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12 results on '"Martin Walshaw"'

1. Feasibility of dynamic chest radiography to calculate lung volumes in adult people with cystic fibrosis: a pilot study

Author

Matthew Shaw, Thomas Simon FitzMaurice, Paul Stephen McNamara, Dilip Nazareth, Caroline McCann, Martin Walshaw, and Scott Hawkes

Subjects
Medicine, Diseases of the respiratory system, RC705-779
Abstract

Introduction Dynamic chest radiography (DCR) is a novel, low-dose, real-time digital imaging system where software identifies moving thoracic structures and can automatically calculate lung areas. In an observational, prospective, non-controlled, single-centre pilot study, we compared it with whole-body plethysmography (WBP) in the measurement of lung volume subdivisions in people with cystic fibrosis (pwCF).Methods Lung volume subdivisions were estimated by DCR using projected lung area (PLA) during deep inspiration, tidal breathing and full expiration, and compared with same-day WBP in 20 adult pwCF attending routine review. Linear regression models to predict lung volumes from PLA were developed.Results Total lung area (PLA at maximum inspiration) correlated with total lung capacity (TLC) (r=0.78, p

Published
2023
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5. Supplementary Table 4 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer

Author

Triantafillos Liloglou, John K. Field, John Sheard, Martin Walshaw, Chris Warburton, Julie Bryan, John R. Gosney, Soultana Markopoulou, Olaide Y. Raji, and Georgios Nikolaidis

Abstract

PDF file - 53K, Nucleotide sequences of methylation specific primers and probes for the qMSP assays utilised in the BW screening. The ACTB assay is methylation independent

Published
2023
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9. Supplementary Table 3 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer

Author

Triantafillos Liloglou, John K. Field, John Sheard, Martin Walshaw, Chris Warburton, Julie Bryan, John R. Gosney, Soultana Markopoulou, Olaide Y. Raji, and Georgios Nikolaidis

Abstract

PDF file - 57K, Nucleotide sequences of PCR and sequencing primers for Pyrosequencing Methylation Analysis of the promoter targets which qualified for the subsequent BW screening

Published
2023
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10. Supplementary Table 6 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer

Author

Triantafillos Liloglou, John K. Field, John Sheard, Martin Walshaw, Chris Warburton, Julie Bryan, John R. Gosney, Soultana Markopoulou, Olaide Y. Raji, and Georgios Nikolaidis

Abstract

PDF file - 37K, Comparison of internal classification and prediction accuracies and cross-validation consistency of Best multi-marker MDR models identified using the training dataset

Published
2023
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12. Physical activity assessment and vascular function in adults with cystic fibrosis and their non-CF peers

Author

James Shelley, Lynne Boddy, Zoe Knowles, Claire Stewart, Freddy Frost, Dilip Nazareth, Martin Walshaw, and Ellen Dawson

Subjects
Adult, Cystic Fibrosis, Acceleration, Quality of Life, Humans, Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine, Exercise
Abstract

An understanding of physical activity (PA) and related health benefits remains limited in adults with Cystic Fibrosis (CF). Raw acceleration data metrics may improve the quality of assessment and further this understanding. The study aimed to compare PA between people with CF (pwCF) and non-CF peers and examine associations between PA, vascular function and health outcome measures. PA was assessed in 62 participants (31 pwCF) using ActiGraph accelerometers. Vascular function (a marker of cardiovascular disease risk) was assessed using flow-mediated dilatation (FMD) in sub-groups of pwCF (n = 12) and matched controls. Average Euclidean norm minus one (ENMO) (total PA) was significantly lower (

Published
2022

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