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Study curried out to evolution response growth and biochemical of Ocimum basilicum L. under drought conditions. Plant grown under treatment conditions (24 hours with - 54°C, 21°C, 55-70% RH) and plant were transferred to growth chamber for 6 weeks. The results showed that the rate of increase in chlorophyll a and b was significant with an increase rate of 1.7 and 0.6 compared to control after three days of treatment. The results also showed that H2O2 content was increased and reached to 1.3, 2.8 and 3.5X compared to the control after three, six and nine days of treatment respectively. One the other hand the levels of the enzyme APX activity, Lipid peroxidation and protein which was conducted on the tissue of basil leaves, increase compared with control after three days of treatment.