Cohort Studies

Author

Glenn, Andrea J., Guasch-Ferré, Marta, Malik, Vasanti S., Kendall, Cyril W.C., Manson, Jo Ann E., Rimm, Eric B., Willett, Walter C., Sun, Qi, Jenkins, David J.A., Hu, Frank B., Sievenpiper, John L., Glenn, Andrea J., Guasch-Ferré, Marta, Malik, Vasanti S., Kendall, Cyril W.C., Manson, Jo Ann E., Rimm, Eric B., Willett, Walter C., Sun, Qi, Jenkins, David J.A., Hu, Frank B., and Sievenpiper, John L.

Abstract

BACKGROUND: The plant-based Portfolio dietary pattern includes recognized cholesterol-lowering foods (ie, plant protein, nuts, viscous fiber, phytosterols, and plant monounsaturated fats) shown to improve several cardiovascular disease (CVD) risk factors in randomized controlled trials. However, there is limited evidence on the role of long-term adherence to the diet and CVD risk. The primary objective was to examine the relationship between the Portfolio Diet Score (PDS) and the risk of total CVD, coronary heart disease (CHD), and stroke. METHODS: We prospectively followed 73 924 women in the Nurses' Health Study (1984-2016), 92 346 women in the Nurses' Health Study II (1991-2017), and 43 970 men in the Health Professionals Follow-up Study (1986-2016) without CVD or cancer at baseline. Diet was assessed using validated food frequency questionnaires at baseline and every 4 years using a PDS that positively ranks plant protein (legumes), nuts and seeds, viscous fiber sources, phytosterols (mg/day), and plant monounsaturated fat sources, and negatively ranks foods high in saturated fat and cholesterol. RESULTS: During up to 30 years of follow-up, 16 917 incident CVD cases, including 10 666 CHD cases and 6473 strokes, were documented. After multivariable adjustment for lifestyle factors and a modified Alternate Healthy Eating Index (excluding overlapping components), comparing the highest with the lowest quintile, participants with a higher PDS had a lower risk of total CVD (pooled hazard ratio [HR], 0.86 [95% CI, 0.81-0.92]; Ptrend<0.001), CHD (pooled HR, 0.86 [95% CI, 0.80-0.93]; Ptrend=0.0001), and stroke (pooled HR, 0.86 [95% CI, 0.78-0.95]; Ptrend=0.0003). In addition, a 25-percentile higher PDS was associated with a lower risk of total CVD (pooled HR, 0.92 [95% CI, 0.89-0.95]), CHD (pooled HR, 0.92 [95% CI, 0.88-0.95]), and stroke (pooled HR, 0.92 [95% CI, 0.87-0.96]). Results remained consistent across sensitivity and most

Published
2023

25. Rationale, Design and Participants Baseline Characteristics of a Crossover Randomized Controlled Trial of the Effect of Replacing SSBs with NSBs versus Water on Glucose Tolerance, Gut Microbiome and Cardiometabolic Risk in Overweight or Obese Adult SSB Consumer: Strategies to Oppose SUGARS with Non-Nutritive Sweeteners or Water (STOP Sugars NOW) Trial and Ectopic Fat Sub-Study

Author

Ayoub-Charette, Sabrina, primary, McGlynn, Néma D., additional, Lee, Danielle, additional, Khan, Tauseef Ahmad, additional, Blanco Mejia, Sonia, additional, Chiavaroli, Laura, additional, Kavanagh, Meaghan E., additional, Seider, Maxine, additional, Taibi, Amel, additional, Chen, Chuck T., additional, Ahmed, Amna, additional, Asbury, Rachel, additional, Erlich, Madeline, additional, Chen, Yue-Tong, additional, Malik, Vasanti S., additional, Bazinet, Richard P., additional, Ramdath, D. Dan, additional, Logue, Caomhan, additional, Hanley, Anthony J., additional, Kendall, Cyril W. C., additional, Leiter, Lawrence A., additional, Comelli, Elena M., additional, and Sievenpiper, John L., additional

