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Your search keyword '"Milan, Gabriella"' showing total 22 results
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22 results on '"Milan, Gabriella"'

2. The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites

Author

Bean, Camilla, Audano, Matteo, Varanita, Tatiana, Favaretto, Francesca, Medaglia, Marta, Gerdol, Marco, Pernas, Lena, Stasi, Fabio, Giacomello, Marta, Herkenne, Stèphanie, Muniandy, Maheswany, Heinonen, Sini, Cazaly, Emma, Ollikainen, Miina, Milan, Gabriella, Pallavicini, Alberto, Pietiläinen, Kirsi H., Vettor, Roberto, Mitro, Nico, and Scorrano, Luca

Published
2021
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4. Author Correction: The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites

Author

Bean, Camilla, Audano, Matteo, Varanita, Tatiana, Favaretto, Francesca, Medaglia, Marta, Gerdol, Marco, Pernas, Lena, Stasi, Fabio, Giacomello, Marta, Herkenne, Stèphanie, Muniandy, Maheswary, Heinonen, Sini, Cazaly, Emma, Ollikainen, Miina, Milan, Gabriella, Pallavicini, Alberto, Pietiläinen, Kirsi H., Vettor, Roberto, Mitro, Nico, and Scorrano, Luca

Published
2022
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8. Supplementary Figure 1 from Therapeutic Effectiveness of Recombinant Cancer Vaccines Is Associated with a Prevalent T-Cell Receptor α Usage by Melanoma-specific CD8+ T Lymphocytes

Author

De Palma, Raffaele, primary, Marigo, Ilaria, primary, Del Galdo, Francesco, primary, De Santo, Carmela, primary, Serafini, Paolo, primary, Cingarlini, Sara, primary, Tüting, Thomas, primary, Lenz, Julia, primary, Basso, Giuseppe, primary, Milan, Gabriella, primary, Zanovello, Paola, primary, and Bronte, Vincenzo, primary

Published
2023
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9. Supplementary Figure 6 from Therapeutic Effectiveness of Recombinant Cancer Vaccines Is Associated with a Prevalent T-Cell Receptor α Usage by Melanoma-specific CD8+ T Lymphocytes

Author

De Palma, Raffaele, primary, Marigo, Ilaria, primary, Del Galdo, Francesco, primary, De Santo, Carmela, primary, Serafini, Paolo, primary, Cingarlini, Sara, primary, Tüting, Thomas, primary, Lenz, Julia, primary, Basso, Giuseppe, primary, Milan, Gabriella, primary, Zanovello, Paola, primary, and Bronte, Vincenzo, primary

Published
2023
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10. Supplementary Figure 4 from Therapeutic Effectiveness of Recombinant Cancer Vaccines Is Associated with a Prevalent T-Cell Receptor α Usage by Melanoma-specific CD8+ T Lymphocytes

Author

De Palma, Raffaele, primary, Marigo, Ilaria, primary, Del Galdo, Francesco, primary, De Santo, Carmela, primary, Serafini, Paolo, primary, Cingarlini, Sara, primary, Tüting, Thomas, primary, Lenz, Julia, primary, Basso, Giuseppe, primary, Milan, Gabriella, primary, Zanovello, Paola, primary, and Bronte, Vincenzo, primary

Published
2023
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11. Supplementary Figure 2 from Therapeutic Effectiveness of Recombinant Cancer Vaccines Is Associated with a Prevalent T-Cell Receptor α Usage by Melanoma-specific CD8+ T Lymphocytes

Author

De Palma, Raffaele, primary, Marigo, Ilaria, primary, Del Galdo, Francesco, primary, De Santo, Carmela, primary, Serafini, Paolo, primary, Cingarlini, Sara, primary, Tüting, Thomas, primary, Lenz, Julia, primary, Basso, Giuseppe, primary, Milan, Gabriella, primary, Zanovello, Paola, primary, and Bronte, Vincenzo, primary

Published
2023
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12. Data from Therapeutic Effectiveness of Recombinant Cancer Vaccines Is Associated with a Prevalent T-Cell Receptor α Usage by Melanoma-specific CD8+ T Lymphocytes

Author

De Palma, Raffaele, primary, Marigo, Ilaria, primary, Del Galdo, Francesco, primary, De Santo, Carmela, primary, Serafini, Paolo, primary, Cingarlini, Sara, primary, Tüting, Thomas, primary, Lenz, Julia, primary, Basso, Giuseppe, primary, Milan, Gabriella, primary, Zanovello, Paola, primary, and Bronte, Vincenzo, primary

Published
2023
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13. Supplementary Figure 5 from Therapeutic Effectiveness of Recombinant Cancer Vaccines Is Associated with a Prevalent T-Cell Receptor α Usage by Melanoma-specific CD8+ T Lymphocytes

Author

De Palma, Raffaele, primary, Marigo, Ilaria, primary, Del Galdo, Francesco, primary, De Santo, Carmela, primary, Serafini, Paolo, primary, Cingarlini, Sara, primary, Tüting, Thomas, primary, Lenz, Julia, primary, Basso, Giuseppe, primary, Milan, Gabriella, primary, Zanovello, Paola, primary, and Bronte, Vincenzo, primary

Published
2023
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14. Supplementary Figure 3 from Therapeutic Effectiveness of Recombinant Cancer Vaccines Is Associated with a Prevalent T-Cell Receptor α Usage by Melanoma-specific CD8+ T Lymphocytes

