1. Sansoninto-induced Lung Injury
- Author
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Kosaku Komiya, Marcelo Takahiro Mitsui, Toru Watanabe, Masaru Nasu, Kazufumi Hiramatsu, and Jun-ichi Kadota
- Subjects
Male ,Internal Medicine ,Humans ,General Medicine ,Lung Injury ,Lung ,Drugs, Chinese Herbal - Abstract
A man in his 70s visited our department for dyspnea with pulmonary infiltrate that was unresolved by antibiotics. He had been taking Sansoninto for five years and doubled its dose a month ago. After discontinuing Sansoninto without any additional medications, his symptoms gradually disappeared, and pulmonary infiltration improved. Drug lymphocyte stimulation tests showed a positive result for Sansoninto. We diagnosed this patient with Sansoninto-induced lung injury. Sansoninto is a combination drug that consists of sansonin, bukuryo, senkyo, chimo, and kanzo. This paper reports the first case of Sansoninto-induced lung injury and discusses the mechanism considering its components. more...
- Published
- 2022