Published
2023
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26. Abstract MP62: Fatty Acid Biomarkers of 15:0, 17:0 and Trans 16:1n-7 and Incident Coronary Heart Disease and Stroke: A Pooling Project of 15 Prospective Cohorts in the Fatty Acids and Outcomes Research Consortium

Author

Ardisson Korat, Andres V, primary, Qian, Frank, additional, Malik, Vasanti, additional, Lehr, Marcus, additional, Imamura, Fumiaki, additional, Tintle, Nathan, additional, Laakso, Markku, additional, van Dam, Rob, additional, Harris, William, additional, Marklund, Matti, additional, Samieri, Cecilia, additional, Senn, MacKenzie, additional, Leander, Karin, additional, Forouhi, Nita, additional, Riserus, Ulf, additional, Chien, Kou-Liong, additional, Chen, Amelia, additional, Wood, Alexis, additional, Guan, Weihua, additional, Tsai, Michael Y, additional, Murphy, Rachel, additional, Siscovick, David S, additional, Lemaitre, Rozenn, additional, Mozaffarian, Dariush, additional, and Sun, Qi, additional

Published
2023
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29. Sugar-sweetened beverage consumption and weight gain in children and adults: a systematic review and meta-analysis of prospective cohort studies and randomized controlled trials

Author

Nguyen, Michelle, primary, Jarvis, Sarah E., additional, Tinajero, Maria G., additional, Yu, Jiayue, additional, Chiavaroli, Laura, additional, Mejia, Sonia Blanco, additional, Khan, Tauseef A., additional, Tobias, Deirdre K., additional, Willett, Walter C., additional, Hu, Frank B., additional, Hanley, Anthony J., additional, Birken, Catherine S., additional, Sievenpiper, John L., additional, and Malik, Vasanti S., additional

Published
2022
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30. Important Food Sources of Sugars and Type 2 Diabetes: A Systematic Review and Meta-analysis of Prospective Cohort Studies

Author

Khan, Tauseef, primary, Chen, Victoria, additional, Lee, Danielle, additional, Tayyiba, Mobushra, additional, Saleh, Ahmed, additional, Ahmed, Amna, additional, Au-Yeung, Fei, additional, Mejia, Sonia Blanco, additional, Chiavaroli, Laura, additional, Malik, Vasanti, additional, Leiter, Lawrence, additional, Wolever, Thomas, additional, Kendall, Cyril, additional, and Sievenpiper, John, additional

Published
2022
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35. White rice, brown rice and the risk of type 2 diabetes: a systematic review and meta-analysis

Author

Yu, Jiayue, primary, Balaji, Bhavadharini, additional, Tinajero, Maria, additional, Jarvis, Sarah, additional, Khan, Tauseef, additional, Vasudevan, Sudha, additional, Ranawana, Viren, additional, Poobalan, Amudha, additional, Bhupathiraju, Shilpa, additional, Sun, Qi, additional, Willett, Walter, additional, Hu, Frank B, additional, Jenkins, David J A, additional, Mohan, Viswanathan, additional, and Malik, Vasanti S, additional

Published
2022
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36. Relation of change or substitution of low-and no-calorie sweetened beverages with cardiometabolic outcomes: A systematic review and meta-analysis of prospective cohort studies

Author

Lee, Jennifer J., primary, Khan, Tauseef A., primary, McGlynn, Nema, primary, Malik, Vasanti S., primary, Hill, James O., primary, Leiter, Lawrence A., primary, Jeppesen, Per Bendix, primary, Rahelić, Dario, primary, Kahleová, Hana, primary, Salas-Salvadó, Jordi, primary, Kendall, Cyril W. C., primary, and Sievenpiper, John L., primary

Published
2022
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38. Important Food Sources of Fructose-Containing Sugars and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Controlled Trials

Author

Lee, Danielle, primary, Chiavaroli, Laura, additional, Ayoub-Charette, Sabrina, additional, Khan, Tauseef A., additional, Zurbau, Andreea, additional, Au-Yeung, Fei, additional, Cheung, Annette, additional, Liu, Qi, additional, Qi, Xinye, additional, Ahmed, Amna, additional, Choo, Vivian L., additional, Blanco Mejia, Sonia, additional, Malik, Vasanti S., additional, El-Sohemy, Ahmed, additional, de Souza, Russell J., additional, Wolever, Thomas M. S., additional, Leiter, Lawrence A., additional, Kendall, Cyril W. C., additional, Jenkins, David J. A., additional, and Sievenpiper, John L., additional