Author

De Palma, Raffaele, primary, Marigo, Ilaria, primary, Del Galdo, Francesco, primary, De Santo, Carmela, primary, Serafini, Paolo, primary, Cingarlini, Sara, primary, Tüting, Thomas, primary, Lenz, Julia, primary, Basso, Giuseppe, primary, Milan, Gabriella, primary, Zanovello, Paola, primary, and Bronte, Vincenzo, primary

Published
2023
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15. Edmonton Obesity Staging System: an improvement by cardiopulmonary exercise testing

Author

Bettini, Silvia, Quinto, Giulia, Neunhaeuserer, Daniel, Battista, Francesca, Belligoli, Anna, Milan, Gabriella, Gasperetti, Andrea, Vettor, Roberto, Ermolao, Andrea, and Busetto, Luca

Abstract

Background/Objectives: Different approaches are used to classify obesity severity. Beyond classical anthropometric measurements, the Edmonton Obesity Staging System (EOSS) considers medical, physical and psychological parameters. However, this method has some limitations, principally due to the absence of an objective measure for physical impairment. The aim of our study is thus to overcome this limitation suggesting a new functional parameter obtained by cardiopulmonary exercise testing (CPET), i.e., cardiorespiratory fitness (CRF), expressed as weight-adjusted peak oxygen consumption (VO2peak/kg). Subjects/Methods: This observational cross-sectional study conducted on a population of 843 patients affected by obesity finally enrolled 500 subjects. Every patient underwent clinical, anthropometric, biochemical assessment and CPET. First, participants have been classified according to standard EOSS in five stages. Second, patients were reclassified according to the new modified EOSS (EOSS-CRF) based on their age- and gender-appropriate VO2peak/kg percentiles as reported in the healthy normal-weight population of the FRIEND registry. Results: VO2peak/kg was significantly different between standard EOSS classes 1 and 2 and classes 1 and 3 (ANCOVA pmodel = 0.004), whereas patients in classes 2 and 3 showed similar CRF. The EOSS-CRF classification varied in number of patients in each class compared to EOSS, particularly with a shift from class 2 to class 3. Moreover, CRF showed that physical impairment is less addressed by EOSS when compared to EOSS-CRF. Conclusions: The integration of EOSS with CRF allowed us to assign to each patient a severity index that considers not only clinical parameters, but also their functional impairment through a quantitative and prognostically important parameter (VO2peak/kg). This improvement of the staging system may also provide a better approach to identify individuals at increased risk of mortality leading to targeted therapeutic management and prognostic risk stratification for patients with obesity.

Published
2024
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16. Hematopoietic stem cells and metabolic deterioration in Alström syndrome, a rare genetic model of the metabolic syndrome

Author

Dassie, Francesca, primary, Albiero, Mattia, additional, Bettini, Silvia, additional, Cappellari, Roberta, additional, Milan, Gabriella, additional, Ciciliot, Stefano, additional, Naggert, Jurgen K, additional, Avogaro, Angelo, additional, Vettor, Roberto, additional, Maffei, Pietro, additional, and Fadini, Gian Paolo, additional

Published
2023
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22. Case Report: Pregnancy and birth in a mild phenotype of Alström syndrome.

Author

Marozio, Luca, Dassie, Francesca, Bertschy, Gianluca, Canuto, Emilie M., Milan, Gabriella, Cosma, Stefano, Maffei, Pietro, and Benedetto, Chiara

Subjects
PREECLAMPSIA, NON-alcoholic fatty liver disease, WEIGHT gain, PREGNANCY, HYPERTENSION, ENDOCRINE diseases
Abstract

Background: Alström syndrome (AS) is an ultrarare multisystemic progressive disease caused by autosomal recessive variations of the ALMS1 gene (2p13). AS is characterized by double sensory impairment, cardiomyopathy, childhood obesity, extreme insulin resistance, early nonalcoholic fatty liver disease, renal dysfunction, respiratory disease, endocrine and urologic disorders. In female AS patients, hyperandrogenism has been described but fertility issues and conception have not been investigated so far. Case: This case report describes the spontaneous conception, pregnancy, and birth in a 27-year-old woman with AS, characterized by a mild phenotype with late onset of visual impairment, residual perception of light, and hypertension. Before pregnancy, menses were regular with increased levels of dihydrotestosterone and androstanediol glucuronide in the follicular phase, and the ovaries and endometrium were normal during vaginal ultrasound. A thorough clinical follow-up of the maternal and fetal conditions was carried out. A weight gain of 10 kg during pregnancy was recorded, and serial blood and urine tests were all within the normal range, except for mild anemia. The course of pregnancy was uneventful up to 34 weeks of gestation when preeclampsia developed with an abnormally high level of blood pressure and edema in the lower limbs. At 35 weeks + 3 days of gestation, an urgent cesarean section was performed, and a healthy male weighing 1,950 g was born. Histological examination of the placenta showed partial signs of flow obstruction, limited abruption areas, congested fetal vessels and villi, and a small single infarcted area. Conclusion: The present case demonstrates for the first time that conceiving is possible for patients with ALMS. Particular attention should be given to the management of AS systemic comorbidities through the course of pregnancy. [ABSTRACT FROM AUTHOR]

Published
2022
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