Published
2022
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40. Sugar-Sweetened Beverage and 100% Fruit Juice Consumption on Body Weight in Children and Adults: A Systematic Review and Meta-Analysis

Author

Nguyen, Michelle, primary, Jarvis, Sarah, additional, Tinajero, Maria, additional, Yu, Jiayue, additional, Chiavaroli, Laura, additional, Mejia, Sonia Blanco, additional, Khan, Tauseef, additional, Willett, Walter, additional, Hu, Frank, additional, Birken, Catherine, additional, Sievenpiper, John, additional, and Malik, Vasanti, additional

Published
2022
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41. A Web-Based Health Application to Translate Nutrition Therapy for Cardiovascular Risk Reduction in Primary Care (PortfolioDiet.app): Quality Improvement and Usability Testing Study

Author

Kavanagh, Meaghan E, primary, Chiavaroli, Laura, additional, Glenn, Andrea J, additional, Heijmans, Genevieve, additional, Grant, Shannan M, additional, Chow, Chi-Ming, additional, Josse, Robert G, additional, Malik, Vasanti S, additional, Watson, William, additional, Lofters, Aisha, additional, Holmes, Candice, additional, Rackal, Julia, additional, Srichaikul, Kristie, additional, Sherifali, Diana, additional, Snelgrove-Clarke, Erna, additional, Udell, Jacob A, additional, Juni, Peter, additional, Booth, Gillian L, additional, Farkouh, Michael E, additional, Leiter, Lawrence A, additional, Kendall, Cyril WC, additional, Jenkins, David JA, additional, and Sievenpiper, John L, additional

Published
2022
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43. Association of Low- and No-Calorie Sweetened Beverages as a Replacement for Sugar-Sweetened Beverages With Body Weight and Cardiometabolic Risk

Author

McGlynn, Néma D., primary, Khan, Tauseef Ahmad, additional, Wang, Lily, additional, Zhang, Roselyn, additional, Chiavaroli, Laura, additional, Au-Yeung, Fei, additional, Lee, Jennifer J., additional, Noronha, Jarvis C., additional, Comelli, Elena M., additional, Blanco Mejia, Sonia, additional, Ahmed, Amna, additional, Malik, Vasanti S., additional, Hill, James O., additional, Leiter, Lawrence A., additional, Agarwal, Arnav, additional, Jeppesen, Per B., additional, Rahelić, Dario, additional, Kahleová, Hana, additional, Salas-Salvadó, Jordi, additional, Kendall, Cyril W. C., additional, and Sievenpiper, John L., additional

Published
2022
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45. Abstract 016: Artificially Sweetened Beverage Consumption, Plasma Metabolomics, And Risk Of Type 2 Diabetes Among US Adults

Author

Haslam, Danielle E, primary, Wang, Biqi, additional, Li, Jun, additional, Guasch, Marta, additional, Liang, Liming, additional, Clish, Clary B, additional, Manson, Joann E, additional, Tobias, Deirdre K, additional, Wittenbecher, Clemens, additional, Willett, Walter C, additional, Stampfer, Meir J, additional, Herman, Mark A, additional, Dupuis, Josee, additional, McKeown, Nicola M, additional, Malik, Vasanti S, additional, Meigs, James B, additional, Hu, Frank B, additional, and Bhupathiraju, Shilpa N, additional

Published
2022
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46. A Web-Based Health Application to Translate Nutrition Therapy for Cardiovascular Risk Reduction in Primary Care (PortfolioDiet.app): Quality Improvement and Usability Testing Study (Preprint)

Author

Kavanagh, Meaghan E, primary, Chiavaroli, Laura, additional, Glenn, Andrea J, additional, Heijmans, Genevieve, additional, Grant, Shannan M, additional, Chow, Chi-Ming, additional, Josse, Robert G, additional, Malik, Vasanti S, additional, Watson, William, additional, Lofters, Aisha, additional, Holmes, Candice, additional, Rackal, Julia, additional, Srichaikul, Kristie, additional, Sherifali, Diana, additional, Snelgrove-Clarke, Erna, additional, Udell, Jacob A, additional, Juni, Peter, additional, Booth, Gillian L, additional, Farkouh, Michael E, additional, Leiter, Lawrence A, additional, Kendall, Cyril WC, additional, Jenkins, David JA, additional, and Sievenpiper, John L, additional

Published
2021
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47. Prevalence and risk factors of MRI-defined brain infarcts among Chinese adults.

Author

Jing Wu, Yongxiang Gao, Malik, Vasanti, Xiang Gao, Ruiqi Shan, Jun Lv, Yi Ning, Bo Wang, and Liming Li

Subjects
LACUNAR stroke, YOUNG adults, MAGNETIC resonance imaging, LOGISTIC regression analysis, PERIODIC health examinations, ADULTS
Abstract

Background: Few studies have explored the prevalence and risk factors of brain infarcts (BI) detected bymagnetic resonance imaging (MRI) in China. The purpose was to evaluate the prevalence and risk factors of brain infarcts (BI) detected by magnetic resonance imaging (MRI) in 1.4 million Chinese adults. Methods: This was a multicenter cross-sectional study conducted on 1,431,527 participants aged ≥18 years (mean age: 46.4 years) who underwent MRI scans in health examinations from 28 provinces of China in 2018. MRI-defined BI was defined as focal parenchymal lesions ≥3mm. Multivariable logistic regression analyses were performed to evaluate risk factors associated with MRI-defined BI. Results: The age- and sex-standardized prevalence of MRI-defined BI, lacunar and non-lacunar infarcts were 5.79% (5.75-5.83%), 4.56% (4.52-4.60%), and 1.23% (1.21-1.25%), respectively. The sex-standardized prevalence of MRI-defined BI ranged from 0.46% among those aged 18-29 years to 37.33% among those aged ≥80 years. Men (6.30%) had a higher age-standardized prevalence of MRI-defined BI than women (5.28%). The highest age- and sex-standardized prevalence of MRI-defined BI was observed in the Northwest (8.34%) and Northeast (8.02%) regions, while the lowest prevalence was observed in the Southwest (4.02%). A higher risk of MRI-defined BI was associated with being male [odd ratio (OR) 1.17, 95% CI 1.15-1.19], older age (OR per 10-year increments 2.33, 2.31-2.35), overweight (1.12, 1.10-1.14) or obesity (1.18, 1.16-1.21), hypertension (1.80, 1.77-1.83), diabetes (1.24, 1.21-1.26), and dyslipidemia (1.07, 1.05-1.08). Conclusion: MRI-defined BI is highly prevalent in China, even among young adults. MRI-defined BI was associated with being male, older age, living in the northern region, and metabolic conditions. [ABSTRACT FROM AUTHOR]

Published
2022
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48. Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies.

Author

Lee, Jennifer J., Khan, Tauseef A., McGlynn, Nema, Malik, Vasanti S., Hill, James O., Leiter, Lawrence A., Jeppesen, Per Bendix, Rahelić, Dario, Kahleová, Hana, Salas-Salvadó, Jordi, Kendall, Cyril W.C., and Sievenpiper, John L.

Subjects
OBESITY, RESEARCH, META-analysis, RESEARCH methodology, CARDIOVASCULAR diseases, WATER, EVALUATION research, TYPE 2 diabetes, COMPARATIVE studies, RESEARCH funding, LONGITUDINAL method
Abstract

Background: Adverse associations of low- and no-calorie sweetened beverages (LNCSB) with cardiometabolic outcomes in observational studies may be explained by reverse causality and residual confounding.Purpose: To address these limitations we used change analyses of repeated measures of intake and substitution analyses to synthesize the association of LNCSB with cardiometabolic outcomes.Data Sources: MEDLINE, Embase, and the Cochrane Library were searched up to 10 June 2021 for prospective cohort studies with ≥1 year of follow-up duration in adults.Study Selection: Outcomes included changes in clinical measures of adiposity, risk of overweight/obesity, metabolic syndrome, type 2 diabetes (T2D), cardiovascular disease, and total mortality.Data Extraction: Two independent reviewers extracted data, assessed study quality, and assessed certainty of evidence using GRADE. Data were pooled with a random-effects model and expressed as mean difference (MD) or risk ratio (RR) and 95% CI.Data Synthesis: A total of 14 cohorts (416,830 participants) met the eligibility criteria. Increase in LNCSB intake was associated with lower weight (5 cohorts, 130,020 participants; MD -0.008 kg/year [95% CI -0.014, -0.002]). Substitution of LNCSB for sugar-sweetened beverages (SSB) was associated with lower weight (three cohorts, 165,579 participants; MD, -0.12 [-0.14, -0.10,] kg/y) and lower incidence of obesity (OB) (one cohort, 15,765 participants; RR 0.88 [95% CI 0.88, 0.89]), coronary heart disease (six cohorts, 233,676 participants; 0.89 [0.81, 0.98]), cardiovascular disease mortality (one cohort, 118,363 participants; 0.95 [0.90, 0.99]), and total mortality (one cohort, 118,363 participants; 0.96 [0.94, 0.98]) with no adverse associations across other outcomes. Substitution of water for SSB showed lower weight (three cohorts, 165,579 participants; MD -0.10 kg/year [-0.13, -0.06]), lower waist circumference (one cohort, 173 participants; -2.71 cm/year [-4.27, -1.15]) and percent body fat (one cohort, 173 participants; -1.51% per year [-2.61, -0.42]), and lower incidence of OB (one cohort, 15,765 participants; RR 0.85 [0.75, 0.97]) and T2D (three cohorts, 281,855 participants; 0.96 [0.94, 0.98]). Substitution of LNCSB for water showed no adverse associations.Limitations: The evidence was low to very low certainty owing to downgrades for imprecision, indirectness, and/or inconsistency.Conclusions: LNCSB were not associated with cardiometabolic harm in analyses that model the exposure as change or substitutions. The available evidence provides some indication that LNCSB in their intended substitution for SSB may be associated with cardiometabolic benefit, comparable with the standard of care, water. [ABSTRACT FROM AUTHOR]

Published
2022
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50. Intergenerational Transmission of Obesity from Mothers to Their Offspring: Trends and Associated Factors Derived from the Malaysian National Health and Morbidity Survey (NHMS).

Author

Mohamed, Nur Nadia, Rohana, Abdul Jalil, Hamid, Noor Aman A, Hu, Frank B., Malik, Vasanti S., Mohd Yusoff, Muhammad Fadhli, and Aris, Tahir

Abstract

Along with the increasing overweight and obesity trends among adults and children globally, numerous studies have suggested a strong association between maternal overweight and obesity among their offspring. We sought to report the prevalence and associated factors of intergenerational overweight and obesity among mother–child pairs in Malaysia from 2006 to 2015. Data were analysed from three waves of the Malaysian National Health and Morbidity Survey, a population-based cross-sectional study conducted in 2006, 2011 and 2015. A mother and the youngest child from each household formed 'mother–child pairs' and were grouped according to their body mass index categories. A multivariable logistic regression model was performed to determine the factors associated with overweight mother/overweight child pairs (OWM/OWC), with normal weight mother/normal weight child pairs (NWM/NWC) as the reference group. The prevalence of OWM/OWC increased from 15.3% to 21.7%, while the prevalence of NWM/NWC decreased from 28.4% to 23.8% between 2006 and 2015. Older maternal age and having primary and secondary education levels were positively associated with OWM/OWC. Conversely, older child age, Chinese ethnicity, large household size and low-income households were inversely associated with OWM/OWC. In conclusion, intergenerational weight gain is a worrisome trend in Malaysia. These findings may help in guiding priority setting for obesity prevention strategies in Malaysia. [ABSTRACT FROM AUTHOR]

Published
2022
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